Lauge L. Farnaes, Ph.D.

Affiliations: 
Oceanography University of California, San Diego, La Jolla, CA 
Area:
Natural Products Chemistry
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"Lauge Farnaes"

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William H. Fenical grad student 2009 UCSD
 (Novel analogs and a protein target for the napyradiomycins.)
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Publications

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Ramchandar N, Ding Y, Farnaes L, et al. (2020) Diagnosis of cytomegalovirus infection from clinical whole genome sequencing. Scientific Reports. 10: 11020
Kingsmore SF, Cakici JA, Clark MM, et al. (2019) A Randomized, Controlled Trial of the Analytic and Diagnostic Performance of Singleton and Trio, Rapid Genome and Exome Sequencing in Ill Infants. American Journal of Human Genetics
Sanford EF, Clark MM, Farnaes L, et al. (2019) Rapid Whole Genome Sequencing Has Clinical Utility in Children in the PICU. Pediatric Critical Care Medicine : a Journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies
Clark MM, Hildreth A, Batalov S, et al. (2019) Diagnosis of genetic diseases in seriously ill children by rapid whole-genome sequencing and automated phenotyping and interpretation. Science Translational Medicine. 11
Farnaes L, Wilke J, Ryan Loker K, et al. (2019) Community-acquired pneumonia in children: cell-free plasma sequencing for diagnosis and management. Diagnostic Microbiology and Infectious Disease
Farnaes L, Hildreth A, Sweeney NM, et al. (2018) Rapid whole-genome sequencing decreases infant morbidity and cost of hospitalization. Npj Genomic Medicine. 3: 10
Farnaes L, Coufal NG, Kauffman CA, et al. (2014) Napyradiomycin derivatives, produced by a marine-derived actinomycete, illustrate cytotoxicity by induction of apoptosis. Journal of Natural Products. 77: 15-21
Farnaes L, La Clair JJ, Fenical W. (2014) Napyradiomycins CNQ525.510B and A80915C target the Hsp90 paralogue Grp94 Organic and Biomolecular Chemistry. 12: 418-423
Haste NM, Farnaes L, Perera VR, et al. (2011) Bactericidal kinetics of marine-derived napyradiomycins against contemporary methicillin-resistant Staphylococcus aureus Marine Drugs. 9: 680-689
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