Isin Cakir, Ph.D. - Publications

Affiliations: 
2010 Brown University, Providence, RI 
Area:
Molecular Biology

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Çakır I, Lining Pan P, Hadley CK, El-Gamal A, Fadel A, Elsayegh D, Mohamed O, Rizk NM, Ghamari-Langroudi M. Sulforaphane reduces obesity by reversing leptin resistance. Elife. 11. PMID 35323110 DOI: 10.7554/eLife.67368  0.498
2022 Çakır I, Hadley CK, Pan PL, Bagchi RA, Ghamari-Langroudi M, Porter DT, Wang Q, Litt MJ, Jana S, Hagen S, Lee P, White A, Lin JD, McKinsey TA, Cone RD. Histone deacetylase 6 inhibition restores leptin sensitivity and reduces obesity. Nature Metabolism. PMID 35039672 DOI: 10.1038/s42255-021-00515-3  0.478
2021 Yong Y, Cakir I, Lining Pan P, Biddinger JE, Bluett RJ, Mackie K, Bingham N, Patel S, Ghamari-Langroudi M. Endogenous cannabinoids are required for MC4R-mediated control of energy homeostasis. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34654741 DOI: 10.1073/pnas.2015990118  0.406
2021 Wang Q, Zhang P, Cakir I, Mi L, Cone RD, Lin JD. Deletion of the feeding-induced hepatokine TSK ameliorates the melanocortin obesity syndrome. Diabetes. PMID 34183373 DOI: 10.2337/db21-0161  0.45
2020 Hadley C, Cakir I, Cone RD. SAT-604 The Role of the Focal Adhesion Kinase Family in Leptin Receptor Signaling Journal of the Endocrine Society. 4. DOI: 10.1210/Jendso/Bvaa046.666  0.404
2019 Andreoli MF, Donato J, Cakir I, Perello M. Leptin resensitization: a reversion of leptin resistant states. The Journal of Endocrinology. PMID 30959481 DOI: 10.1530/Joe-18-0606  0.436
2019 Cakir I, Diaz Martinez M, Lining Pan P, Welch EB, Patel S, Ghamari-Langroudi M. Leptin Receptor Signaling in Sim1-expressing Neurons Regulates Body Temperature and Adaptive Thermogenesis. Endocrinology. PMID 30802281 DOI: 10.1210/en.2019-00062  0.39
2019 Cakir I, Nillni EA. Endoplasmic Reticulum Stress, the Hypothalamus, and Energy Balance. Trends in Endocrinology and Metabolism: Tem. PMID 30691778 DOI: 10.1016/J.Tem.2019.01.002  0.663
2018 Anderson EJP, Ghamari-Langroudi M, Cakir I, Litt MJ, Chen V, Reggiardo RE, Millhauser GL, Cone RD. Late onset obesity in mice with targeted deletion of potassium inward rectifier Kir7.1 from cells expressing the melanocortin-4 receptor. Journal of Neuroendocrinology. e12670. PMID 30561082 DOI: 10.1111/Jne.12670  0.419
2017 Litt MJ, Okoye GD, Lark D, Cakir I, Moore C, Barber MC, Atkinson J, Fessel J, Moslehi J, Cone RD. Loss of the melanocortin-4 receptor in mice causes dilated cardiomyopathy. Elife. 6. PMID 28829041 DOI: 10.7554/Elife.28118  0.473
2016 Anderson EJ, Cakir I, Carrington S, Cone R, Ghamari-Langroudi M, Gillyard T, Gimenez LE, Litt M. Regulation of feeding and energy homeostasis by α-MSH. Journal of Molecular Endocrinology. PMID 26939593 DOI: 10.1530/Jme-16-0014  0.452
2014 Park SW, Herrema H, Salazar M, Cakir I, Cabi S, Basibuyuk Sahin F, Chiu YH, Cantley LC, Ozcan U. BRD7 regulates XBP1s' activity and glucose homeostasis through its interaction with the regulatory subunits of PI3K. Cell Metabolism. 20: 73-84. PMID 24836559 DOI: 10.1016/J.Cmet.2014.04.006  0.306
2013 Cakir I, Cyr NE, Perello M, Litvinov BP, Romero A, Stuart RC, Nillni EA. Obesity induces hypothalamic endoplasmic reticulum stress and impairs proopiomelanocortin (POMC) post-translational processing. The Journal of Biological Chemistry. 288: 17675-88. PMID 23640886 DOI: 10.1074/Jbc.M113.475343  0.652
2011 Perello M, Çakir I, Cyr NE, Romero A, Stuart RC, Chiappini F, Hollenberg AN, Nillni EA. Maintenance of the thyroid access during diet-induced obesity in rodents is controlled at the central level (American Journal of Physiology - Endocrinology and Metabolism (2010) 299, DOI:10.1152/ajpendo.00448.2010) American Journal of Physiology - Endocrinology and Metabolism. 300: E422. DOI: 10.1152/Ajpendo.Zh1-6178-Corr.2011  0.632
2010 Perello M, Cakir I, Cyr NE, Romero A, Stuart RC, Chiappini F, Hollenberg AN, Nillni EA. Maintenance of the thyroid axis during diet-induced obesity in rodents is controlled at the central level. American Journal of Physiology. Endocrinology and Metabolism. 299: E976-89. PMID 20858755 DOI: 10.1152/Ajpendo.00448.2010  0.662
2009 Cakir I, Perello M, Lansari O, Messier NJ, Vaslet CA, Nillni EA. Hypothalamic Sirt1 regulates food intake in a rodent model system. Plos One. 4: e8322. PMID 20020036 DOI: 10.1371/Journal.Pone.0008322  0.624
2008 Romero A, Cakir I, Vaslet CA, Stuart RC, Lansari O, Lucero HA, Nillni EA. Role of a pro-sequence in the secretory pathway of prothyrotropin-releasing hormone. The Journal of Biological Chemistry. 283: 31438-48. PMID 18779326 DOI: 10.1074/Jbc.M803413200  0.566
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