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Je-In Youn, Ph.D. - Publications

Affiliations: 
2011 Biology (Cell Biology, Microbiology, Molecular Biology) University of South Florida, Tampa, FL, United States 
Area:
Immunology, Oncology
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Youn JI, Park SM, Park S, Kim G, Lee HJ, Son J, Hong MH, Ghaderpour A, Baik B, Islam J, Choi JW, Lee EY, Kim HR, Seo SU, Paik S, et al. Peripheral natural killer cells and myeloid-derived suppressor cells correlate with anti-PD-1 responses in non-small cell lung cancer. Scientific Reports. 10: 9050. PMID 32493990 DOI: 10.1038/S41598-020-65666-X  0.317
2019 Lee JW, Lee S, Ho JN, Youn JI, Byun SS, Lee E. Antitumor effects of MutT homolog 1 inhibitors in human bladder cancer cells. Bioscience, Biotechnology, and Biochemistry. 1-7. PMID 31362565 DOI: 10.1080/09168451.2019.1648207  0.35
2019 Ho JN, Byun SS, Lee SE, Youn JI, Lee S. Multikinase inhibitor motesanib enhances the antitumor effect of cisplatin in cisplatin‑resistant human bladder cancer cells via apoptosis and the PI3K/Akt pathway. Oncology Reports. PMID 30816494 DOI: 10.3892/or.2019.7005  0.361
2018 Kim HR, Park SM, Seo SU, Jung I, Yoon HI, Gabrilovich DI, Cho BC, Seong SY, Ha SJ, Youn JI. The Ratio of Peripheral Regulatory T Cells to Lox-1 PMN-MDSC Predicts the Early Response to Anti-PD-1 Therapy in Non-Small Cell Lung Cancer Patients. American Journal of Respiratory and Critical Care Medicine. PMID 30339766 DOI: 10.1164/Rccm.201808-1502Le  0.501
2018 Min CK, Kim HI, Ha NY, Kim Y, Kwon EK, Yen NTH, Youn JI, Jeon YK, Inn KS, Choi MS, Cho NH. A Type I Interferon and IL-10 Induced by Infection Suppresses Antigen-Specific T Cells and Their Memory Responses. Frontiers in Immunology. 9: 2022. PMID 30233599 DOI: 10.3389/Fimmu.2018.02022  0.307
2018 Hung AL, Maxwell R, Theodros D, Belcaid Z, Mathios D, Luksik AS, Kim E, Wu A, Xia Y, Garzon-Muvdi T, Jackson C, Ye X, Tyler B, Selby M, Korman A, ... ... Youn JI, et al. TIGIT and PD-1 dual checkpoint blockade enhances antitumor immunity and survival in GBM. Oncoimmunology. 7: e1466769. PMID 30221069 DOI: 10.1080/2162402X.2018.1466769  0.395
2016 Condamine T, Dominguez GA, Youn JI, Kossenkov AV, Mony S, Alicea-Torres K, Tcyganov E, Hashimoto A, Nefedova Y, Lin C, Partlova S, Garfall A, Vogl DT, Xu X, Knight SC, et al. Lectin-type oxidized LDL receptor-1 distinguishes population of human polymorphonuclear myeloid-derived suppressor cells in cancer patients. Science Immunology. 1. PMID 28417112 DOI: 10.1126/Sciimmunol.Aaf8943  0.618
2016 Jang E, Cho WS, Oh YK, Cho ML, Kim JM, Paik DJ, Youn J. Splenic Long-Lived Plasma Cells Promote the Development of Follicular Helper T Cells during Autoimmune Responses. Journal of Immunology (Baltimore, Md. : 1950). PMID 26729802 DOI: 10.4049/jimmunol.1401059  0.32
2015 Jang E, Jeong M, Kim S, Jang K, Kang BK, Lee DY, Bae SC, Kim KS, Youn J. Infusion of human bone marrow-derived mesenchymal stem cells alleviates autoimmune nephritis in a lupus model by suppressing follicular helper T cell development. Cell Transplantation. PMID 25975931 DOI: 10.3727/096368915X688173  0.402
2015 Kim S, Park K, Choi J, Jang E, Paik DJ, Seong RH, Youn J. Foxp3+ regulatory T cells ensure B lymphopoiesis by inhibiting the granulopoietic activity of effector T cells in mouse bone marrow European Journal of Immunology. 45: 167-179. PMID 25348202 DOI: 10.1002/eji.201444532  0.393
2015 Condamine T, Ramachandran I, Youn JI, Gabrilovich DI. Regulation of tumor metastasis by myeloid-derived suppressor cells. Annual Review of Medicine. 66: 97-110. PMID 25341012 DOI: 10.1146/Annurev-Med-051013-052304  0.682
2015 Sahakian E, Powers JJ, Chen J, Deng SL, Cheng F, Distler A, Woods DM, Rock-Klotz J, Sodre AL, Youn JI, Woan KV, Villagra A, Gabrilovich D, Sotomayor EM, Pinilla-Ibarz J. Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function. Molecular Immunology. 63: 579-85. PMID 25155994 DOI: 10.1016/J.Molimm.2014.08.002  0.672
2014 Condamine T, Kumar V, Ramachandran IR, Youn JI, Celis E, Finnberg N, El-Deiry WS, Winograd R, Vonderheide RH, English NR, Knight SC, Yagita H, McCaffrey JC, Antonia S, Hockstein N, et al. ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis. The Journal of Clinical Investigation. 124: 2626-39. PMID 24789911 DOI: 10.1172/Jci74056  0.619
2014 Cheng P, Kumar V, Liu H, Youn JI, Fishman M, Sherman S, Gabrilovich D. Effects of notch signaling on regulation of myeloid cell differentiation in cancer. Cancer Research. 74: 141-52. PMID 24220241 DOI: 10.1158/0008-5472.Can-13-1686  0.614
2013 Chen X, Eksioglu EA, Zhou J, Zhang L, Djeu J, Fortenbery N, Epling-Burnette P, Van Bijnen S, Dolstra H, Cannon J, Youn JI, Donatelli SS, Qin D, De Witte T, Tao J, et al. Induction of myelodysplasia by myeloid-derived suppressor cells. The Journal of Clinical Investigation. 123: 4595-611. PMID 24216507 DOI: 10.1172/Jci67580  0.615
2013 Nagaraj S, Youn JI, Gabrilovich DI. Reciprocal relationship between myeloid-derived suppressor cells and T cells. Journal of Immunology (Baltimore, Md. : 1950). 191: 17-23. PMID 23794702 DOI: 10.4049/Jimmunol.1300654  0.7
2013 Youn JI, Gabrilovich DI. New roles of Rb1 in expansion of MDSCs in cancer. Cell Cycle (Georgetown, Tex.). 12: 1329-30. PMID 23588070 DOI: 10.4161/Cc.24577  0.723
2013 Youn JI, Kumar V, Collazo M, Nefedova Y, Condamine T, Cheng P, Villagra A, Antonia S, McCaffrey JC, Fishman M, Sarnaik A, Horna P, Sotomayor E, Gabrilovich DI. Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer. Nature Immunology. 14: 211-20. PMID 23354483 DOI: 10.1038/Ni.2526  0.664
2013 Youn J, Kumar V, Collazo M, Gabrilovich DI. Abstract 1515: Epigenetic silencing of retinoblastoma gene regulates pathologic differentiation of myeloid cells in cancer. Cancer Research. 73: 1515-1515. DOI: 10.1158/1538-7445.Am2013-1515  0.67
2012 Nagaraj S, Nelson A, Youn JI, Cheng P, Quiceno D, Gabrilovich DI. Antigen-specific CD4(+) T cells regulate function of myeloid-derived suppressor cells in cancer via retrograde MHC class II signaling. Cancer Research. 72: 928-38. PMID 22237629 DOI: 10.1158/0008-5472.Can-11-2863  0.632
2012 Youn JI, Collazo M, Shalova IN, Biswas SK, Gabrilovich DI. Characterization of the nature of granulocytic myeloid-derived suppressor cells in tumor-bearing mice. Journal of Leukocyte Biology. 91: 167-81. PMID 21954284 DOI: 10.1189/Jlb.0311177  0.638
2012 Youn J, Collazo M, Kumar V, Gabrilovich DI. Abstract 5411: Rb1 controls the differentiation of myeloid-derived suppressor cells subsets Immunology. 72: 5411-5411. DOI: 10.1158/1538-7445.Am2012-5411  0.587
2012 Condamine T, Cheng P, Youn J, Ortiz ML, Vogl T, Roth J, Gabrilovich DI. Abstract 5399: S100A9 drives MDSC migration and contributes to tumor progression by inhibiting the immune response Cancer Research. 72: 5399-5399. DOI: 10.1158/1538-7445.Am2012-5399  0.704
2011 Lu T, Ramakrishnan R, Altiok S, Youn JI, Cheng P, Celis E, Pisarev V, Sherman S, Sporn MB, Gabrilovich D. Tumor-infiltrating myeloid cells induce tumor cell resistance to cytotoxic T cells in mice. The Journal of Clinical Investigation. 121: 4015-29. PMID 21911941 DOI: 10.1172/Jci45862  0.646
2011 Cao M, Xu Y, Youn JI, Cabrera R, Zhang X, Gabrilovich D, Nelson DR, Liu C. Kinase inhibitor Sorafenib modulates immunosuppressive cell populations in a murine liver cancer model. Laboratory Investigation; a Journal of Technical Methods and Pathology. 91: 598-608. PMID 21321535 DOI: 10.1038/Labinvest.2010.205  0.669
2011 Condamine T, Cheng P, Youn J, Ortiz ML, Vogl T, Roth J, Gabrilovich DI. Abstract 3648: S100A9 play a role in MDSC expansion and migration but not in their activation Cancer Research. 71: 3648-3648. DOI: 10.1158/1538-7445.Am2011-3648  0.717
2011 Youn J, Collazo MM, Gabrilovich D. Abstract 3647: Characterization of the relationship between mature neutrophils and tumor associated granulocytic myeloid-derived suppressor cells Cancer Research. 71: 3647-3647. DOI: 10.1158/1538-7445.Am2011-3647  0.625
2011 Ortiz ML, Cheng P, Luetteke N, Youn J, Gabrilovich DI. Abstract 3646: The role of myeloid-derived suppressor cells in tumor development Cancer Research. 71: 3646-3646. DOI: 10.1158/1538-7445.Am2011-3646  0.624
2010 Youn JI, Gabrilovich DI. The biology of myeloid-derived suppressor cells: the blessing and the curse of morphological and functional heterogeneity. European Journal of Immunology. 40: 2969-75. PMID 21061430 DOI: 10.1002/Eji.201040895  0.679
2010 Corzo CA, Condamine T, Lu L, Cotter MJ, Youn JI, Cheng P, Cho HI, Celis E, Quiceno DG, Padhya T, McCaffrey TV, McCaffrey JC, Gabrilovich DI. HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment. The Journal of Experimental Medicine. 207: 2439-53. PMID 20876310 DOI: 10.1084/Jem.20100587  0.746
2010 Nagaraj S, Youn JI, Weber H, Iclozan C, Lu L, Cotter MJ, Meyer C, Becerra CR, Fishman M, Antonia S, Sporn MB, Liby KT, Rawal B, Lee JH, Gabrilovich DI. Anti-inflammatory triterpenoid blocks immune suppressive function of MDSCs and improves immune response in cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 1812-23. PMID 20215551 DOI: 10.1158/1078-0432.Ccr-09-3272  0.611
2009 Nagaraj S, Collazo M, Corzo CA, Youn JI, Ortiz M, Quiceno D, Gabrilovich DI. Regulatory myeloid suppressor cells in health and disease. Cancer Research. 69: 7503-6. PMID 19752086 DOI: 10.1158/0008-5472.Can-09-2152  0.712
2009 Zhou J, Cheng P, Youn JI, Cotter MJ, Gabrilovich DI. Notch and wingless signaling cooperate in regulation of dendritic cell differentiation. Immunity. 30: 845-59. PMID 19523851 DOI: 10.1016/J.Immuni.2009.03.021  0.549
2008 Youn JI, Nagaraj S, Collazo M, Gabrilovich DI. Subsets of myeloid-derived suppressor cells in tumor-bearing mice. Journal of Immunology (Baltimore, Md. : 1950). 181: 5791-802. PMID 18832739 DOI: 10.4049/Jimmunol.181.8.5791  0.692
2008 Kim DJ, Youn JI, Seo SH, Jin HT, Sung YC. Differential regulation of antigen-specific CD8+ T cell responses by IL-12p40 in a dose-dependent manner. Journal of Immunology (Baltimore, Md. : 1950). 180: 7167-74. PMID 18490715 DOI: 10.4049/Jimmunol.180.11.7167  0.317
2007 Youn J, Jin H, Sung Y. Enhancement of Transduction Efficiency and Antitumor Effects of IL-12N220L-expressing Adenovirus by Co-delivery of DOTAP Immune Network. 7: 179-185. DOI: 10.4110/In.2007.7.4.179  0.39
2005 Jin HT, Youn JI, Kim HJ, Lee JB, Ha SJ, Koh JS, Sung YC. Enhancement of interleukin-12 gene-based tumor immunotherapy by the reduced secretion of p40 subunit and the combination with farnesyltransferase inhibitor. Human Gene Therapy. 16: 328-38. PMID 15812228 DOI: 10.1089/Hum.2005.16.328  0.352
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