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Quan Cai - Publications

Affiliations: 
Dana Farber Cancer Institute, Boston, MA, United States 
Area:
Drug Discovery
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26 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Xu MM, Xie PP, He JX, Zhang YZ, Zheng C, Cai Q. Enantioselective Cross-[4 + 2]-Cycloaddition/Decarboxylation of 2-Pyrones by Cooperative Catalysis of the Pd(0)/NHC Complex and Chiral Phosphoric Acid. Journal of the American Chemical Society. 146: 6936-6946. PMID 38414423 DOI: 10.1021/jacs.3c14409  0.323
2023 Zhang ZM, Zhang J, Cai Q. Enantioselective and collective total synthesis of pentacyclic 19--clerodanes. Chemical Science. 14: 12598-12605. PMID 38020367 DOI: 10.1039/d3sc04335e  0.362
2023 Si XG, Feng SX, Wang ZY, Chen X, Xu MM, Zhang YZ, He JX, Yang L, Cai Q. Enantioselective Synthesis of cis-Decalins by Merging the Birch Reduction and Inverse-Electron-Demand Diels-Alder Reaction. Angewandte Chemie (International Ed. in English). e202303876. PMID 37286494 DOI: 10.1002/anie.202303876  0.323
2022 Zhang YZ, Xu MM, Si XG, Hou JL, Cai Q. Enantioselective Synthesis of Inherently Chiral Calix[4]arenes via Palladium-Catalyzed Asymmetric Intramolecular C-H Arylations. Journal of the American Chemical Society. 144: 22858-22864. PMID 36480794 DOI: 10.1021/jacs.2c10606  0.35
2022 Silva MC, Nandi G, Donovan KA, Cai Q, Berry BC, Nowak RP, Fischer ES, Gray NS, Ferguson FM, Haggarty SJ. Discovery and Optimization of Tau Targeted Protein Degraders Enabled by Patient Induced Pluripotent Stem Cells-Derived Neuronal Models of Tauopathy. Frontiers in Cellular Neuroscience. 16: 801179. PMID 35317195 DOI: 10.3389/fncel.2022.801179  0.655
2021 Xu MM, You XY, Zhang YZ, Lu Y, Tan K, Yang L, Cai Q. Enantioselective Synthesis of Axially Chiral Biaryls by Diels-Alder/Retro-Diels-Alder Reaction of 2-Pyrones with Alkynes. Journal of the American Chemical Society. PMID 34106720 DOI: 10.1021/jacs.1c04759  0.348
2021 Remenyi J, Naik RJ, Wang J, Razsolkov M, Verano A, Cai Q, Tan L, Toth R, Raggett S, Baillie C, Traynor R, Hastie CJ, Gray NS, Arthur JSC. Generation of a chemical genetic model for JAK3. Scientific Reports. 11: 10093. PMID 33980892 DOI: 10.1038/s41598-021-89356-4  0.335
2019 Faust TB, Yoon H, Nowak RP, Donovan KA, Li Z, Cai Q, Eleuteri NA, Zhang T, Gray NS, Fischer ES. Structural complementarity facilitates E7820-mediated degradation of RBM39 by DCAF15. Nature Chemical Biology. PMID 31686031 DOI: 10.1038/s41589-019-0378-3  0.374
2019 Silva MC, Ferguson FM, Cai Q, Donovan KA, Nandi G, Patnaik D, Zhang T, Huang HT, Lucente DE, Dickerson BC, Mitchison TJ, Fischer ES, Gray NS, Haggarty SJ. Targeted degradation of aberrant tau in frontotemporal dementia patient-derived neuronal cell models. Elife. 8. PMID 30907729 DOI: 10.7554/Elife.45457  0.649
2017 Nicolaou KC, Chen P, Zhu S, Cai Q, Erande RD, Li R, Sun H, Pulukuri KK, Rigol S, Aujay M, Sandoval J, Gavrilyuk J. Streamlined Total Synthesis of Trioxacarcins and Its Application to the Design, Synthesis, and Biological Evaluation of Analogues Thereof. Discovery of Simpler Designed and Potent Trioxacarcin Analogues. Journal of the American Chemical Society. PMID 29052423 DOI: 10.1021/Jacs.7B08820  0.649
2016 Nicolaou KC, Cai Q, Sun H, Qin B, Zhu S. Total Synthesis of Trioxacarcins DC-45-A1, A, D, C, and C7″-epi-C and Full Structural Assignment of Trioxacarcin C. Journal of the American Chemical Society. PMID 26910506 DOI: 10.1021/Jacs.5B12687  0.461
2015 Nicolaou KC, Cai Q, Qin B, Petersen MT, Mikkelsen RJ, Heretsch P. Total synthesis of trioxacarcin DC-45-A2. Angewandte Chemie (International Ed. in English). 54: 3074-8. PMID 25583408 DOI: 10.1002/Anie.201410369  0.661
2014 Cai Q, Yin Q, You SL. Chiral-amine-catalyzed asymmetric bromocyclization of tryptamine derivatives Asian Journal of Organic Chemistry. 3: 408-411. DOI: 10.1002/Ajoc.201300146  0.688
2013 Zhang JW, Cai Q, Gu Q, Shi XX, You SL. Enantioselective synthesis of benzofurans and benzoxazines via an olefin cross-metathesis-intramolecular oxo-Michael reaction. Chemical Communications (Cambridge, England). 49: 7750-2. PMID 23884172 DOI: 10.1039/C3Cc43937B  0.616
2013 Nicolaou KC, Yu R, Shi L, Cai Q, Lu M, Heretsch P. General synthetic approach to functionalized dihydrooxepines. Organic Letters. 15: 1994-7. PMID 23550898 DOI: 10.1021/Ol4006689  0.65
2013 Cai Q, Liang XW, Wang SG, You SL. An olefin isomerization/asymmetric Pictet-Spengler cascade via sequential catalysis of ruthenium alkylidene and chiral phosphoric acid. Organic & Biomolecular Chemistry. 11: 1602-5. PMID 23364474 DOI: 10.1039/C3Ob00072A  0.602
2012 Cai Q, Liang XW, Wang SG, Zhang JW, Zhang X, You SL. Ring-closing metathesis/isomerization/Pictet-Spengler cascade via ruthenium/chiral phosphoric acid sequential catalysis. Organic Letters. 14: 5022-5. PMID 22988945 DOI: 10.1021/Ol302215U  0.609
2012 Cai Q, Liu C, Liang XW, You SL. Enantioselective construction of pyrroloindolines via chiral phosphoric acid catalyzed cascade Michael addition-cyclization of tryptamines. Organic Letters. 14: 4588-90. PMID 22928846 DOI: 10.1021/Ol302043S  0.607
2012 Cai Q, You SL. Organocatalyzed enantioselective formal [4 + 2] cycloaddition of 2,3-disubstituted indole and methyl vinyl ketone. Organic Letters. 14: 3040-3. PMID 22626008 DOI: 10.1021/Ol301114Z  0.587
2011 Cai Q, Zheng C, Zhang JW, You SL. Enantioselective Michael/Mannich polycyclization cascade of indolyl enones catalyzed by quinine-derived primary amines. Angewandte Chemie (International Ed. in English). 50: 8665-9. PMID 21793147 DOI: 10.1002/Anie.201103937  0.593
2011 Zhang J, Cai Q, Shi X, Zhang W, You S. Enantioselective Synthesisof Tetrahydropyrano[3,4-b]indolesCatalyzed by Chiral N-Triflyl Phosphoramidevia Intramolecular Friedel-Crafts Alkylation Reaction Synlett. 2011: 1239-1242. DOI: 10.1055/S-0030-1260537  0.578
2010 Cai Q, Zheng C, You SL. Enantioselective intramolecular aza-Michael additions of indoles catalyzed by chiral phosphoric acids. Angewandte Chemie (International Ed. in English). 49: 8666-9. PMID 20931585 DOI: 10.1002/Anie.201003919  0.599
2010 You S, Cai Q, Zheng C. Intramolecular Aza-Michael Addition of Indoles Synfacts. 2010: 1428-1428. DOI: 10.1055/S-0030-1258922  0.448
2009 Cai Q, Zhao ZA, You SL. Asymmetric construction of polycyclic indoles through olefin cross-metathesis/intramolecular Friedel-Crafts alkylation under sequential catalysis. Angewandte Chemie (International Ed. in English). 48: 7428-31. PMID 19739165 DOI: 10.1002/Anie.200903462  0.567
2009 You SL, Cai Q, Zeng M. Chiral Brønsted acid catalyzed Friedel-Crafts alkylation reactions. Chemical Society Reviews. 38: 2190-201. PMID 19623343 DOI: 10.1039/B817310A  0.564
2009 You S, Cai Q, Zhao Z. Asymmetric Construction of Polycyclic Indoles via Sequential Catalysis Synfacts. 2009: 1375-1375. DOI: 10.1055/S-0029-1218243  0.365
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