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Benjamin Deneen - Publications

Affiliations: 
Glial cell Baylor College of Medicine, Houston, TX 

69 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Kwon W, Choi DJ, Yu K, Williamson MR, Murali S, Ko Y, Woo J, Deneen B. Comparative Transcriptomic Analysis of Cerebellar Astrocytes across Developmental Stages and Brain Regions. International Journal of Molecular Sciences. 25. PMID 38256095 DOI: 10.3390/ijms25021021  0.69
2023 Huang-Hobbs E, Cheng YT, Ko Y, Luna-Figueroa E, Lozzi B, Taylor KR, McDonald M, He P, Chen HC, Yang Y, Maleki E, Lee ZF, Murali S, Williamson MR, Choi D, ... ... Deneen B, et al. Remote neuronal activity drives glioma progression through SEMA4F. Nature. PMID 37380778 DOI: 10.1038/s41586-023-06267-2  0.696
2023 Sardar D, Cheng YT, Woo J, Choi DJ, Lee ZF, Kwon W, Chen HC, Lozzi B, Cervantes A, Rajendran K, Huang TW, Jain A, Arenkiel BR, Maze I, Deneen B. Induction of astrocytic Slc22a3 regulates sensory processing through histone serotonylation. Science (New York, N.Y.). 380: eade0027. PMID 37319217 DOI: 10.1126/science.ade0027  0.725
2023 Cheng YT, Luna-Figueroa E, Woo J, Chen HC, Lee ZF, Harmanci AS, Deneen B. Inhibitory input directs astrocyte morphogenesis through glial GABAR. Nature. PMID 37100909 DOI: 10.1038/s41586-023-06010-x  0.743
2023 Huang-Hobbs E, Cheng YT, Ko Y, Luna-Figueroa E, Lozzi B, Taylor KR, McDonald M, He P, Chen HC, Yang Y, Maleki E, Lee ZF, Murali S, Williamson M, Choi D, ... ... Deneen B, et al. Remote neuronal activity drives glioma infiltration via Sema4f. Biorxiv : the Preprint Server For Biology. PMID 36993539 DOI: 10.1101/2023.03.15.532832  0.689
2023 Cheng YT, Luna-Figueroa E, Woo J, Chen HC, Lee ZF, Harmanci AS, Deneen B. Inhibitory input directs astrocyte morphogenesis through glial GABA R. Biorxiv : the Preprint Server For Biology. PMID 36993256 DOI: 10.1101/2023.03.14.532493  0.726
2023 Sardar D, Cheng YT, Woo J, Choi DJ, Lee ZF, Kwon W, Chen HC, Lozzi B, Cervantes A, Rajendran K, Huang TW, Jain A, Arenkiel B, Maze I, Deneen B. Activity-dependent induction of astrocytic Slc22a3 regulates sensory processing through histone serotonylation. Biorxiv : the Preprint Server For Biology. PMID 36909526 DOI: 10.1101/2023.02.24.529904  0.723
2023 Cheng YT, Woo J, Luna-Figueroa E, Maleki E, Harmanci AS, Deneen B. Social deprivation induces astrocytic TRPA1-GABA suppression of hippocampal circuits. Neuron. PMID 36787749 DOI: 10.1016/j.neuron.2023.01.015  0.634
2022 Gu T, Hao D, Woo J, Huang TW, Guo L, Lin X, Guzman AG, Tovy A, Rosas C, Jeong M, Zhou Y, Deneen B, Huang Y, Li W, Goodell MA. The disordered N-terminal domain of DNMT3A recognizes H2AK119ub and is required for postnatal development. Nature Genetics. PMID 35534561 DOI: 10.1038/s41588-022-01063-6  0.65
2022 Cheng YT, Woo J, Deneen B. Sculpting Astrocyte Diversity through Circuits and Transcription. The Neuroscientist : a Review Journal Bringing Neurobiology, Neurology and Psychiatry. 10738584221082620. PMID 35373633 DOI: 10.1177/10738584221082620  0.709
2022 Cvetkovic C, Patel R, Shetty A, Hogan MK, Anderson M, Basu N, Aghlara-Fotovat S, Ramesh S, Sardar D, Veiseh O, Ward ME, Deneen B, Horner PJ, Krencik R. Assessing Gq-GPCR-induced human astrocyte reactivity using bioengineered neural organoids. The Journal of Cell Biology. 221. PMID 35139144 DOI: 10.1083/jcb.202107135  0.365
2022 Krawczyk MC, Haney JR, Pan L, Caneda C, Khankan RR, Reyes SD, Chang JW, Morselli M, Vinters HV, Wang AC, Cobos I, Gandal MJ, Bergsneider M, Kim W, Liau LM, ... ... Deneen B, et al. Human Astrocytes Exhibit Tumor Microenvironment-, Age-, and Sex-Related Transcriptomic Signatures. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34987109 DOI: 10.1523/JNEUROSCI.0407-21.2021  0.314
2021 Akdemir ES, Woo J, Bosquez Huerta NA, Lozzi B, Groves AK, Harmanci AS, Deneen B. Lunatic Fringe-GFP Marks Lamina-Specific Astrocytes That Regulate Sensory Processing. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34872929 DOI: 10.1523/JNEUROSCI.1392-21.2021  0.724
2021 Ung K, Huang TW, Lozzi B, Woo J, Hanson E, Pekarek B, Tepe B, Sardar D, Cheng YT, Liu G, Deneen B, Arenkiel BR. Olfactory bulb astrocytes mediate sensory circuit processing through Sox9 in the mouse brain. Nature Communications. 12: 5230. PMID 34471129 DOI: 10.1038/s41467-021-25444-3  0.732
2021 Huang TW, Iyer AA, Manalo JM, Woo J, Bosquez Huerta NA, McGovern MM, Schrewe H, Pereira FA, Groves AK, Ohlemiller KK, Deneen B. Glial-Specific Deletion of Med12 Results in Rapid Hearing Loss via Degradation of the Stria Vascularis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34253626 DOI: 10.1523/JNEUROSCI.0070-21.2021  0.654
2021 Huang TW, Iyer AA, Manalo JM, Woo J, Bosquez Huerta NA, McGovern MM, Schrewe H, Pereira FA, Groves AK, Ohlemiller KK, Deneen B. Glial-Specific Deletion of Med12 Results in Rapid Hearing Loss via Degradation of the Stria Vascularis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 34253626 DOI: 10.1523/JNEUROSCI.0070-21.2021  0.654
2021 Sardar D, Lozzi B, Woo J, Huang TW, Cvetkovic C, Creighton CJ, Krencik R, Deneen B. Mapping Astrocyte Transcriptional Signatures in Response to Neuroactive Compounds. International Journal of Molecular Sciences. 22. PMID 33921461 DOI: 10.3390/ijms22083975  0.735
2021 Escartin C, Galea E, Lakatos A, O'Callaghan JP, Petzold GC, Serrano-Pozo A, Steinhäuser C, Volterra A, Carmignoto G, Agarwal A, Allen NJ, Araque A, Barbeito L, Barzilai A, Bergles DE, ... ... Deneen B, et al. Reactive astrocyte nomenclature, definitions, and future directions. Nature Neuroscience. PMID 33589835 DOI: 10.1038/s41593-020-00783-4  0.482
2020 Ung K, Tepe B, Pekarek B, Arenkiel BR, Deneen B. Parallel astrocyte calcium signaling modulates olfactory bulb responses. Journal of Neuroscience Research. PMID 32426930 DOI: 10.1002/Jnr.24634  0.421
2020 Huang AY, Woo J, Sardar D, Lozzi B, Bosquez Huerta NA, Lin CJ, Felice D, Jain A, Paulucci-Holthauzen A, Deneen B. Region-Specific Transcriptional Control of Astrocyte Function Oversees Local Circuit Activities. Neuron. PMID 32320644 DOI: 10.1016/J.Neuron.2020.03.025  0.74
2020 Akdemir ES, Huang AY, Deneen B. Astrocytogenesis: where, when, and how. F1000research. 9. PMID 32269761 DOI: 10.12688/f1000research.22405.1  0.335
2020 Hatcher A, Yu K, Meyer J, Aiba I, Deneen B, Noebels JL. Pathogenesis of peritumoral hyperexcitability in an immunocompetent CRISPR-based glioblastoma model. The Journal of Clinical Investigation. PMID 32250339 DOI: 10.1172/Jci133316  0.345
2020 Lozzi B, Huang TW, Sardar D, Huang AY, Deneen B. Regionally Distinct Astrocytes Display Unique Transcription Factor Profiles in the Adult Brain. Frontiers in Neuroscience. 14: 61. PMID 32153350 DOI: 10.3389/Fnins.2020.00061  0.491
2020 Yu K, Lin CJ, Hatcher A, Lozzi B, Kong K, Huang-Hobbs E, Cheng YT, Beechar VB, Zhu W, Zhang Y, Chen F, Mills GB, Mohila CA, Creighton CJ, Noebels JL, ... ... Deneen B, et al. PIK3CA variants selectively initiate brain hyperactivity during gliomagenesis. Nature. PMID 31996845 DOI: 10.1038/S41586-020-1952-2  0.459
2019 Laug D, Huang TW, Huerta NAB, Huang AY, Sardar D, Ortiz-Guzman J, Carlson JC, Arenkiel BR, Kuo CT, Mohila CA, Glasgow SM, Lee HK, Deneen B. Nuclear factor I-A regulates diverse reactive astrocyte responses after CNS injury. The Journal of Clinical Investigation. PMID 31498149 DOI: 10.1172/Jci127492  0.573
2019 Khakh BS, Deneen B. The Emerging Nature of Astrocyte Diversity. Annual Review of Neuroscience. 42: 187-207. PMID 31283899 DOI: 10.1146/Annurev-Neuro-070918-050443  0.419
2019 Wang CY, Deneen B, Tzeng SF. BRCA1/BRCA2-containing complex subunit 3 controls oligodendrocyte differentiation by dynamically regulating lysine 63-linked ubiquitination. Glia. PMID 31184779 DOI: 10.1002/Glia.23660  0.38
2019 Cuevas-Diaz Duran R, Wang CY, Zheng H, Deneen B, Wu JQ. Brain Region-Specific Gene Signatures Revealed by Distinct Astrocyte Subpopulations Unveil Links to Glioma and Neurodegenerative Diseases. Eneuro. 6. PMID 30957015 DOI: 10.1523/ENEURO.0288-18.2019  0.339
2018 Scavuzzo MA, Chmielowiec J, Yang D, Wamble K, Chaboub LS, Duraine L, Tepe B, Glasgow SM, Arenkiel BR, Brou C, Deneen B, Borowiak M. Pancreatic Cell Fate Determination Relies on Notch Ligand Trafficking by NFIA. Cell Reports. 25: 3811-3827.e7. PMID 30590051 DOI: 10.1016/J.Celrep.2018.11.078  0.388
2018 Laug D, Glasgow SM, Deneen B. A glial blueprint for gliomagenesis. Nature Reviews. Neuroscience. PMID 29777182 DOI: 10.1038/S41583-018-0014-3  0.442
2018 Danussi C, Bose P, Parthasarathy PT, Silberman PC, Van Arnam JS, Vitucci M, Tang OY, Heguy A, Wang Y, Chan TA, Riggins GJ, Sulman EP, Lang F, Creighton CJ, Deneen B, et al. Atrx inactivation drives disease-defining phenotypes in glioma cells of origin through global epigenomic remodeling. Nature Communications. 9: 1057. PMID 29535300 DOI: 10.1038/S41467-018-03476-6  0.444
2018 Kfoury N, Sun T, Yu K, Rockwell N, Tinkum KL, Qi Z, Warrington NM, McDonald P, Roy A, Weir SJ, Mohila CA, Deneen B, Rubin JB. Cooperative p16 and p21 action protects female astrocytes from transformation. Acta Neuropathologica Communications. 6: 12. PMID 29458417 DOI: 10.1186/S40478-018-0513-5  0.348
2018 Yu K, Hatcher A, Woo J, John Lin C, Kong K, Mohila C, Lozzi B, Creighton C, Noebels J, Deneen B. CBMT-23. MODULATION OF HYPERSYNAPTIC MICROENVIRONMENT DIFFERENTIALLY PROMOTES GLIOMAGENESIS ACROSS PIK3CA VARIANTS Neuro-Oncology. 20: vi37-vi37. DOI: 10.1093/Neuonc/Noy148.142  0.314
2017 Zhu W, Krishna S, Garcia C, Lin CJ, Mitchell BD, Scott KL, Mohila CA, Creighton CJ, Yoo SH, Lee HK, Deneen B. Daam2 driven degradation of VHL promotes gliomagenesis. Elife. 6. PMID 29053101 DOI: 10.7554/Elife.31926  0.529
2017 Glasgow SM, Carlson JC, Zhu W, Chaboub LS, Kang P, Lee HK, Clovis YM, Lozzi BE, McEvilly RJ, Rosenfeld MG, Creighton CJ, Lee SK, Mohila CA, Deneen B. Glia-specific enhancers and chromatin structure regulate NFIA expression and glioma tumorigenesis. Nature Neuroscience. PMID 28892058 DOI: 10.1038/Nn.4638  0.609
2017 Wang CY, Deneen B, Tzeng SF. MicroRNA-212 inhibits oligodendrocytes during maturation by downregulation of differentiation-associated gene expression. Journal of Neurochemistry. PMID 28771716 DOI: 10.1111/Jnc.14138  0.332
2017 John Lin CC, Yu K, Hatcher A, Huang TW, Lee HK, Carlson J, Weston MC, Chen F, Zhang Y, Zhu W, Mohila CA, Ahmed N, Patel AJ, Arenkiel BR, Noebels JL, ... ... Deneen B, et al. Identification of diverse astrocyte populations and their malignant analogs. Nature Neuroscience. PMID 28166219 DOI: 10.1038/Nn.4493  0.579
2017 Glasgow SM, Deneen B. lnc'edin to Myelin. Neuron. 93: 252-254. PMID 28103473 DOI: 10.1016/J.Neuron.2017.01.002  0.301
2017 Zhu W, Krishna S, Garcia C, Lin CJ, Mitchell BD, Scott KL, Mohila CA, Creighton CJ, Yoo S, Lee HK, Deneen B. Author response: Daam2 driven degradation of VHL promotes gliomagenesis Elife. DOI: 10.7554/Elife.31926.019  0.423
2017 Danussi C, Bose P, Parthasarathy P, Silberman P, Arnam JSV, Vitucci M, Tang O, Heguy A, Chan T, Sulman E, Lang F, Creighton CJ, Deneen B, Miller CR, Picketts D, et al. Gene-24. Atrx Deficiency In Glioma Cells Of Origin Promotes Disease-Defining Phenotypes By Way Of Global Epigenomic Remodeling Neuro-Oncology. 19. DOI: 10.1093/Neuonc/Nox168.398  0.336
2016 Chaboub LS, Manalo JM, Lee HK, Glasgow SM, Chen F, Kawasaki Y, Akiyama T, Kuo CT, Creighton CJ, Mohila CA, Deneen B. Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 11904-11917. PMID 27881777 DOI: 10.1523/Jneurosci.1658-16.2016  0.581
2015 Molofsky AV, Deneen B. Astrocyte development: A Guide for the Perplexed. Glia. 63: 1320-9. PMID 25963996 DOI: 10.1002/Glia.22836  0.504
2015 Lee HK, Laug D, Zhu W, Patel JM, Ung K, Arenkiel BR, Fancy SP, Mohila C, Deneen B. Apcdd1 stimulates oligodendrocyte differentiation after white matter injury. Glia. PMID 25946682 DOI: 10.1002/Glia.22848  0.541
2015 Lee HK, Chaboub LS, Zhu W, Zollinger D, Rasband MN, Fancy SP, Deneen B. Daam2-PIP5K is a regulatory pathway for Wnt signaling and therapeutic target for remyelination in the CNS. Neuron. 85: 1227-43. PMID 25754822 DOI: 10.1016/J.Neuron.2015.02.024  0.511
2015 Yu K, Carlson J, Lin CJ, Zhu W, Ahmed N, Li X, Mohila C, Monje M, Patel AJ, Deneen B. CBIO-48DECODING THE CELLULAR HETEROGENEITY OF MALIGNANT GLIOMA Neuro-Oncology. 17: v64.5-v65. DOI: 10.1093/Neuonc/Nov209.48  0.357
2015 Zhu W, Lee H, Loturco J, Mohila C, Deneen B. HG-05 * DAAM2 PROMOTES TUMOR PROLIFERATION AND MIGRATION IN GLIOBLASTOMA Neuro-Oncology. 17: iii11-iii11. DOI: 10.1093/Neuonc/Nov061.42  0.418
2015 Yu K, Carlson J, Lin CCJ, Zhu W, Ahmed N, Li X, Mohila C, Monje M, Patel AJ, Deneen B. PM-04 * DECODING THE CELLULAR HETEROGENEITY OF PEDIATRIC HIGH GRADE GLIOMA Neuro-Oncology. 17: iii31-iii31. DOI: 10.1093/Neuonc/Nov061.126  0.367
2014 Garcia I, Bhullar PK, Tepe B, Ortiz-Guzman J, Huang L, Herman AM, Chaboub L, Deneen B, Justice NJ, Arenkiel BR. Local corticotropin releasing hormone (CRH) signals to its receptor CRHR1 during postnatal development of the mouse olfactory bulb. Brain Structure & Function. PMID 25224546 DOI: 10.1007/S00429-014-0888-4  0.408
2014 Glasgow SM, Zhu W, Stolt CC, Huang TW, Chen F, LoTurco JJ, Neul JL, Wegner M, Mohila C, Deneen B. Mutual antagonism between Sox10 and NFIA regulates diversification of glial lineages and glioma subtypes. Nature Neuroscience. 17: 1322-9. PMID 25151262 DOI: 10.1038/Nn.3790  0.452
2014 Gallo V, Deneen B. Glial development: the crossroads of regeneration and repair in the CNS. Neuron. 83: 283-308. PMID 25033178 DOI: 10.1016/J.Neuron.2014.06.010  0.406
2014 Lee JS, Xiao J, Patel P, Schade J, Wang J, Deneen B, Erdreich-Epstein A, Song HR. A novel tumor-promoting role for nuclear factor IA in glioblastomas is mediated through negative regulation of p53, p21, and PAI1. Neuro-Oncology. 16: 191-203. PMID 24305710 DOI: 10.1093/Neuonc/Not167  0.426
2013 John Lin CC, Deneen B. Astrocytes: the missing link in neurologic disease? Seminars in Pediatric Neurology. 20: 236-41. PMID 24365571 DOI: 10.1016/J.Spen.2013.10.004  0.449
2013 Chaboub LS, Deneen B. Astrocyte form and function in the developing central nervous system. Seminars in Pediatric Neurology. 20: 230-5. PMID 24365570 DOI: 10.1016/J.Spen.2013.10.003  0.425
2013 Glasgow SM, Laug D, Brawley VS, Zhang Z, Corder A, Yin Z, Wong ST, Li XN, Foster AE, Ahmed N, Deneen B. The miR-223/nuclear factor I-A axis regulates glial precursor proliferation and tumorigenesis in the CNS. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 13560-8. PMID 23946414 DOI: 10.1523/Jneurosci.0321-13.2013  0.323
2013 Molofsky AV, Glasgow SM, Chaboub LS, Tsai HH, Murnen AT, Kelley KW, Fancy SP, Yuen TJ, Madireddy L, Baranzini S, Deneen B, Rowitch DH, Oldham MC. Expression profiling of Aldh1l1-precursors in the developing spinal cord reveals glial lineage-specific genes and direct Sox9-Nfe2l1 interactions. Glia. 61: 1518-32. PMID 23840004 DOI: 10.1002/Glia.22538  0.46
2012 Chaboub LS, Deneen B. Developmental origins of astrocyte heterogeneity: the final frontier of CNS development. Developmental Neuroscience. 34: 379-88. PMID 23147551 DOI: 10.1159/000343723  0.43
2012 Fancy SP, Glasgow SM, Finley M, Rowitch DH, Deneen B. Evidence that nuclear factor IA inhibits repair after white matter injury. Annals of Neurology. 72: 224-33. PMID 22807310 DOI: 10.1002/Ana.23590  0.389
2012 Molofsky AV, Krencik R, Krenick R, Ullian EM, Ullian E, Tsai HH, Deneen B, Richardson WD, Barres BA, Rowitch DH. Astrocytes and disease: a neurodevelopmental perspective. Genes & Development. 26: 891-907. PMID 22549954 DOI: 10.1101/Gad.188326.112  0.432
2012 Kang P, Lee HK, Glasgow SM, Finley M, Donti T, Gaber ZB, Graham BH, Foster AE, Novitch BG, Gronostajski RM, Deneen B. Sox9 and NFIA coordinate a transcriptional regulatory cascade during the initiation of gliogenesis. Neuron. 74: 79-94. PMID 22500632 DOI: 10.1016/J.Neuron.2012.01.024  0.565
2012 Lee HK, Deneen B. Daam2 is required for dorsal patterning via modulation of canonical Wnt signaling in the developing spinal cord. Developmental Cell. 22: 183-96. PMID 22227309 DOI: 10.1016/J.Devcel.2011.10.025  0.478
2010 Song HR, Gonzalez-Gomez I, Suh GS, Commins DL, Sposto R, Gilles FH, Deneen B, Erdreich-Epstein A. Nuclear factor IA is expressed in astrocytomas and is associated with improved survival. Neuro-Oncology. 12: 122-32. PMID 20150379 DOI: 10.1093/Neuonc/Nop044  0.718
2009 Namihira M, Kohyama J, Semi K, Sanosaka T, Deneen B, Taga T, Nakashima K. Committed neuronal precursors confer astrocytic potential on residual neural precursor cells. Developmental Cell. 16: 245-55. PMID 19217426 DOI: 10.1016/J.Devcel.2008.12.014  0.52
2009 Sanosaka T, Namihira M, Kohyama J, Semi K, Deneen B, Taga T, Nakashima k. Epigenetic mechanism conferring astrocytic potential on neural precursor cells Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.1591  0.376
2008 Hochstim C, Deneen B, Lukaszewicz A, Zhou Q, Anderson DJ. Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code. Cell. 133: 510-22. PMID 18455991 DOI: 10.1016/J.Cell.2008.02.046  0.696
2006 Deneen B, Ho R, Lukaszewicz A, Hochstim CJ, Gronostajski RM, Anderson DJ. The transcription factor NFIA controls the onset of gliogenesis in the developing spinal cord. Neuron. 52: 953-68. PMID 17178400 DOI: 10.1016/J.Neuron.2006.11.019  0.558
2006 Mukouyama YS, Deneen B, Lukaszewicz A, Novitch BG, Wichterle H, Jessell TM, Anderson DJ. Olig2+ neuroepithelial motoneuron progenitors are not multipotent stem cells in vivo. Proceedings of the National Academy of Sciences of the United States of America. 103: 1551-6. PMID 16432183 DOI: 10.1073/Pnas.0510658103  0.466
2003 Deneen B, Welford SM, Ho T, Hernandez F, Kurland I, Denny CT. PIM3 proto-oncogene kinase is a common transcriptional target of divergent EWS/ETS oncoproteins. Molecular and Cellular Biology. 23: 3897-908. PMID 12748291 DOI: 10.1128/Mcb.23.11.3897-3908.2003  0.354
2001 Deneen B, Denny CT. Loss of p16 pathways stabilizes EWS/FLI1 expression and complements EWS/FLI1 mediated transformation. Oncogene. 20: 6731-41. PMID 11709708 DOI: 10.1038/Sj.Onc.1204875  0.347
2001 Welford SM, Hebert SP, Deneen B, Arvand A, Denny CT. DNA binding domain-independent pathways are involved in EWS/FLI1-mediated oncogenesis. The Journal of Biological Chemistry. 276: 41977-84. PMID 11553628 DOI: 10.1074/Jbc.M106757200  0.316
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