| Year |
Citation |
Score |
| 2020 |
Sasaki N, Gomi F, Yoshimura H, Yamamoto M, Matsuda Y, Michishita M, Hatakeyama H, Kawano Y, Toyoda M, Korc M, Ishiwata T. FGFR4 Inhibitor BLU9931 Attenuates Pancreatic Cancer Cell Proliferation and Invasion While Inducing Senescence: Evidence for Senolytic Therapy Potential in Pancreatic Cancer. Cancers. 12. PMID 33066597 DOI: 10.3390/cancers12102976 |
0.443 |
|
| 2019 |
McElyea S, Korc M. Abstract C31: The glycosaminoglycan syndecan-4 facilitates pancreatic cancer progression and biologic aggressiveness Cancer Research. 79. DOI: 10.1158/1538-7445.Panca19-C31 |
0.369 |
|
| 2018 |
Lin CC, Korc M. Designer hydrogels: Shedding light on the physical chemistry of the pancreatic cancer microenvironment. Cancer Letters. PMID 30118843 DOI: 10.1016/j.canlet.2018.08.008 |
0.365 |
|
| 2018 |
Korc M. Beyond Kras: MYC Rules in Pancreatic Cancer. Cellular and Molecular Gastroenterology and Hepatology. 6: 223-224. PMID 30105283 DOI: 10.1016/j.jcmgh.2018.04.009 |
0.392 |
|
| 2018 |
Danilov AV, Neupane D, Nagaraja AS, Feofanova EV, Humphries LA, DiRenzo J, Korc M. Correction: DeltaNp63alpha-Mediated Induction of Epidermal Growth Factor Receptor Promotes Pancreatic Cancer Cell Growth and Chemoresistance. Plos One. 13: e0192927. PMID 29420628 DOI: 10.1371/journal.pone.0192927 |
0.396 |
|
| 2018 |
Prabhu L, Chen L, Safa A, Korc M, Zhang Z, Lu T. Abstract 4862: Protein arginine methyltransferase 5 as a tumor promoter and therapeutic target in gastrointestinal cancers Cancer Research. 78: 4862-4862. DOI: 10.1158/1538-7445.Am2018-4862 |
0.372 |
|
| 2017 |
Ouyang H, Gore J, Deitz S, Korc M. microRNA-10b enhances pancreatic cancer cell invasion by suppressing TIP30 expression and promoting EGF and TGF-β actions. Oncogene. PMID 28604742 DOI: 10.1038/onc.2017.190 |
0.361 |
|
| 2017 |
Prabhu L, Wei H, Chen L, Demir Ö, Sandusky G, Sun E, Wang J, Mo J, Zeng L, Fishel M, Safa A, Amaro R, Korc M, Zhang ZY, Lu T. Adapting AlphaLISA high throughput screen to discover a novel small-molecule inhibitor targeting protein arginine methyltransferase 5 in pancreatic and colorectal cancers. Oncotarget. PMID 28591716 DOI: 10.18632/Oncotarget.18102 |
0.324 |
|
| 2016 |
Liu HY, Greene T, Lin TY, Dawes CS, Korc M, Lin CC. Enzyme-mediated stiffening hydrogels for probing activation of pancreatic stellate cells. Acta Biomaterialia. PMID 27769941 DOI: 10.1016/j.actbio.2016.10.027 |
0.318 |
|
| 2016 |
Korc M. RelA: a tale of a stitch in time. The Journal of Clinical Investigation. PMID 27454293 DOI: 10.1172/JCI89156 |
0.326 |
|
| 2016 |
Gore AJ, Deitz SL, Palam LR, Craven KE, Korc M. Pancreatic cancer-associated retinoblastoma 1 dysfunction enables TGF-β to promote proliferation. The Journal of Clinical Investigation. 126: 2774. PMID 27367186 DOI: 10.1172/JCI88840 |
0.328 |
|
| 2016 |
Gore J, Imasuen-Williams IE, Conteh AM, Craven KE, Cheng M, Korc M. Combined targeting of TGF-beta, EGFR and HER2 suppresses lymphangiogenesis and metastasis in a pancreatic cancer model. Cancer Letters. PMID 27267807 DOI: 10.1016/j.canlet.2016.05.037 |
0.403 |
|
| 2016 |
Kleeff J, Korc M, Apte M, La Vecchia C, Johnson CD, Biankin AV, Neale RE, Tempero M, Tuveson DA, Hruban RH, Neoptolemos JP. Pancreatic cancer. Nature Reviews. Disease Primers. 2: 16022. PMID 27158978 DOI: 10.1038/nrdp.2016.22 |
0.348 |
|
| 2016 |
Muratore S, Zeng X, Korc M, McElyea S, Wilhelm J, Bellin M, Beilman G. Metastatic Pancreatic Adenocarcinoma After Total Pancreatectomy Islet Autotransplantation for Chronic Pancreatitis. American Journal of Transplantation : Official Journal of the American Society of Transplantation and the American Society of Transplant Surgeons. PMID 27137483 DOI: 10.1111/Ajt.13851 |
0.316 |
|
| 2015 |
Craven KE, Gore J, Wilson JL, Korc M. Angiogenic gene signature in human pancreatic cancer correlates with TGF-beta and inflammatory transcriptomes. Oncotarget. PMID 26586478 DOI: 10.18632/oncotarget.6345 |
0.404 |
|
| 2015 |
Palam LR, Gore J, Craven KE, Wilson JL, Korc M. Integrated stress response is critical for gemcitabine resistance in pancreatic ductal adenocarcinoma. Cell Death & Disease. 6: e1913. PMID 26469962 DOI: 10.1038/Cddis.2015.264 |
0.345 |
|
| 2015 |
Gore J, Craven KE, Wilson JL, Cote GA, Cheng M, Nguyen HV, Cramer HM, Sherman S, Korc M. TCGA data and patient-derived orthotopic xenografts highlight pancreatic cancer-associated angiogenesis. Oncotarget. 6: 7504-21. PMID 25762644 |
0.36 |
|
| 2015 |
Korc M. Pancreatic cancer-associated diabetes is an "exosomopathy". Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1508-10. PMID 25645860 DOI: 10.1158/1078-0432.CCR-14-2990 |
0.36 |
|
| 2015 |
Fishel ML, Cheng H, Korc M, Kelley MR. Abstract B19: Redox factor 1 (Ref-1) signaling in the interaction between pancreatic tumor cells and cancer-associated fibroblasts Cancer Research. 75. DOI: 10.1158/1538-7445.Panca2014-B19 |
0.324 |
|
| 2014 |
Ki CS, Lin TY, Korc M, Lin CC. Thiol-ene hydrogels as desmoplasia-mimetic matrices for modeling pancreatic cancer cell growth, invasion, and drug resistance. Biomaterials. 35: 9668-77. PMID 25176061 DOI: 10.1016/j.biomaterials.2014.08.014 |
0.396 |
|
| 2014 |
Gore J, Korc M. Pancreatic cancer stroma: friend or foe? Cancer Cell. 25: 711-2. PMID 24937454 DOI: 10.1016/j.ccr.2014.05.026 |
0.406 |
|
| 2014 |
Matsuda Y, Yoshimura H, Ueda J, Naito Z, Korc M, Ishiwata T. Nestin delineates pancreatic cancer stem cells in metastatic foci of NOD/Shi-scid IL2Rγ(null) (NOG) mice. The American Journal of Pathology. 184: 674-85. PMID 24412093 DOI: 10.1016/j.ajpath.2013.11.014 |
0.355 |
|
| 2014 |
Liu F, Gore AJ, Wilson JL, Korc M. DUSP1 is a novel target for enhancing pancreatic cancer cell sensitivity to gemcitabine. Plos One. 9: e84982. PMID 24409315 DOI: 10.1371/journal.pone.0084982 |
0.343 |
|
| 2014 |
Ueda J, Matsuda Y, Yamahatsu K, Uchida E, Naito Z, Korc M, Ishiwata T. Epithelial splicing regulatory protein 1 is a favorable prognostic factor in pancreatic cancer that attenuates pancreatic metastases. Oncogene. 33: 4485-95. PMID 24077287 DOI: 10.1038/onc.2013.392 |
0.462 |
|
| 2013 |
Norris AM, Gore A, Balboni A, Young A, Longnecker DS, Korc M. AGR2 is a SMAD4-suppressible gene that modulates MUC1 levels and promotes the initiation and progression of pancreatic intraepithelial neoplasia. Oncogene. 32: 3867-76. PMID 22945649 DOI: 10.1038/Onc.2012.394 |
0.447 |
|
| 2013 |
Wang Z, Ali S, Banerjee S, Bao B, Li Y, Azmi AS, Korc M, Sarkar FH. Activated K-Ras and INK4a/Arf deficiency promote aggressiveness of pancreatic cancer by induction of EMT consistent with cancer stem cell phenotype. Journal of Cellular Physiology. 228: 556-62. PMID 22806240 DOI: 10.1002/Jcp.24162 |
0.331 |
|
| 2012 |
Thornley JA, Trask HW, Ringelberg CS, Ridley CJ, Wang S, Sal-Lari RC, Moore JH, Korc M, Tomlinson CR. SMAD4-dependent polysome RNA recruitment in human pancreatic cancer cells. Molecular Carcinogenesis. 51: 771-82. PMID 22965423 DOI: 10.1002/Mc.20845 |
0.341 |
|
| 2012 |
Deharvengt S, Marmarelis M, Korc M. Concomitant targeting of EGF receptor, TGF-beta and SRC points to a novel therapeutic approach in pancreatic cancer. Plos One. 7: e39684. PMID 22761868 DOI: 10.1371/journal.pone.0039684 |
0.381 |
|
| 2012 |
Ishiwata T, Matsuda Y, Yamamoto T, Uchida E, Korc M, Naito Z. Enhanced expression of fibroblast growth factor receptor 2 IIIc promotes human pancreatic cancer cell proliferation. The American Journal of Pathology. 180: 1928-41. PMID 22440254 DOI: 10.1016/j.ajpath.2012.01.020 |
0.511 |
|
| 2012 |
Whipple CA, Young AL, Korc M. A KrasG12D-driven genetic mouse model of pancreatic cancer requires glypican-1 for efficient proliferation and angiogenesis Oncogene. 31: 2535-2544. PMID 21996748 DOI: 10.1038/Onc.2011.430 |
0.334 |
|
| 2012 |
Ebert M, Yokoyama M, Kobrin M, Friess H, Buchler M, Korc M. Increased mdm2 expression and immunoreactivity in human pancreatic ductal adenocarcinoma. International Journal of Oncology. 5: 1279-84. PMID 21559710 DOI: 10.3892/Ijo.5.6.1279 |
0.395 |
|
| 2012 |
Yokoyama M, Ebert M, Funatomi H, Friess H, Buchler M, Johnson G, Korc M. Amphiregulin is a potent mitogen in human pancreatic-cancer cells - correlation with patient survival. International Journal of Oncology. 6: 625-31. PMID 21556580 DOI: 10.3892/ijo.6.3.625 |
0.477 |
|
| 2012 |
Yokoyama M, Funatomi H, Kobrin M, Ebert M, Friess H, Buchler M, Korc M. Betacellulin, a member of the epidermal growth-factor family, is overexpressed in human pancreatic-cancer. International Journal of Oncology. 7: 825-9. PMID 21552910 DOI: 10.3892/ijo.7.4.825 |
0.526 |
|
| 2012 |
Yokoyama M, Funatomi H, Hope C, Damm D, Friess H, Buchler M, Abraham J, Korc M. Heparin-binding EGF-like growth factor expression and biological action in human pancreatic cancer cells. International Journal of Oncology. 8: 289-95. PMID 21544358 DOI: 10.3892/ijo.8.2.289 |
0.501 |
|
| 2012 |
Danilov AV, Srivastava A, Feofanova EV, Humphries LA, Direnzo J, Korc M. Abstract 3076: p53 homologue p63 trans-activates epidermal growth factor (EGF) receptor and 14-3-3α and thus promotes tumorigenesis and chemoresistance in pancreatic cancer Cancer Research. 72: 3076-3076. DOI: 10.1158/1538-7445.Am2012-3076 |
0.444 |
|
| 2011 |
Carrière C, Young AL, Gunn JR, Longnecker DS, Korc M. Acute pancreatitis accelerates initiation and progression to pancreatic cancer in mice expressing oncogenic Kras in the Nestin cell lineage Plos One. 6. PMID 22140463 DOI: 10.1371/Journal.Pone.0027725 |
0.346 |
|
| 2011 |
Preis M, Korc M. Signaling pathways in pancreatic cancer. Critical Reviews in Eukaryotic Gene Expression. 21: 115-29. PMID 22077151 |
0.458 |
|
| 2011 |
Danilov AV, Neupane D, Nagaraja AS, Feofanova EV, Humphries LA, DiRenzo J, Korc M. DeltaNp63alpha-mediated induction of epidermal growth factor receptor promotes pancreatic cancer cell growth and chemoresistance. Plos One. 6: e26815. PMID 22053213 DOI: 10.1371/Journal.Pone.0026815 |
0.519 |
|
| 2011 |
Carrire C, Gore AJ, Norris AM, Gunn JR, Young AL, Longnecker DS, Korc M. Deletion of Rb accelerates pancreatic carcinogenesis by oncogenic kras and impairs senescence in premalignant lesions Gastroenterology. 141: 1091-1101. PMID 21699781 DOI: 10.1053/J.Gastro.2011.05.041 |
0.41 |
|
| 2011 |
Sempere LF, Gunn JR, Korc M. A novel 3-dimensional culture system uncovers growth stimulatory actions by TGFβ in pancreatic cancer cells. Cancer Biology & Therapy. 12: 198-207. PMID 21613822 DOI: 10.4161/Cbt.12.3.15979 |
0.347 |
|
| 2011 |
Matsuda Y, Naito Z, Kawahara K, Nakazawa N, Korc M, Ishiwata T. Nestin is a novel target for suppressing pancreatic cancer cell migration, invasion and metastasis. Cancer Biology & Therapy. 11: 512-23. PMID 21258211 DOI: 10.4161/Cbt.11.5.14673 |
0.397 |
|
| 2011 |
Ueda J, Kawahara K, Fujii T, Yamahatsu K, Suzuki T, Matsuda Y, Uchida E, Korc M, Naito Z, Ishiwata T. Abstract 5240: Establishment of novel human pancreatic cancer cell lines from liver and lung metastases in NOD/SCID/γcnull(NOG) mice Cancer Research. 71: 5240-5240. DOI: 10.1158/1538-7445.Am2011-5240 |
0.374 |
|
| 2011 |
Whipple CA, Korc M. Abstract 2811: GPC1 promotes tumor growth and angiogenesis in a KrasG12D- Driven mouse model of pancreatic cancer Cancer Research. 71: 2811-2811. DOI: 10.1158/1538-7445.Am2011-2811 |
0.443 |
|
| 2011 |
Matsuda Y, Yamahatsu K, Kawahara K, Suzuki T, Fujii T, Yamamoto T, Korc M, Naito Z, Ishiwata T. Abstract 2457: Nestin regulates pancreatic cancer stem cell functions Cancer Research. 71: 2457-2457. DOI: 10.1158/1538-7445.Am2011-2457 |
0.401 |
|
| 2011 |
Wang Z, Banerjee S, Ahmad A, Azmi AS, Bao B, Ali S, Mohammad RM, Miele L, Korc M, Sarkar FH. Abstract 2385: Activated Kras and INK4a/Arf deficiency cooperate to produce pancreatic cancer involved with Notch and NF-κB pathways Cancer Research. 71: 2385-2385. DOI: 10.1158/1538-7445.Am2011-2385 |
0.31 |
|
| 2011 |
Danilov A, Neupane D, DiRenzo J, Korc M. Abstract 223: ΔNp63α, a p53 family member protein, promotes tumor progression in pancreatic cancer Cancer Research. 71: 223-223. DOI: 10.1158/1538-7445.Am2011-223 |
0.412 |
|
| 2011 |
Ishiwata T, Matsuda Y, Kawahara K, Yamamoto T, Teduka K, Suzuki T, Peng W, Korc M, Naito Z. Abstract 1204: Fibroblast growth factor receptor 2 as a novel therapeutic target for cancer cell growth and angiogenesis in human pancreatic cancer Cancer Research. 71: 1204-1204. DOI: 10.1158/1538-7445.Am2011-1204 |
0.513 |
|
| 2010 |
Preis M, Korc M. Kinase signaling pathways as targets for intervention in pancreatic cancer. Cancer Biology & Therapy. 9: 754-63. PMID 20234186 |
0.306 |
|
| 2010 |
Deharvengt SJ, Gunn JR, Pickett SB, Korc M. Intratumoral delivery of shRNA targeting cyclin D1 attenuates pancreatic cancer growth. Cancer Gene Therapy. 17: 325-33. PMID 19851352 DOI: 10.1038/Cgt.2009.75 |
0.385 |
|
| 2010 |
Ishiwata T, Matsuda Y, Kawahara K, Yamamoto T, Teduka K, Uchida E, Korc M, Naito Z. Abstract 4101: Fibroblast growth factor receptor (FGFR) 2 IIIc, is a novel molecular target for suppressing pancreatic cancer cell growth and migration Cancer Research. 70: 4101-4101. DOI: 10.1158/1538-7445.Am10-4101 |
0.514 |
|
| 2010 |
Matsuda Y, Ishiwata T, Kawamoto M, Yamomoto T, Kawahara K, Teduka K, Peng W, Yamahatsu K, Korc M, Naito Z. Abstract 408: Stem cell marker Nestin regulated the migration and invasion of pancreatic cancer cells Cancer Research. 70: 408-408. DOI: 10.1158/1538-7445.Am10-408 |
0.437 |
|
| 2009 |
Philip PA, Mooney M, Jaffe D, Eckhardt G, Moore M, Meropol N, Emens L, O'Reilly E, Korc M, Ellis L, Benedetti J, Rothenberg M, Willett C, Tempero M, Lowy A, et al. Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 5660-9. PMID 19858397 DOI: 10.1200/Jco.2009.21.9022 |
0.326 |
|
| 2009 |
Korc M. Smad4: gatekeeper gene in head and neck squamous cell carcinoma. The Journal of Clinical Investigation. 119: 3208-11. PMID 19841540 DOI: 10.1172/Jci41230 |
0.312 |
|
| 2009 |
Shin S, Asano T, Yao Y, Zhang R, Claret FX, Korc M, Sabapathy K, Menter DG, Abbruzzese JL, Reddy SA. Activator protein-1 has an essential role in pancreatic cancer cells and is regulated by a novel Akt-mediated mechanism. Molecular Cancer Research : McR. 7: 745-54. PMID 19435822 DOI: 10.1158/1541-7786.Mcr-08-0462 |
0.365 |
|
| 2009 |
Carrière C, Young AL, Gunn JR, Longnecker DS, Korc M. Acute pancreatitis markedly accelerates pancreatic cancer progression in mice expressing oncogenic Kras. Biochemical and Biophysical Research Communications. 382: 561-5. PMID 19292977 DOI: 10.1016/J.Bbrc.2009.03.068 |
0.405 |
|
| 2009 |
Seeley ES, Carrière C, Goetze T, Longnecker DS, Korc M. Pancreatic cancer and precursor pancreatic intraepithelial neoplasia lesions are devoid of primary cilia. Cancer Research. 69: 422-30. PMID 19147554 DOI: 10.1158/0008-5472.CAN-08-1290 |
0.447 |
|
| 2009 |
Ketterer K, Kong B, Frank D, Giese NA, Bauer A, Hoheisel J, Korc M, Kleeff J, Michalski CW, Friess H. Neuromedin U is overexpressed in pancreatic cancer and increases invasiveness via the hepatocyte growth factor c-Met pathway. Cancer Letters. 277: 72-81. PMID 19118941 DOI: 10.1016/J.Canlet.2008.11.028 |
0.481 |
|
| 2009 |
Kawamoto M, Ishiwata T, Cho K, Uchida E, Korc M, Naito Z, Tajiri T. Nestin expression correlates with nerve and retroperitoneal tissue invasion in pancreatic cancer. Human Pathology. 40: 189-98. PMID 18799194 DOI: 10.1016/J.Humpath.2008.02.022 |
0.44 |
|
| 2009 |
Formentini A, Prokopchuk O, Sträter J, Kleeff J, Grochola LF, Leder G, Henne-Bruns D, Korc M, Kornmann M. Interleukin-13 exerts autocrine growth-promoting effects on human pancreatic cancer, and its expression correlates with a propensity for lymph node metastases. International Journal of Colorectal Disease. 24: 57-67. PMID 18758789 DOI: 10.1007/S00384-008-0550-9 |
0.311 |
|
| 2008 |
Whipple CA, Lander AD, Korc M. Discovery of a novel molecule that regulates tumor growth and metastasis. Thescientificworldjournal. 8: 1250-3. PMID 19082421 DOI: 10.1100/Tsw.2008.152 |
0.403 |
|
| 2008 |
Neupane D, Korc M. 14-3-3sigma Modulates pancreatic cancer cell survival and invasiveness. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 7614-23. PMID 19047086 DOI: 10.1158/1078-0432.CCR-08-1366 |
0.422 |
|
| 2008 |
Sempere LF, Korc M. Shining the spotlight on shed KRAS in pancreatic cancer. Cancer Biology & Therapy. 7: 361-3. PMID 18614859 DOI: 10.4161/Cbt.7.3.5582 |
0.456 |
|
| 2008 |
Whipple C, Korc M. Targeting angiogenesis in pancreatic cancer: Rationale and pitfalls Langenbeck's Archives of Surgery. 393: 901-910. PMID 18210149 DOI: 10.1007/S00423-008-0280-Z |
0.374 |
|
| 2008 |
Aikawa T, Whipple CA, Lopez ME, Gunn J, Young A, Lander AD, Korc M. Glypican-1 modulates the angiogenic and metastatic potential of human and mouse cancer cells. The Journal of Clinical Investigation. 118: 89-99. PMID 18064304 DOI: 10.1172/Jci32412 |
0.451 |
|
| 2008 |
Ishiwata T, Kawamoto M, Kawamoto Y, Teduka K, Matsuda Y, Onda M, Uchida E, Tajiri T, Korc M, Naito Z. OVER-EXPRESSION OF FGFR2 IIIC ISOFORM ENHANCES THE GROWTH OF PANCREATIC CANCER Pancreas. 37: 476. DOI: 10.1097/01.mpa.0000335480.46603.d9 |
0.459 |
|
| 2007 |
Matsushita A, Götze T, Korc M. Hepatocyte growth factor-mediated cell invasion in pancreatic cancer cells is dependent on neuropilin-1. Cancer Research. 67: 10309-16. PMID 17974973 DOI: 10.1158/0008-5472.CAN-07-3256 |
0.316 |
|
| 2007 |
Korc M. Pancreatic cancer-associated stroma production. American Journal of Surgery. 194: S84-6. PMID 17903452 DOI: 10.1016/J.Amjsurg.2007.05.004 |
0.457 |
|
| 2007 |
Fukasawa M, Matsushita A, Korc M. Neuropilin-1 interacts with integrin beta1 and modulates pancreatic cancer cell growth, survival and invasion. Cancer Biology & Therapy. 6: 1173-80. PMID 17726369 |
0.331 |
|
| 2007 |
Liu Z, Ishiwata T, Zhou S, Maier S, Henne-Bruns D, Korc M, Bachem M, Kornmann M. Human fibroblast growth factor receptor 1-IIIb is a functional fibroblast growth factor receptor expressed in the pancreas and involved in proliferation and movement of pancreatic ductal cells. Pancreas. 35: 147-57. PMID 17632321 DOI: 10.1097/mpa.0b013e318053e7e3 |
0.334 |
|
| 2007 |
Cho K, Ishiwata T, Uchida E, Nakazawa N, Korc M, Naito Z, Tajiri T. Enhanced expression of keratinocyte growth factor and its receptor correlates with venous invasion in pancreatic cancer. The American Journal of Pathology. 170: 1964-74. PMID 17525264 DOI: 10.2353/Ajpath.2007.060935 |
0.467 |
|
| 2007 |
Liu Z, Neiss N, Zhou S, Henne-Bruns D, Korc M, Bachem M, Kornmann M. Identification of a fibroblast growth factor receptor 1 splice variant that inhibits pancreatic cancer cell growth. Cancer Research. 67: 2712-9. PMID 17363592 DOI: 10.1158/0008-5472.CAN-06-3843 |
0.492 |
|
| 2007 |
Carrière C, Seeley ES, Goetze T, Longnecker DS, Korc M. The Nestin progenitor lineage is the compartment of origin for pancreatic intraepithelial neoplasia. Proceedings of the National Academy of Sciences of the United States of America. 104: 4437-42. PMID 17360542 DOI: 10.1073/pnas.0701117104 |
0.311 |
|
| 2007 |
Arnold NB, Arkus N, Gunn J, Korc M. The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces growth inhibition and enhances gemcitabine-induced cell death in pancreatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 18-26. PMID 17200334 DOI: 10.1158/1078-0432.Ccr-06-0914 |
0.419 |
|
| 2007 |
Wildi S, Kleeff J, Mayerle J, Zimmermann A, Böttinger EP, Wakefield L, Büchler MW, Friess H, Korc M. Suppression of transforming growth factor beta signalling aborts caerulein induced pancreatitis and eliminates restricted stimulation at high caerulein concentrations. Gut. 56: 685-92. PMID 17135311 DOI: 10.1136/Gut.2006.105833 |
0.31 |
|
| 2007 |
Kolb A, Kleeff J, Arnold N, Giese NA, Giese T, Korc M, Friess H. Expression and differential signaling of heregulins in pancreatic cancer cells. International Journal of Cancer. 120: 514-23. PMID 17096356 DOI: 10.1002/Ijc.22360 |
0.558 |
|
| 2007 |
Matsushita A, Götze T, Kawamoto M, Cho K, Nakamura Y, Aimoto T, Uchida E, Ishiwata T, Naito Z, Tajiri T, Korc M. NEUROPILIN-1 ASSOCIATION WITH c-MET IN PANCREATIC CANCER CELLS ENHANCES HEPATOCYTE GROWTH FACTOR-MEDIATED CELL INVASION Pancreas. 35: 415. DOI: 10.1097/01.mpa.0000297744.81562.ac |
0.454 |
|
| 2007 |
Formentini A, Prokopchuk O, Leder G, Straeter J, Kleeff J, Korc M, Henne-Bruns D, Kornmann M. 3513 POSTER Interleukin-13 exerts autocrine growth promoting effects in human pancreatic cancer and its expression correlates with a propensity for lymph node metastases European Journal of Cancer Supplements. 5: 263. DOI: 10.1016/s1359-6349(07)71016-9 |
0.325 |
|
| 2006 |
Kayed H, Kleeff J, Keleg S, Jiang X, Penzel R, Giese T, Zentgraf H, Büchler MW, Korc M, Friess H. Correlation of glypican-1 expression with TGF-beta, BMP, and activin receptors in pancreatic ductal adenocarcinoma. International Journal of Oncology. 29: 1139-48. PMID 17016645 |
0.428 |
|
| 2006 |
Aikawa T, Gunn J, Spong SM, Klaus SJ, Korc M. Connective tissue growth factor-specific antibody attenuates tumor growth, metastasis, and angiogenesis in an orthotopic mouse model of pancreatic cancer. Molecular Cancer Therapeutics. 5: 1108-16. PMID 16731742 DOI: 10.1158/1535-7163.MCT-05-0516 |
0.469 |
|
| 2006 |
Ishiwata T, Kudo M, Onda M, Fujii T, Teduka K, Suzuki T, Korc M, Naito Z. Defined localization of nestin-expressing cells in L-arginine-induced acute pancreatitis. Pancreas. 32: 360-8. PMID 16670618 DOI: 10.1097/01.mpa.0000220860.01120.21 |
0.308 |
|
| 2006 |
Guo J, Kleeff J, Zhao Y, Li J, Giese T, Esposito I, Büchler MW, Korc M, Friess H. Yes-associated protein (YAP65) in relation to Smad7 expression in human pancreatic ductal adenocarcinoma. International Journal of Molecular Medicine. 17: 761-7. PMID 16596258 DOI: 10.3892/Ijmm.17.5.761 |
0.459 |
|
| 2006 |
Kayed H, Kleeff J, Kolb A, Ketterer K, Keleg S, Felix K, Giese T, Penzel R, Zentgraf H, Büchler MW, Korc M, Friess H. FXYD3 is overexpressed in pancreatic ductal adenocarcinoma and influences pancreatic cancer cell growth. International Journal of Cancer. 118: 43-54. PMID 16003754 DOI: 10.1002/Ijc.21257 |
0.49 |
|
| 2006 |
Neupane D, Korc M. OVEREXPRESSION OF 14-3-3?? CONFERS A GROWTH AND SURVIVAL ADVANTAGE IN PANCREATIC CANCER Pancreas. 33: 486. DOI: 10.1097/00006676-200611000-00168 |
0.424 |
|
| 2006 |
Kornmann M, Zhou S, Henne-Bruns D, Korc M, Bachem M, Liu Z. EXPRESSION OF FGFR1-IIIB INHIBITS PANCREATIC CANCER CELL GROWTH IN VITRO AND IN VIVO Pancreas. 33: 475. DOI: 10.1097/00006676-200611000-00130 |
0.486 |
|
| 2005 |
Yasutome M, Gunn J, Korc M. Restoration of Smad4 in BxPC3 pancreatic cancer cells attenuates proliferation without altering angiogenesis. Clinical & Experimental Metastasis. 22: 461-73. PMID 16320109 DOI: 10.1007/S10585-005-2891-X |
0.38 |
|
| 2005 |
Ding K, Lopez-Burks M, Sánchez-Duran JA, Korc M, Lander AD. Growth factor-induced shedding of syndecan-1 confers glypican-1 dependence on mitogenic responses of cancer cells. The Journal of Cell Biology. 171: 729-38. PMID 16286510 DOI: 10.1083/Jcb.200508010 |
0.365 |
|
| 2005 |
Chan JK, Pham H, You XJ, Cloven NG, Burger RA, Rose GS, Van Nostrand K, Korc M, Disaia PJ, Fan H. Suppression of ovarian cancer cell tumorigenicity and evasion of Cisplatin resistance using a truncated epidermal growth factor receptor in a rat model. Cancer Research. 65: 3243-8. PMID 15833856 DOI: 10.1158/0008-5472.Can-03-3013 |
0.37 |
|
| 2005 |
Boyer Arnold N, Korc M. Smad7 abrogates transforming growth factor-beta1-mediated growth inhibition in COLO-357 cells through functional inactivation of the retinoblastoma protein. The Journal of Biological Chemistry. 280: 21858-66. PMID 15811853 DOI: 10.1074/Jbc.M500583200 |
0.312 |
|
| 2004 |
Li J, Kleeff J, Kayed H, Felix K, Penzel R, Büchler MW, Korc M, Friess H. Glypican-1 antisense transfection modulates TGF-beta-dependent signaling in Colo-357 pancreatic cancer cells. Biochemical and Biophysical Research Communications. 320: 1148-55. PMID 15249209 DOI: 10.1016/J.Bbrc.2004.06.063 |
0.471 |
|
| 2004 |
Li J, Kleeff J, Giese N, Büchler MW, Korc M, Friess H. Gefitinib ('Iressa', ZD1839), a selective epidermal growth factor receptor tyrosine kinase inhibitor, inhibits pancreatic cancer cell growth, invasion, and colony formation. International Journal of Oncology. 25: 203-10. PMID 15202007 |
0.477 |
|
| 2004 |
Fukasawa M, Korc M. Vascular endothelial growth factor-trap suppresses tumorigenicity of multiple pancreatic cancer cell lines. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 3327-32. PMID 15161686 DOI: 10.1158/1078-0432.Ccr-03-0820 |
0.345 |
|
| 2004 |
Arnold NB, Ketterer K, Kleeff J, Friess H, Büchler MW, Korc M. Thioredoxin is downstream of Smad7 in a pathway that promotes growth and suppresses cisplatin-induced apoptosis in pancreatic cancer. Cancer Research. 64: 3599-606. PMID 15150118 DOI: 10.1158/0008-5472.Can-03-2999 |
0.457 |
|
| 2004 |
Guweidhi A, Kleeff J, Giese N, El Fitori J, Ketterer K, Giese T, Büchler MW, Korc M, Friess H. Enhanced expression of 14-3-3sigma in pancreatic cancer and its role in cell cycle regulation and apoptosis. Carcinogenesis. 25: 1575-85. PMID 15073049 DOI: 10.1093/carcin/bgh159 |
0.457 |
|
| 2004 |
Fukahi K, Fukasawa M, Neufeld G, Itakura J, Korc M. Aberrant expression of neuropilin-1 and -2 in human pancreatic cancer cells. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 581-90. PMID 14760080 |
0.368 |
|
| 2004 |
Guo J, Kleeff J, Li J, Ding J, Hammer J, Zhao Y, Giese T, Korc M, Büchler MW, Friess H. Expression and functional significance of CDC25B in human pancreatic ductal adenocarcinoma. Oncogene. 23: 71-81. PMID 14712212 DOI: 10.1038/Sj.Onc.1206926 |
0.469 |
|
| 2004 |
Kleeff J, Kothari NH, Friess H, Fan H, Korc M. Adenovirus-mediated transfer of a truncated fibroblast growth factor (FGF) type I receptor blocks FGF-2 signaling in multiple pancreatic cancer cell lines. Pancreas. 28: 25-30. PMID 14707726 DOI: 10.1097/00006676-200401000-00004 |
0.448 |
|
| 2003 |
Friess H, Ding J, Kleeff J, Fenkell L, Rosinski JA, Guweidhi A, Reidhaar-Olson JF, Korc M, Hammer J, Büchler MW. Microarray-based identification of differentially expressed growth- and metastasis-associated genes in pancreatic cancer Cellular and Molecular Life Sciences. 60: 1180-1199. PMID 12861384 DOI: 10.1007/S00018-003-3036-5 |
0.333 |
|
| 2003 |
Liao Q, Guo J, Kleeff J, Zimmermann A, Büchler MW, Korc M, Friess H. Down-regulation of the dual-specificity phosphatase MKP-1 suppresses tumorigenicity of pancreatic cancer cells. Gastroenterology. 124: 1830-45. PMID 12806617 DOI: 10.1016/S0016-5085(03)00398-6 |
0.39 |
|
| 2003 |
Friess H, Zhu Z, Liard V, Shi X, Shrikhande SV, Wang L, Lieb K, Korc M, Palma C, Zimmermann A, Reubi JC, Büchler MW. Neurokinin-1 receptor expression and its potential effects on tumor growth in human pancreatic cancer. Laboratory Investigation; a Journal of Technical Methods and Pathology. 83: 731-42. PMID 12746482 DOI: 10.1097/01.Lab.0000067499.57309.F6 |
0.425 |
|
| 2003 |
Korc M. Pathways for aberrant angiogenesis in pancreatic cancer. Molecular Cancer. 2: 8. PMID 12556241 DOI: 10.1186/1476-4598-2-8 |
0.47 |
|
| 2003 |
Kleeff J, Friess H, Buechler M, Kothari N, Datta S, Fan H, Korc M. Adenovirus mediated transfer of a truncated fibroblast growth factor (FGF) typ I receptor blocks FGF2 signaling in pancreatic cancer cells Gastroenterology. 124: A104. DOI: 10.1016/S0016-5085(03)80511-5 |
0.443 |
|
| 2002 |
Zhu Z, Kleeff J, Kayed H, Wang L, Korc M, Büchler MW, Friess H. Nerve growth factor and enhancement of proliferation, invasion, and tumorigenicity of pancreatic cancer cells. Molecular Carcinogenesis. 35: 138-47. PMID 12410565 DOI: 10.1002/Mc.10083 |
0.508 |
|
| 2002 |
Schneider D, Kleeff J, Berberat PO, Zhu Z, Korc M, Friess H, Büchler MW. Induction and expression of betaig-h3 in pancreatic cancer cells. Biochimica Et Biophysica Acta. 1588: 1-6. PMID 12379307 DOI: 10.1016/S0925-4439(02)00052-2 |
0.399 |
|
| 2002 |
Zhu Z, Friess H, Kleeff J, Wang L, Wirtz M, Zimmermann A, Korc M, Büchler MW. Glypican-3 expression is markedly decreased in human gastric cancer but not in esophageal cancer. American Journal of Surgery. 184: 78-83. PMID 12135726 DOI: 10.1016/S0002-9610(02)00884-X |
0.327 |
|
| 2002 |
Kornmann M, Ishiwata T, Matsuda K, Lopez ME, Fukahi K, Asano G, Beger HG, Korc M. IIIc isoform of fibroblast growth factor receptor 1 is overexpressed in human pancreatic cancer and enhances tumorigenicity of hamster ductal cells. Gastroenterology. 123: 301-13. PMID 12105858 DOI: 10.1053/Gast.2002.34174 |
0.443 |
|
| 2002 |
Kleeff J, Fukahi K, Lopez ME, Friess H, Büchler MW, Sosnowski BA, Korc M. Targeting of suicide gene delivery in pancreatic cancer cells via FGF receptors. Cancer Gene Therapy. 9: 522-32. PMID 12032663 DOI: 10.1038/Sj.Cgt.7700464 |
0.46 |
|
| 2002 |
Kornmann M, Lopez ME, Beger HG, Korc M. Expression of the IIIc variant of FGF receptor-1 confers mitogenic responsiveness to heparin and FGF-5 in TAKA-1 pancreatic ductal cells. International Journal of Pancreatology : Official Journal of the International Association of Pancreatology. 29: 85-92. PMID 11876253 DOI: 10.1385/Ijgc:29:2:085 |
0.356 |
|
| 2002 |
di Mola FF, Friess H, Riesle E, Koliopanos A, Büchler P, Zhu Z, Brigstock DR, Korc M, Büchler MW. Connective tissue growth factor is involved in pancreatic repair and tissue remodeling in human and rat acute necrotizing pancreatitis. Annals of Surgery. 235: 60-7. PMID 11753043 DOI: 10.1097/00000658-200201000-00008 |
0.321 |
|
| 2002 |
Kleeff J, Shi X, Bode HP, Hoover K, Shrikhande S, Bryant PJ, Korc M, Büchler MW, Friess H. Altered expression and localization of the tight junction protein ZO-1 in primary and metastatic pancreatic cancer. Pancreas. 23: 259-65. PMID 11590321 DOI: 10.1097/00006676-200110000-00006 |
0.333 |
|
| 2001 |
Xu Z, Friess H, Solioz M, Aebi S, Korc M, Kleeff J, Büchler MW. Bcl-x(L) antisense oligonucleotides induce apoptosis and increase sensitivity of pancreatic cancer cells to gemcitabine. International Journal of Cancer. 94: 268-74. PMID 11668508 DOI: 10.1002/Ijc.1447 |
0.348 |
|
| 2001 |
Wildi S, Kleeff J, Maruyama H, Maurer CA, Büchler MW, Korc M. Overexpression of activin A in stage IV colorectal cancer. Gut. 49: 409-17. PMID 11511564 DOI: 10.1136/Gut.49.3.409 |
0.406 |
|
| 2001 |
Friess H, Guo XZ, Tempia-Caliera AA, Fukuda A, Martignoni ME, Zimmermann A, Korc M, Büchler MW. Differential expression of metastasis-associated genes in papilla of vater and pancreatic cancer correlates with disease stage. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 19: 2422-32. PMID 11331321 DOI: 10.1200/Jco.2001.19.9.2422 |
0.396 |
|
| 2001 |
Tang RF, Itakura J, Aikawa T, Matsuda K, Fujii H, Korc M, Matsumoto Y. Overexpression of lymphangiogenic growth factor VEGF-C in human pancreatic cancer. Pancreas. 22: 285-92. PMID 11291931 DOI: 10.1097/00006676-200104000-00010 |
0.388 |
|
| 2001 |
Luo J, Guo P, Matsuda K, Truong N, Lee A, Chun C, Cheng SY, Korc M. Pancreatic cancer cell-derived vascular endothelial growth factor is biologically active in vitro and enhances tumorigenicity in vivo. International Journal of Cancer. 92: 361-9. PMID 11291072 DOI: 10.1002/Ijc.1202 |
0.387 |
|
| 2001 |
Lu Z, Kleeff J, Shrikhande S, Zimmermann T, Korc M, Friess H, Büchler MW. Expression of the multidrug-resistance 1 (MDR1) gene and prognosis in human pancreatic cancer. Pancreas. 21: 240-7. PMID 11039467 DOI: 10.1097/00006676-200010000-00004 |
0.316 |
|
| 2001 |
Itakura J, Tang R, Aikawa T, Fujii H, Korc M, Matsumoto Y. Overexpression of lymphangiogenic growth factor VEGF-C in human pancreatic cancer European Journal of Cancer. 37: S40. DOI: 10.1016/S0959-8049(01)80627-4 |
0.379 |
|
| 2000 |
Conejo JR, Kleeff J, Koliopanos A, Matsuda K, Zhu ZW, Goecke H, Bicheng N, Zimmermann A, Korc M, Friess H, Büchler MW. Syndecan-1 expression is up-regulated in pancreatic but not in other gastrointestinal cancers. International Journal of Cancer. 88: 12-20. PMID 10962434 DOI: 10.1002/1097-0215(20001001)88:1<12::Aid-Ijc3>3.0.Co;2-T |
0.485 |
|
| 2000 |
Zhu Z, Kleeff J, Friess H, Wang L, Zimmermann A, Yarden Y, Büchler MW, Korc M. Epiregulin is Up-regulated in pancreatic cancer and stimulates pancreatic cancer cell growth. Biochemical and Biophysical Research Communications. 273: 1019-24. PMID 10891365 DOI: 10.1006/Bbrc.2000.3033 |
0.512 |
|
| 2000 |
Kleeff J, Kornmann M, Sawhney H, Korc M. Actinomycin D induces apoptosis and inhibits growth of pancreatic cancer cells. International Journal of Cancer. 86: 399-407. PMID 10760829 DOI: 10.1002/(Sici)1097-0215(20000501)86:3<399::Aid-Ijc15>3.0.Co;2-G |
0.439 |
|
| 2000 |
Kornmann M, Ishiwata T, Kleeff J, Beger HG, Korc M. Fas and Fas-ligand expression in human pancreatic cancer. Annals of Surgery. 231: 368-79. PMID 10714630 DOI: 10.1097/00000658-200003000-00010 |
0.397 |
|
| 2000 |
Kornmann M, Ishiwata T, Maruyama H, Beger HG, Korc M. Coexpression of FAS and FAS-ligand in chronic pancreatitis: correlation with apoptosis. Pancreas. 20: 123-8. PMID 10707926 DOI: 10.1097/00006676-200003000-00003 |
0.313 |
|
| 2000 |
Friess H, Wang L, Zhu Z, Gerber R, Schröder M, Fukuda A, Zimmermann A, Korc M, Büchler MW. Growth factor receptors are differentially expressed in cancers of the papilla of vater and pancreas. Annals of Surgery. 230: 767-74; discussion 7. PMID 10615931 DOI: 10.1097/00000658-199912000-00005 |
0.456 |
|
| 2000 |
Itakura J, Ishiwata T, Shen B, Kornmann M, Korc M. Concomitant over-expression of vascular endothelial growth factor and its receptors in pancreatic cancer. International Journal of Cancer. 85: 27-34. PMID 10585578 DOI: 10.1002/(Sici)1097-0215(20000101)85:1<27::Aid-Ijc5>3.0.Co;2-8 |
0.45 |
|
| 2000 |
Wagner M, Kleeff J, Friess H, Büchler MW, Korc M. Enhanced expression of the type II transforming growth factor-beta receptor is associated with decreased survival in human pancreatic cancer. Pancreas. 19: 370-6. PMID 10547197 DOI: 10.1097/00006676-199911000-00008 |
0.467 |
|
| 2000 |
Friess H, Kleeff J, Korc M, Büchler MW. Molecular aspects of pancreatic cancer and future perspectives. Digestive Surgery. 16: 281-90. PMID 10449972 DOI: 10.1159/000018737 |
0.469 |
|
| 2000 |
Kornmann M, Ishiwata T, Lopez ME, Beger HG, Korc M. The IIIc splice variant of FGF receptor-1 contributesto the transformation of pancreatic ductal cells in vitro and in vivo Gastroenterology. 118: A1056. DOI: 10.1016/S0016-5085(00)86375-1 |
0.333 |
|
| 2000 |
Wildi S, Kleeff JH, Maruyama H, Friess H, Maurer C, Buchler MW, Korc M. Reduction of the angiostatic chemokine SF-1 and concomitant increase of its receptor CXCR-4 in colorectal cancer Gastroenterology. 118: A769. DOI: 10.1016/S0016-5085(00)85215-4 |
0.325 |
|
| 2000 |
Xu Z, Friess H, Aebi S, Korc M, Kleeff JH, Buchler MW. Increased sensitivity to gemcitabine following Bcl-xL antisense treatment in pancreatic cancer cells Gastroenterology. 118: A521. DOI: 10.1016/S0016-5085(00)84211-0 |
0.405 |
|
| 2000 |
Lopez ME, Korc M. Novel type I fibroblast growth factor receptor in pancreatic cancer Gastroenterology. 118: A183. DOI: 10.1016/S0016-5085(00)82806-1 |
0.437 |
|
| 1999 |
Zhu Z, Friess H, diMola FF, Zimmermann A, Graber HU, Korc M, Büchler MW. Nerve growth factor expression correlates with perineural invasion and pain in human pancreatic cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 17: 2419-28. PMID 10561305 DOI: 10.1200/Jco.1999.17.8.2419 |
0.404 |
|
| 1999 |
Friess H, Fukuda A, Tang WH, Eichenberger A, Furlan N, Zimmermann A, Korc M, Büchler MW. Concomitant analysis of the epidermal growth factor receptor family in esophageal cancer: overexpression of epidermal growth factor receptor mRNA but not of c-erbB-2 and c-erbB-3. World Journal of Surgery. 23: 1010-8. PMID 10512940 DOI: 10.1007/S002689900616 |
0.363 |
|
| 1999 |
Kleeff J, Wildi S, Kumbasar A, Friess H, Lander AD, Korc M. Stable transfection of a glypican-1 antisense construct decreases tumorigenicity in PANC-1 pancreatic carcinoma cells. Pancreas. 19: 281-8. PMID 10505759 DOI: 10.1097/00006676-199910000-00009 |
0.483 |
|
| 1999 |
Kleeff J, Friess H, Simon P, Susmallian S, Büchler P, Zimmermann A, Büchler MW, Korc M. Overexpression of Smad2 and colocalization with TGF-beta1 in human pancreatic cancer. Digestive Diseases and Sciences. 44: 1793-802. PMID 10505717 DOI: 10.1023/A:1018882320500 |
0.406 |
|
| 1999 |
Kleeff J, Ishiwata T, Maruyama H, Friess H, Truong P, Büchler MW, Falb D, Korc M. The TGF-beta signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer. Oncogene. 18: 5363-72. PMID 10498890 DOI: 10.1038/Sj.Onc.1202909 |
0.381 |
|
| 1999 |
Maruyama H, Kleeff J, Wildi S, Friess H, Büchler MW, Israel MA, Korc M. Id-1 and Id-2 are overexpressed in pancreatic cancer and in dysplastic lesions in chronic pancreatitis. The American Journal of Pathology. 155: 815-22. PMID 10487839 DOI: 10.1016/S0002-9440(10)65180-2 |
0.472 |
|
| 1999 |
Graber HU, Friess H, Zimmermann A, Korc M, Adler G, Schmid R, Büchler MW. Bak expression and cell death occur in peritumorous tissue but not in pancreatic cancer cells. Journal of Gastrointestinal Surgery : Official Journal of the Society For Surgery of the Alimentary Tract. 3: 74-80; discussion 81. PMID 10457328 DOI: 10.1016/S1091-255X(99)80012-2 |
0.408 |
|
| 1999 |
Kleeff J, Kusama T, Rossi DL, Ishiwata T, Maruyama H, Friess H, Büchler MW, Zlotnik A, Korc M. Detection and localization of Mip-3alpha/LARC/Exodus, a macrophage proinflammatory chemokine, and its CCR6 receptor in human pancreatic cancer. International Journal of Cancer. 81: 650-7. PMID 10225458 DOI: 10.1002/(Sici)1097-0215(19990517)81:4<650::Aid-Ijc23>3.0.Co;2-# |
0.379 |
|
| 1999 |
Kleeff J, Maruyama H, Ishiwata T, Sawhney H, Friess H, Büchler MW, Korc M. Bone morphogenetic protein 2 exerts diverse effects on cell growth in vitro and is expressed in human pancreatic cancer in vivo. Gastroenterology. 116: 1202-16. PMID 10220513 DOI: 10.1016/S0016-5085(99)70024-7 |
0.447 |
|
| 1999 |
Ebert M, Yokoyama M, Ishiwata T, Friess H, Büchler MW, Malfertheiner P, Korc M. Alteration of fibroblast growth factor and receptor expression after acute pancreatitis in humans. Pancreas. 18: 240-6. PMID 10206481 DOI: 10.1097/00006676-199904000-00004 |
0.379 |
|
| 1999 |
Kleeff J, Maruyama H, Friess H, Büchler MW, Falb D, Korc M. Smad6 suppresses TGF-beta-induced growth inhibition in COLO-357 pancreatic cancer cells and is overexpressed in pancreatic cancer. Biochemical and Biophysical Research Communications. 255: 268-73. PMID 10049697 DOI: 10.1006/Bbrc.1999.0171 |
0.421 |
|
| 1999 |
Graber HU, Friess H, Kaufmann B, Willi D, Zimmermann A, Korc M, Büchler MW. ErbB-4 mRNA expression is decreased in non-metastatic pancreatic cancer. International Journal of Cancer. Journal International Du Cancer. 84: 24-7. PMID 9988227 DOI: 10.1002/(Sici)1097-0215(19990219)84:1<24::Aid-Ijc5>3.0.Co;2-2 |
0.505 |
|
| 1998 |
Friess H, Lu Z, Graber HU, Zimmermann A, Adler G, Korc M, Schmid RM, Büchler MW. bax, but not bcl-2, influences the prognosis of human pancreatic cancer. Gut. 43: 414-21. PMID 9863489 DOI: 10.1136/Gut.43.3.414 |
0.415 |
|
| 1998 |
Kleeff J, Ishiwata T, Kumbasar A, Friess H, Büchler MW, Lander AD, Korc M. The cell-surface heparan sulfate proteoglycan glypican-1 regulates growth factor action in pancreatic carcinoma cells and is overexpressed in human pancreatic cancer. The Journal of Clinical Investigation. 102: 1662-73. PMID 9802880 DOI: 10.1172/Jci4105 |
0.504 |
|
| 1998 |
Wagner M, Kleeff J, Lopez ME, Bockman I, Massaqué J, Korc M. Transfection of the type I TGF-beta receptor restores TGF-beta responsiveness in pancreatic cancer. International Journal of Cancer. 78: 255-60. PMID 9754660 DOI: 10.1002/(Sici)1097-0215(19981005)78:2<255::Aid-Ijc21>3.0.Co;2-8 |
0.317 |
|
| 1998 |
Kleeff J, Ishiwata T, Friess H, Büchler MW, Korc M. Concomitant over-expression of activin/inhibin beta subunits and their receptors in human pancreatic cancer. International Journal of Cancer. 77: 860-8. PMID 9714055 DOI: 10.1002/(Sici)1097-0215(19980911)77:6<860::Aid-Ijc11>3.0.Co;2-5 |
0.532 |
|
| 1998 |
Maurer CA, Friess H, Kretschmann B, Zimmermann A, Stauffer A, Baer HU, Korc M, Büchler MW. Increased expression of erbB3 in colorectal cancer is associated with concomitant increase in the level of erbB2. Human Pathology. 29: 771-7. PMID 9712416 DOI: 10.1016/S0046-8177(98)90444-0 |
0.429 |
|
| 1998 |
Kornmann M, Beger HG, Korc M. Role of fibroblast growth factors and their receptors in pancreatic cancer and chronic pancreatitis. Pancreas. 17: 169-75. PMID 9700949 DOI: 10.1097/00006676-199808000-00010 |
0.46 |
|
| 1998 |
Friess H, Guo XZ, Berberat P, Graber HU, Zimmermann A, Korc M, Büchler MW. Reduced KAI1 expression in pancreatic cancer is associated with lymph node and distant metastases. International Journal of Cancer. Journal International Du Cancer. 79: 349-55. PMID 9699525 DOI: 10.1002/(Sici)1097-0215(19980821)79:4<349::Aid-Ijc7>3.0.Co;2-V |
0.317 |
|
| 1998 |
Ishiwata T, Friess H, Büchler MW, Lopez ME, Korc M. Characterization of keratinocyte growth factor and receptor expression in human pancreatic cancer. The American Journal of Pathology. 153: 213-22. PMID 9665482 DOI: 10.1016/S0002-9440(10)65562-9 |
0.538 |
|
| 1998 |
Kornmann M, Ishiwata T, Itakura J, Tangvoranuntakul P, Beger HG, Korc M. Increased cyclin D1 in human pancreatic cancer is associated with decreased postoperative survival Oncology. 55: 363-369. PMID 9663429 DOI: 10.1159/000011879 |
0.375 |
|
| 1998 |
Ebert M, Kasper HU, Hernberg S, Friess H, Büchler MW, Roessner A, Korc M, Malfertheiner P. Overexpression of platelet-derived growth factor (PDGF) B chain and type beta PDGF receptor in human chronic pancreatitis. Digestive Diseases and Sciences. 43: 567-74. PMID 9539653 DOI: 10.1023/A:1018867209170 |
0.358 |
|
| 1998 |
Kleeff J, Korc M. Up-regulation of transforming growth factor (TGF)-beta receptors by TGF-beta1 in COLO-357 cells. The Journal of Biological Chemistry. 273: 7495-500. PMID 9516449 DOI: 10.1074/Jbc.273.13.7495 |
0.332 |
|
| 1998 |
Wagner M, Lopez ME, Cahn M, Korc M. Suppression of fibroblast growth factor receptor signaling inhibits pancreatic cancer growth in vitro and in vivo. Gastroenterology. 114: 798-807. PMID 9516401 DOI: 10.1016/S0016-5085(98)70594-3 |
0.484 |
|
| 1998 |
Friess H, Lu Z, Riesle E, Uhl W, Bründler AM, Horvath L, Gold LI, Korc M, Büchler MW. Enhanced expression of TGF-betas and their receptors in human acute pancreatitis. Annals of Surgery. 227: 95-104. PMID 9445116 DOI: 10.1097/00000658-199801000-00014 |
0.322 |
|
| 1998 |
Kornmann M, Arber N, Korc M. Inhibition of basal and mitogen-stimulated pancreatic cancer cell growth by cyclin D1 antisense is associated with loss of tumorigenicity and potentiation of cytotoxicity to cisplatinum. The Journal of Clinical Investigation. 101: 344-52. PMID 9435306 DOI: 10.1172/Jci1323 |
0.431 |
|
| 1998 |
Korc M. Role of Growth Factors in Pancreatic Cancer Surgical Oncology Clinics of North America. 7: 25-41. DOI: 10.1016/S1055-3207(18)30283-7 |
0.475 |
|
| 1998 |
Friess H, Duarte R, Kleeff J, Fukuda A, Tang W, Graber H, Schilling M, Zimmermann A, Korc M, Büchler MW. The plasminogen activator/plasmin system is up-regulated after acute necrotizing pancreatitis in human beings Surgery. 124: 79-86. DOI: 10.1016/S0039-6060(98)70078-9 |
0.341 |
|
| 1998 |
Ebert M, Yokoyama M, Ishiwata T, Friess H, Büchler M, Malfertheiner P, Korc M. Alteration of fibroblast growth factor expression following acute pancreatitis Gastroenterology. 114: A455. DOI: 10.1016/S0016-5085(98)81838-6 |
0.346 |
|
| 1997 |
Lu Z, Friess H, Graber HU, Guo X, Schilling M, Zimmermann A, Korc M, Büchler MW. Presence of two signaling TGF-beta receptors in human pancreatic cancer correlates with advanced tumor stage. Digestive Diseases and Sciences. 42: 2054-63. PMID 9365135 DOI: 10.1023/A:1018814416903 |
0.427 |
|
| 1997 |
Ishiwata T, Bergmann U, Kornmann M, Lopez M, Beger HG, Korc M. Altered expression of insulin-like growth factor II receptor in human pancreatic cancer. Pancreas. 15: 367-73. PMID 9361090 DOI: 10.1097/00006676-199711000-00006 |
0.464 |
|
| 1997 |
Kornmann M, Ishiwata T, Beger HG, Korc M. Fibroblast growth factor-5 stimulates mitogenic signaling and is overexpressed in human pancreatic cancer: evidence for autocrine and paracrine actions. Oncogene. 15: 1417-24. PMID 9333017 DOI: 10.1038/Sj.Onc.1201307 |
0.489 |
|
| 1997 |
Funatomi H, Itakura J, Ishiwata T, Pastan I, Thompson SA, Johnson GR, Korc M. Amphiregulin antisense oligonucleotide inhibits the growth of T3M4 human pancreatic cancer cells and sensitizes the cells to EGF receptor-targeted therapy. International Journal of Cancer. 72: 512-7. PMID 9247297 DOI: 10.1002/(Sici)1097-0215(19970729)72:3<512::Aid-Ijc21>3.0.Co;2-C |
0.489 |
|
| 1997 |
Cantero D, Friess H, Deflorin J, Zimmermann A, Bründler MA, Riesle E, Korc M, Büchler MW. Enhanced expression of urokinase plasminogen activator and its receptor in pancreatic carcinoma. British Journal of Cancer. 75: 388-95. PMID 9020484 DOI: 10.1038/Bjc.1997.63 |
0.463 |
|
| 1997 |
Deflorin J, Friess H, Schobinger S, Bründler M, Schilling M, Naef M, Korc M, Büchler MW. Overexpression of the Epidermal Growth Factor Receptor Family in Gastric Cancer Suggests a Role in Tumor Pathogenesis Digestive Surgery. 14: 252-259. DOI: 10.1159/000172554 |
0.322 |
|
| 1996 |
Bergmann U, Funatomi H, Kornmann M, Ishiwata T, Beger H, Korc M. Insulin-like growth factor II activates mitogenic signaling in pancreatic cancer cells via IRS-1. International Journal of Oncology. 9: 487-92. PMID 21541539 DOI: 10.3892/ijo.9.3.487 |
0.362 |
|
| 1996 |
Wagner M, Cao T, Lopez ME, Hope C, van Nostrand K, Kobrin MS, Fan HU, Büchler MW, Korc M. Expression of a truncated EGF receptor is associated with inhibition of pancreatic cancer cell growth and enhanced sensitivity to cisplatinum. International Journal of Cancer. 68: 782-7. PMID 8980184 DOI: 10.1002/(Sici)1097-0215(19961211)68:6<782::Aid-Ijc16>3.0.Co;2-2 |
0.436 |
|
| 1996 |
Friess H, Berberat P, Schilling M, Kunz J, Korc M, Büchler MW. Pancreatic cancer: the potential clinical relevance of alterations in growth factors and their receptors. Journal of Molecular Medicine (Berlin, Germany). 74: 35-42. PMID 8834768 DOI: 10.1007/BF00202070 |
0.451 |
|
| 1996 |
Lopez ME, Kobrin MS, Moriai T, Yokoyama M, Friess H, Büchler M, Korc M. Single-strand conformation polymorphism analysis of the epidermal growth factor receptor at codon 497. Pancreas. 12: 216-20. PMID 8830326 DOI: 10.1097/00006676-199604000-00002 |
0.414 |
|
| 1996 |
Baldwin RL, Kobrin MS, Tran T, Pastan I, Korc M. Cytotoxic effects of TGF-α-Pseudomonas exotoxin A fusion protein in human pancreatic carcinoma cells Pancreas. 13: 16-21. PMID 8783329 DOI: 10.1097/00006676-199607000-00002 |
0.491 |
|
| 1996 |
Baldwin RL, Friess H, Yokoyama M, Lopez ME, Kobrin MS, Büchler MW, Korc M. Attenuated ALK5 receptor expression in human pancreatic cancer: Correlation with resistance to growth inhibition International Journal of Cancer. 67: 283-288. PMID 8760600 DOI: 10.1002/(Sici)1097-0215(19960717)67:2<283::Aid-Ijc21>3.0.Co;2-B |
0.356 |
|
| 1996 |
Visser CJ, de Weger RA, van Blokland WT, Seifert-Bock I, Kobrin MS, Korc M, Woutersen RA. Epidermal growth factor receptor expression in pancreatic lesions induced in the rat by azaserine. British Journal of Cancer. 74: 92-8. PMID 8679465 DOI: 10.1038/Bjc.1996.321 |
0.326 |
|
| 1996 |
Visser CJ, Bruggink AH, Korc M, Kobrin MS, de Weger RA, Seifert-Bock I, van Blokland WT, van Garderen-Hoetmer A, Woutersen RA. Overexpression of transforming growth factor-alpha and epidermal growth factor receptor, but not epidermal growth factor, in exocrine pancreatic tumours in hamsters. Carcinogenesis. 17: 779-85. PMID 8625491 DOI: 10.1093/Carcin/17.4.779 |
0.338 |
|
| 1996 |
Estival A, Monzat V, Miquel K, Gaubert F, Hollande E, Korc M, Vaysse N, Clemente F. Differential regulation of fibroblast growth factor (FGF) receptor-1 mRNA and protein by two molecular forms of basic FGF. Modulation of FGFR-1 mRNA stability. Journal of Biological Chemistry. 271: 5663-5670. PMID 8621430 DOI: 10.1074/Jbc.271.10.5663 |
0.348 |
|
| 1996 |
Naef M, Yokoyama M, Friess H, Büchler MW, Korc M. Co-expression of heparin-binding EGF-like growth factor and related peptides in human gastric carcinoma. International Journal of Cancer. 66: 315-21. PMID 8621250 DOI: 10.1002/(Sici)1097-0215(19960503)66:3<315::Aid-Ijc8>3.0.Co;2-1 |
0.373 |
|
| 1996 |
Bergmann U, Funatomi H, Kornmann M, Beger HG, Korc M. Increased expression of insulin receptor substrate-1 in human pancreatic cancer. Biochemical and Biophysical Research Communications. 220: 886-90. PMID 8607861 DOI: 10.1006/Bbrc.1996.0500 |
0.41 |
|
| 1995 |
Ebert M, Yokoyama M, Friess H, Kobrin MS, Büchler MW, Korc M. Induction of platelet-derived growth factor A and B chains and over-expression of their receptors in human pancreatic cancer. International Journal of Cancer. 62: 529-35. PMID 7665222 DOI: 10.1002/Ijc.2910620507 |
0.43 |
|
| 1995 |
Ebert M, Friess H, Büchler MW, Korc M. Differential distribution of human epidermal growth factor receptor family in acute pancreatitis. Digestive Diseases and Sciences. 40: 2134-42. PMID 7587780 DOI: 10.1007/Bf02208997 |
0.395 |
|
| 1995 |
Siddiqi I, Funatomi H, Kobrin MS, Friess H, Büchler MW, Korc M. Increased expression of keratinocyte growth factor in human pancreatic cancer. Biochemical and Biophysical Research Communications. 215: 309-15. PMID 7575607 DOI: 10.1006/Bbrc.1995.2467 |
0.489 |
|
| 1995 |
Friess H, Büchler M, Hofbauer B, Uhl W, Gold L, Korc M. Overexpression of transforming growth factor βs and their receptors in acute pancreatitis in humans Gastroenterology. 108: A354. DOI: 10.1016/0016-5085(95)24075-6 |
0.322 |
|
| 1995 |
Ebert M, Yokoyama M, Friess H, Büchler M, Korc M. Overexpression of platelet-derived growth factor (PDGF) receptors in human pancreatic ductal adenocarcinoma Gastroenterology. 108: A351. DOI: 10.1016/0016-5085(95)24062-4 |
0.313 |
|
| 1995 |
Ebert M, Friess H, Korc M, Büchler M. Altered expression of the human epidermal growth factor (HER) family in acute pancreatitis suggests a prominent role for HER-1 Gastroenterology. 108: A351. DOI: 10.1016/0016-5085(95)24060-8 |
0.338 |
|
| 1995 |
Deflorin J, Friess H, Schmid R, Horvath L, Korc M, Adler G, Büchler M. Enhanced expression of apoptotic factors implicate a role in human pancreatic cancer Gastroenterology. 108: A349. DOI: 10.1016/0016-5085(95)24055-1 |
0.418 |
|
| 1994 |
Friess H, Yamanaka Y, Büchler M, Kobrin MS, Tahara E, Korc M. Cripto, a member of the epidermal growth factor family, is over-expressed in human pancreatic cancer and chronic pancreatitis. International Journal of Cancer. 56: 668-74. PMID 8314343 DOI: 10.1002/Ijc.2910560511 |
0.531 |
|
| 1994 |
Friess H, Yamanaka Y, Büchler M, Ebert M, Beger HG, Gold LI, Korc M. Enhanced expression of transforming growth factor beta isoforms in pancreatic cancer correlates with decreased survival. Gastroenterology. 105: 1846-56. PMID 8253361 DOI: 10.1016/0016-5085(93)91084-U |
0.375 |
|
| 1994 |
Kobrin MS, Funatomi H, Friess H, Buchler MW, Stathis P, Korc M. Induction and expression of heparin-binding EGF-like growth factor in human pancreatic cancer. Biochemical and Biophysical Research Communications. 202: 1705-9. PMID 8060360 DOI: 10.1006/bbrc.1994.2131 |
0.516 |
|
| 1994 |
Korc M, Friess H, Yamanaka Y, Kobrin MS, Buchler M, Beger HG. Chronic pancreatitis is associated with increased concentrations of epidermal growth factor receptor, transforming growth factor alpha, and phospholipase C gamma. Gut. 35: 1468-73. PMID 7959207 DOI: 10.1136/Gut.35.10.1468 |
0.381 |
|
| 1994 |
Moriai T, Kobrin MS, Hope C, Speck L, Korc M. A variant epidermal growth factor receptor exhibits altered type alpha transforming growth factor binding and transmembrane signaling. Proceedings of the National Academy of Sciences of the United States of America. 91: 10217-21. PMID 7937865 DOI: 10.1073/Pnas.91.21.10217 |
0.304 |
|
| 1994 |
Korc M, Friess H, Kobrin MS, Ebert M, Büchler MW. Growth Factors in Human Pancreatic Cancer: Update on the Role of the Epidermal Growth Factor Receptor Digestive Surgery. 11: 147-149. DOI: 10.1159/000172245 |
0.4 |
|
| 1993 |
Casey G, Yamanaka Y, Friess H, Kobrin MS, Lopez ME, Buchler M, Beger HG, Korc M. p53 mutations are common in pancreatic cancer and are absent in chronic pancreatitis. Cancer Letters. 69: 151-60. PMID 8513440 DOI: 10.1016/0304-3835(93)90168-9 |
0.342 |
|
| 1993 |
Moriai T, Kobrin MS, Korc M. Cloning of a variant epidermal growth factor receptor. Biochemical and Biophysical Research Communications. 191: 1034-9. PMID 8466482 DOI: 10.1006/Bbrc.1993.1321 |
0.383 |
|
| 1993 |
Baldwin RL, Korc M. Growth inhibition of human pancreatic carcinoma cells by transforming growth factor beta-1. Growth Factors (Chur, Switzerland). 8: 23-34. PMID 8383514 DOI: 10.3109/08977199309029131 |
0.369 |
|
| 1993 |
Yamanaka Y, Friess H, Kobrin MS, Büchler M, Kunz J, Beger HG, Korc M. Overexpression of HER2/neu oncogene in human pancreatic carcinoma. Human Pathology. 24: 1127-34. PMID 8104858 DOI: 10.1016/0046-8177(93)90194-L |
0.338 |
|
| 1992 |
Korc M. Growth factors and pancreatic cancer. International Journal of Pancreatology : Official Journal of the International Association of Pancreatology. 9: 87-91. PMID 1744452 DOI: 10.1007/Bf02925583 |
0.456 |
|
| 1992 |
Korc M, Chandrasekar B, Yamanaka Y, Friess H, Buchier M, Beger HG. Overexpression of the epidermal growth factor receptor in human pancreatic cancer is associated with concomitant increases in the levels of epidermal growth factor and transforming growth factor alpha. The Journal of Clinical Investigation. 90: 1352-60. PMID 1401070 DOI: 10.1172/Jci116001 |
0.416 |
|
| 1991 |
Korc M. Potential role of the epidermal growth factor receptor in human pancreatic cancer. International Journal of Pancreatology : Official Journal of the International Association of Pancreatology. 7: 71-81. PMID 2081930 DOI: 10.1007/Bf02924222 |
0.377 |
|
| 1990 |
Garewal H, Meltzer P, Trent J, Prabhala R, Sampliner R, Korc M. Epidermal growth factor receptor overexpression and trisomy 7 in a case of Barrett's esophagus. Digestive Diseases and Sciences. 35: 1115-20. PMID 2390926 DOI: 10.1007/Bf01537584 |
0.301 |
|
| 1990 |
Raitano AB, Scuderi P, Korc M. Binding and biological effects of tumor necrosis factor and gamma interferon in human pancreatic carcinoma cells. Pancreas. 5: 267-77. PMID 2111548 DOI: 10.1097/00006676-199005000-00005 |
0.33 |
|
| 1987 |
Smith JJ, Derynck R, Korc M. Production of transforming growth factor alpha in human pancreatic cancer cells: evidence for a superagonist autocrine cycle. Proceedings of the National Academy of Sciences of the United States of America. 84: 7567-70. PMID 3499610 DOI: 10.1073/Pnas.84.21.7567 |
0.351 |
|
| 1987 |
Bell C, Rosenblum M, Harsh G, Korc M, Meltzer P, Trent J. 12 Correlation of chromosome 7 alterations with expression of epidermal growth factor receptor (EGF) in human glial and pancreatic carcinomas Cancer Genetics and Cytogenetics. 28: 31. DOI: 10.1016/0165-4608(87)90291-3 |
0.306 |
|
| 1986 |
Korc M, Meltzer P, Trent J. Enhanced expression of epidermal growth factor receptor correlates with alterations of chromosome 7 in human pancreatic cancer Proceedings of the National Academy of Sciences of the United States of America. 83: 5141-5144. PMID 3014534 DOI: 10.1073/Pnas.83.14.5141 |
0.352 |
|
| 1986 |
Korc M, Padilla J, Grosso D. Epidermal growth factor inhibits the proliferation of a human endometrial carcinoma cell line Journal of Clinical Endocrinology and Metabolism. 62: 874-880. PMID 3007558 DOI: 10.1210/JCEM-62-5-874 |
0.303 |
|
| 1985 |
Korc M, Magun BE. Binding and processing of epidermal growth factor in Panc-I human pancreatic carcinoma cells. Life Sciences. 36: 1849-1855. PMID 2985903 DOI: 10.1016/0024-3205(85)90158-4 |
0.328 |
|
| 1984 |
Korc M, Matrisian LM, Magun BE. Cytosolic calcium regulates epidermal growth factor endocytosis in rat pancreas and cultured fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 81: 461-5. PMID 6320188 DOI: 10.1073/Pnas.81.2.461 |
0.306 |
|
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