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Feng Zhang - Publications

Affiliations: 
2005-2008 Plant Biology University of Georgia, Athens, Athens, GA, United States 
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263 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zhang F, Wang JY, Li CL, Zhang WG. HyCas9-12aGEP: an efficient genome editing platform for . Frontiers in Bioengineering and Biotechnology. 12: 1327172. PMID 38532881 DOI: 10.3389/fbioe.2024.1327172  0.301
2024 Vats S, Kumar J, Sonah H, Zhang F, Deshmukh R. Prime Editing in Plants: Prospects and Challenges. Journal of Experimental Botany. PMID 38366636 DOI: 10.1093/jxb/erae053  0.305
2023 Lei W, Zhu H, Cao M, Zhang F, Lai Q, Lu S, Dong W, Sun J, Ru D. From genomics to metabolomics: Deciphering sanguinarine biosynthesis in Dicranostigma leptopodum. International Journal of Biological Macromolecules. 128727. PMID 38092109 DOI: 10.1016/j.ijbiomac.2023.128727  0.348
2023 Yan B, Di X, Yang M, Wu H, Yu X, Zhang F. Chromosome-Scale Genome Assembly of The Solitary Parasitoid Wasp Microplitis manilae Ashmead, 1904 (Braconidae: Microgastrinae). Genome Biology and Evolution. PMID 37515590 DOI: 10.1093/gbe/evad144  0.304
2023 Kumar J, Char SN, Weiss T, Liu H, Liu B, Yang B, Zhang F. Efficient protein tagging and cis-regulatory element engineering via precise and directional oligonucleotide-based targeted insertion in plants. The Plant Cell. PMID 37191128 DOI: 10.1093/plcell/koad139  0.338
2023 Bustos FJ, Pandian S, Haensgen H, Zhao JP, Strouf H, Heidenreich M, Swiech L, Deverman B, Gradinaru V, Zhang F, Constantine-Paton M. Removal of a genomic duplication by double-nicking CRISPR restores synaptic transmission and behavior in the MyosinVA mutant mouse Flailer. Biorxiv : the Preprint Server For Biology. PMID 37163068 DOI: 10.1101/2023.04.28.538685  0.312
2023 Chamness JC, Kumar J, Cruz AJ, Rhuby E, Holum MJ, Cody JP, Tibebu R, Gamo ME, Starker CG, Zhang F, Voytas DF. An extensible vector toolkit and parts library for advanced engineering of plant genomes. The Plant Genome. e20312. PMID 36896468 DOI: 10.1002/tpg2.20312  0.602
2022 An Y, Zhang X, Jiang S, Zhao J, Zhang F. TeaPVs: a comprehensive genomic variation database for tea plant (Camellia sinensis). Bmc Plant Biology. 22: 513. PMID 36324064 DOI: 10.1186/s12870-022-03901-5  0.353
2022 Quan ZJ, Li SA, Yang ZX, Zhao JJ, Li GH, Zhang F, Wen W, Cheng T, Zhang XB. GREPore-seq: A robust workflow to detect changes after gene editing through long-range PCR and nanopore sequencing. Genomics, Proteomics & Bioinformatics. PMID 35752289 DOI: 10.1016/j.gpb.2022.06.002  0.332
2022 Read A, Weiss T, Crisp PA, Liang Z, Noshay J, Menard CC, Wang C, Song M, Hirsch CN, Springer NM, Zhang F. Genome-wide loss of CHH methylation with limited transcriptome changes in Setaria viridis domains rearranged methyltransferase (DRM) mutants. The Plant Journal : For Cell and Molecular Biology. PMID 35436373 DOI: 10.1111/tpj.15781  0.302
2022 Patil GB, Stupar RM, Zhang F. Protoplast Isolation, Transfection, and Gene Editing for Soybean (Glycine max ). Methods in Molecular Biology (Clifton, N.J.). 2464: 173-186. PMID 35258833 DOI: 10.1007/978-1-0716-2164-6_13  0.34
2022 Banakar R, Rai KM, Zhang F. CRISPR DNA- and RNP-Mediated Genome Editing via Nicotiana benthamiana Protoplast Transformation and Regeneration. Methods in Molecular Biology (Clifton, N.J.). 2464: 65-82. PMID 35258825 DOI: 10.1007/978-1-0716-2164-6_5  0.306
2022 Fu J, Fu YW, Zhao JJ, Yang ZX, Li SA, Li GH, Quan ZJ, Zhang F, Zhang JP, Zhang XB, Sun CK. Improved and Flexible HDR Editing by Targeting Introns in iPSCs. Stem Cell Reviews and Reports. PMID 35089463 DOI: 10.1007/s12015-022-10331-1  0.323
2021 Cable J, Ronald PC, Voytas D, Zhang F, Levy AA, Takatsuka A, Arimura SI, Jacobsen SE, Toki S, Toda E, Gao C, Zhu JK, Boch J, Van Eck J, Mahfouz M, et al. Plant genome engineering from lab to field-a Keystone Symposia report. Annals of the New York Academy of Sciences. PMID 34435370 DOI: 10.1111/nyas.14675  0.554
2020 Gao L, Altae-Tran H, Böhning F, Makarova KS, Segel M, Schmid-Burgk JL, Koob J, Wolf YI, Koonin EV, Zhang F. Diverse enzymatic activities mediate antiviral immunity in prokaryotes. Science (New York, N.Y.). 369: 1077-1084. PMID 32855333 DOI: 10.1126/Science.Aba0372  0.363
2020 MacKay MJ, Hooker AC, Afshinnekoo E, Salit M, Kelly J, Feldstein JV, Haft N, Schenkel D, Nambi S, Cai Y, Zhang F, Church G, Dai J, Wang CL, Levy S, et al. The COVID-19 XPRIZE and the need for scalable, fast, and widespread testing. Nature Biotechnology. PMID 32820257 DOI: 10.1038/S41587-020-0655-4  0.478
2020 Li P, Ning Y, Wang W, Guo X, Poulet B, Wang X, Wen Y, Han J, Hao J, Liang X, Liu L, Du Y, Cheng B, Cheng S, Zhang L, ... Zhang F, et al. The integrative analysis of DNA methylation and mRNA expression profiles confirmed the role of selenocompound metabolism pathway in Kashin-Beck disease. Cell Cycle (Georgetown, Tex.). 1-16. PMID 32816579 DOI: 10.1080/15384101.2020.1807665  0.316
2020 Weiss T, Wang C, Kang X, Zhao H, Gamo ME, Starker CG, Crisp PA, Zhou P, Springer NM, Voytas DF, Zhang F. Optimization of multiplexed CRISPR/Cas9 system for highly efficient genome editing in Setaria viridis. The Plant Journal : For Cell and Molecular Biology. PMID 32786122 DOI: 10.1111/Tpj.14949  0.647
2020 Jin S, Fei H, Zhu Z, Luo Y, Liu J, Gao S, Zhang F, Chen YH, Wang Y, Gao C. Rationally Designed APOBEC3B Cytosine Base Editors with Improved Specificity. Molecular Cell. PMID 32721385 DOI: 10.1016/J.Molcel.2020.07.005  0.398
2020 Schmid-Burgk JL, Gao L, Li D, Gardner Z, Strecker J, Lash B, Zhang F. Highly Parallel Profiling of Cas9 Variant Specificity. Molecular Cell. PMID 32187529 DOI: 10.1016/J.Molcel.2020.02.023  0.383
2020 Sun X, Ding Y, Orr MC, Zhang F. Streamlining universal single-copy ortholog and ultraconserved element design: a case study in Collembola. Molecular Ecology Resources. PMID 32065730 DOI: 10.1111/1755-0998.13146  0.391
2019 Zhang F, Voytas DF. Modulating gene translational control through genome editing. National Science Review. 6: 391. PMID 34691885 DOI: 10.1093/nsr/nwy123  0.568
2019 Liu C, He X, Liu W, Yang S, Wang L, Li W, Wu H, Tang S, Ni X, Wang J, Gao Y, Tian S, Zhang L, Cong J, Zhang Z, ... Zhang F, et al. Bi-allelic Mutations in TTC29 Cause Male Subfertility with Asthenoteratospermia in Humans and Mice. American Journal of Human Genetics. PMID 31735294 DOI: 10.1016/J.Ajhg.2019.10.010  0.303
2019 Zetsche B, Strecker J, Abudayyeh OO, Gootenberg JS, Scott DA, Zhang F. A Survey of Genome Editing Activity for 16 Cas12a Orthologs. The Keio Journal of Medicine. PMID 31723075 DOI: 10.2302/Kjm.2019-0009-Oa  0.353
2019 Zhang B, Ma H, Khan T, Ma A, Li T, Zhang H, Gao J, Zhou J, Li Y, Yu C, Bao J, Ali A, Murtaza G, Yin H, Gao Q, ... Zhang F, et al. A missense variant causes flagella destabilization and asthenozoospermia. The Journal of Experimental Medicine. PMID 31658987 DOI: 10.1084/Jem.20182365  0.314
2019 Zhang L, Du Y, Wen Y, Ma M, Cheng S, Cheng B, Li P, Qi X, Liang C, Liu L, Liang X, Guo X, Zhang F. Integrating transcriptome-wide association study and mRNA expression profiling identified candidate genes and pathways associated with osteomyelitis. Scandinavian Journal of Rheumatology. 1-6. PMID 31657276 DOI: 10.1080/03009742.2019.1653492  0.351
2019 Yang X, Zhang X, Jiao J, Zhang F, Pan Y, Wang Q, Chen Q, Cai B, Tang S, Zhou Z, Chen S, Yin H, Fu W, Luo Y, Li D, et al. Rare variants in FANCA induce premature ovarian insufficiency. Human Genetics. PMID 31535215 DOI: 10.1007/S00439-019-02059-9  0.321
2019 Wang Y, Wu C, Zhang F, Zhang Y, Ren Z, Lammi MJ, Guo X. Screening for Differentially Expressed Circular RNAs in the Cartilage of Osteoarthritis Patients for Their Diagnostic Value. Genetic Testing and Molecular Biomarkers. PMID 31502887 DOI: 10.1089/Gtmb.2019.0108  0.314
2019 Chen W, Lin J, Wang L, Li X, Zhao S, Liu J, Akdemir ZC, Zhao Y, Du R, Ye Y, Song X, Zhang Y, Yan Z, Yang X, Lin M, ... ... Zhang F, et al. TBX6 missense variants expand the mutational spectrum in a non-Mendelian inheritance disease. Human Mutation. PMID 31471994 DOI: 10.1002/Humu.23907  0.341
2019 Hijazi H, Coelho FS, Gonzaga-Jauregui C, Bernardini L, Mar SS, Manning MA, Hanson-Kahn A, Naidu S, Srivastava S, Lee JA, Jones JR, Friez MJ, Alberico T, Torres B, Fang P, ... ... Zhang F, et al. Xq22 deletions and correlation with distinct neurological disease traits in females: further evidence for a contiguous gene syndrome. Human Mutation. PMID 31448840 DOI: 10.1002/Humu.23902  0.386
2019 Qi X, Guan F, Wen Y, Li P, Ma M, Cheng S, Zhang L, Liang C, Cheng B, Zhang F. Integrating genome-wide association study and methylation functional annotation data identified candidate genes and pathways for schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. 109736. PMID 31425724 DOI: 10.1016/J.Pnpbp.2019.109736  0.307
2019 Wu J, Du Y, Song J, Dang X, Wang K, Wen Y, Zhang F, Liu R. Genome-wide DNA methylation profiling of hip articular cartilage identifies differentially methylated loci associated with osteonecrosis of the femoral head. Bone. PMID 31233934 DOI: 10.1016/J.Bone.2019.06.021  0.304
2019 Li P, Wu C, Guo X, Wen Y, Liu L, Liang X, Du Y, Zhang L, Ma M, Cheng S, Cheng B, Wang S, Zhang F. Integrative Analysis of Genome-Wide Association Studies and DNA Methylation Profile Identified Genetic Control Genes of DNA Methylation for Kashin-Beck Disease. Cartilage. 1947603519858748. PMID 31220921 DOI: 10.1177/1947603519858748  0.324
2019 Strecker J, Ladha A, Gardner Z, Schmid-Burgk JL, Makarova KS, Koonin EV, Zhang F. RNA-guided DNA insertion with CRISPR-associated transposases. Science (New York, N.Y.). PMID 31171706 DOI: 10.1126/Science.Aax9181  0.31
2019 Zhang L, Liu L, Ma M, Cheng S, Cheng B, Li P, Wen Y, Du Y, Liang X, Zhao Y, Ding M, Xin Q, Liang C, Huang H, Zhang F. Integrative analysis of transcriptome-wide association study data and mRNA expression profiles identified candidate genes and pathways associated with atrial fibrillation. Heart and Vessels. PMID 31065785 DOI: 10.1007/S00380-019-01418-W  0.331
2019 Hirano S, Abudayyeh OO, Gootenberg JS, Horii T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O. Structural basis for the promiscuous PAM recognition by Corynebacterium diphtheriae Cas9. Nature Communications. 10: 1968. PMID 31036811 DOI: 10.1038/s41467-019-09741-6  0.301
2019 Cheng B, Liang X, Wen Y, Li P, Zhang L, Ma M, Cheng S, Du Y, Liu L, Ding M, Zhao Y, Zhang F. Integrative analysis of transcriptome-wide association study data and messenger RNA expression profiles identified candidate genes and pathways for inflammatory bowel disease. Journal of Cellular Biochemistry. PMID 31009124 DOI: 10.1002/Jcb.28744  0.316
2019 Ma M, Huang DG, Liang X, Zhang L, Cheng S, Cheng B, Qi X, Li P, Du Y, Liu L, Zhao Y, Ding M, Wen Y, Guo X, Zhang F. Integrating transcriptome-wide association study and mRNA expression profiling identifies novel genes associated with bone mineral density. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 30993394 DOI: 10.1007/S00198-019-04958-Z  0.311
2019 Liu W, He X, Yang S, Zouari R, Wang J, Wu H, Kherraf ZE, Liu C, Coutton C, Zhao R, Tang D, Tang S, Lv M, Fang Y, Li W, ... ... Zhang F, et al. Bi-allelic Mutations in TTC21A Induce Asthenoteratospermia in Humans and Mice. American Journal of Human Genetics. PMID 30929735 DOI: 10.1016/J.Ajhg.2019.02.020  0.315
2019 Jin S, Zong Y, Gao Q, Zhu Z, Wang Y, Qin P, Liang C, Wang D, Qiu JL, Zhang F, Gao C. Cytosine, but not adenine, base editors induce genome-wide off-target mutations in rice. Science (New York, N.Y.). PMID 30819931 DOI: 10.1126/Science.Aaw7166  0.396
2019 Coutton C, Martinez G, Kherraf ZE, Amiri-Yekta A, Boguenet M, Saut A, He X, Zhang F, Cristou-Kent M, Escoffier J, Bidart M, Satre V, Conne B, Fourati Ben Mustapha S, Halouani L, et al. Bi-allelic Mutations in ARMC2 Lead to Severe Astheno-Teratozoospermia Due to Sperm Flagellum Malformations in Humans and Mice. American Journal of Human Genetics. PMID 30686508 DOI: 10.1016/J.Ajhg.2018.12.013  0.322
2019 Strecker J, Jones S, Koopal B, Schmid-Burgk J, Zetsche B, Gao L, Makarova KS, Koonin EV, Zhang F. Engineering of CRISPR-Cas12b for human genome editing. Nature Communications. 10: 212. PMID 30670702 DOI: 10.1038/S41467-018-08224-4  0.378
2019 Zhang F, Ding Y, Zhou QS, Wu J, Luo A, Zhu CD. A high-quality draft genome assembly of Sinella curviseta, a soil model organism (Collembola). Genome Biology and Evolution. PMID 30668671 DOI: 10.1093/Gbe/Evz013  0.348
2019 Dong S, Wang C, Li X, Shen Q, Fu X, Wu M, Song C, Yang N, Wu Y, Wang H, Jin L, Xu H, Zhang F. Noncoding rare variants of TBX6 in congenital anomalies of the kidney and urinary tract. Molecular Genetics and Genomics : Mgg. PMID 30604070 DOI: 10.1007/S00438-018-1522-6  0.311
2019 Wang Q, Li D, Cai B, Chen Q, Li C, Wu Y, Jin L, Wang X, Zhang X, Zhang F. Whole-exome sequencing reveals SALL4 variants in premature ovarian insufficiency: an update on genotype-phenotype correlations. Human Genetics. PMID 30603774 DOI: 10.1007/S00439-018-1962-4  0.34
2019 Zhang F. Biology and Application of Genome Editing Blood. 134. DOI: 10.1182/Blood-2019-121282  0.331
2018 Huang H, Cheng S, Ding M, Wen Y, Ma M, Zhang L, Li P, Cheng B, Liang X, Liu L, Du Y, Zhao Y, Kafle OP, Han B, Zhang F. Integrative Analysis of Transcriptome-Wide Association Study and mRNA Expression Profiles Identifies Candidate Genes Associated With Autism Spectrum Disorders. Autism Research : Official Journal of the International Society For Autism Research. PMID 30561910 DOI: 10.1002/Aur.2048  0.329
2018 Ji X, Si X, Zhang Y, Zhang H, Zhang F, Gao C. Conferring DNA virus resistance with high specificity in plants using virus-inducible genome-editing system. Genome Biology. 19: 197. PMID 30442181 DOI: 10.1186/S13059-018-1580-4  0.322
2018 He X, Li W, Wu H, Lv M, Liu W, Liu C, Zhu F, Li C, Fang Y, Yang C, Cheng H, Zhang J, Tan J, Chen T, Tang D, ... ... Zhang F, et al. Novel homozygous mutations in humans and mice cause severe asthenoteratospermia with multiple morphological abnormalities of the sperm flagella. Journal of Medical Genetics. PMID 30415212 DOI: 10.1136/Jmedgenet-2018-105486  0.315
2018 Gao K, Zhang Y, Zhang L, Kong W, Xie H, Wang J, Wu Y, Wu X, Liu X, Zhang Y, Zhang F, Yu AC, Jiang Y. Large De Novo Microdeletion in Epilepsy with Intellectual and Developmental Disabilities, with a Systems Biology Analysis. Advances in Neurobiology. 21: 247-266. PMID 30334225 DOI: 10.1007/978-3-319-94593-4_9  0.32
2018 Li W, He X, Yang S, Liu C, Wu H, Liu W, Lv M, Tang D, Tan J, Tang S, Chen Y, Wang J, Zhang Z, Wang H, Jin L, ... Zhang F, et al. Biallelic mutations of CFAP251 cause sperm flagellar defects and human male infertility. Journal of Human Genetics. PMID 30310178 DOI: 10.1038/S10038-018-0520-1  0.334
2018 Yang N, Wu N, Zhang L, Zhao Y, Liu J, Liang X, Ren X, Li W, Chen W, Dong S, Zhao S, Lin J, Xiang H, Xue H, Chen L, ... ... Zhang F, et al. TBX6 compound inheritance leads to congenital vertebral malformations in humans and mice. Human Molecular Genetics. PMID 30307510 DOI: 10.1093/Hmg/Ddy358  0.315
2018 Nishimasu H, Shi X, Ishiguro S, Gao L, Hirano S, Okazaki S, Noda T, Abudayyeh OO, Gootenberg JS, Mori H, Oura S, Holmes B, Tanaka M, Seki M, Hirano H, ... ... Zhang F, et al. Engineered CRISPR-Cas9 nuclease with expanded targeting space. Science (New York, N.Y.). PMID 30166441 DOI: 10.1126/Science.Aas9129  0.341
2018 Zhang F, Voytas DF. Synthetic genomes engineered by SCRaMbLEing. Science China. Life Sciences. PMID 29951952 DOI: 10.1007/S11427-018-9325-1  0.576
2018 He A, Ning Y, Wen Y, Cai Y, Xu K, Cai Y, Han J, Liu L, Du Y, Liang X, Li P, Fan Q, Hao J, Wang X, Guo X, ... Zhang F, et al. Use of integrative epigenetic and mRNA expression analyses to identify significantly changed genes and functional pathways in osteoarthritic cartilage. Bone & Joint Research. 7: 343-350. PMID 29922454 DOI: 10.1302/2046-3758.75.Bjr-2017-0284.R1  0.352
2018 Ding M, Li P, Wen Y, Zhao Y, Cheng B, Zhang L, Ma M, Cheng S, Liu L, Du Y, Liang X, He A, Guo X, Zhang F. Integrative analysis of genome-wide association study and brain region related enhancer maps identifies biological pathways for insomnia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29883697 DOI: 10.1016/J.Pnpbp.2018.05.026  0.331
2018 Myers SA, Wright J, Peckner R, Kalish BT, Zhang F, Carr SA. Discovery of proteins associated with a predefined genomic locus via dCas9-APEX-mediated proximity labeling. Nature Methods. PMID 29735997 DOI: 10.1038/S41592-018-0007-1  0.388
2018 Canver MC, Haeussler M, Bauer DE, Orkin SH, Sanjana NE, Shalem O, Yuan GC, Zhang F, Concordet JP, Pinello L. Integrated design, execution, and analysis of arrayed and pooled CRISPR genome-editing experiments. Nature Protocols. 13: 946-986. PMID 29651054 DOI: 10.1038/Nprot.2018.005  0.333
2018 Wang G, Chow RD, Ye L, Guzman CD, Dai X, Dong MB, Zhang F, Sharp PA, Platt RJ, Chen S. Mapping a functional cancer genome atlas of tumor suppressors in mouse liver using AAV-CRISPR-mediated direct in vivo screening. Science Advances. 4: eaao5508. PMID 29503867 DOI: 10.1126/Sciadv.Aao5508  0.322
2018 Fan C, Cai X, Zhang F, Hochstetler C, Chen X, Guo F, Tian W, Zheng Y. Precision Assessment of on- and Off-Target Effects of mTOR Kinase Inhibitors in a Mouse Model Blood. 132: 2632-2632. DOI: 10.1182/Blood-2018-99-115225  0.311
2018 Zhang F, Voytas DF. Modulating gene translational control through genome editing National Science Review. 6: 391-391. DOI: 10.1093/Nsr/Nwy123  0.61
2017 Fan H, Lv P, Huo X, Wu J, Wang Q, Cheng L, Liu Y, Tang Q, Zhang L, Zhang F, Zheng X, Wu H, Wen B. The nuclear matrix protein HNRNPU maintains 3D genome architecture globally in mouse hepatocytes. Genome Research. PMID 29273625 DOI: 10.1101/Gr.224576.117  0.339
2017 He A, Wang W, Prakash NT, Tinkov AA, Skaln AV, Wen Y, Hao J, Guo X, Zhang F. Integrating genome-wide association study summaries and element-gene interaction datasets identified multiple associations between elements and complex diseases. Genetic Epidemiology. PMID 29265413 DOI: 10.1002/Gepi.22106  0.318
2017 Jiang Q, Liu F, Miao C, Li Q, Zhang Z, Xiao P, Su L, Yu K, Chen X, Zhang F, Chakravarti A, Li L. RET somatic mutations are underrecognized in Hirschsprung disease. Genetics in Medicine : Official Journal of the American College of Medical Genetics. PMID 29261189 DOI: 10.1038/Gim.2017.178  0.32
2017 Cox DBT, Gootenberg JS, Abudayyeh OO, Franklin B, Kellner MJ, Joung J, Zhang F. RNA editing with CRISPR-Cas13. Science (New York, N.Y.). PMID 29070703 DOI: 10.1126/Science.Aaq0180  0.31
2017 Zhao Y, He A, Zhu F, Ding M, Hao J, Fan Q, Li P, Liu L, Du Y, Liang X, Guo X, Zhang F, Ma X. Integrating genome-wide association study and expression quantitative trait locus study identifies multiple genes and gene sets associated with schizophrenia. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 29024729 DOI: 10.1016/J.Pnpbp.2017.10.003  0.324
2017 Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Corrigendum: Engineering and optimising deaminase fusions for genome editing. Nature Communications. 8: 16169. PMID 28991237 DOI: 10.1038/Ncomms16169  0.304
2017 Wang W, Huang S, Hou W, Liu Y, Fan Q, He A, Wen Y, Hao J, Guo X, Zhang F. Integrative analysis of GWAS, eQTLs and meQTLs data suggests that multiple gene sets are associated with bone mineral density. Bone & Joint Research. 6: 572-576. PMID 28978616 DOI: 10.1302/2046-3758.610.Bjr-2017-0113.R1  0.367
2017 Abudayyeh OO, Gootenberg JS, Essletzbichler P, Han S, Joung J, Belanto JJ, Verdine V, Cox DBT, Kellner MJ, Regev A, Lander ES, Voytas DF, Ting AY, Zhang F. RNA targeting with CRISPR-Cas13. Nature. PMID 28976959 DOI: 10.1038/Nature24049  0.524
2017 Jain A, Zode G, Kasetti RB, Ran FA, Yan W, Sharma TP, Bugge K, Searby CC, Fingert JH, Zhang F, Clark AF, Sheffield VC. CRISPR-Cas9-based treatment of myocilin-associated glaucoma. Proceedings of the National Academy of Sciences of the United States of America. PMID 28973933 DOI: 10.1073/Pnas.1706193114  0.336
2017 Wang W, Yu Y, Hao J, Wen Y, Han J, Hou W, Liu R, Zhao B, He A, Li P, Fan Q, Wu C, Wang S, Wang X, Ning Y, ... ... Zhang F, et al. Genome-wide DNA methylation profiling of articular cartilage reveals significant epigenetic alterations in Kashin-Beck disease and osteoarthritis. Osteoarthritis and Cartilage. PMID 28818737 DOI: 10.1016/J.Joca.2017.08.002  0.307
2017 Chow RD, Guzman CD, Wang G, Schmidt F, Youngblood MW, Ye L, Errami Y, Dong MB, Martinez MA, Zhang S, Renauer P, Bilguvar K, Gunel M, Sharp PA, Zhang F, et al. AAV-mediated direct in vivo CRISPR screen identifies functional suppressors in glioblastoma. Nature Neuroscience. PMID 28805815 DOI: 10.1038/Nn.4620  0.33
2017 Joung J, Engreitz JM, Konermann S, Abudayyeh OO, Verdine VK, Aguet F, Gootenberg JS, Sanjana NE, Wright JB, Fulco CP, Tseng YY, Yoon CH, Boehm JS, Lander ES, Zhang F. Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood. Nature. PMID 28792927 DOI: 10.1038/Nature23451  0.376
2017 Patel SJ, Sanjana NE, Kishton RJ, Eidizadeh A, Vodnala SK, Cam M, Gartner JJ, Jia L, Steinberg SM, Yamamoto TN, Merchant AS, Mehta GU, Chichura A, Shalem O, Tran E, ... Zhang F, et al. Identification of essential genes for cancer immunotherapy. Nature. PMID 28783722 DOI: 10.1038/Nature23477  0.341
2017 Yamano T, Zetsche B, Ishitani R, Zhang F, Nishimasu H, Nureki O. Structural Basis for the Canonical and Non-canonical PAM Recognition by CRISPR-Cpf1. Molecular Cell. PMID 28781234 DOI: 10.1016/J.Molcel.2017.06.035  0.321
2017 Scott DA, Zhang F. Implications of human genetic variation in CRISPR-based therapeutic genome editing. Nature Medicine. PMID 28759051 DOI: 10.1038/Nm.4377  0.381
2017 Liang X, He A, Wang W, Liu L, Du Y, Fan Q, Li P, Wen Y, Hao J, Guo X, Zhang F. Integrating Genome-Wide Association and eQTLs Studies Identifies the Genes and Gene Sets Associated with Diabetes. Biomed Research International. 2017: 1758636. PMID 28744461 DOI: 10.1155/2017/1758636  0.336
2017 Lu J, Lou H, Fu R, Lu D, Zhang F, Wu Z, Zhang X, Li C, Fang B, Pu F, Wei J, Wei Q, Zhang C, Wang X, Lu Y, et al. Assessing genome-wide copy number variation in the Han Chinese population. Journal of Medical Genetics. PMID 28705883 DOI: 10.1136/Jmedgenet-2017-104613  0.327
2017 Wang X, Zhang Y, Zhang X, Wang D, Jin G, Li B, Xu F, Cheng J, Zhang F, Wu S, Rui S, He J, Zhang R, Liu W. The comprehensive liver transcriptome of two cattle breeds with different intramuscular fat content. Biochemical and Biophysical Research Communications. PMID 28669724 DOI: 10.1016/J.Bbrc.2017.06.157  0.314
2017 Du Y, Wen Y, Guo X, Hao J, Wang W, He A, Fan Q, Li P, Liu L, Liang X, Zhang F. A Genome-wide Expression Association Analysis Identifies Genes and Pathways Associated with Amyotrophic Lateral Sclerosis. Cellular and Molecular Neurobiology. PMID 28639078 DOI: 10.1007/S10571-017-0512-2  0.354
2017 Nishimasu H, Yamano T, Gao L, Zhang F, Ishitani R, Nureki O. Structural Basis for the Altered PAM Recognition by Engineered CRISPR-Cpf1. Molecular Cell. PMID 28595896 DOI: 10.1016/J.Molcel.2017.04.019  0.351
2017 Gao L, Cox DBT, Yan WX, Manteiga JC, Schneider MW, Yamano T, Nishimasu H, Nureki O, Crosetto N, Zhang F. Engineered Cpf1 variants with altered PAM specificities. Nature Biotechnology. PMID 28581492 DOI: 10.1038/Nbt.3900  0.386
2017 Fan Q, Wang W, Hao J, He A, Wen Y, Guo X, Wu C, Ning Y, Wang X, Wang S, Zhang F. Integrating genome-wide association study and expression quantitative trait loci data identifies multiple genes and gene set associated with neuroticism. Progress in Neuro-Psychopharmacology & Biological Psychiatry. PMID 28552732 DOI: 10.1016/J.Pnpbp.2017.05.017  0.364
2017 Tang S, Wang X, Li W, Yang X, Li Z, Liu W, Li C, Zhu Z, Wang L, Wang J, Zhang L, Sun X, Zhi E, Wang H, Li H, ... Zhang F, et al. Biallelic Mutations in CFAP43 and CFAP44 Cause Male Infertility with Multiple Morphological Abnormalities of the Sperm Flagella. American Journal of Human Genetics. PMID 28552195 DOI: 10.1016/J.Ajhg.2017.04.012  0.337
2017 Yan WX, Mirzazadeh R, Garnerone S, Scott D, Schneider MW, Kallas T, Custodio J, Wernersson E, Li Y, Gao L, Federova Y, Zetsche B, Zhang F, Bienko M, Crosetto N. BLISS is a versatile and quantitative method for genome-wide profiling of DNA double-strand breaks. Nature Communications. 8: 15058. PMID 28497783 DOI: 10.1038/Ncomms15058  0.37
2017 Zhang L, Wang J, Zhang C, Li D, Carvalho CM, Ji H, Xiao J, Wu Y, Zhou W, Wang H, Jin L, Luo Y, Wu X, Lupski JR, Zhang F, et al. Efficient CNV breakpoint analysis reveals unexpected structural complexity and correlation of dosage-sensitive genes with clinical severity in genomic disorders. Human Molecular Genetics. PMID 28334874 DOI: 10.1093/Hmg/Ddx102  0.386
2017 Joung J, Konermann S, Gootenberg JS, Abudayyeh OO, Platt RJ, Brigham MD, Sanjana NE, Zhang F. Genome-scale CRISPR-Cas9 knockout and transcriptional activation screening. Nature Protocols. 12: 828-863. PMID 28333914 DOI: 10.1038/Nprot.2017.016  0.311
2017 Yamada M, Watanabe Y, Gootenberg JS, Hirano H, Ran FA, Nakane T, Ishitani R, Zhang F, Nishimasu H, Nureki O. Crystal Structure of the Minimal Cas9 from Campylobacter jejuni Reveals the Molecular Diversity in the CRISPR-Cas9 Systems. Molecular Cell. 65: 1109-1121.e3. PMID 28306506 DOI: 10.1016/J.Molcel.2017.02.007  0.313
2017 Erb MA, Scott TG, Li BE, Xie H, Paulk J, Seo HS, Souza A, Roberts JM, Dastjerdi S, Buckley DL, Sanjana NE, Shalem O, Nabet B, Zeid R, Offei-Addo NK, ... Zhang F, et al. Transcription control by the ENL YEATS domain in acute leukaemia. Nature. PMID 28241139 DOI: 10.1038/Nature21688  0.365
2017 Liu P, Yuan B, Carvalho CM, Wuster A, Walter K, Zhang L, Gambin T, Chong Z, Campbell IM, Coban Akdemir Z, Gelowani V, Writzl K, Bacino CA, Lindsay SJ, Withers M, ... ... Zhang F, et al. An Organismal CNV Mutator Phenotype Restricted to Early Human Development. Cell. 168: 830-842.e7. PMID 28235197 DOI: 10.1016/J.Cell.2017.01.037  0.35
2017 Smargon AA, Cox DB, Pyzocha NK, Zheng K, Slaymaker IM, Gootenberg JS, Abudayyeh OA, Essletzbichler P, Shmakov S, Makarova KS, Koonin EV, Zhang F. Cas13b Is a Type VI-B CRISPR-Associated RNA-Guided RNase Differentially Regulated by Accessory Proteins Csx27 and Csx28. Molecular Cell. PMID 28065598 DOI: 10.1016/J.Molcel.2016.12.023  0.307
2017 Hao J, Wang W, Wen Y, Xiao X, He A, Wu C, Wang S, Guo X, Zhang F. Genome-wide association study identifies COL2A1 locus involved in the hand development failure of Kashin-Beck disease. Scientific Reports. 7: 40020. PMID 28059113 DOI: 10.1038/Srep40020  0.346
2016 Zetsche B, Heidenreich M, Mohanraju P, Fedorova I, Kneppers J, DeGennaro EM, Winblad N, Choudhury SR, Abudayyeh OO, Gootenberg JS, Wu WY, Scott DA, Severinov K, van der Oost J, Zhang F. Multiplex gene editing by CRISPR-Cpf1 using a single crRNA array. Nature Biotechnology. PMID 27918548 DOI: 10.1038/Nbt.3737  0.395
2016 Maji B, Moore CL, Zetsche B, Volz SE, Zhang F, Shoulders MD, Choudhary A. Multidimensional chemical control of CRISPR-Cas9. Nature Chemical Biology. PMID 27820801 DOI: 10.1038/Nchembio.2224  0.369
2016 Yang L, Briggs AW, Chew WL, Mali P, Guell M, Aach J, Goodman DB, Cox D, Kan Y, Lesha E, Soundararajan V, Zhang F, Church G. Engineering and optimising deaminase fusions for genome editing. Nature Communications. 7: 13330. PMID 27804970 DOI: 10.1038/Ncomms13330  0.385
2016 Wu C, Wen Y, Guo X, Yang T, Shen H, Chen X, Tian Q, Tan L, Deng HW, Zhang F. Genetic association, mRNA and protein expression analysis identify ATG4C as a susceptibility gene for Kashin-Beck disease. Osteoarthritis and Cartilage. PMID 27742532 DOI: 10.1016/J.Joca.2016.09.019  0.314
2016 Demorest ZL, Coffman A, Baltes NJ, Stoddard TJ, Clasen BM, Luo S, Retterath A, Yabandith A, Gamo ME, Bissen J, Mathis L, Voytas DF, Zhang F. Direct stacking of sequence-specific nuclease-induced mutations to produce high oleic and low linolenic soybean oil. Bmc Plant Biology. 16: 225. PMID 27733139 DOI: 10.1186/S12870-016-0906-1  0.523
2016 Sanjana NE, Wright J, Zheng K, Shalem O, Fontanillas P, Joung J, Cheng C, Regev A, Zhang F. High-resolution interrogation of functional elements in the noncoding genome. Science (New York, N.Y.). 353: 1545-1549. PMID 27708104 DOI: 10.1126/Science.Aaf7613  0.396
2016 Wang W, Hao J, Zheng S, Fan Q, He A, Wen Y, Guo X, Wu C, Wang S, Yang T, Shen H, Chen X, Tian Q, Tan L, Deng HW, Zhang F, et al. Tissue-specific pathway association analysis using genome-wide association study summaries. Bioinformatics (Oxford, England). PMID 27651483 DOI: 10.1093/Bioinformatics/Btw595  0.31
2016 Shi XW, Shi BH, Lyu AL, Zhang F, Zhou TT, Guo X. Exploring Genome-wide DNA Methylation Profiles Altered in Kashin-Beck Disease Using Infinium Human Methylation 450 Bead Chips. Biomedical and Environmental Sciences : Bes. 29: 539-43. PMID 27554126 DOI: 10.3967/Bes2016.072  0.334
2016 Hao J, Wang W, Wen Y, Xiao X, He A, Guo X, Yang T, Liu X, Shen H, Chen X, Tian Q, Deng HW, Zhang F. A bivariate genome-wide association study identifies ADAM12 as a novel susceptibility gene for Kashin-Beck disease. Scientific Reports. 6: 31792. PMID 27545300 DOI: 10.1038/Srep31792  0.334
2016 Xiao X, Hao J, Wen Y, Wang W, Guo X, Zhang F. Genome-wide association studies and gene expression profiles of rheumatoid arthritis: An analysis. Bone & Joint Research. 5: 314-9. PMID 27445359 DOI: 10.1302/2046-3758.57.2000502  0.317
2016 Chen W, Liu J, Yuan D, Zuo Y, Liu Z, Liu S, Zhu Q, Qiu G, Huang S, Giampietro PF, Zhang F, Wu N, Wu Z. Progress and perspective of TBX6 gene in congenital vertebral malformations. Oncotarget. PMID 27437870 DOI: 10.18632/Oncotarget.10619  0.322
2016 Dong X, Wang X, Zhang F, Tian W. Genome-wide identification of regulatory sequences undergoing accelerated evolution in the human genome. Molecular Biology and Evolution. PMID 27401230 DOI: 10.1093/Molbev/Msw128  0.394
2016 Guan J, Wang D, Cao W, Zhao Y, Du R, Yuan H, Liu Q, Lan L, Zong L, Yang J, Yin Z, Han B, Zhang F, Wang Q. SIX2 haploinsufficiency causes conductive hearing loss with ptosis in humans. Journal of Human Genetics. PMID 27383657 DOI: 10.1038/Jhg.2016.86  0.329
2016 Wang W, Liu Y, Hao J, Zheng S, Wen Y, Xiao X, He A, Fan Q, Zhang F, Liu R. Comparative analysis of gene expression profiles of hip articular cartilage between non-traumatic necrosis and osteoarthritis. Gene. PMID 27374150 DOI: 10.1016/J.Gene.2016.06.058  0.326
2016 Duan Y, Ma G, Huang X, D'Amore PA, Zhang F, Lei H. The CRISPR/Cas9-created MDM2 T309G enhances vitreous-induced expression of MDM2 and proliferation and survival of cells. The Journal of Biological Chemistry. PMID 27246850 DOI: 10.1074/Jbc.M116.729467  0.33
2016 Zhu XB, Lu JQ, Zhi EL, Zhu Y, Zou SS, Zhu ZJ, Zhang F, Li Z. Association of a TDRD1 variant with spermatogenic failure susceptibility in the Han Chinese. Journal of Assisted Reproduction and Genetics. PMID 27233649 DOI: 10.1007/S10815-016-0738-9  0.34
2016 Stoddard TJ, Clasen BM, Baltes NJ, Demorest ZL, Voytas DF, Zhang F, Luo S. Targeted Mutagenesis in Plant Cells through Transformation of Sequence-Specific Nuclease mRNA. Plos One. 11: e0154634. PMID 27176769 DOI: 10.1371/Journal.Pone.0154634  0.647
2016 Liu R, Liu Q, Wang K, Dang X, Zhang F. Comparative analysis of gene expression profiles in normal hip human cartilage and cartilage from patients with necrosis of the femoral head. Arthritis Research & Therapy. 18: 98. PMID 27146865 DOI: 10.1186/S13075-016-0991-4  0.315
2016 Wang L, Xu GL, Gao K, Wilkinson J, Zhang F, Yu L, Liu CY, Yu CF, Wang WB, Li M, Chen W, Fan F, Cong M, Wang JZ. Development of a robust reporter-based assay for the bioactivity determination of anti-VEGF therapeutic antibodies. Journal of Pharmaceutical and Biomedical Analysis. 125: 212-218. PMID 27042807 DOI: 10.1016/j.jpba.2016.03.042  0.463
2016 Hu L, Shang X, Yi S, Cai R, Li Z, Liu C, Liang Y, Cai D, Zhang F, Xu X. Two novel copy number variations involving the α-globin gene cluster on chromosome 16 cause thalassemia in two Chinese families. Molecular Genetics and Genomics : Mgg. PMID 27000657 DOI: 10.1007/S00438-016-1193-0  0.302
2016 Hirano H, Gootenberg JS, Horii T, Abudayyeh OO, Kimura M, Hsu PD, Nakane T, Ishitani R, Hatada I, Zhang F, Nishimasu H, Nureki O. Structure and Engineering of Francisella novicida Cas9. Cell. PMID 26875867 DOI: 10.1016/J.Cell.2016.01.039  0.325
2016 Liu Z, Li X, Zhang JT, Cai YJ, Cheng TL, Cheng C, Wang Y, Zhang CC, Nie YH, Chen ZF, Bian WJ, Zhang L, Xiao J, Lu B, Zhang YF, ... Zhang F, et al. Autism-like behaviours and germline transmission in transgenic monkeys overexpressing MeCP2. Nature. PMID 26808898 DOI: 10.1038/Nature16533  0.302
2016 Tabebordbar M, Zhu K, Cheng J, Widrick J, Yan W, Xiao R, Vandenberghe L, Zhang F, Wagers A. 483. In Vivo DMD Gene Editing in Muscles and Muscle Stem Cells of Dystrophic Mice Molecular Therapy. 24: S191-S192. DOI: 10.1016/S1525-0016(16)33292-0  0.306
2016 Nelson C, Gemberling M, Hakim CH, Ousterout DG, Thakore PI, Castellanos RM, Madhavan S, Pan X, Ran FA, Yan W, Asokan A, Zhang F, Duan D, Gersbach CA. 482. Local and Systemic Gene Editing in a Mouse Model of Duchenne Muscular Dystrophy Molecular Therapy. 24: S191. DOI: 10.1016/S1525-0016(16)33291-9  0.328
2015 Nelson CE, Hakim CH, Ousterout DG, Thakore PI, Moreb EA, Rivera RM, Madhavan S, Pan X, Ran FA, Yan WX, Asokan A, Zhang F, Duan D, Gersbach CA. In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy. Science (New York, N.Y.). PMID 26721684 DOI: 10.1126/Science.Aad5143  0.347
2015 Slaymaker IM, Gao L, Zetsche B, Scott DA, Yan WX, Zhang F. Rationally engineered Cas9 nucleases with improved specificity. Science (New York, N.Y.). PMID 26628643 DOI: 10.1126/Science.Aad5227  0.393
2015 Wen Y, Wang W, Guo X, Zhang F. PAPA: a flexible tool for identifying pleiotropic pathways using genome-wide association study summaries. Bioinformatics (Oxford, England). PMID 26568630 DOI: 10.1093/Bioinformatics/Btv668  0.33
2015 Wen Y, Guo X, Hao J, Xiao X, Wang W, Wu C, Wang S, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW, Zhang F. Integrative analysis of genome-wide association studies and gene expression profiles identified candidate genes for osteoporosis in Kashin-Beck disease patients. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. PMID 26462493 DOI: 10.1007/S00198-015-3364-Y  0.357
2015 Zhao X, Zhao K, Ren J, Zhang F, Jiang C, Hong Y, Jiang K, Yang Q, Wang C, Ding N, Huang L, Zhang Z, Xing Y. An imputation-based genome-wide association study on traits related to male reproduction in a White Duroc × Erhualian F2 population. Animal Science Journal = Nihon Chikusan Gakkaiho. PMID 26425933 DOI: 10.1111/asj.12468  0.476
2015 Zetsche B, Gootenberg JS, Abudayyeh OO, Slaymaker IM, Makarova KS, Essletzbichler P, Volz SE, Joung J, van der Oost J, Regev A, Koonin EV, Zhang F. Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System. Cell. PMID 26422227 DOI: 10.1016/J.Cell.2015.09.038  0.332
2015 Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, Maeda T, ... Zhang F, et al. BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis. Nature. PMID 26375006 DOI: 10.1038/Nature15521  0.369
2015 Nishimasu H, Cong L, Yan WX, Ran FA, Zetsche B, Li Y, Kurabayashi A, Ishitani R, Zhang F, Nureki O. Crystal Structure of Staphylococcus aureus Cas9. Cell. 162: 1113-26. PMID 26317473 DOI: 10.1016/J.Cell.2015.08.007  0.315
2015 Zhang F, Dai L, Lin W, Wang W, Liu X, Zhang J, Yang T, Liu X, Shen H, Chen X, Tan L, Tian Q, Deng HW, Xu X, Guo X. Exome sequencing identified FGF12 as a novel candidate gene for Kashin-Beck disease. Functional & Integrative Genomics. PMID 26290467 DOI: 10.1007/S10142-015-0462-Z  0.403
2015 Parnas O, Jovanovic M, Eisenhaure TM, Herbst RH, Dixit A, Ye CJ, Przybylski D, Platt RJ, Tirosh I, Sanjana NE, Shalem O, Satija R, Raychowdhury R, Mertins P, Carr SA, Zhang F, et al. A Genome-wide CRISPR Screen in Primary Immune Cells to Dissect Regulatory Networks. Cell. PMID 26189680 DOI: 10.1016/J.Cell.2015.06.059  0.324
2015 Wen Y, Hao J, Guo X, Xiao X, Wu C, Wang S, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW, Zhang F. SWGDT: A sliding window-based genotype dependence testing tool for genome-wide susceptibility gene scan. Journal of Biomedical Informatics. PMID 26188273 DOI: 10.1016/J.Jbi.2015.06.025  0.395
2015 Zhang F. CRISPR-Cas9: Prospects and Challenges. Human Gene Therapy. 26: 409-10. PMID 26176430 DOI: 10.1089/Hum.2015.29002.Fzh  0.399
2015 Zhang F, Lupski JR. Non-coding genetic variants in human disease. Human Molecular Genetics. PMID 26152199 DOI: 10.1093/Hmg/Ddv259  0.31
2015 Luo S, Li J, Stoddard TJ, Baltes NJ, Demorest ZL, Clasen BM, Coffman A, Retterath A, Mathis L, Voytas DF, Zhang F. Non-transgenic plant genome editing using purified sequence-specific nucleases. Molecular Plant. PMID 26074033 DOI: 10.1016/J.Molp.2015.05.012  0.63
2015 Xu H, Xiao T, Chen CH, Li W, Meyer CA, Wu Q, Wu D, Cong L, Zhang F, Liu JS, Brown M, Liu XS. Sequence determinants of improved CRISPR sgRNA design. Genome Research. PMID 26063738 DOI: 10.1101/Gr.191452.115  0.368
2015 Ramanan V, Shlomai A, Cox DB, Schwartz RE, Michailidis E, Bhatta A, Scott DA, Zhang F, Rice CM, Bhatia SN. CRISPR/Cas9 cleavage of viral DNA efficiently suppresses hepatitis B virus. Scientific Reports. 5: 10833. PMID 26035283 DOI: 10.1038/Srep10833  0.319
2015 Li J, Stoddard TJ, Demorest ZL, Lavoie PO, Luo S, Clasen BM, Cedrone F, Ray EE, Coffman AP, Daulhac A, Yabandith A, Retterath AJ, Mathis L, Voytas DF, D'Aoust MA, ... Zhang F, et al. Multiplexed, targeted gene editing in Nicotiana benthamiana for glyco-engineering and monoclonal antibody production. Plant Biotechnology Journal. PMID 26011187 DOI: 10.1111/Pbi.12403  0.605
2015 Wang X, Ning Y, Zhang F, Yu F, Tan W, Lei Y, Wu C, Zheng J, Wang S, Yu H, Li Z, Lammi MJ, Guo X. Gene expression signature in endemic osteoarthritis by microarray analysis. International Journal of Molecular Sciences. 16: 11465-81. PMID 25997002 DOI: 10.3390/Ijms160511465  0.338
2015 Izpisua Belmonte JC, Callaway EM, Caddick SJ, Churchland P, Feng G, Homanics GE, Lee KF, Leopold DA, Miller CT, Mitchell JF, Mitalipov S, Moutri AR, Movshon JA, Okano H, Reynolds JH, ... Zhang F, et al. Brains, genes, and primates. Neuron. 86: 617-31. PMID 25950631 DOI: 10.1016/J.Neuron.2015.03.021  0.325
2015 Corrigan-Curay J, O'Reilly M, Kohn DB, Cannon PM, Bao G, Bushman FD, Carroll D, Cathomen T, Joung JK, Roth D, Sadelain M, Scharenberg AM, von Kalle C, Zhang F, Jambou R, et al. Genome editing technologies: defining a path to clinic. Molecular Therapy : the Journal of the American Society of Gene Therapy. 23: 796-806. PMID 25943494 DOI: 10.1038/Mt.2015.54  0.379
2015 English AC, Salerno WJ, Hampton OA, Gonzaga-Jauregui C, Ambreth S, Ritter DI, Beck CR, Davis CF, Dahdouli M, Ma S, Carroll A, Veeraraghavan N, Bruestle J, Drees B, Hastie A, ... ... Zhang F, et al. Assessing structural variation in a personal genome-towards a human reference diploid genome. Bmc Genomics. 16: 286. PMID 25886820 DOI: 10.1186/S12864-015-1479-3  0.357
2015 Shalem O, Sanjana NE, Zhang F. High-throughput functional genomics using CRISPR-Cas9. Nature Reviews. Genetics. 16: 299-311. PMID 25854182 DOI: 10.1038/Nrg3899  0.373
2015 Clasen BM, Stoddard TJ, Luo S, Demorest ZL, Li J, Cedrone F, Tibebu R, Davison S, Ray EE, Daulhac A, Coffman A, Yabandith A, Retterath A, Haun W, Baltes NJ, ... Zhang F, et al. Improving cold storage and processing traits in potato through targeted gene knockout. Plant Biotechnology Journal. PMID 25846201 DOI: 10.1111/Pbi.12370  0.619
2015 Ran FA, Cong L, Yan WX, Scott DA, Gootenberg JS, Kriz AJ, Zetsche B, Shalem O, Wu X, Makarova KS, Koonin EV, Sharp PA, Zhang F. In vivo genome editing using Staphylococcus aureus Cas9. Nature. 520: 186-91. PMID 25830891 DOI: 10.1038/Nature14299  0.395
2015 Chen S, Sanjana NE, Zheng K, Shalem O, Lee K, Shi X, Scott DA, Song J, Pan JQ, Weissleder R, Lee H, Zhang F, Sharp PA. Genome-wide CRISPR screen in a mouse model of tumor growth and metastasis. Cell. 160: 1246-60. PMID 25748654 DOI: 10.1016/J.Cell.2015.02.038  0.34
2015 Cox DB, Platt RJ, Zhang F. Therapeutic genome editing: prospects and challenges. Nature Medicine. 21: 121-31. PMID 25654603 DOI: 10.1038/Nm.3793  0.359
2015 Zhang F, Xiao X, Hao J, Wang S, Wen Y, Guo X. CPAS: a trans-omics pathway analysis tool for jointly analyzing DNA copy number variations and mRNA expression profiles data. Journal of Biomedical Informatics. 53: 363-6. PMID 25546614 DOI: 10.1016/J.Jbi.2014.12.012  0.351
2015 Konermann S, Brigham MD, Trevino AE, Joung J, Abudayyeh OO, Barcena C, Hsu PD, Habib N, Gootenberg JS, Nishimasu H, Nureki O, Zhang F. Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex. Nature. 517: 583-8. PMID 25494202 DOI: 10.1038/Nature14136  0.387
2015 Cong L, Zhang F. Genome engineering using CRISPR-Cas9 system. Methods in Molecular Biology (Clifton, N.J.). 1239: 197-217. PMID 25408407 DOI: 10.1007/978-1-4939-1862-1_10  0.377
2015 Chen L, Zhou W, Zhang C, Lupski JR, Jin L, Zhang F. CNV instability associated with DNA replication dynamics: evidence for replicative mechanisms in CNV mutagenesis. Human Molecular Genetics. 24: 1574-83. PMID 25398944 DOI: 10.1093/Hmg/Ddu572  0.346
2015 Swiech L, Heidenreich M, Banerjee A, Habib N, Li Y, Trombetta J, Sur M, Zhang F. In vivo interrogation of gene function in the mammalian brain using CRISPR-Cas9. Nature Biotechnology. 33: 102-6. PMID 25326897 DOI: 10.1038/Nbt.3055  0.395
2015 Peng Z, Zhou W, Fu W, Du R, Jin L, Zhang F. Correlation between frequency of non-allelic homologous recombination and homology properties: evidence from homology-mediated CNV mutations in the human genome. Human Molecular Genetics. 24: 1225-33. PMID 25324539 DOI: 10.1093/Hmg/Ddu533  0.367
2015 Zhang F, Wen Y, Guo X, Zhang Y, Wang S, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW. Genome-wide pathway-based association study implicates complement system in the development of Kashin-Beck disease in Han Chinese. Bone. 71: 36-41. PMID 25305519 DOI: 10.1016/J.Bone.2014.09.025  0.334
2015 Zhang F, Wen Y, Guo X, Zhang Y, Wang X, Yang T, Shen H, Chen X, Tian Q, Deng HW. Genome-wide association study identifies ITPR2 as a susceptibility gene for Kashin-Beck disease in Han Chinese. Arthritis & Rheumatology (Hoboken, N.J.). 67: 176-81. PMID 25303641 DOI: 10.1002/Art.38898  0.369
2015 Bauer DE, Canver MC, Smith EC, Sher F, Pinello L, Sanjana NE, Shalem O, Chen DD, Schupp PG, Vinjamur DS, Garcia SP, Luc S, Kurita R, Nakamura Y, Fujiwara Y, ... Zhang F, et al. Crispr-Cas9 Saturating Mutagenesis Reveals an Achilles Heel in the BCL11A Erythroid Enhancer for Fetal Hemoglobin Induction (by Genome Editing) Blood. 126: 638-638. DOI: 10.1182/Blood.V126.23.638.638  0.411
2015 Zetsche B, Volz SE, Zhang F. A split-Cas9 architecture for inducible genome editing and transcription modulation Nature Biotechnology. 33: 139-142. DOI: 10.1038/Nbt.3149  0.329
2015 Nelson CE, Moreb DGOJNREA, Castellanos RM, Ran FA, Yan W, Zhang F, Asokan A, Gersbach CA. 397. Correction of the Dystrophin Gene By the CRISPR/Cas9 System in a Mouse Model of Muscular Dystrophy Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34006-0  0.425
2014 Chen L, Zhou W, Zhang L, Zhang F. Genome architecture and its roles in human copy number variation. Genomics & Informatics. 12: 136-44. PMID 25705150 DOI: 10.5808/Gi.2014.12.4.136  0.375
2014 Li W, Xu H, Xiao T, Cong L, Love MI, Zhang F, Irizarry RA, Liu JS, Brown M, Liu XS. MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens. Genome Biology. 15: 554. PMID 25476604 DOI: 10.1186/S13059-014-0554-4  0.384
2014 Trevino AE, Zhang F. Genome editing using cas9 nickases Methods in Enzymology. 546: 161-174. PMID 25398340 DOI: 10.1016/B978-0-12-801185-0.00008-8  0.316
2014 Zhang F, Wen Y, Guo X, Yang T, Shen H, Chen X, Tan L, Tian Q, Deng HW. Trans-omics pathway analysis suggests that eQTLs contribute to chondrocyte apoptosis of Kashin-Beck disease through regulating apoptosis pathway expression. Gene. 553: 166-9. PMID 25307768 DOI: 10.1016/J.Gene.2014.10.018  0.31
2014 Platt RJ, Chen S, Zhou Y, Yim MJ, Swiech L, Kempton HR, Dahlman JE, Parnas O, Eisenhaure TM, Jovanovic M, Graham DB, Jhunjhunwala S, Heidenreich M, Xavier RJ, Langer R, ... Zhang F, et al. CRISPR-Cas9 knockin mice for genome editing and cancer modeling. Cell. 159: 440-55. PMID 25263330 DOI: 10.1016/J.Cell.2014.09.014  0.357
2014 Chen C, Ma H, Zhang F, Chen L, Xing X, Wang S, Zhang X, Luo Y. Screening of Duchenne muscular dystrophy (DMD) mutations and investigating its mutational mechanism in Chinese patients. Plos One. 9: e108038. PMID 25244321 DOI: 10.1371/Journal.Pone.0108038  0.329
2014 Xue W, Chen S, Yin H, Tammela T, Papagiannakopoulos T, Joshi NS, Cai W, Yang G, Bronson R, Crowley DG, Zhang F, Anderson DG, Sharp PA, Jacks T. CRISPR-mediated direct mutation of cancer genes in the mouse liver. Nature. 514: 380-4. PMID 25119044 DOI: 10.1038/Nature13589  0.364
2014 Wagner JC, Platt RJ, Goldfless SJ, Zhang F, Niles JC. Efficient CRISPR-Cas9-mediated genome editing in Plasmodium falciparum. Nature Methods. 11: 915-8. PMID 25108687 DOI: 10.1038/Nmeth.3063  0.358
2014 Sanjana NE, Shalem O, Zhang F. Improved vectors and genome-wide libraries for CRISPR screening. Nature Methods. 11: 783-784. PMID 25075903 DOI: 10.1038/Nmeth.3047  0.332
2014 Wen Y, Zhang F, Li C, He S, Tan W, Lei Y, Zhang Q, Yu H, Zheng J, Guo X. Gene expression analysis suggests bone development-related genes GDF5 and DIO2 are involved in the development of Kashin-Beck disease in children rather than adults. Plos One. 9: e103618. PMID 25072641 DOI: 10.1371/Journal.Pone.0103618  0.375
2014 Hsu PD, Lander ES, Zhang F. Development and applications of CRISPR-Cas9 for genome engineering. Cell. 157: 1262-78. PMID 24906146 DOI: 10.1016/J.Cell.2014.05.010  0.375
2014 Haun W, Coffman A, Clasen BM, Demorest ZL, Lowy A, Ray E, Retterath A, Stoddard T, Juillerat A, Cedrone F, Mathis L, Voytas DF, Zhang F. Improved soybean oil quality by targeted mutagenesis of the fatty acid desaturase 2 gene family. Plant Biotechnology Journal. 12: 934-40. PMID 24851712 DOI: 10.1111/Pbi.12201  0.593
2014 Wu X, Scott DA, Kriz AJ, Chiu AC, Hsu PD, Dadon DB, Cheng AW, Trevino AE, Konermann S, Chen S, Jaenisch R, Zhang F, Sharp PA. Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells. Nature Biotechnology. 32: 670-6. PMID 24752079 DOI: 10.1038/Nbt.2889  0.36
2014 Xiao J, Zhang L, Wang J, Jiang Y, Jin L, Lu J, Jin L, Zhong C, Xu X, Zhang F. Rearrangement structure-independent strategy of CNV breakpoint analysis. Molecular Genetics and Genomics : Mgg. 289: 755-63. PMID 24737421 DOI: 10.1007/S00438-014-0850-4  0.362
2014 Zhang F, Wen Y, Guo X. CRISPR/Cas9 for genome editing: progress, implications and challenges. Human Molecular Genetics. 23: R40-6. PMID 24651067 DOI: 10.1093/Hmg/Ddu125  0.407
2014 Lee MN, Ye C, Villani AC, Raj T, Li W, Eisenhaure TM, Imboywa SH, Chipendo PI, Ran FA, Slowikowski K, Ward LD, Raddassi K, McCabe C, Lee MH, Frohlich IY, ... Zhang F, et al. Common genetic variants modulate pathogen-sensing responses in human dendritic cells. Science (New York, N.Y.). 343: 1246980. PMID 24604203 DOI: 10.1126/Science.1246980  0.301
2014 Pyzocha NK, Ran FA, Hsu PD, Zhang F. RNA-guided genome editing of mammalian cells. Methods in Molecular Biology (Clifton, N.J.). 1114: 269-77. PMID 24557909 DOI: 10.1007/978-1-62703-761-7_17  0.303
2014 Liu P, Gelowani V, Zhang F, Drory VE, Ben-Shachar S, Roney E, Medeiros AC, Moore RJ, DiVincenzo C, Burnette WB, Higgins JJ, Li J, Orr-Urtreger A, Lupski JR. Mechanism, prevalence, and more severe neuropathy phenotype of the Charcot-Marie-Tooth type 1A triplication. American Journal of Human Genetics. 94: 462-9. PMID 24530202 DOI: 10.1016/J.Ajhg.2014.01.017  0.33
2014 Nishimasu H, Ran FA, Hsu PD, Konermann S, Shehata SI, Dohmae N, Ishitani R, Zhang F, Nureki O. Crystal structure of Cas9 in complex with guide RNA and target DNA. Cell. 156: 935-49. PMID 24529477 DOI: 10.1016/J.Cell.2014.02.001  0.316
2014 Chen Y, Guo L, Chen J, Zhao X, Zhou W, Zhang C, Wang J, Jin L, Pei D, Zhang F. Genome-wide CNV analysis in mouse induced pluripotent stem cells reveals dosage effect of pluripotent factors on genome integrity. Bmc Genomics. 15: 79. PMID 24472662 DOI: 10.1186/1471-2164-15-79  0.349
2014 Zhang F, Guo X, Zhang Y, Wen Y, Wang W, Wang S, Yang T, Shen H, Chen X, Tian Q, Tan L, Deng HW. Genome-wide copy number variation study and gene expression analysis identify ABI3BP as a susceptibility gene for Kashin-Beck disease. Human Genetics. 133: 793-9. PMID 24442417 DOI: 10.1007/S00439-014-1418-4  0.373
2014 Klassen TL, Bomben VC, Patel A, Drabek J, Chen TT, Gu W, Zhang F, Chapman K, Lupski JR, Noebels JL, Goldman AM. High-resolution molecular genomic autopsy reveals complex sudden unexpected death in epilepsy risk profile. Epilepsia. 55: e6-12. PMID 24372310 DOI: 10.1111/Epi.12489  0.34
2014 Shalem O, Sanjana NE, Hartenian E, Shi X, Scott DA, Mikkelsen TS, Heckl D, Ebert BL, Root DE, Doench JG, Zhang F. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science (New York, N.Y.). 343: 84-7. PMID 24336571 DOI: 10.1126/Science.1247005  0.392
2014 Wu SX, Wang WZ, Zhang F, Wu CY, Dennis BS, Qu CJ, Bai YD, Guo X. Expression profiles of genes involved in apoptosis and selenium metabolism in articular cartilage of patients with Kashin-Beck osteoarthritis. Gene. 535: 124-30. PMID 24316489 DOI: 10.1016/J.Gene.2013.11.050  0.331
2014 Zhang L, Choi HJ, Estrada K, Leo PJ, Li J, Pei YF, Zhang Y, Lin Y, Shen H, Liu YZ, Liu Y, Zhao Y, Zhang JG, Tian Q, Wang YP, ... Zhang F, et al. Multistage genome-wide association meta-analyses identified two new loci for bone mineral density. Human Molecular Genetics. 23: 1923-33. PMID 24249740 DOI: 10.1093/Hmg/Ddt575  0.3
2014 Qi Y, Starker CG, Zhang F, Baltes NJ, Voytas DF. Tailor-made mutations in Arabidopsis using zinc finger nucleases. Methods in Molecular Biology (Clifton, N.J.). 1062: 193-209. PMID 24057367 DOI: 10.1007/978-1-62703-580-4_10  0.618
2014 Sheffer M, Hu Y, Shalem O, Sanjana N, Dhimolea E, Sarkar S, Bariteau MA, Aftab BT, Groen RWJ, Zhang F, Mitsiades CS. Genome-Scale Crispr-Cas9 Knockout Studies Reveal Mutifactorial and Functionally Overlapping Mechanisms of Myeloma Cell Resistance to Proteasome Inhibition Blood. 124: 273-273. DOI: 10.1182/Blood.V124.21.273.273  0.373
2014 Wu S, Duan C, Zhang F, McKenzie RP, Zheng J, Farooq U, Bai Y, Guo X. Difference in apoptosis-associated genes expression profiling and immunohistology analysis between Kashin-Beck disease and primary osteoarthritis Chinese Science Bulletin. 59: 833-839. DOI: 10.1007/S11434-014-0130-Z  0.312
2013 Ran FA, Hsu PD, Wright J, Agarwala V, Scott DA, Zhang F. Genome engineering using the CRISPR-Cas9 system. Nature Protocols. 8: 2281-308. PMID 24157548 DOI: 10.1038/Nprot.2013.143  0.377
2013 Jia X, Zhang F, Bai J, Gao L, Zhang X, Sun H, Sun D, Guan R, Sun W, Xu L, Yue Z, Yu Y, Fu S. Combinational analysis of linkage and exome sequencing identifies the causative mutation in a Chinese family with congenital cataract. Bmc Medical Genetics. 14: 107. PMID 24103489 DOI: 10.1186/1471-2350-14-107  0.331
2013 Wang J, Yang Y, Guo S, Chen Y, Yang C, Ji H, Song X, Zhang F, Jiang Z, Ma Y, Li Y, Du A, Jin L, Reveille JD, Zou H, et al. Association between copy number variations of HLA-DQA1 and ankylosing spondylitis in the Chinese Han population Genes and Immunity. 14: 500-503. PMID 24048351 DOI: 10.1038/Gene.2013.46  0.301
2013 Zhang F, Liang J, Guo X, Zhang Y, Wen Y, Li Q, Zhang Z, Ma W, Dai L, Liu X, Yang L, Wang J. Exome sequencing and functional analysis identifies a novel mutation in EXT1 gene that causes multiple osteochondromas. Plos One. 8: e72316. PMID 24009674 DOI: 10.1371/Journal.Pone.0072316  0.367
2013 Ran FA, Hsu PD, Lin CY, Gootenberg JS, Konermann S, Trevino AE, Scott DA, Inoue A, Matoba S, Zhang Y, Zhang F. Double nicking by RNA-guided CRISPR Cas9 for enhanced genome editing specificity. Cell. 154: 1380-9. PMID 23992846 DOI: 10.1016/J.Cell.2013.08.021  0.381
2013 Qi Y, Li X, Zhang Y, Starker CG, Baltes NJ, Zhang F, Sander JD, Reyon D, Joung JK, Voytas DF. Targeted deletion and inversion of tandemly arrayed genes in Arabidopsis thaliana using zinc finger nucleases. G3 (Bethesda, Md.). 3: 1707-15. PMID 23979943 DOI: 10.1534/G3.113.006270  0.767
2013 He SL, Tan WH, Zhang ZT, Zhang F, Qu CJ, Lei YX, Zhu YH, Yu HJ, Xiang YZ, Guo X. Mitochondrial-related gene expression profiles suggest an important role of PGC-1alpha in the compensatory mechanism of endemic dilated cardiomyopathy. Experimental Cell Research. 319: 2604-16. PMID 23954821 DOI: 10.1016/J.Yexcr.2013.07.018  0.315
2013 Konermann S, Brigham MD, Trevino AE, Hsu PD, Heidenreich M, Cong L, Platt RJ, Scott DA, Church GM, Zhang F. Optical control of mammalian endogenous transcription and epigenetic states. Nature. 500: 472-6. PMID 23877069 DOI: 10.1038/Nature12466  0.383
2013 Hsu PD, Scott DA, Weinstein JA, Ran FA, Konermann S, Agarwala V, Li Y, Fine EJ, Wu X, Shalem O, Cradick TJ, Marraffini LA, Bao G, Zhang F. DNA targeting specificity of RNA-guided Cas9 nucleases. Nature Biotechnology. 31: 827-32. PMID 23873081 DOI: 10.1038/Nbt.2647  0.363
2013 Bikard D, Jiang W, Samai P, Hochschild A, Zhang F, Marraffini LA. Programmable repression and activation of bacterial gene expression using an engineered CRISPR-Cas system. Nucleic Acids Research. 41: 7429-37. PMID 23761437 DOI: 10.1093/Nar/Gkt520  0.349
2013 Wang X, Wang S, He SL, Zhang F, Tan WH, Lei YX, Yu HJ, Li Z, Ning YJ, Xiang YZ, Guo X. Comparing gene expression profiles of Kashin-Beck and Keshan diseases occurring within the same endemic areas of China Science China Life Sciences. 56: 797-803. PMID 23729183 DOI: 10.1007/S11427-013-4495-Z  0.301
2013 Wang H, Yang H, Shivalila CS, Dawlaty MM, Cheng AW, Zhang F, Jaenisch R. One-step generation of mice carrying mutations in multiple genes by CRISPR/Cas-mediated genome engineering. Cell. 153: 910-8. PMID 23643243 DOI: 10.1016/J.Cell.2013.04.025  0.37
2013 Beurdeley M, Bietz F, Li J, Thomas S, Stoddard T, Juillerat A, Zhang F, Voytas DF, Duchateau P, Silva GH. Compact designer TALENs for efficient genome engineering. Nature Communications. 4: 1762. PMID 23612303 DOI: 10.1038/Ncomms2782  0.61
2013 Zhao Y, Han Y, Zhang L, Wang Y, Ma Y, Zhang F, Fu D, Wang X. Quantitative assessment of the effect of cytochrome P450 2C9 gene polymorphism and colorectal cancer. Plos One. 8: e60607. PMID 23577132 DOI: 10.1371/Journal.Pone.0060607  0.301
2013 Zhou W, Zhang F, Chen X, Shen Y, Lupski JR, Jin L. Increased genome instability in human DNA segments with self-chains: homology-induced structural variations via replicative mechanisms. Human Molecular Genetics. 22: 2642-51. PMID 23474816 DOI: 10.1093/Hmg/Ddt113  0.385
2013 Chen X, Shen Y, Zhang F, Chiang C, Pillalamarri V, Blumenthal I, Talkowski M, Wu BL, Gusella JF. Molecular analysis of a deletion hotspot in the NRXN1 region reveals the involvement of short inverted repeats in deletion CNVs. American Journal of Human Genetics. 92: 375-86. PMID 23472757 DOI: 10.1016/J.Ajhg.2013.02.006  0.348
2013 Jiang W, Bikard D, Cox D, Zhang F, Marraffini LA. RNA-guided editing of bacterial genomes using CRISPR-Cas systems. Nature Biotechnology. 31: 233-9. PMID 23360965 DOI: 10.1038/Nbt.2508  0.38
2013 Cong L, Ran FA, Cox D, Lin S, Barretto R, Habib N, Hsu PD, Wu X, Jiang W, Marraffini LA, Zhang F. Multiplex genome engineering using CRISPR/Cas systems. Science (New York, N.Y.). 339: 819-23. PMID 23287718 DOI: 10.1126/Science.1231143  0.363
2013 Qi Y, Zhang Y, Zhang F, Baller JA, Cleland SC, Ryu Y, Starker CG, Voytas DF. Increasing frequencies of site-specific mutagenesis and gene targeting in Arabidopsis by manipulating DNA repair pathways. Genome Research. 23: 547-54. PMID 23282329 DOI: 10.1101/Gr.145557.112  0.634
2013 Ding Q, Lee YK, Schaefer EA, Peters DT, Veres A, Kim K, Kuperwasser N, Motola DL, Meissner TB, Hendriks WT, Trevisan M, Gupta RM, Moisan A, Banks E, Friesen M, ... Zhang F, et al. A TALEN genome-editing system for generating human stem cell-based disease models. Cell Stem Cell. 12: 238-51. PMID 23246482 DOI: 10.1016/J.Stem.2012.11.011  0.345
2013 Sun Z, Liu P, Jia X, Withers MA, Jin L, Lupski JR, Zhang F. Replicative mechanisms of CNV formation preferentially occur as intrachromosomal events: evidence from Potocki-Lupski duplication syndrome. Human Molecular Genetics. 22: 749-56. PMID 23161748 DOI: 10.1093/Hmg/Dds482  0.344
2013 Zhang F, Guo X, Duan C, Wu S, Yu H, Lammi M. Identification of differentially expressed genes and pathways between primary osteoarthritis and endemic osteoarthritis (Kashin-Beck disease). Scandinavian Journal of Rheumatology. 42: 71-9. PMID 23157206 DOI: 10.3109/03009742.2012.698303  0.317
2013 Zhang Y, Zhang F, Li X, Baller JA, Qi Y, Starker CG, Bogdanove AJ, Voytas DF. Transcription activator-like effector nucleases enable efficient plant genome engineering. Plant Physiology. 161: 20-7. PMID 23124327 DOI: 10.1104/Pp.112.205179  0.661
2013 Wang S, Duan C, Zhang F, Ma W, Guo X. Regulatory gene networks and signaling pathways from primary osteoarthritis and Kashin-Beck disease, an endemic osteoarthritis, identified by three analysis software. Gene. 512: 89-96. PMID 23069848 DOI: 10.1016/J.Gene.2012.10.006  0.304
2012 Zhang F, Guo X, Wu S, Han J, Liu Y, Shen H, Deng HW. Genome-wide pathway association studies of multiple correlated quantitative phenotypes using principle component analyses. Plos One. 7: e53320. PMID 23285279 DOI: 10.1371/Journal.Pone.0053320  0.338
2012 Zhang YP, Deng FY, Yang TL, Zhang F, Chen XD, Shen H, Zhu XZ, Tian Q, Deng HW. Genome-wide association study identified CNP12587 region underlying height variation in Chinese females. Plos One. 7: e44292. PMID 22957059 DOI: 10.1371/Journal.Pone.0044292  0.36
2012 Hsu PD, Zhang F. Dissecting neural function using targeted genome engineering technologies. Acs Chemical Neuroscience. 3: 603-610. PMID 22896804 DOI: 10.1021/Cn300089K  0.352
2012 Cong L, Zhou R, Kuo YC, Cunniff M, Zhang F. Comprehensive interrogation of natural TALE DNA-binding modules and transcriptional repressor domains. Nature Communications. 3: 968. PMID 22828628 DOI: 10.1038/Ncomms1962  0.35
2012 Zhang F, Guo X, Wang W, Wu S, Ma W, Yan H. Expression profile analysis of mycotoxin-related genes in cartilage with endemic osteochondropathy Kashin-Beck Disease. Bmc Musculoskeletal Disorders. 13: 130. PMID 22828367 DOI: 10.1186/1471-2474-13-130  0.352
2012 Briggs AW, Rios X, Chari R, Yang L, Zhang F, Mali P, Church GM. Iterative capped assembly: rapid and scalable synthesis of repeat-module DNA such as TAL effectors from individual monomers. Nucleic Acids Research. 40: e117. PMID 22740649 DOI: 10.1093/Nar/Gks624  0.323
2012 Ning Y, Zhang F, Zhu Y, Chen H, Lu J, Li Z. Novel androgen receptor gene mutation in patient with complete androgen insensitivity syndrome. Urology. 80: 216-218. PMID 22608796 DOI: 10.1016/J.Urology.2012.03.028  0.302
2012 Jiang Y, Zhang Y, Zhang P, Sang T, Zhang F, Ji T, Huang Q, Xie H, Du R, Cai B, Zhao H, Wang J, Wu Y, Wu H, Xu K, et al. NIPA2 located in 15q11.2 is mutated in patients with childhood absence epilepsy. Human Genetics. 131: 1217-24. PMID 22367439 DOI: 10.1007/S00439-012-1149-3  0.321
2012 Sanjana NE, Cong L, Zhou Y, Cunniff MM, Feng G, Zhang F. A transcription activator-like effector toolbox for genome engineering. Nature Protocols. 7: 171-92. PMID 22222791 DOI: 10.1038/Nprot.2011.431  0.365
2011 Zhang F, Vierock J, Yizhar O, Fenno LE, Tsunoda S, Kianianmomeni A, Prigge M, Berndt A, Cushman J, Polle J, Magnuson J, Hegemann P, Deisseroth K. The microbial opsin family of optogenetic tools. Cell. 147: 1446-57. PMID 22196724 DOI: 10.1016/J.Cell.2011.12.004  0.301
2011 Liu P, Lacaria M, Zhang F, Withers M, Hastings PJ, Lupski JR. Frequency of nonallelic homologous recombination is correlated with length of homology: evidence that ectopic synapsis precedes ectopic crossing-over. American Journal of Human Genetics. 89: 580-8. PMID 21981782 DOI: 10.1016/J.Ajhg.2011.09.009  0.365
2011 Liu P, Erez A, Nagamani SC, Dhar SU, Kołodziejska KE, Dharmadhikari AV, Cooper ML, Wiszniewska J, Zhang F, Withers MA, Bacino CA, Campos-Acevedo LD, Delgado MR, Freedenberg D, Garnica A, et al. Chromosome catastrophes involve replication mechanisms generating complex genomic rearrangements. Cell. 146: 889-903. PMID 21925314 DOI: 10.1016/J.Cell.2011.07.042  0.349
2011 Lu C, Zhang F, Yang H, Xu M, Du G, Wu W, An Y, Qin Y, Ji G, Han X, Gu A, Xia Y, Song L, Wang S, Jin L, et al. Additional genomic duplications in AZFc underlie the b2/b3 deletion-associated risk of spermatogenic impairment in Han Chinese population. Human Molecular Genetics. 20: 4411-21. PMID 21852246 DOI: 10.1093/Hmg/Ddr369  0.327
2011 Hancock CN, Zhang F, Floyd K, Richardson AO, Lafayette P, Tucker D, Wessler SR, Parrott WA. The rice miniature inverted repeat transposable element mPing is an effective insertional mutagen in soybean. Plant Physiology. 157: 552-62. PMID 21844309 DOI: 10.1104/Pp.111.181206  0.777
2011 Zhang F, Guo X, Wang W, Yan H, Li C. Genome-wide gene expression analysis suggests an important role of hypoxia in the pathogenesis of endemic osteochondropathy Kashin-Beck disease. Plos One. 6: e22983. PMID 21829570 DOI: 10.1371/Journal.Pone.0022983  0.368
2011 Zhu H, Shang D, Sun M, Choi S, Liu Q, Hao J, Figuera LE, Zhang F, Choy KW, Ao Y, Liu Y, Zhang XL, Yue F, Wang MR, Jin L, et al. X-linked congenital hypertrichosis syndrome is associated with interchromosomal insertions mediated by a human-specific palindrome near SOX3. American Journal of Human Genetics. 88: 819-26. PMID 21636067 DOI: 10.1016/J.Ajhg.2011.05.004  0.334
2011 Curtin SJ, Zhang F, Sander JD, Haun WJ, Starker C, Baltes NJ, Reyon D, Dahlborg EJ, Goodwin MJ, Coffman AP, Dobbs D, Joung JK, Voytas DF, Stupar RM. Targeted mutagenesis of duplicated genes in soybean with zinc-finger nucleases. Plant Physiology. 156: 466-73. PMID 21464476 DOI: 10.1104/Pp.111.172981  0.774
2011 Yizhar O, Fenno L, Zhang F, Hegemann P, Diesseroth K. Microbial opsins: a family of single-component tools for optical control of neural activity. Cold Spring Harbor Protocols. 2011: top102. PMID 21363959 DOI: 10.1101/Pdb.Top102  0.301
2011 Zhang F, Guo X, Deng H. Multilocus association testing of quantitative traits based on partial least-squares analysis. Plos One. 6. PMID 21304821 DOI: 10.1371/Journal.Pone.0016739  0.335
2011 Reyon D, Kirkpatrick JR, Sander JD, Zhang F, Voytas DF, Joung JK, Dobbs D, Coffman CR. ZFNGenome: a comprehensive resource for locating zinc finger nuclease target sites in model organisms. Bmc Genomics. 12: 83. PMID 21276248 DOI: 10.1186/1471-2164-12-83  0.76
2011 Zhang F, Cong L, Lodato S, Kosuri S, Church GM, Arlotta P. Efficient construction of sequence-specific TAL effectors for modulating mammalian transcription. Nature Biotechnology. 29: 149-53. PMID 21248753 DOI: 10.1038/Nbt.1775  0.339
2011 Carvalho CM, Zhang F, Lupski JR. Structural variation of the human genome: mechanisms, assays, and role in male infertility. Systems Biology in Reproductive Medicine. 57: 3-16. PMID 21210740 DOI: 10.3109/19396368.2010.527427  0.344
2011 Zhang F, Voytas DF. Targeted mutagenesis in Arabidopsis using zinc-finger nucleases. Methods in Molecular Biology (Clifton, N.J.). 701: 167-77. PMID 21181530 DOI: 10.1007/978-1-61737-957-4_9  0.629
2011 Sander JD, Dahlborg EJ, Goodwin MJ, Cade L, Zhang F, Cifuentes D, Curtin SJ, Blackburn JS, Thibodeau-Beganny S, Qi Y, Pierick CJ, Hoffman E, Maeder ML, Khayter C, Reyon D, et al. Selection-free zinc-finger-nuclease engineering by context-dependent assembly (CoDA). Nature Methods. 8: 67-9. PMID 21151135 DOI: 10.1038/Nmeth.1542  0.754
2010 Tan L, Liu R, Lei S, Pan R, Yang T, Yan H, Pei Y, Yang F, Zhang F, Pan F, Zhang Y, Hu H, Levy S, Deng H. A genome-wide association analysis implicates SOX6 as a candidate gene for wrist bone mass. Science China. Life Sciences. 53: 1065-72. PMID 21104366 DOI: 10.1007/S11427-010-4056-7  0.303
2010 Fu W, Zhang F, Wang Y, Gu X, Jin L. Identification of copy number variation hotspots in human populations. American Journal of Human Genetics. 87: 494-504. PMID 20920665 DOI: 10.1016/J.Ajhg.2010.09.006  0.367
2010 Hoshaw JP, Unger-Wallace E, Zhang F, Voytas DF. A transient assay for monitoring zinc finger nuclease activity at endogenous plant gene targets. Methods in Molecular Biology (Clifton, N.J.). 649: 299-313. PMID 20680843 DOI: 10.1007/978-1-60761-753-2_19  0.641
2010 Christian M, Cermak T, Doyle EL, Schmidt C, Zhang F, Hummel A, Bogdanove AJ, Voytas DF. Targeting DNA double-strand breaks with TAL effector nucleases. Genetics. 186: 757-61. PMID 20660643 DOI: 10.1534/Genetics.110.120717  0.586
2010 Gonzaga-Jauregui C, Zhang F, Towne CF, Batish SD, Lupski JR. GJB1/Connexin 32 whole gene deletions in patients with X-linked Charcot-Marie-Tooth disease. Neurogenetics. 11: 465-70. PMID 20532933 DOI: 10.1007/S10048-010-0247-4  0.364
2010 Zhang F, Maeder ML, Unger-Wallace E, Hoshaw JP, Reyon D, Christian M, Li X, Pierick CJ, Dobbs D, Peterson T, Joung JK, Voytas DF. High frequency targeted mutagenesis in Arabidopsis thaliana using zinc finger nucleases. Proceedings of the National Academy of Sciences of the United States of America. 107: 12028-33. PMID 20508152 DOI: 10.1073/Pnas.0914991107  0.714
2010 Zhang F, Seeman P, Liu P, Weterman MA, Gonzaga-Jauregui C, Towne CF, Batish SD, De Vriendt E, De Jonghe P, Rautenstrauss B, Krause KH, Khajavi M, Posadka J, Vandenberghe A, Palau F, et al. Mechanisms for nonrecurrent genomic rearrangements associated with CMT1A or HNPP: rare CNVs as a cause for missing heritability. American Journal of Human Genetics. 86: 892-903. PMID 20493460 DOI: 10.1016/J.Ajhg.2010.05.001  0.408
2010 Hancock CN, Zhang F, Wessler SR. Transposition of the Tourist-MITE mPing in yeast: an assay that retains key features of catalysis by the class 2 PIF/Harbinger superfamily. Mobile Dna. 1: 5. PMID 20226077 DOI: 10.1186/1759-8753-1-5  0.625
2010 Lupski JR, Reid JG, Gonzaga-Jauregui C, Rio Deiros D, Chen DC, Nazareth L, Bainbridge M, Dinh H, Jing C, Wheeler DA, McGuire AL, Zhang F, Stankiewicz P, Halperin JJ, Yang C, et al. Whole-genome sequencing in a patient with Charcot-Marie-Tooth neuropathy. The New England Journal of Medicine. 362: 1181-91. PMID 20220177 DOI: 10.1056/Nejmoa0908094  0.38
2010 Zhang L, Guo YF, Liu YZ, Liu YJ, Xiong DH, Liu XG, Wang L, Yang TL, Lei SF, Guo Y, Yan H, Pei YF, Zhang F, Papasian CJ, Recker RR, et al. Pathway-based genome-wide association analysis identified the importance of regulation-of-autophagy pathway for ultradistal radius BMD. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 25: 1572-80. PMID 20200951 DOI: 10.1002/Jbmr.36  0.341
2010 Zhang F, Potocki L, Sampson JB, Liu P, Sanchez-Valle A, Robbins-Furman P, Navarro AD, Wheeler PG, Spence JE, Brasington CK, Withers MA, Lupski JR. Identification of uncommon recurrent Potocki-Lupski syndrome-associated duplications and the distribution of rearrangement types and mechanisms in PTLS. American Journal of Human Genetics. 86: 462-70. PMID 20188345 DOI: 10.1016/J.Ajhg.2010.02.001  0.387
2010 Carvalho CM, Zhang F, Lupski JR. Evolution in health and medicine Sackler colloquium: Genomic disorders: a window into human gene and genome evolution. Proceedings of the National Academy of Sciences of the United States of America. 107: 1765-71. PMID 20080665 DOI: 10.1073/Pnas.0906222107  0.387
2010 Guo Y, Tan LJ, Lei SF, Yang TL, Chen XD, Zhang F, Chen Y, Pan F, Yan H, Liu X, Tian Q, Zhang ZX, Zhou Q, Qiu C, Dong SS, et al. Genome-wide association study identifies ALDH7A1 as a novel susceptibility gene for osteoporosis. Plos Genetics. 6: e1000806. PMID 20072603 DOI: 10.1371/Journal.Pgen.1000806  0.335
2009 Naito K, Zhang F, Tsukiyama T, Saito H, Hancock CN, Richardson AO, Okumoto Y, Tanisaka T, Wessler SR. Unexpected consequences of a sudden and massive transposon amplification on rice gene expression. Nature. 461: 1130-4. PMID 19847266 DOI: 10.1038/Nature08479  0.787
2009 Zhang F, Gu W, Hurles ME, Lupski JR. Copy number variation in human health, disease, and evolution. Annual Review of Genomics and Human Genetics. 10: 451-481. PMID 19715442 DOI: 10.1146/Annurev.Genom.9.081307.164217  0.411
2009 Nagamani SC, Zhang F, Shchelochkov OA, Bi W, Ou Z, Scaglia F, Probst FJ, Shinawi M, Eng C, Hunter JV, Sparagana S, Lagoe E, Fong CT, Pearson M, Doco-Fenzy M, et al. Microdeletions including YWHAE in the Miller-Dieker syndrome region on chromosome 17p13.3 result in facial dysmorphisms, growth restriction, and cognitive impairment. Journal of Medical Genetics. 46: 825-33. PMID 19584063 DOI: 10.1136/Jmg.2009.067637  0.349
2009 Zhang F, Carvalho CMB, Lupski JR. Complex human chromosomal and genomic rearrangements Trends in Genetics. 25: 298-307. PMID 19560228 DOI: 10.1016/J.Tig.2009.05.005  0.355
2009 Zhang F, Khajavi M, Connolly AM, Towne CF, Batish SD, Lupski JR. The DNA replication FoSTeS/MMBIR mechanism can generate genomic, genic and exonic complex rearrangements in humans. Nature Genetics. 41: 849-53. PMID 19543269 DOI: 10.1038/Ng.399  0.395
2009 Carvalho CM, Zhang F, Liu P, Patel A, Sahoo T, Bacino CA, Shaw C, Peacock S, Pursley A, Tavyev YJ, Ramocki MB, Nawara M, Obersztyn E, Vianna-Morgante AM, Stankiewicz P, et al. Complex rearrangements in patients with duplications of MECP2 can occur by fork stalling and template switching. Human Molecular Genetics. 18: 2188-203. PMID 19324899 DOI: 10.1093/Hmg/Ddp151  0.389
2009 Bi W, Sapir T, Shchelochkov OA, Zhang F, Withers MA, Hunter JV, Levy T, Shinder V, Peiffer DA, Gunderson KL, Nezarati MM, Shotts VA, Amato SS, Savage SK, Harris DJ, et al. Increased LIS1 expression affects human and mouse brain development. Nature Genetics. 41: 168-77. PMID 19136950 DOI: 10.1038/Ng.302  0.323
2009 Yan J, Zhang F, Brundage E, Scheuerle A, Lanpher B, Erickson RP, Powis Z, Robinson HB, Trapane PL, Stachiw-Hietpas D, Keppler-Noreuil KM, Lalani SR, Sahoo T, Chinault AC, Patel A, et al. Genomic duplication resulting in increased copy number of genes encoding the sister chromatid cohesion complex conveys clinical consequences distinct from Cornelia de Lange. Journal of Medical Genetics. 46: 626-34. PMID 19052029 DOI: 10.1136/Jmg.2008.062471  0.41
2008 Gu W, Zhang F, Lupski JR. Mechanisms for human genomic rearrangements Pathogenetics. 1: 4-4. PMID 19014668 DOI: 10.1186/1755-8417-1-4  0.373
2008 Doco-Fenzy M, Holder-Espinasse M, Bieth E, Magdelaine C, Vincent M, Khoury M, Andrieux J, Zhang F, Lupski JR, Klink R, Schneider A, Goze-Martineau O, Cuisset J, Vallee L, Manouvrier-Hanu S, et al. The clinical spectrum associated with a chromosome 17 short arm proximal duplication (dup 17p11.2) in three patients. American Journal of Medical Genetics Part A. 146: 917-924. PMID 18327785 DOI: 10.1002/Ajmg.A.32195  0.317
2008 Zhang F, Xiao P, Yang F, Shen H, Xiong DH, Deng HY, Papasian CJ, Drees BM, Hamilton JJ, Recker RR, Deng HW. A whole genome linkage scan for QTLs underlying peak bone mineral density. Osteoporosis International. 19: 303-310. PMID 17882466 DOI: 10.1007/S00198-007-0468-Z  0.313
2007 He LN, Xiong DH, Liu YJ, Zhang F, Recker RR, Deng HW. Association study of the oestrogen signalling pathway genes in relation to age at natural menopause. Journal of Genetics. 86: 269-276. PMID 18305346 DOI: 10.1007/S12041-007-0034-7  0.313
2007 Yang G, Zhang F, Hancock CN, Wessler SR. Transposition of the rice miniature inverted repeat transposable element mPing in Arabidopsis thaliana. Proceedings of the National Academy of Sciences of the United States of America. 104: 10962-7. PMID 17578919 DOI: 10.1073/Pnas.0702080104  0.738
2007 Chen Y, Xiong DH, Yang TL, Yang F, Jiang H, Zhang F, Shen H, Xiao P, Recker RR, Deng HW. Variations in RANK gene are associated with adult height in Caucasians. American Journal of Human Biology : the Official Journal of the Human Biology Council. 19: 559-65. PMID 17546619 DOI: 10.1002/Ajhb.20619  0.308
2006 Zhang J, Zhang F, Peterson T. Transposition of reversed Ac element ends generates novel chimeric genes in maize. Plos Genetics. 2: e164. PMID 17029561 DOI: 10.1371/Journal.Pgen.0020164  0.605
2006 Zhang F, Peterson T. Gene conversion between direct noncoding repeats promotes genetic and phenotypic diversity at a regulatory locus of Zea mays (L.). Genetics. 174: 753-62. PMID 16816430 DOI: 10.1534/Genetics.105.053942  0.614
2006 Zhang F, Li Z, Wen B, Jiang J, Shao M, Zhao Y, He Y, Song X, Qian J, Lu D, Jin L. A frequent partial AZFc deletion does not render an increased risk of spermatogenic impairment in East Asians. Annals of Human Genetics. 70: 304-13. PMID 16674553 DOI: 10.1111/J.1529-8817.2005.00231.X  0.32
2005 Zhang F, Peterson T. Comparisons of maize pericarp color1 alleles reveal paralogous gene recombination and an organ-specific enhancer region. The Plant Cell. 17: 903-14. PMID 15722466 DOI: 10.1105/Tpc.104.029660  0.562
2005 Yu J, Wang J, Lin W, Li S, Li H, Zhou J, Ni P, Dong W, Hu S, Zeng C, Zhang J, Zhang Y, Li R, Xu Z, Li S, ... ... Zhang F, et al. The Genomes of Oryza sativa: a history of duplications. Plos Biology. 3: e38. PMID 15685292 DOI: 10.1371/Journal.Pbio.0030038  0.719
2003 Qin E, Zhu Q, Yu M, Fan B, Chang G, Si B, Yang B, Peng W, Jiang T, Liu B, Deng Y, Liu H, Zhang Y, Wang C, Li Y, ... ... Zhang F, et al. A complete sequence and comparative analysis of a SARS-associated virus (Isolate BJ01). Chinese Science Bulletin = Kexue Tongbao. 48: 941-948. PMID 32214698 DOI: 10.1007/Bf03184203  0.675
2003 Bi S, Qin E, Xu Z, Li W, Wang J, Hu Y, Liu Y, Duan S, Hu J, Han Y, Xu J, Li Y, Yi Y, Zhou Y, Lin W, ... ... Zhang F, et al. Complete genome sequences of the SARS-CoV: the BJ Group (Isolates BJ01-BJ04). Genomics, Proteomics & Bioinformatics. 1: 180-92. PMID 15629030 DOI: 10.1016/S1672-0229(03)01023-4  0.638
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