Vivek Mittal, Ph.D. - Publications

Affiliations: 
2005 Washington University, Saint Louis, St. Louis, MO 
Area:
Biochemistry, Molecular Biology

96 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Crowley MJP, Bhinder B, Markowitz GJ, Martin M, Verma A, Sandoval TA, Chae CS, Yomtoubian S, Hu Y, Chopra S, Tavarez DA, Giovanelli P, Gao D, McGraw TE, Altorki NK, ... ... Mittal V, et al. Tumor-intrinsic IRE1α signaling controls protective immunity in lung cancer. Nature Communications. 14: 120. PMID 36624093 DOI: 10.1038/s41467-022-35584-9  0.335
2022 Sui L, Wang S, Ganguly D, El Rayes TP, Askeland C, Børretzen A, Sim D, Halvorsen OJ, Knutsvik G, Arnes J, Aziz S, Haukaas S, Foulkes WD, Bielenberg DR, Ziemys A, ... Mittal V, et al. PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression. Nature Communications. 13: 7959. PMID 36575174 DOI: 10.1038/s41467-022-35649-9  0.326
2022 Altorki NK, Borczuk AC, Harrison S, Groner LK, Bhinder B, Mittal V, Elemento O, McGraw TE. Global evolution of the tumor microenvironment associated with progression from preinvasive invasive to invasive human lung adenocarcinoma. Cell Reports. 39: 110639. PMID 35385730 DOI: 10.1016/j.celrep.2022.110639  0.319
2020 Ramchandani D, Mittal V. Thrombospondin in Tumor Microenvironment. Advances in Experimental Medicine and Biology. 1272: 133-147. PMID 32845506 DOI: 10.1007/978-3-030-48457-6_8  0.42
2020 Au CC, Furness JB, Britt K, Oshchepkova S, Ladumor H, Soo KY, Callaghan B, Gerard C, Inghirami G, Mittal V, Wang Y, Huang XY, Spector JA, Andreopoulou E, Zumbo P, et al. Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531. Elife. 9. PMID 32667883 DOI: 10.7554/Elife.56913  0.404
2020 Yomtoubian S, Lee SB, Verma A, Izzo F, Markowitz G, Choi H, Cerchietti L, Vahdat L, Brown KA, Andreopoulou E, Elemento O, Chang J, Inghirami G, Gao D, Ryu S, ... Mittal V, et al. Inhibition of EZH2 Catalytic Activity Selectively Targets a Metastatic Subpopulation in Triple-Negative Breast Cancer. Cell Reports. 30: 755-770.e6. PMID 31968251 DOI: 10.1016/J.Celrep.2019.12.056  0.39
2020 Au CC, Furness JB, Britt K, Oshchepkova S, Ladumor H, Soo KY, Callaghan B, Gerard C, Inghirami G, Mittal V, Wang Y, Huang XY, Spector JA, Andreopoulou E, Zumbo P, et al. Author response: Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531 Elife. DOI: 10.7554/Elife.56913.Sa2  0.399
2019 Altorki NK, Markowitz GJ, Gao D, Port JL, Saxena A, Stiles B, McGraw T, Mittal V. The lung microenvironment: an important regulator of tumour growth and metastasis. Nature Reviews. Cancer. 19: 9-31. PMID 30532012 DOI: 10.1038/S41568-018-0081-9  0.351
2019 Liu Y, Bager C, Willumsen N, Kornhauser N, Cobham M, Andreopoulou E, Cigler T, Moore A, LaPolla D, Fitzpatrick V, Ward M, Warren J, Mittal V, Vahdat L. Abstract PD9-07: A phase II study of copper-depletion using tetrathiomolybdate (TM) in patients (pts) with high risk breast cancer (BC): Role of collagen processing and tumor microenvironment Cancer Research. 79. DOI: 10.1158/1538-7445.Sabcs18-Pd9-07  0.381
2018 Gao D, Mittal V, Ban Y, Lourenco AR, Yomtoubian S, Lee S. Metastatic tumor cells - genotypes and phenotypes. Frontiers in Biology. 13: 277-286. PMID 30774650 DOI: 10.1007/S11515-018-1513-3  0.443
2018 Markowitz GJ, Havel LS, Crowley MJ, Ban Y, Lee SB, Thalappillil JS, Narula N, Bhinder B, Elemento O, Wong ST, Gao D, Altorki NK, Mittal V. Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival. Jci Insight. 3. PMID 29997286 DOI: 10.1172/Jci.Insight.96836  0.342
2018 Mittal V. Epithelial Mesenchymal Transition in Tumor Metastasis. Annual Review of Pathology. 13: 395-412. PMID 29414248 DOI: 10.1146/Annurev-Pathol-020117-043854  0.419
2018 Sahota S, Willis A, Kornhauser N, Ward M, Cobham M, Cigler T, Moore A, Andreopoulou E, Fitzpatrick V, Schneider S, Prima N, Wiener A, Ko D, Laurentiis AD, Warren J, ... ... Mittal V, et al. Abstract P1-10-02: A phase II study of copper-depletion using tetrathiomolybdate in patients with breast cancer at high risk for recurrence: Updated results Cancer Research. 78. DOI: 10.1158/1538-7445.Sabcs17-P1-10-02  0.408
2017 Cao Z, Ye T, Sun Y, Ji G, Shido K, Chen Y, Luo L, Na F, Li X, Huang Z, Ko JL, Mittal V, Qiao L, Chen C, Martinez FJ, et al. Targeting the vascular and perivascular niches as a regenerative therapy for lung and liver fibrosis. Science Translational Medicine. 9. PMID 28855398 DOI: 10.1126/Scitranslmed.Aai8710  0.331
2017 Chen M, Nowak DG, Narula N, Robinson B, Watrud K, Ambrico A, Herzka TM, Zeeman ME, Minderer M, Zheng W, Ebbesen SH, Plafker KS, Stahlhut C, Wang VM, Wills L, ... ... Mittal V, et al. The nuclear transport receptor Importin-11 is a tumor suppressor that maintains PTEN protein. The Journal of Cell Biology. PMID 28193700 DOI: 10.1083/Jcb.201604025  0.421
2017 Sahota S, Kornhauser N, Willis A, Ward MM, Cigler T, Moore A, Andreopoulou E, Fitzpatrick V, Schneider SE, Wiener A, Rubinchik A, Lee S, Lane ME, Mittal V, Vahdat LT. A phase II study of copper-depletion using tetrathiomolybdate (TM) in patients (pts) with breast cancer (BC) at high risk for recurrence: Updated results. Journal of Clinical Oncology. 35: 2557-2557. DOI: 10.1200/Jco.2017.35.15_Suppl.2557  0.395
2017 Yomtoubian S, Ryu S, Lee S, Markowitz G, Gao D, Mittal V. Abstract 5078: EZH2 methyltransferase regulates disseminating tumor cells in breast cancer metastasis Cancer Research. 77: 5078-5078. DOI: 10.1158/1538-7445.Am2017-5078  0.485
2017 Lopez J, Bednarczyk R, Altorki N, Mittal V, Gao D. Abstract 4944: Modeling tumor dormancy by using EMT lineage tracing under chemotherapy Cancer Research. 77: 4944-4944. DOI: 10.1158/1538-7445.Am2017-4944  0.369
2017 Crowley MJ, Yomtoubian S, Markowitz G, Altorki NK, Gao D, Cubillos-Ruiz J, Mittal V. Abstract 4498: Targeting IRE1a-XBP1 signaling in lung cancer Cancer Research. 77: 4498-4498. DOI: 10.1158/1538-7445.Am2017-4498  0.461
2017 Crowley MJ, Altorki N, Mittal V, Gao D. Abstract 3196: Genetic and pharmacologic approaches to overcome epithelial to mesenchymal mediated chemoresistance in breast cancer Cancer Research. 77: 3196-3196. DOI: 10.1158/1538-7445.Am2017-3196  0.333
2017 Markowitz GJ, Philip M, Schietinger A, Mittal V. Abstract 1670: Identification and characterization of novel mediators of tumor-induced T-cell dysfunction Immunology. 77: 1670-1670. DOI: 10.1158/1538-7445.Am2017-1670  0.363
2016 Stawowczyk M, Wellenstein MD, Lee SB, Yomtoubian S, Durrans A, Choi H, Narula N, Altorki NK, Gao D, Mittal V. Matrix Metalloproteinase 14 promotes lung cancer by cleavage of Heparin-Binding EGF-like Growth Factor. Neoplasia (New York, N.Y.). 19: 55-64. PMID 28013056 DOI: 10.1016/J.Neo.2016.11.005  0.38
2016 Sax MJ, Gasch C, Athota VR, Freeman R, Rasighaemi P, Westcott DE, Day CJ, Nikolic I, Elsworth B, Wei M, Rogers K, Swarbrick A, Mittal V, Pouliot N, Mellick AS. Cancer cell CCL5 mediates bone marrow independent angiogenesis in breast cancer. Oncotarget. PMID 27863423 DOI: 10.18632/Oncotarget.13387  0.472
2016 Chan N, Willis A, Kornhauser N, Ward MM, Lee SB, Nackos E, Seo BR, Chuang E, Cigler T, Moore A, Donovan D, Vallee Cobham M, Fitzpatrick V, Schneider S, Wiener A, ... ... Mittal V, et al. Influencing the tumor microenvironment: Phase 2 Study of Copper depletion with tetrathiomolybdate in high risk breast cancer and preclinical models of lung metastases. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27769988 DOI: 10.1158/1078-0432.Ccr-16-1326  0.446
2016 Wang D, Narula N, Azzopardi S, Smith RS, Nasar A, Altorki NK, Mittal V, Somwar R, Stiles BM, Du YN. Expression of the receptor for hyaluronic acid mediated motility (RHAMM) is associated with poor prognosis and metastasis in non-small cell lung carcinoma. Oncotarget. PMID 27220886 DOI: 10.18632/Oncotarget.9554  0.354
2016 Wang S, Blois A, El Rayes T, Liu JF, Hirsch MS, Gravdal K, Palakurthi S, Bielenberg DR, Akslen LA, Drapkin R, Mittal V, Watnick RS. Development of a prosaposin-derived therapeutic cyclic peptide that targets ovarian cancer via the tumor microenvironment. Science Translational Medicine. 8: 329ra34. PMID 26962158 DOI: 10.1126/Scitranslmed.Aad5653  0.433
2016 Zhao Z, Zhu X, Cui K, Mancuso J, Federley R, Fischer K, Teng G, Mittal V, Gao D, Zhao H, Wong ST. In vivo visualization and characterization of epithelial-mesenchymal transition in breast tumors. Cancer Research. PMID 26893478 DOI: 10.1158/0008-5472.Can-15-2662  0.439
2016 Mittal V, El Rayes T, Narula N, McGraw TE, Altorki NK, Barcellos-Hoff MH. The Microenvironment of Lung Cancer and Therapeutic Implications. Advances in Experimental Medicine and Biology. 890: 75-110. PMID 26703800 DOI: 10.1007/978-3-319-24932-2_5  0.441
2016 Mittal V. Epithelial Mesenchymal Transition in Aggressive Lung Cancers. Advances in Experimental Medicine and Biology. 890: 37-56. PMID 26703798 DOI: 10.1007/978-3-319-24932-2_3  0.445
2016 Havel LS, Gao D, Altorki N, Mittal V. Abstract B172: Oncogene-mediated immune microenvironments in lung cancer provide a rationale for combination therapies Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B172  0.357
2016 Wang S, Blois A, Rayes TE, Liu JF, Hirsch MS, Gravdal K, Bielenberg DR, Akslen LA, Drapkin R, Mittal V, Watnick RS. Abstract A18: Development of a novel peptide therapeutic that targets ovarian cancer via the tumor microenvironment Cancer Research. 76. DOI: 10.1158/1538-7445.Tummet15-A18  0.442
2016 Nackos E, Lee S, Willis A, Kornhauser N, Ward M, Cobham M, Cigler T, Moore A, Fitzpatrick V, Schneider S, Wiener A, Guillaume-Abraham J, Seo BR, Warren JD, Rubinchik A, ... ... Mittal V, et al. Abstract LB-349: Copper depletion as a strategy to affect the tumor microenvironment in breast cancer patients at high risk of relapse and in triple negative preclinical models of breast cancer: Updated results of a phase II study of tetrathiomolybdate (TM) in breast cancer (BC) patients (pts) at high risk for recurrence Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Lb-349  0.427
2016 Yomtoubian S, Ryu S, Lee S, Havel L, Gao D, Mittal V. Abstract 4447: EZH2 contributes to breast cancer metastasis Cancer Research. 76: 4447-4447. DOI: 10.1158/1538-7445.Am2016-4447  0.414
2016 Havel LS, Gao D, Daniel JS, Altorki NK, Mittal V. Targeting immunosuppressive mechanisms in KRAS mutant lung cancer Journal of Thoracic Oncology. 11: S23-S24. DOI: 10.1016/J.Jtho.2015.12.039  0.404
2015 El Rayes T, Catena R, Lee S, Stawowczyk M, Joshi N, Fischbach C, Powell CA, Dannenberg AJ, Altorki NK, Gao D, Mittal V. Lung inflammation promotes metastasis through neutrophil protease-mediated degradation of Tsp-1. Proceedings of the National Academy of Sciences of the United States of America. PMID 26668367 DOI: 10.1073/Pnas.1507294112  0.378
2015 Fischer KR, Durrans A, Lee S, Sheng J, Li F, Wong ST, Choi H, El Rayes T, Ryu S, Troeger J, Schwabe RF, Vahdat LT, Altorki NK, Mittal V, Gao D. Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance. Nature. PMID 26560033 DOI: 10.1038/Nature15748  0.391
2015 Durrans A, Gao D, Gupta R, Fischer KR, Choi H, El Rayes T, Ryu S, Nasar A, Spinelli CF, Andrews W, Elemento O, Nolan D, Stiles B, Rafii S, Narula N, ... ... Mittal V, et al. Identification of Reprogrammed Myeloid Cell Transcriptomes in NSCLC. Plos One. 10: e0129123. PMID 26046767 DOI: 10.1371/Journal.Pone.0129123  0.447
2015 Choi H, Sheng J, Gao D, Li F, Durrans A, Ryu S, Lee SB, Narula N, Rafii S, Elemento O, Altorki NK, Wong ST, Mittal V. Transcriptome analysis of individual stromal cell populations identifies stroma-tumor crosstalk in mouse lung cancer model. Cell Reports. 10: 1187-201. PMID 25704820 DOI: 10.1016/J.Celrep.2015.01.040  0.471
2015 Nackos EN, Kornhauser N, Ward MM, Cigler T, Moore A, Andreopoulou E, Chan N, Fitzpatrick V, Schneider SE, Wiener A, Warren JD, Rubinchik A, Willis A, Lee S, Lane ME, ... Mittal V, et al. Altering the tumor microenvironment: A phase II study of copper depletion using tetrathiomolybdate (TM) in patients (pts) with breast cancer (BC) at high risk for recurrence. Journal of Clinical Oncology. 33: 11008-11008. DOI: 10.1200/Jco.2015.33.15_Suppl.11008  0.428
2015 Fischer KR, Durrans A, Lee S, Sheng J, Choi H, Li F, Wong S, Altorki NK, Mittal V, Gao D. Abstract 4721: Epithelial to mesenchymal transition is not required for breast to lung metastasis but contributes to chemoresistance Cancer Research. 75: 4721-4721. DOI: 10.1158/1538-7445.Am2015-4721  0.463
2015 Choi H, Shen J, Durrans A, Rayes TE, Fischer K, Gao D, Wong S, Altorki N, Mittal V. Abstract 3214: Genome-wide analysis of stroma-tumor crosstalk pathways in lung cancer: therapeutic implications Cancer Research. 75: 3214-3214. DOI: 10.1158/1538-7445.Am2015-3214  0.395
2015 Rayes TE, Catena R, Rafii S, Altorki N, Mittal V. Inflammation and Lung Cancer: The Link to Angiogenesis Springer: New York. 137-159. DOI: 10.1007/978-1-4939-2724-1_5  0.376
2014 Dave B, Granados-Principal S, Zhu R, Benz S, Rabizadeh S, Soon-Shiong P, Yu KD, Shao Z, Li X, Gilcrease M, Lai Z, Chen Y, Huang TH, Shen H, Liu X, ... ... Mittal V, et al. Targeting RPL39 and MLF2 reduces tumor initiation and metastasis in breast cancer by inhibiting nitric oxide synthase signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 8838-43. PMID 24876273 DOI: 10.1073/Pnas.1320769111  0.454
2014 Nair R, Teo WS, Mittal V, Swarbrick A. ID proteins regulate diverse aspects of cancer progression and provide novel therapeutic opportunities. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 1407-15. PMID 24827908 DOI: 10.1038/Mt.2014.83  0.416
2014 Chan N, Kornhauser N, Ward M, Willis A, Cigler T, Chuang E, Moore A, Donovan D, Schneider SE, Lam C, Warren DJ, Rubinchik A, Rua SH, Lee S, Lane M, ... Mittal V, et al. Abstract CT309: Influencing the tumor microenvironment: A phase II study of copper-depletion using tetrathiomolybdate (TM) in patients (pts) with breast cancer (BC) at high risk for recurrence Cancer Research. 74. DOI: 10.1158/1538-7445.Am2014-Ct309  0.397
2014 Rayes TE, Catena R, Lee S, Gao D, Stawowczyk M, Altorki N, Mittal V. Abstract 2073: Neutrophil serine proteases, cathepsin-G and elastase, promote metastasis through cleavage of thrombospondin-1 Cancer Research. 74: 2073-2073. DOI: 10.1158/1538-7445.Am2014-2073  0.387
2014 Choi H, Gao DC, Lee SB, Durrans A, Ryu S, Elemento O, Wong S, Altorki NK, Mittal V. Abstract 1159: A novel HGF-MET paracrine signaling pathway promotes growth and resistance to chemotherapy in lung cancer Cancer Research. 74: 1159-1159. DOI: 10.1158/1538-7445.Am2014-1159  0.429
2013 Shen H, Mittal V, Ferrari M, Chang J. Delivery of gene silencing agents for breast cancer therapy. Breast Cancer Research : Bcr. 15: 205. PMID 23659575 DOI: 10.1186/Bcr3413  0.367
2013 Catena R, Bhattacharya N, El Rayes T, Wang S, Choi H, Gao D, Ryu S, Joshi N, Bielenberg D, Lee SB, Haukaas SA, Gravdal K, Halvorsen OJ, Akslen LA, Watnick RS, ... Mittal V, et al. Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1. Cancer Discovery. 3: 578-89. PMID 23633432 DOI: 10.1158/2159-8290.Cd-12-0476  0.402
2013 Jain S, Cohen J, Ward MM, Kornhauser N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham MV, Schneider S, Hurtado Rúa SM, Benkert S, Mathijsen Greenwood C, Zelkowitz R, ... ... Mittal V, et al. Tetrathiomolybdate-associated copper depletion decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse. Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 24: 1491-8. PMID 23406736 DOI: 10.1093/Annonc/Mds654  0.356
2013 Ryu S, McDonnell K, Choi H, Gao D, Hahn M, Joshi N, Park SM, Catena R, Do Y, Brazin J, Vahdat LT, Silver RB, Mittal V. Suppression of miRNA-708 by polycomb group promotes metastases by calcium-induced cell migration. Cancer Cell. 23: 63-76. PMID 23328481 DOI: 10.1016/J.Ccr.2012.11.019  0.322
2013 Plummer PN, Freeman R, Taft RJ, Vider J, Sax M, Umer BA, Gao D, Johns C, Mattick JS, Wilton SD, Ferro V, McMillan NA, Swarbrick A, Mittal V, Mellick AS. MicroRNAs regulate tumor angiogenesis modulated by endothelial progenitor cells. Cancer Research. 73: 341-52. PMID 22836757 DOI: 10.1158/0008-5472.Can-12-0271  0.349
2013 Watnick RS, Mittal V, Catena R, Wang S, Reyes TE, Akslen L. Abstract IA17: Development of a therapeutic peptide for the treatment of metastatic cancer Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-Ia17  0.478
2013 Wang S, Catena R, Mittal V, Watnick RS. Abstract B4: Development of a short peptide with antitumor activity Cancer Research. 73. DOI: 10.1158/1538-7445.Tim2013-B4  0.438
2013 Durrans A, Gao D, Gupta R, Ryu S, Narula N, Fischer KR, Choi H, Stiles BM, Nasar A, Davuluri RV, Altorki NK, Mittal V. Abstract 4972: Analysis of the reprogrammed bone marrow-derived stroma in lung cancer unravels potential targets for prognosis and therapy. Cancer Research. 73: 4972-4972. DOI: 10.1158/1538-7445.Am2013-4972  0.342
2013 Catena R, Bhattacharya N, Rayes TE, Choi H, Wang S, Gao D, Joshi N, Ryu S, Bielenberg D, Lee S, Haukaas S, Gravdal K, Halvorsen O, Akslen L, Watnick R, ... Mittal V, et al. Abstract 4584: Bone marrow-derived Gr1+ cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1. Cancer Research. 73: 4584-4584. DOI: 10.1158/1538-7445.Am2013-4584  0.459
2013 Gao D, Fisher K, Choi H, Dannenberg AJ, Vahdat L, Altorki N, Mittal V. Abstract 301: Microenvironmental regulation of epithelial-mesenchymal transitions in breast cancer metastasis. Cancer Research. 73: 301-301. DOI: 10.1158/1538-7445.Am2013-301  0.476
2013 Dave B, Granados S, Mai J, Choi DS, Gao DC, Mitra S, Shen H, Muthuswamy S, Mittal V, Ferrari M, Chang J. Abstract 2712: Identification of tumor initiating genes RPL39 and MLF2 that mediate lung metastasis through nitric oxide signaling and mesenchymal to epithelial transition. Cancer Research. 73: 2712-2712. DOI: 10.1158/1538-7445.Am2013-2712  0.46
2013 Mellick AS, Plummer PN, Mittal V. Abstract 2309: Identification and targeting of small noncoding RNAs implicated in tumor angiogenesis. Cancer Research. 73: 2309-2309. DOI: 10.1158/1538-7445.Am2013-2309  0.455
2013 Choi H, Durrans A, Gao D, Ryu S, Altorki N, Mittal V. Abstract 1420: Mechanisms of stroma-derived CCL7 in promoting lung cancer. Cancer Research. 73: 1420-1420. DOI: 10.1158/1538-7445.Am2013-1420  0.452
2013 Chang JC, Dave B, Granados-Principal S, Mai J, Gross S, Shen H, Mittal V, Ferrari M. Abstract CN06-02: Breast cancer stem cells. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-Cn06-02  0.463
2012 Gao D, Vahdat LT, Wong S, Chang JC, Mittal V. Microenvironmental regulation of epithelial-mesenchymal transitionsin cancer Cancer Research. 72: 4883-4889. PMID 23002209 DOI: 10.1158/0008-5472.Can-12-1223  0.479
2012 Gao D, Mittal V. Tumor microenvironment regulates epithelial-mesenchymal transitions in metastasis. Expert Review of Anticancer Therapy. 12: 857-9. PMID 22845398 DOI: 10.1586/Era.12.69  0.382
2012 Gao D, Joshi N, Choi H, Ryu S, Hahn M, Catena R, Sadik H, Argani P, Wagner P, Vahdat LT, Port JL, Stiles B, Sukumar S, Altorki NK, Rafii S, ... Mittal V, et al. Myeloid progenitor cells in the premetastatic lung promote metastases by inducing mesenchymal to epithelial transition. Cancer Research. 72: 1384-94. PMID 22282653 DOI: 10.1158/0008-5472.Can-11-2905  0.447
2012 Dave B, Mittal V, Tan NM, Chang JC. Epithelial-mesenchymal transition, cancer stem cells and treatment resistance. Breast Cancer Research : Bcr. 14: 202. PMID 22264257 DOI: 10.1186/Bcr2938  0.411
2012 Jain S, Ward MM, O'Loughlin J, Boeck M, Wiener N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham MV, Schneider S, Christos P, Baergen RN, Swistel A, ... ... Mittal V, et al. Incremental increase in VEGFR1⁺ hematopoietic progenitor cells and VEGFR2⁺ endothelial progenitor cells predicts relapse and lack of tumor response in breast cancer patients. Breast Cancer Research and Treatment. 132: 235-42. PMID 22160642 DOI: 10.1007/S10549-011-1906-3  0.343
2012 Jain S, Rua SH, Cohen J, Ward MM, Boeck M, Wiener N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham M, Schneider S, Baergen R, Lane ME, ... Mittal V, et al. Abstract 2699: Phase II study evaluating the effect of tetrathiomolybdate on circulating endothelial progenitor cells in patients with high risk for breast cancer recurrence Cancer Research. 72: 2699-2699. DOI: 10.1158/1538-7445.Am2012-2699  0.394
2012 Jain S, Kornhauser N, Lam C, Ward M, Chuang E, Cigler T, Moore A, Donovan D, Cobham M, Schneider S, Hurtado RS, Lane M, Mittal V, Vahdat L. Abstract P6-11-04: Targeting the tumor microenvironment: tetrathiomolybdate decreases circulating endothelial progenitor cells in women with breast cancer at high risk of relapse. Cancer Research. 72. DOI: 10.1158/0008-5472.Sabcs12-P6-11-04  0.377
2012 Coppolino A, Gao DC, Wagner PL, Sordella R, Mittal V, Altorki NK, Stiles BM. Standard markers for detection of circulating tumor cells are variably expressed in pulmonary adenocarcinomas and are downregulated in cells undergoing mesenchymal transition Journal of the American College of Surgeons. 215: S40. DOI: 10.1016/J.Jamcollsurg.2012.06.122  0.342
2011 Jain S, Cohen JA, Ward MM, O'Loughlin J, Boeck M, Wiener N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham ME, Schneider SE, Christos PJ, Lane ME, ... ... Mittal V, et al. The effect of tetrathiomolybdate on endothelial progenitor cells in patients at high risk for breast cancer recurrence. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 1054. PMID 28020656 DOI: 10.1200/Jco.2011.29.15_Suppl.1054  0.409
2011 Jain S, Ward MM, O'Loughlin J, Boeck MA, Wiener N, Chuang E, Cigler T, Moore A, Donovan D, Lam C, Cobham MV, Schneider SE, Christos P, Baergen RN, Lane ME, ... Mittal V, et al. Abstract 4720: Incremental increase in VEGFR1+ and VEGFR2+ hemangiogenic progenitor cells predict relapse and tumor response in breast cancer (BC) patients Cancer Research. 71: 4720-4720. DOI: 10.1158/1538-7445.Am2011-4720  0.339
2010 Mellick AS, Plummer PN, Nolan DJ, Gao D, Bambino K, Hahn M, Catena R, Turner V, McDonnell K, Benezra R, Brink R, Swarbrick A, Mittal V. Using the transcription factor inhibitor of DNA binding 1 to selectively target endothelial progenitor cells offers novel strategies to inhibit tumor angiogenesis and growth. Cancer Research. 70: 7273-82. PMID 20807818 DOI: 10.1158/0008-5472.Can-10-1142  0.427
2010 Yao Z, Fenoglio S, Gao DC, Camiolo M, Stiles B, Lindsted T, Schlederer M, Johns C, Altorki N, Mittal V, Kenner L, Sordella R. TGF-beta IL-6 axis mediates selective and adaptive mechanisms of resistance to molecular targeted therapy in lung cancer. Proceedings of the National Academy of Sciences of the United States of America. 107: 15535-40. PMID 20713723 DOI: 10.1073/Pnas.1009472107  0.378
2010 Penack O, Henke E, Suh D, King CG, Smith OM, Na IK, Holland AM, Ghosh A, Lu SX, Jenq RR, Liu C, Murphy GF, Lu TT, May C, Scheinberg DA, ... ... Mittal V, et al. Inhibition of neovascularization to simultaneously ameliorate graft-vs-host disease and decrease tumor growth. Journal of the National Cancer Institute. 102: 894-908. PMID 20463307 DOI: 10.1093/Jnci/Djq172  0.388
2010 Gao D, Joshi N, Choi H, Ryu S, Hann M, Mittal V. Abstract 5765: Tumor-elicited myeloid progenitors promote metastasis through induction of mesenchymal to epithelial transition Cancer Research. 70: 5765-5765. DOI: 10.1158/1538-7445.Am10-5765  0.484
2010 Ryu S, Mittal V. Abstract 483: Genome-wide analysis identify molecular regulators of metastasis Cancer Research. 70: 483-483. DOI: 10.1158/1538-7445.Am10-483  0.403
2009 Gao D, Mittal V. The role of bone-marrow-derived cells in tumor growth, metastasis initiation and progression. Trends in Molecular Medicine. 15: 333-43. PMID 19665928 DOI: 10.1016/J.Molmed.2009.06.006  0.435
2009 Gao D, Nolan D, McDonnell K, Vahdat L, Benezra R, Altorki N, Mittal V. Bone marrow-derived endothelial progenitor cells contribute to the angiogenic switch in tumor growth and metastatic progression. Biochimica Et Biophysica Acta. 1796: 33-40. PMID 19460418 DOI: 10.1016/J.Bbcan.2009.05.001  0.426
2009 Hooper AT, Butler JM, Nolan DJ, Kranz A, Iida K, Kobayashi M, Kopp HG, Shido K, Petit I, Yanger K, James D, Witte L, Zhu Z, Wu Y, Pytowski B, ... ... Mittal V, et al. Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. Cell Stem Cell. 4: 263-74. PMID 19265665 DOI: 10.1016/J.Stem.2009.01.006  0.309
2009 Penack O, Henke E, Suh D, King C, Smith M, Na I, Holland A, Ghosh A, Lu S, Jenq R, Liu C, May C, Murphy G, Lu T, Gao D, ... Mittal V, et al. Depletion of Vascular Endothelial Progenitor Cells Simultaneously Ameliorates GVHD and Inhibits Tumor Growth Biology of Blood and Marrow Transplantation. 15: 1. DOI: 10.1016/J.Bbmt.2008.12.007  0.363
2008 Kerbel RS, Benezra R, Lyden DC, Hattori K, Heissig B, Nolan DJ, Mittal V, Shaked Y, Dias S, Bertolini F, Rafii S. Endothelial progenitor cells are cellular hubs essential for neoangiogenesis of certain aggressive adenocarcinomas and metastatic transition but not adenomas. Proceedings of the National Academy of Sciences of the United States of America. 105: E54; author reply E5. PMID 18715995 DOI: 10.1073/Pnas.0804876105  0.356
2008 Gao D, Nolan DJ, Mellick AS, Bambino K, McDonnell K, Mittal V. Endothelial progenitor cells control the angiogenic switch in mouse lung metastasis. Science (New York, N.Y.). 319: 195-8. PMID 18187653 DOI: 10.1126/Science.1150224  0.459
2008 Penack O, Henke E, Suh D, King C, Smith MO, Na I, Holland A, Ghosh A, Lu SX, Jenq R, Liu C, Murphy GF, Lu T, May C, Scheinberg DA, ... ... Mittal V, et al. Depletion of Vascular Endothelial Progenitor Cells Inhibits Inflammation Blood. 112: 694-694. DOI: 10.1182/Blood.V112.11.694.694  0.364
2007 Ciarrocchi A, Jankovic V, Shaked Y, Nolan DJ, Mittal V, Kerbel RS, Nimer SD, Benezra R. Id1 restrains p21 expression to control endothelial progenitor cell formation. Plos One. 2: e1338. PMID 18092003 DOI: 10.1371/Journal.Pone.0001338  0.401
2007 Gupta GP, Perk J, Acharyya S, de Candia P, Mittal V, Todorova-Manova K, Gerald WL, Brogi E, Benezra R, Massagué J. ID genes mediate tumor reinitiation during breast cancer lung metastasis. Proceedings of the National Academy of Sciences of the United States of America. 104: 19506-11. PMID 18048329 DOI: 10.1073/Pnas.0709185104  0.457
2007 Nolan DJ, Ciarrocchi A, Mellick AS, Jaggi JS, Bambino K, Gupta S, Heikamp E, McDevitt MR, Scheinberg DA, Benezra R, Mittal V. Bone marrow-derived endothelial progenitor cells are a major determinant of nascent tumor neovascularization. Genes & Development. 21: 1546-58. PMID 17575055 DOI: 10.1101/Gad.436307  0.42
2007 Singh Jaggi J, Henke E, Seshan SV, Kappel BJ, Chattopadhyay D, May C, McDevitt MR, Nolan D, Mittal V, Benezra R, Scheinberg DA. Selective alpha-particle mediated depletion of tumor vasculature with vascular normalization Plos One. 2. PMID 17342201 DOI: 10.1371/Journal.Pone.0000267  0.355
2007 Mittal V, Nolan DJ. Genomics and proteomics approaches in understanding tumor angiogenesis. Expert Review of Molecular Diagnostics. 7: 133-47. PMID 17331062 DOI: 10.1586/14737159.7.2.133  0.343
2006 Benezra R, Henke E, Ciarrocchi A, Ruzinova M, Solit D, Rosen N, Nolan D, Mittal V, de Candia P. Induction of complete regressions of oncogene-induced breast tumors in mice. Cold Spring Harbor Symposia On Quantitative Biology. 70: 375-81. PMID 16869774 DOI: 10.1101/Sqb.2005.70.006  0.416
2006 Mittal V, Linder ME. Biochemical characterization of RGS14: RGS14 activity towards G-protein alpha subunits is independent of its binding to Rap2A. The Biochemical Journal. 394: 309-15. PMID 16246175 DOI: 10.1042/Bj20051086  0.494
2004 Mittal V, Linder ME. The RGS14 GoLoco domain discriminates among Galphai isoforms. The Journal of Biological Chemistry. 279: 46772-8. PMID 15337739 DOI: 10.1074/Jbc.M407409200  0.513
2004 Hernando E, Nahlé Z, Juan G, Diaz-Rodriguez E, Alaminos M, Hemann M, Michel L, Mittal V, Gerald W, Benezra R, Lowe SW, Cordon-Cardo C. Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control. Nature. 430: 797-802. PMID 15306814 DOI: 10.1038/Nature02820  0.349
2004 Gupta S, Schoer RA, Egan JE, Hannon GJ, Mittal V. Inducible, reversible, and stable RNA interference in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 1927-32. PMID 14762164 DOI: 10.1073/Pnas.0306111101  0.327
2003 Ruzinova MB, Schoer RA, Gerald W, Egan JE, Pandolfi PP, Rafii S, Manova K, Mittal V, Benezra R. Effect of angiogenesis inhibition by Id loss and the contribution of bone-marrow-derived endothelial cells in spontaneous murine tumors. Cancer Cell. 4: 277-89. PMID 14585355 DOI: 10.1016/S1535-6108(03)00240-X  0.415
2002 Mirshahi T, Mittal V, Zhang H, Linder ME, Logothetis DE. Distinct sites on G protein beta gamma subunits regulate different effector functions. The Journal of Biological Chemistry. 277: 36345-50. PMID 12124391 DOI: 10.1074/Jbc.M205359200  0.497
2001 Stolarov J, Chang K, Reiner A, Rodgers L, Hannon GJ, Wigler MH, Mittal V. Design of a retroviral-mediated ecdysone-inducible system and its application to the expression profiling of the PTEN tumor suppressor. Proceedings of the National Academy of Sciences of the United States of America. 98: 13043-8. PMID 11687610 DOI: 10.1073/Pnas.221450598  0.308
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