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William D. Hardie, M.D. - Publications

Affiliations: 
Cincinnati Children's Hospital and Medical Center, USA 
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43 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Yombo DJK, Madala SK, Vemulapalli CP, Ediga HH, Hardie WD. Pulmonary fibroelastosis - A review. Matrix Biology : Journal of the International Society For Matrix Biology. 124: 1-7. PMID 37922998 DOI: 10.1016/j.matbio.2023.10.003  0.382
2019 Guo J, Hardie WD, Cleveland ZI, Davidson CR, Xu X, Madala SK, Woods JC. Longitudinal free-breathing MRI measurement of murine lung physiology in a progressive model of lung fibrosis. Journal of Applied Physiology (Bethesda, Md. : 1985). PMID 30730810 DOI: 10.1152/japplphysiol.00993.2018  0.4
2018 Kramer EL, Hardie WD, Madala SK, Davidson CR, Clancy JP. Subacute TGFβ Expression Drives Inflammation, Goblet Cell Hyperplasia, and Pulmonary Function Abnormalities in Mice with Effects Dependent on CFTR Function. American Journal of Physiology. Lung Cellular and Molecular Physiology. PMID 29877096 DOI: 10.1152/Ajplung.00530.2017  0.47
2018 Kramer EL, Hardie W, Hudock K, Davidson C, Ostmann A, Clancy JP. 2045 The role of TGFβ in driving early cystic fibrosis lung disease Journal of Clinical and Translational Science. 2: 33-33. DOI: 10.1017/cts.2018.139  0.383
2017 Cleveland ZI, Zhou YM, Akinyi TG, Dunn RS, Davidson CR, Guo J, Woods JC, Hardie WD. Magnetic Resonance Imaging of Disease Progression and Resolution in a Transgenic Mouse Model of Pulmonary Fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00458.2016. PMID 28130263 DOI: 10.1152/Ajplung.00458.2016  0.436
2016 Madala SK, Sontake V, Edukulla R, Davidson CR, Schmidt S, Hardie WD. Unique and Redundant Functions of P70S6K Isoforms Regulate Mesenchymal Cell Proliferation and Migration in Pulmonary Fibrosis. American Journal of Respiratory Cell and Molecular Biology. PMID 27438654 DOI: 10.1165/Rcmb.2016-0090Oc  0.504
2016 Glasser SW, Hagood JS, Wong S, Taype CA, Madala SK, Hardie WD. Mechanisms of Lung Fibrosis Resolution. The American Journal of Pathology. PMID 27021937 DOI: 10.1016/J.Ajpath.2016.01.018  0.451
2015 Madala SK, Thomas G, Edukulla R, Davidson C, Schmidt S, Schehr A, Hardie WD. The p70 Ribosomal S6 Kinase Regulates Subpleural Fibrosis Following Transforming Growth Factor-α Expression in the Lung. American Journal of Physiology. Lung Cellular and Molecular Physiology. ajplung.00063.2015. PMID 26566903 DOI: 10.1152/Ajplung.00063.2015  0.489
2015 Sontake V, Shanmukhappa SK, DiPasquale BA, Reddy GB, Medvedovic M, Hardie WD, White ES, Madala SK. Fibrocytes Regulate Wilms Tumor 1-Positive Cell Accumulation in Severe Fibrotic Lung Disease. Journal of Immunology (Baltimore, Md. : 1950). 195: 3978-91. PMID 26371248 DOI: 10.4049/Jimmunol.1500963  0.49
2014 Madala SK, Korfhagen TR, Schmidt S, Davidson C, Edukulla R, Ikegami M, Violette SM, Weinreb PH, Sheppard D, Hardie WD. Inhibition of the αvβ6 integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 306: L726-35. PMID 24508732 DOI: 10.1152/Ajplung.00357.2013  0.452
2014 Madala SK, Edukulla R, Phatak M, Schmidt S, Davidson C, Acciani TH, Korfhagen TR, Medvedovic M, Lecras TD, Wagner K, Hardie WD. Dual targeting of MEK and PI3K pathways attenuates established and progressive pulmonary fibrosis. Plos One. 9: e86536. PMID 24475138 DOI: 10.1371/Journal.Pone.0086536  0.485
2014 Madala SK, Edukulla R, Schmidt S, Davidson C, Ikegami M, Hardie WD. Bone marrow-derived stromal cells are invasive and hyperproliferative and alter transforming growth factor-α-induced pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 50: 777-86. PMID 24199692 DOI: 10.1165/rcmb.2013-0042OC  0.41
2013 Yuan Y, Yeh LK, Liu H, Yamanaka O, Hardie WD, Kao WW, Liu CY. Targeted overexpression of TGF-α in the corneal epithelium of adult transgenic mice induces changes in anterior segment morphology and activates noncanonical Wnt signaling. Investigative Ophthalmology & Visual Science. 54: 1829-37. PMID 23412089 DOI: 10.1167/Iovs.12-11477  0.334
2012 Madala SK, Edukulla R, Davis KR, Schmidt S, Davidson C, Kitzmiller JA, Hardie WD, Korfhagen TR. Resistin-like molecule α1 (Fizz1) recruits lung dendritic cells without causing pulmonary fibrosis. Respiratory Research. 13: 51. PMID 22726462 DOI: 10.1186/1465-9921-13-51  0.416
2012 Madala SK, Schmidt S, Davidson C, Ikegami M, Wert S, Hardie WD. MEK-ERK pathway modulation ameliorates pulmonary fibrosis associated with epidermal growth factor receptor activation. American Journal of Respiratory Cell and Molecular Biology. 46: 380-8. PMID 22021337 DOI: 10.1165/rcmb.2011-0237OC  0.465
2011 Kramer EL, Hardie WD, Mushaben EM, Acciani TH, Pastura PA, Korfhagen TR, Hershey GK, Whitsett JA, Le Cras TD. Rapamycin decreases airway remodeling and hyperreactivity in a transgenic model of noninflammatory lung disease. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 1760-7. PMID 21903885 DOI: 10.1152/japplphysiol.00737.2011  0.381
2011 Madala SK, Maxfield MD, Davidson CR, Schmidt SM, Garry D, Ikegami M, Hardie WD, Glasser SW. Rapamycin Regulates Bleomycin-Induced Lung Damage in SP-C-Deficient Mice. Pulmonary Medicine. 2011: 653524. PMID 21660239 DOI: 10.1155/2011/653524  0.456
2010 Glasser SW, Hardie WD, Hagood JS. Pathogenesis of Interstitial Lung Disease in Children and Adults. Pediatric Allergy, Immunology, and Pulmonology. 23: 9-14. PMID 22087431 DOI: 10.1089/Ped.2010.0004  0.367
2010 Hardie WD, Hagood JS, Dave V, Perl AK, Whitsett JA, Korfhagen TR, Glasser S. Signaling pathways in the epithelial origins of pulmonary fibrosis. Cell Cycle (Georgetown, Tex.). 9: 2769-76. PMID 20676040 DOI: 10.4161/cc.9.14.12268  0.438
2010 Le Cras TD, Korfhagen TR, Davidson C, Schmidt S, Fenchel M, Ikegami M, Whitsett JA, Hardie WD. Inhibition of PI3K by PX-866 prevents transforming growth factor-alpha-induced pulmonary fibrosis. The American Journal of Pathology. 176: 679-86. PMID 20042669 DOI: 10.2353/Ajpath.2010.090123  0.525
2009 Deshmukh HS, McLachlan A, Atkinson JJ, Hardie WD, Korfhagen TR, Dietsch M, Liu Y, Di PY, Wesselkamper SC, Borchers MT, Leikauf GD. Matrix metalloproteinase-14 mediates a phenotypic shift in the airways to increase mucin production. American Journal of Respiratory and Critical Care Medicine. 180: 834-45. PMID 19661247 DOI: 10.1164/Rccm.200903-0328Oc  0.314
2009 Hardie WD, Glasser SW, Hagood JS. Emerging concepts in the pathogenesis of lung fibrosis. The American Journal of Pathology. 175: 3-16. PMID 19497999 DOI: 10.2353/Ajpath.2009.081170  0.466
2009 Korfhagen TR, Le Cras TD, Davidson CR, Schmidt SM, Ikegami M, Whitsett JA, Hardie WD. Rapamycin prevents transforming growth factor-alpha-induced pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 41: 562-72. PMID 19244201 DOI: 10.1165/rcmb.2008-0377OC  0.473
2009 Kramer EL, Mushaben EM, Pastura PA, Acciani TH, Deutsch GH, Khurana Hershey GK, Korfhagen TR, Hardie WD, Whitsett JA, Le Cras TD. Early growth response-1 suppresses epidermal growth factor receptor-mediated airway hyperresponsiveness and lung remodeling in mice. American Journal of Respiratory Cell and Molecular Biology. 41: 415-25. PMID 19188657 DOI: 10.1165/Rcmb.2008-0470Oc  0.52
2009 Bein K, Wesselkamper SC, Liu X, Dietsch M, Majumder N, Concel VJ, Medvedovic M, Sartor MA, Henning LN, Venditto C, Borchers MT, Barchowsky A, Weaver TE, Tichelaar JW, Prows DR, ... ... Hardie WD, et al. Surfactant-associated protein B is critical to survival in nickel-induced injury in mice. American Journal of Respiratory Cell and Molecular Biology. 41: 226-36. PMID 19131640 DOI: 10.1165/Rcmb.2008-0317Oc  0.32
2008 Hardie WD, Davidson C, Ikegami M, Leikauf GD, Le Cras TD, Prestridge A, Whitsett JA, Korfhagen TR. EGF receptor tyrosine kinase inhibitors diminish transforming growth factor-alpha-induced pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 294: L1217-25. PMID 18424623 DOI: 10.1152/Ajplung.00020.2008  0.519
2007 Hardie WD, Korfhagen TR, Sartor MA, Prestridge A, Medvedovic M, Le Cras TD, Ikegami M, Wesselkamper SC, Davidson C, Dietsch M, Nichols W, Whitsett JA, Leikauf GD. Genomic profile of matrix and vasculature remodeling in TGF-alpha induced pulmonary fibrosis. American Journal of Respiratory Cell and Molecular Biology. 37: 309-21. PMID 17496152 DOI: 10.1165/Rcmb.2006-0455Oc  0.496
2007 Kramer EL, Deutsch GH, Sartor MA, Hardie WD, Ikegami M, Korfhagen TR, Le Cras TD. Perinatal increases in TGF-{alpha} disrupt the saccular phase of lung morphogenesis and cause remodeling: microarray analysis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 293: L314-27. PMID 17468132 DOI: 10.1152/Ajplung.00354.2006  0.464
2005 Ikegami M, Le Cras TD, Hardie WD, Stahlman MT, Whitsett JA, Korfhagen TR. TGF-alpha perturbs surfactant homeostasis in vivo. American Journal of Physiology. Lung Cellular and Molecular Physiology. 289: L34-43. PMID 15764643 DOI: 10.1152/ajplung.00407.2004  0.317
2004 Le Cras TD, Hardie WD, Deutsch GH, Albertine KH, Ikegami M, Whitsett JA, Korfhagen TR. Transient induction of TGF-alpha disrupts lung morphogenesis, causing pulmonary disease in adulthood. American Journal of Physiology. Lung Cellular and Molecular Physiology. 287: L718-29. PMID 15090366 DOI: 10.1152/ajplung.00084.2004  0.428
2004 Hardie WD, Le Cras TD, Jiang K, Tichelaar JW, Azhar M, Korfhagen TR. Conditional expression of transforming growth factor-alpha in adult mouse lung causes pulmonary fibrosis. American Journal of Physiology. Lung Cellular and Molecular Physiology. 286: L741-9. PMID 14660483 DOI: 10.1152/Ajplung.00208.2003  0.469
2003 Le Cras TD, Hardie WD, Fagan K, Whitsett JA, Korfhagen TR. Disrupted pulmonary vascular development and pulmonary hypertension in transgenic mice overexpressing transforming growth factor-alpha. American Journal of Physiology. Lung Cellular and Molecular Physiology. 285: L1046-54. PMID 12896876 DOI: 10.1152/ajplung.00045.2003  0.398
2002 Hardie WD, Prows DR, Piljan-Gentle A, Dunlavy MR, Wesselkamper SC, Leikauf GD, Korfhagen TR. Dose-related protection from nickel-induced lung injury in transgenic mice expressing human transforming growth factor-alpha. American Journal of Respiratory Cell and Molecular Biology. 26: 430-7. PMID 11919079 DOI: 10.1165/Ajrcmb.26.4.4594  0.365
2002 Leikauf GD, McDowell SA, Wesselkamper SC, Hardie WD, Leikauf JE, Korfhagen TR, Prows DR. Acute lung injury: functional genomics and genetic susceptibility. Chest. 121: 70S-75S. PMID 11893692 DOI: 10.1378/Chest.121.3_Suppl.70S  0.305
2001 Leikauf GD, McDowell SA, Bachurski CJ, Aronow BJ, Gammon K, Wesselkamper SC, Hardie W, Wiest JS, Leikauf JE, Korfhagen TR, Prows DR. Functional genomics of oxidant-induced lung injury Advances in Experimental Medicine and Biology. 500: 479-487. PMID 11764985 DOI: 10.1007/978-1-4615-0667-6_73  0.333
2001 Hardie WD, Piljan-Gentle A, Dunlavy MR, Ikegami M, Korfhagen TR. Dose-dependent lung remodeling in transgenic mice expressing transforming growth factor-alpha. American Journal of Physiology. Lung Cellular and Molecular Physiology. 281: L1088-94. PMID 11597899  0.36
1999 Hardie WD, Prows DR, Leikauf GD, Korfhagen TR. Attenuation of acute lung injury in transgenic mice expressing human transforming growth factor-α. American Journal of Physiology. Lung Cellular and Molecular Physiology. 277: L1045-L1050. PMID 29592312 DOI: 10.1152/ajplung.1999.277.5.L1045  0.374
1999 Hardie WD, Prows DR, Leikauf GD, Korfhagen TR. Attenuation of acute lung injury in transgenic mice expressing human transforming growth factor-alpha. The American Journal of Physiology. 277: L1045-50. PMID 10564191 DOI: 10.1152/Ajplung.1999.277.5.L1045  0.401
1999 Hardie WD, Bejarano PA, Miller MA, Yankaskas JR, Ritter JH, Whitsett JA, Korfhagen TR. Immunolocalization of transforming growth factor alpha and epidermal growth factor receptor in lungs of patients with cystic fibrosis. Pediatric and Developmental Pathology : the Official Journal of the Society For Pediatric Pathology and the Paediatric Pathology Society. 2: 415-23. PMID 10441618 DOI: 10.1007/S100249900144  0.49
1997 Hardie WD, Bruno MD, Huelsman KM, Iwamoto HS, Carrigan PE, Leikauf GD, Whitsett JA, Korfhagen TR. Postnatal lung function and morphology in transgenic mice expressing transforming growth factor-alpha. The American Journal of Pathology. 151: 1075-83. PMID 9327741  0.474
1996 Hardie WD, Kerlakian CB, Bruno MD, Huelsman KM, Wert SE, Glasser SW, Whitsett JA, Korfhagen TR. Reversal of lung lesions in transgenic transforming growth factor alpha mice by expression of mutant epidermal growth factor receptor. American Journal of Respiratory Cell and Molecular Biology. 15: 499-508. PMID 8879184 DOI: 10.1165/ajrcmb.15.4.8879184  0.333
1992 Hardie WD, Wheeler AP, Wright PW, Swindell BB, Bernard GR. Effect of cyclooxygenase inhibition on amphotericin B-induced lung injury in awake sheep. The Journal of Infectious Diseases. 166: 134-8. PMID 1607684 DOI: 10.1093/infdis/166.1.134  0.323
1991 Hardie WD, Wright PE, Bernard GR. Effects of intravenous amphotericin B infusion on hemodynamics and airway mechanics in awake sheep. Chest. 99: 457-62. PMID 1989809  0.309
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