Matthew Parsek - Publications

Affiliations: 
1999-2005 Northwestern University, Evanston, IL 
 2005-2010 University of Iowa, Iowa City, IA 
 2011- University of Washington, Seattle, Seattle, WA 
Area:
Microbiology, Biology
Website:
https://mcb-seattle.edu/faculty_profiles/parsek-matthew/

167 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Gheorghita AA, Wozniak DJ, Parsek MR, Howell PL. Pseudomonas aeruginosa biofilm exopolysaccharides: Assembly, function, and degradation. Fems Microbiology Reviews. PMID 37884397 DOI: 10.1093/femsre/fuad060  0.413
2023 Ferguson DL, Gloag ES, Parsek MR, Wozniak DJ. Extracellular DNA enhances biofilm integrity and mechanical properties of mucoid . Journal of Bacteriology. 205: e0023823. PMID 37791754 DOI: 10.1128/jb.00238-23  0.481
2023 Lichtenberg M, Coenye T, Parsek MR, Bjarnsholt T, Jakobsen TH. What's in a name? Characteristics of clinical biofilms. Fems Microbiology Reviews. 47. PMID 37656883 DOI: 10.1093/femsre/fuad050  0.472
2023 Kolodkin-Gal I, Parsek MR, Patrauchan MA. The roles of calcium signaling and calcium deposition in microbial multicellularity. Trends in Microbiology. PMID 37429751 DOI: 10.1016/j.tim.2023.06.005  0.312
2023 Razvi E, Whitfield GB, Reichhardt C, Dreifus JE, Willis AR, Gluscencova OB, Gloag ES, Awad TS, Rich JD, da Silva DP, Bond W, Le Mauff F, Sheppard DC, Hatton BD, Stoodley P, ... ... Parsek MR, et al. Glycoside hydrolase processing of the Pel polysaccharide alters biofilm biomechanics and Pseudomonas aeruginosa virulence. Npj Biofilms and Microbiomes. 9: 7. PMID 36732330 DOI: 10.1038/s41522-023-00375-7  0.493
2022 Morris AJ, Yau YCW, Park S, Eisha S, McDonald N, Parsek MR, Howell PL, Hoffman LR, Nguyen D, DiGiandomenico A, Rooney AM, Coburn B, Grana-Miraglia L, Wang P, Guttman DS, et al. Pseudomonas aeruginosa aggregation and Psl expression in sputum is associated with antibiotic eradication failure in children with cystic fibrosis. Scientific Reports. 12: 21444. PMID 36509824 DOI: 10.1038/s41598-022-25889-6  0.336
2022 Dreifus JE, O'Neal L, Jacobs HM, Subramanian AS, Howell PL, Wozniak DJ, Parsek MR. The Sia System and c-di-GMP Play a Crucial Role in Controlling Cell-Association of Psl in Planktonic P. aeruginosa. Journal of Bacteriology. 204: e0033522. PMID 36448788 DOI: 10.1128/jb.00335-22  0.454
2022 Le Mauff F, Razvi E, Reichhardt C, Sivarajah P, Parsek MR, Howell PL, Sheppard DC. Author Correction: The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine. Communications Biology. 5: 624. PMID 35750799 DOI: 10.1038/s42003-022-03567-7  0.208
2022 Le Mauff F, Razvi E, Reichhardt C, Sivarajah P, Parsek MR, Howell PL, Sheppard DC. The Pel polysaccharide is predominantly composed of a dimeric repeat of α-1,4 linked galactosamine and N-acetylgalactosamine. Communications Biology. 5: 502. PMID 35618750 DOI: 10.1038/s42003-022-03453-2  0.318
2022 O'Neal L, Baraquet C, Suo Z, Dreifus JE, Peng Y, Raivio TL, Wozniak DJ, Harwood CS, Parsek MR. The Wsp system of links surface sensing and cell envelope stress. Proceedings of the National Academy of Sciences of the United States of America. 119: e2117633119. PMID 35476526 DOI: 10.1073/pnas.2117633119  0.387
2022 Liu Y, Gloag ES, Hill PJ, Parsek MR, Wozniak DJ. Interbacterial Antagonism Mediated by a Released Polysaccharide. Journal of Bacteriology. 204: e0007622. PMID 35446119 DOI: 10.1128/jb.00076-22  0.404
2022 Jacobs HM, O'Neal L, Lopatto E, Wozniak DJ, Bjarnsholt T, Parsek MR. Mucoid Pseudomonas aeruginosa Can Produce Calcium-Gelled Biofilms Independent of the Matrix Components Psl and CdrA. Journal of Bacteriology. 204: e0056821. PMID 35416688 DOI: 10.1128/jb.00568-21  0.469
2022 Hu M, Xue Y, Li C, Lv M, Zhang L, Parsek MR, Lu G, Zhou X, Zhou J. Genomic and Functional Dissections of Dickeya zeae Shed Light on the Role of Type III Secretion System and Cell Wall-Degrading Enzymes to Host Range and Virulence. Microbiology Spectrum. e0159021. PMID 35107329 DOI: 10.1128/spectrum.01590-21  0.349
2022 Gheorghita AA, Wolfram F, Whitfield GB, Jacobs HM, Pfoh R, Wong SSY, Guitor AK, Goodyear MC, Berezuk AM, Khursigara CM, Parsek MR, Howell PL. The Pseudomonas aeruginosa homeostasis enzyme AlgL clears the periplasmic space of accumulated alginate during polymer biosynthesis. The Journal of Biological Chemistry. 101560. PMID 34990713 DOI: 10.1016/j.jbc.2021.101560  0.383
2021 Vasicek EM, O'Neal L, Parsek MR, Fitch J, White P, Gunn JS. L-Arabinose Transport and Metabolism in Influences Biofilm Formation. Frontiers in Cellular and Infection Microbiology. 11: 698146. PMID 34368016 DOI: 10.3389/fcimb.2021.698146  0.357
2021 Morris AJ, Jackson L, Cw Yau Y, Reichhardt C, Beaudoin T, Uwumarenogie S, Guttman KM, Lynne Howell P, Parsek MR, Hoffman LR, Nguyen D, DiGiandomenico A, Guttman DS, Wozniak DJ, Waters VJ. The role of Psl in the failure to eradicate Pseudomonas aeruginosa biofilms in children with cystic fibrosis. Npj Biofilms and Microbiomes. 7: 63. PMID 34349133 DOI: 10.1038/s41522-021-00234-3  0.4
2021 Almblad H, Randall TE, Liu F, Leblanc K, Groves RA, Kittichotirat W, Winsor GL, Fournier N, Au E, Groizeleau J, Rich JD, Lou Y, Granton E, Jennings LK, Singletary LA, ... ... Parsek MR, et al. Bacterial cyclic diguanylate signaling networks sense temperature. Nature Communications. 12: 1986. PMID 33790266 DOI: 10.1038/s41467-021-22176-2  0.406
2021 Armbruster CR, Parsek MR. Analysis of c-di-GMP High and Low Subpopulations Using Flow-assisted Cell Sorting (FACS) and Quantitative Reverse Transcriptase PCR (qRT-PCR). Bio-Protocol. 11: e3891. PMID 33732780 DOI: 10.21769/BioProtoc.3891  0.787
2021 Jennings LK, Dreifus JE, Reichhardt C, Storek KM, Secor PR, Wozniak DJ, Hisert KB, Parsek MR. Pseudomonas aeruginosa aggregates in cystic fibrosis sputum produce exopolysaccharides that likely impede current therapies. Cell Reports. 34: 108782. PMID 33626358 DOI: 10.1016/j.celrep.2021.108782  0.374
2020 Chen Y, Zhou J, Lv M, Liang Z, Parsek MR, Zhang LH. Systematic Analysis of c-di-GMP Signaling Mechanisms and Biological Functions in Dickeya zeae EC1. Mbio. 11. PMID 33262261 DOI: 10.1128/mBio.02993-20  0.381
2020 Harrison JJ, Parsek MR, Tseng BS. Bacterial Adaptation in Structured Environments: Lessons from Darwin's Finches. Trends in Microbiology. PMID 33187833 DOI: 10.1016/j.tim.2020.10.010  0.354
2020 Limqueco E, Passos Da Silva D, Reichhardt C, Su FY, Das D, Chen J, Srinivasan S, Convertine A, Skerrett SJ, Parsek MR, Stayton PS, Ratner DM. Mannose Conjugated Polymer Targeting Biofilms. Acs Infectious Diseases. PMID 33074651 DOI: 10.1021/acsinfecdis.0c00407  0.405
2020 Reichhardt C, Jacobs HM, Matwichuk M, Wong C, Wozniak DJ, Parsek MR. The versatile biofilm matrix protein CdrA promotes aggregation through different extracellular EPS interactions. Journal of Bacteriology. PMID 32661078 DOI: 10.1128/Jb.00216-20  0.438
2020 Marmont LS, Whitfield GB, Pfoh R, Williams RJ, Randall TE, Ostaszewski A, Razvi E, Groves RA, Robinson H, Nitz M, Parsek MR, Lewis IA, Whitney JC, Harrison J, Howell PL. PelX is a UDP-N-acetylglucosamine C4-epimerase involved in Pel polysaccharide-dependent biofilm formation. The Journal of Biological Chemistry. PMID 32601062 DOI: 10.1074/Jbc.Ra120.014555  0.462
2020 Harrison JJ, Almblad H, Irie Y, Wolter DJ, Eggleston HC, Randall TE, Kitzman JO, Stackhouse B, Emerson JC, Mcnamara S, Larsen TJ, Shendure J, Hoffman LR, Wozniak DJ, Parsek MR. Elevated exopolysaccharide levels in Pseudomonas aeruginosa flagellar mutants have implications for biofilm growth and chronic infections. Plos Genetics. 16: e1008848. PMID 32530919 DOI: 10.1371/Journal.Pgen.1008848  0.397
2020 Armbruster CR, Lee CK, Parker-Gilham J, de Anda J, Xia A, Zhao K, Murakami K, Tseng BS, Hoffman LR, Jin F, Harwood CS, Wong GC, Parsek MR. Correction: Heterogeneity in surface sensing suggests a division of labor in populations. Elife. 9. PMID 32452764 DOI: 10.7554/Elife.59154  0.747
2020 Lee CK, Vachier J, de Anda J, Zhao K, Baker AE, Bennett RR, Armbruster CR, Lewis KA, Tarnopol RL, Lomba CJ, Hogan DA, Parsek MR, O'Toole GA, Golestanian R, Wong GCL. Social Cooperativity of Bacteria during Reversible Surface Attachment in Young Biofilms: a Quantitative Comparison of Pseudomonas aeruginosa PA14 and PAO1. Mbio. 11. PMID 32098815 DOI: 10.1128/Mbio.02644-19  0.789
2020 Whitfield GB, Marmont LS, Ostaszewski A, Rich JD, Whitney JC, Parsek MR, Harrison JJ, Howell PL. Pel polysaccharide biosynthesis requires an inner membrane complex comprised of PelD, PelE, PelF and PelG. Journal of Bacteriology. PMID 31988082 DOI: 10.1128/Jb.00684-19  0.342
2019 Rupel K, Zupin L, Ottaviani G, Bertani I, Martinelli V, Porrelli D, Vodret S, Vuerich R, Passos da Silva D, Bussani R, Crovella S, Parsek M, Venturi V, Di Lenarda R, Biasotto M, et al. Blue laser light inhibits biofilm formation in vitro and in vivo by inducing oxidative stress. Npj Biofilms and Microbiomes. 5: 29. PMID 33028836 DOI: 10.1038/s41522-019-0102-9  0.382
2019 Rupel K, Zupin L, Ottaviani G, Bertani I, Martinelli V, Porrelli D, Vodret S, Vuerich R, Passos da Silva D, Bussani R, Crovella S, Parsek M, Venturi V, Di Lenarda R, Biasotto M, et al. Blue laser light inhibits biofilm formation in vitro and in vivo by inducing oxidative stress. Npj Biofilms and Microbiomes. 5: 29. PMID 31602310 DOI: 10.1038/s41522-019-0102-9  0.377
2019 Armbruster CR, Lee CK, Parker-Gilham J, de Anda J, Xia A, Zhao K, Tseng BS, Hoffman LR, Jin F, Harwood CS, Wong GCL, Parsek MR. Heterogeneity in surface sensing suggests a division of labor in populations. Elife. 8. PMID 31180327 DOI: 10.7554/Elife.45084  0.788
2019 Passos da Silva D, Matwichuk ML, Townsend DO, Reichhardt C, Lamba D, Wozniak DJ, Parsek MR. The Pseudomonas aeruginosa lectin LecB binds to the exopolysaccharide Psl and stabilizes the biofilm matrix. Nature Communications. 10: 2183. PMID 31097723 DOI: 10.1038/S41467-019-10201-4  0.448
2019 Reichhardt C, Parsek MR. Confocal Laser Scanning Microscopy for Analysis of Biofilm Architecture and Matrix Localization. Frontiers in Microbiology. 10: 677. PMID 31001240 DOI: 10.3389/fmicb.2019.00677  0.377
2019 Pestrak MJ, Baker P, Dellos-Nolan S, Hill PJ, da Silva DP, Silver H, Lacdao I, Raju D, Parsek MR, Wozniak DJ, Howell PL. Treatment with the glycoside hydrolase PslG combats wound infection by improving antibiotic efficacy and host innate immune activity. Antimicrobial Agents and Chemotherapy. PMID 30988141 DOI: 10.1128/Aac.00234-19  0.401
2018 Simon TD, Schaffzin JK, Stevenson CB, Willebrand K, Parsek M, Hoffman LR. Cerebrospinal Fluid Shunt Infection: Emerging Paradigms in Pathogenesis that Affect Prevention and Treatment. The Journal of Pediatrics. PMID 30528757 DOI: 10.1016/J.Jpeds.2018.11.026  0.345
2018 Reichhardt C, Wong C, Passos da Silva D, Wozniak DJ, Parsek MR. CdrA Interactions within the Pseudomonas aeruginosa Biofilm Matrix Safeguard It from Proteolysis and Promote Cellular Packing. Mbio. 9. PMID 30254118 DOI: 10.1128/Mbio.01376-18  0.408
2018 Dar HH, Tyurina YY, Mikulska-Ruminska K, Shrivastava I, Ting HC, Tyurin VA, Krieger J, St Croix CM, Watkins S, Bayir E, Mao G, Ambruster C, Kapralov A, Wang H, Parsek MH, et al. Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium. The Journal of Clinical Investigation. PMID 30198910 DOI: 10.1172/Jci99490  0.319
2018 Tseng BS, Reichhardt C, Merrihew GE, Araujo-Hernandez SA, Harrison JJ, MacCoss MJ, Parsek MR. A Biofilm Matrix-Associated Protease Inhibitor Protects Pseudomonas aeruginosa from Proteolytic Attack. Mbio. 9. PMID 29636440 DOI: 10.1128/Mbio.00543-18  0.393
2018 Armbruster CR, Parsek MR. New insight into the early stages of biofilm formation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29632199 DOI: 10.1073/pnas.1804084115  0.761
2018 Malhotra S, Limoli DH, English AE, Parsek MR, Wozniak DJ. Mixed Communities of Mucoid and NonmucoidExhibit Enhanced Resistance to Host Antimicrobials. Mbio. 9. PMID 29588399 DOI: 10.1128/Mbio.00275-18  0.339
2018 Pestrak MJ, Chaney SB, Eggleston HC, Dellos-Nolan S, Dixit S, Mathew-Steiner SS, Roy S, Parsek MR, Sen CK, Wozniak DJ. Pseudomonas aeruginosa rugose small-colony variants evade host clearance, are hyper-inflammatory, and persist in multiple host environments. Plos Pathogens. 14: e1006842. PMID 29394295 DOI: 10.1371/Journal.Ppat.1006842  0.366
2018 Reichhardt C, Wong C, da Silva DP, Wozniak DJ, Parsek MR. Both Cell-Associated and Secreted Forms of the P. aeruginosa Adhesin CDRA Promote Biofilm Formation Biophysical Journal. 114: 228a-229a. DOI: 10.1016/J.Bpj.2017.11.1272  0.428
2017 Passos da Silva D, Schofield MC, Parsek MR, Tseng BS. An Update on the Sociomicrobiology of Quorum Sensing in Gram-Negative Biofilm Development. Pathogens (Basel, Switzerland). 6. PMID 29065453 DOI: 10.3390/pathogens6040051  0.465
2017 Marmont LS, Whitfield GB, Rich JD, Yip P, Giesbrecht LB, Stremick CA, Whitney JC, Parsek MR, Harrison JJ, Howell PL. PelA and PelB form a modification and secretion complex essential for Pel polysaccharide-dependent biofilm formation in Pseudomonas aeruginosa. The Journal of Biological Chemistry. PMID 28972168 DOI: 10.1074/Jbc.M117.812842  0.395
2017 Snarr BD, Baker P, Bamford NC, Sato Y, Liu H, Lehoux M, Gravelat FN, Ostapska H, Baistrocchi SR, Cerone RP, Filler EE, Parsek MR, Filler SG, Howell PL, Sheppard DC. Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 28634301 DOI: 10.1073/Pnas.1702798114  0.438
2017 Amoh T, Murakami K, Kariyama R, Hori K, Viducic D, Hirota K, Igarashi J, Suga H, Parsek MR, Kumon H, Miyake Y. Effects of an autoinducer analogue on antibiotic tolerance in Pseudomonas aeruginosa. The Journal of Antimicrobial Chemotherapy. PMID 28510695 DOI: 10.1093/Jac/Dkx132  0.366
2017 Murakami K, Ono T, Viducic D, Somiya Y, Kariyama R, Hori K, Amoh T, Hirota K, Kumon H, Parsek MR, Miyake Y. The role of psl genes in antibiotic tolerance of adherent Pseudomonas aeruginosa. Antimicrobial Agents and Chemotherapy. PMID 28438927 DOI: 10.1128/AAC.02587-16  0.481
2017 Marmont LS, Rich JD, Whitney JC, Whitfield GB, Almblad H, Robinson H, Parsek MR, Harrison JJ, Howell PL. Oligomeric lipoprotein PelC guides Pel polysaccharide export across the outer membrane of Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences of the United States of America. PMID 28242707 DOI: 10.1073/Pnas.1613606114  0.412
2016 Baker P, Hill PJ, Snarr BD, Alnabelseya N, Pestrak MJ, Lee MJ, Jennings LK, Tam J, Melnyk RA, Parsek MR, Sheppard DC, Wozniak DJ, Howell PL. Exopolysaccharide biosynthetic glycoside hydrolases can be utilized to disrupt and prevent Pseudomonas aeruginosa biofilms. Science Advances. 2: e1501632. PMID 27386527 DOI: 10.1126/Sciadv.1501632  0.439
2016 Armbruster CR, Wolter DJ, Mishra M, Hayden HS, Radey MC, Merrihew G, MacCoss MJ, Burns J, Wozniak DJ, Parsek MR, Hoffman LR. Staphylococcus aureus Protein A Mediates Interspecies Interactions at the Cell Surface of Pseudomonas aeruginosa. Mbio. 7. PMID 27222468 DOI: 10.1128/Mbio.00538-16  0.794
2016 Tseng BS, Majerczyk CD, Passos da Silva D, Chandler JR, Greenberg EP, Parsek MR. Quorum sensing influences Burkholderia thailandensis biofilm development and matrix production. Journal of Bacteriology. PMID 27068594 DOI: 10.1128/Jb.00047-16  0.737
2016 Li X, Chopp DL, Russin WA, Brannon PT, Parsek MR, Packman AI. In situ biomineralization and particle deposition distinctively mediate biofilm susceptibility to chlorine. Applied and Environmental Microbiology. PMID 26944848 DOI: 10.1128/Aem.03954-15  0.39
2016 Parsek MR. Controlling the Connections of Cells to the Biofilm Matrix. Journal of Bacteriology. 198: 12-4. PMID 26527642 DOI: 10.1128/JB.00865-15  0.349
2015 Park JH, Jo Y, Jang SY, Kwon H, Irie Y, Parsek MR, Kim MH, Choi SH. Correction: The cabABC Operon Essential for Biofilm and Rugose Colony Development in Vibrio vulnificus. Plos Pathogens. 11: e1005252. PMID 26496079 DOI: 10.1371/Journal.Ppat.1005252  0.302
2015 Hmelo LR, Borlee BR, Almblad H, Love ME, Randall TE, Tseng BS, Lin C, Irie Y, Storek KM, Yang JJ, Siehnel RJ, Howell PL, Singh PK, Tolker-Nielsen T, Parsek MR, et al. Precision-engineering the Pseudomonas aeruginosa genome with two-step allelic exchange. Nature Protocols. 10: 1820-1841. PMID 26492139 DOI: 10.1038/Nprot.2015.115  0.302
2015 Park JH, Jo Y, Jang SY, Kwon H, Irie Y, Parsek MR, Kim MH, Choi SH. The cabABC Operon Essential for Biofilm and Rugose Colony Development in Vibrio vulnificus. Plos Pathogens. 11: e1005192. PMID 26406498 DOI: 10.1371/Journal.Ppat.1005192  0.455
2015 Jennings LK, Storek KM, Ledvina HE, Coulon C, Marmont LS, Sadovskaya I, Secor PR, Tseng BS, Scian M, Filloux A, Wozniak DJ, Howell PL, Parsek MR. Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix. Proceedings of the National Academy of Sciences of the United States of America. 112: 11353-8. PMID 26311845 DOI: 10.1073/Pnas.1503058112  0.423
2015 Cohen D, Mechold U, Nevenzal H, Yarmiyhu Y, Randall TE, Bay DC, Rich JD, Parsek MR, Kaever V, Harrison JJ, Banin E. Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences of the United States of America. 112: 11359-64. PMID 26305928 DOI: 10.1073/pnas.1421450112  0.388
2015 Li X, Chopp DL, Russin WA, Brannon PT, Parsek MR, Packman AI. Spatial patterns of carbonate biomineralization in biofilms. Applied and Environmental Microbiology. 81: 7403-10. PMID 26276112 DOI: 10.1128/Aem.01585-15  0.409
2015 Smalley NE, An D, Parsek MR, Chandler JR, Dandekar AA. Quorum Sensing Protects Pseudomonas aeruginosa against Cheating by Other Species in a Laboratory Coculture Model. Journal of Bacteriology. 197: 3154-9. PMID 26195596 DOI: 10.1128/Jb.00482-15  0.735
2015 Almblad H, Harrison JJ, Rybtke M, Groizeleau J, Givskov M, Parsek MR, Tolker-Nielsen T. Erratum for Almblad et al., The Cyclic AMP-Vfr Signaling Pathway in Pseudomonas aeruginosa Is Inhibited by Cyclic Di-GMP. Journal of Bacteriology. 197: 2731. PMID 26187287 DOI: 10.1128/JB.00493-15  0.251
2015 Amin SA, Hmelo LR, van Tol HM, Durham BP, Carlson LT, Heal KR, Morales RL, Berthiaume CT, Parker MS, Djunaedi B, Ingalls AE, Parsek MR, Moran MA, Armbrust EV. Interaction and signalling between a cosmopolitan phytoplankton and associated bacteria. Nature. 522: 98-101. PMID 26017307 DOI: 10.1038/Nature14488  0.366
2015 Almblad H, Harrison JJ, Rybtke M, Groizeleau J, Givskov M, Parsek MR, Tolker-Nielsen T. The Cyclic AMP-Vfr Signaling Pathway in Pseudomonas aeruginosa Is Inhibited by Cyclic Di-GMP. Journal of Bacteriology. 197: 2190-200. PMID 25897033 DOI: 10.1128/JB.00193-15  0.403
2015 Cohen D, Mechold U, Nevenzal H, Yarmiyhu Y, Randall TE, Bay DC, Rich JD, Parsek MR, Kaever V, Harrison JJ, Banin E. Oligoribonuclease is a central feature of cyclic diguanylate signaling in Pseudomonas aeruginosa Proceedings of the National Academy of Sciences of the United States of America. 112: 11359-11364. DOI: 10.1073/pnas.1421450112  0.269
2014 Doroshenko N, Tseng BS, Howlin RP, Deacon J, Wharton JA, Thurner PJ, Gilmore BF, Parsek MR, Stoodley P. Extracellular DNA impedes the transport of vancomycin in Staphylococcus epidermidis biofilms preexposed to subinhibitory concentrations of vancomycin. Antimicrobial Agents and Chemotherapy. 58: 7273-82. PMID 25267673 DOI: 10.1128/AAC.03132-14  0.729
2014 Wozniak DJ, Parsek MR. Surface-associated microbes continue to surprise us in their sophisticated strategies for assembling biofilm communities. F1000prime Reports. 6: 26. PMID 24860649 DOI: 10.12703/P6-26  0.446
2014 Irie Y, Parsek MR. LC/MS/MS-based quantitative assay for the secondary messenger molecule, c-di-GMP. Methods in Molecular Biology (Clifton, N.J.). 1149: 271-9. PMID 24818912 DOI: 10.1007/978-1-4939-0473-0_22  0.244
2014 Jones CJ, Newsom D, Kelly B, Irie Y, Jennings LK, Xu B, Limoli DH, Harrison JJ, Parsek MR, White P, Wozniak DJ. ChIP-Seq and RNA-Seq reveal an AmrZ-mediated mechanism for cyclic di-GMP synthesis and biofilm development by Pseudomonas aeruginosa. Plos Pathogens. 10: e1003984. PMID 24603766 DOI: 10.1371/Journal.Ppat.1003984  0.426
2013 Tseng BS, Zhang W, Harrison JJ, Quach TP, Song JL, Penterman J, Singh PK, Chopp DL, Packman AI, Parsek MR. The extracellular matrix protects Pseudomonas aeruginosa biofilms by limiting the penetration of tobramycin. Environmental Microbiology. 15: 2865-78. PMID 23751003 DOI: 10.1111/1462-2920.12155  0.47
2013 Zhao K, Tseng BS, Beckerman B, Jin F, Gibiansky ML, Harrison JJ, Luijten E, Parsek MR, Wong GC. Psl trails guide exploration and microcolony formation in Pseudomonas aeruginosa biofilms. Nature. 497: 388-91. PMID 23657259 DOI: 10.1038/Nature12155  0.696
2013 LaRock CN, Yu J, Horswill AR, Parsek MR, Minion FC. Transcriptome analysis of acyl-homoserine lactone-based quorum sensing regulation in Yersinia pestis [corrected]. Plos One. 8: e62337. PMID 23620823 DOI: 10.1371/Journal.Pone.0062337  0.346
2013 Wessel AK, Hmelo L, Parsek MR, Whiteley M. Going local: technologies for exploring bacterial microenvironments. Nature Reviews. Microbiology. 11: 337-48. PMID 23588251 DOI: 10.1038/Nrmicro3010  0.273
2013 Colvin KM, Alnabelseya N, Baker P, Whitney JC, Howell PL, Parsek MR. PelA deacetylase activity is required for Pel polysaccharide synthesis in Pseudomonas aeruginosa. Journal of Bacteriology. 195: 2329-39. PMID 23504011 DOI: 10.1128/JB.02150-12  0.421
2013 Wang S, Parsek MR, Wozniak DJ, Ma LZ. A spider web strategy of type IV pili-mediated migration to build a fibre-like Psl polysaccharide matrix in Pseudomonas aeruginosa biofilms. Environmental Microbiology. 15: 2238-53. PMID 23425591 DOI: 10.1111/1462-2920.12095  0.455
2013 LaRock CN, Yu J, Horswill AR, Parsek MR, Minion FC. Correction: Transcriptome Analysis of Acetyl-Homoserine Lactone-Based Quorum Sensing Regulation in Yersinia pestis Plos One. 8. DOI: 10.1371/Annotation/3F0E8E82-1Db8-45Fe-A700-C64Ede3E3C61  0.28
2012 Irie Y, Borlee BR, O'Connor JR, Hill PJ, Harwood CS, Wozniak DJ, Parsek MR. Self-produced exopolysaccharide is a signal that stimulates biofilm formation in Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences of the United States of America. 109: 20632-6. PMID 23175784 DOI: 10.1073/Pnas.1217993109  0.492
2012 Whitney JC, Colvin KM, Marmont LS, Robinson H, Parsek MR, Howell PL. Structure of the cytoplasmic region of PelD, a degenerate diguanylate cyclase receptor that regulates exopolysaccharide production in Pseudomonas aeruginosa. The Journal of Biological Chemistry. 287: 23582-93. PMID 22605337 DOI: 10.1074/Jbc.M112.375378  0.369
2012 Rybtke MT, Borlee BR, Murakami K, Irie Y, Hentzer M, Nielsen TE, Givskov M, Parsek MR, Tolker-Nielsen T. Fluorescence-based reporter for gauging cyclic di-GMP levels in Pseudomonas aeruginosa. Applied and Environmental Microbiology. 78: 5060-9. PMID 22582064 DOI: 10.1128/Aem.00414-12  0.437
2012 Baraquet C, Murakami K, Parsek MR, Harwood CS. The FleQ protein from Pseudomonas aeruginosa functions as both a repressor and an activator to control gene expression from the pel operon promoter in response to c-di-GMP. Nucleic Acids Research. 40: 7207-18. PMID 22581773 DOI: 10.1093/Nar/Gks384  0.376
2012 Ma L, Wang J, Wang S, Anderson EM, Lam JS, Parsek MR, Wozniak DJ. Synthesis of multiple Pseudomonas aeruginosa biofilm matrix exopolysaccharides is post-transcriptionally regulated. Environmental Microbiology. 14: 1995-2005. PMID 22513190 DOI: 10.1111/J.1462-2920.2012.02753.X  0.406
2012 Ma L, Wang S, Wang D, Parsek MR, Wozniak DJ. The roles of biofilm matrix polysaccharide Psl in mucoid Pseudomonas aeruginosa biofilms. Fems Immunology and Medical Microbiology. 65: 377-80. PMID 22309106 DOI: 10.1111/J.1574-695X.2012.00934.X  0.471
2012 Marmont LS, Whitney JC, Robinson H, Colvin KM, Parsek MR, Howell PL. Expression, purification, crystallization and preliminary X-ray analysis of Pseudomonas aeruginosa PelD. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 181-4. PMID 22297994 DOI: 10.1107/S1744309111052109  0.243
2012 Colvin KM, Irie Y, Tart CS, Urbano R, Whitney JC, Ryder C, Howell PL, Wozniak DJ, Parsek MR. The Pel and Psl polysaccharides provide Pseudomonas aeruginosa structural redundancy within the biofilm matrix. Environmental Microbiology. 14: 1913-28. PMID 22176658 DOI: 10.1111/J.1462-2920.2011.02657.X  0.431
2012 Mishra M, Byrd MS, Sergeant S, Azad AK, Parsek MR, McPhail L, Schlesinger LS, Wozniak DJ. Pseudomonas aeruginosa Psl polysaccharide reduces neutrophil phagocytosis and the oxidative response by limiting complement-mediated opsonization. Cellular Microbiology. 14: 95-106. PMID 21951860 DOI: 10.1111/J.1462-5822.2011.01704.X  0.366
2012 Parsek M. Reviews and Resources Microbe Magazine. 7: 288-288. DOI: 10.1128/Microbe.7.288.1  0.288
2011 Alhede M, Kragh KN, Qvortrup K, Allesen-Holm M, van Gennip M, Christensen LD, Jensen PØ, Nielsen AK, Parsek M, Wozniak D, Molin S, Tolker-Nielsen T, Høiby N, Givskov M, Bjarnsholt T. Phenotypes of non-attached Pseudomonas aeruginosa aggregates resemble surface attached biofilm. Plos One. 6: e27943. PMID 22132176 DOI: 10.1371/Journal.Pone.0027943  0.452
2011 Shrout JD, Tolker-Nielsen T, Givskov M, Parsek MR. The contribution of cell-cell signaling and motility to bacterial biofilm formation. Mrs Bulletin / Materials Research Society. 36: 367-373. PMID 22053126 DOI: 10.1557/Mrs.2011.67  0.523
2011 Byrd MS, Pang B, Hong W, Waligora EA, Juneau RA, Armbruster CE, Weimer KE, Murrah K, Mann EE, Lu H, Sprinkle A, Parsek MR, Kock ND, Wozniak DJ, Swords WE. Direct evaluation of Pseudomonas aeruginosa biofilm mediators in a chronic infection model. Infection and Immunity. 79: 3087-95. PMID 21646454 DOI: 10.1128/Iai.00057-11  0.465
2011 Colvin KM, Gordon VD, Murakami K, Borlee BR, Wozniak DJ, Wong GC, Parsek MR. The pel polysaccharide can serve a structural and protective role in the biofilm matrix of Pseudomonas aeruginosa. Plos Pathogens. 7: e1001264. PMID 21298031 DOI: 10.1371/Journal.Ppat.1001264  0.707
2011 Peterson SB, Irie Y, Borlee BR, Murakami K, Harrison JJ, Colvin KM, Parsek MR. Different methods for culturing biofilms in vitro Biofilm Infections. 251-266. DOI: 10.1007/978-1-4419-6084-9_15  0.332
2010 Connell JL, Wessel AK, Parsek MR, Ellington AD, Whiteley M, Shear JB. Probing prokaryotic social behaviors with bacterial "lobster traps". Mbio. 1. PMID 21060734 DOI: 10.1128/Mbio.00202-10  0.428
2010 Irie Y, Starkey M, Edwards AN, Wozniak DJ, Romeo T, Parsek MR. Pseudomonas aeruginosa biofilm matrix polysaccharide Psl is regulated transcriptionally by RpoS and post-transcriptionally by RsmA. Molecular Microbiology. 78: 158-72. PMID 20735777 DOI: 10.1111/J.1365-2958.2010.07320.X  0.667
2010 Häussler S, Parsek MR. Biofilms 2009: new perspectives at the heart of surface-associated microbial communities. Journal of Bacteriology. 192: 2941-9. PMID 20382760 DOI: 10.1128/JB.00332-10  0.352
2010 Siehnel R, Traxler B, An DD, Parsek MR, Schaefer AL, Singh PK. A unique regulator controls the activation threshold of quorum-regulated genes in Pseudomonas aeruginosa. Proceedings of the National Academy of Sciences of the United States of America. 107: 7916-21. PMID 20378835 DOI: 10.1073/Pnas.0908511107  0.774
2010 Borlee BR, Goldman AD, Murakami K, Samudrala R, Wozniak DJ, Parsek MR. Pseudomonas aeruginosa uses a cyclic-di-GMP-regulated adhesin to reinforce the biofilm extracellular matrix. Molecular Microbiology. 75: 827-42. PMID 20088866 DOI: 10.1111/J.1365-2958.2009.06991.X  0.483
2010 Hibbing ME, Fuqua C, Parsek MR, Peterson SB. Bacterial competition: surviving and thriving in the microbial jungle. Nature Reviews. Microbiology. 8: 15-25. PMID 19946288 DOI: 10.1038/Nrmicro2259  0.361
2009 Byrd MS, Sadovskaya I, Vinogradov E, Lu H, Sprinkle AB, Richardson SH, Ma L, Ralston B, Parsek MR, Anderson EM, Lam JS, Wozniak DJ. Genetic and biochemical analyses of the Pseudomonas aeruginosa Psl exopolysaccharide reveal overlapping roles for polysaccharide synthesis enzymes in Psl and LPS production. Molecular Microbiology. 73: 622-38. PMID 19659934 DOI: 10.1111/J.1365-2958.2009.06795.X  0.408
2009 Alhede M, Bjarnsholt T, Jensen P, Phipps RK, Moser C, Christophersen L, Christensen LD, van Gennip M, Parsek M, Høiby N, Rasmussen TB, Givskov M. Pseudomonas aeruginosa recognizes and responds aggressively to the presence of polymorphonuclear leukocytes Microbiology. 155: 3500-3508. PMID 19643762 DOI: 10.1099/mic.0.031443-0  0.451
2009 Harrison JJ, Tremaroli V, Stan MA, Chan CS, Vacchi-Suzzi C, Heyne BJ, Parsek MR, Ceri H, Turner RJ. Chromosomal antioxidant genes have metal ion-specific roles as determinants of bacterial metal tolerance. Environmental Microbiology. 11: 2491-509. PMID 19555372 DOI: 10.1111/J.1462-2920.2009.01973.X  0.251
2009 Duerkop BA, Varga J, Chandler JR, Peterson SB, Herman JP, Churchill ME, Parsek MR, Nierman WC, Greenberg EP. Quorum-sensing control of antibiotic synthesis in Burkholderia thailandensis. Journal of Bacteriology. 191: 3909-18. PMID 19376863 DOI: 10.1128/Jb.00200-09  0.696
2009 Starkey M, Hickman JH, Ma L, Zhang N, De Long S, Hinz A, Palacios S, Manoil C, Kirisits MJ, Starner TD, Wozniak DJ, Harwood CS, Parsek MR. Pseudomonas aeruginosa rugose small-colony variants have adaptations that likely promote persistence in the cystic fibrosis lung. Journal of Bacteriology. 191: 3492-503. PMID 19329647 DOI: 10.1128/Jb.00119-09  0.703
2009 Ma L, Conover M, Lu H, Parsek MR, Bayles K, Wozniak DJ. Assembly and development of the Pseudomonas aeruginosa biofilm matrix. Plos Pathogens. 5: e1000354. PMID 19325879 DOI: 10.1371/Journal.Ppat.1000354  0.442
2008 Parsek MR, Tolker-Nielsen T. Pattern formation in Pseudomonas aeruginosa biofilms. Current Opinion in Microbiology. 11: 560-6. PMID 18935979 DOI: 10.1016/j.mib.2008.09.015  0.463
2008 Smalyukh II, Butler J, Shrout JD, Parsek MR, Wong GC. Elasticity-mediated nematiclike bacterial organization in model extracellular DNA matrix. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 78: 030701. PMID 18850984 DOI: 10.1103/Physreve.78.030701  0.628
2008 Stoltz DA, Ozer EA, Taft PJ, Barry M, Liu L, Kiss PJ, Moninger TO, Parsek MR, Zabner J. Drosophila are protected from Pseudomonas aeruginosa lethality by transgenic expression of paraoxonase-1. The Journal of Clinical Investigation. 118: 3123-31. PMID 18704198 DOI: 10.1172/Jci35147  0.422
2008 Irie Y, Parsek MR. Quorum sensing and microbial biofilms Current Topics in Microbiology and Immunology. 322: 67-84. PMID 18453272 DOI: 10.1007/978-3-540-75418-3_4  0.406
2008 Starner TD, Shrout JD, Parsek MR, Appelbaum PC, Kim G. Subinhibitory concentrations of azithromycin decrease nontypeable Haemophilus influenzae biofilm formation and Diminish established biofilms. Antimicrobial Agents and Chemotherapy. 52: 137-45. PMID 17954687 DOI: 10.1128/Aac.00607-07  0.43
2007 Parsek MR. Microbiology: bilingual bacteria. Nature. 450: 805-7. PMID 18063996 DOI: 10.1038/450805a  0.396
2007 Kirisits MJ, Margolis JJ, Purevdorj-Gage BL, Vaughan B, Chopp DL, Stoodley P, Parsek MR. Influence of the hydrodynamic environment on quorum sensing in Pseudomonas aeruginosa biofilms. Journal of Bacteriology. 189: 8357-60. PMID 17704224 DOI: 10.1128/Jb.01040-07  0.43
2007 Ma L, Lu H, Sprinkle A, Parsek MR, Wozniak DJ. Pseudomonas aeruginosa Psl is a galactose- and mannose-rich exopolysaccharide. Journal of Bacteriology. 189: 8353-6. PMID 17631634 DOI: 10.1128/Jb.00620-07  0.356
2007 An D, Parsek MR. The promise and peril of transcriptional profiling in biofilm communities. Current Opinion in Microbiology. 10: 292-6. PMID 17573234 DOI: 10.1016/J.Mib.2007.05.011  0.639
2007 Stoltz DA, Ozer EA, Ng CJ, Yu JM, Reddy ST, Lusis AJ, Bourquard N, Parsek MR, Zabner J, Shih DM. Paraoxonase-2 deficiency enhances Pseudomonas aeruginosa quorum sensing in murine tracheal epithelia. American Journal of Physiology. Lung Cellular and Molecular Physiology. 292: L852-60. PMID 17122353 DOI: 10.1152/Ajplung.00370.2006  0.384
2007 Horswill AR, Stoodley P, Stewart PS, Parsek MR. The effect of the chemical, biological, and physical environment on quorum sensing in structured microbial communities. Analytical and Bioanalytical Chemistry. 387: 371-80. PMID 17047948 DOI: 10.1007/S00216-006-0720-Y  0.31
2006 Shrout JD, Chopp DL, Just CL, Hentzer M, Givskov M, Parsek MR. The impact of quorum sensing and swarming motility on Pseudomonas aeruginosa biofilm formation is nutritionally conditional. Molecular Microbiology. 62: 1264-77. PMID 17059568 DOI: 10.1111/J.1365-2958.2006.05421.X  0.453
2006 Kirisits MJ, Parsek MR. Does Pseudomonas aeruginosa use intercellular signalling to build biofilm communities? Cellular Microbiology. 8: 1841-9. PMID 17026480 DOI: 10.1111/J.1462-5822.2006.00817.X  0.455
2006 Teitzel GM, Geddie A, De Long SK, Kirisits MJ, Whiteley M, Parsek MR. Survival and growth in the presence of elevated copper: transcriptional profiling of copper-stressed Pseudomonas aeruginosa. Journal of Bacteriology. 188: 7242-56. PMID 17015663 DOI: 10.1128/Jb.00837-06  0.747
2006 Ma L, Jackson KD, Landry RM, Parsek MR, Wozniak DJ. Analysis of Pseudomonas aeruginosa conditional psl variants reveals roles for the psl polysaccharide in adhesion and maintaining biofilm structure postattachment. Journal of Bacteriology. 188: 8213-21. PMID 16980452 DOI: 10.1128/Jb.01202-06  0.484
2006 An D, Danhorn T, Fuqua C, Parsek MR. Quorum sensing and motility mediate interactions between Pseudomonas aeruginosa and Agrobacterium tumefaciens in biofilm cocultures. Proceedings of the National Academy of Sciences of the United States of America. 103: 3828-33. PMID 16537456 DOI: 10.1073/Pnas.0511323103  0.645
2006 Landry RM, An D, Hupp JT, Singh PK, Parsek MR. Mucin-Pseudomonas aeruginosa interactions promote biofilm formation and antibiotic resistance. Molecular Microbiology. 59: 142-51. PMID 16359324 DOI: 10.1111/J.1365-2958.2005.04941.X  0.671
2005 Ramey BE, Parsek MR. Growing and analyzing biofilms in fermenters. Current Protocols in Microbiology. Unit 1B.3. PMID 18770546 DOI: 10.1002/9780471729259.mc01b03s00  0.409
2005 Leid JG, Willson CJ, Shirtliff ME, Hassett DJ, Parsek MR, Jeffers AK. The exopolysaccharide alginate protects Pseudomonas aeruginosa biofilm bacteria from IFN-gamma-mediated macrophage killing. Journal of Immunology (Baltimore, Md. : 1950). 175: 7512-8. PMID 16301659 DOI: 10.4049/Jimmunol.175.11.7512  0.468
2005 Kirisits MJ, Prost L, Starkey M, Parsek MR. Characterization of colony morphology variants isolated from Pseudomonas aeruginosa biofilms. Applied and Environmental Microbiology. 71: 4809-21. PMID 16085879 DOI: 10.1128/Aem.71.8.4809-4821.2005  0.672
2005 Parsek MR, Greenberg EP. Sociomicrobiology: the connections between quorum sensing and biofilms. Trends in Microbiology. 13: 27-33. PMID 15639629 DOI: 10.1016/j.tim.2004.11.007  0.527
2004 Danhorn T, Hentzer M, Givskov M, Parsek MR, Fuqua C. Phosphorus limitation enhances biofilm formation of the plant pathogen Agrobacterium tumefaciens through the PhoR-PhoB regulatory system. Journal of Bacteriology. 186: 4492-501. PMID 15231781 DOI: 10.1128/Jb.186.14.4492-4501.2004  0.463
2004 Jackson KD, Starkey M, Kremer S, Parsek MR, Wozniak DJ. Identification of psl, a locus encoding a potential exopolysaccharide that is essential for Pseudomonas aeruginosa PAO1 biofilm formation. Journal of Bacteriology. 186: 4466-75. PMID 15231778 DOI: 10.1128/Jb.186.14.4466-4475.2004  0.713
2004 Parsek MR, Fuqua C. Biofilms 2003: emerging themes and challenges in studies of surface-associated microbial life. Journal of Bacteriology. 186: 4427-40. PMID 15231774 DOI: 10.1128/Jb.186.14.4427-4440.2004  0.425
2003 Chopp DL, Kirisits MJ, Moran B, Parsek MR. The dependence of quorum sensing on the depth of a growing biofilm. Bulletin of Mathematical Biology. 65: 1053-79. PMID 14607288 DOI: 10.1016/S0092-8240(03)00057-0  0.442
2003 Parsek MR, Singh PK. Bacterial biofilms: an emerging link to disease pathogenesis. Annual Review of Microbiology. 57: 677-701. PMID 14527295 DOI: 10.1146/annurev.micro.57.030502.090720  0.437
2003 Riesbeck CK, Qiu L, Weusijana BK, Walsh JT, Parsek M. Learning technologies to foster critical reasoning. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 22: 55-7, 117. PMID 14515693 DOI: 10.1109/Memb.2003.1237502  0.313
2003 Wozniak DJ, Wyckoff TJ, Starkey M, Keyser R, Azadi P, O'Toole GA, Parsek MR. Alginate is not a significant component of the extracellular polysaccharide matrix of PA14 and PAO1 Pseudomonas aeruginosa biofilms. Proceedings of the National Academy of Sciences of the United States of America. 100: 7907-12. PMID 12810959 DOI: 10.1073/Pnas.1231792100  0.699
2003 Teitzel GM, Parsek MR. Heavy metal resistance of biofilm and planktonic Pseudomonas aeruginosa. Applied and Environmental Microbiology. 69: 2313-20. PMID 12676715 DOI: 10.1128/AEM.69.4.2313-2320.2003  0.763
2003 McKenna A, Parsek M, Birol G, Riesbeck C. Cross-disciplinary approach to developing challenge-based instruction Asee Annual Conference Proceedings. 8775-8788.  0.209
2002 Chopp DL, Kirisits MJ, Moran B, Parsek MR. A mathematical model of quorum sensing in a growing bacterial biofilm. Journal of Industrial Microbiology & Biotechnology. 29: 339-46. PMID 12483476 DOI: 10.1038/Sj.Jim.7000316  0.434
2002 Yoon SS, Hennigan RF, Hilliard GM, Ochsner UA, Parvatiyar K, Kamani MC, Allen HL, DeKievit TR, Gardner PR, Schwab U, Rowe JJ, Iglewski BH, McDermott TR, Mason RP, Wozniak DJ, ... ... Parsek MR, et al. Pseudomonas aeruginosa anaerobic respiration in biofilms: relationships to cystic fibrosis pathogenesis. Developmental Cell. 3: 593-603. PMID 12408810 DOI: 10.1016/S1534-5807(02)00295-2  0.427
2002 Singh PK, Parsek MR, Greenberg EP, Welsh MJ. A component of innate immunity prevents bacterial biofilm development. Nature. 417: 552-5. PMID 12037568 DOI: 10.1038/417552A  0.617
2002 Heydorn A, Ersbøll B, Kato J, Hentzer M, Parsek MR, Tolker-Nielsen T, Givskov M, Molin S. Statistical analysis of Pseudomonas aeruginosa biofilm development: impact of mutations in genes involved in twitching motility, cell-to-cell signaling, and stationary-phase sigma factor expression. Applied and Environmental Microbiology. 68: 2008-17. PMID 11916724 DOI: 10.1128/AEM.68.4.2008-2017.2002  0.399
2002 Hentzer M, Riedel K, Rasmussen TB, Heydorn A, Andersen JB, Parsek MR, Rice SA, Eberl L, Molin S, Høiby N, Kjelleberg S, Givskov M. Inhibition of quorum sensing in Pseudomonas aeruginosa biofilm bacteria by a halogenated furanone compound. Microbiology (Reading, England). 148: 87-102. PMID 11782502 DOI: 10.1099/00221287-148-1-87  0.462
2002 Hentzer M, Givskov M, Parsek MR. Targeting quorum sensing for treatment of chronic bacterial biofilm infections Laboratory Medicine. 33: 295-306. DOI: 10.1309/EYEV-WT6T-GKHE-C8LM  0.418
2002 Singh P, Parsek M. Lactoferrine : un rôle antibactérien dans les infections chroniques Revue FrançAise Des Laboratoires. 2002: 16-17. DOI: 10.1016/s0338-9898(02)80299-2  0.204
2002 McKenna A, Walsh JT, Parsek M, Birol G. Assessing challenge-based instruction in biomedical engineering Asee Annual Conference Proceedings. 12783-12795.  0.2
2001 Fuqua C, Parsek MR, Greenberg EP. Regulation of gene expression by cell-to-cell communication: Acyl-homoserine lactone quorum sensing Annual Review of Genetics. 35: 439-468. PMID 11700290 DOI: 10.1146/Annurev.Genet.35.102401.090913  0.569
2001 Whiteley M, Bangera MG, Bumgarner RE, Parsek MR, Teitzel GM, Lory S, Greenberg EP. Gene expression in Pseudomonas aeruginosa biofilms. Nature. 413: 860-4. PMID 11677611 DOI: 10.1038/35101627  0.816
2001 Hentzer M, Teitzel GM, Balzer GJ, Heydorn A, Molin S, Givskov M, Parsek MR. Alginate overproduction affects Pseudomonas aeruginosa biofilm structure and function. Journal of Bacteriology. 183: 5395-401. PMID 11514525 DOI: 10.1128/JB.183.18.5395-5401.2001  0.799
2001 Schaefer AL, Greenberg EP, Parsek MR. Acylated homoserine lactone detection in Pseudomonas aeruginosa biofilms by radiolabel assay Methods in Enzymology. 336: 41-47. PMID 11398416 DOI: 10.1016/S0076-6879(01)36576-X  0.781
2000 Singh PK, Schaefer AL, Parsek MR, Moninger TO, Welsh MJ, Greenberg EP. Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms. Nature. 407: 762-4. PMID 11048725 DOI: 10.1038/35037627  0.774
2000 Heydorn A, Ersboll BK, Hentzer M, Parsek MR, Givskov M, Molin S. Experimental reproducibility in flow-chamber biofilms Microbiology. 146: 2409-2415. PMID 11021917  0.369
2000 Parsek MR, Greenberg EP. Acyl-homoserine lactone quorum sensing in Gram-negative bacteria: A signaling mechanism involved in associations with higher organisms Proceedings of the National Academy of Sciences of the United States of America. 97: 8789-8793. PMID 10922036 DOI: 10.1073/pnas.97.16.8789  0.574
2000 Whiteley M, Parsek MR, Greenberg EP. Regulation of quorum sensing by RpoS in Pseudomonas aeruginosa Journal of Bacteriology. 182: 4356-4360. PMID 10894749 DOI: 10.1128/Jb.182.15.4356-4360.2000  0.552
2000 Schaefer AL, Hanzelka BL, Parsek MR, Greenberg EP. Detection, purification, and structural elucidation of the acylhomoserine lactone inducer of Vibrio fischeri luminescence and other related molecules Methods in Enzymology. 305: 288-301. PMID 10812608 DOI: 10.1016/S0076-6879(00)05495-1  0.699
1999 Parsek MR, Greenberg EP. Quorum sensing signals in development of Pseudomonas aeruginosa biofilms Methods in Enzymology. 310: 43-55. PMID 10547781 DOI: 10.1016/S0076-6879(99)10005-3  0.62
1999 Hanzelka BL, Parsek MR, Val DL, Dunlap PV, Cronan JE, Greenberg EP. Acylhomoserine lactone synthase activity of the Vibrio fischeri AinS protein Journal of Bacteriology. 181: 5766-5770. PMID 10482519 DOI: 10.1128/Jb.181.18.5766-5770.1999  0.475
1999 Parsek MR, Val DL, Hanzelka BL, Cronan JE, Greenberg EP. Acyl homoserine-lactone quorum-sensing signal generation Proceedings of the National Academy of Sciences of the United States of America. 96: 4360-4365. PMID 10200267 DOI: 10.1073/Pnas.96.8.4360  0.536
1999 Hanzelka BL, Parsek MR, Val DL, Dunlap PV, Cronan JE, Greenberg EP. Acylhomoserine Lactone Synthase Activity of the Vibrio fischeri AinS Protein Journal of Bacteriology. 181: 5766-5770. DOI: 10.1128/jb.181.18.5766-5770.1999  0.28
1998 Chugani SA, Parsek MR, Chakrabarty AM. Transcriptional repression mediated by LysR-type regulator CatR bound at multiple binding sites Journal of Bacteriology. 180: 2367-2372. PMID 9573187 DOI: 10.1128/Jb.180.9.2367-2372.1998  0.641
1998 Davies DG, Parsek MR, Pearson JP, Iglewski BH, Costerton JW, Greenberg EP. The involvement of cell-to-cell signals in the development of a bacterial biofilm Science. 280: 295-298. PMID 9535661 DOI: 10.1126/Science.280.5361.295  0.617
1997 Parsek MR, Schaefer AL, Greenberg EP. Analysis of random and site-directed mutations in rhII, a Pseudomonas aeruginosa gene encoding an acylhomoserine lactone synthesis Molecular Microbiology. 26: 301-310. PMID 9383155 DOI: 10.1046/J.1365-2958.1997.5741935.X  0.736
1997 Hanzelka BL, Stevens AM, Parsek MR, Crone TJ, Greenberg EP. Mutational analysis of the Vibrio fischeri LuxI polypeptide: critical regions of an autoinducer synthase. Journal of Bacteriology. 179: 4882-7. PMID 9244278  0.489
1997 Mcfall SM, Parsek MR, Chakrabarty AM. 2-Chloromuconate and Clcr-mediated activation of the clcABD operon: In vitro transcriptional and DNase I footprint analyses Journal of Bacteriology. 179: 3655-3663. PMID 9171413 DOI: 10.1128/Jb.179.11.3655-3663.1997  0.663
1997 Chugani SA, Parsek MR, Hershberger CD, Murakami K, Ishihama A, Chakrabarty AM. Activation of the catBCA promoter: Probing the interaction of CatR and RNA polymerase through in vitro transcription Journal of Bacteriology. 179: 2221-2227. PMID 9079907 DOI: 10.1128/Jb.179.7.2221-2227.1997  0.653
1995 Hershberger CD, Ye RW, Parsek MR, Xie ZD, Chakrabarty AM. The algT (algU) gene of Pseudomonas aeruginosa, a key regulator involved in alginate biosynthesis, encodes an alternative δ factor (σE) Proceedings of the National Academy of Sciences of the United States of America. 92: 7941-7945. PMID 7644517 DOI: 10.1073/pnas.92.17.7941  0.684
1995 Parsek MR, Kivisaar M, Chakrabarty AM. Differential DNA bending introduced by the Pseudomonas putida LysR-type regulator, CatR, at the plasmid-borne pheBA and chromosomal catBC promoters Molecular Microbiology. 15: 819-828. PMID 7596284 DOI: 10.1111/J.1365-2958.1995.Tb02352.X  0.641
1995 Parsek MR, McFall SM, Chakrabarty AM. Microbial degradation of toxic, environmental pollutants: Ecological and evolutionary considerations International Biodeterioration and Biodegradation. 35: 175-188. DOI: 10.1016/0964-8305(95)00032-Z  0.621
1994 Parsek MR, Ye RW, Pun P, Chakrabarty AM. Critical nucleotides in the interaction of a LysR-type regulator with its target promoter region: catBC promoter activation by CatR Journal of Biological Chemistry. 269: 11279-11284. PMID 8157659  0.636
1994 Coco WM, Parsek MR, Chakrabarty AM. Purification of the LysR family regulator, ClcR, and its interaction with the Pseudomonas putida clcABD chlorocatechol operon promoter Journal of Bacteriology. 176: 5530-5533. PMID 8071232 DOI: 10.1128/Jb.176.17.5530-5533.1994  0.663
1994 Parsek MR, Mcfall SM, Shinabarger DL, Chakrabarty AM. Interaction of two LysR-type regulatory proteins CatR and ClcR with heterologous promoters: Functional and evolutionary implications Proceedings of the National Academy of Sciences of the United States of America. 91: 12393-12397. PMID 7809047 DOI: 10.1073/pnas.91.26.12393  0.691
1992 Parsek MR, Shinabarger DL, Rothmel RK, Chakrabarty AM. Roles of CatR and cis,cis-muconate in activation of the catBC operon, which is involved in benzoate degradation in Pseudomonas putida Journal of Bacteriology. 174: 7798-7806. PMID 1447146 DOI: 10.1128/Jb.174.23.7798-7806.1992  0.632
1991 Rothmel RK, Shinabarger DL, Parsek MR, Aldrich TL, Chakrabarty AM. Functional analysis of the Pseudomonas putida regulatory protein CatR: Transcriptional studies and determination of the CatR DNA-binding site by hydroxyl-radical footprinting Journal of Bacteriology. 173: 4717-4724. PMID 1649820 DOI: 10.1128/Jb.173.15.4717-4724.1991  0.651
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