| Year |
Citation |
Score |
| 2020 |
Kordowitzki P, López de Silanes I, Guío-Carrión A, Blasco MA. Dynamics of telomeric repeat-containing RNA expression in early embryonic cleavage stages with regards to maternal age. Aging. 12: 15906-15917. PMID 32860669 DOI: 10.18632/aging.103922 |
0.343 |
|
| 2019 |
Muñoz-Lorente MA, Cano-Martin AC, Blasco MA. Mice with hyper-long telomeres show less metabolic aging and longer lifespans. Nature Communications. 10: 4723. PMID 31624261 DOI: 10.1038/s41467-019-12664-x |
0.313 |
|
| 2019 |
Whittemore K, Derevyanko A, Martinez P, Serrano R, Pumarola M, Bosch F, Blasco MA. Telomerase gene therapy ameliorates the effects of neurodegeneration associated to short telomeres in mice. Aging. PMID 31140977 DOI: 10.18632/aging.101982 |
0.32 |
|
| 2018 |
Montero JJ, López-Silanes I, Megías D, F Fraga M, Castells-García Á, Blasco MA. TERRA recruitment of polycomb to telomeres is essential for histone trymethylation marks at telomeric heterochromatin. Nature Communications. 9: 1548. PMID 29670078 DOI: 10.1038/s41467-018-03916-3 |
0.311 |
|
| 2017 |
Marión RM, López de Silanes I, Mosteiro L, Gamache B, Abad M, Guerra C, Megías D, Serrano M, Blasco MA. Common Telomere Changes during In Vivo Reprogramming and Early Stages of Tumorigenesis. Stem Cell Reports. PMID 28162998 DOI: 10.1016/J.Stemcr.2017.01.001 |
0.305 |
|
| 2016 |
Martínez P, Gómez-López G, Pisano DG, Flores JM, Blasco MA. A genetic interaction between RAP1 and telomerase reveals an unanticipated role for RAP1 in telomere maintenance. Aging Cell. PMID 27586969 DOI: 10.1111/acel.12517 |
0.359 |
|
| 2016 |
Montero JJ, López de Silanes I, Graña O, Blasco MA. Telomeric RNAs are essential to maintain telomeres. Nature Communications. 7: 12534. PMID 27531349 DOI: 10.1038/ncomms12534 |
0.364 |
|
| 2016 |
Varela E, Muñoz-Lorente MA, Tejera AM, Ortega S, Blasco MA. Generation of mice with longer and better preserved telomeres in the absence of genetic manipulations. Nature Communications. 7: 11739. PMID 27252083 DOI: 10.1038/ncomms11739 |
0.32 |
|
| 2016 |
Fernández-Alvira JM, Fuster V, Dorado B, Soberón N, Flores I, Gallardo M, Pocock S, Blasco MA, Andrés V. Short Telomere Load, Telomere Length, and Subclinical Atherosclerosis: The PESA Study. Journal of the American College of Cardiology. 67: 2467-76. PMID 27230041 DOI: 10.1016/J.Jacc.2016.03.530 |
0.342 |
|
| 2014 |
Garrobo I, Marión RM, Domínguez O, Pisano DG, Blasco MA. Genome-wide analysis of in vivo TRF1 binding to chromatin restricts its location exclusively to telomeric repeats. Cell Cycle (Georgetown, Tex.). 13: 3742-9. PMID 25483083 DOI: 10.4161/15384101.2014.965044 |
0.33 |
|
| 2014 |
López de Silanes I, Graña O, De Bonis ML, Dominguez O, Pisano DG, Blasco MA. Identification of TERRA locus unveils a telomere protection role through association to nearly all chromosomes. Nature Communications. 5: 4723. PMID 25182072 DOI: 10.1038/ncomms5723 |
0.365 |
|
| 2012 |
Vera E, Bernardes de Jesus B, Foronda M, Flores JM, Blasco MA. The rate of increase of short telomeres predicts longevity in mammals. Cell Reports. 2: 732-7. PMID 23022483 DOI: 10.1016/j.celrep.2012.08.023 |
0.31 |
|
| 2012 |
Martinez-Delgado B, Yanowsky K, Inglada-Perez L, de la Hoya M, Caldes T, Vega A, Blanco A, Martin T, Gonzalez-Sarmiento R, Blasco M, Robledo M, Urioste M, Song H, Pharoah P, Benitez J. Shorter telomere length is associated with increased ovarian cancer risk in both familial and sporadic cases. Journal of Medical Genetics. 49: 341-4. PMID 22493152 DOI: 10.1136/Jmedgenet-2012-100807 |
0.301 |
|
| 2011 |
Bernardes de Jesus B, Schneeberger K, Vera E, Tejera A, Harley CB, Blasco MA. The telomerase activator TA-65 elongates short telomeres and increases health span of adult/old mice without increasing cancer incidence. Aging Cell. 10: 604-21. PMID 21426483 DOI: 10.1111/j.1474-9726.2011.00700.x |
0.348 |
|
| 2011 |
MartÃnez P, Blasco MA. Telomeric and extra-telomeric roles for telomerase and the telomere-binding proteins. Nature Reviews. Cancer. 11: 161-76. PMID 21346783 DOI: 10.1038/nrc3025 |
0.393 |
|
| 2011 |
Donate LE, Blasco MA. Telomeres in cancer and ageing. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 366: 76-84. PMID 21115533 DOI: 10.1098/rstb.2010.0291 |
0.399 |
|
| 2011 |
Harley CB, Liu W, Blasco M, Vera E, Andrews WH, Briggs LA, Raffaele JM. A natural product telomerase activator as part of a health maintenance program. Rejuvenation Research. 14: 45-56. PMID 20822369 DOI: 10.1089/Rej.2010.1085 |
0.338 |
|
| 2010 |
Palacios JA, Herranz D, De Bonis ML, Velasco S, Serrano M, Blasco MA. SIRT1 contributes to telomere maintenance and augments global homologous recombination. The Journal of Cell Biology. 191: 1299-313. PMID 21187328 DOI: 10.1083/jcb.201005160 |
0.306 |
|
| 2010 |
López de Silanes I, Stagno d'Alcontres M, Blasco MA. TERRA transcripts are bound by a complex array of RNA-binding proteins. Nature Communications. 1: 33. PMID 20975687 DOI: 10.1038/ncomms1032 |
0.337 |
|
| 2010 |
Tejera AM, Stagno d'Alcontres M, Thanasoula M, Marion RM, Martinez P, Liao C, Flores JM, Tarsounas M, Blasco MA. TPP1 is required for TERT recruitment, telomere elongation during nuclear reprogramming, and normal skin development in mice. Developmental Cell. 18: 775-89. PMID 20493811 DOI: 10.1016/j.devcel.2010.03.011 |
0.328 |
|
| 2010 |
McNees CJ, Tejera AM, Martínez P, Murga M, Mulero F, Fernandez-Capetillo O, Blasco MA. ATR suppresses telomere fragility and recombination but is dispensable for elongation of short telomeres by telomerase. The Journal of Cell Biology. 188: 639-52. PMID 20212315 DOI: 10.1083/Jcb.200908136 |
0.33 |
|
| 2010 |
Schoeftner S, Blasco MA. Chromatin regulation and non-coding RNAs at mammalian telomeres. Seminars in Cell & Developmental Biology. 21: 186-93. PMID 19815087 DOI: 10.1016/j.semcdb.2009.09.015 |
0.344 |
|
| 2009 |
Schoeftner S, Blanco R, Lopez de Silanes I, Muñoz P, Gómez-López G, Flores JM, Blasco MA. Telomere shortening relaxes X chromosome inactivation and forces global transcriptome alterations. Proceedings of the National Academy of Sciences of the United States of America. 106: 19393-8. PMID 19887628 DOI: 10.1073/Pnas.0909265106 |
0.302 |
|
| 2009 |
Martínez P, Thanasoula M, Muñoz P, Liao C, Tejera A, McNees C, Flores JM, Fernández-Capetillo O, Tarsounas M, Blasco MA. Increased telomere fragility and fusions resulting from TRF1 deficiency lead to degenerative pathologies and increased cancer in mice. Genes & Development. 23: 2060-75. PMID 19679647 DOI: 10.1101/Gad.543509 |
0.326 |
|
| 2009 |
Schoeftner S, Blasco MA. A 'higher order' of telomere regulation: telomere heterochromatin and telomeric RNAs. The Embo Journal. 28: 2323-36. PMID 19629032 DOI: 10.1038/emboj.2009.197 |
0.341 |
|
| 2009 |
Cipriano C, Tesei S, Malavolta M, Giacconi R, Muti E, Costarelli L, Piacenza F, Pierpaoli S, Galeazzi R, Blasco M, Vera E, Canela A, Lattanzio F, Mocchegiani E. Accumulation of cells with short telomeres is associated with impaired zinc homeostasis and inflammation in old hypertensive participants. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 64: 745-51. PMID 19359441 DOI: 10.1093/Gerona/Glp048 |
0.376 |
|
| 2009 |
Muñoz P, Blanco R, De Carcer G, Schoeftner S, Benetti R, Flores JM, Malumbres M, Blasco MA. TRF1 controls telomere length and mitotic fidelity in epithelial homeostasis Molecular and Cellular Biology. 29: 1608-1625. PMID 19124610 DOI: 10.1128/Mcb.01339-08 |
0.344 |
|
| 2009 |
Martinez P, Siegl-Cachedenier I, Flores JM, Blasco MA. MSH2 deficiency abolishes the anticancer and pro-aging activity of short telomeres Aging Cell. 8: 2-17. PMID 18986375 DOI: 10.1111/j.1474-9726.2008.00441.x |
0.335 |
|
| 2008 |
Tomás-Loba A, Flores I, Fernández-Marcos PJ, Cayuela ML, Maraver A, Tejera A, Borrás C, Matheu A, Klatt P, Flores JM, Viña J, Serrano M, Blasco MA. Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice Cell. 135: 609-622. PMID 19013273 DOI: 10.1016/j.cell.2008.09.034 |
0.316 |
|
| 2008 |
Benetti R, Schoeftner S, Muñoz P, Blasco MA. Role of TRF2 in the assembly of telomeric chromatin Cell Cycle. 7: 3461-3468. PMID 18971622 |
0.324 |
|
| 2008 |
Schoeftner S, Blasco MA. Developmentally regulated transcription of mammalian telomeres by DNA-dependent RNA polymerase II Nature Cell Biology. 10: 228-236. PMID 18157120 DOI: 10.1038/ncb1685 |
0.406 |
|
| 2007 |
Liu L, Bailey SM, Okuka M, Muñoz P, Li C, Zhou L, Wu C, Czerwiec E, Sandler L, Seyfang A, Blasco MA, Keefe DL. Telomere lengthening early in development. Nature Cell Biology. 9: 1436-41. PMID 17982445 DOI: 10.1038/Ncb1664 |
0.301 |
|
| 2007 |
Salvati E, Leonetti C, Rizzo A, Scarsella M, Mottolese M, Galati R, Sperduti I, Stevens MFG, D'Incalci M, Blasco M, Chiorino G, Bauwens S, Horard B, Gilson E, Stoppacciaro A, et al. Telomere damage induced by the G-quadruplex ligand RHPS4 has an antitumor effect Journal of Clinical Investigation. 117: 3236-3247. PMID 17932567 DOI: 10.1172/Jci32461 |
0.379 |
|
| 2007 |
Blasco MA. Telomere length, stem cells and aging Nature Chemical Biology. 3: 640-649. PMID 17876321 DOI: 10.1038/nchembio.2007.38 |
0.3 |
|
| 2007 |
Canela A, Klatt P, Blasco MA. Telomere length analysis. Methods in Molecular Biology (Clifton, N.J.). 371: 45-72. PMID 17634573 DOI: 10.1007/978-1-59745-361-5_5 |
0.302 |
|
| 2007 |
Blanco R, Muñoz P, Flores JM, Klatt P, Blasco MA. Telomerase abrogation dramatically accelerates TRF2-induced epithelial carcinogenesis. Genes & Development. 21: 206-20. PMID 17234886 DOI: 10.1101/Gad.406207 |
0.338 |
|
| 2006 |
Muñoz P, Blanco R, Blasco MA. Role of the TRF2 telomeric protein in cancer and ageing. Cell Cycle (Georgetown, Tex.). 5: 718-21. PMID 16582635 DOI: 10.4161/Cc.5.7.2636 |
0.375 |
|
| 2006 |
Geserick C, Blasco MA. Novel roles for telomerase in aging. Mechanisms of Ageing and Development. 127: 579-83. PMID 16516269 DOI: 10.1016/j.mad.2006.01.017 |
0.349 |
|
| 2005 |
Rodríguez S, Goyanes V, Segrelles E, Blasco M, Gosálvez J, Fernández JL. Critically short telomeres are associated with sperm DNA fragmentation. Fertility and Sterility. 84: 843-5. PMID 16213831 DOI: 10.1016/j.fertnstert.2005.05.014 |
0.301 |
|
| 2005 |
Blasco MA. Telomeres and human disease: ageing, cancer and beyond. Nature Reviews. Genetics. 6: 611-22. PMID 16136653 DOI: 10.1038/nrg1656 |
0.309 |
|
| 2005 |
Blasco MA. Mice with bad ends: mouse models for the study of telomeres and telomerase in cancer and aging. The Embo Journal. 24: 1095-103. PMID 15775986 DOI: 10.1038/sj.emboj.7600598 |
0.33 |
|
| 2004 |
Jaco I, Muñoz P, Blasco MA. Role of human Ku86 in telomere length maintenance and telomere capping. Cancer Research. 64: 7271-8. PMID 15492246 DOI: 10.1158/0008-5472.CAN-04-1381 |
0.395 |
|
| 2004 |
Franco S, van de Vrugt HJ, Fernández P, Aracil M, Arwert F, Blasco MA. Telomere dynamics in Fancg-deficient mouse and human cells. Blood. 104: 3927-35. PMID 15319283 DOI: 10.1182/blood-2003-10-3626 |
0.333 |
|
| 2004 |
Tarsounas M, Muñoz P, Claas A, Smiraldo PG, Pittman DL, Blasco MA, West SC. Telomere maintenance requires the RAD51D recombination/repair protein. Cell. 117: 337-47. PMID 15109494 DOI: 10.1016/S0092-8674(04)00337-X |
0.306 |
|
| 2004 |
Dantzer F, Giraud-Panis M, Jaco I, Amé J, Schultz I, Blasco M, Koering C, Gilson E, Murcia JM, Murcia Gd, Schreiber V. Functional Interaction between Poly(ADP-Ribose) Polymerase 2 (PARP-2) and TRF2: PARP Activity Negatively Regulates TRF2 Molecular and Cellular Biology. 24: 1595-1607. PMID 14749375 DOI: 10.1128/Mcb.24.4.1595-1607.2004 |
0.374 |
|
| 2004 |
Blasco MA, Hahn WC. Evolving views of telomerase and cancer. Trends in Cell Biology. 13: 289-94. PMID 12791294 DOI: 10.1016/S0962-8924(03)00085-0 |
0.323 |
|
| 2003 |
Poch E, Carbonell P, Franco S, Díez-Juan A, Blasco MA, Andrés V. Short telomeres protect from diet-induced atherosclerosis in apolipoprotein E-null mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 418-20. PMID 14688198 DOI: 10.1096/fj.03-0710fje |
0.336 |
|
| 2003 |
Blasco MA. Telomeres in cancer and aging: lessons from the mouse. Cancer Letters. 194: 183-8. PMID 12757976 DOI: 10.1016/s0304-3835(02)00705-x |
0.311 |
|
| 2003 |
Blasco MA. Mouse models to study the role of telomeres in cancer, aging and DNA repair. European Journal of Cancer (Oxford, England : 1990). 38: 2222-8. PMID 12441258 DOI: 10.1016/s0959-8049(02)00450-1 |
0.335 |
|
| 2002 |
García-Cao M, Gonzalo S, Dean D, Blasco MA. A role for the Rb family of proteins in controlling telomere length. Nature Genetics. 32: 415-9. PMID 12379853 DOI: 10.1038/Ng1011 |
0.33 |
|
| 2002 |
Blasco MA. Telomerase beyond telomeres. Nature Reviews. Cancer. 2: 627-33. PMID 12154355 DOI: 10.1038/nrc862 |
0.332 |
|
| 2002 |
Espejel S, Blasco MA. Identification of telomere-dependent "senescence-like" arrest in mouse embryonic fibroblasts. Experimental Cell Research. 276: 242-8. PMID 12027454 DOI: 10.1006/excr.2002.5533 |
0.355 |
|
| 2002 |
Espejel S, Franco S, Rodríguez-Perales S, Bouffler SD, Cigudosa JC, Blasco MA. Mammalian Ku86 mediates chromosomal fusions and apoptosis caused by critically short telomeres. The Embo Journal. 21: 2207-19. PMID 11980718 DOI: 10.1093/emboj/21.9.2207 |
0.333 |
|
| 2002 |
Blasco MA. Immunosenescence phenotypes in the telomerase knockout mouse. Springer Seminars in Immunopathology. 24: 75-85. PMID 11974584 DOI: 10.1007/s00281-001-0096-1 |
0.329 |
|
| 2002 |
Callén E, Samper E, Ramírez MJ, Creus A, Marcos R, Ortega JJ, Olivé T, Badell I, Blasco MA, Surrallés J. Breaks at telomeres and TRF2-independent end fusions in Fanconi anemia. Human Molecular Genetics. 11: 439-44. PMID 11854176 DOI: 10.1093/Hmg/11.4.439 |
0.311 |
|
| 2000 |
Chen JL, Blasco MA, Greider CW. Secondary structure of vertebrate telomerase RNA. Cell. 100: 503-14. PMID 10721988 DOI: 10.1016/S0092-8674(00)80687-X |
0.599 |
|
| 1999 |
Rudolph KL, Chang S, Lee HW, Blasco M, Gottlieb GJ, Greider C, DePinho RA. Longevity, stress response, and cancer in aging telomerase-deficient mice. Cell. 96: 701-12. PMID 10089885 DOI: 10.1016/S0092-8674(00)80580-2 |
0.59 |
|
| 1998 |
Lee HW, Blasco MA, Gottlieb GJ, Horner JW, Greider CW, DePinho RA. Essential role of mouse telomerase in highly proliferative organs. Nature. 392: 569-74. PMID 9560153 DOI: 10.1038/33345 |
0.6 |
|
| 1998 |
Hinkley CS, Blasco MA, Funk WD, Feng J, Villeponteau B, Greider CW, Herr W. The mouse telomerase RNA 5"-end lies just upstream of the telomerase template sequence. Nucleic Acids Research. 26: 532-6. PMID 9421511 DOI: 10.1093/Nar/26.2.532 |
0.593 |
|
| 1997 |
Blasco MA, Lee HW, Rizen M, Hanahan D, DePinho R, Greider CW. Mouse models for the study of telomerase. Ciba Foundation Symposium. 211: 160-70; discussion 1. PMID 9524757 |
0.641 |
|
| 1997 |
Blasco MA, Lee HW, Hande MP, Samper E, Lansdorp PM, DePinho RA, Greider CW. Telomere shortening and tumor formation by mouse cells lacking telomerase RNA. Cell. 91: 25-34. PMID 9335332 DOI: 10.1016/S0092-8674(01)80006-4 |
0.614 |
|
| 1996 |
Blasco MA, Rizen M, Greider CW, Hanahan D. Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis. Nature Genetics. 12: 200-4. PMID 8563761 DOI: 10.1038/Ng0296-200 |
0.613 |
|
| 1995 |
Blasco MA, Funk W, Villeponteau B, Greider CW. Functional characterization and developmental regulation of mouse telomerase RNA. Science (New York, N.Y.). 269: 1267-70. PMID 7544492 DOI: 10.1126/Science.7544492 |
0.631 |
|
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