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Martin Y. Pettersson, Ph.D. - Publications

Affiliations: 
2007 Chemistry and Biochemistry University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
Natural Product Synthesis
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18 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Chen JL, Zhang P, Abe M, Aikawa H, Zhang L, Frank AJ, Zembryski T, Hubbs C, Park H, Withka J, Steppan C, Rogers L, Cabral S, Pettersson M, Wager TT, et al. Design, Optimization, and Study of Small Molecules That Target Tau Pre-mRNA and Affect Splicing. Journal of the American Chemical Society. PMID 32364710 DOI: 10.1021/Jacs.0C00768  0.323
2019 Xie L, Ende CWa, Pettersson M, Rankic DA, Sach NW, Sakya S, Humphrey JM. Synthesis of Pyridopyrazine-1,6-dione γ-Secretase Modulators via Selective 4-Methylimidazole N1-Buchwald Arylation. Journal of Organic Chemistry. 84: 4921-4925. PMID 30620601 DOI: 10.1021/Acs.Joc.8B02953  0.413
2017 Pettersson M, Johnson DS, Rankic DA, Kauffman GW, Am Ende CW, Butler TW, Boscoe B, Evrard E, Helal CJ, Humphrey JM, Stepan AF, Stiff CM, Yang E, Xie L, Bales KR, et al. Discovery of cyclopropyl chromane-derived pyridopyrazine-1,6-dione γ-secretase modulators with robust central efficacy. Medchemcomm. 8: 730-743. PMID 30108792 DOI: 10.1039/C6Md00406G  0.393
2017 Mukherjee P, Pettersson M, Dutra JK, Xie L, Am Ende CW. Trifluoromethyl Oxetanes: Synthesis and Evaluation as a tert-Butyl Isostere. Chemmedchem. PMID 28815966 DOI: 10.1002/Cmdc.201700333  0.421
2017 Johnson DS, Li YM, Pettersson M, St George-Hyslop PH. Structural and Chemical Biology of Presenilin Complexes. Cold Spring Harbor Perspectives in Medicine. PMID 28320827 DOI: 10.1101/Cshperspect.A024067  0.322
2015 Pettersson M, Johnson DS, Humphrey JM, Butler TW, Am Ende CW, Fish BA, Green ME, Kauffman GW, Mullins PB, O'Donnell CJ, Stepan AF, Stiff CM, Subramanyam C, Tran TP, Vetelino BC, et al. Design of Pyridopyrazine-1,6-dione γ-Secretase Modulators that Align Potency, MDR Efflux Ratio, and Metabolic Stability. Acs Medicinal Chemistry Letters. 6: 596-601. PMID 26005540 DOI: 10.1021/Acsmedchemlett.5B00070  0.369
2015 Pettersson M, Johnson DS, Humphrey JM, Am Ende CW, Evrard E, Efremov I, Kauffman GW, Stepan AF, Stiff CM, Xie L, Bales KR, Hajos-Korcsok E, Murrey HE, Pustilnik LR, Steyn SJ, et al. Discovery of indole-derived pyridopyrazine-1,6-dione γ-secretase modulators that target presenilin. Bioorganic & Medicinal Chemistry Letters. 25: 908-13. PMID 25582600 DOI: 10.1016/J.Bmcl.2014.12.059  0.436
2014 Bian Z, Marvin CC, Pettersson M, Martin SF. Enantioselective total syntheses of citrinadins a and B. Stereochemical revision of their assigned structures. Journal of the American Chemical Society. 136: 14184-92. PMID 25211501 DOI: 10.1021/Ja5074646  0.581
2014 Pettersson M, Johnson DS, Subramanyam C, Bales KR, am Ende CW, Fish BA, Green ME, Kauffman GW, Mullins PB, Navaratnam T, Sakya SM, Stiff CM, Tran TP, Xie L, Zhang L, et al. Design, synthesis, and pharmacological evaluation of a novel series of pyridopyrazine-1,6-dione γ-secretase modulators. Journal of Medicinal Chemistry. 57: 1046-62. PMID 24428186 DOI: 10.1021/Jm401782H  0.429
2013 Pettersson M, Stepan AF, Kauffman GW, Johnson DS. Novel γ-secretase modulators for the treatment of Alzheimer's disease: a review focusing on patents from 2010 to 2012. Expert Opinion On Therapeutic Patents. 23: 1349-66. PMID 23875696 DOI: 10.1517/13543776.2013.821465  0.309
2013 Pozdnyakov N, Murrey HE, Crump CJ, Pettersson M, Ballard TE, Am Ende CW, Ahn K, Li YM, Bales KR, Johnson DS. γ-Secretase modulator (GSM) photoaffinity probes reveal distinct allosteric binding sites on presenilin. The Journal of Biological Chemistry. 288: 9710-20. PMID 23396974 DOI: 10.1074/Jbc.M112.398602  0.305
2013 Tran TP, Mullins PB, am Ende CW, Pettersson M. Synthesis of pyridopyrazine-1,6-diones from 6-hydroxypicolinic acids via a one-pot coupling/cyclization reaction. Organic Letters. 15: 642-5. PMID 23330785 DOI: 10.1021/Ol303463E  0.344
2012 Pettersson M, Johnson DS, Subramanyam C, Bales KR, am Ende CW, Fish BA, Green ME, Kauffman GW, Lira R, Mullins PB, Navaratnam T, Sakya SM, Stiff CM, Tran TP, Vetelino BC, et al. Design and synthesis of dihydrobenzofuran amides as orally bioavailable, centrally active γ-secretase modulators. Bioorganic & Medicinal Chemistry Letters. 22: 2906-11. PMID 22429469 DOI: 10.1016/J.Bmcl.2012.02.059  0.377
2012 Oborski CE, Iyer R, Maguire BA, Bora G, Atchison K, Pozdnyakov N, Wood K, Parker C, Subashi TA, Pettersson M, Johnson DS, Bales KR. Pharmacological Assessment of γ-Secretase Activity from Rodent and Human Brain Neuroscience and Medicine. 3: 149-161. DOI: 10.4236/Nm.2012.32020  0.326
2011 Pettersson M, Kauffman GW, am Ende CW, Patel NC, Stiff C, Tran TP, Johnson DS. Novel γ-secretase modulators: a review of patents from 2008 to 2010. Expert Opinion On Therapeutic Patents. 21: 205-26. PMID 21231889 DOI: 10.1517/13543776.2011.547479  0.331
2010 Oborski CEJ, Parker C, Pettersson M, Johnson DS, Iyer R, Bales K. Gamma-secretase inhibitors and gamma-secretase modulators differentially regulate amyloid-beta 42 peptide generation in native brain membrane preparations from multiple species Alzheimers & Dementia. 6. DOI: 10.1016/J.Jalz.2010.05.848  0.305
2007 Pettersson M, Knueppel D, Martin SF. Concise, stereoselective approach to the spirooxindole ring system of citrinadin A. Organic Letters. 9: 4623-6. PMID 17918954 DOI: 10.1021/Ol702132V  0.51
2006 Deiters A, Pettersson M, Martin SF. General strategy for the syntheses of corynanthe, tacaman, and oxindole alkaloids. The Journal of Organic Chemistry. 71: 6547-61. PMID 16901143 DOI: 10.1021/Jo061032T  0.594
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