| Year |
Citation |
Score |
| 2023 |
Weerawarna PM, Schiefer IT, Soares P, Fox S, Morimoto RI, Melani RD, Kelleher NL, Luan CH, Silverman RB. Target Identification of a Class of Pyrazolone Protein Aggregation Inhibitor Therapeutics for Amyotrophic Lateral Sclerosis. Acs Central Science. 10: 87-103. PMID 38292603 DOI: 10.1021/acscentsci.3c00213 |
0.489 |
|
| 2020 |
Tackie-Yarboi E, Wisner A, Horton A, Chau TQT, Reigle J, Funk AJ, Mccullumsmith RE, Hall FS, Williams FE, Schiefer IT. Combining Neurobehavioral Analysis and In Vivo Photoaffinity Labeling to Understand Protein Targets of Methamphetamine in Casper Zebrafish. Acs Chemical Neuroscience. PMID 32786314 DOI: 10.1021/Acschemneuro.0C00416 |
0.359 |
|
| 2019 |
Horton A, Schiefer IT. Pharmacokinetics and pharmacodynamics of nitric oxide mimetic agents. Nitric Oxide : Biology and Chemistry. PMID 30641123 DOI: 10.1016/J.Niox.2019.01.001 |
0.343 |
|
| 2018 |
Horton A, Nash K, Tackie-Yarboi E, Kostrevski A, Novak A, Raghavan A, Tulsulkar J, Alhadidi Q, Wamer N, Langenderfer B, Royster K, Ducharme M, Hagood K, Post M, Shah ZA, ... Schiefer IT, et al. Furoxans (oxadiazole-4N-oxides) with Attenuated Reactivity are Neuroprotective, Cross the Blood Brain Barrier, and Improve Passive Avoidance Memory. Journal of Medicinal Chemistry. PMID 29683322 DOI: 10.1021/Acs.Jmedchem.8B00389 |
0.355 |
|
| 2017 |
Nash KM, Schiefer IT, Shah ZA. Development of a reactive oxygen species-sensitive nitric oxide synthase inhibitor for the treatment of ischemic stroke. Free Radical Biology & Medicine. 115: 395-404. PMID 29275014 DOI: 10.1016/J.Freeradbiomed.2017.12.027 |
0.33 |
|
| 2015 |
Fà M, Zhang H, Staniszewski A, Saeed F, Shen LW, Schiefer IT, Siklos MI, Tapadar S, Litosh VA, Libien J, Petukhov PA, Teich AF, Thatcher GR, Arancio O. Novel Selective Calpain 1 Inhibitors as Potential Therapeutics in Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 26484927 DOI: 10.3233/Jad-150618 |
0.584 |
|
| 2014 |
Trippier PC, Zhao KT, Fox SG, Schiefer IT, Benmohamed R, Moran J, Kirsch DR, Morimoto RI, Silverman RB. Proteasome activation is a mechanism for pyrazolone small molecules displaying therapeutic potential in amyotrophic lateral sclerosis. Acs Chemical Neuroscience. 5: 823-9. PMID 25001311 DOI: 10.1021/Cn500147V |
0.649 |
|
| 2013 |
Schiefer IT, Tapadar S, Litosh V, Siklos M, Scism R, Wijewickrama GT, Chandrasena EP, Sinha V, Tavassoli E, Brunsteiner M, Fa' M, Arancio O, Petukhov P, Thatcher GR. Design, synthesis, and optimization of novel epoxide incorporating peptidomimetics as selective calpain inhibitors. Journal of Medicinal Chemistry. 56: 6054-68. PMID 23834438 DOI: 10.1021/Jm4006719 |
0.58 |
|
| 2013 |
Siklos MI, Gandhi RP, Xiong R, Schiefer IT, Litosh V, VandeVrede L, Thatcher GR. Discovery of neuroprotective soluble guanylate cyclase modulators (GCMs) aciting via NO/GC/cGMP/CREB pathway Bmc Pharmacology and Toxicology. 14. DOI: 10.1186/2050-6511-14-S1-P65 |
0.587 |
|
| 2012 |
Schiefer IT, VandeVrede L, Fa' M, Arancio O, Thatcher GR. Furoxans (1,2,5-oxadiazole-N-oxides) as novel NO mimetic neuroprotective and procognitive agents. Journal of Medicinal Chemistry. 55: 3076-87. PMID 22429006 DOI: 10.1021/Jm201504S |
0.586 |
|
| 2011 |
Abdul-Hay S, Schiefer IT, Chandrasena RE, Li M, Abdelhamid R, Wang YT, Tavassoli E, Michalsen B, Asghodom RT, Luo J, Thatcher GR. NO-SSRIs: Nitric Oxide Chimera Drugs Incorporating a Selective Serotonin Reuptake Inhibitor. Acs Medicinal Chemistry Letters. 2: 656-661. PMID 21927645 DOI: 10.1021/Ml2000033 |
0.665 |
|
| 2011 |
Abdelhamid R, Luo J, Vandevrede L, Kundu I, Michalsen B, Litosh VA, Schiefer IT, Gherezghiher T, Yao P, Qin Z, Thatcher GR. Benzothiophene Selective Estrogen Receptor Modulators Provide Neuroprotection by a novel GPR30-dependent Mechanism. Acs Chemical Neuroscience. 2: 256-268. PMID 21731800 DOI: 10.1021/Cn100106A |
0.548 |
|
| 2011 |
Schiefer IT, Abdul-Hay S, Wang H, Vanni M, Qin Z, Thatcher GR. Inhibition of amyloidogenesis by nonsteroidal anti-inflammatory drugs and their hybrid nitrates. Journal of Medicinal Chemistry. 54: 2293-306. PMID 21405086 DOI: 10.1021/Jm101450P |
0.661 |
|
| 2010 |
Sinha V, Wijewickrama GT, Chandrasena RE, Xu H, Edirisinghe PD, Schiefer IT, Thatcher GR. Proteomic and mass spectroscopic quantitation of protein S-nitrosation differentiates NO-donors. Acs Chemical Biology. 5: 667-80. PMID 20524644 DOI: 10.1021/Cb100054M |
0.527 |
|
| 2010 |
Anand S, Schiefer IT, Thatcher GRJ. Nitric oxide donor and mimetic molecules in cancer chemotherapy and chemoprevention Forum On Immunopathological Diseases and Therapeutics. 1: 251-279. DOI: 10.1615/Forumimmundisther.V1.I4.20 |
0.476 |
|
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