Year |
Citation |
Score |
2015 |
Grondin R, Ge P, Chen Q, Sutherland JE, Zhang Z, Gash DM, Stiles DK, Stewart GR, Sah DW, Kaemmerer WF. Onset Time and Durability of Huntingtin Suppression in Rhesus Putamen After Direct Infusion of Antihuntingtin siRNA. Molecular Therapy. Nucleic Acids. 4: e245. PMID 26125484 DOI: 10.1038/Mtna.2015.20 |
0.342 |
|
2012 |
Grondin R, Kaytor MD, Ai Y, Nelson PT, Thakker DR, Heisel J, Weatherspoon MR, Blum JL, Burright EN, Zhang Z, Kaemmerer WF. Six-month partial suppression of Huntingtin is well tolerated in the adult rhesus striatum. Brain : a Journal of Neurology. 135: 1197-209. PMID 22252996 DOI: 10.1093/Brain/Awr333 |
0.392 |
|
2012 |
Stiles DK, Zhang Z, Ge P, Nelson B, Grondin R, Ai Y, Hardy P, Nelson PT, Guzaev AP, Butt MT, Charisse K, Kosovrasti V, Tchangov L, Meys M, Maier M, ... ... Kaemmerer WF, et al. Widespread suppression of huntingtin with convection-enhanced delivery of siRNA. Experimental Neurology. 233: 463-71. PMID 22119622 DOI: 10.1016/J.Expneurol.2011.11.020 |
0.365 |
|
2009 |
Lombardi MS, Jaspers L, Spronkmans C, Gellera C, Taroni F, Di Maria E, Donato SD, Kaemmerer WF. A majority of Huntington's disease patients may be treatable by individualized allele-specific RNA interference. Experimental Neurology. 217: 312-9. PMID 19289118 DOI: 10.1016/J.Expneurol.2009.03.004 |
0.307 |
|
2008 |
Belur LR, Kaemmerer WF, McIvor RS, Low WC. Adeno-associated virus type 2 vectors: transduction and long-term expression in cerebellar Purkinje cells in vivo is mediated by the fibroblast growth factor receptor 1 : bFGFR-1 mediates AAV2 transduction of Purkinje cells. Archives of Virology. 153: 2107-10. PMID 18937030 DOI: 10.1007/S00705-008-0222-7 |
0.456 |
|
2008 |
van Bilsen PH, Jaspers L, Lombardi MS, Odekerken JC, Burright EN, Kaemmerer WF. Identification and allele-specific silencing of the mutant huntingtin allele in Huntington's disease patient-derived fibroblasts. Human Gene Therapy. 19: 710-9. PMID 18549309 DOI: 10.1089/Hum.2007.116 |
0.339 |
|
2002 |
Pan D, Gunther R, Duan W, Wendell S, Kaemmerer W, Kafri T, Verma IM, Whitley CB. Biodistribution and toxicity studies of VSVG-pseudotyped lentiviral vector after intravenous administration in mice with the observation of in vivo transduction of bone marrow. Molecular Therapy : the Journal of the American Society of Gene Therapy. 6: 19-29. PMID 12095299 DOI: 10.1006/Mthe.2002.0630 |
0.359 |
|
2001 |
Kaemmerer WF, Rodrigues CM, Steer CJ, Low WC. Creatine-supplemented diet extends Purkinje cell survival in spinocerebellar ataxia type 1 transgenic mice but does not prevent the ataxic phenotype. Neuroscience. 103: 713-24. PMID 11274790 DOI: 10.1016/S0306-4522(01)00017-3 |
0.486 |
|
2000 |
Kaemmerer WF, Reddy RG, Warlick CA, Hartung SD, McIvor RS, Low WC. In vivo transduction of cerebellar Purkinje cells using adeno-associated virus vectors. Molecular Therapy : the Journal of the American Society of Gene Therapy. 2: 446-57. PMID 11082318 DOI: 10.1006/Mthe.2000.0134 |
0.473 |
|
1999 |
Kaemmerer WF, Low WC. Cerebellar allografts survive and transiently alleviate ataxia in a transgenic model of spinocerebellar ataxia type-1. Experimental Neurology. 158: 301-11. PMID 10415138 DOI: 10.1006/Exnr.1999.7099 |
0.471 |
|
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