Carl L. Keen - Publications

Affiliations: 
Nutritional Biology University of California, Davis, Davis, CA 
Area:
Nutrition, Physiology Biology, Biochemistry

294 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Holt RR, Munafo JP, Salmen J, Keen CL, Mistry BS, Whiteley JM, Schmitz HH. Mycelium: A Nutrient-Dense Food To Help Address World Hunger, Promote Health, and Support a Regenerative Food System. Journal of Agricultural and Food Chemistry. PMID 38054424 DOI: 10.1021/acs.jafc.3c03307  0.553
2023 Charoenwoodhipong P, Holt RR, Keen CL, Hedayati N, Sato T, Sone T, Hackman RM. The Effect of Hokkaido Red Wines on Vascular Outcomes in Healthy Adult Men: A Pilot Study. Nutrients. 15. PMID 37764837 DOI: 10.3390/nu15184054  0.577
2023 Zuelch ML, Radtke MD, Holt RR, Basu A, Burton-Freeman B, Ferruzzi MG, Li Z, Shay NF, Shukitt-Hale B, Keen CL, Steinberg FM, Hackman RM. Perspective: Challenges and Future Directions in Clinical Research with Nuts and Berries. Advances in Nutrition (Bethesda, Md.). PMID 37536565 DOI: 10.1016/j.advnut.2023.07.010  0.561
2022 Holt RR, Barile D, Wang SC, Munafo JP, Arvik T, Li X, Lee F, Keen CL, Tagkopoulos I, Schmitz HH. Chardonnay Marc as a New Model for Upcycled Co-products in the Food Industry: Concentration of Diverse Natural Products Chemistry for Consumer Health and Sensory Benefits. Journal of Agricultural and Food Chemistry. PMID 36409321 DOI: 10.1021/acs.jafc.2c04519  0.564
2022 Li X, Holt RR, Keen CL, Morse LS, Zivkovic AM, Yiu G, Hackman RM. Potential roles of dietary zeaxanthin and lutein in macular health and function. Nutrition Reviews. PMID 36094616 DOI: 10.1093/nutrit/nuac076  0.593
2021 Li X, Holt RR, Keen CL, Morse LS, Yiu G, Hackman RM. Goji Berry Intake Increases Macular Pigment Optical Density in Healthy Adults: A Randomized Pilot Trial. Nutrients. 13. PMID 34959963 DOI: 10.3390/nu13124409  0.55
2021 Fam VW, Charoenwoodhipong P, Sivamani RK, Holt RR, Keen CL, Hackman RM. Plant-based Foods for Skin Health: A Narrative Review. Journal of the Academy of Nutrition and Dietetics. PMID 34728412 DOI: 10.1016/j.jand.2021.10.024  0.566
2021 Al-Dashti YA, Holt RR, Keen CL, Hackman RM. Date Palm Fruit (): Effects on Vascular Health and Future Research Directions. International Journal of Molecular Sciences. 22. PMID 33925062 DOI: 10.3390/ijms22094665  0.582
2020 Fam VW, Holt RR, Keen CL, Sivamani RK, Hackman RM. Prospective Evaluation of Mango Fruit Intake on Facial Wrinkles and Erythema in Postmenopausal Women: A Randomized Clinical Pilot Study. Nutrients. 12. PMID 33158079 DOI: 10.3390/nu12113381  0.552
2020 Sowell KD, Holt RR, Uriu-Adams JY, Chambers CD, Coles CD, Kable JA, Yevtushok L, Zymak-Zakutnya N, Wertelecki W, Keen CL. Altered Maternal Plasma Fatty Acid Composition by Alcohol Consumption and Smoking during Pregnancy and Associations with Fetal Alcohol Spectrum Disorders. Journal of the American College of Nutrition. 39: 249-260. PMID 32240041 DOI: 10.1080/07315724.2020.1737984  0.565
2020 Varkey A, Devi S, Mukhopadhyay A, Kamat NG, Pauline M, Dharmar M, Holt RR, Allen LH, Thomas T, Keen CL, Kurpad AV. Metabolome and microbiome alterations related to short-term feeding of a micronutrient-fortified, high-quality legume protein-based food product to stunted school age children: A randomized controlled pilot trial. Clinical Nutrition (Edinburgh, Scotland). PMID 32139110 DOI: 10.1016/J.Clnu.2020.02.018  0.59
2020 Chowanadisai W, Hart MD, Strong MD, Graham DM, Rucker RB, Smith BJ, Keen CL, Messerli MA. Genetic and Genomic Advances in Developmental Models: Applications for Nutrition Research. Advances in Nutrition (Bethesda, Md.). PMID 32135011 DOI: 10.1093/Advances/Nmaa022  0.325
2020 Devi S, Varkey A, Dharmar M, Holt RR, Allen LH, Sheshshayee MS, Preston T, Keen CL, Kurpad AV. Amino Acid Digestibility of Extruded Chickpea and Yellow Pea Protein is High and Comparable in Moderately Stunted South Indian Children with Use of a Dual Stable Isotope Tracer Method. The Journal of Nutrition. PMID 32006007 DOI: 10.1093/Jn/Nxaa004  0.571
2020 Holt RR, Zuelch ML, Charoenwoodhipong P, Al-Dashti YA, Hackman RM, Keen CL. Effects of short-term consumption of strawberry powder on select parameters of vascular health in adolescent males. Food & Function. PMID 31942892 DOI: 10.1039/C9Fo01844A  0.617
2020 Padhi E, Holt R, Slupsky C, Keen C. A Crossover Study of Freeze-Dried Strawberry Powder on Microvascular Function, Gut Microbiota, and Metabolic Phenotype in Overweight or Obese Postmenopausal Women Current Developments in Nutrition. 4: 447-447. DOI: 10.1093/cdn/nzaa045_080  0.573
2020 Li X, Holt R, Keen C, Hackman R. Effects of Goji Berry Intake on Macular Pigment Optical Density and Skin Carotenoids in Healthy Adults Current Developments in Nutrition. 4: 119-119. DOI: 10.1093/cdn/nzaa041_023  0.542
2020 Fam V, Sivamani R, Holt R, Keen C, Hackman R. Mango Intake Affects Skin Wrinkles in Postmenopausal Women Current Developments in Nutrition. 4: 104-104. DOI: 10.1093/cdn/nzaa041_008  0.544
2019 Sowell K, Holt R, Uriu-Adams J, Chambers C, Coles C, Kable J, Yevtushok L, Zymak-Zakutnya N, Wertelecki W, Keen C. Alcohol Consumption and Smoking During Pregnancy Alters Maternal Plasma Fatty Acid Composition: Association with Fetal Alcohol Spectrum Disorders (P11-028-19). Current Developments in Nutrition. 3. PMID 31224760 DOI: 10.1093/cdn/nzz048.P11-028-19  0.517
2019 Al-Dashti YA, Holt RR, Carson JG, Keen CL, Hackman RM. Effects of Short-Term Dried Plum (Prune) Intake on Markers of Bone Resorption and Vascular Function in Healthy Postmenopausal Women: A Randomized Crossover Trial. Journal of Medicinal Food. PMID 31194598 DOI: 10.1089/Jmf.2018.0209  0.596
2019 Borkowski K, Yim SJ, Holt RR, Hackman RM, Keen CL, Newman JW, Shearer GC. Walnuts change lipoprotein composition suppressing TNFα-stimulated cytokine production by diabetic adipocyte. The Journal of Nutritional Biochemistry. 68: 51-58. PMID 31030167 DOI: 10.1016/J.Jnutbio.2019.03.004  0.59
2019 Dressendorfer RH, Wade CE, Keen CL, Scaff JH. Plasma Mineral Levels in Marathon Runners During a 20-Day Road Race. The Physician and Sportsmedicine. 10: 113-118. PMID 29261062 DOI: 10.1080/00913847.1982.11947250  0.347
2019 Hannum SM, Schmitz HH, Keen CL. Chocolate: A Heart-healthy Food? Show Me the Science! Nutrition Today. 37: 103-109. PMID 12131785 DOI: 10.1097/00017285-200205000-00004  0.356
2019 Holt R, Hast A, Keen C. Analysis of the Impact of Dietary Nitrate Intake on Vascular Function in Physically Active Adults (P06-101-19) Current Developments in Nutrition. 3. DOI: 10.1093/cdn/nzz031.P06-101-19  0.562
2018 Al-Dashti YA, Holt RR, Stebbins CL, Keen CL, Hackman RM. Dietary Flavanols: A Review of Select Effects on Vascular Function, Blood Pressure, and Exercise Performance. Journal of the American College of Nutrition. 1-15. PMID 29718795 DOI: 10.1080/07315724.2018.1451788  0.606
2016 Medici V, Kieffer DA, Shibata NM, Chima H, Kim K, Canovas A, Medrano JF, Islas-Trejo AD, Kharbanda KK, Olson K, Su RJ, Islam MS, Syed R, Keen CL, Miller AY, et al. Wilson Disease: epigenetic effects of choline supplementation on phenotype and clinical course in a mouse model. Epigenetics. 0. PMID 27611852 DOI: 10.1080/15592294.2016.1231289  0.329
2016 Djurica D, Holt RR, Ren J, Shindel AW, Hackman RM, Keen CL. Effects of a dietary strawberry powder on parameters of vascular health in adolescent males. The British Journal of Nutrition. 116: 639-47. PMID 27464461 DOI: 10.1017/S0007114516002348  0.635
2016 Peters AJ, Dressendorfer RH, Rimar J, Keen CL. Diets of Endurance Runners Competing in a 20-Day Road Race. The Physician and Sportsmedicine. 14: 63-70. PMID 27441437 DOI: 10.1080/00913847.1986.11709123  0.352
2016 Ottaviani JI, Borges G, Momma TY, Spencer JP, Keen CL, Crozier A, Schroeter H. The metabolome of [2-(14)C](-)-epicatechin in humans: implications for the assessment of efficacy, safety, and mechanisms of action of polyphenolic bioactives. Scientific Reports. 6: 29034. PMID 27363516 DOI: 10.1038/Srep29034  0.36
2016 Borchers AT, Keen CL, Gershwin ME. The Basis of Structure/Function Claims of Nutraceuticals. Clinical Reviews in Allergy & Immunology. PMID 27122022 DOI: 10.1007/S12016-016-8536-9  0.318
2016 Lesser MNR, Park J, Gedestad MD, Keen CL, Uriu- Adams JY, Lanoue L. Examining the potential benefits of (-)-epicatechin, (+)-catechin, and rutin on maternal and offspring cardiovascular outcomes in LDLr-/- mice exposed to an atherogenic environment during early development Functional Foods in Health and Disease. 6: 173. DOI: 10.31989/Ffhd.V6I4.232  0.377
2016 Djurica D, Ren J, Holt RR, Feng X, Carlson CR, Shindel AW, Keen CL, Hackman RM. A single intake of a resveratrol-arginine conjugate improves microvascular function compared to trans-resveratrol in postmenopausal women Pharmanutrition. 4: 132-138. DOI: 10.1016/J.Phanu.2016.05.002  0.618
2015 Lesser MNR, Keen CL, Lanoue L. Reproductive and developmental outcomes, and influence on maternal and offspring tissue mineral concentrations, of (-)-epicatechin, (+)-catechin, and rutin ingestion prior to, and during pregnancy and lactation in C57BL/6J mice. Toxicology Reports. 2: 443-449. PMID 28962380 DOI: 10.1016/J.Toxrep.2015.01.003  0.33
2015 Sowell KD, Keen CL, Uriu-Adams JY. Vitamin D and Reproduction: From Gametes to Childhood. Healthcare (Basel, Switzerland). 3: 1097-120. PMID 27417816 DOI: 10.3390/Healthcare3041097  0.304
2015 Ottaviani JI, Balz M, Kimball J, Ensunsa JL, Fong R, Momma TY, Kwik-Uribe C, Schroeter H, Keen CL. Safety and efficacy of cocoa flavanol intake in healthy adults: a randomized, controlled, double-masked trial. The American Journal of Clinical Nutrition. PMID 26537937 DOI: 10.3945/Ajcn.115.116178  0.329
2015 Holt RR, Yim SJ, Shearer GC, Hackman RM, Djurica D, Newman JW, Shindel AW, Keen CL. Effects of short-term walnut consumption on human microvascular function and its relationship to plasma epoxide content. The Journal of Nutritional Biochemistry. PMID 26396054 DOI: 10.1016/J.Jnutbio.2015.07.012  0.63
2015 Nguyen LM, Scherr RE, Linnell JD, Ermakov IV, Gellermann W, Jahns L, Keen CL, Miyamoto S, Steinberg FM, Young HM, Zidenberg-Cherr S. Evaluating the relationship between plasma and skin carotenoids and reported dietary intake in elementary school children to assess fruit and vegetable intake. Archives of Biochemistry and Biophysics. 572: 73-80. PMID 25765187 DOI: 10.1016/J.Abb.2015.02.015  0.313
2015 Dwyer JT, Wiemer KL, Dary O, Keen CL, King JC, Miller KB, Philbert MA, Tarasuk V, Taylor CL, Gaine PC, Jarvis AB, Bailey RL. Fortification and health: challenges and opportunities. Advances in Nutrition (Bethesda, Md.). 6: 124-31. PMID 25593151 DOI: 10.3945/An.114.007443  0.367
2014 Hackman RM, Aggarwal BB, Applebaum RS, deVere White RW, Dubick MA, Heber D, Ito T, Johnson GH, Keen CL, Winters BL, Stohs SJ. Forecasting nutrition research in 2020. Journal of the American College of Nutrition. 33: 340-6. PMID 25144361 DOI: 10.1080/07315724.2014.943113  0.335
2014 Medici V, Shibata NM, Kharbanda KK, Islam MS, Keen CL, Kim K, Tillman B, French SW, Halsted CH, LaSalle JM. Maternal choline modifies fetal liver copper, gene expression, DNA methylation, and neonatal growth in the tx-j mouse model of Wilson disease. Epigenetics : Official Journal of the Dna Methylation Society. 9: 286-96. PMID 24220304 DOI: 10.4161/Epi.27110  0.335
2013 Keen CL, Reinstein NH, Goudey-Lefevre J, Lefevre M, Lönnerdal B, Schneeman BO, Hurley LS. Effect of dietary copper and zinc levels on tissue copper, zinc, and iron in male rats. Biological Trace Element Research. 8: 123-36. PMID 24257872 DOI: 10.1007/Bf02917466  0.352
2013 Uriu-Adams JY, Obican SG, Keen CL. Vitamin D and maternal and child health: overview and implications for dietary requirements. Birth Defects Research. Part C, Embryo Today : Reviews. 99: 24-44. PMID 23723170 DOI: 10.1002/Bdrc.21031  0.301
2013 Zunino SJ, Storms DH, Newman JW, Pedersen TL, Keen CL, Ducore JM. Oral or parenteral administration of curcumin does not prevent the growth of high-risk t(4;11) acute lymphoblastic leukemia cells engrafted into a NOD/SCID mouse model. International Journal of Oncology. 42: 741-8. PMID 23232667 DOI: 10.3892/Ijo.2012.1734  0.32
2012 Zunino SJ, Storms DH, Newman JW, Pedersen TL, Keen CL, Ducore JM. Dietary resveratrol does not delay engraftment, sensitize to vincristine or inhibit growth of high-risk acute lymphoblastic leukemia cells in NOD/SCID mice. International Journal of Oncology. 41: 2207-12. PMID 23041950 DOI: 10.3892/Ijo.2012.1650  0.345
2012 Holt RR, Heiss C, Kelm M, Keen CL. The potential of flavanol and procyanidin intake to influence age-related vascular disease. Journal of Nutrition in Gerontology and Geriatrics. 31: 290-323. PMID 22888843 DOI: 10.1080/21551197.2012.702541  0.637
2012 Ottaviani JI, Kwik-Uribe C, Keen CL, Schroeter H. Intake of dietary procyanidins does not contribute to the pool of circulating flavanols in humans. The American Journal of Clinical Nutrition. 95: 851-8. PMID 22378733 DOI: 10.3945/Ajcn.111.028340  0.356
2012 Hills JI, Golub MS, Bettendorff L, Keen CL. The effect of thiamin tetrahydrofurfuryl disulfide on behavior of juvenile DBA/2J mice. Neurotoxicology and Teratology. 34: 242-52. PMID 21816221 DOI: 10.1016/J.Ntt.2011.07.006  0.303
2011 Mackenzie GG, Salvador GA, Romero C, Keen CL, Oteiza PI. A deficit in zinc availability can cause alterations in tubulin thiol redox status in cultured neurons and in the developing fetal rat brain. Free Radical Biology & Medicine. 51: 480-9. PMID 21600978 DOI: 10.1016/J.Freeradbiomed.2011.04.028  0.318
2011 Ottaviani JI, Momma TY, Heiss C, Kwik-Uribe C, Schroeter H, Keen CL. The stereochemical configuration of flavanols influences the level and metabolism of flavanols in humans and their biological activity in vivo. Free Radical Biology & Medicine. 50: 237-44. PMID 21074608 DOI: 10.1016/J.Freeradbiomed.2010.11.005  0.396
2011 Shenoy SF, Chowanadisai W, Sharman E, Keen CL, Liu J, Rucker RB. Biofactors in food promote health by enhancing mitochondrial function California Agriculture. 65: 141-147. DOI: 10.3733/Ca.V065N03P141  0.712
2011 Chowanadisai W, Shenoy SF, Sharman E, Keen CL, Liu J, Rucker RB. Well-functioning cell mitochondria promote good health California Agriculture. 65: 136-140. DOI: 10.3733/Ca.V065N03P136  0.713
2011 Barnes J, Holt R, Schramm D, Waters A, Painter J, Keen C. Raisin Consumption May Lower Circulating Oxidized LDL Levels, Potentially Decreasing the Risk for Coronary Artery Disease Journal of the American Dietetic Association. 111: A46. DOI: 10.1016/J.Jada.2011.06.162  0.567
2010 Chambers A, Krewski D, Birkett N, Plunkett L, Hertzberg R, Danzeisen R, Aggett PJ, Starr TB, Baker S, Dourson M, Jones P, Keen CL, Meek B, Schoeny R, Slob W. An exposure-response curve for copper excess and deficiency. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 13: 546-78. PMID 21170809 DOI: 10.1080/10937404.2010.538657  0.329
2010 Schroeter H, Heiss C, Spencer JP, Keen CL, Lupton JR, Schmitz HH. Recommending flavanols and procyanidins for cardiovascular health: current knowledge and future needs. Molecular Aspects of Medicine. 31: 546-57. PMID 20854838 DOI: 10.1016/J.Mam.2010.09.008  0.328
2010 Heiss C, Keen CL, Kelm M. Flavanols and cardiovascular disease prevention. European Heart Journal. 31: 2583-92. PMID 20852295 DOI: 10.1093/Eurheartj/Ehq332  0.371
2010 Shenoy SF, Kazaks AG, Holt RR, Chen HJ, Winters BL, Khoo CS, Poston WS, Haddock CK, Reeves RS, Foreyt JP, Gershwin ME, Keen CL. The use of a commercial vegetable juice as a practical means to increase vegetable intake: a randomized controlled trial. Nutrition Journal. 9: 38. PMID 20849620 DOI: 10.1186/1475-2891-9-38  0.795
2010 Uriu-Adams JY, Keen CL. Zinc and reproduction: effects of zinc deficiency on prenatal and early postnatal development. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 89: 313-25. PMID 20803691 DOI: 10.1002/Bdrb.20264  0.334
2010 Heiss C, Jahn S, Taylor M, Real WM, Angeli FS, Wong ML, Amabile N, Prasad M, Rassaf T, Ottaviani JI, Mihardja S, Keen CL, Springer ML, Boyle A, Grossman W, et al. Improvement of endothelial function with dietary flavanols is associated with mobilization of circulating angiogenic cells in patients with coronary artery disease. Journal of the American College of Cardiology. 56: 218-24. PMID 20620742 DOI: 10.1016/J.Jacc.2010.03.039  0.318
2010 Hanna LA, Clegg MS, Ellis-Hutchings RG, Niles BJ, Keen CL. The influence of gestational zinc deficiency on the fetal insulin-like growth factor axis in the rat. Experimental Biology and Medicine (Maywood, N.J.). 235: 206-14. PMID 20404036 DOI: 10.1258/Ebm.2009.009018  0.783
2010 Lanoue L, Green KK, Kwik-Uribe C, Keen CL. Dietary factors and the risk for acute infant leukemia: evaluating the effects of cocoa-derived flavanols on DNA topoisomerase activity. Experimental Biology and Medicine (Maywood, N.J.). 235: 77-89. PMID 20404022 DOI: 10.1258/Ebm.2009.009184  0.326
2010 Gershwin ME, Borchers AT, Keen CL, Hendler S, Hagie F, Greenwood MR. Public safety and dietary supplementation. Annals of the New York Academy of Sciences. 1190: 104-17. PMID 20388141 DOI: 10.1111/J.1749-6632.2009.05270.X  0.317
2010 Keen CL, Uriu-Adams JY, Skalny A, Grabeklis A, Grabeklis S, Green K, Yevtushok L, Wertelecki WW, Chambers CD. The plausibility of maternal nutritional status being a contributing factor to the risk for fetal alcohol spectrum disorders: the potential influence of zinc status as an example. Biofactors (Oxford, England). 36: 125-35. PMID 20333752 DOI: 10.1002/Biof.89  0.301
2010 Kalgaonkar S, Nishioka H, Gross HB, Fujii H, Keen CL, Hackman RM. Bioactivity of a flavanol-rich lychee fruit extract in adipocytes and its effects on oxidant defense and indices of metabolic syndrome in animal models. Phytotherapy Research : Ptr. 24: 1223-8. PMID 20309950 DOI: 10.1002/Ptr.3137  0.361
2010 Uriu-Adams JY, Scherr RE, Lanoue L, Keen CL. Influence of copper on early development: prenatal and postnatal considerations. Biofactors (Oxford, England). 36: 136-52. PMID 20232410 DOI: 10.1002/Biof.85  0.308
2010 Shenoy SF, Poston WS, Reeves RS, Kazaks AG, Holt RR, Keen CL, Chen HJ, Haddock CK, Winters BL, Khoo CS, Foreyt JP. Weight loss in individuals with metabolic syndrome given DASH diet counseling when provided a low sodium vegetable juice: a randomized controlled trial. Nutrition Journal. 9: 8. PMID 20178625 DOI: 10.1186/1475-2891-9-8  0.771
2010 Kalgaonkar S, Gross HB, Yokoyama W, Keen CL. Effects of a flavonol-rich diet on select cardiovascular parameters in a Golden Syrian hamster model. Journal of Medicinal Food. 13: 108-15. PMID 20136443 DOI: 10.1089/Jmf.2008.0295  0.361
2009 Williamson G, Sies H, Heber D, Keen CL, Macdonald IA, Actis-Goretta L, Actis-Gorreta L, Momma TY, Ottaviani JI, Holt RR, Schroeter H, Heiss C. Functional foods for health promotion: state-of-the-science on dietary flavonoids. Extended abstracts from the 12th Annual Conference on Functional Foods for Health Promotion, April 2009. Nutrition Reviews. 67: 736-43. PMID 19941619 DOI: 10.1111/J.1753-4887.2009.00257.X  0.622
2009 Ellis-Hutchings RG, Cherr GN, Hanna LA, Keen CL. The effects of marginal maternal vitamin A status on penta-brominated diphenyl ether mixture-induced alterations in maternal and conceptal vitamin A and fetal development in the Sprague Dawley rat. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 86: 48-57. PMID 19145591 DOI: 10.1002/Bdrb.20181  0.724
2008 Selmi C, Cocchi CA, Lanfredini M, Keen CL, Gershwin ME. Chocolate at heart: the anti-inflammatory impact of cocoa flavanols. Molecular Nutrition & Food Research. 52: 1340-8. PMID 18991246 DOI: 10.1002/Mnfr.200700435  0.335
2008 Devaraj S, Wang-Polagruto J, Polagruto J, Keen CL, Jialal I. High-fat, energy-dense, fast-food-style breakfast results in an increase in oxidative stress in metabolic syndrome. Metabolism: Clinical and Experimental. 57: 867-70. PMID 18502272 DOI: 10.1016/J.Metabol.2008.02.016  0.796
2008 Schnorr O, Brossette T, Momma TY, Kleinbongard P, Keen CL, Schroeter H, Sies H. Cocoa flavanols lower vascular arginase activity in human endothelial cells in vitro and in erythrocytes in vivo. Archives of Biochemistry and Biophysics. 476: 211-5. PMID 18348861 DOI: 10.1016/J.Abb.2008.02.040  0.33
2008 Lopez V, Keen CL, Lanoue L. Prenatal zinc deficiency: influence on heart morphology and distribution of key heart proteins in a rat model. Biological Trace Element Research. 122: 238-55. PMID 18224284 DOI: 10.1007/S12011-007-8079-2  0.306
2008 Niles BJ, Clegg MS, Hanna LA, Chou SS, Momma TY, Hong H, Keen CL. Zinc deficiency-induced iron accumulation, a consequence of alterations in iron regulatory protein-binding activity, iron transporters, and iron storage proteins. The Journal of Biological Chemistry. 283: 5168-77. PMID 18073202 DOI: 10.1074/Jbc.M709043200  0.774
2008 Shenoy S, Kazaks A, Holt R, Keen C. Vegetable Juice Is an Effective and Acceptable Way to Meet Dash Vegetable Recommendations Journal of the American Dietetic Association. 108: A104. DOI: 10.1016/J.Jada.2008.06.303  0.79
2008 Hackman RM, Polagruto JA, Zhu QY, Sun B, Fujii H, Keen CL. Flavanols: Digestion, absorption and bioactivity Phytochemistry Reviews. 7: 195-208. DOI: 10.1007/S11101-007-9070-4  0.799
2007 Polagruto JA, Gross HB, Kamangar F, Kosuna K, Sun B, Fujii H, Keen CL, Hackman RM. Platelet reactivity in male smokers following the acute consumption of a flavanol-rich grapeseed extract. Journal of Medicinal Food. 10: 725-30. PMID 18158849 DOI: 10.1089/Jmf.2007.402  0.809
2007 Shenoy SF, Keen CL, Kalgaonkar S, Polagruto JA. Effects of grape seed extract consumption on platelet function in postmenopausal women. Thrombosis Research. 121: 431-2. PMID 17950783 DOI: 10.1016/J.Thromres.2007.09.004  0.759
2007 Erdman JW, Balentine D, Arab L, Beecher G, Dwyer JT, Folts J, Harnly J, Hollman P, Keen CL, Mazza G, Messina M, Scalbert A, Vita J, Williamson G, Burrowes J. Flavonoids and heart health: proceedings of the ILSI North America Flavonoids Workshop, May 31-June 1, 2005, Washington, DC. The Journal of Nutrition. 137: 718S-737S. PMID 17311968 DOI: 10.1093/Jn/137.3.718S  0.303
2007 Graham TW, Giri SN, Daels PF, Cullor JS, Keen CL, Thurmond MC, Dellinger JD, Stabenfeldt GH, Osburn BI. Associations among prostaglandin F2alpha, plasma zinc, copper and iron concentrations and fetal loss in cows and mares. Theriogenology. 44: 379-90. PMID 16727737 DOI: 10.1016/0093-691X(95)00192-B  0.315
2007 Hanna LA, Clegg MS, Ellis‐Hutchings RG, Niles BJ, Keen CL. Zinc deficiency induced disruption in the fetal and maternal rat insulin‐like growth factor axis The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A719-C  0.747
2006 Polagruto JA, Wang-Polagruto JF, Braun MM, Lee L, Kwik-Uribe C, Keen CL. Cocoa flavanol-enriched snack bars containing phytosterols effectively lower total and low-density lipoprotein cholesterol levels. Journal of the American Dietetic Association. 106: 1804-13. PMID 17081832 DOI: 10.1016/J.Jada.2006.08.012  0.783
2006 Holt RR, Actis-Goretta L, Momma TY, Keen CL. Dietary flavanols and platelet reactivity. Journal of Cardiovascular Pharmacology. 47: S187-96; discussion . PMID 16794457 DOI: 10.1097/00005344-200606001-00014  0.623
2006 Wang-Polagruto JF, Villablanca AC, Polagruto JA, Lee L, Holt RR, Schrader HR, Ensunsa JL, Steinberg FM, Schmitz HH, Keen CL. Chronic consumption of flavanol-rich cocoa improves endothelial function and decreases vascular cell adhesion molecule in hypercholesterolemic postmenopausal women. Journal of Cardiovascular Pharmacology. 47: S177-86; discussion . PMID 16794456 DOI: 10.1097/00005344-200606001-00013  0.786
2006 Davis PA, Polagruto JA, Valacchi G, Phung A, Soucek K, Keen CL, Gershwin ME. Effect of apple extracts on NF-kappaB activation in human umbilical vein endothelial cells. Experimental Biology and Medicine (Maywood, N.J.). 231: 594-8. PMID 16636308 DOI: 10.1177/153537020623100514  0.786
2006 Ellis-Hutchings RG, Cherr GN, Hanna LA, Keen CL. Polybrominated diphenyl ether (PBDE)-induced alterations in vitamin A and thyroid hormone concentrations in the rat during lactation and early postnatal development. Toxicology and Applied Pharmacology. 215: 135-45. PMID 16580039 DOI: 10.1016/J.Taap.2006.02.008  0.721
2006 Schroeter H, Heiss C, Balzer J, Kleinbongard P, Keen CL, Hollenberg NK, Sies H, Kwik-Uribe C, Schmitz HH, Kelm M. (-)-Epicatechin mediates beneficial effects of flavanol-rich cocoa on vascular function in humans. Proceedings of the National Academy of Sciences of the United States of America. 103: 1024-9. PMID 16418281 DOI: 10.1073/Pnas.0510168103  0.38
2006 Beckers-Trapp ME, Lanoue L, Keen CL, Rucker RB, Uriu-Adams JY. Abnormal development and increased 3-nitrotyrosine in copper-deficient mouse embryos. Free Radical Biology & Medicine. 40: 35-44. PMID 16337877 DOI: 10.1016/J.Freeradbiomed.2005.08.020  0.328
2006 Mackenzie GG, Zago MP, Erlejman AG, Aimo L, Keen CL, Oteiza PI. alpha-Lipoic acid and N-acetyl cysteine prevent zinc deficiency-induced activation of NF-kappaB and AP-1 transcription factors in human neuroblastoma IMR-32 cells. Free Radical Research. 40: 75-84. PMID 16298762 DOI: 10.1080/10715760500312305  0.316
2006 Polagruto J, Hackman R, Keen C, Kosuna K, Fujii H, Sun B, Stern J. Flavanol-Rich Extract Decreases Platelet Reactivity in Male Smokers Journal of the American Dietetic Association. 106: A13. DOI: 10.1016/J.Jada.2006.05.034  0.761
2005 Zago MP, Mackenzie GG, Adamo AM, Keen CL, Oteiza PI. Differential modulation of MAP kinases by zinc deficiency in IMR-32 cells: role of H(2)O(2). Antioxidants & Redox Signaling. 7: 1773-82. PMID 16356139 DOI: 10.1089/Ars.2005.7.1773  0.301
2005 Clegg MS, Hanna LA, Niles BJ, Momma TY, Keen CL. Zinc deficiency-induced cell death. Iubmb Life. 57: 661-9. PMID 16223705 DOI: 10.1080/15216540500264554  0.751
2005 Zhu QY, Schramm DD, Gross HB, Holt RR, Kim SH, Yamaguchi T, Kwik-Uribe CL, Keen CL. Influence of cocoa flavanols and procyanidins on free radical-induced human erythrocyte hemolysis. Clinical & Developmental Immunology. 12: 27-34. PMID 15712596 DOI: 10.1080/17402520512331329514  0.605
2005 Fraga CG, Actis-Goretta L, Ottaviani JI, Carrasquedo F, Lotito SB, Lazarus S, Schmitz HH, Keen CL. Regular consumption of a flavanol-rich chocolate can improve oxidant stress in young soccer players. Clinical & Developmental Immunology. 12: 11-7. PMID 15712594 DOI: 10.1080/10446670410001722159  0.369
2005 Pearson DA, Holt RR, Rein D, Paglieroni T, Schmitz HH, Keen CL. Flavanols and platelet reactivity. Clinical & Developmental Immunology. 12: 1-9. PMID 15712593 DOI: 10.1080/10446670410001722140  0.591
2005 Keen CL, Holt RR, Oteiza PI, Fraga CG, Schmitz HH. Cocoa antioxidants and cardiovascular health. The American Journal of Clinical Nutrition. 81: 298S-303S. PMID 15640494 DOI: 10.1093/Ajcn/81.1.298S  0.628
2004 Ensunsa JL, Symons JD, Lanoue L, Schrader HR, Keen CL. Reducing arginase activity via dietary manganese deficiency enhances endothelium-dependent vasorelaxation of rat aorta. Experimental Biology and Medicine (Maywood, N.J.). 229: 1143-53. PMID 15564441 DOI: 10.1177/153537020422901109  0.326
2004 Cui CT, Uriu-Adams JY, Tchaparian EH, Keen CL, Rucker RB. Metavanadate causes cellular accumulation of copper and decreased lysyl oxidase activity. Toxicology and Applied Pharmacology. 199: 35-43. PMID 15289088 DOI: 10.1016/J.Taap.2004.03.007  0.352
2004 Chou SS, Clegg MS, Momma TY, Niles BJ, Duffy JY, Daston GP, Keen CL. Alterations in protein kinase C activity and processing during zinc-deficiency-induced cell death. The Biochemical Journal. 383: 63-71. PMID 15198639 DOI: 10.1042/Bj20040074  0.773
2004 Turnlund JR, Jacob RA, Keen CL, Strain JJ, Kelley DS, Domek JM, Keyes WR, Ensunsa JL, Lykkesfeldt J, Coulter J. Long-term high copper intake: effects on indexes of copper status, antioxidant status, and immune function in young men. The American Journal of Clinical Nutrition. 79: 1037-44. PMID 15159234 DOI: 10.1093/Ajcn/79.6.1037  0.305
2004 Duffy JY, Overmann GJ, Keen CL, Clegg MS, Daston GP. Cardiac abnormalities induced by zinc deficiency are associated with alterations in the expression of genes regulated by the zinc-finger transcription factor GATA-4. Birth Defects Research. Part B, Developmental and Reproductive Toxicology. 71: 102-9. PMID 15098203 DOI: 10.1002/Bdrb.20004  0.303
2004 Borchers AT, Keen CL, Gershwin ME. Mushrooms, tumors, and immunity: an update. Experimental Biology and Medicine (Maywood, N.J.). 229: 393-406. PMID 15096651 DOI: 10.1177/153537020422900507  0.306
2004 Kenny TP, Keen CL, Jones P, Kung HJ, Schmitz HH, Gershwin ME. Pentameric procyanidins isolated from Theobroma cacao seeds selectively downregulate ErbB2 in human aortic endothelial cells. Experimental Biology and Medicine (Maywood, N.J.). 229: 255-63. PMID 14988518 DOI: 10.1177/153537020422900306  0.31
2003 Polagruto JA, Schramm DD, Wang-Polagruto JF, Lee L, Keen CL. Effects of flavonoid-rich beverages on prostacyclin synthesis in humans and human aortic endothelial cells: association with ex vivo platelet function. Journal of Medicinal Food. 6: 301-8. PMID 14977437 DOI: 10.1089/109662003772519840  0.801
2003 Schroeter H, Holt RR, Orozco TJ, Schmitz HH, Keen CL. Nutrition: milk and absorption of dietary flavanols. Nature. 426: 787-8; discussion 78. PMID 14685225 DOI: 10.1038/426787B  0.63
2003 Golub MS, Germann SL, Keen CL. Developmental aluminum toxicity in mice can be modulated by low concentrations of minerals (Fe, Zn, P, Ca, Mg) in the diet Biological Trace Element Research. 93: 213-225. PMID 12835503 DOI: 10.1385/Bter:93:1-3:213  0.345
2003 Kim SH, Han JH, Zhu QY, Keen CL. Use of vitamins, minerals, and other dietary supplements by 17- and 18-year-old students in Korea. Journal of Medicinal Food. 6: 27-42. PMID 12804018 DOI: 10.1089/109662003765184723  0.348
2003 Schramm DD, Karim M, Schrader HR, Holt RR, Kirkpatrick NJ, Polagruto JA, Ensunsa JL, Schmitz HH, Keen CL. Food effects on the absorption and pharmacokinetics of cocoa flavanols. Life Sciences. 73: 857-69. PMID 12798412 DOI: 10.1016/S0024-3205(03)00373-4  0.789
2003 Keen CL, Clegg MS, Hanna LA, Lanoue L, Rogers JM, Daston GP, Oteiza P, Uriu-Adams JY. The plausibility of micronutrient deficiencies being a significant contributing factor to the occurrence of pregnancy complications. The Journal of Nutrition. 133: 1597S-1605S. PMID 12730474 DOI: 10.1093/Jn/133.5.1597S  0.354
2003 Orozco TJ, Wang JF, Keen CL. Chronic consumption of a flavanol- and procyanindin-rich diet is associated with reduced levels of 8-hydroxy-2'-deoxyguanosine in rat testes. The Journal of Nutritional Biochemistry. 14: 104-10. PMID 12667602 DOI: 10.1016/S0955-2863(02)00273-5  0.57
2003 Schramm DD, Karim M, Schrader HR, Holt RR, Cardetti M, Keen CL. Honey with high levels of antioxidants can provide protection to healthy human subjects. Journal of Agricultural and Food Chemistry. 51: 1732-5. PMID 12617614 DOI: 10.1021/Jf025928K  0.623
2003 Hawk SN, Lanoue L, Keen CL, Kwik-Uribe CL, Rucker RB, Uriu-Adams JY. Copper-deficient rat embryos are characterized by low superoxide dismutase activity and elevated superoxide anions. Biology of Reproduction. 68: 896-903. PMID 12604640 DOI: 10.1095/Biolreprod.102.009167  0.307
2003 Steinberg FM, Bearden MM, Keen CL. Cocoa and chocolate flavonoids: implications for cardiovascular health. Journal of the American Dietetic Association. 103: 215-23. PMID 12589329 DOI: 10.1053/Jada.2003.50028  0.345
2002 Steinberg FM, Holt RR, Schmitz HH, Keen CL. Cocoa procyanidin chain length does not determine ability to protect LDL from oxidation when monomer units are controlled. The Journal of Nutritional Biochemistry. 13: 645-652. PMID 12550061 DOI: 10.1016/S0955-2863(02)00215-2  0.594
2002 Zhu QY, Hackman RM, Ensunsa JL, Holt RR, Keen CL. Antioxidative activities of oolong tea. Journal of Agricultural and Food Chemistry. 50: 6929-34. PMID 12405799 DOI: 10.1021/Jf0206163  0.581
2002 Holt RR, Lazarus SA, Sullards MC, Zhu QY, Schramm DD, Hammerstone JF, Fraga CG, Schmitz HH, Keen CL. Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoa. The American Journal of Clinical Nutrition. 76: 798-804. PMID 12324293 DOI: 10.1093/Ajcn/76.4.798  0.607
2002 Pearson DA, Paglieroni TG, Rein D, Wun T, Schramm DD, Wang JF, Holt RR, Gosselin R, Schmitz HH, Keen CL. The effects of flavanol-rich cocoa and aspirin on ex vivo platelet function. Thrombosis Research. 106: 191-7. PMID 12297125 DOI: 10.1016/S0049-3848(02)00128-7  0.66
2002 Holt RR, Schramm DD, Keen CL, Lazarus SA, Schmitz HH. Chocolate consumption and platelet function. Jama. 287: 2212-3. PMID 11980520 DOI: 10.1001/Jama.287.17.2209  0.565
2002 Zhu QY, Holt RR, Lazarus SA, Orozco TJ, Keen CL. Inhibitory effects of cocoa flavanols and procyanidin oligomers on free radical-induced erythrocyte hemolysis. Experimental Biology and Medicine (Maywood, N.J.). 227: 321-9. PMID 11976402 DOI: 10.1177/153537020222700504  0.601
2002 Zhu QY, Holt RR, Lazarus SA, Ensunsa JL, Hammerstone JF, Schmitz HH, Keen CL. Stability of the flavan-3-ols epicatechin and catechin and related dimeric procyanidins derived from cocoa. Journal of Agricultural and Food Chemistry. 50: 1700-5. PMID 11879061 DOI: 10.1021/Jf011228O  0.534
2002 Kris-Etherton PM, Keen CL. Evidence that the antioxidant flavonoids in tea and cocoa are beneficial for cardiovascular health Current Opinion in Lipidology. 13: 41-49. PMID 11790962 DOI: 10.1097/00041433-200202000-00007  0.374
2002 Keen CL, Holt RR, Polagruto JA, Wang JF, Schmitz HH. Cocoa flavanols and cardiovascular health Phytochemistry Reviews. 1: 231-240. DOI: 10.1023/A:1022519719938  0.789
2002 Kim SH, Keen CL. Vitamin and mineral supplement use among children attending elementary schools in Korea: A survey of eating habits and dietary consequences Nutrition Research. 22: 433-448. DOI: 10.1016/S0271-5317(01)00322-0  0.341
2001 Keen CL. Chocolate: Food as medicine/medicine as food Journal of the American College of Nutrition. 20. PMID 11603654 DOI: 10.1080/07315724.2001.10719181  0.335
2001 Tamura T, Olin KL, Goldenberg RL, Johnston KE, DuBard MB, Keen CL. Plasma extracellular superoxide dismutase activity in healthy pregnant women is not influenced by zinc supplementation Biological Trace Element Research. 80: 107-113. PMID 11437176 DOI: 10.1385/Bter:80:2:107  0.318
2001 Kim SH, Han JH, Keen CL. Vitamin and mineral supplement use by healthy teenagers in Korea: Motivating factors and dietary consequences Nutrition. 17: 373-380. PMID 11377129 DOI: 10.1016/S0899-9007(00)00582-7  0.336
2001 Uriu-Adams JY, Kevin Reece C, Nguyen LK, Horvath BJ, Nair R, Barter RA, Keen CL. Effect of butyl benzyl phthalate on reproduction and zinc metabolism. Toxicology. 159: 55-68. PMID 11250055 DOI: 10.1016/S0300-483X(00)00403-0  0.303
2001 Satre MA, Jessen KA, Clegg MS, Keen CL. Retinol binding protein expression is induced in HepG2 cells by zinc deficiency. Febs Letters. 491: 266-71. PMID 11240140 DOI: 10.1016/S0014-5793(01)02211-6  0.329
2001 Lomer MC, Thompson RP, Commisso J, Keen CL, Powell JJ. Determination of titanium dioxide in foods using inductively coupled plasma optical emission spectrometry. The Analyst. 125: 2339-43. PMID 11219079 DOI: 10.1039/B006285P  0.324
2001 Oteiza PI, Clegg MS, Keen CL. Short-term zinc deficiency affects nuclear factor-kappab nuclear binding activity in rat testes. The Journal of Nutrition. 131: 21-6. PMID 11208933 DOI: 10.1093/Jn/131.1.21  0.361
2001 Schramm DD, Wang JF, Holt RR, Ensunsa JL, Gonsalves JL, Lazarus SA, Schmitz HH, German JB, Keen CL. Chocolate procyanidins decrease the leukotriene-prostacyclin ratio in humans and human aortic endothelial cells. The American Journal of Clinical Nutrition. 73: 36-40. PMID 11124747 DOI: 10.1093/Ajcn/73.1.36  0.761
2000 Kwik-Uribe CL, Gietzen D, German JB, Golub MS, Keen CL. Chronic marginal iron intakes during early development in mice result in persistent changes in dopamine metabolism and myelin composition Journal of Nutrition. 130: 2821-2830. PMID 11053527 DOI: 10.1093/Jn/130.11.2821  0.307
2000 Wang JF, Schramm DD, Holt RR, Ensunsa JL, Fraga CG, Schmitz HH, Keen CL. A dose-response effect from chocolate consumption on plasma epicatechin and oxidative damage. The Journal of Nutrition. 130: 2115S-9S. PMID 10917932 DOI: 10.1093/Jn/130.8.2115S  0.699
2000 Rein D, Lotito S, Holt RR, Keen CL, Schmitz HH, Fraga CG. Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation status. The Journal of Nutrition. 130: 2109S-14S. PMID 10917931 DOI: 10.1093/Jn/130.8.2109S  0.618
2000 Kwik-Uribe CL, Golub MS, Keen CL. Chronic marginal iron intakes during early development in mice alter brain iron concentrations and behavior despite postnatal iron supplementation Journal of Nutrition. 130: 2040-2048. PMID 10917923 DOI: 10.1093/Jn/130.8.2040  0.304
2000 Rein D, Paglieroni TG, Wun T, Pearson DA, Schmitz HH, Gosselin R, Keen CL. Cocoa inhibits platelet activation and function American Journal of Clinical Nutrition. 72: 30-35. PMID 10871557 DOI: 10.1093/Ajcn/72.1.30  0.304
2000 Oteiza PI, Clegg MS, Zago MP, Keen CL. Zinc deficiency induces oxidative stress and AP-1 activation in 3T3 cells. Free Radical Biology & Medicine. 28: 1091-9. PMID 10832070 DOI: 10.1016/S0891-5849(00)00200-8  0.305
2000 Jankowski-Hennig MA, Clegg MS, Daston GP, Rogers JM, Keen CL. Zinc-deficient rat embryos have increased caspase 3-like activity and apoptosis. Biochemical and Biophysical Research Communications. 271: 250-6. PMID 10777711 DOI: 10.1006/Bbrc.2000.2608  0.333
2000 Borchers AT, Keen CL, Stern JS, Gershwin ME. Nutraceuticals: Separating the wheat from the chaff California Agriculture. 54: 26-32. DOI: 10.3733/Ca.V054N05P26  0.363
2000 Zidenberg-Cherr S, Neyman MR, Fechner K, Sutherlin J, Johns M, Lamp C, Garrett C, Keen CL. Nutrition may influence toxicant susceptibility of children and elderly California Agriculture. 54: 19-25. DOI: 10.3733/Ca.V054N05P19  0.338
2000 Keen CL, Zidenberg-Cherr S. What are the best strategies for achieving optimal nutrition? California Agriculture. 54: 12-18. DOI: 10.3733/Ca.V054N05P12  0.382
2000 Borchers AT, Keen CL, Hannum SM, Gershwin ME. Cocoa and Chocolate: Composition, Bioavailability, and Health Implications Journal of Medicinal Food. 3: 77-105. DOI: 10.1089/109662000416285  0.33
2000 Hong KH, Keen CL, Mizuno Y, Johnston KE, Tamura T. Effects of dietary zinc deficiency on homocysteine and folate metabolism in rats Journal of Nutritional Biochemistry. 11: 165-169. DOI: 10.1016/S0955-2863(99)00089-3  0.379
1999 Kim SH, Keen CL. Patterns of vitamin/mineral supplement usage by adolescents attending athletic high schools in Korea International Journal of Sport Nutrition. 9: 391-405. PMID 10660870 DOI: 10.1123/Ijsn.9.4.391  0.325
1999 Rucker RB, Rucker BR, Mitchell AE, Cui CT, Clegg M, Kosonen T, Uriu-Adams JY, Tchaparian EH, Fishman M, Keen CL. Activation of chick tendon lysyl oxidase in response to dietary copper. The Journal of Nutrition. 129: 2143-6. PMID 10573541 DOI: 10.1093/Jn/129.12.2143  0.343
1999 Kwik-Uribe CL, Golub MS, Keen CL. Behavioral consequences of marginal iron deficiency during development in a murine model Neurotoxicology and Teratology. 21: 661-672. PMID 10560773 DOI: 10.1016/S0892-0362(99)00041-0  0.307
1999 Fort DJ, Stover EL, Strong PL, Murray FJ, Keen CL. Chronic feeding of a low boron diet adversely affects reproduction and development in Xenopus laevis. The Journal of Nutrition. 129: 2055-60. PMID 10539784 DOI: 10.1093/Jn/129.11.2055  0.322
1999 Oteiza PI, Adonaylo VN, Keen CL. Cadmium-induced testes oxidative damage in rats can be influenced by dietary zinc intake. Toxicology. 137: 13-22. PMID 10513996 DOI: 10.1016/S0300-483X(99)00067-0  0.372
1999 Kim SH, Keen CL. Influence of dietary carbohydrate on zinc-deficiency-induced changes in oxidative defense mechanisms and tissue oxidative damage in rats Biological Trace Element Research. 70: 81-96. PMID 10493186 DOI: 10.1007/Bf02783851  0.361
1999 Van de Water J, Keen CL, Gershwin ME. The influence of chronic yogurt consumption on immunity. The Journal of Nutrition. 129: 1492S-5S. PMID 10395628 DOI: 10.1093/Jn/129.7.1492S  0.341
1999 Paik HY, Joung H, Lee JY, Lee HK, King JC, Keen CL. Serum extracellular superoxide dismutase activity as an indicator of zinc status in humans. Biological Trace Element Research. 69: 45-57. PMID 10383098 DOI: 10.1007/Bf02783914  0.331
1999 Tamura T, Hong KH, Mizuno Y, Johnston KE, Keen CL. Folate and homocysteine metabolism in copper-deficient rats Biochimica Et Biophysica Acta - General Subjects. 1427: 351-356. PMID 10350650 DOI: 10.1016/S0304-4165(99)00043-4  0.362
1999 Berner L, Childs N, Geiger C, Keen C, King J, McDonald J, Miller S, Murphy S, Schmitz H, Shaw A, Tong P, Weaver C. Food Choices for the 21st Century Journal of Nutraceuticals, Functional & Medical Foods. 1: 89-95. DOI: 10.1300/J133V01N04_07  0.303
1999 Lanoue L, Strong PL, Keen CL. Adverse effects of a low boron environment on the preimplantation development of mouse embryos in vitro Journal of Trace Elements in Experimental Medicine. 12: 235-250. DOI: 10.1002/(Sici)1520-670X(1999)12:3<235::Aid-Jtra7>3.0.Co;2-N  0.317
1998 Lanoue L, Taubeneck MW, Muniz J, Hanna LA, Strong PL, Murray FJ, Nielsen FH, Hunt CD, Keen CL. Assessing the effects of low boron diets on embryonic and fetal development in rodents using in vitro and in vivo model systems. Biological Trace Element Research. 66: 271-98. PMID 10050925 DOI: 10.1007/Bf02783143  0.317
1998 Clegg MS, Donovan SM, Monaco MH, Baly DL, Ensunsa JL, Keen CL. The influence of manganese deficiency on serum IGF-1 and IGF binding proteins in the male rat. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 219: 41-7. PMID 9751221 DOI: 10.3181/00379727-219-44314  0.327
1998 Keen CL, Uriu-Hare JY, Hawk SN, Jankowski MA, Daston GP, Kwik-Uribe CL, Rucker RB. Effect of copper deficiency on prenatal development and pregnancy outcome. The American Journal of Clinical Nutrition. 67: 1003S-1011S. PMID 9587143 DOI: 10.1093/Ajcn/67.5.1003S  0.338
1998 Rucker RB, Kosonen T, Clegg MS, Mitchell AE, Rucker BR, Uriu-Hare JY, Keen CL. Copper, lysyl oxidase, and extracellular matrix protein cross-linking. The American Journal of Clinical Nutrition. 67: 996S-1002S. PMID 9587142 DOI: 10.1093/Ajcn/67.5.996S  0.323
1998 Bui LM, Taubeneck MW, Commisso JF, Uriu-Hare JY, Faber WD, Keen CL. Altered zinc metabolism contributes to the developmental toxicity of 2-ethylhexanoic acid, 2-ethylhexanol and valproic acid. Toxicology. 126: 9-21. PMID 9585088 DOI: 10.1016/S0300-483X(97)00171-6  0.358
1998 Buchman AL, Keen C, Commisso J, Killip D, Ou CN, Rognerud CL, Dennis K, Dunn JK. The effect of a marathon run on plasma and urine mineral and metal concentrations. Journal of the American College of Nutrition. 17: 124-7. PMID 9550455 DOI: 10.1080/07315724.1998.10718737  0.302
1998 Bell RC, Sakanashi TM, Keen CL, Finegood DT. High fructose intake significantly reduces kidney copper concentrations in diabetic, islet transplanted rats. Biological Trace Element Research. 61: 137-49. PMID 9517486 DOI: 10.1007/Bf02784026  0.34
1998 Duffy JY, Baines D, Overmann GJ, Keen CL, Daston GP. Repeated administration of alpha-hederin results in alterations in maternal zinc status and adverse developmental outcome in the rat. Teratology. 56: 327-34. PMID 9451757 DOI: 10.1002/(Sici)1096-9926(199711)56:5<327::Aid-Tera6>3.0.Co;2-U  0.309
1997 Hanna LA, Peters JM, Wiley LM, Zidenberg-Cherr S, Keen CL. Enhancing effect of maternal zinc deficiency and 137Cs γ- irradiation on the frequency of fetal malformations in mice Teratogenesis Carcinogenesis and Mutagenesis. 17: 127-137. PMID 9436262 DOI: 10.1002/(Sici)1520-6866(1997)17:3<127::Aid-Tcm4>3.0.Co;2-J  0.34
1997 Aldrian PS, Keen CL, Lönnerdal B, Dewey KG. Effects of coffee consumption on iron, zinc and copper status in nonpregnant and pregnant Sprague-Dawley rats International Journal of Food Sciences and Nutrition. 48: 177-189. PMID 9205593 DOI: 10.3109/09637489709012591  0.334
1997 Sakanashi TM, Rogers JM, Fu SS, Connelly LE, Keen CL. Influence of maternal folate status on the developmental toxicity of methanol in the CD-1 mouse. Teratology. 54: 198-206. PMID 9122889 DOI: 10.1002/(Sici)1096-9926(199610)54:4<198::Aid-Tera4>3.0.Co;2-Y  0.346
1997 Turnlund JR, Scott KC, Peiffer GL, Jang AM, Keyes WR, Keen CL, Sakanashi TM. Copper status of young men consuming a low-copper diet. The American Journal of Clinical Nutrition. 65: 72-8. PMID 8988916 DOI: 10.1093/Ajcn/65.1.72  0.326
1997 Fu SS, Sakanashi TM, Rogers JM, Hong KH, Keen CL. Influence of dietary folic acid on the developmental toxicity of methanol and the frequency of chromosomal breakage in the CD-1 mouse. Reproductive Toxicology (Elmsford, N.Y.). 10: 455-63. PMID 8946559 DOI: 10.1016/S0890-6238(96)00132-3  0.369
1997 Keen CL, Taubeneck MW, Zidenberg-Cherr S, Daston GP, Rogers JM. Toxicant exposure and trace element metabolism in pregnancy Environmental Toxicology and Pharmacology. 4: 301-308. DOI: 10.1016/S1382-6689(97)10028-X  0.321
1996 Miller GD, Keen CL, Stern JS, Uriu-Hare JY. Copper absorption, endogenous excretion, and distribution in Sprague-Dawley and lean (Fa/Fa) Zucker rats. Biological Trace Element Research. 53: 261-79. PMID 8862755 DOI: 10.1007/Bf02784562  0.308
1996 Oteiza PL, Olin KL, Fraga CG, Keen CL. Oxidant defense systems in testes from zinc-deficient rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 213: 85-91. PMID 8820828 DOI: 10.3181/00379727-213-44040  0.381
1996 Golub MS, Keen CL, Gershwin ME, Styne DM, Takeuchi PT, Ontell F, Walter RM, Hendrickx AG. Adolescent growth and maturation in zinc-deprived rhesus monkeys American Journal of Clinical Nutrition. 64: 274-282. PMID 8780334 DOI: 10.1093/Ajcn/64.3.274  0.338
1996 Smith GC, Clegg MS, Keen CL, Grivetti LE. Mineral values of selected plant foods common to southern Burkina Faso and to Niamey, Niger, West Africa International Journal of Food Sciences and Nutrition. 47: 41-53. PMID 8616672 DOI: 10.3109/09637489609028560  0.326
1996 Rucker RB, Romero-Chapman N, Wong T, Lee J, Steinberg FM, McGee C, Clegg MS, Reiser K, Kosonen T, Uriu-Hare JY, Murphy J, Keen CL. Modulation of lysyl oxidase by dietary copper in rats. The Journal of Nutrition. 126: 51-60. PMID 8558325 DOI: 10.1093/Jn/126.1.51  0.326
1996 Peters JM, Wiley LM, Zidenberg-Cherr S, Keen CL. Periconceptional zinc deficiency affects uterine 3H-estradiol binding in mice Teratogenesis Carcinogenesis and Mutagenesis. 15: 23-31. PMID 7604389 DOI: 10.1002/Tcm.1770150104  0.301
1995 Rogers JM, Taubeneck MW, Daston GP, Sulik KK, Zucker RM, Elstein KH, Jankowski MA, Keen CL. Zinc deficiency causes apoptosis but not cell cycle alterations in organogenesis-stage rat embryos: effect of varying duration of deficiency. Teratology. 52: 149-59. PMID 8638255 DOI: 10.1002/Tera.1420520307  0.342
1995 Olin KL, Golub MS, Gershwin ME, Hendrickx AG, Lonnerdal B, Keen CL. Extracellular superoxide dismutase activity is affected by dietary zinc intake in nonhuman primate and rodent models. The American Journal of Clinical Nutrition. 61: 1263-7. PMID 7762528 DOI: 10.1093/Ajcn/61.6.1263  0.385
1995 Liao Z, Allred J, Keen CL, McCune SA, Rucker RB, Medeiros DM. Copper deficiency alters isomyosin types and levels of laminin, fibronectin and cytochrome c oxidase subunits from rat hearts. Comparative Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology. 111: 61-7. PMID 7749637 DOI: 10.1016/0305-0491(94)00226-K  0.318
1995 Oteiza PI, Olin KL, Fraga CG, Keen CL. Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes. The Journal of Nutrition. 125: 823-9. PMID 7722683 DOI: 10.1093/Jn/125.4.823  0.376
1995 Olin KL, Morse LS, Murphy C, Paul-Murphy J, Line S, Bellhorn RW, Hjelmeland LM, Keen CL. Trace element status and free radical defense in elderly rhesus macaques (Macaca mulatta) with macular drusen. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 208: 370-7. PMID 7700885 DOI: 10.3181/00379727-208-43864  0.32
1995 Jankowski MA, Uriu-Hare JY, Rucker RB, Rogers JM, Keen CL. Maternal zinc deficiency, but not copper deficiency or diabetes, results in increased embryonic cell death in the rat: implications for mechanisms underlying abnormal development. Teratology. 51: 85-93. PMID 7660326 DOI: 10.1002/Tera.1420510207  0.362
1995 Golub MS, Keen CL, Gershwin ME, Hendrickx AG. Developmental zinc deficiency and behavior. The Journal of Nutrition. 125: 2263S-2271S. PMID 7623165 DOI: 10.1093/Jn/125.Suppl_8.2263S  0.329
1995 Clegg MS, Keen CL, Donovan SM. Zinc deficiency-induced anorexia influences the distribution of serum insulin-like growth factor-binding proteins in the rat Metabolism. 44: 1495-1501. PMID 7476340 DOI: 10.1016/0026-0495(95)90152-3  0.308
1994 Keen CL, Zidenberg-Cherr S. Should vitamin-mineral supplements be recommended for all women with childbearing potential? American Journal of Clinical Nutrition. 59. PMID 8304292 DOI: 10.1093/Ajcn/59.2.532S  0.361
1994 Taubeneck MW, Daston GP, Rogers JM, Keen CL. Altered maternal zinc metabolism following exposure to diverse developmental toxicants Reproductive Toxicology. 8: 25-40. PMID 8186621 DOI: 10.1016/0890-6238(94)90064-7  0.322
1994 Daston GP, Overmann GJ, Baines D, Taubeneck MW, Lehman-McKeeman LD, Rogers JM, Keen CL. Altered Zn status by alpha-hederin in the pregnant rat and its relationship to adverse developmental outcome. Reproductive Toxicology (Elmsford, N.Y.). 8: 15-24. PMID 8186620 DOI: 10.1016/0890-6238(94)90063-9  0.315
1994 Olin KL, Walter RM, Keen CL. Copper deficiency affects selenoglutathione peroxidase and selenodeiodinase activities and antioxidant defense in weanling rats American Journal of Clinical Nutrition. 59: 654-658. PMID 8116544 DOI: 10.1093/Ajcn/59.3.654  0.375
1994 Golub MS, Takeuchi PT, Keen CL, Gershwin ME, Hendrickx AG, Lonnerdal B. Modulation of behavioral performance of prepubertal monkeys by moderate dietary zinc deprivation. The American Journal of Clinical Nutrition. 60: 238-43. PMID 8030602 DOI: 10.1093/Ajcn/60.2.238  0.346
1994 Golub MS, Han B, Keen CL, Gershwin ME. Auditory startle in Swiss Webster mice fed excess aluminum in diet. Neurotoxicology and Teratology. 16: 423-5. PMID 7968944 DOI: 10.1016/0892-0362(94)90031-0  0.31
1994 Oster MH, Uriu-Hare JY, Trapp CL, Stern JS, Keen CL. Dietary macronutrient composition influences tissue trace element accumulation in diabetic Sprague-Dawley rats. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 207: 67-75. PMID 7938039 DOI: 10.3181/00379727-207-43793  0.319
1994 Domingo JL, Gomez M, Sanchez DJ, Llobet JM, Keen CL. Relationship between reduction in food intake and amelioration of hyperglycemia by oral vanadate in STZ-induced diabetic rats. Diabetes. 43: 1267, 1269-70. PMID 7926298 DOI: 10.2337/Diab.43.10.1267  0.306
1994 Bui LM, Keen CL, Dubick MA. Influence of 12-week nicotine treatment and dietary copper on blood pressure and indices of the antioxidant system in male spontaneous hypertensive rats Biological Trace Element Research. 46: 67-78. PMID 7888285 DOI: 10.1007/Bf02790068  0.304
1994 Graham TW, Thurmond MC, Gershwin ME, Picanso JP, Garvey JS, Keen CL. Serum zinc and copper concentrations in relation to spontaneous abortion in cows: Implications for human fetal loss Journal of Reproduction and Fertility. 102: 253-262. PMID 7799321 DOI: 10.1530/Jrf.0.1020253  0.33
1994 Vruwink KG, Gershwin ME, Keen CL. Effects of Gestational Zinc Deficiency in Mice on Growth and Immune Function Journal of Nutritional Immunology. 2: 25-41. DOI: 10.1300/J053V02N02_04  0.349
1994 Tamura T, Freeberg LE, Johnston KE, Keen CL. In vitro zinc stimulation of angiotensin-converting enzyme activities in various tissues of zinc-deficient rats Nutrition Research. 14: 919-928. DOI: 10.1016/S0271-5317(05)80492-0  0.334
1993 Arce DS, Keen CL. Effects of marginal and severe iron deficiency on hepatic proteins in developing rats are reversible with dietary iron repletion Reproductive Toxicology. 7: 61-72. PMID 8448418 DOI: 10.1016/0890-6238(93)90011-U  0.319
1993 Berger A, German JB, Chiang BL, Ansari AA, Keen CL, Fletcher MP, Gershwin ME. Influence of feeding unsaturated fats on growth and immune status of mice. The Journal of Nutrition. 123: 225-33. PMID 8381477 DOI: 10.1093/Jn/123.2.225  0.315
1993 Golub MS, Han B, Keen CL, Gershwin ME. Developmental patterns of aluminum in mouse brain and effects of dietary aluminum excess on manganese deficiency. Toxicology. 81: 33-47. PMID 8367880 DOI: 10.1016/0300-483X(93)90154-K  0.303
1993 Critchfield JW, Carl FG, Keen CL. Anticonvulsant-induced changes in tissue manganese, zinc, copper, and iron concentrations in Wistar rats. Metabolism: Clinical and Experimental. 42: 907-10. PMID 8345801 DOI: 10.1016/0026-0495(93)90068-Y  0.342
1993 Oster MH, Llobet JM, Domingo JL, German JB, Keen CL. Vanadium treatment of diabetic Sprague-Dawley rats results in tissue vanadium accumulation and pro-oxidant effects. Toxicology. 83: 115-30. PMID 8248940 DOI: 10.1016/0300-483X(93)90096-B  0.333
1993 Jankowski MA, Uriu-Hare JY, Rucker RB, Keen CL. Effect of maternal diabetes and dietary copper on fetal development in rats. Reproductive Toxicology (Elmsford, N.Y.). 7: 589-98. PMID 8118109 DOI: 10.1016/0890-6238(93)90035-6  0.35
1993 Peters JM, Wiley LM, Zidenberg-Cherr S, Keen CL. Influence of periconceptual zinc deficiency on embryonic plasma membrane function in mice Teratogenesis Carcinogenesis and Mutagenesis. 13: 15-21. PMID 8100649 DOI: 10.1002/Tcm.1770130103  0.304
1993 Humphry CM, Clegg MS, Keen CL, Grivetti LE. Food diversity and drought survival. The hausa example International Journal of Food Sciences and Nutrition. 44: 1-16. DOI: 10.3109/09637489309017417  0.308
1992 Golub MS, Han B, Keen CL, Gershwin ME. Effects of dietary aluminum excess and manganese deficiency on neurobehavioral endpoints in adult mice. Toxicology and Applied Pharmacology. 112: 154-60. PMID 1733044 DOI: 10.1016/0041-008X(92)90291-Y  0.308
1992 Keen CL. Maternal factors affecting teratogenic response: A need for assessment Teratology. 46: 15-21. PMID 1641806 DOI: 10.1002/Tera.1420460104  0.353
1992 Golub MS, Keen CL, Gershwin ME. Neurodevelopmental effect of aluminum in mice: fostering studies. Neurotoxicology and Teratology. 14: 177-82. PMID 1635538 DOI: 10.1016/0892-0362(92)90013-Z  0.313
1992 Arce DS, Keen CL. Reversible and persistent consequences of copper deficiency in developing mice Reproductive Toxicology. 6: 211-221. PMID 1591478 DOI: 10.1016/0890-6238(92)90176-T  0.309
1992 Golub MS, Tarantal AF, Gershwin ME, Keen CL, Hendrickx AG, Lonnerdal B. Ultrasound evaluation of fetuses of zinc-deprived monkeys (Macaca mulatta) American Journal of Clinical Nutrition. 55: 734-740. PMID 1550050 DOI: 10.1093/Ajcn/55.3.734  0.343
1992 Liu H, Oteiza PI, Gershwin ME, Golub MS, Keen CL. Effects of maternal marginal zinc deficiency on myelin protein profiles in the suckling rat and infant rhesus monkey. Biological Trace Element Research. 34: 55-66. PMID 1382522 DOI: 10.1007/Bf02783898  0.335
1992 Taubeneck MW, Domingo JL, Llobet JM, Keen CL. Meso-2,3-dimercaptosuccinic acid (DMSA) affects maternal and fetal copper metabolism in Swiss mice Toxicology. 72: 27-40. PMID 1311466 DOI: 10.1016/0300-483X(92)90083-Q  0.333
1991 Zidenberg-Cherr S, Olin KL, Villanueva J, Tang A, Phinney SD, Halsted CH, Keen CL. Ethanol-induced changes in hepatic free radical defense mechanisms and fatty-acid composition in the miniature pig Hepatology. 13: 1185-1192. PMID 2050333 DOI: 10.1002/Hep.1840130627  0.301
1991 Garrow TA, Clegg MS, Metzler G, Keen CL. Influence of hypertension and dietary copper on indexes of copper status in rats Hypertension. 17: 793-797. PMID 2045141 DOI: 10.1161/01.Hyp.17.6.793  0.381
1991 Reis BL, Keen CL, Lönnerdal B, Hurley LS. Mineral status of mice suckling early-, mid- and late-lactating foster dams. The Journal of Nutrition. 121: 700-10. PMID 2019879 DOI: 10.1093/Jn/121.5.700  0.335
1991 Daston GP, Overmann GJ, Taubeneck MW, Lehman-McKeeman LD, Rogers JM, Keen CL. The role of metallothionein induction and altered zinc status in maternally mediated developmental toxicity: comparison of the effects of urethane and styrene in rats. Toxicology and Applied Pharmacology. 110: 450-63. PMID 1949013 DOI: 10.1016/0041-008X(91)90046-H  0.367
1991 Peters JM, Wiley LM, Zidenberg-Cherr S, Keen CL. Influence of Short-Term Maternal Zinc Deficiency on the In Vitro Development of Preimplantation Mouse Embryos Proceedings of the Society For Experimental Biology and Medicine. 198: 561-568. PMID 1891470 DOI: 10.3181/00379727-198-43289  0.312
1991 Rosenbaum JS, Zidenberg-Cherr S, Keen CL. Influence of copper status on the response to acute ethanol exposure in rats Alcohol. 8: 473-479. PMID 1781925 DOI: 10.1016/S0741-8329(91)90170-2  0.315
1991 Golub MS, Keen CL, Hendrickx AG, Gershwin ME. Food preference of young rhesus monkeys fed marginally zinc deficient diets Primates. 32: 49-59. DOI: 10.1007/Bf02381600  0.346
1991 Graham TW, Feldman BF, Farver TB, Labavitch F, O'Nei11 SL, Thurmond MC, Keen CL, Holmberg CA. Zinc toxicosis of holstein veal calves and its relationship to haematological change and an associated thrombotic state Comparative Haematology International. 1: 121-128. DOI: 10.1007/Bf00515658  0.358
1990 Lönnerdal B, Keen CL, Bell JG, Golub MS, Hendrickx AG, Gershwin ME. Effect of marginal maternal zinc intake on zinc absorption and growth of 3-month-old infant rhesus monkeys. American Journal of Diseases of Children (1960). 144: 1007-10. PMID 2396612 DOI: 10.1001/Archpedi.1990.02150330067023  0.334
1990 Lowney P, Stern JS, Gershwin ME, Keen CL. Magnesium deficiency and blood 2,3-diphosphoglycerate concentrations in sedentary and exercised male Osborne-Mendel rats. Metabolism: Clinical and Experimental. 39: 837-41. PMID 2377080 DOI: 10.1016/0026-0495(90)90129-Z  0.32
1990 Fraga CG, Oteiza PI, Golub MS, Gershwin ME, Keen CL. Effects of aluminum on brain lipid peroxidation. Toxicology Letters. 51: 213-9. PMID 2330606 DOI: 10.1016/0378-4274(90)90212-5  0.302
1990 Turnlund JR, Keen CL, Smith RG. Copper status and urinary and salivary copper in young men at three levels of dietary copper. The American Journal of Clinical Nutrition. 51: 658-64. PMID 2321573 DOI: 10.1093/Ajcn/51.4.658  0.304
1990 Oteiza PI, Cuellar S, Lönnerdal B, Hurley LS, Keen CL. Influence of maternal dietary zinc intake on in vitro tubulin polymerization in fetal rat brain. Teratology. 41: 97-104. PMID 2305377 DOI: 10.1002/Tera.1420410110  0.308
1990 Oteiza PI, Hurley LS, Lönnerdal B, Keen CL. Effects of marginal zinc deficiency on microtubule polymerization in the developing rat brain. Biological Trace Element Research. 24: 13-23. PMID 1702656 DOI: 10.1007/Bf02789137  0.344
1990 Golub MS, Gershwin ME, Lonnerdal B, Keen CL, Hurley LS, Hendrickx AG. Problems associated with long-term feeding of purified diets in rhesus monkeys Primates. 31: 579-588. DOI: 10.1007/Bf02382541  0.347
1989 Donald JM, Golub MS, Gershwin ME, Keen CL. Neurobehavioral effects in offspring of mice given excess aluminum in diet during gestation and lactation. Neurotoxicology and Teratology. 11: 345-51. PMID 2796889 DOI: 10.1016/0892-0362(89)90005-6  0.328
1989 Uriu-Hare JY, Stern JS, Keen CL. Influence of maternal dietary Zn intake on expression of diabetes-induced teratogenicity in rats. Diabetes. 38: 1282-90. PMID 2792578 DOI: 10.2337/Diab.38.10.1282  0.333
1989 Golub MS, Donald JM, Gershwin ME, Keen CL. Effects of aluminum ingestion on spontaneous motor activity of mice. Neurotoxicology and Teratology. 11: 231-5. PMID 2755419 DOI: 10.1016/0892-0362(89)90064-0  0.335
1989 Amemiya K, Hurley LS, Keen CL. Effect of 6-mercaptopurine on 65Zn distribution in the pregnant rat. Teratology. 39: 387-93. PMID 2749581 DOI: 10.1002/Tera.1420390410  0.303
1989 Keen CL, Peters JM, Hurley LS. The effect of valproic acid on 65Zn distribution in the pregnant rat. The Journal of Nutrition. 119: 607-11. PMID 2495343 DOI: 10.1093/Jn/119.4.607  0.302
1988 Chung K, Romero N, Tinker D, Keen CL, Amemiya K, Rucker R. Role of copper in the regulation and accumulation of superoxide dismutase and metallothionein in rat liver. The Journal of Nutrition. 118: 859-64. PMID 3392595 DOI: 10.1093/Jn/118.7.859  0.313
1988 Keen CL, Golub MS, Gershwin ME, Lönnerdal B, Hurley LS. Studies of marginal zinc deprivation in rhesus monkeys. III. Use of liver biopsy in the assessment of zinc status. The American Journal of Clinical Nutrition. 47: 1041-5. PMID 3376902 DOI: 10.1093/Ajcn/47.6.1041  0.321
1988 Peters JM, Lönnerdal B, Keen CL. Effect of the antihypertensive drug hydralazine on mineral metabolism in the rat Toxicology Letters. 41: 193-202. PMID 3376146 DOI: 10.1016/0378-4274(88)90054-9  0.301
1988 Oteiza PI, Hurley LS, Lonnerdal B, Keen CL. Marginal zinc deficiency affects maternal brain microtubule assembly in rats Journal of Nutrition. 118: 735-738. PMID 3373339 DOI: 10.1093/Jn/118.6.735  0.316
1988 Morgan PN, Keen CL, Lonnerdal B. Effect of varying dietary zinc intake of weanling mouse pups during recovery from early undernutrition on tissue mineral concentrations, relative organ weights, hematological variables and muscle composition Journal of Nutrition. 118: 699-711. PMID 3373334 DOI: 10.1093/Jn/118.6.699  0.354
1988 Morgan PN, Keen CL, Calvert CC, Lonnerdal B. Effect of varying dietary zinc intake of weanling mouse pups during recovery from early undernutrition on growth, body composition and composition of gain Journal of Nutrition. 118: 690-698. PMID 3373333 DOI: 10.1093/Jn/118.6.690  0.364
1988 McDonald R, Keen CL. Iron, Zinc and Magnesium Nutrition and Athletic Performance Sports Medicine. 5: 171-184. PMID 3285436 DOI: 10.2165/00007256-198805030-00004  0.337
1988 Graham TW, Holmberg CA, Keen CL, Thurmond MC, Clegg MS. A Pathologic and Toxicologic Evaluation of Veal Calves Fed Large Amounts of Zinc Veterinary Pathology. 25: 484-491. PMID 3212892 DOI: 10.1177/030098588802500612  0.305
1988 Lönnerdal B, Bell JG, Hendrickx AG, Burns RA, Keen CL. Effect of phytate removal on zinc absorption from soy formula. The American Journal of Clinical Nutrition. 48: 1301-6. PMID 3189220 DOI: 10.1093/Ajcn/48.5.1301  0.3
1988 Lowney P, Gershwin ME, Hurley LS, Stern JS, Keen CL. The effect of variable magnesium intake on potential factors influencing endurance capacity. Biological Trace Element Research. 16: 1-18. PMID 2484531 DOI: 10.1007/Bf02795329  0.36
1987 Vruwink KG, Keen CL, Gershwin ME, Hurley LS. Studies of nutrition and autoimmunity. Failure of zinc deprivation to alter autoantibody production when initiated in disease-established mice Journal of Nutrition. 117: 177-182. PMID 3819865 DOI: 10.1093/Jn/117.1.177  0.351
1987 Rogers JM, Lonnerdal B, Hurley LS, Keen CL. Iron and zinc concentrations and 59Fe retention in developing fetuses of zinc-deficient rats Journal of Nutrition. 117: 1875-1882. PMID 3681478 DOI: 10.1093/Jn/117.11.1875  0.343
1987 Bell JG, Keen CL, Lönnerdal B. Effect of Infant Cereals on Zinc and Copper Absorption During Weaning American Journal of Diseases of Children. 141: 1128-1132. PMID 3631002 DOI: 10.1001/Archpedi.1987.04460100106041  0.342
1987 Keen CL, Lowney P, Gershwin ME, Hurley LS, Stern JS. Dietary magnesium intake influences exercise capacity and hematologic parameters in rats. Metabolism: Clinical and Experimental. 36: 788-93. PMID 3600291 DOI: 10.1016/0026-0495(87)90118-1  0.31
1987 Reinstein NH, Lönnerdal B, Keen CL, Schneeman BO, Hurley LS. The effect of varying dietary zinc levels on the concentration and localization of zinc in rat bile-pancreatic fluid. The Journal of Nutrition. 117: 1060-6. PMID 3598716 DOI: 10.1093/Jn/117.6.1060  0.32
1987 Kawano J, Ney DM, Keen CL, Schneeman BO. Altered high density lipoprotein composition in manganese-deficient Sprague-Dawley and Wistar rats. The Journal of Nutrition. 117: 902-6. PMID 3585544 DOI: 10.1093/Jn/117.5.902  0.332
1987 Clegg MS, Ferrell F, Keen CL. Hypertension-induced alterations in copper and zinc metabolism in Dahl rats Hypertension. 9: 624-628. PMID 3583402 DOI: 10.1161/01.Hyp.9.6.624  0.373
1987 Elfant M, Keen CL. Sodium vanadate toxicity in adult and developing rats - Role of peroxidative damage Biological Trace Element Research. 14: 193-208. DOI: 10.1007/Bf02795686  0.365
1986 Keen CL, Bell JG, Lonnerdal B. The effect of age on manganese uptake and retention from milk and infant formulas in rats Journal of Nutrition. 116: 395-402. PMID 3950766 DOI: 10.1093/Jn/116.3.395  0.33
1986 Mieden GD, Keen CL, Hurley LS, Klein NW. Effects of whole rat embryos cultured on serum from zinc- and copper-deficient rats Journal of Nutrition. 116: 2424-2431. PMID 3806239 DOI: 10.1093/Jn/116.12.2424  0.335
1986 Amemiya K, Keen CL, Hurley LS. 6-Mercaptopurine-induced alterations in mineral metabolism and teratogenesis in the rat Teratology. 34: 321-334. PMID 3798368 DOI: 10.1002/Tera.1420340312  0.352
1986 Masters DG, Keen CL, Lonnerdal B, Hurley LS. Release of zinc from maternal tissues during zinc deficiency or simultaneous zinc and calcium deficiency in the pregnant rat Journal of Nutrition. 116: 2148-2154. PMID 3794823 DOI: 10.1093/Jn/116.11.2148  0.328
1986 Schneeman BO, Lacy D, Ney D, Lefevre ML, Keen CL, Lönnerdal B, Hurley LS. Similar effects of zinc deficiency and restricted feeding on plasma lipids and lipoproteins in rats. The Journal of Nutrition. 116: 1889-95. PMID 3772519 DOI: 10.1093/Jn/116.10.1889  0.393
1986 Peters AJ, Keen CL, Lönnerdal B, Hurley LS. Zinc-vitamin A interaction in pregnant and fetal rats: supplemental vitamin A does not prevent zinc-deficiency-induced teratogenesis. The Journal of Nutrition. 116: 1765-71. PMID 3761031 DOI: 10.1093/Jn/116.9.1765  0.385
1986 Munoz L, Keen CL, Lonnerdal B, Dewey KG. Coffee intake during pregnancy and lactation in rats: Maternal and pup hematological parameters and liver iron, zinc and copper concentration Journal of Nutrition. 116: 1326-1333. PMID 3746467 DOI: 10.1093/Jn/116.7.1326  0.341
1986 Kawamoto JC, Castonguay TW, Keen CL, Stern JS, Hurley LS. Age, sex and reproductive status alter the severity of anorexia in zinc deficient rats. Physiology & Behavior. 38: 485-93. PMID 3469681 DOI: 10.1016/0031-9384(86)90415-4  0.371
1986 Clegg MS, Lönnerdal B, Hurley LS, Keen CL. Analysis of whole blood manganese by flameless atomic absorption spectrophotometry and its use as an indicator of manganese status in animals Analytical Biochemistry. 157: 12-18. PMID 3021019 DOI: 10.1016/0003-2697(86)90189-2  0.313
1986 Lefevre M, Keen CL, Lönnerdal B, Hurley LS, Schneeman BO. Copper deficiency-induced hypercholesterolemia: effects on HDL subfractions and hepatic lipoprotein receptor activity in the rat. The Journal of Nutrition. 116: 1735-46. PMID 3020202 DOI: 10.1093/Jn/116.9.1735  0.303
1986 Baly DL, Keen CL, Hurley LS. Effects of manganese deficiency on pyruvate carboxylase and phosphoenolpyruvate carboxykinase activity and carbohydrate homeostasis in adult rats Biological Trace Element Research. 11: 201-212. DOI: 10.1007/Bf02795535  0.301
1986 Amemiya K, Hurley LS, Keen CL. Effect of 6-mercaptopurine on mineral and metallothionein metabolism in the mouse Biological Trace Element Research. 11: 161-175. DOI: 10.1007/Bf02795532  0.303
1985 Lonnerdal B, Bell JG, Keen CL. Copper absorption from human milk, cow's milk, and infant formulas using a suckling rat model American Journal of Clinical Nutrition. 42: 836-844. PMID 4061345 DOI: 10.1093/Ajcn/42.5.836  0.33
1985 Dubick MA, Keen CL. Alterations in tissue trace element and ascorbic acid metabolism in phenytoin-fed rats and mice Journal of Nutrition. 115: 1481-1487. PMID 4056943 DOI: 10.1093/Jn/115.11.1481  0.334
1985 Baly DL, Keen CL, Hurley LS. Pyruvate carboxylase and phosphoenolpyruvate carboxykinase activity in developing rats: Effect of manganese deficiency Journal of Nutrition. 115: 872-879. PMID 4009297 DOI: 10.1093/Jn/115.7.872  0.305
1985 Cohen NL, Keen CL, Hurley LS, Lonnerdal B. Determinants of copper-deficiency anemia in rats Journal of Nutrition. 115: 710-725. PMID 3998865 DOI: 10.1093/Jn/115.6.710  0.323
1985 Rogers JM, Keen CL, Hurley LS. Zinc deficiency in pregnant long-evans hooded rats: Teratogenicity and tissue trace elements Teratology. 31: 89-100. PMID 3983863 DOI: 10.1002/Tera.1420310111  0.32
1985 Zidenberg-Cherr S, Hurley LS, Lonnerdal B, Keen CL. Manganese deficiency: Effects on susceptibility to ethanol toxicity in rats Journal of Nutrition. 115: 460-467. PMID 3981264 DOI: 10.1093/Jn/115.4.460  0.304
1985 Lefevre M, Keen CL, Lönnerdal B, Hurley LS, Schneeman BO. Different effects of zinc and copper deficiency on composition of plasma high density lipoproteins in rats. The Journal of Nutrition. 115: 359-68. PMID 3973747 DOI: 10.1093/Jn/115.3.359  0.336
1985 Lonnerdal B, Keen CL, Hurley LS. Manganese binding proteins in human and cow's milk American Journal of Clinical Nutrition. 41: 550-559. PMID 3872058 DOI: 10.1093/Ajcn/41.3.550  0.313
1985 Cohen NL, Keen CL, Lonnerdal B, Hurley LS. Effects of varying dietary iron on the expression of copper deficiency in the growing rat: Anemia, ferroxidase I and II, tissue trace elements, ascorbic acid, and xanthine dehydrogenase Journal of Nutrition. 115: 633-649. PMID 3858456 DOI: 10.1093/Jn/115.5.633  0.321
1985 Dubick MA, Keen CL, Rucker RB. Elastin metabolism during perinatal lung development in the copper-deficient rat. Experimental Lung Research. 8: 227-41. PMID 2864245 DOI: 10.3109/01902148509087806  0.328
1984 Kwock RO, Keen CL, Hegenauer J, Saltman P, Hurley LS, Lönnerdal B. Retention and distribution of iron added to cow's milk and human milk as various salts and chelates. The Journal of Nutrition. 114: 1454-61. PMID 6747728 DOI: 10.1093/Jn/114.8.1454  0.317
1984 Reinstein NH, Lonnerdahl B, Keen CL, Hurley LS. Zinc-copper interactions in the pregnant rat: Fetal outcome and maternal and fetal zinc, copper and iron Journal of Nutrition. 114: 1266-1279. PMID 6737088 DOI: 10.1093/Jn/114.7.1266  0.377
1984 Keen CL, Fransson GB, Lönnerdal B. Supplementation of milk with iron bound to lactoferrin using weanling mice. II: Effects on tissue manganese, zinc, and copper Journal of Pediatric Gastroenterology and Nutrition. 3: 256-261. PMID 6707846 DOI: 10.1097/00005176-198403000-00016  0.333
1984 Keen CL, Cohen NL, Hurley LS, Lönnerdal B. Molecular localization of copper and zinc in rat fetal liver in dietary and drug-induced copper deficiency Biochemical and Biophysical Research Communications. 118: 697-703. PMID 6704101 DOI: 10.1016/0006-291X(84)91450-5  0.325
1984 Zidenberg-Cherr S, Keen CL, Lönnerdal B, Hurley LS. Superoxide dismutase activity and lipid peroxidation in the rat: developmental correlations affected by manganese deficiency. The Journal of Nutrition. 113: 2498-504. PMID 6655513 DOI: 10.1093/Jn/113.12.2498  0.309
1984 Lönnerdal B, Keen CL, Glazier CE, Anderson J. A Longitudinal Study of Rhesus Monkey ( Macaca mulatta ) Milk Composition: Trace Elements, Minerals, Protein, Carbohydrate, and Fat Pediatric Research. 18: 911-914. PMID 6483513 DOI: 10.1203/00006450-198409000-00023  0.308
1983 Hurley LS, Dungan DD, Keen CL, Lonnerdal B. The effects of vitamin E on zinc deficiency teratogenesis in rats Journal of Nutrition. 113: 1875-1877. PMID 6886830 DOI: 10.1093/Jn/113.9.1875  0.356
1983 Masters DG, Keen CL, Lönnerdal B, Hurley LS. Comparative aspects of dietary copper and zinc deficiencies in pregnant rats Journal of Nutrition. 113: 1448-1451. PMID 6864343 DOI: 10.1093/Jn/113.7.1448  0.362
1983 Cohen NL, Keen CL, Lönnerdal B, Hurley LS. The effect of copper chelating drugs on liver iron mobilization in the adult rat Biochemical and Biophysical Research Communications. 113: 127-134. PMID 6860330 DOI: 10.1016/0006-291X(83)90441-2  0.326
1983 Zidenberg-Cherr S, Keen CL, Lönnerdal B, Hurley LS. Dietary superoxide dismutase does not affect tissue levels. The American Journal of Clinical Nutrition. 37: 5-7. PMID 6849282 DOI: 10.1093/Ajcn/37.1.5  0.354
1983 Masters DG, Keen CL, Lonnerdal B, Hurley LS. Zinc deficiency teratogenicity: The protective role of maternal tissue catabolism Journal of Nutrition. 113: 905-912. PMID 6834156 DOI: 10.1093/Jn/113.4.905  0.383
1983 Mark-Savage P, Keen CL, Hurley LS. Reduction by copper supplementation of teratogenic effects of D-penicillamine. The Journal of Nutrition. 113: 501-10. PMID 6827370 DOI: 10.1093/Jn/113.3.501  0.358
1983 Sandstrom B, Keen CL, Lonnerdal B. An experimental model for studies of zinc bioavailability from milk and infant formulas using extrinsic labeling American Journal of Clinical Nutrition. 38: 420-428. PMID 6684392 DOI: 10.1093/Ajcn/38.3.420  0.361
1983 Keen CL, Cohen NL, Lönnerdal b, Hurley LS. Teratogenesis and Low Copper Status Resulting from Triethylenetetramine in Rats Proceedings of the Society For Experimental Biology and Medicine. 173: 598-605. PMID 6684289 DOI: 10.3181/00379727-173-41693  0.323
1983 Doong G, Keen CL, Rogers Q, Morris J, Rucker RB. Selected features of copper metabolism in the cat. The Journal of Nutrition. 113: 1963-71. PMID 6619976 DOI: 10.1093/Jn/113.10.1963  0.348
1982 Keen CL, Mark-Savage P, Lönnerdal B, Hurley LS. Teratogenesis and low copper status resulting from D-penicillamine in rats. Teratology. 26: 163-5. PMID 7157192 DOI: 10.1002/Tera.1420260208  0.303
1982 Keen CL, Feldman BF, Knight J, O'Neill S, Ferrell F, Hurley LS. The influence of high concentrations of dietary copper on vitamin K-dependent coagulation factors. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 170: 471-5. PMID 7122476 DOI: 10.3181/00379727-170-41461  0.363
1982 Hurley LS, Gordon P, Keen CL, Merkhofer L. Circadian Variation in Rat Plasma Zinc and Rapid Effect of Dietary Zinc Deficiency Proceedings of the Society For Experimental Biology and Medicine. 170: 48-52. PMID 7079271 DOI: 10.3181/00379727-170-41395  0.35
1982 Keen CL, Lönnerdal B, Hurley LS. Increased milk iron by dietary supplementation-entirely beneficial? American Journal of Clinical Nutrition. 35: 627-628. PMID 7064913 DOI: 10.1093/Ajcn/35.3.627A  0.328
1982 Keen CL, Lonnerdal B, Clegg MS, Hurley LS, Morris JG, Rogers QR, Rucker RB. Developmental changes in composition of cats milk: trace elements, minerals, protein, carbohydrate and fat. The Journal of Nutrition. 112: 1763-9. PMID 6213745 DOI: 10.1093/Jn/112.9.1763  0.314
1980 Keen CL, Lönnerdal B, Sloan MV, Hurley LS. Effects of milking procedure on rat milk composition Physiology and Behavior. 24: 613-615. PMID 7375582 DOI: 10.1016/0031-9384(80)90259-0  0.301
1980 Keen CL, Lonnerdal B, Sloan MV, Hurley LS. Effect of dietary iron, copper and zinc chelates of nitrilotriacetic acid (NTA) on trace metal concentrations in rat milk and maternal and pup tissues Journal of Nutrition. 110: 897-906. PMID 7373436 DOI: 10.1093/Jn/110.5.897  0.355
1980 De Rosa G, Keen CL, Leach RM, Hurley LS. Regulation of superoxide dismutase activity by dietary manganese Journal of Nutrition. 110: 795-804. PMID 7365547 DOI: 10.1093/Jn/110.4.795  0.356
1980 Keen CL, Lönnerdal B, Stein TN, Hurley LS. Superoxide dismutase isoenzymes in bovine and human milk Biological Trace Element Research. 2: 221-227. DOI: 10.1007/Bf02785357  0.302
1980 LöNNERDAL B, Keen CL, Hoffman B, Hurley LS. Copper Ligands in Human Milk: A Vehicle for Copper Supplementation in the Treatment of Menkes’ Disease? American Journal of Diseases of Children. 134: 802-803. DOI: 10.1001/Archpedi.1980.02130200070029  0.306
1979 Keen CL, Hurley LS. Superoxide Dismutase Activity in the Crinkled Mutant Mouse: Ameliorative Effects of Dietary Copper Supplementation Proceedings of the Society For Experimental Biology and Medicine. 162: 152-156. PMID 504225 DOI: 10.3181/00379727-162-40636  0.337
1977 Keen CL, Hurley LS. Zinc absorption through skin: correction of zinc deficiency in the rat American Journal of Clinical Nutrition. 30: 528-530. PMID 851081 DOI: 10.1093/Ajcn/30.4.528  0.374
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