Thomas Haynes Hutson - Publications

Affiliations: 
Wolfson Centre for Age-Related Diseases King's College (London), London, England, United Kingdom 

30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 De Virgiliis F, Mueller F, Palmisano I, Chadwick JS, Luengo-Gutierrez L, Giarrizzo A, Yan Y, Danzi MC, Picon-Muñoz C, Zhou L, Kong G, Serger E, Hutson TH, Maldonado-Lasuncion I, Song Y, et al. The circadian clock time tunes axonal regeneration. Cell Metabolism. PMID 37951214 DOI: 10.1016/j.cmet.2023.10.012  0.329
2023 Squair JW, Milano M, de Coucy A, Gautier M, Skinnider MA, James ND, Cho N, Lasne A, Kathe C, Hutson TH, Ceto S, Baud L, Galan K, Aureli V, Laskaratos A, et al. Recovery of walking after paralysis by regenerating characterized neurons to their natural target region. Science (New York, N.Y.). 381: 1338-1345. PMID 37733871 DOI: 10.1126/science.adi6412  0.796
2022 Anderson MA, Squair JW, Gautier M, Hutson TH, Kathe C, Barraud Q, Bloch J, Courtine G. Natural and targeted circuit reorganization after spinal cord injury. Nature Neuroscience. 25: 1584-1596. PMID 36396975 DOI: 10.1038/s41593-022-01196-1  0.788
2022 Kathe C, Skinnider MA, Hutson TH, Regazzi N, Gautier M, Demesmaeker R, Komi S, Ceto S, James ND, Cho N, Baud L, Galan K, Matson KJE, Rowald A, Kim K, et al. The neurons that restore walking after paralysis. Nature. 611: 540-547. PMID 36352232 DOI: 10.1038/s41586-022-05385-7  0.808
2021 Squair JW, Gautier M, Kathe C, Anderson MA, James ND, Hutson TH, Hudelle R, Qaiser T, Matson KJE, Barraud Q, Levine AJ, La Manno G, Skinnider MA, Courtine G. Confronting false discoveries in single-cell differential expression. Nature Communications. 12: 5692. PMID 34584091 DOI: 10.1038/s41467-021-25960-2  0.744
2021 Kathe C, Michoud F, Schönle P, Rowald A, Brun N, Ravier J, Furfaro I, Paggi V, Kim K, Soloukey S, Asboth L, Hutson TH, Jelescu I, Philippides A, Alwahab N, et al. Wireless closed-loop optogenetics across the entire dorsoventral spinal cord in mice. Nature Biotechnology. PMID 34580478 DOI: 10.1038/s41587-021-01019-x  0.791
2020 De Virgiliis F, Hutson TH, Palmisano I, Amachree S, Miao J, Zhou L, Todorova R, Thompson R, Danzi MC, Lemmon VP, Bixby JL, Wittig I, Shah AM, Di Giovanni S. Enriched conditioning expands the regenerative ability of sensory neurons after spinal cord injury via neuronal intrinsic redox signaling. Nature Communications. 11: 6425. PMID 33349630 DOI: 10.1038/s41467-020-20179-z  0.476
2020 Kong G, Zhou L, Serger E, Palmisano I, De Virgiliis F, Hutson TH, Mclachlan E, Freiwald A, La Montanara P, Shkura K, Puttagunta R, Di Giovanni S. AMPK controls the axonal regenerative ability of dorsal root ganglia sensory neurons after spinal cord injury. Nature Metabolism. PMID 32778834 DOI: 10.1038/s42255-020-0252-3  0.414
2020 Skinnider MA, Squair JW, Kathe C, Anderson MA, Gautier M, Matson KJE, Milano M, Hutson TH, Barraud Q, Phillips AA, Foster LJ, La Manno G, Levine AJ, Courtine G. Cell type prioritization in single-cell data. Nature Biotechnology. PMID 32690972 DOI: 10.1038/S41587-020-0605-1  0.744
2020 La Montanara P, Hervera A, Baltussen LL, Hutson TH, Palmisano I, De Virgiliis F, Kong G, Chadwick J, Gao Y, Bartus K, Majid QA, Gorgoraptis N, Wong K, Downs J, Pizzorusso T, et al. Cyclin-dependent-like kinase 5 is required for pain signaling in human sensory neurons and mouse models. Science Translational Medicine. 12. PMID 32641489 DOI: 10.1126/Scitranslmed.Aax4846  0.343
2019 Hutson TH, Di Giovanni S. The translational landscape in spinal cord injury: focus on neuroplasticity and regeneration. Nature Reviews. Neurology. 15: 732-745. PMID 31728042 DOI: 10.1038/S41582-019-0280-3  0.577
2019 Palmisano I, Danzi MC, Hutson TH, Zhou L, McLachlan E, Serger E, Shkura K, Srivastava PK, Hervera A, Neill NO, Liu T, Dhrif H, Wang Z, Kubat M, Wuchty S, et al. Epigenomic signatures underpin the axonal regenerative ability of dorsal root ganglia sensory neurons. Nature Neuroscience. PMID 31591560 DOI: 10.1038/S41593-019-0490-4  0.458
2019 Hervera A, Zhou L, Palmisano I, McLachlan E, Kong G, Hutson TH, Danzi MC, Lemmon VP, Bixby JL, Matamoros-Angles A, Forsberg K, De Virgiliis F, Matheos DP, Kwapis J, Wood MA, et al. PP4-dependent HDAC3 dephosphorylation discriminates between axonal regeneration and regenerative failure. The Embo Journal. 38: e101032. PMID 31268609 DOI: 10.15252/Embj.2018101032  0.535
2019 Hervera A, Zhou L, Palmisano I, McLachlan E, Kong G, Hutson TH, Danzi MC, Lemmon VP, Bixby JL, Matamoros-Angles A, Forsberg K, De Virgiliis F, Matheos DP, Kwapis J, Wood MA, et al. PP4-dependent HDAC3 dephosphorylation discriminates between axonal regeneration and regenerative failure. The Embo Journal. PMID 31118250 DOI: 10.15252/embj.2018101032  0.444
2019 Hutson TH, Kathe C, Palmisano I, Bartholdi K, Hervera A, De Virgiliis F, McLachlan E, Zhou L, Kong G, Barraud Q, Danzi MC, Medrano-Fernandez A, Lopez-Atalaya JP, Boutillier AL, Sinha SH, et al. Cbp-dependent histone acetylation mediates axon regeneration induced by environmental enrichment in rodent spinal cord injury models. Science Translational Medicine. 11. PMID 30971452 DOI: 10.1126/Scitranslmed.Aaw2064  0.822
2018 Hervera A, De Virgiliis F, Palmisano I, Zhou L, Tantardini E, Kong G, Hutson T, Danzi MC, Perry RB, Santos CXC, Kapustin AN, Fleck RA, Del Río JA, Carroll T, Lemmon V, et al. Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons. Nature Cell Biology. PMID 29434374 DOI: 10.1038/S41556-018-0039-X  0.395
2016 Kathe C, Hutson TH, McMahon SB, Moon LD. Intramuscular Neurotrophin-3 normalizes low threshold spinal reflexes, reduces spasms and improves mobility after bilateral corticospinal tract injury in rats. Elife. 5. PMID 27759565 DOI: 10.7554/Elife.18146  0.801
2016 Harrison BJ, Venkat G, Lamb JL, Hutson TH, Drury C, Rau KK, Bunge MB, Mendell LM, Gage FH, Johnson RD, Hill CE, Rouchka EC, Moon LD, Petruska JC. The Adaptor Protein CD2AP Is a Coordinator of Neurotrophin Signaling-Mediated Axon Arbor Plasticity. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 36: 4259-75. PMID 27076424 DOI: 10.1523/Jneurosci.2423-15.2016  0.755
2016 Haenzi B, Gers-Barlag K, Akhoundzadeh H, Hutson TH, Menezes SC, Bunge MB, Moon LD. Overexpression of the Fibroblast Growth Factor Receptor 1 (FGFR1) in a Model of Spinal Cord Injury in Rats. Plos One. 11: e0150541. PMID 27015635 DOI: 10.1371/Journal.Pone.0150541  0.801
2015 Harrison BJ, Venkat G, Hutson T, Rau KK, Bunge MB, Mendell LM, Gage FH, Johnson RD, Hill C, Rouchka EC, Moon L, Petruska JC. Transcriptional changes in sensory ganglia associated with primary afferent axon collateral sprouting in spared dermatome model. Genomics Data. 6: 249-52. PMID 26697387 DOI: 10.1016/J.Gdata.2015.10.005  0.795
2015 Hutson TH, Kathe C, Moon LD. Trans-neuronal transduction of spinal neurons following cortical injection and anterograde axonal transport of a bicistronic AAV1 vector. Gene Therapy. PMID 26656848 DOI: 10.1038/Gt.2015.103  0.807
2015 Duricki DA, Hutson TH, Kathe C, Soleman S, Gonzalez-Carter D, Petruska JC, Shine HD, Chen Q, Wood TC, Bernanos M, Cash D, Williams SC, Gage FH, Moon LD. Delayed intramuscular human neurotrophin-3 improves recovery in adult and elderly rats after stroke. Brain : a Journal of Neurology. PMID 26614754 DOI: 10.1093/Brain/Awv341  0.664
2014 Kathe C, Hutson TH, Chen Q, Shine HD, McMahon SB, Moon LD. Unilateral pyramidotomy of the corticospinal tract in rats for assessment of neuroplasticity-inducing therapies. Journal of Visualized Experiments : Jove. PMID 25549050 DOI: 10.3791/51843  0.776
2014 Hutson TH, Kathe C, Menezes SC, Rooney MC, Bueler H, Moon LD. The use of an adeno-associated viral vector for efficient bicistronic expression of two genes in the central nervous system. Methods in Molecular Biology (Clifton, N.J.). 1162: 189-207. PMID 24838969 DOI: 10.1007/978-1-4939-0777-9_16  0.792
2014 Hutson TH, Foster E, Moon LD, Yáñez-Muñoz RJ. Lentiviral vector-mediated RNA silencing in the central nervous system. Human Gene Therapy Methods. 25: 14-32. PMID 24090197 DOI: 10.1089/Hgtb.2013.016  0.661
2013 Peluffo H, Foster E, Ahmed SG, Lago N, Hutson TH, Moon L, Yip P, Wanisch K, Caraballo-Miralles V, Olmos G, Lladó J, McMahon SB, Yáñez-Muñoz RJ. Efficient gene expression from integration-deficient lentiviral vectors in the spinal cord. Gene Therapy. 20: 645-57. PMID 23076378 DOI: 10.1038/Gt.2012.78  0.787
2012 Buchser WJ, Smith RP, Pardinas JR, Haddox CL, Hutson T, Moon L, Hoffman SR, Bixby JL, Lemmon VP. Peripheral nervous system genes expressed in central neurons induce growth on inhibitory substrates. Plos One. 7: e38101. PMID 22701605 DOI: 10.1371/Journal.Pone.0038101  0.743
2012 Hutson TH, Foster E, Dawes JM, Hindges R, Yáñez-Muñoz RJ, Moon LD. Lentiviral vectors encoding short hairpin RNAs efficiently transduce and knockdown LINGO-1 but induce an interferon response and cytotoxicity in central nervous system neurones. The Journal of Gene Medicine. 14: 299-315. PMID 22499506 DOI: 10.1002/Jgm.2626  0.737
2012 Hutson TH, Verhaagen J, Yáñez-Muñoz RJ, Moon LD. Corticospinal tract transduction: a comparison of seven adeno-associated viral vector serotypes and a non-integrating lentiviral vector. Gene Therapy. 19: 49-60. PMID 21562590 DOI: 10.1038/Gt.2011.71  0.777
2011 Hutson TH, Buchser WJ, Bixby JL, Lemmon VP, Moon LD. Optimization of a 96-Well Electroporation Assay for Postnatal Rat CNS Neurons Suitable for Cost-Effective Medium-Throughput Screening of Genes that Promote Neurite Outgrowth. Frontiers in Molecular Neuroscience. 4: 55. PMID 22207835 DOI: 10.3389/Fnmol.2011.00055  0.721
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