| Year |
Citation |
Score |
| 2024 |
Andrews SG, Koehle AM, Paudel D, Neuberger T, Ross AC, Singh V, Bottiglieri T, Castro R. Diet-Induced Severe Hyperhomocysteinemia Promotes Atherosclerosis Progression and Dysregulates the Plasma Metabolome in Apolipoprotein-E-Deficient Mice. Nutrients. 16. PMID 38337615 DOI: 10.3390/nu16030330 |
0.316 |
|
| 2024 |
Leclerc D, Christensen KE, Reagan AM, Keser V, Luan Y, Malysheva OV, Wasek B, Bottiglieri T, Caudill MA, Howell GR, Rozen R. Folate Deficiency and/or the Genetic Variant Mthfr Can Drive Hepatic Fibrosis or Steatosis in Mice, in a Sex-Specific Manner. Molecular Nutrition & Food Research. e2300355. PMID 38327171 DOI: 10.1002/mnfr.202300355 |
0.698 |
|
| 2023 |
Clementson M, Hurley L, Coonrod S, Bennett C, Marella P, Pascual AS, Pull K, Wasek B, Bottiglieri T, Malysheva O, Caudill MA, Jadavji NM. Maternal dietary deficiencies in folic acid or choline worsen stroke outcomes in adult male and female mouse offspring. Neural Regeneration Research. 18: 2443-2448. PMID 37282475 DOI: 10.4103/1673-5374.371375 |
0.788 |
|
| 2023 |
Mbs GBY, Wasek B, Bottiglieri T, Malysheva O, Caudill MA, Jadavji NM. Dietary vitamin B12 deficiency impairs motor function and changes neuronal survival and choline metabolism after ischemic stroke in middle-aged male and female mice. Nutritional Neuroscience. 1-10. PMID 36932327 DOI: 10.1080/1028415X.2023.2188639 |
0.789 |
|
| 2023 |
Lerin C, Collado MC, Isganaitis E, Arning E, Wasek B, Demerath EW, Fields DA, Bottiglieri T. Revisiting One-Carbon Metabolites in Human Breast Milk: Focus on S-Adenosylmethionine. Nutrients. 15. PMID 36678154 DOI: 10.3390/nu15020282 |
0.761 |
|
| 2023 |
Simonian R, Pannia E, Hammoud R, Noche RR, Cui X, Kranenburg E, Kubant R, Ashcraft P, Wasek B, Bottiglieri T, Dowling JJ, Anderson GH. Methylenetetrahydrofolate reductase deficiency and high dose FA supplementation disrupt embryonic development of energy balance and metabolic homeostasis in zebrafish. Human Molecular Genetics. PMID 36637428 DOI: 10.1093/hmg/ddac308 |
0.714 |
|
| 2022 |
Weekman EM, Winder Z, Rogers CB, Abner EL, Sudduth TL, Patel E, Dugan AJ, Fister SX, Wasek B, Nelson PT, Jicha GA, Bottiglieri T, Fardo DW, Wilcock DM. Genetic expression changes and pathologic findings associated with hyperhomocysteinemia in human autopsy brain tissue. Alzheimer's & Dementia (New York, N. Y.). 8: e12368. PMID 36514441 DOI: 10.1002/trc2.12368 |
0.699 |
|
| 2022 |
Shen JS, Balaji U, Shigeyasu K, Okugawa Y, Jabbarzadeh-Tabrizi S, Day TS, Arning E, Marshall J, Cheng SH, Gu J, Schiffmann R, Bottiglieri T, Goel A. Dysregulated DNA methylation in the pathogenesis of Fabry disease. Molecular Genetics and Metabolism Reports. 33: 100919. PMID 36186841 DOI: 10.1016/j.ymgmr.2022.100919 |
0.585 |
|
| 2022 |
Arning E, Wasek B, Bottiglieri T. Quantitation of 5-Methyltetrahydrofolate in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray-Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 2546: 311-319. PMID 36127600 DOI: 10.1007/978-1-0716-2565-1_28 |
0.766 |
|
| 2022 |
Arning E, Wasek B, Bottiglieri T. Quantitation of γ-Aminobutyric Acid in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray-Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 2546: 165-174. PMID 36127587 DOI: 10.1007/978-1-0716-2565-1_15 |
0.754 |
|
| 2022 |
Arning E, Wasek B, Bottiglieri T. Quantification of Plasma S-adenosylmethionine and S-adenosylhomocysteine Using Liquid Chromatography-Electrospray-Tandem Mass Spectrometry. Methods in Molecular Biology (Clifton, N.J.). 2546: 35-43. PMID 36127576 DOI: 10.1007/978-1-0716-2565-1_4 |
0.752 |
|
| 2022 |
Poole J, Jasbi P, Pascual AS, North S, Kwatra N, Weissig V, Gu H, Bottiglieri T, Jadavji NM. Ischemic Stroke and Dietary Vitamin B12 Deficiency in Old-Aged Females: Impaired Motor Function, Increased Ischemic Damage Size, and Changed Metabolite Profiles in Brain and Cecum Tissue. Nutrients. 14. PMID 35889916 DOI: 10.3390/nu14142960 |
0.624 |
|
| 2022 |
Bobrowski-Khoury N, Sequeira JM, Arning E, Bottiglieri T, Quadros EV. Absorption and Tissue Distribution of Folate Forms in Rats: Indications for Specific Folate Form Supplementation during Pregnancy. Nutrients. 14. PMID 35745126 DOI: 10.3390/nu14122397 |
0.593 |
|
| 2022 |
May T, de la Haye B, Nord G, Klatt K, Stephenson K, Adams S, Bollinger L, Hanchard N, Arning E, Bottiglieri T, Maleta K, Manary M, Jahoor F. One-carbon metabolism in children with marasmus and kwashiorkor. Ebiomedicine. 75: 103791. PMID 35030356 DOI: 10.1016/j.ebiom.2021.103791 |
0.565 |
|
| 2022 |
Seaks CE, Weekman EM, Sudduth TL, Xie K, Wasek B, Fardo DW, Johnson LA, Bottiglieri T, Wilcock DM. Apolipoprotein E ε4/4 genotype limits response to dietary induction of hyperhomocysteinemia and resulting inflammatory signaling. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X211069006. PMID 35023380 DOI: 10.1177/0271678X211069006 |
0.726 |
|
| 2021 |
Alam A, Jamil AK, Van Zyl JS, Medel-Martinez H, Bottiglieri T, Wasek B, Felius J, Lima B, Hall SA, Joseph SM. Urinary Cell-Cycle Arrest Biomarkers as Early Predictors of Acute Kidney Injury After Ventricular Assist Device Implantation or Cardiac Transplantation. Journal of Cardiothoracic and Vascular Anesthesia. PMID 34774406 DOI: 10.1053/j.jvca.2021.10.013 |
0.648 |
|
| 2021 |
Bottiglieri T, Wang X, Arning E, Fernandez H, Wall A, McKenna G, Ruiz R, Onaca N, Trotter J, Lawrence M, Naziruddin B, Asrani SK, Testa G. Longitudinal profiling of plasma and urine metabolites during liver regeneration in living liver donors. Clinical Transplantation. e14490. PMID 34545967 DOI: 10.1111/ctr.14490 |
0.568 |
|
| 2021 |
Cedars A, Manlhiot C, Ko JM, Bottiglieri T, Arning E, Weingarten A, Opotowsky A, Kutty S. Metabolomic Profiling of Adults with Congenital Heart Disease. Metabolites. 11. PMID 34436466 DOI: 10.3390/metabo11080525 |
0.6 |
|
| 2021 |
Panetta JC, Liu Y, Bottiglieri T, Arning E, Cheng C, Karol SE, Yang JJ, Zhou Y, Inaba H, Pui CH, Jeha S, Relling MV. Pharmacodynamics of cerebrospinal fluid asparagine after asparaginase. Cancer Chemotherapy and Pharmacology. PMID 34170389 DOI: 10.1007/s00280-021-04315-0 |
0.522 |
|
| 2021 |
Luan Y, Leclerc D, Cosín-Tomás M, Malysheva OV, Wasek B, Bottiglieri T, Caudill MA, Rozen R. Moderate Folic Acid Supplementation in Pregnant Mice Results in Altered Methyl Metabolism and in Sex-specific Placental Transcription Changes. Molecular Nutrition & Food Research. e2100197. PMID 34010503 DOI: 10.1002/mnfr.202100197 |
0.73 |
|
| 2021 |
Gupta S, Wang L, Slifker MJ, Cai KQ, Maclean KN, Wasek B, Bottiglieri T, Kruger WD. Analysis of differential neonatal lethality in cystathionine β-synthase deficient mouse models using metabolic profiling. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 35: e21629. PMID 33949005 DOI: 10.1096/fj.202100302R |
0.724 |
|
| 2021 |
Pannia E, Hammoud R, Kubant R, Sa JY, Simonian R, Wasek B, Ashcraft P, Bottiglieri T, Pausova Z, Anderson GH. High Intakes of [6S]-5-Methyltetrahydrofolic Acid Compared with Folic Acid during Pregnancy Programs Central and Peripheral Mechanisms Favouring Increased Food Intake and Body Weight of Mature Female Offspring. Nutrients. 13. PMID 33925570 DOI: 10.3390/nu13051477 |
0.697 |
|
| 2021 |
Ribo S, Sánchez-Infantes D, Martinez-Guino L, García-Mantrana I, Ramon-Krauel M, Tondo M, Arning E, Nofrarías M, Osorio-Conles Ó, Fernández-Pérez A, González-Torres P, Cebrià J, Gavaldà-Navarro A, Chenoll E, Isganaitis E, ... ... Bottiglieri T, et al. Increasing breast milk betaine modulates abundance in mammalian neonates and improves long-term metabolic health. Science Translational Medicine. 13. PMID 33790021 DOI: 10.1126/scitranslmed.abb0322 |
0.569 |
|
| 2021 |
Hammoud R, Pannia E, Kubant R, Wasek B, Bottiglieri T, Malysheva OV, Caudill MA, Anderson GH. Choline and Folic Acid in Diets Consumed during Pregnancy Interact to Program Food Intake and Metabolic Regulation of Male Wistar Rat Offspring. The Journal of Nutrition. PMID 33561219 DOI: 10.1093/jn/nxaa419 |
0.696 |
|
| 2021 |
Yahn G, Bottiglieri T, Wasek B, Jadavji N. Abstract P807: Vitamin B12 Deficiency Impairs Balance and Coordination After Photothrombotic Damage to the Sensorimotor Cortex in Adult Male and Female Mice After Ischemic Stroke Stroke. 52. DOI: 10.1161/STR.52.SUPPL_1.P807 |
0.64 |
|
| 2020 |
Walters DC, Jansen EEW, Salomons GS, Arning E, Ashcraft P, Bottiglieri T, Roullet JB, Gibson KM. Preferential accumulation of the active S-(+) isomer in murine retina highlights novel mechanisms of vigabatrin-associated retinal toxicity. Epilepsy Research. 170: 106536. PMID 33385945 DOI: 10.1016/j.eplepsyres.2020.106536 |
0.573 |
|
| 2020 |
Pannia E, Hammoud R, Simonian R, Arning E, Ashcraft P, Wasek B, Bottiglieri T, Pausova Z, Kubant R, Anderson GH. [6]-5-Methyltetrahydrofolic Acid and Folic Acid Pregnancy Diets Differentially Program Metabolic Phenotype and Hypothalamic Gene Expression of Wistar Rat Dams Post-Birth. Nutrients. 13. PMID 33375730 DOI: 10.3390/nu13010048 |
0.772 |
|
| 2020 |
Brown MN, Gibson KM, Schmidt MA, Walters DC, Arning E, Bottiglieri T, Roullet JB. Cellular and molecular outcomes of glutamine supplementation in the brain of succinic semialdehyde dehydrogenase-deficient mice. Jimd Reports. 56: 58-69. PMID 33204597 DOI: 10.1002/jmd2.12151 |
0.628 |
|
| 2020 |
Kirby T, Walters DC, Shi X, Turgeon C, Rinaldo P, Arning E, Ashcraft P, Bottiglieri T, DiBacco M, Pearl PL, Roullet JB, Gibson KM. Novel biomarkers and age-related metabolite correlations in plasma and dried blood spots from patients with succinic semialdehyde dehydrogenase deficiency. Orphanet Journal of Rare Diseases. 15: 261. PMID 32967698 DOI: 10.1186/s13023-020-01522-5 |
0.582 |
|
| 2020 |
Christine CW, Auinger P, Saleh N, Tian M, Bottiglieri T, Arning E, Tran NK, Ueland PM, Green R. Relationship of Cerebrospinal Fluid Vitamin B12 Status Markers With Parkinson's Disease Progression. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 32407590 DOI: 10.1002/mds.28073 |
0.573 |
|
| 2020 |
Kirby T, Walters DC, Brown M, Jansen E, Salomons GS, Turgeon C, Rinaldo P, Arning E, Ashcraft P, Bottiglieri T, Roullet JB, Gibson KM. Correction to: Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes. Metabolic Brain Disease. PMID 32306187 DOI: 10.1007/S11011-020-00569-4 |
0.563 |
|
| 2020 |
Kirby T, Walters DC, Brown M, Jansen E, Salomons GS, Turgeon C, Rinaldo P, Arning E, Ashcraft P, Bottiglieri T, Roullet JB, Gibson KM. Post-mortem tissue analyses in a patient with succinic semialdehyde dehydrogenase deficiency (SSADHD). I. Metabolomic outcomes. Metabolic Brain Disease. PMID 32172518 DOI: 10.1007/S11011-020-00550-1 |
0.607 |
|
| 2020 |
Singhal NK, Sternbach S, Fleming S, Alkhayer K, Shelestak J, Popescu D, Weaver A, Clements R, Wasek B, Bottiglieri T, Freeman EJ, McDonough J. Betaine restores epigenetic control and supports neuronal mitochondria in the cuprizone mouse model of multiple sclerosis. Epigenetics. PMID 32096676 DOI: 10.1080/15592294.2020.1735075 |
0.699 |
|
| 2020 |
Tondo M, Wasek B, Escola-Gil JC, Gonzalo-Calvo Dd, Harmon C, Arning E, Bottiglieri T. Altered Brain Metabolome Is Associated with Memory Impairment in the rTg4510 Mouse Model of Tauopathy. Metabolites. 10: 69. PMID 32075035 DOI: 10.3390/Metabo10020069 |
0.782 |
|
| 2020 |
Gu SX, Sonkar VK, Katare PB, Kumar R, Kruger WD, Arning E, Bottiglieri T, Lentz SR, Dayal S. Memantine Protects From Exacerbation of Ischemic Stroke and Blood Brain Barrier Disruption in Mild But Not Severe Hyperhomocysteinemia. Journal of the American Heart Association. 9: e013368. PMID 32067580 DOI: 10.1161/Jaha.119.013368 |
0.648 |
|
| 2020 |
Mosnier H, Kelly E, Lawrence K, Cruickshank S, Stacey S, McCall A, Dhatt S, Arning E, Bottiglieri T, Jadavji N. The Role of One-Carbon Metabolism After Ischemic Stroke in an Aged Mouse Model Current Developments in Nutrition. 4: 1226-1226. DOI: 10.1093/cdn/nzaa057_042 |
0.633 |
|
| 2019 |
Jadavji NM, Mosnier H, Kelly E, Lawrence K, Cruickshank S, Stacey S, McCall A, Dhatt S, Arning E, Bottiglieri T, Smith PD. One-carbon metabolism supplementation improves outcome after stroke in aged male MTHFR-deficient mice. Neurobiology of Disease. 104613. PMID 31525435 DOI: 10.1016/J.Nbd.2019.104613 |
0.751 |
|
| 2019 |
Brown M, Ashcraft P, Arning E, Bottiglieri T, Roullet JB, Gibson KM. Gamma-Hydroxybutyrate content in dried bloodspots facilitates newborn detection of succinic semialdehyde dehydrogenase deficiency. Molecular Genetics and Metabolism. PMID 31345667 DOI: 10.1016/j.ymgme.2019.07.010 |
0.601 |
|
| 2019 |
Abu Ahmad N, Raizman M, Weizmann N, Wasek B, Arning E, Bottiglieri T, Tirosh O, Troen AM. Betaine attenuates pathology by stimulating lipid oxidation in liver and regulating phospholipid metabolism in brain of methionine-choline-deficient rats. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201802683R. PMID 31120771 DOI: 10.1096/Fj.201802683R |
0.788 |
|
| 2019 |
Brown MN, Walters DC, Schmidt MA, Hill J, McConnell A, Jansen E, Salomons GS, Arning E, Bottiglieri T, Gibson KM, Roullet JB. Maternal Glutamine Supplementation in Murine Succinic Semialdehyde Dehydrogenase Deficiency (SSADHD), a Disorder of GABA Metabolism. Journal of Inherited Metabolic Disease. PMID 31032972 DOI: 10.1002/jimd.12107 |
0.62 |
|
| 2019 |
Brown M, Ashcraft P, Arning E, Bottiglieri T, McClintock W, Giancola F, Lieberman D, Hauser NS, Miller R, Roullet JB, Pearl P, Gibson KM. Rett syndrome (MECP2) and succinic semialdehyde dehydrogenase (ALDH5A1) deficiency in a developmentally delayed female. Molecular Genetics & Genomic Medicine. e629. PMID 30829465 DOI: 10.1002/Mgg3.629 |
0.556 |
|
| 2019 |
Walters DC, Arning E, Bottiglieri T, Jansen EEW, Salomons GS, Brown MN, Schmidt MA, Ainslie GR, Roullet JB, Gibson KM. Metabolomic analyses of vigabatrin (VGB)-Treated mice: GABA-transaminase inhibition significantly alters amino acid profiles in murine neural and non-neural tissues. Neurochemistry International. PMID 30822440 DOI: 10.1016/j.neuint.2019.02.015 |
0.577 |
|
| 2019 |
Czysz AH, South C, Gadad BS, Arning E, Soyombo A, Bottiglieri T, Trivedi MH. Can targeted metabolomics predict depression recovery? Results from the CO-MED trial. Translational Psychiatry. 9: 11. PMID 30664617 DOI: 10.1038/s41398-018-0349-6 |
0.55 |
|
| 2018 |
Arora K, Sequeira JM, Alarcon JM, Wasek B, Arning E, Bottiglieri T, Quadros EV. Neuropathology of vitamin B deficiency in the Cd320 mouse. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. fj201800754RR. PMID 30303736 DOI: 10.1096/Fj.201800754Rr |
0.778 |
|
| 2018 |
Dheda K, Lenders L, Magombedze G, Srivastava S, Raj P, Arning E, Ashcraft P, Bottiglieri T, Wainwright H, Pennel T, Linegar A, Moodley L, Pooran A, Pasipanodya JG, Sirgel FA, et al. Drug Penetration Gradients Associated with Acquired Drug Resistance in Tuberculosis Patients. American Journal of Respiratory and Critical Care Medicine. PMID 29877726 DOI: 10.1164/Rccm.201711-2333Oc |
0.557 |
|
| 2018 |
Hoffman A, Taleski G, Qian H, Wasek B, Arning E, Bottiglieri T, Sontag JM, Sontag E. Methylenetetrahydrofolate Reductase Deficiency Deregulates Regional Brain Amyloid-β Protein Precursor Expression and Phosphorylation Levels. Journal of Alzheimer's Disease : Jad. 64: 223-237. PMID 29865064 DOI: 10.3233/Jad-180032 |
0.792 |
|
| 2018 |
Wasek B, Arning E, Bottiglieri T. The use of microwave irradiation for quantitative analysis of neurotransmitters in the mouse brain. Journal of Neuroscience Methods. 307: 188-193. PMID 29802857 DOI: 10.1016/J.Jneumeth.2018.05.016 |
0.785 |
|
| 2018 |
Christensen KE, Bahous RH, Hou W, Deng L, Malysheva OV, Arning E, Bottiglieri T, Caudill MA, Jerome-Majewska LA, Rozen R. Low Dietary Folate Interacts with MTHFD1 Synthetase Deficiency in Mice, a Model for the R653Q Variant, to Increase Incidence of Developmental Delays and Defects. The Journal of Nutrition. 148: 501-509. PMID 29659962 DOI: 10.1093/Jn/Nxy013 |
0.618 |
|
| 2018 |
McKenna Iii J, Kapfhamer D, Kinchen JM, Wasek B, Dunworth M, Murray-Stewart T, Bottiglieri T, Casero RA, Gambello MJ. Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex. Human Molecular Genetics. PMID 29635516 DOI: 10.1093/Hmg/Ddy118 |
0.713 |
|
| 2018 |
Majtan T, Bublil EM, Park I, Arning E, Bottiglieri T, Glavin F, Kraus JP. Pharmacokinetics and pharmacodynamics of PEGylated truncated human cystathionine beta-synthase as treatment for homocystinuria. Life Sciences. PMID 29526799 DOI: 10.1016/j.lfs.2018.03.018 |
0.574 |
|
| 2018 |
Shiao SPK, Grayson J, Yu CH, Wasek B, Bottiglieri T. Gene Environment Interactions and Predictors of Colorectal Cancer in Family-Based, Multi-Ethnic Groups. Journal of Personalized Medicine. 8. PMID 29462916 DOI: 10.3390/Jpm8010010 |
0.657 |
|
| 2018 |
Gu SX, Sonkar V, Kumar R, Erland A, Bottiglieri T, Kruger W, Lentz S, Dayal S. Abstract WMP80: Cystathionine β Synthase Deficiency Exacerbates Cerebral Ischemia Reperfusion Injury Through Activation of the NMDA Receptor and Loss of Blood Brain Barrier Integrity in Mice Stroke. 49. DOI: 10.1161/Str.49.Suppl_1.Wmp80 |
0.368 |
|
| 2017 |
Meng XL, Arning E, Wight-Carter M, Day TS, Jabbarzadeh-Tabrizi S, Chen S, Ziegler RJ, Bottiglieri T, Schneider JW, Cheng SH, Schiffmann R, Shen JS. Priapism in a Fabry disease mouse model is associated with upregulated penile nNOS and eNOS expression. Journal of Inherited Metabolic Disease. PMID 29110178 DOI: 10.1007/S10545-017-0107-6 |
0.65 |
|
| 2017 |
Singhal NK, Freeman E, Arning E, Wasek B, Clements R, Sheppard C, Blake P, Bottiglieri T, McDonough J. Dysregulation of methionine metabolism in multiple sclerosis. Neurochemistry International. PMID 29080803 DOI: 10.1016/J.Neuint.2017.10.011 |
0.708 |
|
| 2017 |
Dayal S, Baumbach GL, Arning E, Bottiglieri T, Faraci FM, Lentz SR. Deficiency of superoxide dismutase promotes cerebral vascular hypertrophy and vascular dysfunction in hyperhomocysteinemia. Plos One. 12: e0175732. PMID 28414812 DOI: 10.1371/Journal.Pone.0175732 |
0.646 |
|
| 2017 |
Belik J, Shifrin Y, Arning E, Bottiglieri T, Pan J, Daigneault MC, Allen-Vercoe E. Corrigendum: Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice. Scientific Reports. 7: 44161. PMID 28398297 DOI: 10.1038/Srep44161 |
0.581 |
|
| 2017 |
Shen JS, Arning E, West ML, Day TS, Chen S, Meng XL, Forni S, McNeill N, Goker-Alpan O, Wang X, Ashcraft P, Moore DF, Cheng SH, Schiffmann R, Bottiglieri T. Tetrahydrobiopterin deficiency in the pathogenesis of Fabry disease. Human Molecular Genetics. PMID 28158561 DOI: 10.1093/Hmg/Ddx032 |
0.638 |
|
| 2017 |
Belik J, Shifrin Y, Arning E, Bottiglieri T, Pan J, Daigneault MC, Allen-Vercoe E. Intestinal microbiota as a tetrahydrobiopterin exogenous source in hph-1 mice. Scientific Reports. 7: 39854. PMID 28079055 DOI: 10.1038/Srep39854 |
0.623 |
|
| 2017 |
Shen J, Arning E, West ML, Day TS, Cheng SH, Schiffmann R, Bottiglieri T. Tetrahydrobiopterin deficiency in the pathogenesis of Fabry disease Molecular Genetics and Metabolism. 120. DOI: 10.1016/J.Ymgme.2016.11.319 |
0.604 |
|
| 2016 |
Vogel KR, Arning E, Bottiglieri T, Gibson KM. Multicompartment analysis of protein-restricted phenylketonuric mice reveals amino acid imbalances in brain. Journal of Inherited Metabolic Disease. PMID 27761676 DOI: 10.1007/S10545-016-9984-3 |
0.646 |
|
| 2016 |
Christensen KE, Hou W, Bahous RH, Deng L, Malysheva OV, Arning E, Bottiglieri T, Caudill MA, Jerome-Majewska LA, Rozen R. Moderate folic acid supplementation and MTHFD1-synthetase deficiency in mice, a model for the R653Q variant, result in embryonic defects and abnormal placental development. The American Journal of Clinical Nutrition. PMID 27707701 DOI: 10.3945/Ajcn.116.139519 |
0.642 |
|
| 2016 |
Wexler O, Gough MS, Morgan MA, Mack CM, Apostolakos MJ, Doolin KP, Mooney RA, Arning E, Bottiglieri T, Pietropaoli AP. Methionine Metabolites in Patients With Sepsis. Journal of Intensive Care Medicine. PMID 27591199 DOI: 10.1177/0885066616666002 |
0.623 |
|
| 2016 |
Arning E, Bottiglieri T. Erratum to: LC-MS/MS Analysis of Cerebrospinal Fluid Metabolites in the Pterin Biosynthetic Pathway. Jimd Reports. 29: 115. PMID 27272191 DOI: 10.1007/8904_2014_372 |
0.552 |
|
| 2016 |
Nicholls RE, Sontag JM, Zhang H, Staniszewski A, Yan S, Kim CY, Yim M, Woodruff CM, Arning E, Wasek B, Yin D, Bottiglieri T, Sontag E, Kandel ER, Arancio O. PP2A methylation controls sensitivity and resistance to β-amyloid-induced cognitive and electrophysiological impairments. Proceedings of the National Academy of Sciences of the United States of America. PMID 26951658 DOI: 10.1073/Pnas.1521018113 |
0.763 |
|
| 2016 |
Arning E, Bottiglieri T. Quantitation of S-Adenosylmethionine and S-Adenosylhomocysteine in Plasma Using Liquid Chromatography-Electrospray Tandem Mass Spectrometry Methods of Molecular Biology. 1378: 255-262. PMID 26602137 DOI: 10.1007/978-1-4939-3182-8_27 |
0.602 |
|
| 2016 |
Arning E, Bottiglieri T. Quantitation of 5-Methyltetrahydrofolate in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray Tandem Mass Spectrometry. Methods of Molecular Biology. 1378: 175-182. PMID 26602129 DOI: 10.1007/978-1-4939-3182-8_19 |
0.614 |
|
| 2016 |
Arning E, Bottiglieri T. Quantification of γ-Aminobutyric Acid in Cerebrospinal Fluid Using Liquid Chromatography-Electrospray Tandem Mass Spectrometry. Methods of Molecular Biology. 1378: 109-118. PMID 26602123 DOI: 10.1007/978-1-4939-3182-8_13 |
0.6 |
|
| 2016 |
Arning E, Bottiglieri T. LC-MS/MS Analysis of Cerebrospinal Fluid Metabolites in the Pterin Biosynthetic Pathway. Jimd Reports. 29: 1-9. PMID 25213568 DOI: 10.1007/8904_2014_336 |
0.579 |
|
| 2015 |
Singhal NK, Li S, Arning E, Alkhayer K, Clements R, Sarcyk Z, Dassanayake RS, Brasch NE, Freeman EJ, Bottiglieri T, McDonough J. Changes in Methionine Metabolism and Histone H3 Trimethylation Are Linked to Mitochondrial Defects in Multiple Sclerosis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 35: 15170-86. PMID 26558787 DOI: 10.1523/Jneurosci.4349-14.2015 |
0.628 |
|
| 2015 |
Vogel KR, Ainslie GR, Phillips B, Arning E, Bottiglieri T, Shen DD, Gibson KM. Physiological Competition of Brain Phenylalanine Accretion: Initial Pharmacokinetic Analyses of Aminoisobutyric and Methylaminoisobutyric Acids in Pah(enu2-/-) Mice. Molecular Genetics and Metabolism Reports. 3: 80-87. PMID 26120559 DOI: 10.1016/J.Ymgmr.2015.03.009 |
0.645 |
|
| 2015 |
Strauss KA, Ferreira C, Bottiglieri T, Zhao X, Arning E, Zhang S, Zeisel SH, Escolar ML, Presnick N, Puffenberger EG, Vugrek O, Kovacevic L, Wagner C, Mazariegos GV, Mudd SH, et al. Liver transplantation for treatment of severe S-adenosylhomocysteine hydrolase deficiency. Molecular Genetics and Metabolism. PMID 26095522 DOI: 10.1016/J.Ymgme.2015.06.005 |
0.619 |
|
| 2014 |
Dayal S, Blokhin IO, Erger RA, Jensen M, Arning E, Stevens JW, Bottiglieri T, Faraci FM, Lentz SR. Protective vascular and cardiac effects of inducible nitric oxide synthase in mice with hyperhomocysteinemia. Plos One. 9: e107734. PMID 25226386 DOI: 10.1371/Journal.Pone.0107734 |
0.607 |
|
| 2014 |
Sontag JM, Wasek B, Taleski G, Smith J, Arning E, Sontag E, Bottiglieri T. Altered protein phosphatase 2A methylation and Tau phosphorylation in the young and aged brain of methylenetetrahydrofolate reductase (MTHFR) deficient mice. Frontiers in Aging Neuroscience. 6: 214. PMID 25202269 DOI: 10.3389/fnagi.2014.00214 |
0.798 |
|
| 2014 |
Fang P, Zhang D, Cheng Z, Yan C, Jiang X, Kruger WD, Meng S, Arning E, Bottiglieri T, Choi ET, Han Y, Yang XF, Wang H. Hyperhomocysteinemia potentiates hyperglycemia-induced inflammatory monocyte differentiation and atherosclerosis. Diabetes. 63: 4275-90. PMID 25008174 DOI: 10.2337/Db14-0809 |
0.641 |
|
| 2014 |
Vogel KR, Arning E, Wasek BL, McPherson S, Bottiglieri T, Gibson KM. Brain-blood amino acid correlates following protein restriction in murine maple syrup urine disease. Orphanet Journal of Rare Diseases. 9: 73. PMID 24886632 DOI: 10.1186/1750-1172-9-73 |
0.777 |
|
| 2014 |
Harding CO, Winn SR, Gibson KM, Arning E, Bottiglieri T, Grompe M. Pharmacologic inhibition of L-tyrosine degradation ameliorates cerebral dopamine deficiency in murine phenylketonuria (PKU). Journal of Inherited Metabolic Disease. 37: 735-43. PMID 24487571 DOI: 10.1007/S10545-013-9675-2 |
0.621 |
|
| 2014 |
Yano S, Moseley K, Bottiglieri T, Arning E, Azen C. Maternal Phenylketonuria International Collaborative Study revisited: evaluation of maternal nutritional risk factors besides phenylalanine for fetal congenital heart defects Journal of Inherited Metabolic Disease. 37: 39-42. PMID 23784316 DOI: 10.1007/S10545-013-9627-X |
0.615 |
|
| 2014 |
Arning E, Shen J, LeMoine K, Schiffmann R, West M, Bottiglieri T. Tetrahydrobiopterin in Fabry disease Molecular Genetics and Metabolism. 111. DOI: 10.1016/J.Ymgme.2013.12.027 |
0.535 |
|
| 2013 |
Vogel KR, Arning E, Wasek BL, Bottiglieri T, Gibson KM. Characterization of 2-(methylamino)alkanoic acid capacity to restrict blood-brain phenylalanine transport in Pah enu2 mice: preliminary findings. Molecular Genetics and Metabolism. 110: S71-8. PMID 23999161 DOI: 10.1016/J.Ymgme.2013.08.004 |
0.788 |
|
| 2013 |
Inoue-Choi M, Nelson HH, Robien K, Arning E, Bottiglieri T, Koh WP, Yuan JM. Plasma S-adenosylmethionine, DNMT polymorphisms, and peripheral blood LINE-1 methylation among healthy Chinese adults in Singapore. Bmc Cancer. 13: 389. PMID 23957506 DOI: 10.1186/1471-2407-13-389 |
0.596 |
|
| 2013 |
Butler LM, Arning E, Wang R, Bottiglieri T, Govindarajan S, Gao YT, Yuan JM. Prediagnostic levels of serum one-carbon metabolites and risk of hepatocellular carcinoma. Cancer Epidemiology, Biomarkers & Prevention : a Publication of the American Association For Cancer Research, Cosponsored by the American Society of Preventive Oncology. 22: 1884-93. PMID 23897582 DOI: 10.1158/1055-9965.Epi-13-0497 |
0.602 |
|
| 2013 |
Christensen KE, Deng L, Leung KY, Arning E, Bottiglieri T, Malysheva OV, Caudill MA, Krupenko NI, Greene ND, Jerome-Majewska L, MacKenzie RE, Rozen R. A novel mouse model for genetic variation in 10-formyltetrahydrofolate synthetase exhibits disturbed purine synthesis with impacts on pregnancy and embryonic development Human Molecular Genetics. 22: 3705-3719. PMID 23704330 DOI: 10.1093/Hmg/Ddt223 |
0.628 |
|
| 2013 |
Skvorak KJ, Dorko K, Marongiu F, Tahan V, Hansel MC, Gramignoli R, Arning E, Bottiglieri T, Gibson KM, Strom SC. Improved amino acid, bioenergetic metabolite and neurotransmitter profiles following human amnion epithelial cell transplant in intermediate maple syrup urine disease mice. Molecular Genetics and Metabolism. 109: 132-8. PMID 23566440 DOI: 10.1016/J.Ymgme.2013.02.011 |
0.635 |
|
| 2013 |
Bottiglieri T. Folate, Vitamin B12, and S-Adenosylmethionine Psychiatric Clinics of North America. 36: 1-13. PMID 23538072 DOI: 10.1016/J.Psc.2012.12.001 |
0.31 |
|
| 2013 |
Lai SC, Nakayama Y, Sequeira JM, Wlodarczyk BJ, Cabrera RM, Finnell RH, Bottiglieri T, Quadros EV. The transcobalamin receptor knockout mouse: a model for vitamin B12 deficiency in the central nervous system. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 2468-75. PMID 23430977 DOI: 10.1096/Fj.12-219055 |
0.358 |
|
| 2013 |
Glier MB, Ngai YF, Sulistyoningrum DC, Aleliunas RE, Bottiglieri T, Devlin AM. Tissue-specific relationship of S-adenosylhomocysteine with allele-specific H19/Igf2 methylation and imprinting in mice with hyperhomocysteinemia Epigenetics. 8: 44-53. PMID 23221482 DOI: 10.4161/Epi.23063 |
0.344 |
|
| 2013 |
Vogel KR, Arning E, Wasek BL, Bottiglieri T, Gibson KM. Non-physiological amino acid (NPAA) therapy targeting brain phenylalanine reduction: pilot studies in PAHENU2 mice. Journal of Inherited Metabolic Disease. 36: 513-23. PMID 22976763 DOI: 10.1007/S10545-012-9524-8 |
0.784 |
|
| 2012 |
Bottiglieri T, Arning E, Wasek B, Nunbhakdi-Craig V, Sontag J, Sontag E. Acute administration of L-DOPA induces changes in methylation metabolites, reduced protein phosphatase 2A methylation, and hyperphosphorylation of Tau protein in mouse brain. The Journal of Neuroscience. 32: 9173-9181. PMID 22764226 DOI: 10.1523/Jneurosci.0125-12.2012 |
0.788 |
|
| 2012 |
Inoue-Choi M, Nelson HH, Robien K, Arning E, Bottiglieri T, Koh WP, Yuan JM. One-carbon metabolism nutrient status and plasma S-adenosylmethionine concentrations in middle-aged and older Chinese in Singapore. International Journal of Molecular Epidemiology and Genetics. 3: 160-73. PMID 22724053 |
0.59 |
|
| 2012 |
Mischoulon D, Alpert JE, Arning E, Bottiglieri T, Fava M, Papakostas GI. Bioavailability of S-adenosyl methionine and impact on response in a randomized, double-blind, placebo-controlled trial in major depressive disorder. The Journal of Clinical Psychiatry. 73: 843-8. PMID 22687580 DOI: 10.4088/Jcp.11M07139 |
0.617 |
|
| 2012 |
Marin-Valencia I, Good LB, Ma Q, Duarte J, Bottiglieri T, Sinton CM, Heilig CW, Pascual JM. Glut1 deficiency (G1D): epilepsy and metabolic dysfunction in a mouse model of the most common human phenotype. Neurobiology of Disease. 48: 92-101. PMID 22683290 DOI: 10.1016/J.Nbd.2012.04.011 |
0.368 |
|
| 2012 |
Inoue-Choi M, Nelson HH, Robien K, Arning E, Bottiglieri T, Koh W, Yuan J. Abstract 1038: PlasmaS-adenosylmethionine levels, genetic polymorphisms ofDNMT1andDNMT3A, and LINE-1 DNA methylation among Chinese in Singapore Cancer Research. 72: 1038-1038. DOI: 10.1158/1538-7445.Am2012-1038 |
0.601 |
|
| 2011 |
Gough MS, Morgan MA, Mack CM, Darling DC, Frasier LM, Doolin KP, Apostolakos MJ, Stewart JC, Graves BT, Arning E, Bottiglieri T, Mooney RA, Frampton MW, Pietropaoli AP. The ratio of arginine to dimethylarginines is reduced and predicts outcomes in patients with severe sepsis. Critical Care Medicine. 39: 1351-8. PMID 21378552 DOI: 10.1097/Ccm.0B013E318212097C |
0.602 |
|
| 2010 |
Rodionov RN, Dayoub H, Lynch CM, Wilson KM, Stevens JW, Murry DJ, Kimoto M, Arning E, Bottiglieri T, Cooke JP, Baumbach GL, Faraci FM, Lentz SR. Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. Circulation Research. 106: 551-8. PMID 20019334 DOI: 10.1161/Circresaha.109.200360 |
0.641 |
|
| 2010 |
Devlin AM, Singh R, Bottiglieri T, Innis SM, Green TJ. Hepatic acyl-coenzyme A:cholesterol acyltransferase-2 expression is decreased in mice with hyperhomocysteinemia Journal of Nutrition. 140: 231-237. PMID 20018805 DOI: 10.3945/Jn.109.112920 |
0.387 |
|
| 2009 |
Roe CR, Bottiglieri T, Wallace M, Arning E, Martin A. Adult Polyglucosan Body Disease (APBD): Anaplerotic diet therapy (Triheptanoin) and demonstration of defective methylation pathways Molecular Genetics and Metabolism. 101: 246-252. PMID 20655781 DOI: 10.1016/J.Ymgme.2010.06.017 |
0.639 |
|
| 2009 |
Skvorak KJ, Hager EJ, Arning E, Bottiglieri T, Paul HS, Strom SC, Homanics GE, Sun Q, Jansen EE, Jakobs C, Zinnanti WJ, Gibson KM. Hepatocyte transplantation (HTx) corrects selected neurometabolic abnormalities in murine intermediate maple syrup urine disease (iMSUD). Biochimica Et Biophysica Acta. 1792: 1004-10. PMID 19699299 DOI: 10.1016/J.Bbadis.2009.08.006 |
0.638 |
|
| 2009 |
Li S, Arning E, Liu C, Vitvitsky V, Hernandez C, Banerjee R, Bottiglieri T, Lin JD. Regulation of homocysteine homeostasis through the transcriptional coactivator PGC-1alpha. American Journal of Physiology. Endocrinology and Metabolism. 296: E543-8. PMID 19158324 DOI: 10.1152/Ajpendo.90719.2008 |
0.626 |
|
| 2009 |
Bottiglieri T. Folate, Vitamin B12, and Neuropsychiatric Disorders Nutrition Reviews. 54: 382-390. PMID 9155210 DOI: 10.1111/J.1753-4887.1996.Tb03851.X |
0.339 |
|
| 2009 |
Roe C, Arning E, Bottiglieri T, Reuser A. 117. IGF-1 resistance is a reversible feature of late-onset acid maltase deficiency (AMD) Molecular Genetics and Metabolism. 96. DOI: 10.1016/J.Ymgme.2008.11.118 |
0.592 |
|
| 2008 |
Sontag JM, Nunbhakdi-Craig V, Montgomery L, Arning E, Bottiglieri T, Sontag E. Folate deficiency induces in vitro and mouse brain region-specific downregulation of leucine carboxyl methyltransferase-1 and protein phosphatase 2A B(alpha) subunit expression that correlate with enhanced tau phosphorylation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 11477-87. PMID 18987184 DOI: 10.1523/Jneurosci.2816-08.2008 |
0.636 |
|
| 2008 |
Aisen PS, Schneider LS, Sano M, Diaz-Arrastia R, van Dyck CH, Weiner MF, Bottiglieri T, Jin S, Stokes KT, Thomas RG, Thal LJ. High-dose B vitamin supplementation and cognitive decline in Alzheimer disease: a randomized controlled trial. Jama. 300: 1774-83. PMID 18854539 DOI: 10.1001/Jama.300.15.1774 |
0.304 |
|
| 2008 |
Dayal S, Rodionov RN, Arning E, Bottiglieri T, Kimoto M, Murry DJ, Cooke JP, Faraci FM, Lentz SR. Tissue-specific downregulation of dimethylarginine dimethylaminohydrolase in hyperhomocysteinemia American Journal of Physiology - Heart and Circulatory Physiology. 295: H816-H825. PMID 18567702 DOI: 10.1152/Ajpheart.01348.2007 |
0.584 |
|
| 2008 |
Locascio JJ, Fukumoto H, Yap L, Bottiglieri T, Growdon JH, Hyman BT, Irizarry MC. Plasma amyloid beta-protein and C-reactive protein in relation to the rate of progression of Alzheimer disease. Archives of Neurology. 65: 776-85. PMID 18541797 DOI: 10.1001/Archneur.65.6.776 |
0.31 |
|
| 2008 |
Dayoub H, Rodionov R, Lynch C, Cooke JP, Arning E, Bottiglieri T, Lentz SR, Faraci FM. Overexpression of dimethylarginine dimethylaminohydrolase inhibits asymmetric dimethylarginine-induced endothelial dysfunction in the cerebral circulation Stroke. 39: 180-184. PMID 18063827 DOI: 10.1161/Strokeaha.107.490631 |
0.645 |
|
| 2007 |
Knerr I, Pearl PL, Bottiglieri T, Snead OC, Jakobs C, Gibson KM. Therapeutic concepts in succinate semialdehyde dehydrogenase (SSADH; ALDH5a1) deficiency (gamma-hydroxybutyric aciduria). Hypotheses evolved from 25 years of patient evaluation, studies in Aldh5a1-/- mice and characterization of gamma-hydroxybutyric acid pharmacology. Journal of Inherited Metabolic Disease. 30: 279-94. PMID 17457693 DOI: 10.1007/S10545-007-0574-2 |
0.356 |
|
| 2007 |
Elmore CL, Wu X, Leclerc D, Watson ED, Bottiglieri T, Krupenko NI, Krupenko SA, Cross JC, Rozen R, Gravel RA, Matthews RG. Metabolic derangement of methionine and folate metabolism in mice deficient in methionine synthase reductase. Molecular Genetics and Metabolism. 91: 85-97. PMID 17369066 DOI: 10.1016/J.Ymgme.2007.02.001 |
0.385 |
|
| 2007 |
Sontag E, Nunbhakdi-Craig V, Sontag JM, Diaz-Arrastia R, Ogris E, Dayal S, Lentz SR, Arning E, Bottiglieri T. Protein phosphatase 2A methyltransferase links homocysteine metabolism with tau and amyloid precursor protein regulation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 2751-9. PMID 17360897 DOI: 10.1523/Jneurosci.3316-06.2007 |
0.636 |
|
| 2007 |
Wilson KM, McCaw RB, Leo L, Arning E, Lhoták S, Bottiglieri T, Austin RC, Lentz SR. Prothrombotic effects of hyperhomocysteinemia and hypercholesterolemia in ApoE-deficient mice. Arteriosclerosis, Thrombosis, and Vascular Biology. 27: 233-40. PMID 17082485 DOI: 10.1161/01.Atv.0000251607.96118.Af |
0.637 |
|
| 2006 |
Dayal S, Wilson KM, Leo L, Arning E, Bottiglieri T, Lentz SR. Enhanced susceptibility to arterial thrombosis in a murine model of hyperhomocysteinemia. Blood. 108: 2237-43. PMID 16804115 DOI: 10.1182/Blood-2006-02-005991 |
0.633 |
|
| 2005 |
Irizarry MC, Gurol ME, Raju S, Diaz-Arrastia R, Locascio JJ, Tennis M, Hyman BT, Growdon JH, Greenberg SM, Bottiglieri T. Association of homocysteine with plasma amyloid beta protein in aging and neurodegenerative disease. Neurology. 65: 1402-8. PMID 16275827 DOI: 10.1212/01.Wnl.0000183063.99107.5C |
0.3 |
|
| 2005 |
Dayal S, Devlin AM, McCaw RB, Liu ML, Arning E, Bottiglieri T, Shane B, Faraci FM, Lentz SR. Cerebral vascular dysfunction in methionine synthase-deficient mice Circulation. 112: 737-744. PMID 16043641 DOI: 10.1161/CIRCULATIONAHA.104.529248 |
0.601 |
|
| 2005 |
Bodamer OA, Sahoo T, Beaudet AL, O'Brien WE, Bottiglieri T, Stöckler-Ipsiroglu S, Wagner C, Scaglia F. Creatine metabolism in combined methylmalonic aciduria and homocystinuria. Annals of Neurology. 57: 557-60. PMID 15786446 DOI: 10.1002/Ana.20419 |
0.345 |
|
| 2005 |
Moretti P, Sahoo T, Hyland K, Bottiglieri T, Peters S, del Gaudio D, Roa B, Curry S, Zhu H, Finnell RH, Neul JL, Ramaekers VT, Blau N, Bacino CA, Miller G, et al. Cerebral folate deficiency with developmental delay, autism, and response to folinic acid. Neurology. 64: 1088-90. PMID 15781839 DOI: 10.1212/01.Wnl.0000154641.08211.B7 |
0.321 |
|
| 2004 |
Duncan GE, Perri MG, Anton SD, Limacher MC, Martin AD, Lowenthal DT, Arning E, Bottiglieri T, Stacpoole PW. Effects of exercise on emerging and traditional cardiovascular risk factors. Preventive Medicine. 39: 894-902. PMID 15475021 DOI: 10.1016/J.Ypmed.2004.03.012 |
0.582 |
|
| 2004 |
O'Suilleabhain PE, Bottiglieri T, Dewey RB, Sharma S, Diaz-Arrastia R. Modest increase in plasma homocysteine follows levodopa initiation in Parkinson's disease Movement Disorders. 19: 1403-1408. PMID 15390053 DOI: 10.1002/Mds.20253 |
0.305 |
|
| 2004 |
Goff DC, Bottiglieri T, Arning E, Shih V, Freudenreich O, Evins AE, Henderson DC, Baer L, Coyle J. Folate, homocysteine, and negative symptoms in schizophrenia American Journal of Psychiatry. 161: 1705-1708. PMID 15337665 DOI: 10.1176/Appi.Ajp.161.9.1705 |
0.603 |
|
| 2004 |
Dayal S, Arning E, Bottiglieri T, Böger RH, Sigmund CD, Faraci FM, Lentz SR. Cerebral vascular dysfunction mediated by superoxide in hyperhomocysteinemic mice. Stroke; a Journal of Cerebral Circulation. 35: 1957-62. PMID 15178827 DOI: 10.1161/01.Str.0000131749.81508.18 |
0.619 |
|
| 2004 |
Quinn CT, Griener JC, Bottiglieri T, Arning E, Winick NJ. Effects of intraventricular methotrexate on folate, adenosine, and homocysteine metabolism in cerebrospinal fluid. Journal of Pediatric Hematology/Oncology. 26: 386-8. PMID 15167354 DOI: 10.1097/00043426-200406000-00011 |
0.636 |
|
| 2004 |
Devlin AM, Arning E, Bottiglieri T, Faraci FM, Rozen R, Lentz SR. Effect of Mthfr genotype on diet-induced hyperhomocysteinemia and vascular function in mice Blood. 103: 2624-2629. PMID 14630804 DOI: 10.1182/Blood-2003-09-3078 |
0.656 |
|
| 2003 |
Gupta M, Hogema BM, Grompe M, Bottiglieri TG, Concas A, Biggio G, Sogliano C, Rigamonti AE, Pearl PL, Snead OC, Jakobs C, Gibson KM. Murine succinate semialdehyde dehydrogenase deficiency. Annals of Neurology. 54: S81-90. PMID 12891658 DOI: 10.1002/Ana.10625 |
0.321 |
|
| 2003 |
Harding CO, Pillers DA, Steiner RD, Bottiglieri T, Rosenblatt DS, Debley J, Michael Gibson K. Potential for misdiagnosis due to lack of metabolic derangement in combined methylmalonic aciduria/hyperhomocysteinemia (cblC) in the neonate. Journal of Perinatology : Official Journal of the California Perinatal Association. 23: 384-6. PMID 12847533 DOI: 10.1038/Sj.Jp.7210955 |
0.311 |
|
| 2002 |
Dayal S, Brown KL, Weydert CJ, Oberley LW, Arning E, Bottiglieri T, Faraci FM, Lentz SR. Deficiency of glutathione peroxidase-1 sensitizes hyperhomocysteinemic mice to endothelial dysfunction. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1996-2002. PMID 12482825 DOI: 10.1161/01.Atv.0000041629.92741.Dc |
0.648 |
|
| 2002 |
Baumbach GL, Sigmund CD, Bottiglieri T, Lentz SR. Structure of cerebral arterioles in cystathionine beta-synthase-deficient mice. Circulation Research. 91: 931-7. PMID 12433838 DOI: 10.1161/01.Res.0000041408.64867.1D |
0.372 |
|
| 2002 |
Tran P, Hiou-Tim F, Frosst P, Lussier-Cacan S, Bagley P, Selhub J, Bottiglieri T, Rozen R. The curly-tail (ct) mouse, an animal model of neural tube defects, displays altered homocysteine metabolism without folate responsiveness or a defect in Mthfr. Molecular Genetics and Metabolism. 76: 297-304. PMID 12208134 DOI: 10.1016/S1096-7192(02)00108-7 |
0.334 |
|
| 2002 |
Lentz SR, Piegors DJ, Fernández JA, Erger RA, Arning E, René Malinow M, Griffin JH, Bottiglieri T, Haynes WG, Heistad DD. Effect of hyperhomocysteinemia on protein C activation and activity Blood. 100: 2108-2112. PMID 12200374 DOI: 10.1182/Blood-2002-03-0727 |
0.628 |
|
| 2002 |
Gibson KM, Schor DSM, Gupta M, Guerand WS, Senephansiri H, Burlingame TG, Bartels H, Hogema BM, Bottiglieri T, Froestl W, Snead OC, Grompe M, Jakobs C. Focal neurometabolic alterations in mice deficient for succinate semialdehyde dehydrogenase Journal of Neurochemistry. 81: 71-79. PMID 12067239 DOI: 10.1046/J.1471-4159.2002.00784.X |
0.393 |
|
| 2002 |
Di Rocco A, Bottiglieri T, Werner P, Geraci A, Simpson D, Godbold J, Morgello S. Abnormal cobalamin-dependent transmethylation in AIDS-associated myelopathy. Neurology. 58: 730-5. PMID 11889235 DOI: 10.1212/Wnl.58.5.730 |
0.32 |
|
| 2001 |
Bottiglieri T, Parnetti L, Arning E, Ortiz T, Amici S, Lanari A, Gallai V. Plasma total homocysteine levels and the C677T mutation in the methylenetetrahydrofolate reductase (MTHFR) gene: a study in an Italian population with dementia. Mechanisms of Ageing and Development. 122: 2013-2023. PMID 11589919 DOI: 10.1016/S0047-6374(01)00307-4 |
0.621 |
|
| 2001 |
Hogema BM, Gupta M, Senephansiri H, Burlingame TG, Taylor M, Jakobs C, Schutgens RBH, Froestl W, Snead OC, Diaz-Arrastia R, Bottiglieri T, Grompe M, Gibson KM. Pharmacologic rescue of lethal seizures in mice deficient in succinate semialdehyde dehydrogenase Nature Genetics. 29: 212-216. PMID 11544478 DOI: 10.1038/Ng727 |
0.355 |
|
| 2001 |
Dayal S, Bottiglieri T, Arning E, Maeda N, Malinow MR, Sigmund CD, Heistad DD, Faraci FM, Lentz SR. Endothelial dysfunction and elevation of S-adenosylhomocysteine in cystathionine beta-synthase-deficient mice. Circulation Research. 88: 1203-9. PMID 11397788 DOI: 10.1161/Hh1101.092180 |
0.399 |
|
| 2001 |
Chen Z, Karaplis AC, Ackerman SL, Pogribny IP, Melnyk S, Lussier-Cacan S, Chen MF, Pai A, John SW, Smith RS, Bottiglieri T, Bagley P, Selhub J, Rudnicki MA, James SJ, et al. Mice deficient in methylenetetrahydrofolate reductase exhibit hyperhomocysteinemia and decreased methylation capacity, with neuropathology and aortic lipid deposition. Human Molecular Genetics. 10: 433-43. PMID 11181567 DOI: 10.1093/Hmg/10.5.433 |
0.393 |
|
| 2000 |
Bottiglieri T, Laundy M, Crellin R, Toone BK, Carney MW, Reynolds EH. Homocysteine, folate, methylation, and monoamine metabolism in depression. Journal of Neurology, Neurosurgery, and Psychiatry. 69: 228-32. PMID 10896698 DOI: 10.1136/Jnnp.69.2.228 |
0.339 |
|
| 2000 |
Gibson KM, Steine RD, Grompe M, Burlingame T, Senephansiri H, Bottiglieri T, Debley J, Campbell P. Potential for clinical misdiagnosis of combined methylmalonic aciduria/homocysteinemia (MMA/HCYS) due to absence of acute metabolic derangement Genetics in Medicine. 2: 61-62. DOI: 10.1097/00125817-200001000-00048 |
0.34 |
|
| 1998 |
Gibson KM, Hoffmann GF, Hodson AK, Bottiglieri T, Jakobs C. 4-hydroxybutyric acid and the clinical phenotype of succinic semialdehyde dehydrogenase deficiency, an inborn error of GABA metabolism Neuropediatrics. 29: 14-22. PMID 9553943 DOI: 10.1055/S-2007-973527 |
0.332 |
|
| 1997 |
Bottiglieri T. Ademetionine (S-adenosylmethionine) neuropharmacology: implications for drug therapies in psychiatric and neurological disorders. Expert Opinion On Investigational Drugs. 6: 417-426. PMID 15989609 DOI: 10.1517/13543784.6.4.417 |
0.342 |
|
| 1997 |
Quinn CT, Griener JC, Bottiglieri T, Hyland K, Farrow A, Kamen BA. Elevation of homocysteine and excitatory amino acid neurotransmitters in the CSF of children who receive methotrexate for the treatment of cancer. Journal of Clinical Oncology. 15: 2800-2806. PMID 9256122 DOI: 10.1200/Jco.1997.15.8.2800 |
0.328 |
|
| 1994 |
Bottiglieri T, Hyland K, Reynolds EH. The Clinical Potential of Ademetionine (S-Adenosylmethionine) in Neurological Disorders Drugs. 48: 137-152. PMID 7527320 DOI: 10.2165/00003495-199448020-00002 |
0.363 |
|
| 1993 |
Reynolds EH, Bottiglieri T, Laundy M, Stern J, Payan J, Linnell J, Faludy J. Subacute combined degeneration with high serum vitamin B12 level and abnormal vitamin B12 binding protein. New cause of an old syndrome. Archives of Neurology. 50: 739-42. PMID 8323478 DOI: 10.1001/Archneur.1993.00540070055015 |
0.307 |
|
| 1992 |
Reynolds EH, Bottiglieri T, Laundy M, Crellin RF, Kirker SG. Vitamin B12 metabolism in multiple sclerosis. Archives of Neurology. 49: 649-52. PMID 1596201 DOI: 10.1001/Archneur.1992.00530300089014 |
0.319 |
|
| 1990 |
Crellin RF, Bottiglieri T, Reynolds EH. Multiple sclerosis and macrocytosis Acta Neurologica Scandinavica. 81: 388-391. PMID 2375238 DOI: 10.1111/J.1600-0404.1990.Tb00981.X |
0.313 |
|
| 1988 |
Hyland K, Smith I, Bottiglieri T, Perry J, Wendel U, Clayton PT, Leonard JV. Demyelination and decreased S-adenosylmethionine in 5,10-methylenetetrahydrofolate reductase deficiency. Neurology. 38: 459-459. PMID 3347350 DOI: 10.1212/Wnl.38.3.459 |
0.334 |
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