Michael A. Dyer - Publications

Affiliations: 
St. Jude Children's Research Hospital, San Francisco, CA, United States 
Area:
Neurogenesis
Website:
https://www.stjude.org/dyer

123 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Honnell V, Sweeney S, Norrie J, Ramirez C, Xu B, Teubner B, Lee AY, Bell C, Dyer MA. Identification of Evolutionarily Conserved VSX2 Enhancers in Retinal Development. Biorxiv : the Preprint Server For Biology. PMID 37905144 DOI: 10.1101/2023.10.17.562742  0.392
2023 Norrie JL, Lupo M, Shirinifard A, Djekidel N, Ramirez C, Xu B, Dundee JM, Dyer MA. Latent Epigenetic Programs in Müller Glia Contribute to Stress, Injury, and Disease Response in the Retina. Biorxiv : the Preprint Server For Biology. PMID 37905050 DOI: 10.1101/2023.10.15.562396  0.354
2022 Whitney IE, Butrus S, Dyer MA, Rieke F, Sanes JR, Shekhar K. Vision-Dependent and -Independent Molecular Maturation of Mouse Retinal Ganglion Cells. Neuroscience. PMID 35870562 DOI: 10.1016/j.neuroscience.2022.07.013  0.333
2022 Van Gelder RN, Chiang MF, Dyer MA, Greenwell TN, Levin LA, Wong RO, Svendsen CN. Regenerative and restorative medicine for eye disease. Nature Medicine. 28: 1149-1156. PMID 35715505 DOI: 10.1038/s41591-022-01862-8  0.331
2022 Honnell V, Norrie JL, Patel AG, Ramirez C, Zhang J, Lai YH, Wan S, Dyer MA. Identification of a modular super-enhancer in murine retinal development. Nature Communications. 13: 253. PMID 35017532 DOI: 10.1038/s41467-021-27924-y  0.801
2021 Norrie JL, Nityanandam A, Lai K, Chen X, Wilson M, Stewart E, Griffiths L, Jin H, Wu G, Orr B, Tran Q, Allen S, Reilly C, Zhou X, Zhang J, ... ... Dyer MA, et al. Retinoblastoma from human stem cell-derived retinal organoids. Nature Communications. 12: 4535. PMID 34315877 DOI: 10.1038/s41467-021-24781-7  0.359
2020 Nguyen R, Patel AG, Griffiths LM, Dapper J, Stewart EA, Houston J, Johnson M, Akers WJ, Furman WL, Dyer MA. Next-generation humanized patient-derived xenograft mouse model for pre-clinical antibody studies in neuroblastoma. Cancer Immunology, Immunotherapy : Cii. PMID 32915319 DOI: 10.1007/S00262-020-02713-6  0.442
2020 Slyper M, Porter CBM, Ashenberg O, Waldman J, Drokhlyansky E, Wakiro I, Smillie C, Smith-Rosario G, Wu J, Dionne D, Vigneau S, Jané-Valbuena J, Tickle TL, Napolitano S, Su MJ, ... ... Dyer MA, et al. Author Correction: A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors. Nature Medicine. PMID 32587393 DOI: 10.1038/S41591-020-0976-3  0.311
2020 Slyper M, Porter CBM, Ashenberg O, Waldman J, Drokhlyansky E, Wakiro I, Smillie C, Smith-Rosario G, Wu J, Dionne D, Vigneau S, Jané-Valbuena J, Tickle TL, Napolitano S, Su MJ, ... ... Dyer MA, et al. A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors. Nature Medicine. 26: 792-802. PMID 32405060 DOI: 10.1038/S41591-020-0844-1  0.356
2020 Zeineldin M, Federico S, Chen X, Fan Y, Xu B, Stewart E, Zhou X, Jeon J, Griffiths L, Nguyen R, Norrie J, Easton J, Mulder H, Yergeau D, Liu Y, ... ... Dyer MA, et al. MYCN amplification and ATRX mutations are incompatible in neuroblastoma. Nature Communications. 11: 913. PMID 32060267 DOI: 10.1038/S41467-020-14682-6  0.362
2020 Moustaki A, Crawford JC, Alli S, Zamora A, Fan Y, Boi S, McDonald NM, Thomas PG, Pappo AS, Dyer MA, Stewart E, Federico S, Youngblood B. Abstract LB-074: Antigen-cross presentation promotes development of terminally differentiated CD8 T cells in young individuals Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Lb-074  0.37
2020 Dunphy PS, Xu K, Gentry DT, He C, Mercer K, Zhu X, Smith K, Gudenas B, Robinson S, Zhang J, Kasper LH, Kwon C, Hover LD, Larson JD, Twarog N, ... ... Dyer MA, et al. Abstract 6144: St. Jude Pediatric Brain Tumor Portal: Cloud-based resource for patient-derived orthotopic xenograft (PDOX) models of pediatric high-grade glioma, ependymoma, and CNS embryonal tumors Tumor Biology. DOI: 10.1158/1538-7445.Am2020-6144  0.303
2019 Norrie JL, Lupo MS, Xu B, Al Diri I, Valentine M, Putnam D, Griffiths L, Zhang J, Johnson D, Easton J, Shao Y, Honnell V, Frase S, Miller S, Stewart V, ... ... Dyer MA, et al. Nucleome Dynamics during Retinal Development. Neuron. PMID 31493975 DOI: 10.1016/J.Neuron.2019.08.002  0.731
2019 Brady SW, Ma X, Bahrami A, Satas G, Wu G, Newman S, Rusch M, Putnam DK, Mulder HL, Yergeau D, Edmonson MN, Easton J, Alexandrov LB, Chen X, Mardis ER, ... ... Dyer MA, et al. The Clonal Evolution of Metastatic Osteosarcoma as Shaped by Cisplatin Treatment. Molecular Cancer Research : McR. PMID 30651371 DOI: 10.1158/1541-7786.Mcr-18-0620  0.335
2019 Patel AG, Stewart E, Clay M, Chen X, Dyer M. Abstract 3768: Single-cell characterization and lineage tracking of recurrent pediatric rhabdomyosarcoma Cancer Research. 79: 3768-3768. DOI: 10.1158/1538-7445.Am2019-3768  0.395
2018 Loh A, Bradley C, Karlstrom A, Krafcik F, Dyer MA, Stewart E, Goshorn R, Chen X, Daryani V, Stewart C, Calabrese C, Funk A, Miller G, Shelat A, Bahrami A. Combinatorial Screening Using Orthotopic Patient Derived Xenograft-Expanded Early Phase Cultures of Osteosarcoma Identify Novel Therapeutic Drug Combinations. Cancer Letters. PMID 30395907 DOI: 10.1016/J.Canlet.2018.10.033  0.38
2018 Stewart E, McEvoy J, Wang H, Chen X, Honnell V, Ocarz M, Gordon B, Dapper J, Blankenship K, Yang Y, Li Y, Shaw TI, Cho JH, Wang X, Xu B, ... ... Dyer MA, et al. Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses. Cancer Cell. PMID 30146332 DOI: 10.1016/J.Ccell.2018.07.012  0.773
2018 Wang L, Hiler D, Xu B, AlDiri I, Chen X, Zhou X, Griffiths L, Valentine M, Shirinifard A, Sablauer A, Thiagarajan S, Barabas ME, Zhang J, Johnson D, Frase S, ... Dyer MA, et al. Retinal Cell Type DNA Methylation and Histone Modifications Predict Reprogramming Efficiency and Retinogenesis in 3D Organoid Cultures. Cell Reports. 22: 2601-2614. PMID 29514090 DOI: 10.1016/J.Celrep.2018.01.075  0.384
2018 Nguyen R, Houston J, Chan WK, Finkelstein D, Dyer MA. The role of interleukin-2, all-trans retinoic acid, and natural killer cells: surveillance mechanisms in anti-GD2 antibody therapy in neuroblastoma. Cancer Immunology, Immunotherapy : Cii. PMID 29327110 DOI: 10.1007/s00262-017-2108-6  0.371
2018 Zeineldin M, Federico SM, Griffith L, Jeon J, Chen X, Easton J, Wu J, Mao S, Liu Y, Naranjo A, Pappo AS, Hogarty MD, Dyer MA. Abstract PR11: Synthetic lethality between ATRX mutations and MYCN amplification in neuroblastoma Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-Pr11  0.391
2018 Zeineldin M, Federico S, Chen X, Xu B, Stewart E, Naranjo A, Hogarty MD, Dyer MA. Abstract IA18: MYCN amplification and ATRX mutations are incompatible in neuroblastoma Cancer Research. 78. DOI: 10.1158/1538-7445.Pedca17-Ia18  0.346
2017 Chang TC, Carter RA, Li Y, Li Y, Wang H, Edmonson MN, Chen X, Arnold P, Geiger TL, Wu G, Peng J, Dyer M, Downing JR, Green DR, Thomas PG, et al. The neoepitope landscape in pediatric cancers. Genome Medicine. 9: 78. PMID 28854978 DOI: 10.1186/S13073-017-0468-3  0.337
2017 Stewart E, Federico SM, Chen X, Shelat AA, Bradley C, Gordon B, Karlstrom A, Twarog NR, Clay MR, Bahrami A, Freeman BB, Xu B, Zhou X, Wu J, Honnell V, ... ... Dyer MA, et al. Orthotopic patient-derived xenografts of paediatric solid tumours. Nature. PMID 28854174 DOI: 10.1038/Nature23647  0.752
2017 Aldiri I, Xu B, Wang L, Chen X, Hiler D, Griffiths L, Valentine M, Shirinifard A, Thiagarajan S, Sablauer A, Barabas ME, Zhang J, Johnson D, Frase S, Zhou X, ... ... Dyer MA, et al. The Dynamic Epigenetic Landscape of the Retina During Development, Reprogramming, and Tumorigenesis. Neuron. 94: 550-568.e10. PMID 28472656 DOI: 10.1016/J.Neuron.2017.04.022  0.467
2017 Dyer MA, Qadeer ZA, Valle-Garcia D, Bernstein E. ATRX and DAXX: Mechanisms and Mutations. Cold Spring Harbor Perspectives in Medicine. PMID 28062559 DOI: 10.1101/Cshperspect.A026567  0.336
2017 Stewart E, Honnell V, Ocarz M, Blankenship K, Dapper J, Freeman B, Shelat A, Pappo AS, Dyer MA. Targeting the cell cycle for cancer therapy in rhabdomyosarcoma. Journal of Clinical Oncology. 35: 10535-10535. DOI: 10.1200/Jco.2017.35.15_Suppl.10535  0.312
2016 Dyer MA. Biomedicine: An eye on retinal recovery. Nature. PMID 27919071 DOI: 10.1038/nature20487  0.366
2016 Hiler DJ, Barabas ME, Griffiths LM, Dyer MA. Reprogramming of mouse retinal neurons and standardized quantification of their differentiation in 3D retinal cultures. Nature Protocols. 11: 1955-1976. PMID 27658012 DOI: 10.1038/Nprot.2016.109  0.436
2016 Dyer MA. Lessons from Retinoblastoma: Implications for Cancer, Development, Evolution, and Regenerative Medicine. Trends in Molecular Medicine. PMID 27567287 DOI: 10.1016/j.molmed.2016.07.010  0.391
2016 Valle-García D, Qadeer ZA, McHugh DS, Ghiraldini FG, Chowdhury AH, Hasson D, Dyer MA, Recillas-Targa F, Bernstein E. ATRX binds to atypical chromatin domains at the 3' exons of zinc finger genes to preserve H3K9me3 enrichment. Epigenetics. 0. PMID 27029610 DOI: 10.1080/15592294.2016.1169351  0.35
2016 Grace CR, Ban D, Min J, Mayasundari A, Min L, Finch KE, Griffiths L, Bharatham N, Bashford D, Kiplin Guy R, Dyer MA, Kriwacki RW. Monitoring ligand-induced protein ordering in drug discovery. Journal of Molecular Biology. PMID 26812210 DOI: 10.1016/J.Jmb.2016.01.016  0.306
2016 Dyer M. Abstract IA17: Dynamic changes in the epigenetic landscape during retinal development, cellular reprogramming, and tumorigenesis Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Devbiolca15-Ia17  0.488
2016 Dyer M. Abstract IA12: Targeting the cell cycle in pediatric solid tumors Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Cellcycle16-Ia12  0.407
2016 Stewart E, Bradley C, Shelat A, Pappo A, Dyer MA. Abstract A09: Preclinical trial using the combination of panobinostat with bortezomib in human orthotopic xenograft mouse models of rhabdomyosarcoma Cancer Research. 76. DOI: 10.1158/1538-7445.Pedca15-A09  0.331
2015 Aldiri I, Ajioka I, Xu B, Zhang J, Chen X, Benavente C, Finkelstein D, Johnson D, Akiyama J, Pennacchio LA, Dyer MA. Brg1 coordinates multiple processes during retinogenesis and is a tumor suppressor in retinoblastoma. Development (Cambridge, England). 142: 4092-106. PMID 26628093 DOI: 10.1242/Dev.124800  0.806
2015 Langenau DM, Sweet-Cordero A, Wechsler-Reya RJ, Dyer MA. Preclinical Models Provide Scientific Justification and Translational Relevance for Moving Novel Therapeutics into Clinical Trials for Pediatric Cancer. Cancer Research. PMID 26627009 DOI: 10.1158/0008-5472.Can-15-1308  0.357
2015 McEvoy JD, Dyer MA. Genetic and Epigenetic Discoveries in Human Retinoblastoma. Critical Reviews in Oncogenesis. 20: 217-25. PMID 26349417 DOI: 10.1615/Critrevoncog.2015013711  0.419
2015 Pritchard EM, Dyer MA, Guy RK. Progress in Small Molecule Therapeutics for the Treatment of Retinoblastoma. Mini Reviews in Medicinal Chemistry. PMID 26202204 DOI: 10.2174/1389557515666150722100610  0.337
2015 Hiler D, Chen X, Hazen J, Kupriyanov S, Carroll PA, Qu C, Xu B, Johnson D, Griffiths L, Frase S, Rodriguez AR, Martin G, Zhang J, Jeon J, Fan Y, ... ... Dyer MA, et al. Quantification of Retinogenesis in 3D Cultures Reveals Epigenetic Memory and Higher Efficiency in iPSCs Derived from Rod Photoreceptors. Cell Stem Cell. 17: 101-115. PMID 26140606 DOI: 10.1016/J.Stem.2015.05.015  0.389
2015 Stewart E, Federico S, Karlstrom A, Shelat A, Sablauer A, Pappo A, Dyer MA. The Childhood Solid Tumor Network: A new resource for the developmental biology and oncology research communities. Developmental Biology. PMID 26068307 DOI: 10.1016/J.Ydbio.2015.03.001  0.379
2015 Moriarity BS, Otto GM, Rahrmann EP, Rathe SK, Wolf NK, Weg MT, Manlove LA, LaRue RS, Temiz NA, Molyneux SD, Choi K, Holly KJ, Sarver AL, Scott MC, Forster CL, ... ... Dyer MA, et al. A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis. Nature Genetics. 47: 615-24. PMID 25961939 DOI: 10.1038/Ng.3293  0.354
2015 Stewart E, Federico S, Karlstrom A, Shelat A, Sablauer A, Pappo A, Dyer MA. The childhood solid tumor network: A new resource for the developmental biology and oncology research communities. Developmental Biology. PMID 25863122 DOI: 10.1016/J.Ydbio.2015.02.002  0.404
2015 Gupte A, Baker EK, Wan SS, Stewart E, Loh A, Shelat AA, Gould CM, Chalk AM, Taylor S, Lackovic K, Karlström Å, Mutsaers AJ, Desai J, Madhamshettiwar PB, Zannettino AC, ... ... Dyer MA, et al. Systematic Screening Identifies Dual PI3K and mTOR Inhibition as a Conserved Therapeutic Vulnerability in Osteosarcoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 3216-29. PMID 25862761 DOI: 10.1158/1078-0432.Ccr-14-3026  0.337
2015 Pinto EM, Chen X, Easton J, Finkelstein D, Liu Z, Pounds S, Rodriguez-Galindo C, Lund TC, Mardis ER, Wilson RK, Boggs K, Yergeau D, Cheng J, Mulder HL, Manne J, ... ... Dyer MA, et al. Genomic landscape of paediatric adrenocortical tumours. Nature Communications. 6: 6302. PMID 25743702 DOI: 10.1038/ncomms7302  0.336
2015 Chen X, Pappo A, Dyer MA. Pediatric solid tumor genomics and developmental pliancy. Oncogene. PMID 25639868 DOI: 10.1038/onc.2014.474  0.38
2015 Benavente CA, Dyer MA. Genetically engineered mouse and orthotopic human tumor xenograft models of retinoblastoma. Methods in Molecular Biology (Clifton, N.J.). 1267: 307-17. PMID 25636476 DOI: 10.1007/978-1-4939-2297-0_15  0.758
2015 Benavente CA, Dyer MA. Genetics and epigenetics of human retinoblastoma. Annual Review of Pathology. 10: 547-62. PMID 25621664 DOI: 10.1146/annurev-pathol-012414-040259  0.769
2015 Lu C, Zhang J, Nagahawatte P, Easton J, Lee S, Liu Z, Ding L, Wyczalkowski MA, Valentine M, Navid F, Mulder H, Tatevossian RG, Dalton J, Davenport J, Yin Z, ... ... Dyer M, et al. The genomic landscape of childhood and adolescent melanoma. The Journal of Investigative Dermatology. 135: 816-23. PMID 25268584 DOI: 10.1038/Jid.2014.425  0.326
2015 Bahrami A, Wu J, Dyer MA, Delattre O, Pappo AS. Loss of STAG2 expression and prognosis in Ewing sarcoma family of tumors. Journal of Clinical Oncology. 33: 10024-10024. DOI: 10.1200/JCO.2015.33.15_SUPPL.10024  0.305
2014 Stewart E, Goshorn R, Bradley C, Griffiths LM, Benavente C, Twarog NR, Miller GM, Caufield W, Freeman BB, Bahrami A, Pappo A, Wu J, Loh A, Karlström Å, Calabrese C, ... ... Dyer MA, et al. Targeting the DNA repair pathway in Ewing sarcoma. Cell Reports. 9: 829-41. PMID 25437539 DOI: 10.1016/J.Celrep.2014.09.028  0.747
2014 Benavente CA, Finkelstein D, Johnson DA, Marine JC, Ashery-Padan R, Dyer MA. Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression. Oncotarget. 5: 9594-608. PMID 25338120 DOI: 10.18632/Oncotarget.2468  0.787
2014 Tirode F, Surdez D, Ma X, Parker M, Le Deley MC, Bahrami A, Zhang Z, Lapouble E, Grossetête-Lalami S, Rusch M, Reynaud S, Rio-Frio T, Hedlund E, Wu G, Chen X, ... ... Dyer M, et al. Genomic landscape of Ewing sarcoma defines an aggressive subtype with co-association of STAG2 and TP53 mutations. Cancer Discovery. 4: 1342-53. PMID 25223734 DOI: 10.1158/2159-8290.Cd-14-0622  0.363
2014 Miles WO, Korenjak M, Griffiths LM, Dyer MA, Provero P, Dyson NJ. Post-transcriptional gene expression control by NANOS is up-regulated and functionally important in pRb-deficient cells. The Embo Journal. 33: 2201-15. PMID 25100735 DOI: 10.15252/Embj.201488057  0.443
2014 Valle-García D, Griffiths LM, Dyer MA, Bernstein E, Recillas-Targa F. The ATRX cDNA is prone to bacterial IS10 element insertions that alter its structure. Springerplus. 3: 222. PMID 24834375 DOI: 10.1186/2193-1801-3-222  0.317
2014 McEvoy J, Nagahawatte P, Finkelstein D, Richards-Yutz J, Valentine M, Ma J, Mullighan C, Song G, Chen X, Wilson M, Brennan R, Pounds S, Becksfort J, Huether R, Lu C, ... ... Dyer MA, et al. RB1 gene inactivation by chromothripsis in human retinoblastoma. Oncotarget. 5: 438-50. PMID 24509483 DOI: 10.18632/Oncotarget.1686  0.32
2014 Zhang H, Nieves JL, Fraser ST, Isern J, Douvaras P, Papatsenko D, D'Souza SL, Lemischka IR, Dyer MA, Baron MH. Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm. Stem Cells (Dayton, Ohio). 32: 191-203. PMID 24022884 DOI: 10.1002/Stem.1536  0.335
2014 Federico SM, Stewart E, Bradley C, McEvoy J, Loh A, Shelat A, Zhang J, Chen X, Pappo AS, Dyer MA. Molecular analysis of solid tumors (MAST): A protocol for comprehensive preclinical evaluation of pediatric solid tumors. Journal of Clinical Oncology. 32: 10036-10036. DOI: 10.1200/Jco.2014.32.15_Suppl.10036  0.301
2014 Dyer MA. Abstract IA05: Targeting the oxidative stress pathway in rhabdomyosarcoma Cancer Research. 74. DOI: 10.1158/1538-7445.Pedcan-Ia05  0.389
2014 Wierdl M, Tsurkan L, Tollemar V, Chi L, Stewart E, Dyer MA, Potter PM. Abstract 3109: ALK as a valid therapeutic target for the treatment of rhabdomyosarcoma Cancer Research. 74: 3109-3109. DOI: 10.1158/1538-7445.Am2014-3109  0.398
2013 Benavente CA, McEvoy JD, Finkelstein D, Wei L, Kang G, Wang YD, Neale G, Ragsdale S, Valentine V, Bahrami A, Temirov J, Pounds S, Zhang J, Dyer MA. Cross-species genomic and epigenomic landscape of retinoblastoma. Oncotarget. 4: 844-59. PMID 23765217 DOI: 10.18632/Oncotarget.1051  0.776
2013 Cheung NK, Dyer MA. Neuroblastoma: developmental biology, cancer genomics and immunotherapy. Nature Reviews. Cancer. 13: 397-411. PMID 23702928 DOI: 10.1038/Nrc3526  0.334
2012 Parker M, Chen X, Bahrami A, Dalton J, Rusch M, Wu G, Easton J, Cheung NK, Dyer M, Mardis ER, Wilson RK, Mullighan C, Gilbertson R, Baker SJ, Zambetti G, et al. Assessing telomeric DNA content in pediatric cancers using whole-genome sequencing data. Genome Biology. 13: R113. PMID 23232254 DOI: 10.1186/Gb-2012-13-12-R113  0.335
2012 McEvoy J, Ulyanov A, Brennan R, Wu G, Pounds S, Zhang J, Dyer MA. Analysis of MDM2 and MDM4 single nucleotide polymorphisms, mRNA splicing and protein expression in retinoblastoma. Plos One. 7: e42739. PMID 22916154 DOI: 10.1371/Journal.Pone.0042739  0.363
2012 Nittner D, Lambertz I, Clermont F, Mestdagh P, Köhler C, Nielsen SJ, Jochemsen A, Speleman F, Vandesompele J, Dyer MA, Schramm A, Schulte JH, Marine JC. Synthetic lethality between Rb, p53 and Dicer or miR-17-92 in retinal progenitors suppresses retinoblastoma formation. Nature Cell Biology. 14: 958-65. PMID 22864477 DOI: 10.1038/ncb2556  0.369
2012 Cheung NK, Zhang J, Lu C, Parker M, Bahrami A, Tickoo SK, Heguy A, Pappo AS, Federico S, Dalton J, Cheung IY, Ding L, Fulton R, Wang J, Chen X, ... ... Dyer MA, et al. Association of age at diagnosis and genetic mutations in patients with neuroblastoma. Jama. 307: 1062-71. PMID 22416102 DOI: 10.1001/Jama.2012.228  0.32
2012 Zhang J, Benavente CA, McEvoy J, Flores-Otero J, Ding L, Chen X, Ulyanov A, Wu G, Wilson M, Wang J, Brennan R, Rusch M, Manning AL, Ma J, Easton J, ... ... Dyer MA, et al. A novel retinoblastoma therapy from genomic and epigenetic analyses. Nature. 481: 329-34. PMID 22237022 DOI: 10.1038/Nature10733  0.761
2012 Federico SM, Stewart E, Brennan RC, Bradley C, Wang F, Freeman BB, Stewart CF, Wu J, Dyer MA. Comprehensive preclinical testing for neuroblastoma using orthotopic xenografts of a patient tumor. Journal of Clinical Oncology. 30: e13584-e13584. DOI: 10.1200/JCO.2012.30.15_SUPPL.E13584  0.39
2012 Brennan RC, Wilson MW, Dyer MA, Bahrami A. SYK expression in metastatic retinoblastoma. Journal of Clinical Oncology. 30: e13544-e13544. DOI: 10.1200/JCO.2012.30.15_SUPPL.E13544  0.386
2012 Parker MD, Wu G, Chen X, Rusch M, Bahrami A, Ding L, Mardis E, Mullighan C, Gilbertson R, Dyer MA, Wilson RK, Downing J, Zhang J. Abstract 4873: Comprehensive analysis of 160 whole-genome sequences reveals striking telomere alteration patterns in 9 pediatric cancers Cancer Research. 72: 4873-4873. DOI: 10.1158/1538-7445.Am2012-4873  0.355
2012 Chen X, Wang J, Roberts K, Pounds S, Dyer M, Mullighan C, Downing J, Zhang J. Abstract 2487: CONSERTING: an accurate method for detecting focal and gross somatic copy number alterations in cancer genome by next generation sequencing Cancer Research. 72: 2487-2487. DOI: 10.1158/1538-7445.Am2012-2487  0.332
2011 Martins RA, Davis D, Kerekes R, Zhang J, Bayazitov IT, Hiler D, Karakaya M, Frase S, Gleason S, Zakharenko SS, Johnson DA, Dyer MA. Retinoblastoma (Rb) regulates laminar dendritic arbor reorganization in retinal horizontal neurons. Proceedings of the National Academy of Sciences of the United States of America. 108: 21111-6. PMID 22160703 DOI: 10.1073/Pnas.1108141108  0.67
2011 McEvoy J, Flores-Otero J, Zhang J, Nemeth K, Brennan R, Bradley C, Krafcik F, Rodriguez-Galindo C, Wilson M, Xiong S, Lozano G, Sage J, Fu L, Louhibi L, Trimarchi J, ... ... Dyer MA, et al. Coexpression of normally incompatible developmental pathways in retinoblastoma genesis. Cancer Cell. 20: 260-75. PMID 21840489 DOI: 10.1016/J.Ccr.2011.07.005  0.743
2011 Teitz T, Stanke JJ, Federico S, Bradley CL, Brennan R, Zhang J, Johnson MD, Sedlacik J, Inoue M, Zhang ZM, Frase S, Rehg JE, Hillenbrand CM, Finkelstein D, Calabrese C, ... Dyer MA, et al. Preclinical models for neuroblastoma: establishing a baseline for treatment. Plos One. 6: e19133. PMID 21559450 DOI: 10.1371/journal.pone.0019133  0.405
2011 Federico S, Brennan R, Dyer MA. Childhood cancer and developmental biology a crucial partnership. Current Topics in Developmental Biology. 94: 1-13. PMID 21295682 DOI: 10.1016/B978-0-12-380916-2.00001-2  0.381
2011 Kerekes RA, Martins RA, Davis D, Karakaya M, Gleason S, Dyer MA. Automated tracing of horizontal neuron processes during retinal development. Neurochemical Research. 36: 583-93. PMID 21221777 DOI: 10.1007/S11064-010-0390-1  0.627
2011 Nemeth KM, Federico S, Carcaboso AM, Shen Y, Schaiquevich P, Zhang J, Egorin M, Stewart C, Dyer MA. Subconjunctival carboplatin and systemic topotecan treatment in preclinical models of retinoblastoma. Cancer. 117: 421-34. PMID 20818652 DOI: 10.1002/Cncr.25574  0.311
2011 Dyer MA. Abstract SY15-02: Comprehensive analysis of genetic and epigenetic factors contributing to tumorigenesis in retinoblastoma Cancer Research. 71. DOI: 10.1158/1538-7445.Am2011-Sy15-02  0.401
2011 Benavente CA, Dyer MA. Abstract A163: A role for epigenetic reprogramming in retinoblastoma tumorigenesis. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-A163  0.44
2010 Davis DM, Dyer MA. Retinal progenitor cells, differentiation, and barriers to cell cycle reentry. Current Topics in Developmental Biology. 93: 175-88. PMID 20959166 DOI: 10.1016/B978-0-12-385044-7.00006-0  0.456
2010 Reed D, Shen Y, Shelat AA, Arnold LA, Ferreira AM, Zhu F, Mills N, Smithson DC, Regni CA, Bashford D, Cicero SA, Schulman BA, Jochemsen AG, Guy RK, Dyer MA. Identification and characterization of the first small molecule inhibitor of MDMX. The Journal of Biological Chemistry. 285: 10786-96. PMID 20080970 DOI: 10.1074/Jbc.M109.056747  0.694
2009 Laurie N, Mohan A, McEvoy J, Reed D, Zhang J, Schweers B, Ajioka I, Valentine V, Johnson D, Ellison D, Dyer MA. Changes in retinoblastoma cell adhesion associated with optic nerve invasion. Molecular and Cellular Biology. 29: 6268-82. PMID 19786571 DOI: 10.1128/Mcb.00374-09  0.694
2009 Dyer MA. In their own words: interviews with Cell Cycle. The first knockout mouse model of retinoblastoma. Cell Cycle (Georgetown, Tex.). 8: 2145. PMID 19574732 DOI: 10.4161/CC.8.14.9068  0.328
2009 Dyer MA, Martins R, da Silva Filho M, Muniz JA, Silveira LC, Cepko CL, Finlay BL. Developmental sources of conservation and variation in the evolution of the primate eye. Proceedings of the National Academy of Sciences of the United States of America. 106: 8963-8. PMID 19451636 DOI: 10.1073/Pnas.0901484106  0.738
2009 Cicero SA, Johnson D, Reyntjens S, Frase S, Connell S, Chow LM, Baker SJ, Sorrentino BP, Dyer MA. Cells previously identified as retinal stem cells are pigmented ciliary epithelial cells. Proceedings of the National Academy of Sciences of the United States of America. 106: 6685-90. PMID 19346468 DOI: 10.1073/Pnas.0901596106  0.735
2009 Shih CS, Laurie N, Holzmacher J, Spence Y, Nathwani AC, Davidoff AM, Dyer MA. AAV-mediated local delivery of interferon-beta for the treatment of retinoblastoma in preclinical models. Neuromolecular Medicine. 11: 43-52. PMID 19306089 DOI: 10.1007/s12017-009-8059-0  0.647
2009 Ajioka I, McEvoy J, Nakajima K, Dyer M. The role of the Rb family during mouse retinal development Neuroscience Research. 65. DOI: 10.1016/J.Neures.2009.09.139  0.347
2008 Dyer M. Special issue on retinal development Brain Research. 1192: 1-2. PMID 18261521 DOI: 10.1016/j.brainres.2008.01.001  0.358
2008 Ajioka I, Dyer MA. A new model of tumor susceptibility following tumor suppressor gene inactivation. Cell Cycle (Georgetown, Tex.). 7: 735-40. PMID 18239449 DOI: 10.4161/Cc.7.6.5612  0.445
2008 Martins RA, Zindy F, Donovan S, Zhang J, Pounds S, Wey A, Knoepfler PS, Eisenman RN, Roussel MF, Dyer MA. N-myc coordinates retinal growth with eye size during mouse development. Genes & Development. 22: 179-93. PMID 18198336 DOI: 10.1101/Gad.1608008  0.656
2008 Pounds S, Dyer MA. Statistical analysis of data from retroviral clonal experiments in the developing retina. Brain Research. 1192: 178-85. PMID 17950704 DOI: 10.1016/j.brainres.2007.08.074  0.464
2008 Laurie NA, Dyer MA, Shih CS. Targeting MDM2 and MDMX in retinoblastoma (Current Cancer Drug Targets (2007) 7, 7, (689-695)) Current Cancer Drug Targets. 8: 341. DOI: 10.2174/156800908784533472  0.633
2007 Laurie NA, Shih CS, Schin-Shih C, Dyer MA. Targeting MDM2 and MDMX in retinoblastoma. Current Cancer Drug Targets. 7: 689-95. PMID 18045074 DOI: 10.2174/156800907782418266  0.679
2007 Ajioka I, Martins RA, Bayazitov IT, Donovan S, Johnson DA, Frase S, Cicero SA, Boyd K, Zakharenko SS, Dyer MA. Differentiated horizontal interneurons clonally expand to form metastatic retinoblastoma in mice. Cell. 131: 378-90. PMID 17956737 DOI: 10.1016/J.Cell.2007.09.036  0.764
2007 MacPherson D, Dyer MA. Retinoblastoma: from the two-hit hypothesis to targeted chemotherapy. Cancer Research. 67: 7547-50. PMID 17699756 DOI: 10.1158/0008-5472.CAN-07-0276  0.359
2007 Besson A, Hwang HC, Cicero S, Donovan SL, Gurian-West M, Johnson D, Clurman BE, Dyer MA, Roberts JM. Discovery of an oncogenic activity in p27Kip1 that causes stem cell expansion and a multiple tumor phenotype. Genes & Development. 21: 1731-46. PMID 17626791 DOI: 10.1101/Gad.1556607  0.721
2007 Johnson DA, Zhang J, Frase S, Wilson M, Rodriguez-Galindo C, Dyer MA. Neuronal differentiation and synaptogenesis in retinoblastoma. Cancer Research. 67: 2701-11. PMID 17363591 DOI: 10.1158/0008-5472.CAN-06-3754  0.462
2007 Marine JC, Dyer MA, Jochemsen AG. MDMX: from bench to bedside. Journal of Cell Science. 120: 371-8. PMID 17251377 DOI: 10.1242/jcs.03362  0.357
2006 Donovan SL, Dyer MA. Preparation and square wave electroporation of retinal explant cultures. Nature Protocols. 1: 2710-8. PMID 17406527 DOI: 10.1038/Nprot.2006.454  0.365
2006 Laurie NA, Donovan SL, Shih CS, Zhang J, Mills N, Fuller C, Teunisse A, Lam S, Ramos Y, Mohan A, Johnson D, Wilson M, Rodriguez-Galindo C, Quarto M, Francoz S, ... ... Dyer MA, et al. Inactivation of the p53 pathway in retinoblastoma. Nature. 444: 61-6. PMID 17080083 DOI: 10.1038/Nature05194  0.711
2006 Martins RA, Linden R, Dyer MA. Glutamate regulates retinal progenitors cells proliferation during development. The European Journal of Neuroscience. 24: 969-80. PMID 16925590 DOI: 10.1111/J.1460-9568.2006.04966.X  0.721
2006 Johnson DA, Donovan SL, Dyer MA. Mosaic deletion of Rb arrests rod differentiation and stimulates ectopic synaptogenesis in the mouse retina. The Journal of Comparative Neurology. 498: 112-28. PMID 16856163 DOI: 10.1002/Cne.21059  0.429
2006 Donovan SL, Schweers B, Martins R, Johnson D, Dyer MA. Compensation by tumor suppressor genes during retinal development in mice and humans. Bmc Biology. 4: 14. PMID 16672052 DOI: 10.1186/1741-7007-4-14  0.685
2006 Sun H, Chang Y, Schweers B, Dyer MA, Zhang X, Hayward SW, Goodrich DW. An E2F binding-deficient Rb1 protein partially rescues developmental defects associated with Rb1 nullizygosity. Molecular and Cellular Biology. 26: 1527-37. PMID 16449662 DOI: 10.1128/Mcb.26.4.1527-1537.2006  0.412
2005 Schweers BA, Dyer MA. Perspective: new genetic tools for studying retinal development and disease. Visual Neuroscience. 22: 553-60. PMID 16332265 DOI: 10.1017/S0952523805225026  0.428
2005 Laurie NA, Gray JK, Zhang J, Leggas M, Relling M, Egorin M, Stewart C, Dyer MA. Topotecan combination chemotherapy in two new rodent models of retinoblastoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 11: 7569-78. PMID 16243833 DOI: 10.1158/1078-0432.Ccr-05-0849  0.689
2005 Donovan SL, Dyer MA. Regulation of proliferation during central nervous system development. Seminars in Cell & Developmental Biology. 16: 407-21. PMID 15840449 DOI: 10.1016/J.Semcdb.2005.02.012  0.424
2005 Dyer MA, Bremner R. The search for the retinoblastoma cell of origin. Nature Reviews. Cancer. 5: 91-101. PMID 15685194 DOI: 10.1038/nrc1545  0.442
2004 Dyer MA, Donovan SL, Zhang J, Gray J, Ortiz A, Tenney R, Kong J, Allikmets R, Sohocki MM. Retinal degeneration in Aipl1-deficient mice: a new genetic model of Leber congenital amaurosis. Brain Research. Molecular Brain Research. 132: 208-20. PMID 15582159 DOI: 10.1016/J.Molbrainres.2004.10.011  0.47
2004 Donovan SL, Dyer MA. Developmental defects in Rb-deficient retinae. Vision Research. 44: 3323-33. PMID 15536000 DOI: 10.1016/J.Visres.2004.08.007  0.464
2004 Zhang J, Schweers B, Dyer MA. The first knockout mouse model of retinoblastoma. Cell Cycle (Georgetown, Tex.). 3: 952-9. PMID 15190215 DOI: 10.4161/Cc.3.7.1002  0.336
2004 Dyer MA. Mouse models of childhood cancer of the nervous system. Journal of Clinical Pathology. 57: 561-76. PMID 15166259 DOI: 10.1136/jcp.2003.009910  0.404
2004 Zhang J, Gray J, Wu L, Leone G, Rowan S, Cepko CL, Zhu X, Craft CM, Dyer MA. Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nature Genetics. 36: 351-60. PMID 14991054 DOI: 10.1038/Ng1318  0.766
2004 Baron MH, Willey S, Sahr K, Zhang H, Balbi K, Dyer MA, Adlam M. Induction and Patterning of Pre-Hemato-Vascular Mesoderm by the Mouse Mix Homeodomain Protein. Blood. 104: 565-565. DOI: 10.1182/blood.v104.11.565.565  0.402
2003 Dyer MA. Regulation of proliferation, cell fate specification and differentiation by the homeodomain proteins Prox1, Six3, and Chx10 in the developing retina. Cell Cycle (Georgetown, Tex.). 2: 350-7. PMID 12851489  0.37
2003 Dyer MA, Livesey FJ, Cepko CL, Oliver G. Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nature Genetics. 34: 53-8. PMID 12692551 DOI: 10.1038/ng1144  0.742
2003 Dyer MA. The Homeodomain Proteins Prox1, Six3 and Chx10 Regulate Proliferation, Cell Fate Specification and Differentiation in the Developing Retina Cell Cycle. 2: 347-354. DOI: 10.4161/cc.2.4.429  0.467
2003 Akey DT, Zhu X, Dyer M, Li A, Sorensen A, Fukada-Kamitani T, Daiger SP, Craft C, Kamitani T, Sohocki MM. Functional Studies of AIPL1 Advances in Experimental Medicine and Biology. 533: 287-295. DOI: 10.1007/978-1-4615-0067-4_35  0.323
2002 Akey DT, Zhu X, Dyer M, Li A, Sorensen A, Blackshaw S, Fukuda-Kamitani T, Daiger SP, Craft CM, Kamitani T, Sohocki MM. The inherited blindness associated protein AIPL1 interacts with the cell cycle regulator protein NUB1. Human Molecular Genetics. 11: 2723-33. PMID 12374762 DOI: 10.1093/HMG/11.22.2723  0.631
2001 Dyer MA, Cepko CL. p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4259-71. PMID 11404411 DOI: 10.1523/Jneurosci.21-12-04259.2001  0.6
2001 Dyer MA, Cepko CL. Regulating proliferation during retinal development. Nature Reviews. Neuroscience. 2: 333-42. PMID 11331917 DOI: 10.1038/35072555  0.571
2001 Dyer MA, Cepko CL. The p57Kip2 cyclin kinase inhibitor is expressed by a restricted set of amacrine cells in the rodent retina. The Journal of Comparative Neurology. 429: 601-14. PMID 11135238 DOI: 10.1002/1096-9861(20010122)429:4<601::AID-CNE7>3.0.CO;2-V  0.565
2000 Dyer MA, Cepko CL. Control of Müller glial cell proliferation and activation following retinal injury. Nature Neuroscience. 3: 873-80. PMID 10966617 DOI: 10.1038/78774  0.595
2000 Dyer MA, Cepko CL. p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina. Development (Cambridge, England). 127: 3593-605. PMID 10903183  0.599
Show low-probability matches.