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Edward A. Lemke - Publications

Affiliations: 
EMBL Heidelberg 
Area:
biophysics, chemical biology
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110 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Werther P, Yserentant K, Braun F, Grußmayer K, Navikas V, Yu M, Zhang Z, Ziegler MJ, Mayer C, Gralak AJ, Busch M, Chi W, Rominger F, Radenovic A, Liu X, ... Lemke EA, et al. Bio-orthogonal Red and Far-Red Fluorogenic Probes for Wash-Free Live-Cell and Super-resolution Microscopy. Acs Central Science. 7: 1561-1571. PMID 34584958 DOI: 10.1021/acscentsci.1c00703  0.303
2021 Paci G, Caria J, Lemke EA. Cargo transport through the nuclear pore complex at a glance. Journal of Cell Science. 134. PMID 34432038 DOI: 10.1242/jcs.247874  0.708
2021 Lerner E, Barth A, Hendrix J, Ambrose B, Birkedal V, Blanchard SC, Börner R, Sung Jung H, Cordes T, Craggs TD, Deniz AA, Diao J, Fei J, Gonzalez RL, Gopich IV, ... ... Lemke EA, et al. FRET-based dynamic structural biology: Challenges, perspectives and an appeal for open-science practices. Elife. 10. PMID 33779550 DOI: 10.7554/eLife.60416  0.712
2021 Paci G, Caria J, Lemke EA. Cargo transport through the nuclear pore complex at a glance. Journal of Cell Science. 134. PMID 33495357 DOI: 10.1242/jcs.247874  0.708
2020 Paci G, Zheng T, Caria J, Zilman A, Lemke EA. Molecular determinants of large cargo transport into the nucleus. Elife. 9. PMID 32692309 DOI: 10.7554/Elife.55963  0.734
2020 Koehler C, Estrada Girona G, Reinkemeier CD, Lemke EA. Inducible Genetic Code Expansion in Eukaryotes. Chembiochem : a European Journal of Chemical Biology. PMID 32598534 DOI: 10.1002/Cbic.202000338  0.37
2020 Reinkemeier CD, Lemke EA. Raising the ribosomal repertoire. Nature Chemistry. 12: 503-504. PMID 32472100 DOI: 10.1038/S41557-020-0476-6  0.352
2020 Paci G, Zheng T, Caria J, Zilman A, Lemke EA. Author response: Molecular determinants of large cargo transport into the nucleus Elife. DOI: 10.7554/Elife.55963.Sa2  0.716
2020 Patsis PA, Celetti G, Paci G, Caria J, Yu M, Scheidt T, VanDelinder V, Bachand G, Lemke EA. Dissecting the Nuclear Pore-Like Permeability Barrier Function of Phase Separated Liquid FG Nucleoporin Condensates Biophysical Journal. 118: 61a. DOI: 10.1016/J.Bpj.2019.11.511  0.695
2020 Reinkemeier CD, Girona GE, Sushkin ME, Lemke EA. Designer Membraneless Organelles Enable Highly Specific Protein Engineering in Eukaryotes Biophysical Journal. 118. DOI: 10.1016/J.Bpj.2019.11.3300  0.303
2020 Caria J, Paci G, Zheng T, Zilman A, Lemke EA. Molecular Determinants of Large Cargo Transport into the Nucleus Biophysical Journal. 118: 342a. DOI: 10.1016/J.Bpj.2019.11.1904  0.721
2020 Koehler C, Reinkemeier CD, Sauter P, Shymanska N, Lemke EA. In Cell Kinetic FRET Assay to Judge Suitability of Bioorthogonal Dye Labelling Reaction Biophysical Journal. 118: 314a. DOI: 10.1016/J.Bpj.2019.11.1767  0.314
2019 Celetti G, Paci G, Caria J, VanDelinder V, Bachand G, Lemke EA. The liquid state of FG-nucleoporins mimics permeability barrier properties of nuclear pore complexes. The Journal of Cell Biology. PMID 31723007 DOI: 10.1083/Jcb.201907157  0.724
2019 Chowdhury A, Yu M, Lemke EA. Phase Separation Comes of Age: From Phenomenology to Single Molecules. Molecular Cell. 74: 413-415. PMID 31051137 DOI: 10.1016/J.Molcel.2019.04.016  0.751
2019 Reinkemeier CD, Girona GE, Lemke EA. Designer membraneless organelles enable codon reassignment of selected mRNAs in eukaryotes. Science (New York, N.Y.). 363. PMID 30923194 DOI: 10.1126/Science.Aaw2644  0.337
2019 Lemke EA, Chowdhury A, Kovalenko SA, Aramburu IV, Tan PS, Ernsting NP. Mechanism dependent modulation of ultrafast interfacial water dynamics in intrinsically disordered protein complexes. Angewandte Chemie (International Ed. in English). PMID 30703278 DOI: 10.1002/Anie.201813354  0.763
2019 Chowdhury A, Kovalenko SA, Aramburu IV, Tan PS, Ernsting NP, Lemke EA. Mechanismusabhängige Regulation der ultraschnellen Dynamik von Wasser an Grenzflächen in Komplexen mit intrinsisch ungeordneten Proteinen Angewandte Chemie. 131: 4769-4774. DOI: 10.1002/Ange.201813354  0.717
2018 Tan PS, Lemke EA. Probing Differential Binding Mechanisms of Phenylalanine-Glycine-Rich Nucleoporins by Single-Molecule FRET. Methods in Enzymology. 611: 327-346. PMID 30471692 DOI: 10.1016/Bs.Mie.2018.08.034  0.421
2018 Hellenkamp B, Schmid S, Doroshenko O, Opanasyuk O, Kühnemuth R, Rezaei Adariani S, Ambrose B, Aznauryan M, Barth A, Birkedal V, Bowen ME, Chen H, Cordes T, Eilert T, Fijen C, ... ... Lemke EA, et al. Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study. Nature Methods. 15: 669-676. PMID 30171252 DOI: 10.1038/S41592-018-0085-0  0.311
2018 Fuertes G, Banterle N, Ruff KM, Chowdhury A, Pappu RV, Svergun DI, Lemke EA. Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water". Science (New York, N.Y.). 361. PMID 30166461 DOI: 10.1126/Science.Aau8230  0.764
2018 Mikhaleva S, Lemke EA. Beyond the Transport Function of Import Receptors: What's All the FUS about? Cell. 173: 549-553. PMID 29677508 DOI: 10.1016/J.Cell.2018.04.002  0.343
2018 Kormos A, Koehler C, Fodor E, Rutkai Z, Martin M, Mező G, Lemke E, Kele P. Bistetrazine-cyanines as double-clicking fluorogenic two-point binder or crosslinker probes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29676491 DOI: 10.1002/Chem.201800910  0.394
2018 Tan PS, Aramburu IV, Mercadante D, Tyagi S, Chowdhury A, Spitz D, Shammas SL, Gräter F, Lemke EA. Two Differential Binding Mechanisms of FG-Nucleoporins and Nuclear Transport Receptors. Cell Reports. 22: 3660-3671. PMID 29590630 DOI: 10.1016/J.Celrep.2018.03.022  0.761
2018 Kozma E, Paci G, Estrada Girona G, Lemke EA, Kele P. Fluorogenic Tetrazine-Siliconrhodamine Probe for the Labeling of Noncanonical Amino Acid Tagged Proteins. Methods in Molecular Biology (Clifton, N.J.). 1728: 337-363. PMID 29405009 DOI: 10.1007/978-1-4939-7574-7_22  0.785
2018 Koehler C, Lemke EA. MultiBacTAG-Genetic Code Expansion Using the Baculovirus Expression System in Sf21 Cells. Methods in Molecular Biology (Clifton, N.J.). 1728: 297-311. PMID 29405006 DOI: 10.1007/978-1-4939-7574-7_19  0.351
2018 Brabham RL, Spears RJ, Walton J, Tyagi S, Lemke EA, Fascione MA. Palladium-unleashed proteins: gentle aldehyde decaging for site-selective protein modification. Chemical Communications (Cambridge, England). PMID 29363688 DOI: 10.1039/C7Cc07740H  0.362
2018 Kozma E, Estrada Girona G, Paci G, Lemke EA, Kele P. Bioorthogonal double-fluorogenic siliconrhodamine probes for intracellular super-resolution microscopy. Chemical Communications (Cambridge, England). 53: 6696-6699. PMID 28530747 DOI: 10.1039/C7Cc02212C  0.756
2018 Ruff KM, Fuertes G, Banterle N, Svergun DI, Lemke EA, Pappu RV. Sequence-Encoded Heterogeneity of Interactions Decouples Different Measures of Protein Sizes and Reconciles the Discrepant Inferences from Saxs versus Fret Experiments Biophysical Journal. 114: 368a. DOI: 10.1016/J.Bpj.2017.11.2039  0.304
2018 Wawryszyn M, Sauter PF, Nieger M, Koos MRM, Koehler C, Luy B, Lemke EA, Bräse S. Synthesis of Azido-Glycans for Chemical Glycomodification of Proteins European Journal of Organic Chemistry. 2018: 4296-4305. DOI: 10.1002/Ejoc.201800602  0.333
2017 Warner JB, Ruff K, Tan PS, Lemke EA, Pappu RV, Lashuel HA. Monomeric huntingtin exon 1 has similar overall structural features for wild type and pathological polyglutamine lengths. Journal of the American Chemical Society. PMID 28937758 DOI: 10.1021/Jacs.7B06659  0.32
2017 Fuertes G, Banterle N, Ruff KM, Chowdhury A, Mercadante D, Koehler C, Kachala M, Estrada Girona G, Milles S, Mishra A, Onck PR, Gräter F, Esteban-Martín S, Pappu RV, Svergun DI, ... Lemke EA, et al. Decoupling of size and shape fluctuations in heteropolymeric sequences reconciles discrepancies in SAXS vs. FRET measurements. Proceedings of the National Academy of Sciences of the United States of America. PMID 28716919 DOI: 10.1073/Pnas.1704692114  0.787
2017 Aramburu IV, Lemke EA. Floppy but not sloppy: Interaction mechanism of FG-Nucleoporins and nuclear transport receptors. Seminars in Cell & Developmental Biology. PMID 28669824 DOI: 10.1016/J.Semcdb.2017.06.026  0.321
2017 Sakin V, Hanne J, Dunder J, Anders-Össwein M, Laketa V, Nikić I, Kräusslich HG, Lemke EA, Müller B. A Versatile Tool for Live-Cell Imaging and Super-Resolution Nanoscopy Studies of HIV-1 Env Distribution and Mobility. Cell Chemical Biology. PMID 28457706 DOI: 10.1016/J.Chembiol.2017.04.007  0.766
2017 Demeter O, Kormos A, Koehler C, Mezõ G, Németh K, Kozma E, Takacs L, Lemke EA, Kele P. BISAZIDE CYANINE DYES AS FLUOROGENIC PROBES FOR BIS-CYCLOOCTYNYLATED PEPTIDE TAGS AND AS FLUOROGENIC CROSSLINKERS OF CYCLOOCTYNYLATED PROTEINS. Bioconjugate Chemistry. PMID 28441009 DOI: 10.1021/Acs.Bioconjchem.7B00178  0.356
2017 Paci G, Lemke EA. Shining a Light on Phase Separation in the Cell. Cell. 168: 11-13. PMID 28086083 DOI: 10.1016/J.Cell.2016.12.018  0.714
2017 Ann Metskas L, Paci G, Lemke EA, Briggs JA. Incorporating Single-Particle Biophysics into Correlated Cryo-Fluorescence and Cryo-Electron Microscopy Biophysical Journal. 112: 578a. DOI: 10.1016/J.Bpj.2016.11.3111  0.723
2017 Siong Tan P, Valle Aramburu I, Tyagi S, Chowdhury A, Lemke EA. Dissecting Conformational Features and Binding Mechanisms of Phenylalanine-Glycine Rich Nucleoporins Biophysical Journal. 112: 511a. DOI: 10.1016/J.Bpj.2016.11.2761  0.736
2017 Paci G, Banterle N, Koehler C, Lemke EA. Following a Giant's Footsteps: Single-Particle and Super-Resolution Approaches to Decipher the Nuclear Transport of Hepatitis B Virus Capsids Biophysical Journal. 112: 20a-21a. DOI: 10.1016/J.Bpj.2016.11.144  0.751
2017 Chowdhury A, Aramburu IV, Siong Tan P, Lemke EA. Surface Solvation Tunes Molecular-Recognition Plasticity in IDPs Biophysical Journal. 112: 206a. DOI: 10.1016/J.Bpj.2016.11.1139  0.771
2016 Kucher S, Korneev S, Tyagi S, Apfelbaum R, Grohmann D, Lemke EA, Klare JP, Steinhoff HJ, Klose D. Orthogonal spin labeling using click chemistry for in vitro and in vivo applications. Journal of Magnetic Resonance (San Diego, Calif. : 1997). 275: 38-45. PMID 27992783 DOI: 10.1016/J.Jmr.2016.12.001  0.325
2016 Nikić I, Estrada Girona G, Kang JH, Paci G, Mikhaleva S, Koehler C, Shymanska NV, Ventura Santos C, Spitz D, Lemke EA. Debugging Eukaryotic Genetic Code Expansion for Site-Specific Click-PAINT Super-Resolution Microscopy. Angewandte Chemie (International Ed. in English). PMID 27804198 DOI: 10.1002/Anie.201608284  0.81
2016 Kipper K, Lundius EG, Curic V, Nikic I, Lemke EA, Wiessler M, Elf J. Application of noncanonical amino acids for protein labeling in a genomically recoded Escherichia coli. Acs Synthetic Biology. PMID 27775882 DOI: 10.1021/Acssynbio.6B00138  0.781
2016 Koehler C, Sauter PF, Wawryszyn M, Girona GE, Gupta K, Landry JJ, Fritz MH, Radic K, Hoffmann JE, Chen ZA, Zou J, Tan PS, Galik B, Junttila S, Stolt-Bergner P, ... ... Lemke EA, et al. Genetic code expansion for multiprotein complex engineering. Nature Methods. PMID 27749839 DOI: 10.1038/Nmeth.4032  0.427
2016 Kozma E, Nikic I, Varga BR, Aramburu IV, Kang JH, Fackler OT, Lemke EA, Kele P. Hydrophilic trans-Cyclooctenylated Non-Canonical Amino Acids for Fast Intracellular Protein Labeling. Chembiochem : a European Journal of Chemical Biology. PMID 27223658 DOI: 10.1002/Cbic.201600284  0.814
2016 Knorr G, Kozma E, Herner A, Lemke EA, Kele P. New Red-Emitting Tetrazine-Phenoxazine Fluorogenic Labels for Live-Cell Intracellular Bioorthogonal Labeling Schemes. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27218228 DOI: 10.1002/Chem.201600590  0.422
2016 Banterle N, Lemke EA. Nanoscale devices for linkerless long-term single-molecule observation. Current Opinion in Biotechnology. 39: 105-12. PMID 26990172 DOI: 10.1016/J.Copbio.2016.02.013  0.347
2016 Sakin V, Paci G, Lemke EA, Müller B. Labeling of virus components for advanced, quantitative imaging analyses. Febs Letters. PMID 26987299 DOI: 10.1002/1873-3468.12131  0.738
2016 Lemke EA. The Multiple Faces of Disordered Nucleoporins. Journal of Molecular Biology. 428: 2011-24. PMID 26791761 DOI: 10.1016/J.Jmb.2016.01.002  0.361
2016 Mercadante D, Milles S, Fuertes G, Svergun D, Lemke EA, Gräter F. Rescuing the Over-Collapse of Intrinsically Disordered Proteins using a Force Field Derived by a New Paradigm Biophysical Journal. 110: 556a. DOI: 10.1016/J.Bpj.2015.11.2974  0.315
2016 Hee Kang J, Nikić I, Estrada Girona G, Lemke EA. Site-Specific Labeling of Proteins in Live Mammalian Cells using Click Chemistry Biophysical Journal. 110: 485a. DOI: 10.1016/J.Bpj.2015.11.2594  0.798
2016 Valle Aramburu I, Mercadante D, Milles S, Ringkjøbing M, Banterle N, Koehler C, Tyagi S, Clarke J, Shammas SL, Blackledge M, Gräter F, Lemke EA. Plasticity of Nucleoporin Nuclear Transport Receptor Interactions - Molecular Description of a Highly Dynamic, Ultrafast Interaction Mechanism Biophysical Journal. 110: 357a. DOI: 10.1016/J.Bpj.2015.11.1927  0.362
2016 Koehler C, Sauter P, Wawryszyn M, Estrada Girona G, Fritz MH, Biskup M, Besir H, Berger I, Benes V, Korbel J, Braese S, Lemke EA. A New Tool for Custom Protein Design and Engineering - DH10 Bac-TAG Biophysical Journal. 110: 345a. DOI: 10.1016/J.Bpj.2015.11.1856  0.42
2016 Koehler C, Lemke EA. Neue seitenspezifische Proteinfunktionalität mit einem Klick Biospektrum. 22: 704-707. DOI: 10.1007/S12268-016-0747-3  0.404
2016 Kozma E, Nikić I, Varga BR, Aramburu IV, Kang JH, Fackler OT, Lemke EA, Kele P. Inside Cover: Hydrophilic trans -Cyclooctenylated Noncanonical Amino Acids for Fast Intracellular Protein Labeling (ChemBioChem 16/2016) Chembiochem. 17: 1483-1483. DOI: 10.1002/Cbic.201600409  0.795
2016 Nikić I, Estrada Girona G, Kang JH, Paci G, Mikhaleva S, Koehler C, Shymanska NV, Ventura Santos C, Spitz D, Lemke EA. Cover Picture: Debugging Eukaryotic Genetic Code Expansion for Site-Specific Click-PAINT Super-Resolution Microscopy (Angew. Chem. Int. Ed. 52/2016) Angewandte Chemie International Edition. 55: 15931-15931. DOI: 10.1002/Anie.201611395  0.762
2016 Nikić I, Estrada Girona G, Kang JH, Paci G, Mikhaleva S, Koehler C, Shymanska NV, Ventura Santos C, Spitz D, Lemke EA. Titelbild: Verbesserte Erweiterung des eukaryotischen genetischen Codes für seitenspezifische, hochauflösende Click-PAINT-Mikroskopie (Angew. Chem. 52/2016) Angewandte Chemie. 128: 16163-16163. DOI: 10.1002/Ange.201611395  0.743
2016 Nikić I, Estrada Girona G, Kang JH, Paci G, Mikhaleva S, Koehler C, Shymanska NV, Ventura Santos C, Spitz D, Lemke EA. Verbesserte Erweiterung des eukaryotischen genetischen Codes für seitenspezifische, hochauflösende Click-PAINT-Mikroskopie Angewandte Chemie. 128: 16406-16410. DOI: 10.1002/Ange.201608284  0.765
2015 Vreja IC, Nikić I, Göttfert F, Bates M, Kröhnert K, Outeiro TF, Hell SW, Lemke EA, Rizzoli SO. Super-resolution Microscopy of Clickable Amino Acids Reveals the Effects of Fluorescent Protein Tagging on Protein Assemblies. Acs Nano. PMID 26498474 DOI: 10.1021/Acsnano.5B04434  0.787
2015 Milles S, Mercadante D, Aramburu IV, Jensen MR, Banterle N, Koehler C, Tyagi S, Clarke J, Shammas SL, Blackledge M, Gräter F, Lemke EA. Plasticity of an Ultrafast Interaction between Nucleoporins and Nuclear Transport Receptors. Cell. 163: 734-45. PMID 26456112 DOI: 10.1016/J.Cell.2015.09.047  0.386
2015 Delaforge E, Milles S, Bouvignies G, Bouvier D, Boivin S, Salvi N, Maurin D, Martel A, Round A, Lemke EA, Ringkjøbing Jensen M, Hart DJ, Blackledge M. Large-Scale Conformational Dynamics Control H5N1 Influenza Polymerase PB2 Binding to Importin α. Journal of the American Chemical Society. PMID 26424125 DOI: 10.1021/Jacs.5B07765  0.309
2015 von Appen A, Kosinski J, Sparks L, Ori A, DiGuilio AL, Vollmer B, Mackmull MT, Banterle N, Parca L, Kastritis P, Buczak K, Mosalaganti S, Hagen W, Andres-Pons A, Lemke EA, et al. In situ structural analysis of the human nuclear pore complex. Nature. 526: 140-3. PMID 26416747 DOI: 10.1038/Nature15381  0.316
2015 Nikić I, Lemke EA. Genetic code expansion enabled site-specific dual-color protein labeling: superresolution microscopy and beyond. Current Opinion in Chemical Biology. 28: 164-73. PMID 26302384 DOI: 10.1016/J.Cbpa.2015.07.021  0.798
2015 Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C. Frontispiece: Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling. Chemistry (Weinheim An Der Bergstrasse, Germany). 21. PMID 26284950 DOI: 10.1002/Chem.201583561  0.751
2015 Wagner JA, Mercadante D, Nikić I, Lemke EA, Gräter F. Origin of Orthogonality of Strain-Promoted Click Reactions. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 12431-5. PMID 26178299 DOI: 10.1002/Chem.201501727  0.728
2015 Hoffmann JE, Plass T, Nikić I, Aramburu IV, Koehler C, Gillandt H, Lemke EA, Schultz C. Highly Stable trans-Cyclooctene Amino Acids for Live-Cell Labeling. Chemistry (Weinheim An Der Bergstrasse, Germany). 21: 12266-70. PMID 26177861 DOI: 10.1002/Chem.201501647  0.759
2015 Mercadante D, Milles S, Fuertes G, Svergun DI, Lemke EA, Gräter F. Kirkwood-Buff Approach Rescues Overcollapse of a Disordered Protein in Canonical Protein Force Fields. The Journal of Physical Chemistry. B. 119: 7975-84. PMID 26030189 DOI: 10.1021/Acs.Jpcb.5B03440  0.361
2015 Niki? I, Kang JH, Girona GE, Aramburu IV, Lemke EA. Labeling proteins on live mammalian cells using click chemistry. Nature Protocols. 10: 780-91. PMID 25906116 DOI: 10.1038/Nprot.2015.045  0.734
2015 Tyagi S, Lemke EA. Single-molecule FRET and crosslinking studies in structural biology enabled by noncanonical amino acids. Current Opinion in Structural Biology. 32: 66-73. PMID 25757192 DOI: 10.1016/J.Sbi.2015.02.009  0.373
2015 von Voithenberg LV, Barth A, Tyagi S, Koehler C, Lemke EA, Lamb DC. Conformational Dynamics of Molecular Chaperones Investigated by Single Molecule Multicolor Förster Resonance Energy Transfer Biophysical Journal. 108: 501a-502a. DOI: 10.1016/J.Bpj.2014.11.2748  0.387
2015 Mercadante D, Milles S, Lemke EA, Gräter F. A New and Un-Conventional Ultrafast Binding Mechanism of Intrinsically Disordered Proteins to Structured Partners Biophysical Journal. 108: 193a. DOI: 10.1016/J.Bpj.2014.11.1067  0.33
2015 Lemke EA. Decoding Protein Plasticity from Single Molecules to Large Complexes Biophysical Journal. 108: 5a-6a. DOI: 10.1016/J.Bpj.2014.11.046  0.391
2015 Wagner JA, Mercadante D, Nikic I, Lemke EA, Gräter F. Origin of Orthogonality of Strain-Promoted Click Reactions Chemistry - a European Journal. 21: 12431-12435. DOI: 10.1002/chem.201501727  0.684
2014 Lemke EA. The exploding genetic code. Chembiochem : a European Journal of Chemical Biology. 15: 1691-4. PMID 25079784 DOI: 10.1002/Cbic.201402362  0.329
2014 Herner A, Estrada Girona G, Nikić I, Kállay M, Lemke EA, Kele P. New generation of bioorthogonally applicable fluorogenic dyes with visible excitations and large Stokes shifts. Bioconjugate Chemistry. 25: 1370-4. PMID 24932756 DOI: 10.1021/Bc500235P  0.77
2014 Milles S, Lemke EA. Mapping multivalency and differential affinities within large intrinsically disordered protein complexes with segmental motion analysis. Angewandte Chemie (International Ed. in English). 53: 7364-7. PMID 24898547 DOI: 10.1002/Anie.201403694  0.36
2014 Pavic K, Rios P, Dzeyk K, Koehler C, Lemke EA, Köhn M. Unnatural amino acid mutagenesis reveals dimerization as a negative regulatory mechanism of VHR's phosphatase activity. Acs Chemical Biology. 9: 1451-9. PMID 24798147 DOI: 10.1021/Cb500240N  0.306
2014 Nikić I, Plass T, Schraidt O, SzymaÅ„ski J, Briggs JA, Schultz C, Lemke EA. Minimal tags for rapid dual-color live-cell labeling and super-resolution microscopy. Angewandte Chemie (International Ed. in English). 53: 2245-9. PMID 24474648 DOI: 10.1002/Anie.201309847  0.45
2014 Tyagi S, VanDelinder V, Banterle N, Fuertes G, Milles S, Agez M, Lemke EA. Continuous throughput and long-term observation of single-molecule FRET without immobilization. Nature Methods. 11: 297-300. PMID 24441935 DOI: 10.1038/Nmeth.2809  0.342
2014 Lemke EA. Decoding Molecular Plasticity Underlying Nucleocytoplasmic Transport: from Single Molecules to Large Assemblies Biophysical Journal. 106: 35a. DOI: 10.1016/J.Bpj.2013.11.270  0.416
2014 Milles S, Lemke EA. Detektion von Mehrbindigkeit und differenziellen Affinitäten in großen, intrinsisch ungeordneten Proteinen mithilfe von Segmentbewegungsanalyse Angewandte Chemie. 126: 7492-7496. DOI: 10.1002/Ange.201403694  0.301
2014 Nikić I, Plass T, Schraidt O, Szymański J, Briggs JAG, Schultz C, Lemke EA. Schnelle, zweifarbige Proteinmarkierung an lebenden Zellen für die hochauflösende Mikroskopie Angewandte Chemie. 126: 2278-2282. DOI: 10.1002/Ange.201309847  0.728
2013 Herner A, Nikić I, Kállay M, Lemke EA, Kele P. A new family of bioorthogonally applicable fluorogenic labels. Organic & Biomolecular Chemistry. 11: 3297-306. PMID 23535909 DOI: 10.1039/C3Ob40296G  0.762
2013 Ori A, Banterle N, Iskar M, Andrés-Pons A, Escher C, Khanh Bui H, Sparks L, Solis-Mezarino V, Rinner O, Bork P, Lemke EA, Beck M. Cell type-specific nuclear pores: a case in point for context-dependent stoichiometry of molecular machines. Molecular Systems Biology. 9: 648. PMID 23511206 DOI: 10.1038/Msb.2013.4  0.334
2013 Lukinavičius G, Umezawa K, Olivier N, Honigmann A, Yang G, Plass T, Mueller V, Reymond L, Corrêa IR, Luo ZG, Schultz C, Lemke EA, Heppenstall P, Eggeling C, Manley S, et al. A near-infrared fluorophore for live-cell super-resolution microscopy of cellular proteins. Nature Chemistry. 5: 132-9. PMID 23344448 DOI: 10.1038/Nchem.1546  0.625
2013 Tyagi S, Lemke EA. Genetically encoded click chemistry for single-molecule FRET of proteins. Methods in Cell Biology. 113: 169-87. PMID 23317903 DOI: 10.1016/B978-0-12-407239-8.00009-4  0.491
2013 Milles S, Huy Bui K, Koehler C, Eltsov M, Beck M, Lemke EA. Facilitated aggregation of FG nucleoporins under molecular crowding conditions. Embo Reports. 14: 178-83. PMID 23238392 DOI: 10.1038/Embor.2012.204  0.316
2013 Milles S, Lemke EA. What precision-protein-tuning and nano-resolved single molecule sciences can do for each other. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. 35: 65-74. PMID 23147190 DOI: 10.1002/Bies.201200094  0.399
2013 Milles S, Lemke EA. Nup153 in Nuclear Transport: Plasticity of Nucleoporin/Transport-Receptor Complexes Biophysical Journal. 104: 30a. DOI: 10.1016/J.Bpj.2012.11.202  0.425
2013 Banterle N, Ori A, Andres-Pons A, Beck M, Lemke EA. Absolute Stoichiometry of the Nuclear Pore Complex Biophysical Journal. 104: 342a. DOI: 10.1016/J.Bpj.2012.11.1898  0.383
2013 Milles S, Tyagi S, Plass T, Koehler C, Schultz C, Lemke EA. Labeling Freedom for the Single Molecule Microscopist Biophysical Journal. 104: 576a. DOI: 10.1016/J.Bpj.2011.11.1187  0.5
2012 Borrmann A, Milles S, Plass T, Dommerholt J, Verkade JM, Wiessler M, Schultz C, van Hest JC, van Delft FL, Lemke EA. Genetic encoding of a bicyclo[6.1.0]nonyne-charged amino acid enables fast cellular protein imaging by metal-free ligation. Chembiochem : a European Journal of Chemical Biology. 13: 2094-9. PMID 22945333 DOI: 10.1002/Cbic.201200407  0.395
2012 Krishnan R, Goodman JL, Mukhopadhyay S, Pacheco CD, Lemke EA, Deniz AA, Lindquist S. Conserved features of intermediates in amyloid assembly determine their benign or toxic states. Proceedings of the National Academy of Sciences of the United States of America. 109: 11172-7. PMID 22745165 DOI: 10.1073/Pnas.1209527109  0.725
2012 Milles S, Koehler C, Gambin Y, Deniz AA, Lemke EA. Intramolecular three-colour single pair FRET of intrinsically disordered proteins with increased dynamic range. Molecular Biosystems. 8: 2531-4. PMID 22739670 DOI: 10.1039/C2Mb25135C  0.774
2012 Milles S, Tyagi S, Banterle N, Koehler C, VanDelinder V, Plass T, Neal AP, Lemke EA. Click strategies for single-molecule protein fluorescence. Journal of the American Chemical Society. 134: 5187-95. PMID 22356317 DOI: 10.1021/Ja210587Q  0.476
2012 VanDelinder V, Banterle N, Agez M, Tyagi S, Fuertes G, Milles S, Lemke EA. Long Term Single Molecule TIRF Observation of Biomolecules without Immobilization Biophysical Journal. 102: 178a. DOI: 10.1016/J.Bpj.2011.11.966  0.338
2011 Milles S, Lemke EA. Single molecule study of the intrinsically disordered FG-repeat nucleoporin 153. Biophysical Journal. 101: 1710-9. PMID 21961597 DOI: 10.1016/J.Bpj.2011.08.025  0.304
2011 Lemke EA. Site-specific labeling of proteins for single-molecule FRET measurements using genetically encoded ketone functionalities. Methods in Molecular Biology (Clifton, N.J.). 751: 3-15. PMID 21674321 DOI: 10.1007/978-1-61779-151-2_1  0.478
2011 Plass T, Milles S, Koehler C, Schultz C, Lemke EA. Genetically encoded copper-free click chemistry. Angewandte Chemie (International Ed. in English). 50: 3878-81. PMID 21433234 DOI: 10.1002/Anie.201008178  0.436
2011 Gambin Y, VanDelinder V, Ferreon AC, Lemke EA, Groisman A, Deniz AA. Visualizing a one-way protein encounter complex by ultrafast single-molecule mixing. Nature Methods. 8: 239-41. PMID 21297620 DOI: 10.1038/Nmeth.1568  0.768
2010 Gambin Y, Lemke EA, Vandelinder V, Groisman A, Deniz AA. High-Resolution smFRET in a Microfluidic Gas Exchange Platform Biophysical Journal. 98: 622a-623a. DOI: 10.1016/J.Bpj.2009.12.3407  0.747
2009 Lemke EA, Gambin Y, Vandelinder V, Brustad EM, Liu HW, Schultz PG, Groisman A, Deniz AA. Microfluidic device for single-molecule experiments with enhanced photostability. Journal of the American Chemical Society. 131: 13610-2. PMID 19772358 DOI: 10.1021/Ja9027023  0.769
2009 Lee HS, Guo J, Lemke EA, Dimla RD, Schultz PG. Genetic incorporation of a small, environmentally sensitive, fluorescent probe into proteins in Saccharomyces cerevisiae. Journal of the American Chemical Society. 131: 12921-3. PMID 19702307 DOI: 10.1021/Ja904896S  0.769
2009 Gambin Y, Schug A, Lemke EA, Lavinder JJ, Ferreon AC, Magliery TJ, Onuchic JN, Deniz AA. Direct single-molecule observation of a protein living in two opposed native structures. Proceedings of the National Academy of Sciences of the United States of America. 106: 10153-8. PMID 19506258 DOI: 10.1073/Pnas.0904461106  0.789
2009 Ferreon AC, Gambin Y, Lemke EA, Deniz AA. Interplay of alpha-synuclein binding and conformational switching probed by single-molecule fluorescence. Proceedings of the National Academy of Sciences of the United States of America. 106: 5645-50. PMID 19293380 DOI: 10.1073/Pnas.0809232106  0.744
2008 Brustad EM, Lemke EA, Schultz PG, Deniz AA. A general and efficient method for the site-specific dual-labeling of proteins for single molecule fluorescence resonance energy transfer. Journal of the American Chemical Society. 130: 17664-5. PMID 19108697 DOI: 10.1021/Ja807430H  0.811
2008 Deniz AA, Mukhopadhyay S, Lemke EA. Single-molecule biophysics: at the interface of biology, physics and chemistry. Journal of the Royal Society, Interface / the Royal Society. 5: 15-45. PMID 17519204 DOI: 10.1098/Rsif.2007.1021  0.752
2007 Lemke EA, Summerer D, Geierstanger BH, Brittain SM, Schultz PG. Control of protein phosphorylation with a genetically encoded photocaged amino acid Nature Chemical Biology. 3: 769-772. PMID 17965709 DOI: 10.1038/Nchembio.2007.44  0.688
2007 Mukhopadhyay S, Krishnan R, Lemke EA, Lindquist S, Deniz AA. A natively unfolded yeast prion monomer adopts an ensemble of collapsed and rapidly fluctuating structures. Proceedings of the National Academy of Sciences of the United States of America. 104: 2649-54. PMID 17299036 DOI: 10.1073/Pnas.0611503104  0.761
2006 Takamori S, Holt M, Stenius K, Lemke EA, Grønborg M, Riedel D, Urlaub H, Schenck S, Brügger B, Ringler P, Müller SA, Rammner B, Gräter F, Hub JS, De Groot BL, et al. Molecular anatomy of a trafficking organelle. Cell. 127: 831-46. PMID 17110340 DOI: 10.1016/J.Cell.2006.10.030  0.349
2003 Chakraborty R, Lemke EA, Cao Z, Klebba PE, van der Helm D. Identification and mutational studies of conserved amino acids in the outer membrane receptor protein, FepA, which affect transport but not binding of ferric-enterobactin in Escherichia coli. Biometals : An International Journal On the Role of Metal Ions in Biology, Biochemistry, and Medicine. 16: 507-18. PMID 12779236 DOI: 10.1023/A:1023485632520  0.371
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