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Kenneth M. Blumenthal - Publications

Affiliations: 
Biochemistry State University of New York, Buffalo, Buffalo, NY, United States 
Area:
Biochemistry, General Biophysics
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37 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Xiao Y, Blumenthal K, Cummins TR. Gating-pore currents demonstrate selective and specific modulation of individual sodium channel voltage-sensors by biological toxins. Molecular Pharmacology. 86: 159-67. PMID 24898004 DOI: 10.1124/Mol.114.092338  0.403
2010 Xiao Y, Blumenthal K, Jackson JO, Liang S, Cummins TR. The tarantula toxins ProTx-II and huwentoxin-IV differentially interact with human Nav1.7 voltage sensors to inhibit channel activation and inactivation. Molecular Pharmacology. 78: 1124-34. PMID 20855463 DOI: 10.1124/Mol.110.066332  0.414
2010 Edgerton GB, Blumenthal KM, Hanck DA. Inhibition of the activation pathway of the T-type calcium channel Ca(V)3.1 by ProTxII. Toxicon : Official Journal of the International Society On Toxinology. 56: 624-36. PMID 20600227 DOI: 10.1016/J.Toxicon.2010.06.009  0.444
2009 Edgerton GB, Hall E, Blumenthal KM, Hanck D. Charge-dependent And Isoform-specific Interactions Between ProTxii And T-type Calcium Channels Biophysical Journal. 96: 182a. DOI: 10.1016/J.Bpj.2008.12.852  0.473
2009 Edgerton GB, Campos FV, Blumenthal KM, Bezanilla F, Hanck DA. ProTxII Interacts Specifically with the Domain II Voltage Sensor of NaV1.4 Modifying Gating Without Immobilization Biophysical Journal. 96: 248a. DOI: 10.1016/J.Bpj.2008.12.1220  0.444
2008 Edgerton GB, Blumenthal KM, Hanck DA. Evidence for multiple effects of ProTxII on activation gating in Na(V)1.5. Toxicon : Official Journal of the International Society On Toxinology. 52: 489-500. PMID 18657562 DOI: 10.1016/J.Toxicon.2008.06.023  0.487
2007 Smith JJ, Cummins TR, Alphy S, Blumenthal KM. Molecular interactions of the gating modifier toxin ProTx-II with NaV 1.5: implied existence of a novel toxin binding site coupled to activation. The Journal of Biological Chemistry. 282: 12687-97. PMID 17339321 DOI: 10.1074/Jbc.M610462200  0.758
2007 Smith JJ, Blumenthal KM. Site-3 sea anemone toxins: molecular probes of gating mechanisms in voltage-dependent sodium channels. Toxicon : Official Journal of the International Society On Toxinology. 49: 159-70. PMID 17095031 DOI: 10.1016/J.Toxicon.2006.09.020  0.696
2007 Priest BT, Blumenthal KM, Smith JJ, Warren VA, Smith MM. ProTx-I and ProTx-II: gating modifiers of voltage-gated sodium channels. Toxicon : Official Journal of the International Society On Toxinology. 49: 194-201. PMID 17087985 DOI: 10.1016/J.Toxicon.2006.09.014  0.693
2006 Kashlan OB, Maarouf AB, Kussius C, Denshaw RM, Blumenthal KM, Kleyman TR. Distinct structural elements in the first membrane-spanning segment of the epithelial sodium channel. The Journal of Biological Chemistry. 281: 30455-62. PMID 16912051 DOI: 10.1074/jbc.M604615200  0.501
2005 Lis M, Blumenthal K. A modified, dual reporter TOXCAT system for monitoring homodimerization of transmembrane segments of proteins. Biochemical and Biophysical Research Communications. 339: 321-4. PMID 16297866 DOI: 10.1016/J.Bbrc.2005.11.022  0.33
2005 Smith JJ, Alphy S, Seibert AL, Blumenthal KM. Differential phospholipid binding by site 3 and site 4 toxins. Implications for structural variability between voltage-sensitive sodium channel domains. The Journal of Biological Chemistry. 280: 11127-33. PMID 15632158 DOI: 10.1074/Jbc.M412552200  0.717
2004 Seibert AL, Liu J, Hanck DA, Blumenthal KM. Role of Asn-16 and Ser-19 in anthopleurin B binding. Implications for the electrostatic nature of Na(V) site 3. Biochemistry. 43: 7082-9. PMID 15170345 DOI: 10.1021/Bi0496135  0.743
2003 Seibert AL, Liu J, Hanck DA, Blumenthal KM. Arg-14 loop of site 3 anemone toxins: effects of glycine replacement on toxin affinity. Biochemistry. 42: 14515-21. PMID 14661964 DOI: 10.1021/Bi035291D  0.745
2003 Blumenthal KM, Seibert AL. Voltage-gated sodium channel toxins: poisons, probes, and future promise. Cell Biochemistry and Biophysics. 38: 215-38. PMID 12777715 DOI: 10.1385/CBB:38:2:215  0.733
2000 Howell ML, Alsabbagh E, Ma JF, Ochsner UA, Klotz MG, Beveridge TJ, Blumenthal KM, Niederhoffer EC, Morris RE, Needham D, Dean GE, Wani MA, Hassett DJ. AnkB, a periplasmic ankyrin-like protein in Pseudomonas aeruginosa, is required for optimal catalase B (KatB) activity and resistance to hydrogen peroxide Journal of Bacteriology. 182: 4545-4556. PMID 10913088 DOI: 10.1128/Jb.182.16.4545-4556.2000  0.31
1998 Kelso GJ, Blumenthal KM. Identification and characterization of novel sodium channel toxins from the sea anemone Anthopleura xanthogrammica. Toxicon : Official Journal of the International Society On Toxinology. 36: 41-51. PMID 9604281 DOI: 10.1016/S0041-0101(97)00064-0  0.545
1998 Benzinger GR, Kyle JW, Blumenthal KM, Hanck DA. A specific interaction between the cardiac sodium channel and site-3 toxin anthopleurin B Journal of Biological Chemistry. 273: 80-84. PMID 9417050 DOI: 10.1074/jbc.273.1.80  0.586
1997 Wen PH, Blumenthal KM. Structure and function of Cerebratulus lacteus neurotoxin B-IV: tryptophan-30 is critical for function while lysines-18, -19, -29, and -33 are not required. Biochemistry. 36: 13435-40. PMID 9341237 DOI: 10.1021/Bi970957N  0.498
1997 Wen PH, Blumenthal KM. Role of electrostatic interactions in defining the potency of neurotoxin B-IV from Cerebratulus lacteus. The Journal of Biological Chemistry. 271: 29752-8. PMID 8939911 DOI: 10.1074/Jbc.271.47.29752  0.435
1996 Kelso GJ, Drum CL, Hanck DA, Blumenthal KM. Role for Pro-13 in directing high-affinity binding of anthopleurin B to the voltage-sensitive sodium channel Biochemistry. 35: 14157-14164. PMID 8916901 DOI: 10.1021/Bi961584D  0.599
1996 Dias-Kadambi BL, Combs KA, Drum CL, Hanck DA, Blumenthal KM. The role of exposed tryptophan residues in the activity of the cardiotonic polypeptide anthopleurin B Journal of Biological Chemistry. 271: 23828-23835. PMID 8798612 DOI: 10.1074/Jbc.271.39.23828  0.664
1996 Khera PK, Blumenthal KM. Importance of highly conserved anionic residues and electrostatic interactions in the activity and structure of the cardiotonic polypeptide anthopleurin B. Biochemistry. 35: 3503-7. PMID 8639500 DOI: 10.1021/Bi9528457  0.531
1996 Dias-Kadambi BL, Drum CL, Hanck DA, Blumenthal KM. Leucine 18, a hydrophobic residue essential for high affinity binding of anthopleurin B to the voltage-sensitive sodium channel Journal of Biological Chemistry. 271: 9422-9428. PMID 8621610 DOI: 10.1074/Jbc.271.16.9422  0.617
1995 Khera PK, Benzinger GR, Lipkind G, Drum CL, Hanck DA, Blumenthal KM. Multiple cationic residues of anthopleurin B that determine high affinity and channel isoform discrimination Biochemistry. 34: 8533-8541. PMID 7612595 DOI: 10.1021/bi00027a003  0.553
1991 Liu J, Blumenthal KM. Identification of oleic acid binding sites in cytolysin A-III from the heteronemertine Cerebratulus lacteus. Toxicon : Official Journal of the International Society On Toxinology. 29: 13-20. PMID 1902999 DOI: 10.1016/0041-0101(91)90035-P  0.392
1989 Cuppoletti J, Blumenthal KM, Malinowska DH. Melittin inhibition of the gastric (H+ + K+) ATPase and photoaffinity labeling with [125I]azidosalicylyl melittin. Archives of Biochemistry and Biophysics. 275: 263-70. PMID 2554808 DOI: 10.1016/0003-9861(89)90372-X  0.34
1988 Liu JW, Blumenthal KM. Membrane damage by Cerebratulus lacteus cytolysin A-III. Effects of monovalent and divalent cations on A-III hemolytic activity. Biochimica Et Biophysica Acta. 937: 153-60. PMID 3334843 DOI: 10.1016/0005-2736(88)90237-4  0.411
1986 Blumenthal KM. Renaturation of neurotoxin B-IV from the heteronemertine Cerebratulus lacteus. Toxicon : Official Journal of the International Society On Toxinology. 24: 63-9. PMID 3952765 DOI: 10.1016/0041-0101(86)90166-2  0.348
1986 Lieberman DL, Blumenthal KM. Structure and action of heteronemertine polypeptide toxins. Specific cross-linking of Cerebratulus lacteus toxin B-IV to lobster axon membrane vesicles. Biochimica Et Biophysica Acta. 855: 41-8. PMID 3942745 DOI: 10.1016/0005-2736(86)90186-0  0.39
1985 Dumont JA, Blumenthal KM. Structure and action of heteronemertine polypeptide toxins: importance of amphipathic helix for activity of Cerebratulus lacteus toxin A-III. Archives of Biochemistry and Biophysics. 236: 167-75. PMID 3881082 DOI: 10.1016/0003-9861(85)90616-2  0.467
1985 Blumenthal KM. Binding of Cerebratulus cytolysin A-III to human erythrocyte membranes. Biochimica Et Biophysica Acta. 812: 127-32. PMID 3843929 DOI: 10.1016/0005-2736(85)90529-2  0.457
1983 Toth GP, Blumenthal KM. Structure and action of heteronemertine polypeptide toxins Binding of cerebratulus lacteus toxin B-IV to axon membrane vesicles Biochimica Et Biophysica Acta (Bba) - Biomembranes. 732: 160-169. DOI: 10.1016/0005-2736(83)90199-2  0.484
1982 Blumenthal KM. Structure and action of heteronemertine polypeptide toxins. Membrane penetration by Cerebratulus lacteus toxin A-III. Biochemistry. 21: 4229-33. PMID 7126540 DOI: 10.1021/Bi00261A007  0.385
1981 Panini A, Blumenthal K. Effects of N-ethylmaleimide treatment on the action potential Na+-ionophore of cultured neuroblastoma cells. Journal of Neurochemistry. 35: 707-12. PMID 6256495 DOI: 10.1111/J.1471-4159.1980.Tb03709.X  0.45
1980 Blumenthal KM, Kem WR. Structure and action of heteronemertine polypeptide toxins: inactivation of Cerebratulus lacteus toxin B-IV by tyrosine nitration. Archives of Biochemistry and Biophysics. 203: 816-21. PMID 7458356 DOI: 10.1016/0003-9861(80)90243-X  0.478
1979 Richardson C, Behnke WD, Freisheim JH, Blumenthal KM. The complete amino acid sequence of the alpha-subunit of pea lectin, Pisum sativum. Biochimica Et Biophysica Acta. 537: 310-9. PMID 728447 DOI: 10.1016/0005-2795(78)90514-7  0.363
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