Max Gassmann, MD/PhD - Publications

Affiliations: 
Institute of Veterinary Physiology Universität Zürich, Zürich, ZH, Switzerland 
Website:
http://www.vetphys.uzh.ch/missionstatement/staff/management.html

175 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Aboouf MA, Thiel CS, Borisov SM, Tauber S, Bönzli E, Schetle N, Ullrich O, Gassmann M, Vogel J. Expression of hypoxia-inducible genes is suppressed in altered gravity due to impaired nuclear HIF1α accumulation. Scientific Reports. 13: 14514. PMID 37666879 DOI: 10.1038/s41598-023-41686-1  0.584
2022 Baumann J, Tsao CC, Patkar S, Huang SF, Francia S, Magnussen SN, Gassmann M, Vogel J, Köster-Hegmann C, Ogunshola OO. Pericyte, but not astrocyte, hypoxia inducible factor-1 (HIF-1) drives hypoxia-induced vascular permeability in vivo. Fluids and Barriers of the Cns. 19: 6. PMID 35033138 DOI: 10.1186/s12987-021-00302-y  0.603
2021 Ademi H, Shinde DA, Gassmann M, Gerst D, Chaachouay H, Vogel J, Gorr TA. Targeting neovascularization and respiration of tumor grafts grown on chick embryo chorioallantoic membranes. Plos One. 16: e0251765. PMID 33999935 DOI: 10.1371/journal.pone.0251765  0.554
2020 Gassmann M, Cowburn A, Gu H, Li J, Rodriguez M, Babicheva A, Jain PP, Xiong M, Gassmann NN, Yuan JX, Wilkins MR, Zhao L. Hypoxia-induced pulmonary hypertension - utilising experiments of nature. British Journal of Pharmacology. PMID 32464698 DOI: 10.1111/Bph.15144  0.331
2020 Dey S, Cui Z, Gavrilova O, Zhang X, Gassmann M, Noguchi CT. Sex-specific brain erythropoietin regulation of mouse metabolism and hypothalamic inflammation. Jci Insight. PMID 32078583 DOI: 10.1172/Jci.Insight.134061  0.369
2019 Skaria T, Mitchell K, Vogel O, Wälchli T, Gassmann M, Vogel J. Blood Pressure Normalization-Independent Cardioprotective Effects of Endogenous, Physical Activity-Induced Alpha Calcitonin Gene-Related Peptide (αCGRP) in Chronically Hypertensive Mice. Circulation Research. PMID 31665965 DOI: 10.1161/Circresaha.119.315429  0.638
2019 Daryadel A, Natale L, Seebeck P, Bettoni C, Schnitzbauer U, Gassmann M, Wagner CA. Elevated FGF23 and disordered renal mineral handling with reduced bone mineralization in chronically erythropoietin over-expressing transgenic mice. Scientific Reports. 9: 14989. PMID 31628396 DOI: 10.1038/S41598-019-51577-Z  0.315
2019 Nageswara Rao T, Hansen N, Hilfiker J, Rai S, Majewska JM, Leković D, Gezer D, Andina N, Galli S, Cassel T, Geier F, Delezie J, Nienhold R, Hao-Shen H, Beisel C, ... ... Gassmann M, et al. JAK2 mutant hematopoietic cells display metabolic alterations that can be targeted to treat myeloproliferative neoplasms. Blood. PMID 31511238 DOI: 10.1182/Blood.2019000162  0.31
2019 Baumann J, Huang SF, Gassmann M, Tsao CC, Ogunshola OO. Furin inhibition prevents hypoxic and TGFβ-mediated blood-brain barrier disruption. Experimental Cell Research. 111503. PMID 31336100 DOI: 10.1016/J.Yexcr.2019.111503  0.366
2019 Vogel J, Thiel CS, Tauber S, Stockmann C, Gassmann M, Ullrich O. Expression of Hypoxia-Inducible Factor 1α (HIF-1α) and Genes of Related Pathways in Altered Gravity. International Journal of Molecular Sciences. 20. PMID 30669540 DOI: 10.3390/Ijms20020436  0.626
2019 Skaria T, Mitchell K, Fischer JA, Born W, Gassmann M, Vogel J. P4475Vasodilation- and blood pressure normalization-independent cardioprotective effects of endogenous, physical activity-induced alpha calcitonin gene-related peptide in chronic hypertension European Heart Journal. 40. DOI: 10.1093/Eurheartj/Ehz745.0870  0.632
2018 Daryadel A, Bettoni C, Haider T, Imenez Silva PH, Schnitzbauer U, Pastor-Arroyo EM, Wenger RH, Gassmann M, Wagner CA. Erythropoietin stimulates fibroblast growth factor 23 (FGF23) in mice and men. Pflugers Archiv : European Journal of Physiology. PMID 29961920 DOI: 10.1007/S00424-018-2171-7  0.309
2018 Singh RP, Grinenko T, Ramasz B, Franke K, Lesche M, Dahl A, Gassmann M, Chavakis T, Henry I, Wielockx B. Hematopoietic Stem Cells but Not Multipotent Progenitors Drive Erythropoiesis during Chronic Erythroid Stress in EPO Transgenic Mice. Stem Cell Reports. PMID 29754961 DOI: 10.1016/J.Stemcr.2018.04.012  0.312
2018 Bächinger D, Horvath L, Eckhard A, Goosmann MM, Honegger T, Gassmann M, Vogel J, Naldi AM. Neuronal erythropoietin overexpression is protective against kanamycin-induced hearing loss in mice. Toxicology Letters. 291: 121-128. PMID 29654830 DOI: 10.1016/J.Toxlet.2018.04.007  0.626
2017 Tavakoli R, Nemska S, Jamshidi P, Gassmann M, Frossard N. Technique of Minimally Invasive Transverse Aortic Constriction in Mice for Induction of Left Ventricular Hypertrophy. Journal of Visualized Experiments : Jove. PMID 28994784 DOI: 10.3791/56231  0.307
2017 Gilboa D, Haim-Ohana Y, Deshet-Unger N, Ben-Califa N, Hiram-Bab S, Reuveni D, Zigmond E, Gassmann M, Gabet Y, Varol C, Neumann D. Erythropoietin enhances Kupffer cell number and activity in the challenged liver. Scientific Reports. 7: 10379. PMID 28871174 DOI: 10.1038/S41598-017-11082-7  0.313
2017 Schuoler C, Haider TJ, Leuenberger C, Vogel J, Ostergaard L, Kwapiszewska G, Kohler M, Gassmann M, Huber LC, Brock M. Aquaporin 1 controls the functional phenotype of pulmonary smooth muscle cells in hypoxia-induced pulmonary hypertension. Basic Research in Cardiology. 112: 30. PMID 28409279 DOI: 10.1007/S00395-017-0620-7  0.646
2017 Brock M, Schuoler C, Leuenberger C, Bühlmann C, Haider TJ, Vogel J, Ulrich S, Gassmann M, Kohler M, Huber LC. Analysis of hypoxia-induced noncoding RNAs reveals metastasis-associated lung adenocarcinoma transcript 1 as an important regulator of vascular smooth muscle cell proliferation. Experimental Biology and Medicine (Maywood, N.J.). 1535370216685434. PMID 28056547 DOI: 10.1177/1535370216685434  0.632
2016 Rahmig S, Kronstein-Wiedemann R, Fohgrub J, Kronstein N, Nevmerzhitskaya A, Bornhäuser M, Gassmann M, Platz A, Ordemann R, Tonn T, Waskow C. Improved Human Erythropoiesis and Platelet Formation in Humanized NSGW41 Mice. Stem Cell Reports. PMID 27618723 DOI: 10.1016/J.Stemcr.2016.08.005  0.312
2016 Laouafa S, Elliot-Portal E, Revollo S, Schneider Gasser EM, Joseph V, Voituron N, Gassmann M, Soliz J. Hypercapnic ventilatory response is decreased in a mouse model of excessive erythrocytosis. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. ajpregu.00226.2016. PMID 27605561 DOI: 10.1152/Ajpregu.00226.2016  0.38
2016 Gassmann NN, van Elteren HA, Goos TG, Morales CR, Rivera M, Martin DS, Cabala Peralta P, Passano Del Carpio A, Aranibar Machaca S, Huicho L, Reiss IK, Gassmann M, de Jonge RC. Pregnancy at high altitude in the Andes leads to increased total vessel density in healthy newborns. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.00561.2016. PMID 27445300 DOI: 10.1152/Japplphysiol.00561.2016  0.304
2016 Güntert T, Gassmann M, Ogunshola OO. Temporal Rac1 - HIF-1 crosstalk modulates hypoxic survival of aged neurons. Brain Research. PMID 27018294 DOI: 10.1016/J.Brainres.2016.03.025  0.332
2016 Schuoler C, Haider T, Leuenberger C, Vogel J, Ostergaard L, Kohler M, Gassmann M, Huber L, Brock M. Targeting aquaporin 1 reverses hypoxia-induced pulmonary hypertension in mice European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Pa5104  0.64
2016 Brock M, Schuoler C, Haider T, Ulrich S, Gassmann M, Kohler M, Huber L. Detection and characterization of long noncoding RNAs in hypoxia-induced pulmonary hypertension European Respiratory Journal. 48. DOI: 10.1183/13993003.Congress-2016.Oa3009  0.356
2015 Monge Naldi A, Belfrage C, Jain N, Wei ET, Canto Martorell B, Gassmann M, Vogel J. Neuronal erythropoietin overexpression protects mice against age-related hearing loss (presbycusis). Neurobiology of Aging. PMID 26364734 DOI: 10.1016/J.Neurobiolaging.2015.08.015  0.617
2015 Engelhardt S, Huang SF, Patkar S, Gassmann M, Ogunshola OO. Differential responses of blood-brain barrier associated cells to hypoxia and ischemia: a comparative study. Fluids and Barriers of the Cns. 12: 4. PMID 25879623 DOI: 10.1186/2045-8118-12-4  0.364
2015 Huber LC, Ulrich S, Leuenberger C, Gassmann M, Vogel J, von Blotzheim LG, Speich R, Kohler M, Brock M. microRNA-125a in pulmonary hypertension: Regulator of a proliferative phenotype of endothelial cells. Experimental Biology and Medicine (Maywood, N.J.). PMID 25854878 DOI: 10.1177/1535370215579018  0.596
2015 Guo W, Bachman E, Vogel J, Li M, Peng L, Pencina K, Serra C, Sandor NL, Jasuja R, Montano M, Basaria S, Gassmann M, Bhasin S. The effects of short-term and long-term testosterone supplementation on blood viscosity and erythrocyte deformability in healthy adult mice. Endocrinology. 156: 1623-9. PMID 25774550 DOI: 10.1210/En.2014-1784  0.583
2015 Cathomas F, Stegen M, Sigrist H, Schmid L, Seifritz E, Gassmann M, Bettler B, Pryce CR. Altered emotionality and neuronal excitability in mice lacking KCTD12, an auxiliary subunit of GABAB receptors associated with mood disorders. Translational Psychiatry. 5: e510. PMID 25689571 DOI: 10.1038/Tp.2015.8  0.309
2015 Brock M, Haider TJ, Vogel J, Gassmann M, Speich R, Trenkmann M, Ulrich S, Kohler M, Huber LC. The hypoxia-induced microRNA-130a controls pulmonary smooth muscle cell proliferation by directly targeting CDKN1A. The International Journal of Biochemistry & Cell Biology. 61: 129-37. PMID 25681685 DOI: 10.1016/J.Biocel.2015.02.002  0.592
2015 Gammella E, Diaz V, Recalcati S, Buratti P, Samaja M, Dey S, Noguchi CT, Gassmann M, Cairo G. Erythropoietin's inhibiting impact on hepcidin expression occurs indirectly. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 308: R330-5. PMID 25519735 DOI: 10.1152/Ajpregu.00410.2014  0.332
2015 Schuoler C, Haider T, Leuenberger C, Gassmann M, Kohler M, Huber L, Brock M. Expression and function of aquaporin 1 in hypoxia-induced pulmonary hypertension European Respiratory Journal. 46. DOI: 10.1183/13993003.Congress-2015.Pa4906  0.376
2015 Oster HS, Deshet-Unger N, Gassmann M, Mittelman M, Neumann D. Erythropoietin May Affect B-Cell Maturation and Plasma Cell Antibody Production in Mice Blood. 126: 4620-4620. DOI: 10.1182/Blood.V126.23.4620.4620  0.305
2014 Deindl P, Klar M, Drews D, Cremer M, Gammella E, Gassmann M, Dame C. Mice over-expressing human erythropoietin indicate that erythropoietin enhances expression of its receptor via up-regulated Gata1 and Tal1. Haematologica. 99: e205-7. PMID 25085352 DOI: 10.3324/Haematol.2014.104844  0.326
2014 Hänggi P, Makhro A, Gassmann M, Schmugge M, Goede JS, Speer O, Bogdanova A. Red blood cells of sickle cell disease patients exhibit abnormally high abundance of N-methyl D-aspartate receptors mediating excessive calcium uptake. British Journal of Haematology. 167: 252-64. PMID 25041184 DOI: 10.1111/Bjh.13028  0.326
2014 Schuler B, Rieger G, Gubser M, Arras M, Gianella M, Vogel O, Jirkof P, Cesarovic N, Klohs J, Jakob P, Brock M, Gorr TA, Baum O, Hoppeler H, Samillan-Soto V, ... Gassmann M, et al. Endogenous α-calcitonin-gene-related peptide promotes exercise-induced, physiological heart hypertrophy in mice. Acta Physiologica (Oxford, England). 211: 107-21. PMID 24479375 DOI: 10.1111/Apha.12244  0.598
2014 Engelhardt S, Al-Ahmad AJ, Gassmann M, Ogunshola OO. Hypoxia selectively disrupts brain microvascular endothelial tight junction complexes through a hypoxia-inducible factor-1 (HIF-1) dependent mechanism. Journal of Cellular Physiology. 229: 1096-105. PMID 24375098 DOI: 10.1002/Jcp.24544  0.376
2014 Gilboa D, Ohana Haim Y, Deshet N, Gross M, Ben-Califa N, Gassmann M, Souroujon MC, Mittelman M, Neumann D. Liver Macrophages (Kupffer cells) As Novel Targets of Erythropoietin Blood. 124: 4351-4351. DOI: 10.1182/Blood.V124.21.4351.4351  0.361
2013 Samillan V, Haider T, Vogel J, Leuenberger C, Brock M, Schwarzwald C, Gassmann M, Ostergaard L. Combination of erythropoietin and sildenafil can effectively attenuate hypoxia-induced pulmonary hypertension in mice. Pulmonary Circulation. 3: 898-907. PMID 25006406 DOI: 10.1086/674758  0.631
2013 Wang Z, Vogel O, Kuhn G, Gassmann M, Vogel J. Decreased stability of erythroblastic islands in integrin β3-deficient mice. Physiological Reports. 1: e00018. PMID 24303107 DOI: 10.1002/Phy2.18  0.638
2013 Makhro A, Hänggi P, Goede JS, Wang J, Brüggemann A, Gassmann M, Schmugge M, Kaestner L, Speer O, Bogdanova A. N-methyl-D-aspartate receptors in human erythroid precursor cells and in circulating red blood cells contribute to the intracellular calcium regulation. American Journal of Physiology. Cell Physiology. 305: C1123-38. PMID 24048732 DOI: 10.1152/Ajpcell.00031.2013  0.311
2013 Ogunshola OO, Moransard M, Gassmann M. Constitutive excessive erythrocytosis causes inflammation and increased vascular permeability in aged mouse brain. Brain Research. 1531: 48-57. PMID 23892106 DOI: 10.1016/J.Brainres.2013.07.033  0.349
2013 Mey L, Hörmann M, Schleicher N, Reuter P, Dönges S, Kinscherf R, Gassmann M, Gerriets T, Al-Fakhri N. Neuropilin-1 modulates vascular endothelial growth factor-induced poly(ADP-ribose)-polymerase leading to reduced cerebrovascular apoptosis. Neurobiology of Disease. 59: 111-25. PMID 23816753 DOI: 10.1016/J.Nbd.2013.06.009  0.315
2013 Díaz V, Gammella E, Recalcati S, Santambrogio P, Naldi AM, Vogel J, Gassmann M, Cairo G. Liver iron modulates hepcidin expression during chronically elevated erythropoiesis in mice. Hepatology (Baltimore, Md.). 58: 2122-32. PMID 23744538 DOI: 10.1002/Hep.26550  0.586
2013 Franke K, Gassmann M, Wielockx B. Erythrocytosis: the HIF pathway in control. Blood. 122: 1122-8. PMID 23733342 DOI: 10.1182/Blood-2013-01-478065  0.344
2013 Franke K, Kalucka J, Mamlouk S, Singh RP, Muschter A, Weidemann A, Iyengar V, Jahn S, Wieczorek K, Geiger K, Muders M, Sykes AM, Poitz DM, Ripich T, Otto T, ... ... Gassmann M, et al. HIF-1α is a protective factor in conditional PHD2-deficient mice suffering from severe HIF-2α-induced excessive erythropoiesis. Blood. 121: 1436-45. PMID 23264599 DOI: 10.1182/Blood-2012-08-449181  0.389
2013 Gammella E, Leuenberger C, Gassmann M, Ostergaard L. Evidence of synergistic/additive effects of sildenafil and erythropoietin in enhancing survival and migration of hypoxic endothelial cells. American Journal of Physiology. Lung Cellular and Molecular Physiology. 304: L230-9. PMID 23204066 DOI: 10.1152/Ajplung.00112.2012  0.338
2012 van Patot MC, Ebensperger G, Gassmann M, Llanos AJ. The hypoxic placenta. High Altitude Medicine & Biology. 13: 176-84. PMID 22994517 DOI: 10.1089/Ham.2012.1046  0.311
2012 Schuler B, Vogel J, Grenacher B, Jacobs RA, Arras M, Gassmann M. Acute and chronic elevation of erythropoietin in the brain improves exercise performance in mice without inducing erythropoiesis. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 3884-90. PMID 22683849 DOI: 10.1096/Fj.11-191197  0.623
2012 Al Ahmad A, Gassmann M, Ogunshola OO. Involvement of oxidative stress in hypoxia-induced blood-brain barrier breakdown. Microvascular Research. 84: 222-5. PMID 22668821 DOI: 10.1016/J.Mvr.2012.05.008  0.326
2012 Hümmler N, Schneider C, Giessl A, Bauer R, Walkinshaw G, Gassmann M, Rascher W, Trollmann R. Acute hypoxia modifies regulation of neuroglobin in the neonatal mouse brain. Experimental Neurology. 236: 112-21. PMID 22548980 DOI: 10.1016/J.Expneurol.2012.04.006  0.356
2012 Jia Y, Suzuki N, Yamamoto M, Gassmann M, Noguchi CT. Endogenous erythropoietin signaling facilitates skeletal muscle repair and recovery following pharmacologically induced damage. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2847-58. PMID 22490927 DOI: 10.1096/Fj.11-196618  0.303
2012 Gassmann M, Ogunshola OO, Tissot van Patot M. The impact of hypoxia on cells, mice, and men. High Altitude Medicine & Biology. 13: 63-4. PMID 22429236 DOI: 10.1089/Ham.2011.1108  0.355
2012 Schneider C, Krischke G, Rascher W, Gassmann M, Trollmann R. Systemic hypoxia differentially affects neurogenesis during early mouse brain maturation. Brain & Development. 34: 261-73. PMID 21824737 DOI: 10.1016/J.Braindev.2011.07.006  0.382
2012 Ohana YH, Deshet N, Souroujon M, Gassmann M, Mittelman M, Neumann D. Erythropoietin-Associated Increase in the Proportion of Kupffer Cells Blood. 120: 3266-3266. DOI: 10.1182/Blood.V120.21.3266.3266  0.38
2012 Gassmann M. Blood viscosity limits maximal exercise performance in mice Vascular Pharmacology. 56: 320. DOI: 10.1016/J.Vph.2011.08.043  0.314
2011 Hu J, Stiehl DP, Setzer C, Wichmann D, Shinde DA, Rehrauer H, Hradecky P, Gassmann M, Gorr TA. Interaction of HIF and USF signaling pathways in human genes flanked by hypoxia-response elements and E-box palindromes. Molecular Cancer Research : McR. 9: 1520-36. PMID 21984181 DOI: 10.1158/1541-7786.Mcr-11-0090  0.341
2011 Kristiansen G, Hu J, Wichmann D, Stiehl DP, Rose M, Gerhardt J, Bohnert A, ten Haaf A, Moch H, Raleigh J, Varia MA, Subarsky P, Scandurra FM, Gnaiger E, Gleixner E, ... ... Gassmann M, et al. Endogenous myoglobin in breast cancer is hypoxia-inducible by alternative transcription and functions to impair mitochondrial activity: a role in tumor suppression? The Journal of Biological Chemistry. 286: 43417-28. PMID 21930697 DOI: 10.1074/Jbc.M111.227553  0.319
2011 Parathath S, Mick SL, Feig JE, Joaquin V, Grauer L, Habiel DM, Gassmann M, Gardner LB, Fisher EA. Hypoxia is present in murine atherosclerotic plaques and has multiple adverse effects on macrophage lipid metabolism. Circulation Research. 109: 1141-52. PMID 21921268 DOI: 10.1161/Circresaha.111.246363  0.368
2011 Richter V, Savery MD, Gassmann M, Baum O, Damiano ER, Pries AR. Excessive erythrocytosis compromises the blood-endothelium interface in erythropoietin-overexpressing mice. The Journal of Physiology. 589: 5181-92. PMID 21859826 DOI: 10.1113/Jphysiol.2011.209262  0.346
2011 Vogel J, Gassmann M. Erythropoietic and non-erythropoietic functions of erythropoietin in mouse models. The Journal of Physiology. 589: 1259-64. PMID 21282290 DOI: 10.1113/Jphysiol.2010.196147  0.627
2011 Al Ahmad A, Taboada CB, Gassmann M, Ogunshola OO. Astrocytes and pericytes differentially modulate blood-brain barrier characteristics during development and hypoxic insult. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 31: 693-705. PMID 20827262 DOI: 10.1038/Jcbfm.2010.148  0.318
2011 Østergaard L, Gassmann M. Hypoxia inducible factor and hypoxia-mediated pulmonary hypertension Pvri Review. 3: 5-11. DOI: 10.4103/0974-6013.85613  0.32
2010 Trollmann R, Rehrauer H, Schneider C, Krischke G, Huemmler N, Keller S, Rascher W, Gassmann M. Late-gestational systemic hypoxia leads to a similar early gene response in mouse placenta and developing brain. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 299: R1489-99. PMID 20926767 DOI: 10.1152/Ajpregu.00697.2009  0.356
2010 Gassmann M, Pfistner C, Doan VD, Vogel J, Soliz J. Impaired ventilatory acclimatization to hypoxia in female mice overexpressing erythropoietin: unexpected deleterious effect of estradiol in carotid bodies. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 299: R1511-20. PMID 20861276 DOI: 10.1152/Ajpregu.00205.2010  0.643
2010 Lifshitz L, Tabak G, Gassmann M, Mittelman M, Neumann D. Macrophages as novel target cells for erythropoietin. Haematologica. 95: 1823-31. PMID 20595096 DOI: 10.3324/Haematol.2010.025015  0.339
2010 López-Barneo J, Nurse CA, Nilsson GE, Buck LT, Gassmann M, Bogdanova AY. First aid kit for hypoxic survival: sensors and strategies. Physiological and Biochemical Zoology : Pbz. 83: 753-63. PMID 20578845 DOI: 10.1086/651584  0.319
2010 Gorr TA, Wichmann D, Hu J, Hermes-Lima M, Welker AF, Terwilliger N, Wren JF, Viney M, Morris S, Nilsson GE, Deten A, Soliz J, Gassmann M. Hypoxia tolerance in animals: biology and application. Physiological and Biochemical Zoology : Pbz. 83: 733-52. PMID 20565233 DOI: 10.1086/648581  0.348
2010 Makhro A, Wang J, Vogel J, Boldyrev AA, Gassmann M, Kaestner L, Bogdanova A. Functional NMDA receptors in rat erythrocytes. American Journal of Physiology. Cell Physiology. 298: C1315-25. PMID 20457837 DOI: 10.1152/Ajpcell.00407.2009  0.57
2010 Bogdanova A, Heinicke I, Gassmann M, Heinicke K. Oxygen-induced regulation of the intracellular glutathione levels in erythrocytes. European Journal of Applied Physiology. 109: 575-6. PMID 20091336 DOI: 10.1007/S00421-010-1354-5  0.318
2010 Katz O, Stuible M, Golishevski N, Lifshitz L, Tremblay ML, Gassmann M, Mittelman M, Neumann D. Erythropoietin treatment leads to reduced blood glucose levels and body mass: insights from murine models. The Journal of Endocrinology. 205: 87-95. PMID 20061512 DOI: 10.1677/Joe-09-0425  0.357
2010 Schuler B, Arras M, Keller S, Rettich A, Lundby C, Vogel J, Gassmann M. Optimal hematocrit for maximal exercise performance in acute and chronic erythropoietin-treated mice. Proceedings of the National Academy of Sciences of the United States of America. 107: 419-23. PMID 19966291 DOI: 10.1073/Pnas.0912924107  0.613
2010 Kristiansen GO, Hu J, Gerhardt J, Fritzsche F, Theurillat J, Geisler C, Rose M, Stiehl D, Gleixner EM, Hankeln T, Gnaiger E, Moch H, Gassmann M, Gorr T, Dahl E. Abstract 440: Myoglobin in breast cancer: Regulation, function and relevance Cancer Research. 70: 440-440. DOI: 10.1158/1538-7445.Am10-440  0.306
2009 Gassmann M, Tissot van Patot M, Soliz J. The neuronal control of hypoxic ventilation: erythropoietin and sexual dimorphism. Annals of the New York Academy of Sciences. 1177: 151-61. PMID 19845617 DOI: 10.1111/J.1749-6632.2009.05028.X  0.347
2009 Monge Naldi A, Gassmann M, Bodmer D. Erythropoietin but not VEGF has a protective effect on auditory hair cells in the inner ear. Cellular and Molecular Life Sciences : Cmls. 66: 3595-9. PMID 19763398 DOI: 10.1007/S00018-009-0144-X  0.325
2009 Gassmann M, Soliz J. Erythropoietin modulates the neural control of hypoxic ventilation. Cellular and Molecular Life Sciences : Cmls. 66: 3575-82. PMID 19756385 DOI: 10.1007/S00018-009-0142-Z  0.303
2009 Gassmann M. The impact of hypoxia on our body: from integrative physiology to human disease. Cellular and Molecular Life Sciences : Cmls. 66: 3537-8. PMID 19730799 DOI: 10.1007/S00018-009-0140-1  0.35
2009 Ribatti D, Crivellato E, Nico B, Guidolin D, Gassmann M, Djonov V. Mast cells and macrophages in duodenal mucosa of mice overexpressing erythropoietin. Journal of Anatomy. 215: 548-54. PMID 19691658 DOI: 10.1111/J.1469-7580.2009.01131.X  0.36
2009 Schuler B, Rettich A, Vogel J, Gassmann M, Arras M. Optimized surgical techniques and postoperative care improve survival rates and permit accurate telemetric recording in exercising mice. Bmc Veterinary Research. 5: 28. PMID 19646283 DOI: 10.1186/1746-6148-5-28  0.611
2009 Fandrey J, Gassmann M. Oxygen sensing and the activation of the hypoxia inducible factor 1 (HIF-1)--invited article. Advances in Experimental Medicine and Biology. 648: 197-206. PMID 19536482 DOI: 10.1007/978-90-481-2259-2_23  0.361
2009 Gassmann M, Grenacher B, Rohde B, Vogel J. Quantifying Western blots: pitfalls of densitometry. Electrophoresis. 30: 1845-55. PMID 19517440 DOI: 10.1002/Elps.200800720  0.557
2009 Mihov D, Vogel J, Gassmann M, Bogdanova A. Erythropoietin activates nitric oxide synthase in murine erythrocytes. American Journal of Physiology. Cell Physiology. 297: C378-88. PMID 19515903 DOI: 10.1152/Ajpcell.00543.2008  0.62
2009 Schneider C, Krischke G, Keller S, Walkinshaw G, Arend M, Rascher W, Gassmann M, Trollmann R. Short-term effects of pharmacologic HIF stabilization on vasoactive and cytotrophic factors in developing mouse brain. Brain Research. 1280: 43-51. PMID 19450570 DOI: 10.1016/J.Brainres.2009.05.023  0.364
2009 Trollmann R, Gassmann M. The role of hypoxia-inducible transcription factors in the hypoxic neonatal brain. Brain & Development. 31: 503-9. PMID 19398180 DOI: 10.1016/J.Braindev.2009.03.007  0.365
2009 Avneon M, Lifshitz L, Katz O, Prutchi-Sagiv S, Gassmann M, Mittelman M, Neumann D. Non-erythroid effects of erythropoietin: are neutrophils a target? Leukemia Research. 33: 1430-2. PMID 19376577 DOI: 10.1016/J.Leukres.2009.03.020  0.375
2009 Soliz J, Thomsen JJ, Soulage C, Lundby C, Gassmann M. Sex-dependent regulation of hypoxic ventilation in mice and humans is mediated by erythropoietin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 296: R1837-46. PMID 19321698 DOI: 10.1152/Ajpregu.90967.2008  0.367
2009 Lifshitz L, Prutchi-Sagiv S, Avneon M, Gassmann M, Mittelman M, Neumann D. Non-erythroid activities of erythropoietin: Functional effects on murine dendritic cells. Molecular Immunology. 46: 713-21. PMID 19027957 DOI: 10.1016/J.Molimm.2008.10.004  0.303
2009 Al Ahmad A, Gassmann M, Ogunshola OO. Maintaining blood-brain barrier integrity: pericytes perform better than astrocytes during prolonged oxygen deprivation. Journal of Cellular Physiology. 218: 612-22. PMID 19016245 DOI: 10.1002/Jcp.21638  0.317
2008 Trollmann R, Strasser K, Keller S, Antoniou X, Grenacher B, Ogunshola OO, Dötsch J, Rascher W, Gassmann M. Placental HIFs as markers of cerebral hypoxic distress in fetal mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R1973-81. PMID 18832080 DOI: 10.1152/Ajpregu.00053.2008  0.374
2008 Schmid-Brunclik N, Bürgi-Taboada C, Antoniou X, Gassmann M, Ogunshola OO. Astrocyte responses to injury: VEGF simultaneously modulates cell death and proliferation. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R864-73. PMID 18614764 DOI: 10.1152/Ajpregu.00536.2007  0.364
2008 Soliz J, Soulage C, Borter E, van Patot MT, Gassmann M. Ventilatory responses to acute and chronic hypoxia are altered in female but not male Paskin-deficient mice. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 295: R649-58. PMID 18509100 DOI: 10.1152/Ajpregu.00876.2007  0.343
2008 Elser M, Borsig L, Hassa PO, Erener S, Messner S, Valovka T, Keller S, Gassmann M, Hottiger MO. Poly(ADP-ribose) polymerase 1 promotes tumor cell survival by coactivating hypoxia-inducible factor-1-dependent gene expression. Molecular Cancer Research : McR. 6: 282-90. PMID 18314489 DOI: 10.1158/1541-7786.Mcr-07-0377  0.384
2008 Trollmann R, Schneider J, Keller S, Strasser K, Wenzel D, Rascher W, Ogunshola OO, Gassmann M. HIF-1-regulated vasoactive systems are differentially involved in acute hypoxic stress responses of the developing brain of newborn mice and are not affected by levetiracetam. Brain Research. 1199: 27-36. PMID 18281021 DOI: 10.1016/J.Brainres.2007.12.069  0.376
2008 Gassmann M, Manini A, Stallmach T, Saam B, Kuhn G, Grenacher B, Bogdanova AY, Vogel J. Abortion in mice with excessive erythrocytosis is due to impaired arteriogenesis of the uterine arcade. Biology of Reproduction. 78: 1049-57. PMID 18256329 DOI: 10.1095/Biolreprod.107.065532  0.617
2008 Heinzer S, Kuhn G, Krucker T, Meyer E, Ulmann-Schuler A, Stampanoni M, Gassmann M, Marti HH, Müller R, Vogel J. Novel three-dimensional analysis tool for vascular trees indicates complete micro-networks, not single capillaries, as the angiogenic endpoint in mice overexpressing human VEGF(165) in the brain. Neuroimage. 39: 1549-58. PMID 18077185 DOI: 10.1016/J.Neuroimage.2007.10.054  0.607
2007 Bavis RW, Powell FL, Bradford A, Hsia CC, Peltonen JE, Soliz J, Zeis B, Fergusson EK, Fu Z, Gassmann M, Kim CB, Maurer J, McGuire M, Miller BM, O'Halloran KD, et al. Respiratory plasticity in response to changes in oxygen supply and demand. Integrative and Comparative Biology. 47: 532-51. PMID 21672862 DOI: 10.1093/Icb/Icm070  0.315
2007 Camici GG, Stallmach T, Hermann M, Hassink R, Doevendans P, Grenacher B, Hirschy A, Vogel J, Lüscher TF, Ruschitzka F, Gassmann M. Constitutively overexpressed erythropoietin reduces infarct size in a mouse model of permanent coronary artery ligation. Methods in Enzymology. 435: 147-55. PMID 17998053 DOI: 10.1016/S0076-6879(07)35008-8  0.61
2007 Soliz J, Soulage C, Hermann DM, Gassmann M. Acute and chronic exposure to hypoxia alters ventilatory pattern but not minute ventilation of mice overexpressing erythropoietin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1702-10. PMID 17652365 DOI: 10.1152/Ajpregu.00350.2007  0.423
2007 Soliz J, Gassmann M, Joseph V. Soluble erythropoietin receptor is present in the mouse brain and is required for the ventilatory acclimatization to hypoxia. The Journal of Physiology. 583: 329-36. PMID 17584830 DOI: 10.1113/Jphysiol.2007.133454  0.377
2007 Föller M, Kasinathan RS, Koka S, Huber SM, Schuler B, Vogel J, Gassmann M, Lang F. Enhanced susceptibility to suicidal death of erythrocytes from transgenic mice overexpressing erythropoietin. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 293: R1127-34. PMID 17567717 DOI: 10.1152/Ajpregu.00110.2007  0.604
2007 Katz O, Gil L, Lifshitz L, Prutchi-Sagiv S, Gassmann M, Mittelman M, Neumann D. Erythropoietin enhances immune responses in mice. European Journal of Immunology. 37: 1584-93. PMID 17458859 DOI: 10.1002/Eji.200637025  0.358
2007 Bogdanova A, Mihov D, Lutz H, Saam B, Gassmann M, Vogel J. Enhanced erythro-phagocytosis in polycythemic mice overexpressing erythropoietin. Blood. 110: 762-9. PMID 17395782 DOI: 10.1182/Blood-2006-12-063602  0.633
2007 Frietsch T, Gassmann M, Groth G, Waschke KF, Vogel J, Cabrales P, Vajkoczi P, Dorn-Beineke A, Intaglietta M, Kerger H. Excessive erythrocytosis does not elevate capillary oxygen delivery in subcutaneous mouse tissue. Microcirculation (New York, N.Y. : 1994). 14: 111-23. PMID 17365666 DOI: 10.1080/10739680601131200  0.633
2007 Ferreira TC, Hertzberg L, Gassmann M, Campos EG. The yeast genome may harbor hypoxia response elements (HRE). Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 146: 255-63. PMID 17035097 DOI: 10.1016/J.Cbpc.2006.08.013  0.322
2007 Frietsch T, Maurer MH, Vogel J, Gassmann M, Kuschinsky W, Waschke KF. Reduced cerebral blood flow but elevated cerebral glucose metabolic rate in erythropoietin overexpressing transgenic mice with excessive erythrocytosis. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 27: 469-76. PMID 16804549 DOI: 10.1038/Sj.Jcbfm.9600360  0.637
2006 Däpp C, Gassmann M, Hoppeler H, Flück M. Hypoxia-induced gene activity in disused oxidative muscle. Advances in Experimental Medicine and Biology. 588: 171-88. PMID 17089889 DOI: 10.1007/978-0-387-34817-9_16  0.366
2006 Grimm C, Wenzel A, Acar N, Keller S, Seeliger M, Gassmann M. Hypoxic preconditioning and erythropoietin protect retinal neurons from degeneration. Advances in Experimental Medicine and Biology. 588: 119-31. PMID 17089884 DOI: 10.1007/978-0-387-34817-9_11  0.353
2006 Fandrey J, Gorr TA, Gassmann M. Regulating cellular oxygen sensing by hydroxylation. Cardiovascular Research. 71: 642-51. PMID 16780822 DOI: 10.1016/J.Cardiores.2006.05.005  0.331
2006 Heinicke K, Baum O, Ogunshola OO, Vogel J, Stallmach T, Wolfer DP, Keller S, Weber K, Wagner PD, Gassmann M, Djonov V. Excessive erythrocytosis in adult mice overexpressing erythropoietin leads to hepatic, renal, neuronal, and muscular degeneration. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 291: R947-56. PMID 16690772 DOI: 10.1152/Ajpregu.00152.2006  0.633
2006 Ateghang B, Wartenberg M, Gassmann M, Sauer H. Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species. Journal of Cell Science. 119: 1043-52. PMID 16507596 DOI: 10.1242/Jcs.02798  0.326
2006 Gorr TA, Gassmann M, Wappner P. Sensing and responding to hypoxia via HIF in model invertebrates. Journal of Insect Physiology. 52: 349-64. PMID 16500673 DOI: 10.1016/J.Jinsphys.2006.01.002  0.363
2006 Lundby C, Gassmann M, Pilegaard H. Regular endurance training reduces the exercise induced HIF-1alpha and HIF-2alpha mRNA expression in human skeletal muscle in normoxic conditions. European Journal of Applied Physiology. 96: 363-9. PMID 16284786 DOI: 10.1007/S00421-005-0085-5  0.308
2006 Ogunshola OO, Djonov V, Staudt R, Vogel J, Gassmann M. Chronic excessive erythrocytosis induces endothelial activation and damage in mouse brain. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R678-84. PMID 16254128 DOI: 10.1152/Ajpregu.00246.2005  0.645
2006 Schäffer L, Vogel J, Breymann C, Gassmann M, Marti HH. Preserved placental oxygenation and development during severe systemic hypoxia. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 290: R844-51. PMID 16195499 DOI: 10.1152/Ajpregu.00237.2005  0.638
2005 Wassel K, Kuhn G, Gassmann M, Vogel J. Permanently increased conductance of the murine uterine arcade after the first pregnancy. European Journal of Morphology. 42: 225-32. PMID 16982480 DOI: 10.1080/09243860600746916  0.604
2005 Weissmann N, Manz D, Buchspies D, Keller S, Mehling T, Voswinckel R, Quanz K, Ghofrani HA, Schermuly RT, Fink L, Seeger W, Gassmann M, Grimminger F. Congenital erythropoietin over-expression causes "anti-pulmonary hypertensive" structural and functional changes in mice, both in normoxia and hypoxia. Thrombosis and Haemostasis. 94: 630-8. PMID 16268482 DOI: 10.1160/Th05-02-0104  0.39
2005 Kilic E, Kilic U, Soliz J, Bassetti CL, Gassmann M, Hermann DM. Brain-derived erythropoietin protects from focal cerebral ischemia by dual activation of ERK-1/-2 and Akt pathways. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 2026-8. PMID 16207820 DOI: 10.1096/Fj.05-3941Fje  0.332
2005 Cramer M, Nagy I, Murphy BJ, Gassmann M, Hottiger MO, Georgiev O, Schaffner W. NF-kappaB contributes to transcription of placenta growth factor and interacts with metal responsive transcription factor-1 in hypoxic human cells. Biological Chemistry. 386: 865-72. PMID 16164411 DOI: 10.1515/Bc.2005.101  0.316
2005 Grimm C, Hermann DM, Bogdanova A, Hotop S, Kilic U, Wenzel A, Kilic E, Gassmann M. Neuroprotection by hypoxic preconditioning: HIF-1 and erythropoietin protect from retinal degeneration. Seminars in Cell & Developmental Biology. 16: 531-8. PMID 16144690 DOI: 10.1016/J.Semcdb.2005.03.004  0.365
2005 Soliz J, Joseph V, Soulage C, Becskei C, Vogel J, Pequignot JM, Ogunshola O, Gassmann M. Erythropoietin regulates hypoxic ventilation in mice by interacting with brainstem and carotid bodies. The Journal of Physiology. 568: 559-71. PMID 16051624 DOI: 10.1113/Jphysiol.2005.093328  0.656
2005 Kilic U, Kilic E, Soliz J, Bassetti CI, Gassmann M, Hermann DM. Erythropoietin protects from axotomy-induced degeneration of retinal ganglion cells by activating ERK-1/-2. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 19: 249-51. PMID 15556972 DOI: 10.1096/Fj.04-2493Fje  0.349
2004 Tang K, Breen EC, Wagner H, Brutsaert TD, Gassmann M, Wagner PD. HIF and VEGF relationships in response to hypoxia and sciatic nerve stimulation in rat gastrocnemius. Respiratory Physiology & Neurobiology. 144: 71-80. PMID 15522704 DOI: 10.1016/J.Resp.2004.04.009  0.322
2004 Pillet S, Le Guyader N, Hofer T, NguyenKhac F, Koken M, Aubin JT, Fichelson S, Gassmann M, Morinet F. Hypoxia enhances human B19 erythrovirus gene expression in primary erythroid cells. Virology. 327: 1-7. PMID 15327892 DOI: 10.1016/J.Virol.2004.06.020  0.34
2004 Distler O, Distler JH, Scheid A, Acker T, Hirth A, Rethage J, Michel BA, Gay RE, Müller-Ladner U, Matucci-Cerinic M, Plate KH, Gassmann M, Gay S. Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis. Circulation Research. 95: 109-16. PMID 15178641 DOI: 10.1161/01.Res.0000134644.89917.96  0.319
2004 Waskow C, Terszowski G, Costa C, Gassmann M, Rodewald HR. Rescue of lethal c-KitW/W mice by erythropoietin. Blood. 104: 1688-95. PMID 15178584 DOI: 10.1182/Blood-2004-04-1247  0.324
2004 Höpfl G, Ogunshola O, Gassmann M. HIFs and tumors--causes and consequences. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 286: R608-23. PMID 15003941 DOI: 10.1152/Ajpregu.00538.2003  0.341
2004 Vogel J, Gassmann M. Adaptive mechanisms in mice constitutively overexpressing erythropoietin International Congress Series. 1275: 63-70. DOI: 10.1016/j.ics.2004.08.091  0.585
2003 Gassmann M, Heinicke K, Soliz J, Ogunshola OO. Non-erythroid functions of erythropoietin. Advances in Experimental Medicine and Biology. 543: 323-30. PMID 14713131 DOI: 10.1007/978-1-4419-8997-0_22  0.324
2003 Höpfl G, Ogunshola O, Gassmann M. Hypoxia and high altitude. The molecular response. Advances in Experimental Medicine and Biology. 543: 89-115. PMID 14713116 DOI: 10.1007/978-1-4419-8997-0_7  0.358
2003 Koshikawa N, Iyozumi A, Gassmann M, Takenaga K. Constitutive upregulation of hypoxia-inducible factor-1alpha mRNA occurring in highly metastatic lung carcinoma cells leads to vascular endothelial growth factor overexpression upon hypoxic exposure. Oncogene. 22: 6717-24. PMID 14555985 DOI: 10.1038/Sj.Onc.1206765  0.323
2003 Bogdanova AY, Ogunshola OO, Bauer C, Gassmann M. Pivotal role of reduced glutathione in oxygen-induced regulation of the Na(+)/K(+) pump in mouse erythrocyte membranes. The Journal of Membrane Biology. 195: 33-42. PMID 14502424 DOI: 10.1007/S00232-003-2042-8  0.321
2003 Katschinski DM, Marti HH, Wagner KF, Shibata J, Eckhardt K, Martin F, Depping R, Paasch U, Gassmann M, Ledermann B, Desbaillets I, Wenger RH. Targeted disruption of the mouse PAS domain serine/threonine kinase PASKIN. Molecular and Cellular Biology. 23: 6780-9. PMID 12972598 DOI: 10.1128/Mcb.23.19.6780-6789.2003  0.326
2003 Tomita S, Ueno M, Sakamoto M, Kitahama Y, Ueki M, Maekawa N, Sakamoto H, Gassmann M, Kageyama R, Ueda N, Gonzalez FJ, Takahama Y. Defective brain development in mice lacking the Hif-1alpha gene in neural cells. Molecular and Cellular Biology. 23: 6739-49. PMID 12972594 DOI: 10.1128/Mcb.23.19.6739-6749.2003  0.367
2003 Vogel J, Kiessling I, Heinicke K, Stallmach T, Ossent P, Vogel O, Aulmann M, Frietsch T, Schmid-Schönbein H, Kuschinsky W, Gassmann M. Transgenic mice overexpressing erythropoietin adapt to excessive erythrocytosis by regulating blood viscosity. Blood. 102: 2278-84. PMID 12750170 DOI: 10.1182/Blood-2003-01-0283  0.647
2003 Shibata J, Hasegawa J, Siemens HJ, Wolber E, Dibbelt L, Li D, Katschinski DM, Fandrey J, Jelkmann W, Gassmann M, Wenger RH, Wagner KF. Hemostasis and coagulation at a hematocrit level of 0.85: functional consequences of erythrocytosis. Blood. 101: 4416-22. PMID 12576335 DOI: 10.1182/Blood-2002-09-2814  0.376
2003 Wartenberg M, Ling FC, Müschen M, Klein F, Acker H, Gassmann M, Petrat K, Pütz V, Hescheler J, Sauer H. Regulation of the multidrug resistance transporter P-glycoprotein in multicellular tumor spheroids by hypoxia-inducible factor (HIF-1) and reactive oxygen species. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 503-5. PMID 12514119 DOI: 10.1096/Fj.02-0358Fje  0.305
2003 Quaschning T, Ruschitzka F, Stallmach T, Shaw S, Morawietz H, Goettsch W, Hermann M, Slowinski T, Theuring F, Hocher B, Lüscher TF, Gassmann M. Erythropoietin-induced excessive erythrocytosis activates the tissue endothelin system in mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 259-61. PMID 12490547 DOI: 10.1096/Fj.02-0296Fje  0.349
2003 Hofer T, Wenger RH, Kramer MF, Ferreira GC, Gassmann M. Hypoxic up-regulation of erythroid 5-aminolevulinate synthase. Blood. 101: 348-50. PMID 12393745 DOI: 10.1182/Blood-2002-03-0773  0.347
2002 Hofer T, Desbaillets I, Höpfl G, Wenger RH, Gassmann M. Characterization of HIF-1 alpha overexpressing HeLa cells and implications for gene therapy. Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp. 133: 475-81. PMID 12458176 DOI: 10.1016/S1532-0456(02)00117-5  0.368
2002 Enomoto N, Koshikawa N, Gassmann M, Hayashi J, Takenaga K. Hypoxic induction of hypoxia-inducible factor-1alpha and oxygen-regulated gene expression in mitochondrial DNA-depleted HeLa cells. Biochemical and Biophysical Research Communications. 297: 346-52. PMID 12237125 DOI: 10.1016/S0006-291X(02)02186-1  0.37
2002 Rose F, Grimminger F, Appel J, Heller M, Pies V, Weissmann N, Fink L, Schmidt S, Krick S, Camenisch G, Gassmann M, Seeger W, Hänze J. Hypoxic pulmonary artery fibroblasts trigger proliferation of vascular smooth muscle cells: role of hypoxia-inducible transcription factors. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 16: 1660-1. PMID 12207001 DOI: 10.1096/Fj.02-0420Fje  0.337
2002 Slowinski T, Schulz N, Ruschitzka FT, Quaschning T, Bauer C, Theuring F, Neumayer HH, Gassmann M, Hocher B. Pattern of prepro-endothelin-1 expression revealed by reporter-gene activity in kidneys of erythropoietin-overexpressing mice. Clinical Science (London, England : 1979). 103: 44S-47S. PMID 12193052 DOI: 10.1042/Cs103S044S  0.374
2002 Maurer MH, Frietsch T, Waschke KF, Kuschinsky W, Gassmann M, Schneider A. Cerebral transcriptome analysis of transgenic mice overexpressing erythropoietin. Neuroscience Letters. 327: 181-4. PMID 12113907 DOI: 10.1016/S0304-3940(02)00425-1  0.344
2002 Höpfl G, Wenger RH, Ziegler U, Stallmach T, Gardelle O, Achermann R, Wergin M, Kaser-Hotz B, Saunders HM, Williams KJ, Stratford IJ, Gassmann M, Desbaillets I. Rescue of Hypoxia-inducible Factor-1α-deficient Tumor Growth by Wild-Type Cells Is Independent of Vascular Endothelial Growth Factor Cancer Research. 62: 2962-2970. DOI: 10.5167/Uzh-12  0.308
2002 Distler O, Scheid A, Rosso AD, Rethage J, Neidhart M, Gay R, Müller-Ladner U, Gassmann M, Matucci-Cerinic M, Gay S. Arthritis Research. 4: 1. DOI: 10.1186/Ar433  0.302
2002 Frietsch T, Maurer MH, Fütterer CD, Gassmann M, Waschke KF. Hemoglobin Is Expressed by Neurons in the Brain of Transgenic Mice Overexpressing Erythropoietin (EPO) Anesthesiology. 96: A761. DOI: 10.1097/00000542-200209002-00761  0.331
2001 Chilov D, Hofer T, Bauer C, Wenger RH, Gassmann M. Hypoxia affects expression of circadian genes PER1 and CLOCK in mouse brain. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2613-22. PMID 11726537 DOI: 10.1096/Fj.01-0092Com  0.353
2001 Hofer T, Desbaillets I, Höpfl G, Gassmann M, Wenger RH. Dissecting hypoxia-dependent and hypoxia-independent steps in the HIF-1alpha activation cascade: implications for HIF-1alpha gene therapy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 15: 2715-7. PMID 11606485 DOI: 10.1096/Fj.01-0546Fje  0.317
2001 Wiessner C, Allegrini PR, Ekatodramis D, Jewell UR, Stallmach T, Gassmann M. Increased cerebral infarct volumes in polyglobulic mice overexpressing erythropoietin. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 21: 857-64. PMID 11435798 DOI: 10.1097/00004647-200107000-00011  0.37
2001 Wagner KF, Katschinski DM, Hasegawa J, Schumacher D, Meller B, Gembruch U, Schramm U, Jelkmann W, Gassmann M, Fandrey J. Chronic inborn erythrocytosis leads to cardiac dysfunction and premature death in mice overexpressing erythropoietin. Blood. 97: 536-42. PMID 11154234 DOI: 10.1182/Blood.V97.2.536  0.389
2000 Ruschitzka FT, Wenger RH, Stallmach T, Quaschning T, de Wit C, Wagner K, Labugger R, Kelm M, Noll G, Rülicke T, Shaw S, Lindberg RL, Rodenwaldt B, Lutz H, Bauer C, ... ... Gassmann M, et al. Nitric oxide prevents cardiovascular disease and determines survival in polyglobulic mice overexpressing erythropoietin. Proceedings of the National Academy of Sciences of the United States of America. 97: 11609-13. PMID 11027359 DOI: 10.1073/Pnas.97.21.11609  0.389
2000 Görlach A, Camenisch G, Kvietikova I, Vogt L, Wenger RH, Gassmann M. Efficient translation of mouse hypoxia-inducible factor-1alpha under normoxic and hypoxic conditions. Biochimica Et Biophysica Acta. 1493: 125-34. PMID 10978514 DOI: 10.1016/S0167-4781(00)00172-X  0.328
2000 Gassmann M, Chilov D, Wenger RH. Regulation of the hypoxia-inducible factor-1 alpha. ARNT is not necessary for hypoxic induction of HIF-1 alpha in the nucleus. Advances in Experimental Medicine and Biology. 475: 87-99. PMID 10849651 DOI: 10.1007/0-306-46825-5_9  0.344
2000 Garayoa M, Martínez A, Lee S, Pío R, An WG, Neckers L, Trepel J, Montuenga LM, Ryan H, Johnson R, Gassmann M, Cuttitta F. Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis. Molecular Endocrinology (Baltimore, Md.). 14: 848-62. PMID 10847587 DOI: 10.1210/Mend.14.6.0473  0.36
2000 Pavlicek V, Marti HH, Grad S, Gibbs JS, Kol C, Wenger RH, Gassmann M, Kohl J, Maly FE, Oelz O, Koller EA, Schirlo C. Effects of hypobaric hypoxia on vascular endothelial growth factor and the acute phase response in subjects who are susceptible to high-altitude pulmonary oedema. European Journal of Applied Physiology. 81: 497-503. PMID 10774874 DOI: 10.1007/S004210050074  0.323
2000 Wanner RM, Spielmann P, Stroka DM, Camenisch G, Camenisch I, Scheid A, Houck DR, Bauer C, Gassmann M, Wenger RH. Epolones induce erythropoietin expression via hypoxia-inducible factor-1α activation Blood. 96: 1558-1565. DOI: 10.1182/Blood.V96.4.1558.H8001558_1558_1565  0.336
1998 Gassmann M, Hennet T. From Genetically Altered Mice to Integrative Physiology. News in Physiological Sciences : An International Journal of Physiology Produced Jointly by the International Union of Physiological Sciences and the American Physiological Society. 13: 53-57. PMID 11390761 DOI: 10.1152/Physiologyonline.1998.13.2.53  0.327
1998 Wenger RH, Marti HH, Bauer C, Gassmann M. Optimal erythropoietin expression in human hepatoma cell lines requires activation of multiple signalling pathways. International Journal of Molecular Medicine. 2: 317-24. PMID 9855704 DOI: 10.3892/Ijmm.2.3.317  0.358
1998 Wenger RH, Kvietikova I, Rolfs A, Camenisch G, Gassmann M. Oxygen-regulated erythropoietin gene expression is dependent on a CpG methylation-free hypoxia-inducible factor-1 DNA-binding site. European Journal of Biochemistry / Febs. 253: 771-7. PMID 9654078 DOI: 10.1046/J.1432-1327.1998.2530771.X  0.319
1998 Wenger RH, Rolfs A, Spielmann P, Zimmermann DR, Gassmann M. Mouse hypoxia-inducible factor-1alpha is encoded by two different mRNA isoforms: expression from a tissue-specific and a housekeeping-type promoter. Blood. 91: 3471-80. PMID 9558407 DOI: 10.1182/Blood.V91.9.3471.3471_3471_3480  0.36
1998 Iyer NV, Kotch LE, Agani F, Leung SW, Laughner E, Wenger RH, Gassmann M, Gearhart JD, Lawler AM, Yu AY, Semenza GL. Cellular and developmental control of O2 homeostasis by hypoxia-inducible factor 1 alpha. Genes & Development. 12: 149-62. PMID 9436976 DOI: 10.1101/Gad.12.2.149  0.354
1997 Rolfs A, Kvietikova I, Gassmann M, Wenger RH. Oxygen-regulated transferrin expression is mediated by hypoxia-inducible factor-1. The Journal of Biological Chemistry. 272: 20055-62. PMID 9242677 DOI: 10.1074/Jbc.272.32.20055  0.365
1997 Wenger RH, Rolfs A, Kvietikova I, Spielmann P, Zimmermann DR, Gassmann M. The mouse gene for hypoxia-inducible factor-1alpha--genomic organization, expression and characterization of an alternative first exon and 5' flanking sequence. European Journal of Biochemistry / Febs. 246: 155-65. PMID 9210478 DOI: 10.1111/J.1432-1033.1997.T01-1-00155.X  0.319
1997 Gassmann M, Kvietikova I, Rolfs A, Wenger RH. Oxygen- and dioxin-regulated gene expression in mouse hepatoma cells. Kidney International. 51: 567-74. PMID 9027741 DOI: 10.1038/Ki.1997.81  0.384
1997 Kvietikova I, Wenger RH, Marti HH, Gassmann M. The hypoxia-inducible factor-1 DNA recognition site is cAMP-responsive. Kidney International. 51: 564-6. PMID 9027740 DOI: 10.1038/Ki.1997.80  0.316
1997 Marti HH, Gassmann M, Wenger RH, Kvietikova I, Morganti-Kossmann MC, Kossmann T, Trentz O, Bauer C. Detection of erythropoietin in human liquor: intrinsic erythropoietin production in the brain. Kidney International. 51: 416-8. PMID 9027715 DOI: 10.1038/Ki.1997.55  0.319
1996 Marti HH, Wenger RH, Rivas LA, Straumann U, Digicaylioglu M, Henn V, Yonekawa Y, Bauer C, Gassmann M. Erythropoietin gene expression in human, monkey and murine brain. The European Journal of Neuroscience. 8: 666-76. PMID 9081618 DOI: 10.1111/J.1460-9568.1996.Tb01252.X  0.356
1996 Gradin K, McGuire J, Wenger RH, Kvietikova I, fhitelaw ML, ToftgÃ¥rd R, Tora L, Gassmann M, Poellinger L. Functional interference between hypoxia and dioxin signal transduction pathways: competition for recruitment of the Arnt transcription factor. Molecular and Cellular Biology. 16: 5221-31. PMID 8816435 DOI: 10.1128/Mcb.16.10.5221  0.314
1996 Wenger RH, Rolfs A, Marti HH, Guénet JL, Gassmann M. Nucleotide sequence, chromosomal assignment and mRNA expression of mouse hypoxia-inducible factor-1 alpha. Biochemical and Biophysical Research Communications. 223: 54-9. PMID 8660378 DOI: 10.1006/Bbrc.1996.0845  0.316
1996 Gassmann M, Fandrey J, Bichet S, Wartenberg M, Marti HH, Bauer C, Wenger RH, Acker H. Oxygen supply and oxygen-dependent gene expression in differentiating embryonic stem cells. Proceedings of the National Academy of Sciences of the United States of America. 93: 2867-72. PMID 8610133 DOI: 10.1073/Pnas.93.7.2867  0.339
1996 Wenger RH, Marti HH, Schuerer-Maly CC, Kvietikova I, Bauer C, Gassmann M, Maly FE. Hypoxic induction of gene expression in chronic granulomatous disease-derived B-cell lines: oxygen sensing is independent of the cytochrome b558-containing nicotinamide adenine dinucleotide phosphate oxidase. Blood. 87: 756-61. PMID 8555500 DOI: 10.1182/Blood.V87.2.756.Bloodjournal872756  0.331
1995 Kvietikova I, Wenger RH, Marti HH, Gassmann M. The transcription factors ATF-1 and CREB-1 bind constitutively to the hypoxia-inducible factor-1 (HIF-1) DNA recognition site. Nucleic Acids Research. 23: 4542-50. PMID 8524640 DOI: 10.1093/Nar/23.22.4542  0.32
1995 Hergersberg M, Matsuo K, Gassmann M, Schaffner W, Lüscher B, Rülicke T, Aguzzi A. Tissue-specific expression of a FMR1/beta-galactosidase fusion gene in transgenic mice. Human Molecular Genetics. 4: 359-66. PMID 7795588 DOI: 10.1093/Hmg/4.3.359  0.325
1995 Digicaylioglu M, Bichet S, Marti HH, Wenger RH, Rivas LA, Bauer C, Gassmann M. Localization of specific erythropoietin binding sites in defined areas of the mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 92: 3717-3720. PMID 7731971 DOI: 10.1073/Pnas.92.9.3717  0.302
1995 Wenger RH, Rolfs A, Marti HH, Bauer C, Gassmann M. Hypoxia, a novel inducer of acute phase gene expression in a human hepatoma cell line. The Journal of Biological Chemistry. 270: 27865-70. PMID 7499259 DOI: 10.1074/Jbc.270.46.27865  0.337
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