Year |
Citation |
Score |
2018 |
Pedersen MJ, Skovby T, Mealy MJ, Dam-Johansen K, Kiil S. Redesign of a Grignard-Based Active Pharmaceutical Ingredient (API) Batch Synthesis to a Flow Process for the Preparation of Melitracen HCl Organic Process Research & Development. 22: 228-235. DOI: 10.1021/Acs.Oprd.7B00368 |
0.319 |
|
2018 |
Pedersen MJ, Born S, Neuenschwander U, Skovby T, Mealy MJ, Kiil S, Dam-Johansen K, Jensen KF. Optimization of Grignard Addition to Esters: Kinetic and Mechanistic Study of Model Phthalide Using Flow Chemistry Industrial & Engineering Chemistry Research. 57: 4859-4866. DOI: 10.1021/Acs.Iecr.8B00564 |
0.303 |
|
2014 |
Luderer MR, Mealy MJ, Bailey WF. Asymmetric intramolecular carbolithiation of achiral substrates: synthesis of enantioenriched (R)-(+)-cuparene and (R)-(+)-herbertene. The Journal of Organic Chemistry. 79: 10722-6. PMID 25303318 DOI: 10.1021/Jo502139M |
0.611 |
|
2008 |
Dahl AC, Mealy MJ, Nielsen MA, Lyngsø LO, Suteu C. Route Scouting and Process Development of Lu AA26778 Organic Process Research & Development. 12: 429-441. DOI: 10.1021/Op7002584 |
0.394 |
|
2005 |
Bailey WF, Luderer MR, Mealy MJ, Punzalan ER, Denmark SE, Macneil SL. Generation and cyclization of 5-hexenyllithium: 2-cyclopentylacetophenone: (ethanone, 2-cyclopentyl-1-phenyl-) Organic Syntheses. 81: 121-133. DOI: 10.15227/Orgsyn.081.0121 |
0.553 |
|
2005 |
Bailey WF, Luderer MR, Mealy MJ, Punzalan ER. Generation and Cyclization of 5‐Hexenyllithium: 2‐Cyclopentylacetophenone Organic Syntheses. 121-133. DOI: 10.1002/0471264229.Os081.13 |
0.572 |
|
2004 |
Mealy MJ, Luderer MR, Bailey WF, Sommer MB. Effect of ligand structure on the asymmetric cyclization of achiral olefinic organolithiums. The Journal of Organic Chemistry. 69: 6042-9. PMID 15373489 DOI: 10.1021/Jo049477+ |
0.623 |
|
2003 |
Bailey WF, Luderer MR, Mealy MJ. Preparation of differentially 1,3-disubstituted indolines by intramolecular carbolithiation Tetrahedron Letters. 44: 5303-5305. DOI: 10.1016/S0040-4039(03)01204-8 |
0.627 |
|
2002 |
Bailey WF, Mealy MJ, Wiberg KB. Comparative study of anionic and radical cyclization for the preparation of 1,3-dimethylindans: highly stereoselective preparation of cis-1,3-disubstituted indans via intramolecular carbolithiation. Organic Letters. 4: 791-4. PMID 11869129 DOI: 10.1021/Ol017291G |
0.579 |
|
2002 |
Mealy MJ, Bailey WF. Synthesis of heterocycles by cyclization of unsaturated organolithiums: a review Journal of Organometallic Chemistry. 646: 59-67. DOI: 10.1016/S0022-328X(01)01244-X |
0.52 |
|
2000 |
and WFB, Mealy MJ. Asymmetric Cyclization of Achiral Olefinic Organolithiums Controlled by a Stereogenic Lithium: Intramolecular Carbolithiation in the Presence of (−)-Sparteine Journal of the American Chemical Society. 122: 6787-6788. DOI: 10.1021/Ja000471L |
0.354 |
|
Low-probability matches (unlikely to be authored by this person) |
2016 |
Pedersen MJ, Skovby T, Mealy MJ, Dam-Johansen K, Kiil S. A Solvent-Free Base Liberation of a Tertiary Aminoalkyl Halide by Flow Chemistry Organic Process Research & Development. 20: 2043-2049. DOI: 10.1021/Acs.Oprd.6B00223 |
0.292 |
|
2016 |
Gouveia FF, Rahbek JP, Mortensen AR, Pedersen MT, Felizardo PM, Bro R, Mealy MJ. Using PAT to accelerate the transition to continuous API manufacturing. Analytical and Bioanalytical Chemistry. PMID 27515798 DOI: 10.1007/S00216-016-9834-Z |
0.269 |
|
2013 |
Pedersen MJ, Holm TL, Rahbek JP, Skovby T, Mealy MJ, Dam-Johansen K, Kiil S. Full-scale continuous mini-reactor setup for heterogeneous grignard alkylation of a pharmaceutical intermediate Organic Process Research and Development. 17: 1142-1148. DOI: 10.1021/Op400069E |
0.217 |
|
2017 |
Capellades G, Kiil S, Dam-Johansen K, Mealy MJ, Christensen TV, Myerson AS. Effect of Air Injection on Nucleation Rates: An Approach from Induction Time Statistics Crystal Growth & Design. 17: 3287-3294. DOI: 10.1021/Acs.Cgd.7B00267 |
0.201 |
|
2018 |
Capellades G, Joshi PU, Dam-Johansen K, Mealy MJ, Christensen TV, Kiil S. Characterization of a Multistage Continuous MSMPR Crystallization Process Assisted by Image Analysis of Elongated Crystals Crystal Growth & Design. 18: 6455-6469. DOI: 10.1021/Acs.Cgd.8B00446 |
0.197 |
|
2019 |
Capellades G, Duso A, Dam-Johansen K, Mealy MJ, Christensen TV, Kiil S. Continuous Crystallization with Gas Entrainment: Evaluating the Effect of a Moving Gas Phase in an MSMPR Crystallizer Organic Process Research & Development. 23: 252-262. DOI: 10.1021/Acs.Oprd.8B00376 |
0.194 |
|
Hide low-probability matches. |