| Year |
Citation |
Score |
| 2014 |
Rettenmaier TJ, Sadowsky JD, Thomsen ND, Chen SC, Doak AK, Arkin MR, Wells JA. A small-molecule mimic of a peptide docking motif inhibits the protein kinase PDK1. Proceedings of the National Academy of Sciences of the United States of America. 111: 18590-5. PMID 25518860 DOI: 10.1073/Pnas.1415365112 |
0.523 |
|
| 2013 |
Wang N, Majmudar CY, Pomerantz WC, Gagnon JK, Sadowsky JD, Meagher JL, Johnson TK, Stuckey JA, Brooks CL, Wells JA, Mapp AK. Ordering a dynamic protein via a small-molecule stabilizer. Journal of the American Chemical Society. 135: 3363-6. PMID 23384013 DOI: 10.1021/Ja3122334 |
0.686 |
|
| 2011 |
Sadowsky JD, Burlingame MA, Wolan DW, McClendon CL, Jacobson MP, Wells JA. Turning a protein kinase on or off from a single allosteric site via disulfide trapping. Proceedings of the National Academy of Sciences of the United States of America. 108: 6056-61. PMID 21430264 DOI: 10.1073/Pnas.1102376108 |
0.364 |
|
| 2010 |
Wells JA, Wolan D, Zorn J, Datta D, Gray D, Sadowsky J. Abstract SY11-03: Turning enzymes on with small molecules Cancer Research. 70. DOI: 10.1158/1538-7445.Am10-Sy11-03 |
0.305 |
|
| 2009 |
Lee EF, Sadowsky JD, Smith BJ, Czabotar PE, Peterson-Kaufman KJ, Colman PM, Gellman SH, Fairlie WD. High-resolution structural characterization of a helical alpha/beta-peptide foldamer bound to the anti-apoptotic protein Bcl-xL. Angewandte Chemie (International Ed. in English). 48: 4318-22. PMID 19229915 DOI: 10.1002/Anie.200805761 |
0.694 |
|
| 2008 |
Boersma MD, Sadowsky JD, Tomita YA, Gellman SH. Hydrophile scanning as a complement to alanine scanning for exploring and manipulating protein-protein recognition: application to the Bim BH3 domain. Protein Science : a Publication of the Protein Society. 17: 1232-40. PMID 18467496 DOI: 10.1110/Ps.032896.107 |
0.715 |
|
| 2008 |
Peterson KJ, Sadowsky JD, Scheef EA, Pal S, Kourentzi KD, Willson RC, Bresnick EH, Sheibani N, Gellman SH. A fluorescence polarization assay for identifying ligands that bind to vascular endothelial growth factor Analytical Biochemistry. 378: 8-14. PMID 18413228 DOI: 10.1016/J.Ab.2008.03.043 |
0.522 |
|
| 2008 |
Murray JK, Sadowsky JD, Scalf M, Smith LM, Tomita Y, Gellman SH. Exploration of structure--activity relationships among foldamer ligands for a specific protein binding site via parallel and split-and-mix library synthesis. Journal of Combinatorial Chemistry. 10: 204-15. PMID 18275161 DOI: 10.1021/Cc700153Z |
0.754 |
|
| 2007 |
Tang L, Hopper ED, Tong Y, Sadowsky JD, Peterson KJ, Gellman SH, Fitzgerald MC. H/D exchange- and mass spectrometry-based strategy for the thermodynamic analysis of protein-ligand binding. Analytical Chemistry. 79: 5869-77. PMID 17580981 DOI: 10.1021/Ac0700777 |
0.566 |
|
| 2007 |
Sadowsky JD, Murray JK, Tomita Y, Gellman SH. Exploration of backbone space in foldamers containing alpha- and beta-amino acid residues: developing protease-resistant oligomers that bind tightly to the BH3-recognition cleft of Bcl-xL. Chembiochem : a European Journal of Chemical Biology. 8: 903-16. PMID 17503422 DOI: 10.1002/Cbic.200600546 |
0.757 |
|
| 2007 |
Sadowsky JD, Fairlie WD, Hadley EB, Lee HS, Umezawa N, Nikolovska-Coleska Z, Wang S, Huang DC, Tomita Y, Gellman SH. (alpha/beta+alpha)-peptide antagonists of BH3 domain/Bcl-x(L) recognition: toward general strategies for foldamer-based inhibition of protein-protein interactions. Journal of the American Chemical Society. 129: 139-54. PMID 17199293 DOI: 10.1021/Ja0662523 |
0.729 |
|
| 2005 |
Murray JK, Farooqi B, Sadowsky JD, Scalf M, Freund WA, Smith LM, Chen J, Gellman SH. Efficient synthesis of a beta-peptide combinatorial library with microwave irradiation. Journal of the American Chemical Society. 127: 13271-80. PMID 16173757 DOI: 10.1021/Ja052733V |
0.704 |
|
| 2005 |
Sadowsky JD, Schmitt MA, Lee HS, Umezawa N, Wang S, Tomita Y, Gellman SH. Chimeric (alpha/beta + alpha)-peptide ligands for the BH3-recognition cleft of Bcl-XL: critical role of the molecular scaffold in protein surface recognition. Journal of the American Chemical Society. 127: 11966-8. PMID 16117535 DOI: 10.1021/Ja053678T |
0.764 |
|
| 2002 |
Jank MM, Sadowsky JD, Peikert C, Berger S. NMR studies on the solution structure of a deletion mutant of the transcarboxylase biotin carrier subunit. International Journal of Biological Macromolecules. 30: 233-42. PMID 12297230 DOI: 10.1016/S0141-8130(02)00033-8 |
0.342 |
|
| 2001 |
Blackwell HE, Sadowsky JD, Howard RJ, Sampson JN, Chao JA, Steinmetz WE, O'Leary DJ, Grubbs RH. Ring-closing metathesis of olefinic peptides: design, synthesis, and structural characterization of macrocyclic helical peptides. The Journal of Organic Chemistry. 66: 5291-302. PMID 11485448 DOI: 10.1021/Jo015533K |
0.446 |
|
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