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Matthias Brewer, Ph.D. - Publications

Affiliations: 
2002 University of Wisconsin, Madison, Madison, WI 
Area:
aspartic protease
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49 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Peck AM, Brewer M. Lewis-Acid-Catalyzed Oxa-Michael Addition to Give α-Diazo-β-alkoxy Carbonyls and Tetrahydro-3-furo[3,4-]pyrazoles. Organic Letters. PMID 37022675 DOI: 10.1021/acs.orglett.3c00723  0.723
2022 Li J, Remington JM, Liao C, Parsons RL, Schneebeli S, Braas KM, May V, Brewer M. GPCR Intracellular Loop Regulation of Beta-Arrestin-Mediated Endosomal Signaling Dynamics. Journal of Molecular Neuroscience : Mn. PMID 35538393 DOI: 10.1007/s12031-022-02016-8  0.619
2020 Fang J, Howard EM, Brewer M. A conjugate addition approach to diazo-containing scaffolds with β quaternary centers. Angewandte Chemie (International Ed. in English). PMID 32365265 DOI: 10.1002/Anie.202004557  0.738
2019 Hensinger MJ, Dodge NJ, Brewer M. Substituted α-Alkylidene Cyclopentenones via the Intramolecular Reaction of Vinyl Cations with Alkenes. Organic Letters. PMID 31873030 DOI: 10.1021/Acs.Orglett.9B04255  0.748
2019 Cleary SE, Hensinger MJ, Qin ZX, Hong X, Brewer M. Migratory Aptitudes in Rearrangements of Destabilized Vinyl Cations. The Journal of Organic Chemistry. PMID 31747287 DOI: 10.1021/Acs.Joc.9B02130  0.736
2019 Liao C, de Molliens MP, Schneebeli ST, Brewer M, Song G, Chatenet D, Braas KM, May V, Li J. Targeting the PAC1 Receptor for Neurological and Metabolic Disorders. Current Topics in Medicinal Chemistry. PMID 31284862 DOI: 10.2174/1568026619666190709092647  0.647
2019 Cleary SE, Li X, Yang LC, Houk KN, Hong X, Brewer M. Reactivity Profiles of Diazo Amides, Esters, and Ketones in Transition-Metal-Free C-H Insertion Reactions. Journal of the American Chemical Society. PMID 30758200 DOI: 10.1021/Jacs.8B12420  0.724
2018 Fang J, Brewer M. Intramolecular Vinylation of Aryl Rings by Vinyl Cations. Organic Letters. PMID 30426753 DOI: 10.1021/Acs.Orglett.8B03054  0.75
2018 Dhakal R, Ivancic M, Brewer M. Two-Step Sequence of Cycloadditions Gives Structurally Complex Tetracyclic 1,2,3,4-Tetrahydrocinnoline Products. The Journal of Organic Chemistry. PMID 29781614 DOI: 10.1021/Acs.Joc.8B00683  0.713
2017 Cleary SE, Hensinger MJ, Brewer M. Remote C-H insertion of vinyl cations leading to cyclopentenones. Chemical Science. 8: 6810-6814. PMID 29147505 DOI: 10.1039/C7Sc02768K  0.735
2017 Liao C, Zhao X, Brewer M, May V, Li J. Conformational Transitions of the Pituitary Adenylate Cyclase-Activating Polypeptide Receptor, a Human Class B GPCR. Scientific Reports. 7: 5427. PMID 28710390 DOI: 10.1038/S41598-017-05815-X  0.653
2017 Al-Bataineh N, Houk KN, Brewer M, Hong X. (2 + 1)-Cycloaddition Reactions Give Further Evidence of the Nitrenium-like Character of 1-Aza-2-azoniaallene Salts. The Journal of Organic Chemistry. PMID 28318256 DOI: 10.1021/Acs.Joc.7B00407  0.73
2016 Dhakal RC, Brewer M. Intramolecular (4 + 2) cycloaddition of aryl-1-aza-2-azoniaallene salts: A practical approach to highly sterically-congested polycyclic protonated azomethine imines. Tetrahedron. 72: 3718-3728. PMID 32071487 DOI: 10.1016/J.Tet.2016.03.037  0.748
2016 Giampa GM, Fang J, Brewer M. A Route to the C,D,E Ring System of the Aspidosperma Alkaloids. Organic Letters. PMID 27500799 DOI: 10.1021/Acs.Orglett.6B01674  0.748
2015 Hong X, Bercovici DA, Yang Z, Al-Bataineh N, Srinivasan R, Dhakal RC, Houk KN, Brewer M. Mechanism and Dynamics of Intramolecular C-H Insertion Reactions of 1-Aza-2-azoniaallene Salts. Journal of the American Chemical Society. 137: 9100-7. PMID 26151292 DOI: 10.1021/Jacs.5B04474  0.732
2015 Collins N, Brewer M. Development of a Clinically Applicable Protocol for Assessment of Hypoxic Response Through Measurement of the Endogenous Gasotransmitter Hydrogen Sulfide in Human Plasma. Journal of Neurosurgical Anesthesiology. 27: 257-61. PMID 25514494 DOI: 10.1097/Ana.0000000000000150  0.637
2015 Hong X, Bercovici DA, Yang Z, Al-Bataineh N, Srinivasan R, Dhakal RC, Houk KN, Brewer M. Mechanism and Dynamics of Intramolecular C-H Insertion Reactions of 1-Aza-2-azoniaallene Salts Journal of the American Chemical Society. 137: 9100-9107. DOI: 10.1021/jacs.5b04474  0.673
2015 Dhakal RC, Brewer M. Intramolecular (4+2) cycloaddition of aryl-1-aza-2-azoniaallene salts: A practical approach to highly sterically-congested polycyclic protonated azomethine imines Tetrahedron. DOI: 10.1016/j.tet.2016.03.037  0.731
2014 Hong X, Liang Y, Brewer M, Houk KN. How tethers control the chemo- and regioselectivities of intramolecular cycloadditions between aryl-1-aza-2-azoniaallenes and alkenes. Organic Letters. 16: 4260-3. PMID 25058856 DOI: 10.1021/Ol501958S  0.717
2014 Bayir A, Brewer M. Fragmentation of bicyclic γ-silyloxy-β-hydroxy-α-diazolactones as an approach to ynolides. The Journal of Organic Chemistry. 79: 6037-46. PMID 24922068 DOI: 10.1021/Jo500634D  0.732
2014 Jabre ND, Watanabe T, Brewer M. Formal and total synthesis of (±)-cycloclavine. Tetrahedron Letters. 56: 197-199. PMID 24511164 DOI: 10.1016/J.Tetlet.2013.10.152  0.709
2014 Bayir A, Brewer M. ChemInform Abstract: Fragmentation of Bicyclic γ-Silyloxy-β-hydroxy-α-diazolactones as an Approach to Ynolides. Cheminform. 45: no-no. DOI: 10.1002/chin.201452175  0.668
2014 Jabre ND, Watanabe T, Brewer M. ChemInform Abstract: Formal and Total Synthesis of (.+-.)-Cycloclavine (I). Cheminform. 45: no-no. DOI: 10.1002/chin.201421229  0.666
2013 Bercovici DA, Ogilvie JM, Tsvetkov N, Brewer M. Intramolecular polar [4(⊕)+2] cycloadditions of aryl-1-aza-2-azoniaallene salts: unprecedented reactivity leading to polycyclic protonated azomethine imines. Angewandte Chemie (International Ed. in English). 52: 13338-41. PMID 24218159 DOI: 10.1002/Anie.201306553  0.747
2013 Zhang Z, Giampa GM, Draghici C, Huang Q, Brewer M. Synthesis of demissidine by a ring fragmentation 1,3-dipolar cycloaddition approach. Organic Letters. 15: 2100-3. PMID 23586838 DOI: 10.1021/Ol4004993  0.739
2013 Al-Bataineh NQ, Brewer M. ChemInform Abstract: Iodine(III)-Mediated Bicyclic Diazenium Salt Formation. Cheminform. 44: no-no. DOI: 10.1002/chin.201302095  0.664
2012 Jabre ND, Brewer M. Stereoelectronic effects in the fragmentation of γ-silyloxy-β-hydroxy-α-diazocarbonyl compounds. The Journal of Organic Chemistry. 77: 9910-4. PMID 23066902 DOI: 10.1021/Jo301944T  0.709
2012 Bercovici DA, Brewer M. Stereospecific intramolecular C-H amination of 1-aza-2-azoniaallene salts. Journal of the American Chemical Society. 134: 9890-3. PMID 22680985 DOI: 10.1021/Ja303054C  0.747
2012 Tsvetkov NP, Bayir A, Schneider S, Brewer M. A ring fragmentation approach to medium-sized cyclic 2-alkynones. Organic Letters. 14: 264-7. PMID 22132946 DOI: 10.1021/Ol2030422  0.721
2012 Al-Bataineh NQ, Brewer M. Iodine(III)-mediated bicyclic diazenium salt formation Tetrahedron Letters. 53: 5411-5413. DOI: 10.1016/J.Tetlet.2012.07.116  0.705
2012 Bercovici DA, Brewer M. ChemInform Abstract: Stereospecific Intramolecular C-H Amination of 1-Aza-2-azoniaallene Salts. Cheminform. 43: no-no. DOI: 10.1002/chin.201245144  0.667
2010 Wyman J, Javed MI, Al-Bataineh N, Brewer M. Synthetic approaches to bicyclic diazenium salts. The Journal of Organic Chemistry. 75: 8078-87. PMID 21067195 DOI: 10.1021/Jo101706H  0.727
2010 Bayir A, Draghici C, Brewer M. Preparation of tethered aldehyde ynoates and ynones by ring fragmentation of cyclic gamma-oxy-beta-hydroxy-alpha-diazo carbonyls. The Journal of Organic Chemistry. 75: 296-302. PMID 20020697 DOI: 10.1021/Jo902405F  0.699
2010 Bayir A, Draghici C, Brewer M. ChemInform Abstract: Preparation of Tethered Aldehyde Ynoates and Ynones by Ring Fragmentation of Cyclic γ-Oxy-β-hydroxy-α-diazo Carbonyls. Cheminform. 41. DOI: 10.1002/chin.201018055  0.706
2009 Draghici C, Huang Q, Brewer M. An efficient synthetic approach to polycyclic 2,5-dihydropyrroles from alpha-silyloxy ketones. The Journal of Organic Chemistry. 74: 8410-3. PMID 19827755 DOI: 10.1021/Jo901978Y  0.716
2009 Javed MI, Wyman JM, Brewer M. Synthesis of fused and bridged bicyclic diazenium salts by intramolecular cycloaddition. Organic Letters. 11: 2189-92. PMID 19371074 DOI: 10.1021/Ol900502S  0.731
2009 Wyman JM, Jochum S, Brewer M. ChemInform Abstract: Chlorodimethylsulfonium Chloride Mediated Formation of Phenyl-α-chloroazoalkanes. Cheminform. 40. DOI: 10.1002/chin.200915066  0.687
2008 Harriman GC, Brewer M, Bennett R, Kuhn C, Bazin M, Larosa G, Skerker P, Cochran N, Gallant D, Baxter D, Picarella D, Jaffee B, Luly JR, Briskin MJ. Selective cell adhesion inhibitors: Barbituric acid based alpha4beta7--MAdCAM inhibitors. Bioorganic & Medicinal Chemistry Letters. 18: 2509-12. PMID 18331794 DOI: 10.1016/j.bmcl.2007.07.068  0.616
2008 Draghici C, Brewer M. Lewis acid promoted carbon-carbon bond cleavage of gamma-silyloxy-beta-hydroxy-alpha-diazoesters. Journal of the American Chemical Society. 130: 3766-7. PMID 18321118 DOI: 10.1021/Ja801004D  0.677
2008 Wyman JM, Jochum S, Brewer M. Chlorodimethylsulfonium chloride-mediated formation of phenyl-α- chloroazoalkanes Synthetic Communications. 38: 3623-3630. DOI: 10.1080/00397910802179961  0.74
2008 Draghici C, Brewer M. ChemInform Abstract: Lewis Acid Promoted Carbon-Carbon Bond Cleavage of γ-Silyloxy-β-hydroxy-α-diazoesters. Cheminform. 39. DOI: 10.1002/chin.200832034  0.663
2007 Javed MI, Brewer M. Diazo preparation via dehydrogenation of hydrazones with "activated" DMSO. Organic Letters. 9: 1789-92. PMID 17408280 DOI: 10.1021/Ol070515W  0.693
2007 Brewer M. Conversion of Hydrazones to Alkyl Chlorides under Swern Oxidation Conditions. Cheminform. 38. DOI: 10.1002/chin.200706047  0.635
2006 Brewer M. Conversion of hydrazones to alkyl chlorides under Swern oxidation conditions Tetrahedron Letters. 47: 7731-7733. DOI: 10.1016/J.Tetlet.2006.08.120  0.692
2005 Haug BE, Brewer M, Rich DH. Facile degradative lactonization of Gln-Arg and Gln-Phe hydroxyethylene dipeptide derivatives. The Journal of Peptide Research : Official Journal of the American Peptide Society. 65: 77-83. PMID 15759328 DOI: 10.1111/J.1399-3011.2004.00208.X  0.492
2004 Brewer M, James CA, Rich DH. Synthesis of a tripeptide derivative containing the gln-arg hydroxyethylene dipeptide isostere. Organic Letters. 6: 4779-82. PMID 15575684 DOI: 10.1021/Ol047880X  0.735
2003 Oost T, Sukonpan C, Brewer M, Goodnough M, Tepp W, Johnson EA, Rich DH. Design and synthesis of substrate-based inhibitors of botulinum neurotoxin type B metalloprotease. Biopolymers. 71: 602-19. PMID 14991672 DOI: 10.1002/Bip.10590  0.751
2002 Brewer M, Oost T, Sukonpan C, Pereckas M, Rich DH. Sequencing hydroxyethylamine-containing peptides via Edman degradation. Organic Letters. 4: 3469-72. PMID 12323046 DOI: 10.1021/Ol026590I  0.732
2001 Brewer M, Rich DH. Synthesis of a tripeptide derivative containing the Phe-Arg hydroxyethylene dipeptide isostere. Organic Letters. 3: 945-8. PMID 11263922 DOI: 10.1021/ol015612i  0.759
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