James E. Trosko - Publications

Affiliations: 
Michigan State University, East Lansing, MI 
Area:
Genetics, Cell Biology, Oncology

254 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Hatabi K, Hirohara Y, Kushida Y, Kuroda Y, Wakao S, Trosko J, Dezawa M. Inhibition of Gap Junctional Intercellular Communication Upregulates Pluripotency Gene Expression in Endogenous Pluripotent Muse Cells. Cells. 11. PMID 36078111 DOI: 10.3390/cells11172701  0.337
2021 Trosko JE. The Concept of "Cancer Stem Cells" in the Context of Classic Carcinogenesis Hypotheses and Experimental Findings. Life (Basel, Switzerland). 11. PMID 34947839 DOI: 10.3390/life11121308  0.321
2020 Basu A, Dydowiczová A, Trosko JE, Bláha L, Babica P. Ready to go 3D? A semi-automated protocol for microwell spheroid arrays to increase scalability and throughput of 3D cell culture testing. Toxicology Mechanisms and Methods. 1-43. PMID 32713235 DOI: 10.1080/15376516.2020.1800881  0.37
2019 Leone A, Longo C, Gerardi C, Trosko JE. Pro-Apoptotic Effect of Grape Seed Extract on MCF-7 Involves Transient Increase of Gap Junction Intercellular Communication and Cx43 Up-Regulation: A Mechanism of Chemoprevention. International Journal of Molecular Sciences. 20. PMID 31269652 DOI: 10.3390/Ijms20133244  0.446
2019 Trosko JE. Cancer Prevention and Therapy of Two Types of Gap Junctional Intercellular Communication⁻Deficient "Cancer Stem Cell". Cancers. 11. PMID 30646567 DOI: 10.3390/Cancers11010087  0.405
2018 Trosko JE. The Role of the Mitochondria in the Evolution of Stem Cells, Including MUSE Stem Cells and Their Biology. Advances in Experimental Medicine and Biology. 1103: 131-152. PMID 30484227 DOI: 10.1007/978-4-431-56847-6_7  0.409
2018 Trosko JE. A Historical Perspective for the Development of Mechanistic-Based 3D Models of Toxicology Using Human Adult Stem Cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 165: 6-9. PMID 30325469 DOI: 10.1093/Toxsci/Kfy168  0.319
2018 Basu A, Dydowiczova A, Ctverackova L, Jasa L, Trosko JE, Blaha L, Babica P. Assessment of hepatotoxic potential of cyanobacterial toxins using 3D in vitro model of adult human liver stem cells. Environmental Science & Technology. PMID 30059226 DOI: 10.1021/Acs.Est.8B02291  0.365
2017 Carruba G, Trosko JE. The Long Evolutionary Journey of Cancer from Ancestor to Modern Humans. Critical Reviews in Oncogenesis. 22: 323-352. PMID 29604908 DOI: 10.1615/Critrevoncog.2018025227  0.391
2017 Trosko JE, Carruba G. "Bad Luck Mutations": DNA Mutations Are not the Whole Answer to Understanding Cancer Risk. Dose-Response : a Publication of International Hormesis Society. 15: 1559325817716585. PMID 28717349 DOI: 10.1177/1559325817716585  0.385
2017 Trosko JE, Lenz HJ. What roles do colon stem cells and gap junctions play in the left and right location of origin of colorectal cancers? Journal of Cell Communication and Signaling. PMID 28220297 DOI: 10.1007/S12079-017-0381-Y  0.362
2016 Lopes J, Arnosti D, Trosko JE, Tai MH, Zuccari D. Melatonin decreases estrogen receptor binding to estrogen response elements sites on the OCT4 gene in human breast cancer stem cells. Genes & Cancer. 7: 209-17. PMID 27551335 DOI: 10.18632/Genesandcancer.107  0.369
2016 Babica P, Zurabian R, Kumar ER, Chopra R, Mianecki MJ, Park JS, Jaša L, Trosko JE, Upham BL. Methoxychlor and vinclozolin induce rapid changes in intercellular and intracellular signaling in liver progenitor cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27413106 DOI: 10.1093/Toxsci/Kfw114  0.382
2016 Trosko JE. Evolution of Microbial Quorum Sensing to Human Global Quorum Sensing: An Insight into How Gap Junctional Intercellular Communication Might Be Linked to the Global Metabolic Disease Crisis. Biology. 5. PMID 27314399 DOI: 10.3390/Biology5020029  0.416
2016 Babica P, Čtveráčková L, Lenčešová Z, Trosko JE, Upham BL. Chemopreventive Agents Attenuate Rapid Inhibition of Gap Junctional Intercellular Communication Induced by Environmental Toxicants. Nutrition and Cancer. 1-11. PMID 27266532 DOI: 10.1080/01635581.2016.1180409  0.398
2016 Trosko JE. A Conceptual Integration of Extra-, Intra- and Gap Junctional- Intercellular Communication in the Evolution of Multi-cellularity and Stem Cells: How Disrupted Cell-Cell Communication during Development can Affect Diseases later in Life International Journal of Stem Cell Research & Therapy. 3. DOI: 10.23937/2469-570X/1410021  0.462
2015 Sovadinova I, Babica P, Böke H, Kumar E, Wilke A, Park JS, Trosko JE, Upham BL. Phosphatidylcholine Specific PLC-Induced Dysregulation of Gap Junctions, a Robust Cellular Response to Environmental Toxicants, and Prevention by Resveratrol in a Rat Liver Cell Model. Plos One. 10: e0124454. PMID 26023933 DOI: 10.1371/Journal.Pone.0137599  0.351
2014 Trosko JE. Induction of iPS cells and of cancer stem cells: the stem cell or reprogramming hypothesis of cancer? Anatomical Record (Hoboken, N.J. : 2007). 297: 161-73. PMID 24293264 DOI: 10.1002/Ar.22793  0.412
2013 Trosko JE. Evolution of energy metabolism, stem cells and cancer stem cells: how the Warburg and Barker hypothesis might be linked. Bmc Proceedings. 7: K8. PMID 24764487 DOI: 10.1186/1753-6561-7-S2-K8  0.425
2013 Hirabayashi Y, Tsuboi I, Yoon B, Kanno J, Trosko J, Inoue T. Role Of Connexin 32 In Hematopoiesis: Maintaining Quiescence Of Hematopoietic Stem Cells and Their Proliferation Blood. 122: 1185-1185. DOI: 10.1182/Blood.V122.21.1185.1185  0.367
2012 Trosko JE, Kang KS. Evolution of energy metabolism, stem cells and cancer stem cells: how the warburg and barker hypotheses might be linked. International Journal of Stem Cells. 5: 39-56. PMID 24298354 DOI: 10.15283/Ijsc.2012.5.1.39  0.383
2012 Yang SR, Rahman I, Trosko JE, Kang KS. Oxidative stress-induced biomarkers for stem cell-based chemical screening. Preventive Medicine. 54: S42-9. PMID 22197760 DOI: 10.1016/J.Ypmed.2011.11.013  0.351
2012 Scheer MB, Stempin S, Chang C, Trosko J, Lampen A. Human breast stem cells as a toxicological model for endocrine disruptors, such as soy isoflavones Toxicology Letters. 211: S102-S103. DOI: 10.1016/J.Toxlet.2012.03.383  0.309
2012 Leone A, Longo C, Trosko JE. The chemopreventive role of dietary phytochemicals through gap junctional intercellular communication Phytochemistry Reviews. 11: 285-307. DOI: 10.1007/S11101-012-9235-7  0.415
2011 Jung JW, Park SB, Lee SJ, Seo MS, Trosko JE, Kang KS. Metformin represses self-renewal of the human breast carcinoma stem cells via inhibition of estrogen receptor-mediated OCT4 expression. Plos One. 6: e28068. PMID 22132214 DOI: 10.1371/Journal.Pone.0028068  0.355
2011 Trosko JE. The gap junction as a "Biological Rosetta Stone": implications of evolution, stem cells to homeostatic regulation of health and disease in the Barker hypothesis. Journal of Cell Communication and Signaling. 5: 53-66. PMID 21484590 DOI: 10.1007/S12079-010-0108-9  0.438
2011 Kang KS, Trosko JE. Stem cells in toxicology: fundamental biology and practical considerations. Toxicological Sciences : An Official Journal of the Society of Toxicology. 120: S269-89. PMID 21163910 DOI: 10.1093/Toxsci/Kfq370  0.411
2011 Trosko JE. Pre-Natal Epigenetic Influences on Acute and Chronic Diseases Later in Life, such as Cancer: Global Health Crises Resulting from a Collision of Biological and Cultural Evolution Preventive Nutrition and Food Science. 16: 394-407. DOI: 10.3746/Jfn.2011.16.4.394  0.312
2010 Trosko JE, Upham BL. A paradigm shift is required for the risk assessment of potential human health after exposure to low level chemical exposures: a response to the toxicity testing in the 21st century report. International Journal of Toxicology. 29: 344-57. PMID 20634539 DOI: 10.1177/1091581810371384  0.421
2010 Trosko JE. Commentary on ''Toxicity testing in the 21st century: a vision and a strategy'': stem cells and cell-cell communication as fundamental targets in assessing the potential toxicity of chemicals. Human & Experimental Toxicology. 29: 21-9. PMID 20061464 DOI: 10.1177/0960327109354663  0.425
2010 Trosko JE, Chang CC. Factors to consider in the use of stem cells for pharmaceutic drug development and for chemical safety assessment. Toxicology. 270: 18-34. PMID 19948204 DOI: 10.1016/J.Tox.2009.11.019  0.433
2009 Upham BL, Park JS, Babica P, Sovadinova I, Rummel AM, Trosko JE, Hirose A, Hasegawa R, Kanno J, Sai K. Structure-activity-dependent regulation of cell communication by perfluorinated fatty acids using in vivo and in vitro model systems Environmental Health Perspectives. 117: 545-551. PMID 19440492 DOI: 10.1289/Ehp.11728  0.409
2009 Trosko JE. Review paper: cancer stem cells and cancer nonstem cells: from adult stem cells or from reprogramming of differentiated somatic cells. Veterinary Pathology. 46: 176-93. PMID 19261629 DOI: 10.1354/Vp.46-2-176  0.403
2009 Cocciadiferro L, Miceli V, Kang KS, Polito LM, Trosko JE, Carruba G. Profiling cancer stem cells in androgen-responsive and refractory human prostate tumor cell lines. Annals of the New York Academy of Sciences. 1155: 257-62. PMID 19250213 DOI: 10.1111/J.1749-6632.2009.03696.X  0.436
2009 Kawasaki A, Hayashi T, Nakachi K, Trosko JE, Sugihara K, Kotake Y, Ohta S. Modulation of connexin 43 in rotenone-induced model of Parkinson's disease. Neuroscience. 160: 61-8. PMID 19232380 DOI: 10.1016/J.Neuroscience.2009.01.080  0.317
2009 Nakamura Y, Kominami A, Tsujimoto Y, Nakayama Y, Kitahashi T, Yoshimoto S, Kubo A, Watanabe S, Kageyama M, Yokoyama M, Kido Y, Kobayashi Y, Kuwahata M, Chang CC, Upham BL, ... Trosko JE, et al. Actin and Vimentin proteins with N-terminal deletion detected in tumor-bearing rat livers induced by intraportal-vein injection of Ha-ras-transfected rat liver cells. International Journal of Cancer. 124: 2512-9. PMID 19199359 DOI: 10.1002/Ijc.24229  0.353
2009 Upham BL, Trosko JE. Oxidative-dependent integration of signal transduction with intercellular gap junctional communication in the control of gene expression. Antioxidants & Redox Signaling. 11: 297-307. PMID 18834329 DOI: 10.1089/Ars.2008.2146  0.344
2008 Trosko JE. Human adult stem cells as the target cells for the initiation of carcinogenesis and for the generation of "cancer stem cells". International Journal of Stem Cells. 1: 8-26. PMID 24855504 DOI: 10.15283/Ijsc.2008.1.1.8  0.394
2008 Nakamura Y, Nakayama Y, Ando H, Tanaka A, Matsuo T, Okamoto S, Upham BL, Chang CC, Trosko JE, Park EY, Sato K. 3-Methylthiopropionic acid ethyl ester, isolated from Katsura-uri (Japanese pickling melon, Cucumis melo var. conomon), enhanced differentiation in human colon cancer cells. Journal of Agricultural and Food Chemistry. 56: 2977-84. PMID 18426216 DOI: 10.1021/Jf072898I  0.326
2008 Trosko JE. Commentary: "re-programming or selecting adult stem cells?". Stem Cell Reviews. 4: 81-8. PMID 18425605 DOI: 10.1007/S12015-008-9017-1  0.362
2008 Upham BL, Bláha L, Babica P, Park JS, Sovadinova I, Pudrith C, Rummel AM, Weis LM, Sai K, Tithof PK, Guzvi? M, Vondrácek J, Machala M, Trosko JE. Tumor promoting properties of a cigarette smoke prevalent polycyclic aromatic hydrocarbon as indicated by the inhibition of gap junctional intercellular communication via phosphatidylcholine-specific phospholipase C. Cancer Science. 99: 696-705. PMID 18377422 DOI: 10.1111/J.1349-7006.2008.00752.X  0.335
2008 Umannová L, Neca J, Andrysík Z, Vondrácek J, Upham BL, Trosko JE, Hofmanová J, Kozubík A, Machala M. Non-dioxin-like polychlorinated biphenyls induce a release of arachidonic acid in liver epithelial cells: a partial role of cytosolic phospholipase A(2) and extracellular signal-regulated kinases 1/2 signalling. Toxicology. 247: 55-60. PMID 18367304 DOI: 10.1016/J.Tox.2008.02.002  0.37
2008 Hirabayashi Y, Yoon B, Tsuboi I, Huo Y, Kodama Y, Kanno J, Ott T, Trosko JE, Inoue T. The Cell Cycle in Hematopoietic Stem Cells, Lin−/C-kit+/Sca1+ Fraction, Is Regulated by Connexin 32, Specifically Expressed in the Stem Cell Compartment Blood. 112: 4775-4775. DOI: 10.1182/Blood.V112.11.4775.4775  0.419
2007 Webster JD, Yuzbasiyan-Gurkan V, Trosko JE, Chang CC, Kiupel M. Expression of the embryonic transcription factor Oct4 in canine neoplasms: a potential marker for stem cell subpopulations in neoplasia. Veterinary Pathology. 44: 893-900. PMID 18039902 DOI: 10.1354/Vp.44-6-893  0.443
2007 Trosko JE. Gap junctional intercellular communication as a biological "Rosetta stone" in understanding, in a systems biological manner, stem cell behavior, mechanisms of epigenetic toxicology, chemoprevention and chemotherapy. The Journal of Membrane Biology. 218: 93-100. PMID 17960321 DOI: 10.1007/S00232-007-9072-6  0.436
2007 Vondrácek J, Svihálková-Sindlerová L, Pencíková K, Marvanová S, Krcmár P, Ciganek M, Neca J, Trosko JE, Upham B, Kozubík A, Machala M. Concentrations of methylated naphthalenes, anthracenes, and phenanthrenes occurring in Czech river sediments and their effects on toxic events associated with carcinogenesis in rat liver cell lines. Environmental Toxicology and Chemistry / Setac. 26: 2308-16. PMID 17941746 DOI: 10.1897/07-161R.1  0.412
2007 Hirabayashi Y, Yoon BI, Tsuboi I, Huo Y, Kodama Y, Kanno J, Ott T, Trosko JE, Inoue T. Membrane channel connexin 32 maintains Lin(-)/c-kit(+) hematopoietic progenitor cell compartment: analysis of the cell cycle. The Journal of Membrane Biology. 217: 105-13. PMID 17629738 DOI: 10.1007/S00232-007-9042-Z  0.404
2007 Upham BL, Guzvi? M, Scott J, Carbone JM, Blaha L, Coe C, Li LL, Rummel AM, Trosko JE. Inhibition of gap junctional intercellular communication and activation of mitogen-activated protein kinase by tumor-promoting organic peroxides and protection by resveratrol. Nutrition and Cancer. 57: 38-47. PMID 17516861 DOI: 10.1080/01635580701268188  0.379
2007 Hirabayashi Y, Yoon BI, Tsuboi I, Huo Y, Kodama Y, Kanno J, Ott T, Trosko JE, Inoue T. Protective role of connexin 32 in steady-state hematopoiesis, regeneration state, and leukemogenesis. Experimental Biology and Medicine (Maywood, N.J.). 232: 700-12. PMID 17463168 DOI: 10.3181/00379727-232-2320700  0.323
2007 Tai MH, Upham BL, Olson LK, Tsao MS, Reed DN, Trosko JE. Cigarette smoke components inhibited intercellular communication and differentiation in human pancreatic ductal epithelial cells. International Journal of Cancer. Journal International Du Cancer. 120: 1855-62. PMID 17266035 DOI: 10.1002/Ijc.22530  0.394
2007 Hirabayashi Y, Yoon B, Tsuboi I, Huo Y, Kodama Y, Kanno J, Ott T, Trosko JE, Inoue T. Protective Role of Connexin 32 in Experimental Leukemogenesis. Blood. 110: 2239-2239. DOI: 10.1182/Blood.V110.11.2239.2239  0.357
2006 Trosko JE. From adult stem cells to cancer stem cells: Oct-4 Gene, cell-cell communication, and hormones during tumor promotion. Annals of the New York Academy of Sciences. 1089: 36-58. PMID 17261754 DOI: 10.1196/Annals.1386.018  0.453
2006 De Flora S, Scarfì S, Izzotti A, D'Agostini F, Chang CC, Bagnasco M, De Flora A, Trosko JE. Induction by 7,12-dimethylbenz(a)anthracene of molecular and biochemical alterations in transformed human mammary epithelial stem cells, and protection by N-acetylcysteine. International Journal of Oncology. 29: 521-9. PMID 16865267 DOI: 10.3892/Ijo.29.3.521  0.454
2006 Trosko JE. Dietary modulation of the multistage, multimechanisms of human carcinogenesis: effects on initiated stem cells and cell-cell communication. Nutrition and Cancer. 54: 102-10. PMID 16800778 DOI: 10.1207/S15327914Nc5401_12  0.428
2006 Trosko JE, Tai MH. Adult stem cell theory of the multi-stage, multi-mechanism theory of carcinogenesis: role of inflammation on the promotion of initiated stem cells Contributions to Microbiology.. 13: 45-65. PMID 16627958 DOI: 10.1159/000092965  0.417
2006 Trosko JE. The role of stem cells and gap junctions as targets for cancer chemoprevention and chemotherapy. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. S326-31. PMID 16507402 DOI: 10.1016/S0753-3322(05)80065-4  0.453
2006 Nishikawa A, Sai K, Okazaki K, Son HY, Kanki K, Nakajima M, Kinae N, Nohmi T, Trosko JE, Inoue T, Hirose M. MX, a by-product of water chlorination, lacks in vivo genotoxicity in gpt delta mice but inhibits gap junctional intercellular communication in rat WB cells. Environmental and Molecular Mutagenesis. 47: 48-55. PMID 16106442 DOI: 10.1002/Em.20167  0.393
2005 Ogawa T, Hayashi T, Tokunou M, Nakachi K, Trosko JE, Chang CC, Yorioka N. Suberoylanilide hydroxamic acid enhances gap junctional intercellular communication via acetylation of histone containing connexin 43 gene locus. Cancer Research. 65: 9771-8. PMID 16266998 DOI: 10.1158/0008-5472.Can-05-0227  0.419
2005 Trosko JE, Chang CC, Upham BL, Tai MH. The role of human adult stem cells and cell-cell communication in cancer chemoprevention and chemotherapy strategies. Mutation Research. 591: 187-97. PMID 16084532 DOI: 10.1016/J.Mrfmmm.2005.01.034  0.469
2005 Caruso RL, Upham BL, Harris C, Trosko JE. Biphasic lindane-induced oxidation of glutathione and inhibition of gap junctions in myometrial cells. Toxicological Sciences : An Official Journal of the Society of Toxicology. 86: 417-26. PMID 15901910 DOI: 10.1093/Toxsci/Kfi208  0.367
2005 Nakamura Y, Yoshikawa N, Hiroki I, Sato K, Ohtsuki K, Chang CC, Upham BL, Trosko JE. Beta-sitosterol from psyllium seed husk (Plantago ovata Forsk) restores gap junctional intercellular communication in Ha-ras transfected rat liver cells. Nutrition and Cancer. 51: 218-25. PMID 15860444 DOI: 10.1207/S15327914Nc5102_12  0.337
2005 Trosko JE, Chang CC, Upham BL, Tai MH. Low-dose ionizing radiation: induction of differential intracellular signalling possibly affecting intercellular communication. Radiation and Environmental Biophysics. 44: 3-9. PMID 15821925 DOI: 10.1007/S00411-005-0269-8  0.366
2005 Luster-Teasley SL, Ganey PE, DiOrio M, Ward JS, Maleczka RE, Trosko JE, Masten SJ. Effect of byproducts from the ozonation of pyrene: biphenyl-2,2',6,6'-tetracarbaldehyde and biphenyl-2,2',6,6'-tetracarboxylic acid on gap junction intercellular communication and neutrophil function. Environmental Toxicology and Chemistry / Setac. 24: 733-40. PMID 15786580 DOI: 10.1897/04-679.1  0.415
2005 Trosko JE, Upham BL. The emperor wears no clothes in the field of carcinogen risk assessment: ignored concepts in cancer risk assessment. Mutagenesis. 20: 81-92. PMID 15784692 DOI: 10.1093/Mutage/Gei017  0.353
2005 Loch-Caruso R, Upham BL, Harris C, Trosko JE. Divergent roles for glutathione in lindane-induced acute and delayed-onset inhibition of rat myometrial gap junctions. Toxicological Sciences : An Official Journal of the Society of Toxicology. 85: 694-702. PMID 15716478 DOI: 10.1093/Toxsci/Kfi123  0.365
2005 Nakamura Y, Chang CC, Mori T, Sato K, Ohtsuki K, Upham BL, Trosko JE. Augmentation of differentiation and gap junction function by kaempferol in partially differentiated colon cancer cells. Carcinogenesis. 26: 665-71. PMID 15618237 DOI: 10.1093/Carcin/Bgi003  0.432
2005 Tai MH, Chang CC, Kiupel M, Webster JD, Olson LK, Trosko JE. Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. Carcinogenesis. 26: 495-502. PMID 15513931 DOI: 10.1093/Carcin/Bgh321  0.43
2005 Trosko JE. The role of stem cells and cell–cell communication in radiation carcinogenesis: ignored concepts British Journal of Radiology. 132-138. DOI: 10.1259/Bjr/75133009  0.302
2005 Tai MH, Chang CC, Kiupel M, Webster JD, Olson LK, Trosko JE. Errarum: Oct4 expression in adult stem cells: Evidence in support of the stem cell theory of carcinogenesis (Carcinogenesis (2005) Vol. 26 (495-502)) Carcinogenesis. 26: 1316. DOI: 10.1093/Carcin/Bgi109  0.347
2004 Trosko JE, Chang CC, Upham BL, Tai MH. Ignored hallmarks of carcinogenesis: stem cells and cell-cell communication. Annals of the New York Academy of Sciences. 1028: 192-201. PMID 15650245 DOI: 10.1196/Annals.1322.023  0.469
2004 Linning KD, Tai MH, Madhukar BV, Chang CC, Reed DN, Ferber S, Trosko JE, Olson LK. Redox-mediated enrichment of self-renewing adult human pancreatic cells that possess endocrine differentiation potential. Pancreas. 29: e64-76. PMID 15367896 DOI: 10.1097/00006676-200410000-00015  0.329
2004 Moggs JG, Goodman JI, Trosko JE, Roberts RA. Epigenetics and cancer: implications for drug discovery and safety assessment. Toxicology and Applied Pharmacology. 196: 422-30. PMID 15094313 DOI: 10.1016/J.Taap.2004.01.009  0.321
2004 Davila JC, Cezar GG, Thiede M, Strom S, Miki T, Trosko J. Use and application of stem cells in toxicology. Toxicological Sciences : An Official Journal of the Society of Toxicology. 79: 214-23. PMID 15014205 DOI: 10.1093/Toxsci/Kfh100  0.374
2004 Nakamura Y, Trosko JE, Chang CC, Upham BL. Psyllium extracts decreased neoplastic phenotypes induced by the Ha-Ras oncogene transfected into a rat liver oval cell line. Cancer Letters. 203: 13-24. PMID 14670613 DOI: 10.1016/J.Canlet.2003.08.022  0.394
2004 Park J, Noh D, Kim S, Kim S, Kong G, Chang C, Lee Y, Trosko JE, Kang K. Gene expression analysis in SV40-immortalized human breast luminal epithelial cells with stem cell characteristics using a cDNA microarray. International Journal of Oncology. 24: 1545-1558. DOI: 10.3892/Ijo.24.6.1545  0.388
2003 Machala M, Bláha L, Vondrácek J, Trosko JE, Scott J, Upham BL. Inhibition of gap junctional intercellular communication by noncoplanar polychlorinated biphenyls: inhibitory potencies and screening for potential mode(s) of action. Toxicological Sciences : An Official Journal of the Society of Toxicology. 76: 102-11. PMID 12915713 DOI: 10.1093/Toxsci/Kfg209  0.387
2003 Upham BL, Suzuki J, Chen G, Wang Y, McCabe LR, Chang CC, Krutovskikh VA, Yamasaki H, Trosko JE. Reduced gap junctional intercellular communication and altered biological effects in mouse osteoblast and rat liver oval cell lines transfected with dominant-negative connexin 43. Molecular Carcinogenesis. 37: 192-201. PMID 12891628 DOI: 10.1002/Mc.10137  0.442
2003 Satoh AY, Trosko JE, Masten SJ. Epigenetic toxicity of hydroxylated biphenyls and hydroxylated polychlorinated biphenyls on normal rat liver epithelial cells. Environmental Science & Technology. 37: 2727-33. PMID 12854712 DOI: 10.1021/Es021041T  0.413
2003 Trosko JE, Chang CC. Isolation and characterization of normal adult human epithelial pluripotent stem cells. Oncology Research. 13: 353-7. PMID 12725525 DOI: 10.3727/096504003108748366  0.397
2003 Holland MS, Tai MH, Trosko JE, Griffin LD, Stasko JA, Cheville NC, Holland RE. Isolation and differentiation of bovine mammary gland progenitor cell populations. American Journal of Veterinary Research. 64: 396-403. PMID 12693527 DOI: 10.2460/Ajvr.2003.64.396  0.443
2003 Upham BL, Koski TR, Rummel AM, Wilson MR, Horvath A, Trosko JE. Differential roles of 2, 6, and 8 carbon ceramides on the modulation of gap junctional communication and apoptosis during carcinogenesis. Cancer Letters. 191: 27-34. PMID 12609706 DOI: 10.1016/S0304-3835(02)00620-1  0.373
2003 Trosko JE. Human stem cells as targets for the aging and diseases of aging processes. Medical Hypotheses. 60: 439-47. PMID 12581626 DOI: 10.1016/S0306-9877(02)00446-2  0.392
2003 Trosko JE. The role of stem cells and gap junctional intercellular communication in carcinogenesis. Journal of Biochemistry and Molecular Biology. 36: 43-8. PMID 12542974 DOI: 10.5483/Bmbrep.2003.36.1.043  0.47
2003 Upham BL, Rummel AM, Carbone JM, Trosko JE, Ouyang Y, Crawford RB, Kaminski NE. Cannabinoids inhibit gap junctional intercellular communication and activate ERK in a rat liver epithelial cell line. International Journal of Cancer. Journal International Du Cancer. 104: 12-8. PMID 12532414 DOI: 10.1002/Ijc.10899  0.451
2003 Tai MH, Olson LK, Madhukar BV, Linning KD, Van Camp L, Tsao MS, Trosko JE. Characterization of gap junctional intercellular communication in immortalized human pancreatic ductal epithelial cells with stem cell characteristics. Pancreas. 26: e18-26. PMID 12499933 DOI: 10.1097/00006676-200301000-00025  0.472
2003 Trosko JE, Ruch RJ. Gap junctions as targets for cancer chemoprevention and chemotherapy. Current Drug Targets. 3: 465-82. PMID 12448698 DOI: 10.2174/1389450023347371  0.351
2002 Hu W, Jones PD, Upham BL, Trosko JE, Lau C, Giesy JP. Inhibition of gap junctional intercellular communication by perfluorinated compounds in rat liver and dolphin kidney epithelial cell lines in vitro and Sprague-Dawley rats in vivo. Toxicological Sciences : An Official Journal of the Society of Toxicology. 68: 429-36. PMID 12151638 DOI: 10.1093/Toxsci/68.2.429  0.436
2002 Luster-Teasley SL, Yao JJ, Herner HH, Trosko JE, Masten SJ. Ozonation of chrysene: evaluation of byproduct mixtures and identification of toxic constituent. Environmental Science & Technology. 36: 869-76. PMID 11918009 DOI: 10.1021/Es011090Q  0.327
2002 Carruba G, Webber MM, Quader ST, Amoroso M, Cocciadiferro L, Saladino F, Trosko JE, Castagnetta LA. Regulation of cell-to-cell communication in non-tumorigenic and malignant human prostate epithelial cells. The Prostate. 50: 73-82. PMID 11816015 DOI: 10.1002/Pros.10034  0.411
2002 Trosko JE. From bacteria to humans: lessons learned from a reductionist's view of ultraviolet light-induced DNA lesions. Environmental and Molecular Mutagenesis. 38: 118-21. PMID 11746744 DOI: 10.1002/Em.1061  0.347
2002 Zhou H, Suzuki M, Randers-Pehrson G, Vannais D, Chen G, Trosko JE, Waldren CA, Hei TK. Radiation risk to low fluences of alpha particles may be greater than we thought. Proceedings of the National Academy of Sciences of the United States of America. 98: 14410-5. PMID 11734643 DOI: 10.1073/Pnas.251524798  0.351
2001 Horvath A, Upham BL, Ganev V, Trosko JE. Determination of the epigenetic effects of ochratoxin in a human kidney and a rat liver epithelial cell line Toxicon. 40: 273-282. PMID 11711124 DOI: 10.1016/S0041-0101(01)00219-7  0.456
2001 Saunders MM, You J, Trosko JE, Yamasaki H, Li Z, Donahue HJ, Jacobs CR. Gap junctions and fluid flow response in MC3T3-E1 cells American Journal of Physiology - Cell Physiology. 281. PMID 11698250 DOI: 10.1152/Ajpcell.2001.281.6.C1917  0.377
2001 Sai K, Kang KS, Hirose A, Hasegawa R, Trosko JE, Inoue T. Inhibition of apoptosis by pentachlorophenol in v-myc-transfected rat liver epithelial cells: relation to down-regulation of gap junctional intercellular communication. Cancer Letters. 173: 163-74. PMID 11597791 DOI: 10.1016/S0304-3835(01)00616-4  0.427
2001 Ogawa T, Hayashi T, Yorioka N, Kyoizumi S, Trosko JE. Hexamethylene bisacetamide protects peritoneal mesothelial cells from glucose. Kidney International. 60: 996-1008. PMID 11532094 DOI: 10.1046/J.1523-1755.2001.060003996.X  0.321
2001 Trosko JE, Chang CC. Mechanism of up-regulated gap junctional intercellular communication during chemoprevention and chemotherapy of cancer. Mutation Research. 219-29. PMID 11506816 DOI: 10.1016/S0027-5107(01)00181-6  0.456
2001 Masten SJ, Tian M, Upham BL, Trosko JE. Effect of selected pesticides and their ozonation by-products on gap junctional intercellular communication using rat liver epithelial cell lines Chemosphere. 44: 457-465. PMID 11459151 DOI: 10.1016/S0045-6535(00)00296-4  0.384
2001 Trosko JE. Commentary: is the concept of "tumor promotion" a useful paradigm? Molecular Carcinogenesis. 30: 131-7. PMID 11301473 DOI: 10.1002/Mc.1021  0.355
2001 Ruch RJ, Trosko JE. Gap-junction communication in chemical carcinogenesis. Drug Metabolism Reviews. 33: 117-24. PMID 11270660 DOI: 10.1081/Dmr-100000137  0.329
2001 Hayashi T, Trosko JE, Hamada K. Inhibition of gap junctional intercellular communication in rat liver epithelial cells with transforming RNA. Febs Letters. 491: 200-6. PMID 11240127 DOI: 10.1016/S0014-5793(01)02185-8  0.347
2001 Trosko JE, Chang CC. Modulation of cell-cell communication in the cause and chemoprevention/chemotherapy of cancer. Biofactors (Oxford, England). 12: 259-63. PMID 11216494 DOI: 10.1002/Biof.5520120139  0.476
2001 Chang CC, Sun W, Cruz A, Saitoh M, Tai MH, Trosko JE. A human breast epithelial cell type with stem cell characteristics as target cells for carcinogenesis. Radiation Research. 155: 201-207. PMID 11121235 DOI: 10.1667/0033-7587(2001)155[0201:Ahbect]2.0.Co;2  0.427
2001 Trosko JE, Chang CC. Role of stem cells and gap junctional intercellular communication in human carcinogenesis. Radiation Research. 155: 175-180. PMID 11121231 DOI: 10.1667/0033-7587(2001)155[0175:Roscag]2.0.Co;2  0.488
2000 Chen G, Upham BL, Sun W, Chang CC, Rothwell EJ, Chen KM, Yamasaki H, Trosko JE. Effect of electromagnetic field exposure on chemically induced differentiation of friend erythroleukemia cells. Environmental Health Perspectives. 108: 967-72. PMID 11049817 DOI: 10.1289/Ehp.00108967  0.457
2000 Sai K, Kanno J, Hasegawa R, Trosko JE, Inoue T. Prevention of the down-regulation of gap junctional intercellular communication by green tea in the liver of mice fed pentachlorophenol. Carcinogenesis. 21: 1671-6. PMID 10964098 DOI: 10.1093/Carcin/21.9.1671  0.377
2000 DeoCampo ND, Wilson MR, Trosko JE. Cooperation of bcl-2 and myc in the neoplastic transformation of normal rat liver epithelial cells is related to the down-regulation of gap junction-mediated intercellular communication. Carcinogenesis. 21: 1501-6. PMID 10910950 DOI: 10.1093/Carcin/21.5.501  0.787
2000 Trosko JE. Human health consequences of environmentally-modulated gene expression: potential roles of ELF-EMF induced epigenetic versus mutagenic mechanisms of disease. Bioelectromagnetics. 21: 402-6. PMID 10899776 DOI: 10.1002/1521-186X(200007)21:5<402::Aid-Bem9>3.0.Co;2-N  0.397
2000 Na HK, Wilson MR, Kang KS, Chang CC, Grunberger D, Trosko JE. Restoration of gap junctional intercellular communication by caffeic acid phenethyl ester (CAPE) in a ras-transformed rat liver epithelial cell line. Cancer Letters. 157: 31-8. PMID 10893439 DOI: 10.1016/S0304-3835(00)00470-5  0.428
2000 Trosko JE. Cloning of human stem cells: some broad scientific and philosophical issues. The Journal of Laboratory and Clinical Medicine. 135: 432-6. PMID 10850641 DOI: 10.1067/Mlc.2000.106803  0.361
2000 Suzuki J, Na HK, Upham BL, Chang CC, Trosko JE. Lambda-carrageenan-induced inhibition of gap-junctional intercellular communication in rat liver epithelial cells. Nutrition and Cancer. 36: 122-8. PMID 10798224 DOI: 10.1207/S15327914Nc3601_16  0.472
2000 Kang KS, Kang BC, Lee BJ, Che JH, Li GX, Trosko JE, Lee YS. Preventive effect of epicatechin and ginsenoside Rb(2) on the inhibition of gap junctional intercellular communication by TPA and H(2)O(2). Cancer Letters. 152: 97-106. PMID 10754211 DOI: 10.1016/S0304-3835(99)00438-3  0.392
2000 Trosko JE, Chang CC, Wilson MR, Upham B, Hayashi T, Wade M. Gap junctions and the regulation of cellular functions of stem cells during development and differentiation. Methods (San Diego, Calif.). 20: 245-64. PMID 10671317 DOI: 10.1006/Meth.1999.0941  0.415
2000 Dowling-Warriner CV, Trosko JE. Induction of gap junctional intercellular communication, connexin43 expression, and subsequent differentiation in human fetal neuronal cells by stimulation of the cyclic AMP pathway. Neuroscience. 95: 859-68. PMID 10670453 DOI: 10.1016/S0306-4522(99)00411-X  0.446
2000 Wilson MR, Close TW, Trosko JE. Cell population dynamics (apoptosis, mitosis, and cell-cell communication) during disruption of homeostasis. Experimental Cell Research. 254: 257-68. PMID 10640424 DOI: 10.1006/Excr.1999.4771  0.449
1999 Kamendulis LM, Jiang J, Zhang H, deFeijter-Rupp H, Trosko JE, Klaunig JE. The effect of acrylonitrile on gap junctional intercellular communication in rat astrocytes. Cell Biology and Toxicology. 15: 173-83. PMID 10580550 DOI: 10.1023/A:1007685504941  0.398
1999 Rummel AM, Trosko JE, Wilson MR, Upham BL. Polycyclic aromatic hydrocarbons with bay-like regions inhibited gap junctional intercellular communication and stimulated MAPK activity Toxicological Sciences. 49: 232-240. PMID 10416268 DOI: 10.1093/Toxsci/49.2.232  0.391
1999 Carruba G, Webber MM, Bello-Deocampo D, Amodio R, Notarbartolo M, Deocampo ND, Trosko JE, Castagnetta LA. Laser scanning analysis of cell-cell communication in cultured human prostate tumor cells. Analytical and Quantitative Cytology and Histology / the International Academy of Cytology [and] American Society of Cytology. 21: 54-8. PMID 10068776  0.776
1999 Trosko JE, Chang CC, Upham B, Wilson M. Epigenetic toxicology as toxicant-induced changes in intracellular signalling leading to altered gap junctional intercellular communication. Toxicology Letters. 71-8. PMID 10022235 DOI: 10.1016/S0378-4274(98)00288-4  0.436
1999 Ghoshal S, Weber WJ, Rummel AM, Trosko JE, Upham BL. Epigenetic toxicity of a mixture of polycyclic aromatic hydrocarbons on gap junctional intercellular communication before and after biodegradation Environmental Science and Technology. 33: 1044-1050. DOI: 10.1021/Es9809511  0.336
1998 Upham BL, Deocampo ND, Wurl B, Trosko JE. Inhibition of gap junctional intercellular communication by perfluorinated fatty acids is dependent on the chain length of the fluorinated tail. International Journal of Cancer. 78: 491-5. PMID 9797139 DOI: 10.1002/(Sici)1097-0215(19981109)78:4<491::Aid-Ijc16>3.0.Co;2-9  0.764
1998 Sai K, Upham BL, Kang KS, Hasegawa R, Inoue T, Trosko JE. Inhibitory effect of pentachlorophenol on gap junctional intercellular communication in rat liver epithelial cells in vitro. Cancer Letters. 130: 9-17. PMID 9751251 DOI: 10.1016/S0304-3835(98)00082-2  0.417
1998 Upham BL, Weis LM, Trosko JE. Modulated gap junctional intercellular communication as a biomarker of PAH epigenetic toxicity: structure-function relationship. Environmental Health Perspectives. 975-81. PMID 9703481 DOI: 10.1289/Ehp.98106S4975  0.443
1998 Hayashi T, Nomata K, Chang CC, Ruch RJ, Trosko JE. Cooperative effects of v-myc and c-Ha-ras oncogenes on gap junctional intercellular communication and tumorigenicity in rat liver epithelial cells. Cancer Letters. 128: 145-54. PMID 9683275 DOI: 10.1016/S0304-3835(98)00060-3  0.387
1998 Rae RS, Mehta PP, Chang CC, Trosko JE, Ruch RJ. Neoplastic phenotype of gap-junctional intercellular communication- deficient WB rat liver epithelial cells and its reversal by forced expression of connexin 32 Molecular Carcinogenesis. 22: 120-127. PMID 9655256 DOI: 10.1002/(Sici)1098-2744(199806)22:2<120::Aid-Mc7>3.0.Co;2-Q  0.447
1998 De Feijter-Rupp HL, Hayashi T, Kalimi GH, Edwards P, Redpath JL, Chang CC, Stanbridge EJ, Trosko JE. Restored gap junctional communication in non-tumorigenic HeLa-normal human fibroblast hybrids Carcinogenesis. 19: 747-754. PMID 9635859 DOI: 10.1093/Carcin/19.5.747  0.423
1998 Kang KS, Sun W, Nomata K, Morita I, Cruz A, Liu CJ, Trosko JE, Chang CC. Involvement of tyrosine phosphorylation of p185(c-erbB2/neu) in tumorigenicity induced by X-rays and the neu oncogene in human breast epithelial cells. Molecular Carcinogenesis. 21: 225-33. PMID 9585252 DOI: 10.1002/(Sici)1098-2744(199804)21:4<225::Aid-Mc1>3.0.Co;2-J  0.408
1998 Trosko JE. Hierarchical and cybernetic nature of biologic systems and their relevance to homeostatic adaptation to low-level exposures to oxidative stress-inducing agents. Environmental Health Perspectives. 331-9. PMID 9539027 DOI: 10.1289/Ehp.98106S1331  0.398
1998 Trosko JE, Ruch RJ. Cell-cell communication in carcinogenesis. Frontiers in Bioscience : a Journal and Virtual Library. 3: d208-36. PMID 9458335 DOI: 10.2741/A275  0.486
1998 Weis LM, Rummel AM, Masten SJ, Trosko JE, Upham BL. Bay or baylike regions of polycyclic aromatic hydrocarbons were potent inhibitors of gap junctional intercellular communication Environmental Health Perspectives. 106: 17-22. PMID 9417772 DOI: 10.1289/Ehp.9810617  0.38
1998 Trosko JE, Inoue T. Oxidative stress, signal transduction, and intercellular communication in radiation carcinogenesis. Stem Cells (Dayton, Ohio). 59-67. PMID 9368287 DOI: 10.1002/Stem.5530150710  0.413
1998 Sai K, Upham B, Kang K, Hasegawa R, Inoue T, Trosko J. Inhibitory effect of pentachlorophenol on gap junctional intercellular communication in rat liver epithelial cells in vitro Toxicology Letters. 95: 181. DOI: 10.1016/S0378-4274(98)80723-6  0.305
1998 Trosko J. Epigenetic toxicology as toxicant-induced changes in intracellular signalling leading to altered gap junctional communication Toxicology Letters. 95: 4-5. DOI: 10.1016/S0378-4274(98)80019-2  0.324
1997 Kang KS, Morita I, Cruz A, Jeon YJ, Trosko JE, Chang CC. Expression of estrogen receptors in a normal human breast epithelial cell type with luminal and stem cell characteristics and its neoplastically transformed cell lines. Carcinogenesis. 18: 251-7. PMID 9054615 DOI: 10.1093/Carcin/18.2.251  0.362
1997 Upham BL, Kang KS, Cho HY, Trosko JE. Hydrogen peroxide inhibits gap junctional intercellular communication in glutathione sufficient but not glutathione deficient cells Carcinogenesis. 18: 37-42. PMID 9054587 DOI: 10.1093/Carcin/18.1.37  0.458
1997 Hayashi T, Matesic DF, Nomata K, Kang KS, Chang CC, Trosko JE. Stimulation of cell proliferation and inhibition of gap junctional intercellular communication by linoleic acid. Cancer Letters. 112: 103-11. PMID 9029175 DOI: 10.1016/S0304-3835(96)04553-3  0.433
1997 Matesic DF, Hayashi T, Trosko JE, Germak JA. Upregulation of gap junctional intercellular communication in immortalized gonadotropin-releasing hormone neurons by stimulation of the cyclic AMP pathway. Neuroendocrinology. 64: 286-97. PMID 8895858 DOI: 10.1159/000127130  0.406
1997 Kang KS, Wilson MR, Hayashi T, Chang CC, Trosko JE. Inhibition of gap junctional intercellular communication in normal human breast epithelial cells after treatment with pesticides, PCBs, and PBBs, alone or in mixtures. Environmental Health Perspectives. 104: 192-200. PMID 8820588 DOI: 10.1289/Ehp.96104192  0.409
1997 Upham BL, Boddy B, Xing X, Trosko JE, Masten SJ. Non-genotoxic effects of selected pesticides and their disinfection by-products on gap junctional intercellular communication Ozone: Science and Engineering. 19: 351-369. DOI: 10.1080/01919519708547298  0.363
1996 Madhukar BV, de Feijter-Rupp HL, Trosko JE. Pulse treatment with the tumor promoter TPA delays the onset of desensitization response and prolongs the inhibitory effect on gap junctional intercellular communication of a rat liver epithelial cell line WB F-344. Cancer Letters. 106: 117-23. PMID 8827055 DOI: 10.1016/0304-3835(96)04315-7  0.385
1996 de Feijter AW, Matesic DF, Ruch RJ, Guan X, Chang CC, Trosko JE. Localization and function of the connexin 43 gap-junction protein in normal and various oncogene-expressing rat liver epithelial cells. Molecular Carcinogenesis. 16: 203-12. PMID 8784463 DOI: 10.1002/(Sici)1098-2744(199608)16:4<203::Aid-Mc4>3.0.Co;2-G  0.421
1996 Nomata K, Kang KS, Hayashi T, Matesic D, Lockwood L, Chang CC, Trosko JE. Inhibition of gap junctional intercellular communication in heptachlor- and heptachlor epoxide-treated normal human breast epithelial cells. Cell Biology and Toxicology. 12: 69-78. PMID 8738476 DOI: 10.1007/Bf00143357  0.407
1996 Hofer A, Sáez JC, Chang CC, Trosko JE, Spray DC, Dermietzel R. C-erbB2/neu transfection induces gap junctional communication incompetence in glial cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 4311-21. PMID 8699242 DOI: 10.1523/Jneurosci.16-14-04311.1996  0.42
1996 Trosko JE. Role of low-level ionizing radiation in multi-step carcinogenic process. Health Physics. 70: 812-22. PMID 8635905 DOI: 10.1097/00004032-199606000-00005  0.352
1996 Upham BL, Weis LM, Rummel AM, Masten SJ, Trosko JE. The effects of anthracene and methylated anthracenes on gap junctional intercellular communication in rat liver epithelial cells Toxicological Sciences. 34: 260-264. DOI: 10.1093/Toxsci/34.2.260  0.36
1995 Jou YS, Layhe B, Matesic DF, Chang CC, de Feijter AW, Lockwood L, Welsch CW, Klaunig JE, Trosko JE. Inhibition of gap junctional intercellular communication and malignant transformation of rat liver epithelial cells by neu oncogene. Carcinogenesis. 16: 311-7. PMID 7859363 DOI: 10.1093/Carcin/16.2.311  0.447
1995 Esinduy CB, Chang CC, Trosko JE, Ruch RJ. In vitro growth inhibition of neoplastically transformed cells by non-transformed cells: requirement for gap junctional intercellular communication. Carcinogenesis. 16: 915-21. PMID 7728974 DOI: 10.1093/Carcin/16.4.915  0.441
1995 Upham BL, Jehng Jyun Yao, Trosko JE, Masten SJ. Determination of the efficacy of ozone treatment systems using a gap junction intercellular communication bioassay Environmental Science and Technology. 29: 2923-2928. DOI: 10.1021/Es00012A006  0.314
1995 Dermietzel R, Hofer A, Rollmann A, Müller CM, Trosko JE. Functional plasticity and cell specific expression of connexins in normal and pathological glial tissues Progress in Cell Research. 4: 235-237. DOI: 10.1016/B978-0-444-81929-1.50048-4  0.32
1994 Ruch RJ, Bonney WJ, Sigler K, Guan X, Matesic D, Schafer LD, Dupont E, Trosko JE. Loss of gap junctions from ddt-treated rat liver epithelial cells Carcinogenesis. 15: 301-306. PMID 8313522 DOI: 10.1093/Carcin/15.2.301  0.437
1994 Matesic DF, Rupp HL, Bonney WJ, Ruch RJ, Trosko JE. Changes in gap-junction permeability, phosphorylation, and number mediated by phorbol ester and non-phorbol-ester tumor promoters in rat liver epithelial cells. Molecular Carcinogenesis. 10: 226-36. PMID 8068183 DOI: 10.1002/Mc.2940100407  0.357
1994 Trosko JE, Chang CC, Madhukar BV. The role of modulated gap junctional intercellular communication in epigenetic toxicology. Risk Analysis : An Official Publication of the Society For Risk Analysis. 14: 303-12. PMID 8029502 DOI: 10.1111/J.1539-6924.1994.Tb00245.X  0.431
1994 Trosko JE, Goodman JI. Intercellular communication may facilitate apoptosis: implications for tumor promotion. Molecular Carcinogenesis. 11: 8-12. PMID 7916991 DOI: 10.1002/Mc.2940110103  0.354
1994 Upham BL, Masten SJ, Lockwood BR, Trosko JE. Nongenotoxic effects of polycyclic aromatic hydrocarbons and their oxygenation by-products on the intercellular communication of rat liver epithelial cells. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 23: 470-5. PMID 7835547 DOI: 10.1006/Faat.1994.1129  0.405
1993 Trosko JE, Madhukar BV, Chang CC. Endogenous and exogenous modulation of gap junctional intercellular communication: toxicological and pharmacological implications. Life Sciences. 53: 1-19. PMID 8515679 DOI: 10.1016/0024-3205(93)90606-4  0.429
1993 Ruch RJ, Madhukar BV, Trosko JE, Klaunig JE. Reversal of ras-induced inhibition of gap-junctional intercellular communication, transformation, and tumorigenesis by lovastatin. Molecular Carcinogenesis. 7: 50-9. PMID 8435109 DOI: 10.1002/Mc.2940070109  0.366
1993 Chaudhuri R, Sigler K, Dupont E, Trosko JE, Malkinson AM, Ruch RJ. Gap junctional intercellular communication in mouse lung epithelial cell lines: effects of cell transformation and tumor promoters. Cancer Letters. 71: 11-8. PMID 8395972 DOI: 10.1016/0304-3835(93)90090-V  0.432
1993 Jou YS, Matesic D, Dupont E, Lu SC, Rupp HL, Madhukar BV, Oh SY, Trosko JE, Chang CC. Restoration of gap-junctional intercellular communication in a communication-deficient rat liver cell mutant by transfection with connexin 43 cDNA. Molecular Carcinogenesis. 8: 234-44. PMID 8280372 DOI: 10.1002/Mc.2940080406  0.386
1992 Kalimi GH, Hampton LL, Trosko JE, Thorgeirsson SS, Huggett AC. Homologous and heterologous gap-junctional intercellular communication in v-raf-, v-myc-, and v-raf/v-myc-transduced rat liver epithelial cell lines. Molecular Carcinogenesis. 5: 301-10. PMID 1379816 DOI: 10.1002/Mc.2940050411  0.416
1992 de Feijter AW, Trosko JE, Krizman DB, Lebovitz RM, Lieberman MW. Correlation of increased levels of Ha-ras T24 protein with extent of loss of gap junction function in rat liver epithelial cells. Molecular Carcinogenesis. 5: 205-12. PMID 1375030 DOI: 10.1002/Mc.2940050307  0.347
1991 Trosko JE, Chang CC, Madhukar BV, Klaunig JE. Chemical, oncogene and growth factor inhibition gap junctional intercellular communication: an integrative hypothesis of carcinogenesis. Pathobiology : Journal of Immunopathology, Molecular and Cellular Biology. 58: 265-78. PMID 2076190 DOI: 10.1159/000163596  0.446
1991 Kuslikis BI, Trosko JE, Braselton WE. Mutagenicity and effect on gap-junctional intercellular communication of 4,4'-methylenebis(2-chloroaniline) and its oxidized metabolites. Mutagenesis. 6: 19-24. PMID 2038268 DOI: 10.1093/Mutage/6.1.19  0.363
1991 Loch-Caruso R, Corcos IA, Trosko JE. Inhibition of metabolic coupling by metals. Journal of Toxicology and Environmental Health. 32: 33-48. PMID 1987361 DOI: 10.1080/15287399109531463  0.361
1991 Hasler CM, Trosko JE, Bennink MR. Incorporation of n-3 fatty acids into WB-F344 cell phospholipids inhibits gap junctional intercellular communication Lipids. 26: 788-792. PMID 1839047 DOI: 10.1007/Bf02536159  0.327
1991 Hasler CM, Bennink MR, Trosko JE. Inhibition of gap junction-mediated intercellular communication by α-linolenate American Journal of Physiology - Cell Physiology. 261. PMID 1677533 DOI: 10.1152/Ajpcell.1991.261.1.C161  0.344
1990 Dube DK, Loch-Caruso R, Trosko JE, Chakravarty I, Ghosh A, Loeb LA. Assessment of the carcinogenic potential of a proposed food coloring additive, laccaic acid, using short-term assays. Cell Biology and Toxicology. 1: 111-25. PMID 6401125 DOI: 10.1007/Bf00125569  0.311
1990 Chen TH, Kavanagh TJ, Chang CC, Trosko JE. Inhibition of metabolic cooperation in Chinese hamster V79 cells by various organic solvents and simple compounds. Cell Biology and Toxicology. 1: 155-71. PMID 6400921 DOI: 10.1007/Bf00125572  0.437
1990 Trosko JE, Chang CC. Stem cell theory of carcinogenesis. Toxicology Letters. 49: 283-95. PMID 2690407 DOI: 10.1016/0378-4274(89)90038-6  0.348
1990 Mori T, Matsunaga T, Chang CC, Trosko JE, Nikaido O. In situ (6-4)photoproduct determination by laser cytometry and autoradiography. Mutation Research. 236: 99-105. PMID 2366799 DOI: 10.1016/0921-8777(90)90037-6  0.34
1990 Ye YX, Bombick D, Hirst K, Zhang GX, Chang CC, Trosko JE, Akera T. The modulation of gap junctional communication by gossypol in various mammalian cell lines in vitro. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 14: 817-32. PMID 2361580 DOI: 10.1016/0272-0590(90)90306-5  0.461
1990 De Feijter AW, Ray JS, Weghorst CM, Klaunig JE, Goodman JI, Chang CC, Ruch RJ, Trosko JE. Infection of rat liver epithelial cells with v-Ha-ras: Correlation between oncogene expression, gap junctional communication, and tumorigenicity Molecular Carcinogenesis. 3: 54-67. PMID 2346586 DOI: 10.1002/Mc.2940030203  0.351
1990 Hasler CM, Frick MA, Bennink MR, Trosko JE. TPA-induced inhibition of gap junctional intercellular communication is not mediated through free radicals Toxicology and Applied Pharmacology. 103: 389-398. PMID 2339413 DOI: 10.1016/0041-008X(90)90312-I  0.393
1990 Li IC, Chang CC, Trosko JE. Thymidylate synthetase gene as a quantitative mutation marker in Chinese hamster cells. Mutation Research. 243: 233-9. PMID 2308599 DOI: 10.1016/0165-7992(90)90096-3  0.338
1990 Trosko JE, Chang CC, Madhukar BV. Modulation of Intercellular Communication during Radiation and Chemical Carcinogenesis Radiation Research. 123: 241. DOI: 10.2307/3577728  0.473
1990 Zhong-Xiang L, Chang CC, Trosko JE. Gap junctional intercellular communication (GJIC) in rat glioma cells--characterizations to detect inhibitors of metabolic cooperation. Science China-Chemistry. 33: 435-443. DOI: 10.1360/Yb1990-33-4-435  0.429
1989 Nicolson GL, Lichtner RB, Trosko JE. Cytoskeletal and junctional heterogeneity in mammary tumor cells and their possible significance in tumor progression. Advances in Experimental Medicine and Biology. 233: 21-6. PMID 3223382 DOI: 10.1007/978-1-4899-5037-6_4  0.321
1989 Aylsworth CF, Trosko JE, Chang CC, Benjamin K, Lockwood E. Synergistic inhibition of metabolic cooperation by oleic acid or 12-0-tetradecanoylphorbol-13-acetate and dichlorodiphenyltrichlorethane (DDT) in Chinese hamster V79 cells: implication of a role for protein kinase C in the regulation of gap junctional intercellular communication. Cell Biology and Toxicology. 5: 27-37. PMID 2920298 DOI: 10.1007/Bf00141062  0.447
1989 El-Fouly MH, Trosko JE, Chang CC, Warren ST. Potential role of the human Ha-ras oncogene in the inhibition of gap junctional intercellular communication Molecular Carcinogenesis. 2: 131-135. PMID 2675903 DOI: 10.1002/Mc.2940020305  0.623
1989 Mori T, Wani AA, D'Ambrosio SM, Chang CC, Trosko JE. In situ pyrimidine dimer determination by laser cytometry. Photochemistry and Photobiology. 49: 523-6. PMID 2657812 DOI: 10.1111/J.1751-1097.1989.Tb09205.X  0.332
1989 Madhukar BV, Oh SY, Chang CC, Wade M, Trosko JE. Altered regulation of intercellular communication by epidermal growth factor, transforming growth factor-beta and peptide hormones in normal human keratinocytes. Carcinogenesis. 10: 13-20. PMID 2463113 DOI: 10.1093/Carcin/10.1.13  0.353
1988 Nicolson GL, Dulski KM, Trosko JE. Loss of intercellular junctional communication correlates with metastatic potential in mammary adenocarcinoma cells. Proceedings of the National Academy of Sciences of the United States of America. 85: 473-6. PMID 3422438 DOI: 10.1073/Pnas.85.2.473  0.414
1988 Oh SY, Madhukar BV, Trosko JE. Inhibition of gap junctional blockage by palmitoyl carnitine and TMB-8 in a rat liver epithelial cell line. Carcinogenesis. 9: 135-9. PMID 3335038 DOI: 10.1093/Carcin/9.1.135  0.475
1988 Evans MG, Trosko JE. Concentration/response effect of 2,2', 4,4', 5,5'-hexabromobiphenyl on cell-cell communication in vitro: assessment by fluorescence redistribution after photobleaching ("FRAP"). Cell Biology and Toxicology. 4: 163-71. PMID 2852992 DOI: 10.1007/Bf00119243  0.489
1988 Chang CC, Jone C, Trosko JE, Peterson AR, Sevanian A. Effect of cholesterol epoxides on the inhibition of intercellular communication and on mutation induction in Chinese hamster V79 cells. Mutation Research. 206: 471-8. PMID 2849716 DOI: 10.1016/0165-1218(88)90056-0  0.356
1988 Evans MG, el-Fouly MH, Trosko JE, Sleight SD. Anchored cell analysis/sorting coupled with the scrape-loading/dye-transfer technique to quantify inhibition of gap-junctional intercellular communication in WB-F344 cells by 2,2',4,4',5,5'-hexabromobiphenyl. Journal of Toxicology and Environmental Health. 24: 261-71. PMID 2838643 DOI: 10.1080/15287398809531159  0.43
1988 Suter S, Trosko JE, el-Fouly MH, Lockwood LR, Koestner A. Dieldrin inhibition of gap junctional intercellular communication in rat glial cells as measured by the fluorescence photobleaching and scrape loading/dye transfer assays. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 9: 785-94. PMID 2446941 DOI: 10.1016/0272-0590(87)90185-0  0.421
1987 Trosko JE. Mechanisms of tumor promotion: possible role of inhibited intercellular communication. European Journal of Cancer & Clinical Oncology. 23: 599-601. PMID 3653183 DOI: 10.1016/0277-5379(87)90252-5  0.42
1987 Jongen WM, van der Leede BJ, Chang CC, Trosko JE. The transport of reactive intermediates in a co-cultivation system: the role of intercellular communication. Carcinogenesis. 8: 1239-43. PMID 3621464 DOI: 10.1016/0165-1161(88)90107-0  0.435
1987 Schindler M, Trosko JE, Wade MH. Fluorescence photobleaching assay of tumor promoter 12-O-tetradecanoylphorbol 13-acetate inhibition of cell-cell communication. Methods in Enzymology. 141: 439-47. PMID 3600363 DOI: 10.1016/0076-6879(87)41090-2  0.449
1987 Jone C, Trosko JE, Chang CC. Characterization of a rat liver epithelial cell line to detect inhibitors of metabolic cooperation. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 23: 214-20. PMID 3558255 DOI: 10.1007/BF02623582  0.383
1987 Jone C, Erickson L, Trosko JE, Chang CC. Effect of biological toxins on gap-junctional intercellular communication in Chinese hamster V79 cells. Cell Biology and Toxicology. 3: 1-15. PMID 3507245 DOI: 10.1007/Bf00117821  0.414
1987 Aylsworth CF, Welsch CW, Kabara JJ, Trosko JE. Effects of fatty acids on gap junctional communication: possible role in tumor promotion by dietary fat. Lipids. 22: 445-54. PMID 3302580 DOI: 10.1007/Bf02537277  0.375
1987 Kavanagh TJ, Chang CC, Trosko JE. Effect of various polybrominated biphenyls on cell-cell communication in cultured human teratocarcinoma cells Fundamental and Applied Toxicology. 8: 127-131. PMID 3030867 DOI: 10.1016/0272-0590(87)90108-4  0.486
1987 Gibson-D'Ambrosio RE, Samuel M, Chang CC, Trosko JE, D'Ambrosio SM. Characteristics of long-term human epithelial cell cultures derived from normal human fetal kidney. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 23: 279-87. PMID 2437097 DOI: 10.1007/Bf02623711  0.354
1987 el-Fouly MH, Trosko JE, Chang CC. Scrape-loading and dye transfer. A rapid and simple technique to study gap junctional intercellular communication. Experimental Cell Research. 168: 422-30. PMID 2433137 DOI: 10.1016/0014-4827(87)90014-0  0.422
1986 Wade MH, Trosko JE, Schindler M. A fluorescence photobleaching assay of gap junction-mediated communication between human cells. Science (New York, N.Y.). 232: 525-8. PMID 3961495 DOI: 10.1126/Science.3961495  0.44
1986 Lin ZX, Kavanagh T, Trosko JE, Chang CC. Inhibition of gap junctional intercellular communication in human teratocarcinoma cells by organochlorine pesticides. Toxicology and Applied Pharmacology. 83: 10-9. PMID 3952740 DOI: 10.1016/0041-008X(86)90318-2  0.492
1986 Loch-Caruso R, Trosko JE. Inhibited intercellular communication as a mechanistic link between teratogenesis and carcinogenesis. Critical Reviews in Toxicology. 16: 157-83. PMID 3910355 DOI: 10.3109/10408448509056269  0.466
1986 Trosko JE, Chang CC. Role of intercellular communication in modifying the consequences of mutations in somatic cells. Basic Life Sciences. 39: 439-56. PMID 3767847 DOI: 10.1007/978-1-4684-5182-5_39  0.311
1985 Trosko JE, Chang CC. Role of tumor promotion in affecting the multi-hit nature of carcinogenesis. Basic Life Sciences. 33: 261-84. PMID 4015584 DOI: 10.1007/978-1-4684-4970-9_15  0.396
1985 Jone C, Trosko JE, Aylsworth CF, Parker L, Chang CC. Further characterization of the in vitro assay for inhibitors of metabolic cooperation in the Chinese hamster V79 cell line. Carcinogenesis. 6: 361-6. PMID 3978751 DOI: 10.1093/Carcin/6.3.361  0.415
1985 Kavanagh TJ, Rubinstein C, Liu PL, Chang CC, Trosko JE, Sleight SD. Failure to induce mutations in Chinese hamster V79 cells and WB rat liver cells by the polybrominated biphenyls, Firemaster BP-6, 2,2',4,4',5,5'-hexabromobiphenyl, 3,3',4,4',5,5'-hexabromobiphenyl, and 3,3',4,4'-tetrabromobiphenyl. Toxicology and Applied Pharmacology. 79: 91-8. PMID 2996176 DOI: 10.1016/0041-008X(85)90371-0  0.396
1985 Chang CC, Trosko JE, Kung HJ, Bombick D, Matsumura F. Potential role of the src gene product in inhibition of gap-junctional communication in NIH/3T3 cells. Proceedings of the National Academy of Sciences of the United States of America. 82: 5360-4. PMID 2991919 DOI: 10.1073/Pnas.82.16.5360  0.408
1985 Jone CM, Erickson LM, Trosko JE, Netzloff ML, Chang CC. Inhibition of metabolic cooperation by the anticonvulsants, diphenylhydantoin and phenobarbital. Teratogenesis, Carcinogenesis, and Mutagenesis. 5: 379-91. PMID 2874624 DOI: 10.1002/Tcm.1770050602  0.446
1985 Loch-Caruso R, Trosko JE, Netzloff ML. 287 POTENTIAL ROLE OF INTERCELLULAR COMMUNICATION IN MORPHOGENESIS OF HYDRA REAGGREGATES Pediatric Research. 19: 158A-158A. DOI: 10.1203/00006450-198504000-00317  0.42
1984 Rubinstein C, Jone C, Trosko JE, Chang CC. Inhibition of intercellular communication in cultures of Chinese hamster V79 cells by 2,4-dichlorophenoxyacetic acid and 2,4,5-trichlorophenoxyacetic acid. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 4: 731-9. PMID 6510604 DOI: 10.1016/0272-0590(84)90094-0  0.399
1984 Loch-Caruso R, Trosko JE, Corcos IA. Interruption of cell-cell communication in Chinese hamster V79 cells by various alkyl glycol ethers: implications for teratogenicity. Environmental Health Perspectives. 57: 119-23. PMID 6499795 DOI: 10.1289/Ehp.8457119  0.404
1984 Liu PK, Chang CC, Trosko JE. Evidence for mutagenic repair in V79 cell mutant with aphidicolin-resistant DNA polymerase-alpha. Somatic Cell and Molecular Genetics. 10: 235-45. PMID 6426068 DOI: 10.1007/Bf01535246  0.307
1984 Aylsworth CF, Jone C, Trosko JE, Meites J, Welsch CW. Promotion of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis by high dietary fat in the rat: possible role of intercellular communication. Journal of the National Cancer Institute. 72: 637-45. PMID 6422115 DOI: 10.1093/Jnci/72.3.637  0.351
1984 Trosko JE, Chang CC, Medcalf A. Mechanisms of tumor promotion: potential role of intercellular communication. Cancer Investigation. 1: 511-26. PMID 6365277 DOI: 10.3109/07357908309020276  0.353
1983 Wade MH, Trosko JE. Enhanced survival and decreased mutation frequency after photoreactivation of UV damage in rat kangaroo cells. Mutation Research. 112: 231-43. PMID 6888409 DOI: 10.1016/0167-8817(83)90009-3  0.372
1983 Burczak JD, Moskal JR, Trosko JE, Fairley JL, Sweeley CC. Phorbol ester-associated changes in ganglioside metabolism. Experimental Cell Research. 147: 281-6. PMID 6578051 DOI: 10.1016/0014-4827(83)90210-0  0.376
1983 Trosko JE, Jone C, Chang CC. The role of tumor promoters on phenotypic alterations affecting intercellular communication and tumorigenesis. Annals of the New York Academy of Sciences. 407: 316-27. PMID 6349482 DOI: 10.1111/J.1749-6632.1983.Tb47837.X  0.362
1983 Jensen RK, Sleight SD, Aust SD, Goodman JI, Trosko JE. Hepatic tumor-promoting ability of 3,3',4,4',5,5'-hexabromobiphenyl: the interrelationship between toxicity, induction of hepatic microsomal drug metabolizing enzymes, and tumor-promoting ability. Toxicology and Applied Pharmacology. 71: 163-76. PMID 6314605 DOI: 10.1016/0041-008X(83)90333-2  0.305
1983 Madhukar BV, Yoneyama M, Matsumura F, Trosko JE, Tsushimoto G. Alteration of calcium transport by tumor promoters, 12-O-tetradecanoyl phorbol-13-acetate and p,p'-dichlorodiphenyltrichloroethane, in the Chinese hamster V79 fibroblast cell line. Cancer Letters. 18: 251-9. PMID 6303558 DOI: 10.1016/0304-3835(83)90233-1  0.374
1983 Tsushimoto G, Chang CC, Trosko JE, Matsumura F. Cytotoxic, mutagenic, and cell-cell communication inhibitory properties of DDT, lindane, and chlordane on Chinese hamster cells in vitro. Archives of Environmental Contamination and Toxicology. 12: 721-9. PMID 6197034 DOI: 10.1007/Bf01060757  0.485
1983 Trosko JE, Chang C. Potential Role of Intercellular Communication in the Rate-Limiting Step in Carcinogenesis Journal of the American College of Toxicology. 2: 5-22. DOI: 10.3109/10915818309140689  0.466
1982 Trosko JE, Jone C, Aylsworth C, Tsushimoto G. Elimination of metabolic cooperation is associated with the tumor promoters, oleic acid and anthralin. Carcinogenesis. 3: 1101-3. PMID 7139869 DOI: 10.1093/Carcin/3.9.1101  0.37
1982 Warren ST, Dolittle DJ, Chang Cc, Goodman JI, Trosko JE. Evaluation of the carcinogenic potential of 2,4-dinitrofluorobenzene and its implications regarding mutagenicity testing Carcinogenesis. 3: 139-145. PMID 7039854 DOI: 10.1093/Carcin/3.2.139  0.628
1982 Chang CC, Boezi JA, Warren ST, Sabourin CLK, Liu PK, Glatzer L, Trosko JE. Isolation and characterization of a UV-sensitive hypermutable aphidicolin-resistant Chinese hamster cell line Somatic Cell Genetics. 7: 235-253. PMID 6794164 DOI: 10.1007/Bf01567660  0.546
1982 Tsushimoto G, Trosko JE, Chang CC, Aust SD. Inhibition of metabolic cooperation in Chinese hamster V79 cells in culture by various polybrominated biphenyl (PBB) congeners. Carcinogenesis. 3: 181-5. PMID 6279328 DOI: 10.1093/Carcin/3.2.181  0.439
1982 Tsushimoto G, Trosko JE, Chang CC, Matsumura F. Inhibition of intercellular communication by chlordecone (kepone) and mirex in Chinese hamster v79 cells in vitro. Toxicology and Applied Pharmacology. 64: 550-6. PMID 6182642 DOI: 10.1016/0041-008X(82)90252-6  0.445
1982 Jensen RK, Sleight SD, Goodman JI, Aust SD, Trosko JE. Polybrominated biphenyls as promoters in experimental hepatocarcinogenesis in rats. Carcinogenesis. 3: 1183-6. PMID 6129071 DOI: 10.1093/Carcin/3.10.1183  0.303
1982 Trosko JE, Chang CC, Netzloff M. The role of inhibited cell-cell communication in teratogenesis. Teratogenesis, Carcinogenesis, and Mutagenesis. 2: 31-45. PMID 6122278 DOI: 10.1002/1520-6866(1990)2:1<31::Aid-Tcm1770020105>3.0.Co;2-2  0.447
1982 Trosko JE. Potential role of mutations and inhibited intercellular communication in the genesis of some chronic diseases Journal of Environmental Science and Health . Part a: Environmental Science and Engineering. 17: 605-608. DOI: 10.1080/10934528209375063  0.426
1981 Schultz RA, Trosko JE, Chang CC. Isolation and partial characterization of mutagen-sensitive and DNA repair mutants of Chinese hamster fibroblasts. Environmental Mutagenesis. 3: 53-64. PMID 7262053 DOI: 10.1002/Em.2860030106  0.325
1981 Warren ST, Yotti LP, Moskal JR, Chang CC, Trosko JE. Metabolic cooperation in CHO and V79 cells following treatment with a tumor promoter Experimental Cell Research. 131: 427-430. PMID 7202544 DOI: 10.1016/0014-4827(81)90250-0  0.634
1981 Warren ST, Schultz RA, Chang CC, Wade MH, Trosko JE. Elevated spontaneous mutation rate in Bloom syndrome fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 78: 3133-3137. PMID 6942420 DOI: 10.1073/Pnas.78.5.3133  0.524
1981 Chang CC, Castellazzi M, Trosko JE. Effect of temperature and exogenous dibutyryl c-AMP on the recovery of UV-induced ouabain-resistant Chinese hamster cells. Mutation Research. 91: 81-6. PMID 6259522 DOI: 10.1016/0165-7992(81)90076-2  0.314
1981 Trosko JE, Dawson B, Chang CC. PBB inhibits metabolic cooperation in Chinese hamster cells in vitro: its potential as a tumor promoter. Environmental Health Perspectives. 37: 179-82. PMID 6257504 DOI: 10.1289/Ehp.8137179  0.46
1981 Trosko JE, Chang C. The Role of Radiation and Chemicals in the Induction of Mutations and Epigenetic Changes during Carcinogenesis1 Advances in Radiation Biology. 9: 1-36. DOI: 10.1016/B978-0-12-035409-2.50006-0  0.336
1980 Trosko JE, Dawson B, Yotti LP, Chang CC. Saccharin may act as a tumour promoter by inhibiting metabolic cooperation between cells. Nature. 285: 109-10. PMID 7374758 DOI: 10.1038/285109A0  0.392
1980 Trosko JE, Schultz RS, Chang CC, Glover T. Ultraviolet light induction of diphtheria toxin-resistant mutations in normal and DNA repair-deficient human and Chinese hamster fibroblasts Basic Life Sciences. 15: 323-341. PMID 7213317 DOI: 10.1007/978-1-4684-3842-0_21  0.35
1980 Yotti LP, Glover TW, Trosko JE, Segal DJ. Comparative study of x-ray and UV induced cytotoxicity, DNA repair, and mutagenesis in Down's syndrome and normal fibroblasts. Pediatric Research. 14: 88-92. PMID 6444711 DOI: 10.1203/00006450-198002000-00003  0.316
1980 Trosko JE, Chang CC. Relationship between mutagenesis and carcinogenesis. Photochemistry and Photobiology. 28: 157-68. PMID 395546 DOI: 10.1111/J.1751-1097.1978.Tb07690.X  0.356
1979 Yotti LP, Chang CC, Trosko JE. Elimination of metabolic cooperation in Chinese hamster cells by a tumor promoter. Science (New York, N.Y.). 206: 1089-91. PMID 493994 DOI: 10.1126/Science.493994  0.439
1979 Glover TW, Chang CC, Trosko JE, Li SS. Ultraviolet light induction of diphtheria toxin-resistant mutants of normal and xeroderma pigmentosum human fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 76: 3982-6. PMID 291058 DOI: 10.1073/Pnas.76.8.3982  0.343
1978 Chang CC, D'Ambrosio SM, Schultz R, Trosko JE, Setlow RB. Modification of UV-induced mutation frequencies in Chinese hamster cells by dose fractionation, cycloheximide and caffeine treatments. Mutation Research. 52: 231-45. PMID 740008 DOI: 10.1016/0027-5107(78)90144-6  0.317
1978 Chang CC, Trosko JE, Akera T. Characterization of ultraviolet light-induced ouabain-resistant mutations in Chinese hamster cells. Mutation Research. 51: 85-98. PMID 149923 DOI: 10.1016/0027-5107(78)90011-8  0.345
1978 Trosko JE, Chang C. Chemical Modification Of Radiation-Induced Mutagenesis And Its Role In Carcinogenesis Dna Repair Mechanisms. 713-716. DOI: 10.1016/B978-0-12-322650-1.50138-7  0.334
1977 Chang CC, Philipps C, Trosko JE, Hart RW. Mutagenic and epigenetic influence of caffeine on the frequencies of UV-induced ouabain-resistant Chinese hamster cells. Mutation Research. 45: 125-36. PMID 917032 DOI: 10.1016/0027-5107(77)90050-1  0.301
1976 Goodman JI, Trosko JE, Yager JD. Studies on the mechanism of inhibition of 2-acetylaminofluorene toxicity by butylated hydroxytoluene. Chemico-Biological Interactions. 12: 171-82. PMID 1248061 DOI: 10.1016/0009-2797(76)90097-1  0.31
1976 Trosko JE, Chu EH. The role of DNA repair and somatic mutation in carcinogenesis. Advances in Cancer Research. 21: 391-425. PMID 174398 DOI: 10.1016/S0065-230X(08)60976-8  0.301
1975 Trosko JE, Yager JD. A sensitive method to measure physical and chemical carcinogen-induced "unscheduled DNA synthesis" in rapidly dividing eukaryotic cells. Experimental Cell Research. 88: 47-55. PMID 4472970 DOI: 10.1016/0014-4827(74)90616-8  0.333
1975 Trosko JE, Yager JD, Bowden GT, Butcher FR. The effects of several croton oil constituents on two types of DNA repair and cyclic nucleotide levels in mammalian cells in vitro. Chemico-Biological Interactions. 11: 191-205. PMID 168978 DOI: 10.1016/0009-2797(75)90099-X  0.397
1975 Chang C, Trosko J, Yotti L, Chu E. Mutagenicity of cancer-promoting agents in cultured Chinese hamster cells Mutation Research/Environmental Mutagenesis and Related Subjects. 31: 322. DOI: 10.1016/0165-1161(75)90124-7  0.34
1972 Trosko JE, Isoun M. Photosensitizing effect of trisoralen on DNA synthesis in human cells grown in vitro. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine. 19: 87-92. PMID 5316592 DOI: 10.1080/09553007114550101  0.368
1972 Trosko JE. Studies on deoxyribonucleic acid metabolism in human cells treated with lysergic acid diethylamide. Biochemical Pharmacology. 20: 3213-8. PMID 5132123 DOI: 10.1016/0006-2952(71)90127-4  0.311
1972 Cleaver JE, Thomas GH, Trosko JE, Lett JT. Excision repair (dimer excision, strand breakage and repair replication) in primary cultures of eukaryotic (bovine) cells. Experimental Cell Research. 74: 67-80. PMID 4627418 DOI: 10.1016/0014-4827(72)90482-X  0.3
1971 Trosko JE, Chu EH. Effects of caffeine on the induction of mutation in Chinese hamster cells by ultraviolet light. Mutation Research. 12: 337-40. PMID 5563947 DOI: 10.1016/0027-5107(71)90024-8  0.328
1971 Trosko JE, Isoun M. Lack of photoreactivation in human cells grown in vitro. International Journal of Radiation Biology and Related Studies in Physics, Chemistry, and Medicine. 18: 271-5. PMID 5312704 DOI: 10.1080/09553007014551091  0.408
1970 Trosko JE, Krause D, Isoun M. Sunlight-induced Pyrimidine Dimers in Human Cells in Vitro Nature. 228: 358-359. PMID 5473981 DOI: 10.1038/228358B0  0.375
1969 Trosko JE, Mansour VH. Photoreactivation of ultraviolet light-induced pyrimidine dimers in Ginkgo cells grown in vitro. Mutation Research. 7: 120-1. PMID 5801070 DOI: 10.1016/0027-5107(69)90056-6  0.356
1968 Trosko JE, Mansour VH. Response of Tobacco and Haplopappus Cells to Ultraviolet Irradiation after Posttreatment with Photoreactivating Light Radiation Research. 36: 333. DOI: 10.2307/3572656  0.387
1967 Trosko JE, Kasschau MR. STUDY OF PYRIMIDINE DIMERS IN MAMMALIAN CELLS SURVIVING LOW DOSES OF ULTRAVIOLET RADIATION Photochemistry and Photobiology. 6: 215-219. DOI: 10.1111/J.1751-1097.1967.Tb08806.X  0.334
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