Jeffrey B. Locke, Ph.D.

Affiliations: 
2008 Marine Biology University of California, San Diego, La Jolla, CA 
Area:
Microbiology, Oceanography
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"Jeffrey Locke"

Parents

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Douglas H. Bartlett grad student 2008 UCSD
 (Characterization of virulence factors in the aquatic pathogen Streptococcus iniae.)
Victor Nizet grad student 2005-2008 UCSD (Microtree)
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Publications

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Locke JB, Zurenko GE, Shaw KJ, et al. (2014) Tedizolid for the management of human infections: in vitro characteristics. Clinical Infectious Diseases : An Official Publication of the Infectious Diseases Society of America. 58: S35-42
Carland TM, Locke JB, Nizet V, et al. (2012) Differential expression and intrachromosomal evolution of the sghC1q genes in zebrafish (Danio rerio). Developmental and Comparative Immunology. 36: 31-8
Locke JB, Vicknair MR, Ostland VE, et al. (2010) Evaluation of Streptococcus iniae killed bacterin and live attenuated vaccines in hybrid striped bass through injection and bath immersion. Diseases of Aquatic Organisms. 89: 117-23
Milani CJ, Aziz RK, Locke JB, et al. (2010) The novel polysaccharide deacetylase homologue Pdi contributes to virulence of the aquatic pathogen Streptococcus iniae. Microbiology (Reading, England). 156: 543-54
Zinkernagel AS, Timmer AM, Pence MA, et al. (2008) The IL-8 protease SpyCEP/ScpC of group A Streptococcus promotes resistance to neutrophil killing. Cell Host & Microbe. 4: 170-8
Locke JB, Aziz RK, Vicknair MR, et al. (2008) Streptococcus iniae M-like protein contributes to virulence in fish and is a target for live attenuated vaccine development. Plos One. 3: e2824
Carland TM, Locke JB, Nizet V, et al. (2008) Transcriptional studies of a novel family of “short C1q” domain proteins in zebrafish The Faseb Journal. 22: 558-558
Locke JB, Colvin KM, Varki N, et al. (2007) Streptococcus iniae beta-hemolysin streptolysin S is a virulence factor in fish infection. Diseases of Aquatic Organisms. 76: 17-26
Locke JB, Colvin KM, Datta AK, et al. (2007) Streptococcus iniae capsule impairs phagocytic clearance and contributes to virulence in fish. Journal of Bacteriology. 189: 1279-87
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