David M. Reif - Publications

Affiliations: 
North Carolina State University, Raleigh, NC 
Area:
Bioinformatics, Computational Toxicology, Environmental Health Sciences

106 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Green AJ, Truong L, Thunga P, Leong C, Hancock M, Tanguay RL, Reif DM. Deep autoencoder-based behavioral pattern recognition outperforms standard statistical methods in high-dimensional zebrafish studies. Biorxiv : the Preprint Server For Biology. PMID 37745446 DOI: 10.1101/2023.09.13.557544  0.621
2022 Thunga P, Truong L, Rericha Y, Du J, Morshead M, Tanguay RL, Reif DM. Utilizing a Population-Genetic Framework to Test for Gene-Environment Interactions between Zebrafish Behavior and Chemical Exposure. Toxics. 10. PMID 36548602 DOI: 10.3390/toxics10120769  0.614
2022 Roell K, Koval LE, Boyles R, Patlewicz G, Ring C, Rider CV, Ward-Caviness C, Reif DM, Jaspers I, Fry RC, Rager JE. Development of the InTelligence And Machine LEarning (TAME) Toolkit for Introductory Data Science, Chemical-Biological Analyses, Predictive Modeling, and Database Mining for Environmental Health Research. Frontiers in Toxicology. 4: 893924. PMID 35812168 DOI: 10.3389/ftox.2022.893924  0.747
2022 Wallis DJ, La Du J, Thunga P, Elson D, Truong L, Kolluri SK, Tanguay RL, Reif DM. Leveraging a High-Throughput Screening Method to Identify Mechanisms of Individual Susceptibility Differences in a Genetically Diverse Zebrafish Model. Frontiers in Toxicology. 4: 846221. PMID 35573279 DOI: 10.3389/ftox.2022.846221  0.618
2022 Fleming J, Marvel SW, Supak S, Motsinger-Reif AA, Reif DM. ToxPi*GIS Toolkit: creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS. Journal of Exposure Science & Environmental Epidemiology. PMID 35474345 DOI: 10.1038/s41370-022-00433-w  0.714
2022 Thessen AE, Marvel S, Achenbach JC, Fischer S, Haendel MA, Hayward K, Klüver N, Könemann S, Legradi J, Lein P, Leong C, Mylroie JE, Padilla S, Perone D, Planchart A, ... ... Reif D, et al. Implementation of Zebrafish Ontologies for Toxicology Screening. Frontiers in Toxicology. 4: 817999. PMID 35387429 DOI: 10.3389/ftox.2022.817999  0.787
2022 Truong L, Rericha Y, Thunga P, Marvel S, Wallis D, Simonich MT, Field JA, Cao D, Reif DM, Tanguay RL. Systematic developmental toxicity assessment of a structurally diverse library of PFAS in zebrafish. Journal of Hazardous Materials. 431: 128615. PMID 35263707 DOI: 10.1016/j.jhazmat.2022.128615  0.803
2021 Thunga P, Truong L, Tanguay RL, Reif DM. Concurrent Evaluation of Mortality and Behavioral Responses: A Fast and Efficient Testing Approach for High-Throughput Chemical Hazard Identification. Frontiers in Toxicology. 3: 670496. PMID 35295121 DOI: 10.3389/ftox.2021.670496  0.643
2021 Fleming J, Marvel SW, Motsinger-Reif AA, Reif DM. ToxPi*GIS Toolkit: Creating, viewing, and sharing integrative visualizations for geospatial data using ArcGIS. Medrxiv : the Preprint Server For Health Sciences. PMID 34671776 DOI: 10.1101/2021.10.08.21264756  0.718
2021 Akhtari FS, Green AJ, Small GW, Havener TM, House JS, Roell KR, Reif DM, McLeod HL, Wiltshire T, Motsinger-Reif AA. High-throughput screening and genome-wide analyses of 44 anticancer drugs in the 1000 Genomes cell lines reveals an association of the NQO1 gene with the response of multiple anticancer drugs. Plos Genetics. 17: e1009732. PMID 34437536 DOI: 10.1371/journal.pgen.1009732  0.71
2021 Green AJ, Mohlenkamp MJ, Das J, Chaudhari M, Truong L, Tanguay RL, Reif DM. Leveraging high-throughput screening data, deep neural networks, and conditional generative adversarial networks to advance predictive toxicology. Plos Computational Biology. 17: e1009135. PMID 34214078 DOI: 10.1371/journal.pcbi.1009135  0.622
2021 Wallis DJ, Truong L, La Du J, Tanguay RL, Reif DM. Uncovering Evidence for Endocrine-Disrupting Chemicals That Elicit Differential Susceptibility through Gene-Environment Interactions. Toxics. 9. PMID 33917455 DOI: 10.3390/toxics9040077  0.594
2021 Marvel SW, House JS, Wheeler M, Song K, Zhou YH, Wright FA, Chiu WA, Rusyn I, Motsinger-Reif A, Reif DM. The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: Monitoring County-Level Vulnerability Using Visualization, Statistical Modeling, and Machine Learning. Environmental Health Perspectives. 129: 17701. PMID 33400596 DOI: 10.1289/EHP8690  0.68
2020 Truong L, Marvel S, Reif DM, Thomas D, Pande P, Dasgupta S, Simonich MT, Waters KM, Tanguay RL. The multi-dimensional embryonic zebrafish platform predicts flame retardant bioactivity. Reproductive Toxicology (Elmsford, N.Y.). PMID 32827657 DOI: 10.1016/J.Reprotox.2020.08.007  0.809
2020 Marvel S, House J, Wheeler M, Song K, Zhou Y, Wright F, Chiu W, Rusyn I, Motsinger-Reif A, Reif DM. The COVID-19 Pandemic Vulnerability Index (PVI) Dashboard: monitoring county level vulnerability. Medrxiv : the Preprint Server For Health Sciences. PMID 32817964 DOI: 10.1101/2020.08.10.20169649  0.699
2020 Phelps DW, Fletcher AA, Rodriguez-Nunez I, Balik-Meisner MR, Tokarz DA, Reif DM, Germolec DR, Yoder JA. assessment of respiratory burst inhibition by xenobiotic exposure using larval zebrafish. Journal of Immunotoxicology. 17: 94-104. PMID 32407153 DOI: 10.1080/1547691X.2020.1748772  0.779
2020 Bhandari S, Lewis PGT, Craft E, Marvel SW, Reif DM, Chiu WA. HGBEnviroScreen: Enabling Community Action through Data Integration in the Houston-Galveston-Brazoria Region. International Journal of Environmental Research and Public Health. 17. PMID 32053902 DOI: 10.3390/Ijerph17041130  0.733
2019 To KT, Truong L, Edwards S, Tanguay RL, Reif DM. Multivariate modeling of engineered nanomaterial features associated with developmental toxicity. Nanoimpact. 16. PMID 32133425 DOI: 10.1016/J.Impact.2019.100185  0.738
2019 Kosnik MB, Strickland JD, Marvel SW, Wallis DJ, Wallace K, Richard AM, Reif DM, Shafer TJ. Concentration-response evaluation of ToxCast compounds for multivariate activity patterns of neural network function. Archives of Toxicology. PMID 31822930 DOI: 10.1007/S00204-019-02636-X  0.783
2019 Gillera SEA, Marinello WP, Horman BM, Phillips AL, Ruis MT, Stapleton HM, Reif DM, Patisaul HB. Sex-specific effects of perinatal FireMaster® 550 (FM 550) exposure on socioemotional behavior in prairie voles. Neurotoxicology and Teratology. 106840. PMID 31730801 DOI: 10.1016/J.Ntt.2019.106840  0.315
2019 Roell KR, Havener TM, Reif DM, Jack J, McLeod HL, Wiltshire T, Motsinger-Reif AA. Synergistic Chemotherapy Drug Response Is a Genetic Trait in Lymphoblastoid Cell Lines. Frontiers in Genetics. 10: 829. PMID 31681399 DOI: 10.3389/Fgene.2019.00829  0.72
2019 Kosnik MB, Planchart A, Marvel SW, Reif DM, Mattingly CJ. Integration of curated and high-throughput screening data to elucidate environmental influences on disease pathways. Computational Toxicology (Amsterdam, Netherlands). 12. PMID 31453412 DOI: 10.1016/J.Comtox.2019.100094  0.804
2019 Burnett SD, Blanchette AD, Grimm FA, House JS, Reif DM, Wright FA, Chiu WA, Rusyn I. Population-based toxicity screening in human induced pluripotent stem cell-derived cardiomyocytes. Toxicology and Applied Pharmacology. 114711. PMID 31425687 DOI: 10.1016/J.Taap.2019.114711  0.415
2019 Kosnik MB, Reif DM. Determination of chemical-disease risk values to prioritize connections between environmental factors, genetic variants, and human diseases. Toxicology and Applied Pharmacology. 379: 114674. PMID 31323264 DOI: 10.1016/J.Taap.2019.114674  0.666
2019 Truong L, Zaikova T, Baldock BL, Balik-Meisner M, To K, Reif DM, Kennedy ZC, Hutchison JE, Tanguay RL. Systematic determination of the relationship between nanoparticle core diameter and toxicity for a series of structurally analogous gold nanoparticles in zebrafish. Nanotoxicology. 1-15. PMID 30938251 DOI: 10.1080/17435390.2019.1592259  0.759
2019 Kosnik MB, Reif DM, Lobdell DT, Astell-Burt T, Feng X, Hader JD, Hoppin JA. Associations between access to healthcare, environmental quality, and end-stage renal disease survival time: Proportional-hazards models of over 1,000,000 people over 14 years. Plos One. 14: e0214094. PMID 30897121 DOI: 10.1371/Journal.Pone.0214094  0.601
2018 Baptissart M, Lamb HE, To K, Bradish C, Tehrani J, Reif D, Cowley M. Neonatal mice exposed to a high-fat diet influence the behaviour of their nursing dam. Proceedings. Biological Sciences. 285. PMID 30429298 DOI: 10.1098/Rspb.2018.1237  0.577
2018 Balik-Meisner M, Truong L, Scholl EH, La Du JK, Tanguay RL, Reif DM. Elucidating Gene-by-Environment Interactions Associated with Differential Susceptibility to Chemical Exposure. Environmental Health Perspectives. 126: 067010. PMID 29968567 DOI: 10.1289/Ehp2662  0.785
2018 To KT, Fry RC, Reif DM. Characterizing the effects of missing data and evaluating imputation methods for chemical prioritization applications using ToxPi. Biodata Mining. 11: 10. PMID 29942350 DOI: 10.1186/S13040-018-0169-5  0.671
2018 Mahapatra D, Franzosa JA, Roell K, Kuenemann MA, Houck KA, Reif DM, Fourches D, Kullman SW. Confirmation of high-throughput screening data and novel mechanistic insights into VDR-xenobiotic interactions by orthogonal assays. Scientific Reports. 8: 8883. PMID 29891985 DOI: 10.1038/S41598-018-27055-3  0.742
2018 Marvel SW, To K, Grimm FA, Wright FA, Rusyn I, Reif DM. ToxPi Graphical User Interface 2.0: Dynamic exploration, visualization, and sharing of integrated data models. Bmc Bioinformatics. 19: 80. PMID 29506467 DOI: 10.1186/S12859-018-2089-2  0.773
2018 Balik-Meisner M, Truong L, Scholl EH, Tanguay RL, Reif DM. Population genetic diversity in zebrafish lines. Mammalian Genome : Official Journal of the International Mammalian Genome Society. PMID 29368091 DOI: 10.1007/S00335-018-9735-X  0.773
2018 Kosnik M, Reif D, Lobdell D, Astell-Burt T, Feng X, Hader JD, Hoppin J. Does Overall Environmental Quality Affect End-Stage Renal Disease Survival? Isee Conference Abstracts. 2018. DOI: 10.1289/isesisee.2018.p01.2070  0.553
2017 Chiu WA, Guyton KZ, Martin MT, Reif DM, Rusyn I. Use of high-throughput in vitro toxicity screening data in cancer hazard evaluations by IARC Monograph Working Groups. Altex. PMID 28738424 DOI: 10.14573/Altex.1703231  0.346
2017 Knecht AL, Truong L, Marvel SW, Reif DM, Garcia A, Lu C, Simonich MT, Teeguarden JG, Tanguay RL. Transgenerational inheritance of neurobehavioral and physiological deficits from developmental exposure to benzo[a]pyrene in zebrafish. Toxicology and Applied Pharmacology. PMID 28583304 DOI: 10.1016/J.Taap.2017.05.033  0.771
2017 Roell KR, Reif DM, Motsinger-Reif AA. An Introduction to Terminology and Methodology of Chemical Synergy-Perspectives from Across Disciplines. Frontiers in Pharmacology. 8: 158. PMID 28473769 DOI: 10.3389/Fphar.2017.00158  0.729
2017 Zhang G, Truong L, Tanguay RL, Reif DM. A New Statistical Approach to Characterize Chemical-Elicited Behavioral Effects in High-Throughput Studies Using Zebrafish. Plos One. 12: e0169408. PMID 28099482 DOI: 10.1371/Journal.Pone.0169408  0.771
2016 Scott Chialvo CH, Che R, Reif D, Motsinger-Reif A, Reed LK. Eigenvector metabolite analysis reveals dietary effects on the association among metabolite correlation patterns, gene expression, and phenotypes. Metabolomics : Official Journal of the Metabolomic Society. 12. PMID 28845148 DOI: 10.1007/S11306-016-1117-3  0.335
2016 Watson AT, Planchart A, Mattingly CJ, Winkler C, Reif DM, Kullman SW. Embryonic Exposure to TCDD Impacts Osteogenesis of the Axial Skeleton in Japanese medaka, Oryzias latipes. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 28077779 DOI: 10.1093/Toxsci/Kfw229  0.329
2016 Grimm FA, Iwata Y, Sirenko O, Chappell GA, Wright FA, Reif DM, Braisted J, Gerhold DL, Yeakley JM, Shepard P, Seligmann B, Roy T, Boogaard PJ, Ketelslegers HB, Rohde AM, et al. A chemical-biological similarity-based grouping of complex substances as a prototype approach for evaluating chemical alternatives. Green Chemistry : An International Journal and Green Chemistry Resource : Gc. 18: 4407-4419. PMID 28035192 DOI: 10.1039/C6Gc01147K  0.402
2016 Kollitz EM, Zhang G, Hawkins MB, Whitfield GK, Reif DM, Kullman SW. Evolutionary and Functional Diversification of the Vitamin D Receptor-Lithocholic Acid Partnership. Plos One. 11: e0168278. PMID 27942020 DOI: 10.1371/Journal.Pone.0168278  0.595
2016 Zhang G, Roell KR, Truong L, Tanguay RL, Reif DM. A data-driven weighting scheme for multivariate phenotypic endpoints recapitulates zebrafish developmental cascades. Toxicology and Applied Pharmacology. PMID 27884602 DOI: 10.1016/J.Taap.2016.11.010  0.798
2016 Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S, Wambaugh J, Setzer RW, Kothiya P, Phuong J, Filer D, Smith D, Reif D, Rotroff D, et al. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27605417 DOI: 10.1093/Toxsci/Kfw148  0.743
2016 Planchart A, Mattingly CJ, Allen D, Ceger P, Casey W, Hinton D, Kanungo J, Kullman SW, Tal T, Bondesson M, Burgess SM, Sullivan C, Kim C, Behl M, Padilla S, ... Reif DM, et al. Advancing toxicology research using in vivo high throughput toxicology with small fish models. Altex. PMID 27328013 DOI: 10.14573/Altex.1601281  0.338
2016 Judson R, Houck K, Martin M, Richard AM, Knudsen TB, Shah I, Little S, Wambaugh J, Setzer RW, Kothya P, Phuong J, Filer D, Smith D, Reif D, Rotroff D, et al. Analysis of the Effects of Cell Stress and Cytotoxicity on In Vitro Assay Activity Across a Diverse Chemical and Assay Space. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 27208079 DOI: 10.1093/Toxsci/Kfw092  0.769
2016 Grondin CJ, Davis AP, Wiegers TC, King BL, Wiegers JA, Reif DM, Hoppin JA, Mattingly CJ. Advancing Exposure Science through Chemical Data Curation and Integration in the Comparative Toxicogenomics Database. Environmental Health Perspectives. PMID 27170236 DOI: 10.1289/Ehp174  0.383
2016 Zhang G, Marvel S, Truong L, Tanguay RL, Reif DM. Aggregate Entropy Scoring for Quantifying Activity across Endpoints with Irregular Correlation Structure. Reproductive Toxicology (Elmsford, N.Y.). PMID 27132190 DOI: 10.1016/J.Reprotox.2016.04.012  0.789
2016 Auerbach S, Filer D, Reif D, Walker V, Holloway AC, Schlezinger J, Srinivasan S, Svoboda D, Judson R, Bucher JR, Thayer KA. Prioritizing Environmental Chemicals for Obesity and Diabetes Outcomes Research: A Screening Approach Using ToxCast High Throughput Data. Environmental Health Perspectives. PMID 26978842 DOI: 10.1289/Ehp.1510456  0.755
2015 Shah I, Setzer RW, Jack J, Houck KA, Judson RS, Knudsen TB, Liu J, Martin MT, Reif DM, Richard AM, Thomas RS, Crofton KM, Dix DJ, Kavlock RJ. Using ToxCast™ Data to Reconstruct Dynamic Cell State Trajectories and Estimate Toxicological Points of Departure. Environmental Health Perspectives. PMID 26473631 DOI: 10.1289/Ehp.1409029  0.315
2015 Rebuli ME, Camacho L, Adonay ME, Reif DM, Aylor DL, Patisaul HB. Impact of Low Dose Oral Exposure to Bisphenol A (BPA) on Juvenile and Adult Rat Exploratory and Anxiety Behavior: A CLARITY-BPA Consortium Study. Toxicological Sciences : An Official Journal of the Society of Toxicology. PMID 26209558 DOI: 10.1093/Toxsci/Kfv163  0.349
2015 Rovida C, Asakura S, Daneshian M, Hofman-Huether H, Leist M, Meunier L, Reif D, Rossi A, Schmutz M, Valentin JP, Zurlo J, Hartung T. Toxicity testing in the 21st century beyond environmental chemicals. Altex. 32: 171-81. PMID 26168280 DOI: 10.14573/Altex.1506201  0.344
2015 Reif DM, Truong L, Mandrell D, Marvel S, Zhang G, Tanguay RL. High-throughput characterization of chemical-associated embryonic behavioral changes predicts teratogenic outcomes. Archives of Toxicology. PMID 26126630 DOI: 10.1007/S00204-015-1554-1  0.786
2015 Kollitz EM, Zhang G, Hawkins MB, Whitfield GK, Reif DM, Kullman SW. Molecular cloning, functional characterization, and evolutionary analysis of vitamin D receptors isolated from basal vertebrates. Plos One. 10: e0122853. PMID 25855982 DOI: 10.1371/Journal.Pone.0122853  0.612
2015 Ducharme NA, Reif DM, Gustafsson JA, Bondesson M. Comparison of toxicity values across zebrafish early life stages and mammalian studies: Implications for chemical testing. Reproductive Toxicology (Elmsford, N.Y.). 55: 3-10. PMID 25261610 DOI: 10.1016/J.Reprotox.2014.09.005  0.405
2014 Filer D, Patisaul HB, Schug T, Reif D, Thayer K. Test driving ToxCast: endocrine profiling for 1858 chemicals included in phase II. Current Opinion in Pharmacology. 19: 145-52. PMID 25460227 DOI: 10.1016/J.Coph.2014.09.021  0.779
2014 Huang R, Sakamuru S, Martin MT, Reif DM, Judson RS, Houck KA, Casey W, Hsieh JH, Shockley KR, Ceger P, Fostel J, Witt KL, Tong W, Rotroff DM, Zhao T, et al. Profiling of the Tox21 10K compound library for agonists and antagonists of the estrogen receptor alpha signaling pathway. Scientific Reports. 4: 5664. PMID 25012808 DOI: 10.1038/Srep05664  0.356
2014 Rotroff DM, Martin MT, Dix DJ, Filer DL, Houck KA, Knudsen TB, Sipes NS, Reif DM, Xia M, Huang R, Judson RS. Predictive endocrine testing in the 21st century using in vitro assays of estrogen receptor signaling responses. Environmental Science & Technology. 48: 8706-16. PMID 24960280 DOI: 10.1021/Es502676E  0.78
2014 Kleinstreuer NC, Yang J, Berg EL, Knudsen TB, Richard AM, Martin MT, Reif DM, Judson RS, Polokoff M, Dix DJ, Kavlock RJ, Houck KA. Phenotypic screening of the ToxCast chemical library to classify toxic and therapeutic mechanisms. Nature Biotechnology. 32: 583-91. PMID 24837663 DOI: 10.1038/Nbt.2914  0.435
2014 Wilson A, Reif DM, Reich BJ. Hierarchical dose-response modeling for high-throughput toxicity screening of environmental chemicals. Biometrics. 70: 237-46. PMID 24397816 DOI: 10.1111/Biom.12114  0.432
2014 Truong L, Reif DM, Mary LS, Geier MC, Truong HD, Tanguay RL. Multidimensional in vivo hazard assessment using zebrafish Toxicological Sciences. 137: 212-233. PMID 24136191 DOI: 10.1093/Toxsci/Kft235  0.667
2014 Bushnell P, Tatum-Gibbs R, McKee J, Evansky P, Higuchi M, MLin M, Oshiro W, Judson R, Hester S, Reif D, Morozova T, Mackay T, Boyes W. ToxiFly: Can fruit flies be used to identify toxicity pathways for airborne chemicals? Neurotoxicology and Teratology. 43: 89. DOI: 10.1016/J.Ntt.2014.04.045  0.345
2013 Williams-DeVane CR, Reif DM, Hubal EC, Bushel PR, Hudgens EE, Gallagher JE, Edwards SW. Decision tree-based method for integrating gene expression, demographic, and clinical data to determine disease endotypes. Bmc Systems Biology. 7: 119. PMID 24188919 DOI: 10.1186/1752-0509-7-119  0.341
2013 Wambaugh JF, Setzer RW, Pitruzzello AM, Liu J, Reif DM, Kleinstreuer NC, Wang NC, Sipes N, Martin M, Das K, DeWitt JC, Strynar M, Judson R, Houck KA, Lau C. Dosimetric anchoring of in vivo and in vitro studies for perfluorooctanoate and perfluorooctanesulfonate. Toxicological Sciences : An Official Journal of the Society of Toxicology. 136: 308-27. PMID 24046276 DOI: 10.1093/Toxsci/Kft204  0.321
2013 Ducharme NA, Peterson LE, Benfenati E, Reif D, McCollum CW, Gustafsson JÅ, Bondesson M. Meta-analysis of toxicity and teratogenicity of 133 chemicals from zebrafish developmental toxicity studies. Reproductive Toxicology (Elmsford, N.Y.). 41: 98-108. PMID 23796950 DOI: 10.1016/J.Reprotox.2013.06.070  0.391
2013 Wambaugh JF, Setzer RW, Reif DM, Gangwal S, Mitchell-Blackwood J, Arnot JA, Joliet O, Frame A, Rabinowitz J, Knudsen TB, Judson RS, Egeghy P, Vallero D, Cohen Hubal EA. High-throughput models for exposure-based chemical prioritization in the ExpoCast project. Environmental Science & Technology. 47: 8479-88. PMID 23758710 DOI: 10.1021/Es400482G  0.423
2013 Rotroff DM, Dix DJ, Houck KA, Kavlock RJ, Knudsen TB, Martin MT, Reif DM, Richard AM, Sipes NS, Abassi YA, Jin C, Stampfl M, Judson RS. Real-time growth kinetics measuring hormone mimicry for ToxCast chemicals in T-47D human ductal carcinoma cells. Chemical Research in Toxicology. 26: 1097-107. PMID 23682706 DOI: 10.1021/Tx400117Y  0.355
2013 Sipes NS, Martin MT, Kothiya P, Reif DM, Judson RS, Richard AM, Houck KA, Dix DJ, Kavlock RJ, Knudsen TB. Profiling 976 ToxCast chemicals across 331 enzymatic and receptor signaling assays. Chemical Research in Toxicology. 26: 878-95. PMID 23611293 DOI: 10.1021/Tx400021F  0.427
2013 Kleinstreuer N, Dix D, Rountree M, Baker N, Sipes N, Reif D, Spencer R, Knudsen T. A computational model predicting disruption of blood vessel development. Plos Computational Biology. 9: e1002996. PMID 23592958 DOI: 10.1371/Journal.Pcbi.1002996  0.322
2013 Judson R, Kavlock R, Martin M, Reif D, Houck K, Knudsen T, Richard A, Tice RR, Whelan M, Xia M, Huang R, Austin C, Daston G, Hartung T, Fowle JR, et al. Perspectives on validation of high-throughput assays supporting 21st century toxicity testing. Altex. 30: 51-6. PMID 23338806 DOI: 10.14573/Altex.2013.1.051  0.368
2013 Reif DM, Sypa M, Lock EF, Wright FA, Wilson A, Cathey T, Judson RR, Rusyn I. ToxPi GUI: an interactive visualization tool for transparent integration of data from diverse sources of evidence. Bioinformatics (Oxford, England). 29: 402-3. PMID 23202747 DOI: 10.1093/Bioinformatics/Bts686  0.334
2013 Rotroff DM, Dix DJ, Houck KA, Knudsen TB, Martin MT, McLaurin KW, Reif DM, Crofton KM, Singh AV, Xia M, Huang R, Judson RS. Using in vitro high throughput screening assays to identify potential endocrine-disrupting chemicals. Environmental Health Perspectives. 121: 7-14. PMID 23052129 DOI: 10.1289/Ehp.1205065  0.384
2013 Kleinstreuer NC, Dix DJ, Houck KA, Kavlock RJ, Knudsen TB, Martin MT, Paul KB, Reif DM, Crofton KM, Hamilton K, Hunter R, Shah I, Judson RS. In vitro perturbations of targets in cancer hallmark processes predict rodent chemical carcinogenesis. Toxicological Sciences : An Official Journal of the Society of Toxicology. 131: 40-55. PMID 23024176 DOI: 10.1093/Toxsci/Kfs285  0.375
2012 Gory JJ, Sweeney HC, Reif DM, Motsinger-Reif AA. A comparison of internal model validation methods for multifactor dimensionality reduction in the case of genetic heterogeneity. Bmc Research Notes. 5: 623. PMID 23126544 DOI: 10.1186/1756-0500-5-623  0.309
2012 Gangwal S, Reif DM, Mosher S, Egeghy PP, Wambaugh JF, Judson RS, Hubal EA. Incorporating exposure information into the toxicological prioritization index decision support framework. The Science of the Total Environment. 435: 316-25. PMID 22863807 DOI: 10.1016/J.Scitotenv.2012.06.086  0.389
2012 Kavlock R, Chandler K, Houck K, Hunter S, Judson R, Kleinstreuer N, Knudsen T, Martin M, Padilla S, Reif D, Richard A, Rotroff D, Sipes N, Dix D. Update on EPA's ToxCast program: providing high throughput decision support tools for chemical risk management. Chemical Research in Toxicology. 25: 1287-302. PMID 22519603 DOI: 10.1021/Tx3000939  0.396
2012 Judson RS, Martin MT, Egeghy P, Gangwal S, Reif DM, Kothiya P, Wolf M, Cathey T, Transue T, Smith D, Vail J, Frame A, Mosher S, Cohen Hubal EA, Richard AM. Aggregating data for computational toxicology applications: The U.S. Environmental Protection Agency (EPA) Aggregated Computational Toxicology Resource (ACToR) System. International Journal of Molecular Sciences. 13: 1805-31. PMID 22408426 DOI: 10.3390/Ijms13021805  0.436
2012 Padilla S, Corum D, Padnos B, Hunter DL, Beam A, Houck KA, Sipes N, Kleinstreuer N, Knudsen T, Dix DJ, Reif DM. Zebrafish developmental screening of the ToxCast™ Phase I chemical library. Reproductive Toxicology (Elmsford, N.Y.). 33: 174-87. PMID 22182468 DOI: 10.1016/J.Reprotox.2011.10.018  0.406
2011 Sipes NS, Martin MT, Reif DM, Kleinstreuer NC, Judson RS, Singh AV, Chandler KJ, Dix DJ, Kavlock RJ, Knudsen TB. Predictive models of prenatal developmental toxicity from ToxCast high-throughput screening data. Toxicological Sciences : An Official Journal of the Society of Toxicology. 124: 109-27. PMID 21873373 DOI: 10.1093/Toxsci/Kfr220  0.395
2011 Kleinstreuer NC, Judson RS, Reif DM, Sipes NS, Singh AV, Chandler KJ, Dewoskin R, Dix DJ, Kavlock RJ, Knudsen TB. Environmental impact on vascular development predicted by high-throughput screening. Environmental Health Perspectives. 119: 1596-603. PMID 21788198 DOI: 10.1289/Ehp.1103412  0.444
2011 Chandler KJ, Barrier M, Jeffay S, Nichols HP, Kleinstreuer NC, Singh AV, Reif DM, Sipes NS, Judson RS, Dix DJ, Kavlock R, Hunter ES, Knudsen TB. Evaluation of 309 environmental chemicals using a mouse embryonic stem cell adherent cell differentiation and cytotoxicity assay. Plos One. 6: e18540. PMID 21666745 DOI: 10.1371/Journal.Pone.0018540  0.368
2011 Martin MT, Knudsen TB, Reif DM, Houck KA, Judson RS, Kavlock RJ, Dix DJ. Predictive model of rat reproductive toxicity from ToxCast high throughput screening. Biology of Reproduction. 85: 327-39. PMID 21565999 DOI: 10.1095/Biolreprod.111.090977  0.417
2011 Knudsen TB, Houck KA, Sipes NS, Singh AV, Judson RS, Martin MT, Weissman A, Kleinstreuer NC, Mortensen HM, Reif DM, Rabinowitz JR, Setzer RW, Richard AM, Dix DJ, Kavlock RJ. Activity profiles of 309 ToxCastâ„¢ chemicals evaluated across 292 biochemical targets. Toxicology. 282: 1-15. PMID 21251949 DOI: 10.1016/J.Tox.2010.12.010  0.429
2011 Rotroff DM, Dix D, Knudsen T, Martin M, Singh AV, McLaurin K, Reif D, Judson R. Using ToxCast Data to Characterize Assay Utility for More Efficient Endocrine Disruptor Screening. Biology of Reproduction. 85: 797-797. DOI: 10.1093/Biolreprod/85.S1.797  0.332
2010 Reif DM, Martin MT, Tan SW, Houck KA, Judson RS, Richard AM, Knudsen TB, Dix DJ, Kavlock RJ. Endocrine profiling and prioritization of environmental chemicals using ToxCast data. Environmental Health Perspectives. 118: 1714-20. PMID 20826373 DOI: 10.1289/Ehp.1002180  0.382
2010 Rotroff DM, Wetmore BA, Dix DJ, Ferguson SS, Clewell HJ, Houck KA, Lecluyse EL, Andersen ME, Judson RS, Smith CM, Sochaski MA, Kavlock RJ, Boellmann F, Martin MT, Reif DM, et al. Incorporating human dosimetry and exposure into high-throughput in vitro toxicity screening. Toxicological Sciences : An Official Journal of the Society of Toxicology. 117: 348-58. PMID 20639261 DOI: 10.1093/Toxsci/Kfq220  0.399
2010 Judson RS, Martin MT, Reif DM, Houck KA, Knudsen TB, Rotroff DM, Xia M, Sakamuru S, Huang R, Shinn P, Austin CP, Kavlock RJ, Dix DJ. Analysis of eight oil spill dispersants using rapid, in vitro tests for endocrine and other biological activity. Environmental Science & Technology. 44: 5979-85. PMID 20602530 DOI: 10.1021/Es102150Z  0.325
2010 Rotroff DM, Beam AL, Dix DJ, Farmer A, Freeman KM, Houck KA, Judson RS, LeCluyse EL, Martin MT, Reif DM, Ferguson SS. Xenobiotic-metabolizing enzyme and transporter gene expression in primary cultures of human hepatocytes modulated by ToxCast chemicals. Journal of Toxicology and Environmental Health. Part B, Critical Reviews. 13: 329-46. PMID 20574906 DOI: 10.1080/10937404.2010.483949  0.324
2010 Judson RS, Houck KA, Kavlock RJ, Knudsen TB, Martin MT, Mortensen HM, Reif DM, Rotroff DM, Shah I, Richard AM, Dix DJ. In vitro screening of environmental chemicals for targeted testing prioritization: the ToxCast project. Environmental Health Perspectives. 118: 485-92. PMID 20368123 DOI: 10.1289/Ehp.0901392  0.406
2010 Martin MT, Dix DJ, Judson RS, Kavlock RJ, Reif DM, Richard AM, Rotroff DM, Romanov S, Medvedev A, Poltoratskaya N, Gambarian M, Moeser M, Makarov SS, Houck KA. Impact of environmental chemicals on key transcription regulators and correlation to toxicity end points within EPA's ToxCast program. Chemical Research in Toxicology. 23: 578-90. PMID 20143881 DOI: 10.1021/Tx900325G  0.407
2009 Martin MT, Judson RS, Reif DM, Kavlock RJ, Dix DJ. Profiling chemicals based on chronic toxicity results from the U.S. EPA ToxRef Database. Environmental Health Perspectives. 117: 392-9. PMID 19337514 DOI: 10.1289/Ehp.0800074  0.348
2009 Heidenfelder BL, Reif DM, Harkema JR, Cohen Hubal EA, Hudgens EE, Bramble LA, Wagner JG, Morishita M, Keeler GJ, Edwards SW, Gallagher JE. Comparative microarray analysis and pulmonary changes in Brown Norway rats exposed to ovalbumin and concentrated air particulates. Toxicological Sciences : An Official Journal of the Society of Toxicology. 108: 207-21. PMID 19176365 DOI: 10.1093/Toxsci/Kfp005  0.319
2009 Reif DM, Motsinger-Reif AA, McKinney BA, Rock MT, Crowe JE, Moore JH. Integrated analysis of genetic and proteomic data identifies biomarkers associated with adverse events following smallpox vaccination. Genes and Immunity. 10: 112-9. PMID 18923431 DOI: 10.1038/Gene.2008.80  0.496
2008 Hardison NE, Fanelli TJ, Dudek SM, Reif DM, Ritchie MD, Motsinger-Reif AA. A Balanced Accuracy Fitness Function Leads to Robust Analysis using Grammatical Evolution Neural Networks in the Case of Class Imbalance. Genetic and Evolutionary Computation Conference : [Proceedings] / Sponsored by Acm Sigevo. Genetic and Evolutionary Computation Conference. 2008: 353-354. PMID 21197143 DOI: 10.1145/1389095.1389159  0.41
2008 Motsinger-Reif AA, Reif DM, Fanelli TJ, Ritchie MD. A comparison of analytical methods for genetic association studies. Genetic Epidemiology. 32: 767-78. PMID 18561203 DOI: 10.1002/Gepi.20345  0.519
2008 Reif DM, McKinney BA, Motsinger AA, Chanock SJ, Edwards KM, Rock MT, Moore JH, Crowe JE. Genetic basis for adverse events after smallpox vaccination. The Journal of Infectious Diseases. 198: 16-22. PMID 18454680 DOI: 10.1086/588670  0.444
2007 Motsinger AA, Reif DM, Fanelli TJ, Davis AC, Ritchie MD. Linkage Disequilibrium in Genetic Association Studies Improves the Performance of Grammatical Evolution Neural Networks. Proceedings of the ... Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology. Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology. 2007: 1-8. PMID 21572972  0.455
2007 Reif DM, Israel MA, Moore JH. Exploratory Visual Analysis of statistical results from microarray experiments comparing high and low grade glioma. Cancer Informatics. 5: 19-24. PMID 19390666 DOI: 10.4137/Cin.S0  0.494
2007 Motsinger AA, Ritchie MD, Reif DM. Novel methods for detecting epistasis in pharmacogenomics studies. Pharmacogenomics. 8: 1229-41. PMID 17924838 DOI: 10.2217/14622416.8.9.1229  0.527
2007 McKinney BA, Reif DM, White BC, Crowe JE, Moore JH. Evaporative cooling feature selection for genotypic data involving interactions. Bioinformatics (Oxford, England). 23: 2113-20. PMID 17586549 DOI: 10.1093/Bioinformatics/Btm317  0.471
2006 Motsinger AA, Reif DM, Dudek SM, Ritchie MD. Understanding the Evolutionary Process of Grammatical Evolution Neural Networks for Feature Selection in Genetic Epidemiology. Proceedings of the ... Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology. Ieee Symposium On Computational Intelligence in Bioinformatics and Computational Biology. 2006: 1-8. PMID 20634919 DOI: 10.1109/CIBCB.2006.330945  0.441
2006 McKinney BA, Reif DM, Rock MT, Edwards KM, Kingsmore SF, Moore JH, Crowe JE. Cytokine expression patterns associated with systemic adverse events following smallpox immunization. The Journal of Infectious Diseases. 194: 444-53. PMID 16845627 DOI: 10.1086/505503  0.437
2006 McKinney BA, Reif DM, Ritchie MD, Moore JH. Machine learning for detecting gene-gene interactions: a review. Applied Bioinformatics. 5: 77-88. PMID 16722772 DOI: 10.2165/00822942-200605020-00002  0.59
2006 Reif DM, Moore JH. Visual analysis of statistical results from microarray studies of human breast cancer. Oncology Reports. 15: 1043-7. PMID 16525698  0.433
2005 Wilke RA, Reif DM, Moore JH. Combinatorial pharmacogenetics. Nature Reviews. Drug Discovery. 4: 911-8. PMID 16264434 DOI: 10.1038/nrd1874  0.407
2005 Reif DM, Dudek SM, Shaffer CM, Wang J, Moore JH. Exploratory visual analysis of pharmacogenomic results. Pacific Symposium On Biocomputing. Pacific Symposium On Biocomputing. 296-307. PMID 15759635  0.421
2004 Reif DM, White BC, Moore JH. Integrated analysis of genetic, genomic and proteomic data. Expert Review of Proteomics. 1: 67-75. PMID 15966800 DOI: 10.1586/14789450.1.1.67  0.516
Show low-probability matches.