| Year |
Citation |
Score |
| 2010 |
Weeks JL, Conti M. The cAMP-specific phosphodiesterases. a class of diverse enzymes that define the properties and localization of camp signals Handbook of Cell Signaling, 2/E. 2: 1415-1423. DOI: 10.1016/B978-0-12-374145-5.00174-1 |
0.475 |
|
| 2009 |
Weeks JL, Corbin JD, Francis SH. Interactions between cyclic nucleotide phosphodiesterase 11 catalytic site and substrates or tadalafil and role of a critical Gln-869 hydrogen bond. The Journal of Pharmacology and Experimental Therapeutics. 331: 133-41. PMID 19641165 DOI: 10.1124/Jpet.109.156935 |
0.616 |
|
| 2007 |
Weeks JL, Zoraghi R, Francis SH, Corbin JD. N-Terminal domain of phosphodiesterase-11A4 (PDE11A4) decreases affinity of the catalytic site for substrates and tadalafil, and is involved in oligomerization. Biochemistry. 46: 10353-64. PMID 17696499 DOI: 10.1021/Bi7009629 |
0.569 |
|
| 2007 |
Corbin J, Bessay EP, Blount MA, Zoraghi R, Morris GZ, Weeks JL, Ke H, Francis SH. Negative feedback control of the nitric oxide/cGMP pathway in smooth muscle Bmc Pharmacology. 7. DOI: 10.1186/1471-2210-7-S1-S30 |
0.668 |
|
| 2005 |
Weeks JL, Blount MA, Beasley A, Zoraghi R, Thomas MK, Sekhar KR, Corbin JD, Francis SH. Radiolabeled ligand binding to the catalytic or allosteric sites of PDE5 and PDE11. Methods in Molecular Biology (Clifton, N.J.). 307: 239-62. PMID 15988068 DOI: 10.1385/1-59259-839-0:239 |
0.69 |
|
| 2005 |
Weeks JL, Zoraghi R, Beasley A, Sekhar KR, Francis SH, Corbin JD. High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients. International Journal of Impotence Research. 17: 5-9. PMID 15538396 DOI: 10.1038/Sj.Ijir.3901283 |
0.515 |
|
| 2003 |
Corbin JD, Blount MA, Weeks JL, Beasley A, Kuhn KP, Ho YS, Saidi LF, Hurley JH, Kotera J, Francis SH. [3H]sildenafil binding to phosphodiesterase-5 is specific, kinetically heterogeneous, and stimulated by cGMP. Molecular Pharmacology. 63: 1364-72. PMID 12761347 DOI: 10.1124/Mol.63.6.1364 |
0.672 |
|
| 2003 |
Weeks JL, Blount MA, Beasley A, Kotera J, Ho YS, Kuhn KP, Saidi LF, Hurley JH, Francis SH, Corbin JD. New features of PDE5 as revealed by a potent catalytic-site specific radioligand Bmc News and Views. 3. DOI: 10.1186/2048-4623-3-s2-p0054 |
0.655 |
|
| 2000 |
Menniti FS, Chenard BL, Collins MB, Ducat MF, Elliott ML, Ewing FE, Huang JI, Kelly KA, Lazzaro JT, Pagnozzi MJ, Weeks JL, Welch WM, Frost White W. Characterization of the binding site for a novel class of noncompetitive α-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor antagonists Molecular Pharmacology. 58: 1310-1317. PMID 11093768 |
0.396 |
|
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