| Year |
Citation |
Score |
| 2023 |
Lee SJ, Kim HY, Lee MJ, Kim SB, Kwon YT, Ji CH. Characterization and chemical modulation of p62/SQSTM1/Sequestosome-1 as an autophagic N-recognin. Methods in Enzymology. 686: 235-265. PMID 37532402 DOI: 10.1016/bs.mie.2023.02.005 |
0.357 |
|
| 2023 |
Kwon SC, Lee J, Kwon YT, Heo AJ. Monitoring the interactions between N-degrons and N-recognins of the Arg/N-degron pathway. Methods in Enzymology. 686: 165-203. PMID 37532399 DOI: 10.1016/bs.mie.2023.05.009 |
0.346 |
|
| 2023 |
Ji CH, Lee MJ, Kim SB, Kwon YT. Analyzing the Interaction of Arginylated Proteins and Nt-Arg-Mimicking Chemical Compounds to N-Recognins. Methods in Molecular Biology (Clifton, N.J.). 2620: 253-262. PMID 37010768 DOI: 10.1007/978-1-0716-2942-0_27 |
0.31 |
|
| 2023 |
Ji CH, Kim SB, Lee MJ, Kwon YT. Monitoring the Activation of Selective Autophagy via N-Terminal Arginylation. Methods in Molecular Biology (Clifton, N.J.). 2620: 243-252. PMID 37010767 DOI: 10.1007/978-1-0716-2942-0_26 |
0.358 |
|
| 2023 |
Heo AJ, Kim SB, Kwon YT, Ji CH. The N-degron pathway: From basic science to therapeutic applications. Biochimica Et Biophysica Acta. Gene Regulatory Mechanisms. 194934. PMID 36990317 DOI: 10.1016/j.bbagrm.2023.194934 |
0.362 |
|
| 2022 |
Shim SM, Choi HR, Kwon SC, Kim HY, Sung KW, Jung EJ, Mun SR, Bae TH, Kim DH, Son YS, Jung CH, Lee J, Lee MJ, Park JW, Kwon YT. The Cys-N-degron pathway modulates pexophagy through the N-terminal oxidation and arginylation of ACAD10. Autophagy. 1-20. PMID 36184612 DOI: 10.1080/15548627.2022.2126617 |
0.352 |
|
| 2022 |
Heo AJ, Ji CH, Kwon YT. The Cys/N-degron pathway in the ubiquitin-proteasome system and autophagy. Trends in Cell Biology. PMID 35945077 DOI: 10.1016/j.tcb.2022.07.005 |
0.369 |
|
| 2022 |
Lee YJ, Kim JK, Jung CH, Kim YJ, Jung EJ, Lee SH, Choi HR, Son YS, Shim SM, Jeon SM, Choe JH, Lee SH, Whang J, Sohn KC, Hur GM, ... ... Kwon YT, et al. Chemical Modulation of SQSTM1/p62-mediated Xenophagy that Targets a Broad Range of Pathogenic Bacteria. Autophagy. PMID 35316156 DOI: 10.1080/15548627.2022.2054240 |
0.321 |
|
| 2021 |
Heo AJ, Kim SB, Ji CH, Han D, Lee SJ, Lee SH, Lee MJ, Lee JS, Ciechanover A, Kim BY, Kwon YT. The N-terminal cysteine is a dual sensor of oxygen and oxidative stress. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34893540 DOI: 10.1073/pnas.2107993118 |
0.302 |
|
| 2021 |
Jang M, Hara S, Kim GH, Kim SM, Son S, Kwon M, Ryoo IJ, Seo H, Kim MJ, Kim ND, Soung NK, Kwon YT, Kim BY, Osada H, Jang JH, et al. Dutomycin Induces Autophagy and Apoptosis by Targeting the Serine Protease Inhibitor SERPINB6. Acs Chemical Biology. PMID 33517652 DOI: 10.1021/acschembio.0c00889 |
0.306 |
|
| 2020 |
Choi WH, Yun Y, Park S, Jeon JH, Lee J, Lee JH, Yang SA, Kim NK, Jung CH, Kwon YT, Han D, Lim SM, Lee MJ. Aggresomal sequestration and STUB1-mediated ubiquitylation during mammalian proteaphagy of inhibited proteasomes. Proceedings of the National Academy of Sciences of the United States of America. PMID 32723828 DOI: 10.1073/Pnas.1920327117 |
0.404 |
|
| 2020 |
Hakim-Eshed V, Boulos A, Cohen-Rosenzweig C, Yu-Taeger L, Ziv T, Kwon YT, Riess O, Phuc Nguyen HH, Ziv NE, Ciechanover A. Site-specific ubiquitination of pathogenic huntingtin attenuates its deleterious effects. Proceedings of the National Academy of Sciences of the United States of America. PMID 32675242 DOI: 10.1073/Pnas.2007667117 |
0.373 |
|
| 2020 |
Han HJ, Park C, Hwang J, N R T, Kim SO, Han J, Woo M, B S, Ryoo IJ, Lee KH, Cha-Molstad H, Kwon YT, Kim BY, Soung NK. CPPF, A Novel Microtubule Targeting Anticancer Agent, Inhibits the Growth of a Wide Variety of Cancers. International Journal of Molecular Sciences. 21. PMID 32645923 DOI: 10.3390/Ijms21134800 |
0.31 |
|
| 2020 |
Kyun ML, Kim SO, Lee HG, Hwang JA, Hwang J, Soung NK, Cha-Molstad H, Lee S, Kwon YT, Kim BY, Lee KH. Wnt3a Stimulation Promotes Primary Ciliogenesis through β-Catenin Phosphorylation-Induced Reorganization of Centriolar Satellites. Cell Reports. 30: 1447-1462.e5. PMID 32023461 DOI: 10.1016/J.Celrep.2020.01.019 |
0.353 |
|
| 2019 |
Ji CH, Kim HY, Heo AJ, Lee MJ, Park DY, Kim DH, Kim BY, Kwon YT. Regulation of reticulophagy by the N-degron pathway. Autophagy. PMID 31744379 DOI: 10.1080/15548627.2019.1695402 |
0.45 |
|
| 2019 |
Kim HM, He L, Lee S, Park C, Kim DH, Han HJ, Han J, Hwang J, Cha-Molstad H, Lee KH, Ko SK, Jang JH, Ryoo IJ, Blenis J, Lee HG, ... ... Kwon YT, et al. Inhibition of osteoclasts differentiation by CDC2-induced NFATc1 phosphorylation. Bone. 115153. PMID 31730830 DOI: 10.1016/J.Bone.2019.115153 |
0.308 |
|
| 2019 |
Ji CH, Kim HY, Heo AJ, Lee SH, Lee MJ, Kim SB, Srinivasrao G, Mun SR, Cha-Molstad H, Ciechanover A, Choi CY, Lee HG, Kim BY, Kwon YT. The N-Degron Pathway Mediates ER-phagy. Molecular Cell. PMID 31375263 DOI: 10.1016/J.Molcel.2019.06.028 |
0.412 |
|
| 2019 |
Kim DH, Ahn JS, Han HJ, Kim HM, Hwang J, Lee KH, Cha-Molstad H, Ryoo IJ, Jang JH, Ko SK, Yang JO, Lee HG, Lee S, Song EJ, Kim JY, ... ... Kwon YT, et al. Cep131 overexpression promotes centrosome amplification and colon cancer progression by regulating Plk4 stability. Cell Death & Disease. 10: 570. PMID 31358734 DOI: 10.1038/S41419-019-1778-8 |
0.331 |
|
| 2019 |
Cohen-Kaplan V, Livneh I, Kwon YT, Ciechanover A. Monitoring stress-induced autophagic engulfment and degradation of the 26S proteasome in mammalian cells. Methods in Enzymology. 619: 337-366. PMID 30910028 DOI: 10.1016/Bs.Mie.2018.12.022 |
0.383 |
|
| 2019 |
Sun H, Mali SM, Singh SK, Meledin R, Brik A, Kwon YT, Kravtsova-Ivantsiv Y, Bercovich B, Ciechanover A. Diverse fate of ubiquitin chain moieties: The proximal is degraded with the target, and the distal protects the proximal from removal and recycles. Proceedings of the National Academy of Sciences of the United States of America. PMID 30867293 DOI: 10.1073/Pnas.1822148116 |
0.353 |
|
| 2019 |
Soung NK, Kim HM, Asami Y, Kim DH, Cho Y, Naik R, Jang Y, Jang K, Han HJ, Ganipisetti SR, Cha-Molstad H, Hwang J, Lee KH, Ko SK, Jang JH, ... ... Kwon YT, et al. Mechanism of the natural product moracin-O derived MO-460 and its targeting protein hnRNPA2B1 on HIF-1α inhibition. Experimental & Molecular Medicine. 51: 10. PMID 30755586 DOI: 10.1038/S12276-018-0200-4 |
0.323 |
|
| 2019 |
Zhang Y, Mun SR, Linares JF, Towers CG, Thorburn A, Diaz-Meco MT, Kwon YT, Kutateladze TG. Mechanistic insight into the regulation of SQSTM1/p62. Autophagy. PMID 30653391 DOI: 10.1080/15548627.2019.1569935 |
0.327 |
|
| 2019 |
Kim DH, Kim HM, Huong PTT, Han HJ, Hwang J, Cha-Molstad H, Lee KH, Ryoo IJ, Kim KE, Huh YH, Ahn JS, Kwon YT, Soung NK, Kim BY. Enhanced anticancer effects of a methylation inhibitor by inhibiting a novel DNMT1 target, CEP 131, in cervical cancer. Journal of Biochemistry and Molecular Biology. 52: 342-347. DOI: 10.5483/Bmbrep.2019.52.5.055 |
0.343 |
|
| 2018 |
Zhang Y, Mun SR, Linares JF, Ahn J, Towers CG, Ji CH, Fitzwalter BE, Holden MR, Mi W, Shi X, Moscat J, Thorburn A, Diaz-Meco MT, Kwon YT, Kutateladze TG. ZZ-dependent regulation of p62/SQSTM1 in autophagy. Nature Communications. 9: 4373. PMID 30349045 DOI: 10.1038/S41467-018-06878-8 |
0.328 |
|
| 2018 |
Kim ST, Lee YJ, Tasaki T, Hwang J, Kang MJ, Yi EC, Kim BY, Kwon YT. The N-recognin UBR4 of the N-end rule pathway is required for neurogenesis and homeostasis of cell surface proteins. Plos One. 13: e0202260. PMID 30157281 DOI: 10.1371/Journal.Pone.0202260 |
0.483 |
|
| 2018 |
Kim ST, Lee YJ, Tasaki T, Mun S, Hwang J, Kang MJ, Ganipisetti S, Yi EC, Kim BY, Kwon YT. The N-recognin UBR4 of the N-end rule pathway is targeted to and required for the biogenesis of the early endosome. Journal of Cell Science. PMID 30111582 DOI: 10.1242/Jcs.217646 |
0.485 |
|
| 2018 |
Lee DH, Kim D, Kim ST, Jeong S, Kim JL, Shim SM, Heo AJ, Song X, Guo ZS, Bartlett DL, Oh SC, Lee J, Saito Y, Kim BY, Kwon YT, et al. PARK7 modulates autophagic proteolysis through binding to the N-terminally arginylated form of the molecular chaperone HSPA5. Autophagy. PMID 29976090 DOI: 10.1080/15548627.2018.1491212 |
0.385 |
|
| 2018 |
Lee YJ, Song X, Lee DH, Dilly AK, Lee YS, Choudry HA, Kwon YT, Bartlett DL. Crosstalk between Apoptosis and Autophagy is Regulated by the Arginylated BiP/Beclin-1/p62 Complex. Molecular Cancer Research : McR. PMID 29669822 DOI: 10.1158/1541-7786.Mcr-17-0685 |
0.395 |
|
| 2018 |
Yoo YD, Mun SR, Ji CH, Sung KW, Kang KY, Heo AJ, Lee SH, An JY, Hwang J, Xie XQ, Ciechanover A, Kim BY, Kwon YT. N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507222 DOI: 10.1073/Pnas.1719110115 |
0.463 |
|
| 2018 |
Shim SM, Choi HR, Sung KW, Lee YJ, Kim ST, Kim D, Mun SR, Hwang J, Cha-Molstad H, Ciechanover A, Kim BY, Kwon YT. The endoplasmic reticulum-residing chaperone BiP is short-lived and metabolized through N-terminal arginylation. Science Signaling. 11. PMID 29295953 DOI: 10.1126/Scisignal.Aan0630 |
0.391 |
|
| 2017 |
Cha-Molstad H, Lee SH, Kim JG, Sung KW, Hwang J, Shim SM, Ganipisetti S, McGuire T, Mook-Jung I, Ciechanover A, Xie XQ, Kim BY, Kwon YT. Regulation of autophagic proteolysis by the N-recognin SQSTM1/p62 of the N-end rule pathway. Autophagy. 1-6. PMID 29261001 DOI: 10.1080/15548627.2017.1415190 |
0.489 |
|
| 2017 |
Lee KH, Hwang JA, Kim SO, Kim JH, Shin SC, Kim EE, Lee KS, Rhee K, Jeon BH, Bang JK, Cha-Molstad H, Soung NK, Jang JH, Ko SK, Lee HG, ... ... Kwon YT, et al. Phosphorylation of human enhancer filamentation 1 (HEF1) stimulates interaction with Polo-like kinase 1 leading to HEF1 localization to focal adhesions. The Journal of Biological Chemistry. PMID 29191835 DOI: 10.1074/Jbc.M117.802587 |
0.337 |
|
| 2017 |
Kwon YT, Ciechanover A. The Ubiquitin Code in the Ubiquitin-Proteasome System and Autophagy. Trends in Biochemical Sciences. PMID 28947091 DOI: 10.1016/J.Tibs.2017.09.002 |
0.408 |
|
| 2017 |
Ji CH, Kwon YT. Crosstalk and Interplay between the Ubiquitin-Proteasome System and Autophagy. Molecules and Cells. PMID 28743182 DOI: 10.14348/Molcells.2017.0115 |
0.382 |
|
| 2017 |
Cha-Molstad H, Yu JE, Feng Z, Lee SH, Kim JG, Yang P, Han B, Sung KW, Yoo YD, Hwang J, McGuire T, Shim SM, Song HD, Ganipisetti S, Wang N, ... ... Kwon YT, et al. p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis. Nature Communications. 8: 102. PMID 28740232 DOI: 10.1038/S41467-017-00085-7 |
0.454 |
|
| 2017 |
Livneh I, Kravtsova-Ivantsiv Y, Braten O, Kwon YT, Ciechanover A. Monoubiquitination joins polyubiquitination as an esteemed proteasomal targeting signal. Bioessays : News and Reviews in Molecular, Cellular and Developmental Biology. PMID 28493408 DOI: 10.1002/Bies.201700027 |
0.369 |
|
| 2017 |
Ciechanover A, Kwon YT. Protein Quality Control by Molecular Chaperones in Neurodegeneration. Frontiers in Neuroscience. 11: 185. PMID 28428740 DOI: 10.3389/Fnins.2017.00185 |
0.355 |
|
| 2017 |
Sakchaisri K, Kim SO, Hwang J, Soung NK, Lee KH, Choi TW, Lee Y, Park CM, Thimmegowda NR, Lee PY, Shwetha B, Srinivasrao G, Pham TT, Jang JH, Yum HW, ... ... Kwon YT, et al. Anticancer activity of a novel small molecule tubulin inhibitor STK899704. Plos One. 12: e0173311. PMID 28296906 DOI: 10.1371/Journal.Pone.0173311 |
0.344 |
|
| 2017 |
Lee D, Oh SC, Kwon YT, Lee YJ, Yoo YD. Abstract 5327: Glioma derived cancer stem cells are hypersensitive to proteasomal inhibition Cancer Research. 77: 5327-5327. DOI: 10.1158/1538-7445.Am2017-5327 |
0.393 |
|
| 2016 |
Yoo YD, Lee DH, Cha-Molstad H, Kim H, Mun SR, Ji C, Park SH, Sung KS, Choi SA, Hwang J, Park DM, Kim SK, Park KJ, Kang SH, Oh SC, ... ... Kwon YT, et al. Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibition. Embo Reports. PMID 27993939 DOI: 10.15252/Embr.201642360 |
0.399 |
|
| 2016 |
Cohen-Kaplan V, Livneh I, Avni N, Fabre B, Ziv T, Kwon YT, Ciechanover A. p62- and ubiquitin-dependent stress-induced autophagy of the mammalian 26S proteasome. Proceedings of the National Academy of Sciences of the United States of America. PMID 27791183 DOI: 10.1073/Pnas.1615455113 |
0.39 |
|
| 2016 |
Jiang Y, Lee J, Lee JH, Lee JW, Kim JH, Choi WH, Yoo YD, Cha-Molstad H, Kim BY, Kwon YT, Noh SA, Kim KP, Lee MJ. The Arginylation Branch of the N-end Rule Pathway Positively Regulates Cellular Autophagic Flux and Clearance of Proteotoxic Proteins. Autophagy. 0. PMID 27560450 DOI: 10.1080/15548627.2016.1222991 |
0.499 |
|
| 2016 |
Braten O, Livneh I, Ziv T, Admon A, Kehat I, Caspi LH, Gonen H, Bercovich B, Godzik A, Jahandideh S, Jaroszewski L, Sommer T, Kwon YT, Guharoy M, Tompa P, et al. Numerous proteins with unique characteristics are degraded by the 26S proteasome following monoubiquitination. Proceedings of the National Academy of Sciences of the United States of America. PMID 27385826 DOI: 10.1073/Pnas.1608644113 |
0.386 |
|
| 2016 |
Kim E, Lee JH, Kwon YT, Lee MJ. Ablation of Arg-tRNA-Protein Transferases Results in Defective Neural Tube Development. Bmb Reports. PMID 27345715 DOI: 10.5483/Bmbrep.2016.49.8.087 |
0.385 |
|
| 2016 |
Lee YJ, Song X, Hong SH, Kwon WT, Bailey LM, Basse P, Bartlett DL, Kwon YT. Secretory TRAIL-armed Natural Killer Cell-based Therapy: In Vitro and In Vivo Colorectal Peritoneal Carcinomatosis Xenograft. Molecular Cancer Therapeutics. PMID 27196776 DOI: 10.1158/1535-7163.Mct-15-0937 |
0.348 |
|
| 2016 |
Kim SY, Hong SH, Basse PH, Wu C, Bartlett DL, Kwon YT, Lee YJ. Cancer Stem Cells Protect Non-Stem Cells from Anoikis: Bystander Effects. Journal of Cellular Biochemistry. PMID 26918647 DOI: 10.1002/Jcb.25527 |
0.327 |
|
| 2016 |
Klionsky DJ, Abdelmohsen K, Abe A, Abedin MJ, Abeliovich H, Acevedo Arozena A, Adachi H, Adams CM, Adams PD, Adeli K, Adhihetty PJ, Adler SG, Agam G, Agarwal R, Aghi MK, ... ... Kwon YT, et al. Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition). Autophagy. 12: 1-222. PMID 26799652 DOI: 10.1080/15548627.2015.1100356 |
0.351 |
|
| 2016 |
Cha-Molstad H, Yu JE, Lee SH, Kim JG, Sung KS, Hwang J, Yoo YD, Lee YJ, Kim ST, Lee DH, Ciechanover A, Kim BY, Kwon YT. Modulation of SQSTM1/p62 activity by N-terminal arginylation of the endoplasmic reticulum chaperone HSPA5/GRP78/BiP. Autophagy. 0. PMID 26797053 DOI: 10.1080/15548627.2015.1126047 |
0.506 |
|
| 2016 |
Kravtsova-Ivantsiv Y, Kwon YT, Ciechanover A. Role of the ubiquitin ligase KPC1 in NF-κB activation and tumor suppression Journal of Analytical Science and Technology. 7. DOI: 10.1186/S40543-016-0087-4 |
0.356 |
|
| 2015 |
Yoo YD, Kwon YT. Molecular mechanisms controlling asymmetric and symmetric self-renewal of cancer stem cells. Journal of Analytical Science and Technology. 6: 28. PMID 26495157 DOI: 10.1186/S40543-015-0071-4 |
0.31 |
|
| 2015 |
Lee JH, Jiang Y, Kwon YT, Lee MJ. Pharmacological Modulation of the N-End Rule Pathway and its Therapeutic Implications. Trends in Pharmacological Sciences. PMID 26434644 DOI: 10.1016/J.Tips.2015.07.004 |
0.44 |
|
| 2015 |
Song X, Dilly AK, Choudry HA, Bartlett DL, Kwon YT, Lee YJ. Hypoxia Promotes Synergy between Mitomycin C and Bortezomib through a Coordinated Process of Bcl-xL Phosphorylation and Mitochondrial Translocation of p53. Molecular Cancer Research : McR. PMID 26354682 DOI: 10.1158/1541-7786.Mcr-15-0237 |
0.356 |
|
| 2015 |
Cha-Molstad H, Kwon YT, Kim BY. Amino-terminal arginylation as a degradation signal for selective autophagy. Bmb Reports. PMID 26303972 DOI: 10.5483/Bmbrep.2015.48.9.176 |
0.483 |
|
| 2015 |
Lee DH, Sung KS, Guo ZS, Kwon WT, Bartlett DL, Oh SC, Kwon YT, Lee YJ. TRAIL-Induced Caspase Activation is a Prerequisite for Activation of the Endoplasmic Reticulum Stress-Induced Signal Transduction Pathways. Journal of Cellular Biochemistry. PMID 26212606 DOI: 10.1002/Jcb.25289 |
0.379 |
|
| 2015 |
Cha-Molstad H, Sung KS, Hwang J, Kim KA, Yu JE, Yoo YD, Jang JM, Han DH, Molstad M, Kim JG, Lee YJ, Zakrzewska A, Kim SH, Kim ST, Kim SY, ... ... Kwon YT, et al. Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding. Nature Cell Biology. 17: 917-29. PMID 26075355 DOI: 10.1038/Ncb3177 |
0.433 |
|
| 2015 |
Kravtsova-Ivantsiv Y, Shomer I, Cohen-Kaplan V, Snijder B, Superti-Furga G, Gonen H, Sommer T, Ziv T, Admon A, Naroditsky I, Jbara M, Brik A, Pikarsky E, Kwon YT, Doweck I, et al. KPC1-mediated ubiquitination and proteasomal processing of NF-κB1 p105 to p50 restricts tumor growth. Cell. 161: 333-47. PMID 25860612 DOI: 10.1016/J.Cell.2015.03.001 |
0.334 |
|
| 2015 |
Lee DH, Sung KS, Bartlett DL, Kwon YT, Lee YJ. HSP90 inhibitor NVP-AUY922 enhances TRAIL-induced apoptosis by suppressing the JAK2-STAT3-Mcl-1 signal transduction pathway in colorectal cancer cells. Cellular Signalling. 27: 293-305. PMID 25446253 DOI: 10.1016/J.Cellsig.2014.11.013 |
0.383 |
|
| 2014 |
Song X, Kim SY, Zhang L, Tang D, Bartlett DL, Kwon YT, Lee YJ. Role of AMP-activated protein kinase in cross-talk between apoptosis and autophagy in human colon cancer. Cell Death & Disease. 5: e1504. PMID 25356873 DOI: 10.1038/Cddis.2014.463 |
0.391 |
|
| 2014 |
Kim SY, Lee DH, Song X, Bartlett DL, Kwon YT, Lee YJ. Role of Bcl-xL/Beclin-1 in synergistic apoptotic effects of secretory TRAIL-armed adenovirus in combination with mitomycin C and hyperthermia on colon cancer cells. Apoptosis : An International Journal On Programmed Cell Death. 19: 1603-15. PMID 25156145 DOI: 10.1007/S10495-014-1028-6 |
0.353 |
|
| 2013 |
Boso G, Tasaki T, Kwon YT, Somia NV. The N-end rule and retroviral infection: no effect on integrase. Virology Journal. 10: 233. PMID 23849394 DOI: 10.1186/1743-422X-10-233 |
0.413 |
|
| 2013 |
Kim ST, Tasaki T, Zakrzewska A, Yoo YD, Sung KS, Kim S, Cha-Molstad H, Hwang J, Kim KA, Kim BY, Kwon YT. The N-end rule proteolytic system in autophagy Autophagy. 9: 1100-1103. PMID 23628846 DOI: 10.4161/Auto.24643 |
0.477 |
|
| 2013 |
Song X, Kim SY, Zhou Z, Lagasse E, Kwon YT, Lee YJ. Hyperthermia enhances mapatumumab-induced apoptotic death through ubiquitin-mediated degradation of cellular FLIP(long) in human colon cancer cells. Cell Death & Disease. 4: e577. PMID 23559011 DOI: 10.1038/Cddis.2013.104 |
0.339 |
|
| 2013 |
Tasaki T, Kim ST, Zakrzewska A, Lee BE, Kang MJ, Yoo YD, Cha-Molstad HJ, Hwang J, Soung NK, Sung KS, Kim SH, Nguyen MD, Sun M, Yi EC, Kim BY, ... Kwon YT, et al. UBR box N-recognin-4 (UBR4), an N-recognin of the N-end rule pathway, and its role in yolk sac vascular development and autophagy. Proceedings of the National Academy of Sciences of the United States of America. 110: 3800-5. PMID 23431188 DOI: 10.1073/Pnas.1217358110 |
0.484 |
|
| 2013 |
Kim SO, Sakchaisri K, Thimmegowda NR, N R T, Soung NK, Jang JH, Kim YS, Lee KS, Kwon YT, Asami Y, Ahn JS, Erikson RL, Kim BY. STK295900, a dual inhibitor of topoisomerase 1 and 2, induces G(2) arrest in the absence of DNA damage. Plos One. 8: e53908. PMID 23349762 DOI: 10.1371/Journal.Pone.0053908 |
0.302 |
|
| 2013 |
He L, Jang JH, Choi HG, Lee SM, Nan MH, Jeong SJ, Dong Z, Kwon YT, Lee KS, Lee KW, Chung JK, Ahn JS, Kim BY. Oligomycin A enhances apoptotic effect of TRAIL through CHOP-mediated death receptor 5 expression. Molecular Carcinogenesis. 52: 85-93. PMID 23335397 DOI: 10.1002/Mc.21831 |
0.393 |
|
| 2013 |
Kim SY, Kang JW, Song X, Kim BK, Yoo YD, Kwon YT, Lee YJ. Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells. Cellular Signalling. 25: 961-9. PMID 23333246 DOI: 10.1016/J.Cellsig.2013.01.007 |
0.302 |
|
| 2013 |
Huong PT, Soung NK, Jang JH, Cha-Molstad HJ, Sakchaisri K, Kim SO, Jang JM, Kim KE, Lee KS, Kwon YT, Erikson RL, Ahn JS, Kim BY. Regulation of CEP131 gene expression by SP1. Gene. 513: 75-81. PMID 23137637 DOI: 10.1016/J.Gene.2012.10.074 |
0.335 |
|
| 2012 |
An JY, Kim E, Zakrzewska A, Yoo YD, Jang JM, Han DH, Lee MJ, Seo JW, Lee YJ, Kim TY, de Rooij DG, Kim BY, Kwon YT. UBR2 of the N-end rule pathway is required for chromosome stability via histone ubiquitylation in spermatocytes and somatic cells. Plos One. 7: e37414. PMID 22616001 DOI: 10.1371/Journal.Pone.0037414 |
0.44 |
|
| 2012 |
Lee MJ, Kim DE, Zakrzewska A, Yoo YD, Kim SH, Kim ST, Seo JW, Lee YS, Dorn GW, Oh U, Kim BY, Kwon YT. Characterization of arginylation branch of N-end rule pathway in G-protein-mediated proliferation and signaling of cardiomyocytes. The Journal of Biological Chemistry. 287: 24043-52. PMID 22577142 DOI: 10.1074/Jbc.M112.364117 |
0.422 |
|
| 2012 |
Tasaki T, Sriram SM, Park KS, Kwon YT. The N-end rule pathway. Annual Review of Biochemistry. 81: 261-89. PMID 22524314 DOI: 10.1146/Annurev-Biochem-051710-093308 |
0.453 |
|
| 2012 |
Kwon O, Soung NK, Thimmegowda NR, Jeong SJ, Jang JH, Moon DO, Chung JK, Lee KS, Kwon YT, Erikson RL, Ahn JS, Kim BY. Patulin induces colorectal cancer cells apoptosis through EGR-1 dependent ATF3 up-regulation. Cellular Signalling. 24: 943-50. PMID 22230687 DOI: 10.1016/J.Cellsig.2011.12.017 |
0.362 |
|
| 2012 |
Meisenberg C, Tait PS, Dianova II, Wright K, Edelmann MJ, Ternette N, Tasaki T, Kessler BM, Parsons JL, Kwon YT, Dianov GL. Ubiquitin ligase UBR3 regulates cellular levels of the essential DNA repair protein APE1 and is required for genome stability. Nucleic Acids Research. 40: 701-11. PMID 21933813 DOI: 10.1093/Nar/Gkr744 |
0.36 |
|
| 2011 |
Sriram SM, Kim BY, Kwon YT. The N-end rule pathway: emerging functions and molecular principles of substrate recognition. Nature Reviews. Molecular Cell Biology. 12: 735-47. PMID 22016057 DOI: 10.1038/Nrm3217 |
0.478 |
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| 2010 |
Yang F, Cheng Y, An JY, Kwon YT, Eckardt S, Leu NA, McLaughlin KJ, Wang PJ. The ubiquitin ligase Ubr2, a recognition E3 component of the N-end rule pathway, stabilizes Tex19.1 during spermatogenesis. Plos One. 5: e14017. PMID 21103378 DOI: 10.1371/Journal.Pone.0014017 |
0.499 |
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| 2010 |
Sriram SM, Kwon YT. The molecular principles of N-end rule recognition. Nature Structural & Molecular Biology. 17: 1164-5. PMID 20924402 DOI: 10.1038/Nsmb1010-1164 |
0.414 |
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| 2010 |
An JY, Kim EA, Jiang Y, Zakrzewska A, Kim DE, Lee MJ, Mook-Jung I, Zhang Y, Kwon YT. UBR2 mediates transcriptional silencing during spermatogenesis via histone ubiquitination. Proceedings of the National Academy of Sciences of the United States of America. 107: 1912-7. PMID 20080676 DOI: 10.1073/Pnas.0910267107 |
0.315 |
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| 2009 |
Sriram SM, Banerjee R, Kane RS, Kwon YT. Multivalency-Assisted Control of Intracellular Signaling Pathways: Application for Ubiquitin- Dependent N-End Rule Pathway Chemistry and Biology. 16: 121-131. PMID 19246002 DOI: 10.1016/J.Chembiol.2009.01.012 |
0.445 |
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| 2009 |
Jeong JH, An JY, Kwon YT, Rhee JG, Lee YJ. Effects of low dose quercetin: Cancer cell-specific inhibition of cell cycle progression Journal of Cellular Biochemistry. 106: 73-82. PMID 19009557 DOI: 10.1002/Jcb.21977 |
0.329 |
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| 2009 |
Tasaki T, Zakrzewska A, Dudgeon DD, Jiang Y, Lazo JS, Kwon YT. The substrate recognition domains of the N-end rule pathway. Journal of Biological Chemistry. 284: 1884-1895. PMID 19008229 DOI: 10.1074/Jbc.M803641200 |
0.431 |
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| 2008 |
Lee MJ, Pal K, Tasaki T, Roy S, Jiang Y, An JY, Banerjee R, Kwon YT. Synthetic heterovalent inhibitors targeting recognition E3 components of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 105: 100-5. PMID 18162545 DOI: 10.1073/Pnas.0708465105 |
0.455 |
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| 2007 |
Tasaki T, Kwon YT. The mammalian N-end rule pathway: new insights into its components and physiological roles Trends in Biochemical Sciences. 32: 520-528. PMID 17962019 DOI: 10.1016/J.Tibs.2007.08.010 |
0.459 |
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| 2007 |
Tasaki T, Sohr R, Xia Z, Hellweg R, Hörtnagl H, Varshavsky A, Kwon YT. Biochemical and genetic studies of UBR3, a ubiquitin ligase with a function in olfactory and other sensory systems. The Journal of Biological Chemistry. 282: 18510-20. PMID 17462990 DOI: 10.1074/Jbc.M701894200 |
0.433 |
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| 2006 |
Hu RG, Brower CS, Wang H, Davydov IV, Sheng J, Zhou J, Kwon YT, Varshavsky A. Arginyltransferase, its specificity, putative substrates, bidirectional promoter, and splicing-derived isoforms. The Journal of Biological Chemistry. 281: 32559-73. PMID 16943202 DOI: 10.1074/Jbc.M604355200 |
0.486 |
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| 2006 |
An JY, Seo JW, Tasaki T, Lee MJ, Varshavsky A, Kwon YT. Impaired neurogenesis and cardiovascular development in mice lacking the E3 ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 103: 6212-7. PMID 16606826 DOI: 10.1073/Pnas.0601700103 |
0.466 |
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| 2006 |
Ouyang Y, Kwon YT, An JY, Eller D, Tsai SC, Diaz-Perez S, Troke JJ, Teitell MA, Marahrens Y. Loss of Ubr2, an E3 ubiquitin ligase, leads to chromosome fragility and impaired homologous recombinational repair. Mutation Research. 596: 64-75. PMID 16488448 DOI: 10.1016/J.Mrfmmm.2005.12.016 |
0.38 |
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| 2006 |
Zenker M, Mayerle J, Lerch MM, Tagariello A, Zerres K, Durie PR, Beier M, Hülskamp G, Guzman C, Rehder H, Beemer FA, Hamel B, Vanlieferinghen P, Gershoni-Baruch R, Vieira MW, ... ... Kwon Y, et al. Erratum: Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome) (Nature Genetics (2005) 37 (1345-1350)) Nature Genetics. 38. DOI: 10.1038/Ng0206-265 |
0.333 |
|
| 2005 |
Zenker M, Mayerle J, Lerch MM, Tagariello A, Zerres K, Durie PR, Beier M, Hülskamp G, Guzman C, Rehder H, Beemer FA, Hamel B, Vanlieferinghen P, Gershoni-Baruch R, Vieira MW, ... ... Kwon YT, et al. Deficiency of UBR1, a ubiquitin ligase of the N-end rule pathway, causes pancreatic dysfunction, malformations and mental retardation (Johanson-Blizzard syndrome). Nature Genetics. 37: 1345-50. PMID 16311597 DOI: 10.1038/Ng1681 |
0.379 |
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| 2005 |
Lee MJ, Tasaki T, Moroi K, An JY, Kimura S, Davydov IV, Kwon YT. RGS4 and RGS5 are in vivo substrates of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 102: 15030-5. PMID 16217033 DOI: 10.1073/Pnas.0507533102 |
0.485 |
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| 2005 |
Kim KM, Song JJ, An JY, Kwon YT, Lee YJ. Pretreatment of acetylsalicylic acid promotes tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis by down-regulating BCL-2 gene expression Journal of Biological Chemistry. 280: 41047-41056. PMID 16199534 DOI: 10.1074/Jbc.M503713200 |
0.354 |
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| 2005 |
Tasaki T, Mulder LC, Iwamatsu A, Lee MJ, Davydov IV, Varshavsky A, Muesing M, Kwon YT. A family of mammalian E3 ubiquitin ligases that contain the UBR box motif and recognize N-degrons. Molecular and Cellular Biology. 25: 7120-36. PMID 16055722 DOI: 10.1128/Mcb.25.16.7120-7136.2005 |
0.469 |
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| 2004 |
Baumeister W, Bachmair A, Chau V, Cohen R, Coffino P, Demartino G, Deshaies R, Dohmen J, Emr S, Finley D, Hampton R, Hill C, Hochstrasser M, Huber R, Jackson P, ... ... Kwon YT, et al. Varshavsky's contributions. Science (New York, N.Y.). 306: 1290-2. PMID 15550643 DOI: 10.1126/Science.306.5700.1290 |
0.341 |
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| 2004 |
Yin J, Kwon YT, Varshavsky A, Wang W. RECQL4, mutated in the Rothmund-Thomson and RAPADILINO syndromes, interacts with ubiquitin ligases UBR1 and UBR2 of the N-end rule pathway. Human Molecular Genetics. 13: 2421-30. PMID 15317757 DOI: 10.1093/Hmg/Ddh269 |
0.442 |
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| 2003 |
Kwon YT, Xia Z, An JY, Tasaki T, Davydov IV, Seo JW, Sheng J, Xie Y, Varshavsky A. Female lethality and apoptosis of spermatocytes in mice lacking the UBR2 ubiquitin ligase of the N-end rule pathway. Molecular and Cellular Biology. 23: 8255-71. PMID 14585983 DOI: 10.1128/Mcb.23.22.8255-8271.2003 |
0.439 |
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| 2002 |
Kwon YT, Kashina AS, Davydov IV, Hu RG, An JY, Seo JW, Du F, Varshavsky A. An essential role of N-terminal arginylation in cardiovascular development. Science (New York, N.Y.). 297: 96-9. PMID 12098698 DOI: 10.1126/Science.1069531 |
0.45 |
|
| 2001 |
Kwon YT, Xia Z, Davydov IV, Lecker SH, Varshavsky A. Construction and analysis of mouse strains lacking the ubiquitin ligase UBR1 (E3alpha) of the N-end rule pathway. Molecular and Cellular Biology. 21: 8007-21. PMID 11689692 DOI: 10.1128/Mcb.21.23.8007-8021.2001 |
0.475 |
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| 2000 |
Balogh SA, Kwon YT, Denenberg VH. Varying intertrial interval reveals temporally defined memory deficits and enhancements in NTAN1-deficient mice. Learning & Memory (Cold Spring Harbor, N.Y.). 7: 279-86. PMID 11040259 DOI: 10.1101/Lm.33500 |
0.352 |
|
| 2000 |
Kwon YT, Balogh SA, Davydov IV, Kashina AS, Yoon JK, Xie Y, Gaur A, Hyde L, Denenberg VH, Varshavsky A. Altered activity, social behavior, and spatial memory in mice lacking the NTAN1p amidase and the asparagine branch of the N-end rule pathway. Molecular and Cellular Biology. 20: 4135-48. PMID 10805755 DOI: 10.1128/Mcb.20.11.4135-4148.2000 |
0.433 |
|
| 1999 |
Lecker SH, Solomon V, Price SR, Kwon YT, Mitch WE, Goldberg AL. Ubiquitin conjugation by the N-end rule pathway and mRNAs for its components increase in muscles of diabetic rats. Journal of Clinical Investigation. 104: 1411-1420. PMID 10562303 DOI: 10.1172/Jci7300 |
0.326 |
|
| 1999 |
Kwon YT, Lévy F, Varshavsky A. Bivalent inhibitor of the N-end rule pathway. The Journal of Biological Chemistry. 274: 18135-9. PMID 10364269 DOI: 10.1074/Jbc.274.25.18135 |
0.433 |
|
| 1999 |
Kwon YT, Kashina AS, Varshavsky A. Alternative splicing results in differential expression, activity, and localization of the two forms of arginyl-tRNA-protein transferase, a component of the N-end rule pathway. Molecular and Cellular Biology. 19: 182-93. PMID 9858543 DOI: 10.1128/Mcb.19.1.182 |
0.433 |
|
| 1998 |
Kwon YT, Reiss Y, Fried VA, Hershko A, Yoon JK, Gonda DK, Sangan P, Copeland NG, Jenkins NA, Varshavsky A. The mouse and human genes encoding the recognition component of the N-end rule pathway. Proceedings of the National Academy of Sciences of the United States of America. 95: 7898-903. PMID 9653112 DOI: 10.1073/Pnas.95.14.7898 |
0.447 |
|
| 1996 |
Grigoryev S, Stewart AE, Kwon YT, Arfin SM, Bradshaw RA, Jenkins NA, Copeland NG, Varshavsky A. A mouse amidase specific for N-terminal asparagine. The gene, the enzyme, and their function in the N-end rule pathway. The Journal of Biological Chemistry. 271: 28521-32. PMID 8910481 DOI: 10.1074/Jbc.271.45.28521 |
0.429 |
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