Year |
Citation |
Score |
2020 |
Mo J, Anastasaki C, Chen Z, Shipman T, Papke JB, Yin KY, Gutmann DH, Le LQ. Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins. The Journal of Clinical Investigation. PMID 33108355 DOI: 10.1172/JCI139807 |
0.311 |
|
2020 |
Brosseau JP, Liao CP, Le LQ. Translating current basic research into future therapies for neurofibromatosis type 1. British Journal of Cancer. PMID 32439933 DOI: 10.1038/S41416-020-0903-X |
0.391 |
|
2020 |
Chen Z, Mo J, Brosseau J, Shipman T, Wang Y, Liao C, Cooper JM, Allaway RJ, Gosline SJC, Guinney J, Carroll TJ, Le LQ. Abstract B23: A novel model of neurofibroma that deciphers its developmental origin and susceptibility to modification by the Hippo pathway Molecular Cancer Research. 18. DOI: 10.1158/1557-3125.Hippo19-B23 |
0.395 |
|
2019 |
Le LQ, Cooper JM, Patel AJ, Chen Z, Liao CP, Chen K, Wang Y, Mo J. Overcoming BET inhibitor resistance in malignant peripheral nerve sheath tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30796033 DOI: 10.1158/1078-0432.Ccr-18-2437 |
0.308 |
|
2018 |
Brosseau JP, Liao CP, Wang Y, Ramani V, Vandergriff T, Lee M, Patel A, Ariizumi K, Le LQ. NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation. Nature Communications. 9: 5014. PMID 30479396 DOI: 10.1038/S41467-018-07452-Y |
0.354 |
|
2018 |
Chen Z, Mo J, Brosseau JP, Shipman T, Wang Y, Liao CP, Cooper JM, Allaway RJ, Gosline SJC, Guinney J, Carroll TJ, Le LQ. Spatiotemporal loss of NF1 in Schwann cell lineage leads to different types of cutaneous neurofibroma susceptible to modification by the Hippo pathway. Cancer Discovery. PMID 30348677 DOI: 10.1158/2159-8290.Cd-18-0151 |
0.39 |
|
2018 |
Blakeley JO, Wolkenstein P, Widemann BC, Lee J, Le LQ, Jackson R, Stathis M, Verma SK. Creating a comprehensive research strategy for cutaneous neurofibromas. Neurology. 91: S1-S4. PMID 29987129 DOI: 10.1212/Wnl.0000000000005789 |
0.304 |
|
2018 |
Allaway RJ, Gosline SJC, La Rosa S, Knight P, Bakker A, Guinney J, Le LQ. Cutaneous neurofibromas in the genomics era: current understanding and open questions. British Journal of Cancer. PMID 29695767 DOI: 10.1038/S41416-018-0073-2 |
0.353 |
|
2018 |
Fisher MJ, Belzberg AJ, de Blank P, De Raedt T, Elefteriou F, Ferner RE, Giovannini M, Harris GJ, Kalamarides M, Karajannis MA, Kim A, Lázaro C, Le LQ, Li W, Listernick R, et al. 2016 Children's Tumor Foundation conference on neurofibromatosis type 1, neurofibromatosis type 2, and schwannomatosis. American Journal of Medical Genetics. Part A. 176: 1258-1269. PMID 29681099 DOI: 10.1002/Ajmg.A.38675 |
0.371 |
|
2018 |
Cooper JM, Patel AJ, Chen Z, Liao C, Chen K, Wang Y, Le LQ. Abstract 5797: BET inhibitor synthetic lethality in malignant peripheral nerve sheath tumors Cancer Research. 78: 5797-5797. DOI: 10.1158/1538-7445.Am2018-5797 |
0.354 |
|
2018 |
Chen Z, Le L. 762 Stem cell origin and spatio-temporal loss of heterozygosity give rise to different types of NF1-associated neurofibroma Journal of Investigative Dermatology. 138: S129. DOI: 10.1016/J.Jid.2018.03.772 |
0.326 |
|
2017 |
Liao CP, Booker RC, Morrison SJ, Le LQ. Identification of hair shaft progenitors that create a niche for hair pigmentation. Genes & Development. PMID 28465357 DOI: 10.1101/Gad.298703.117 |
0.301 |
|
2016 |
Liao CP, Pradhan S, Chen Z, Patel AJ, Booker RC, Le LQ. The role of nerve microenvironment for neurofibroma development. Oncotarget. PMID 27517146 DOI: 10.18632/Oncotarget.11133 |
0.364 |
|
2014 |
Chen Z, Liu C, Patel AJ, Liao CP, Wang Y, Le LQ. Cells of origin in the embryonic nerve roots for NF1-associated plexiform neurofibroma. Cancer Cell. 26: 695-706. PMID 25446898 DOI: 10.1016/J.Ccell.2014.09.009 |
0.4 |
|
2014 |
Patel AJ, Liao CP, Chen Z, Liu C, Wang Y, Le LQ. BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction. Cell Reports. 6: 81-92. PMID 24373973 DOI: 10.1016/J.Celrep.2013.12.001 |
0.363 |
|
2014 |
Chau V, Lim SK, Mo W, Liu C, Patel AJ, McKay RM, Wei S, Posner BA, De Brabander JK, Williams NS, Parada LF, Le LQ. Preclinical therapeutic efficacy of a novel pharmacologic inducer of apoptosis in malignant peripheral nerve sheath tumors. Cancer Research. 74: 586-97. PMID 24285727 DOI: 10.1158/0008-5472.Can-13-1934 |
0.371 |
|
2014 |
Patel AJ, Liao C, Chen Z, Liu C, Wang Y, Le LQ. Abstract 3117: BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction Cancer Research. 74: 3117-3117. DOI: 10.1158/1538-7445.Am2014-3117 |
0.359 |
|
2013 |
Mo W, Chen J, Patel A, Zhang L, Chau V, Li Y, Cho W, Lim K, Xu J, Lazar AJ, Creighton CJ, Bolshakov S, McKay RM, Lev D, Le LQ, et al. CXCR4/CXCL12 mediate autocrine cell- cycle progression in NF1-associated malignant peripheral nerve sheath tumors. Cell. 152: 1077-90. PMID 23434321 DOI: 10.1016/J.Cell.2013.01.053 |
0.415 |
|
2011 |
Le LQ, Liu C, Shipman T, Chen Z, Suter U, Parada LF. Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development. Cancer Research. 71: 4686-95. PMID 21551250 DOI: 10.1158/0008-5472.Can-10-4577 |
0.401 |
|
2009 |
Le LQ, Shipman T, Burns DK, Parada LF. Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas. Cell Stem Cell. 4: 453-63. PMID 19427294 DOI: 10.1016/J.Stem.2009.03.017 |
0.404 |
|
2007 |
Le LQ, Parada LF. Tumor microenvironment and neurofibromatosis type I: connecting the GAPs. Oncogene. 26: 4609-16. PMID 17297459 DOI: 10.1038/Sj.Onc.1210261 |
0.401 |
|
2005 |
Witte ON, Kabarowski JH, Xu Y, Le LQ, Zhu K. Retraction. Science (New York, N.Y.). 307: 206. PMID 15653487 DOI: 10.1126/science.307.5707.206b |
0.31 |
|
2002 |
Le LQ, Kabarowski JH, Wong S, Nguyen K, Gambhir SS, Witte ON. Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene. Cancer Cell. 1: 381-91. PMID 12086852 DOI: 10.1016/S1535-6108(02)00058-2 |
0.607 |
|
2001 |
Kabarowski JH, Zhu K, Le LQ, Witte ON, Xu Y. Lysophosphatidylcholine as a ligand for the immunoregulatory receptor G2A. Science (New York, N.Y.). 293: 702-5. PMID 11474113 DOI: 10.1126/Science.1061781 |
0.492 |
|
2001 |
Le LQ, Kabarowski JH, Weng Z, Satterthwaite AB, Harvill ET, Jensen ER, Miller JF, Witte ON. Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome. Immunity. 14: 561-71. PMID 11371358 DOI: 10.1016/S1074-7613(01)00145-5 |
0.508 |
|
2000 |
Kabarowski JH, Feramisco JD, Le LQ, Gu JL, Luoh SW, Simon MI, Witte ON. Direct genetic demonstration of G alpha 13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement. Proceedings of the National Academy of Sciences of the United States of America. 97: 12109-14. PMID 11050239 DOI: 10.1073/Pnas.97.22.12109 |
0.49 |
|
1998 |
Weng Z, Fluckiger AC, Nisitani S, Wahl MI, Le LQ, Hunter CA, Fernal AA, Le Beau MM, Witte ON. A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M. Proceedings of the National Academy of Sciences of the United States of America. 95: 12334-9. PMID 9770487 DOI: 10.1073/Pnas.95.21.12334 |
0.501 |
|
1998 |
Lieberman JR, Le LQ, Wu L, Finerman GA, Berk A, Witte ON, Stevenson S. Regional gene therapy with a BMP-2-producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents. Journal of Orthopaedic Research : Official Publication of the Orthopaedic Research Society. 16: 330-9. PMID 9671928 DOI: 10.1002/Jor.1100160309 |
0.45 |
|
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