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Xiaoming Zhan, Ph.D. - Publications

Affiliations: 
2002 University of Texas at Austin, Austin, Texas, U.S.A. 
Area:
discovery and development of protein therapeutics and applied immunology by capitalizing on state of the art protein engineering, directed evolution and systems biology technologies
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38 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 SoRelle JA, Chen Z, Wang J, Yue T, Choi JH, Wang KW, Zhong X, Hildebrand S, Russell J, Scott L, Xu D, Zhan X, Bu CH, Wang T, Choi M, ... ... Zhan X, et al. Dominant atopy risk mutations identified by mouse forward genetic analysis. Allergy. PMID 32810290 DOI: 10.1111/All.14564  0.301
2020 Zhan X, Zhong X, Choi JH, Su L, Wang J, Nair-Gill E, Anderton P, Li X, Tang M, Russell J, Ludwig S, Gallagher T, Beutler B. Adenosine monophosphate deaminase 3 null mutation causes reduction of naive T cells in mouse peripheral blood. Blood Advances. 4: 3594-3605. PMID 32761233 DOI: 10.1182/Bloodadvances.2020001762  0.302
2020 Zhong X, Su L, Yang Y, Nair-Gill E, Tang M, Anderton P, Li X, Wang J, Zhan X, Tomchick DR, Brautigam CA, Moresco EMY, Choi JH, Beutler B. Genetic and structural studies of RABL3 reveal an essential role in lymphoid development and function. Proceedings of the National Academy of Sciences of the United States of America. PMID 32220963 DOI: 10.1073/Pnas.2000703117  0.375
2020 Choi JH, Han J, Theodoropoulos PC, Zhong X, Wang J, Medler D, Ludwig S, Zhan X, Li X, Tang M, Gallagher T, Yu G, Beutler B. Essential requirement for nicastrin in marginal zone and B-1 B cell development. Proceedings of the National Academy of Sciences of the United States of America. PMID 32071239 DOI: 10.1073/Pnas.1916645117  0.36
2020 Choi JH, Zhong X, Zhang Z, Su L, McAlpine W, Misawa T, Liao TC, Zhan X, Russell J, Ludwig S, Li X, Tang M, Anderton P, Moresco EMY, Beutler B. Essential cell-extrinsic requirement for PDIA6 in lymphoid and myeloid development. The Journal of Experimental Medicine. 217. PMID 31985756 DOI: 10.1084/Jem.20190006  0.372
2020 Misawa T, SoRelle JA, Choi JH, Yue T, Wang KW, McAlpine W, Wang J, Liu A, Tabeta K, Turer EE, Evers B, Nair-Gill E, Poddar S, Su L, Ou F, ... ... Zhan X, et al. Mutual inhibition between Prkd2 and Bcl6 controls T follicular helper cell differentiation. Science Immunology. 5. PMID 31980486 DOI: 10.1126/Sciimmunol.Aaz0085  0.317
2019 Zhang D, Yue T, Choi JH, Nair-Gill E, Zhong X, Wang KW, Zhan X, Li X, Choi M, Tang M, Quan J, Hildebrand S, Moresco EMY, Beutler B. Syndromic immune disorder caused by a viable hypomorphic allele of spliceosome component Snrnp40. Nature Immunology. PMID 31427773 DOI: 10.1038/S41590-019-0464-4  0.38
2019 Wang KW, Zhan X, McAlpine W, Zhang Z, Choi JH, Shi H, Misawa T, Yue T, Zhang D, Wang Y, Ludwig S, Russell J, Tang M, Li X, Murray AR, et al. Enhanced susceptibility to chemically induced colitis caused by excessive endosomal TLR signaling in LRBA-deficient mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 31097594 DOI: 10.1073/Pnas.1901407116  0.351
2019 Choi JH, Zhong X, McAlpine W, Liao TC, Zhang D, Fang B, Russell J, Ludwig S, Nair-Gill E, Zhang Z, Wang KW, Misawa T, Zhan X, Choi M, Wang T, et al. LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling. Science (New York, N.Y.). 364. PMID 31073040 DOI: 10.1126/Science.Aau0812  0.365
2019 Zhang Z, Zhan X, Kim B, Wu J. A proteomic approach identifies SAFB-like transcription modulator (SLTM) as a bidirectional regulator of GLI family zinc finger transcription factors. The Journal of Biological Chemistry. PMID 30782847 DOI: 10.1074/Jbc.Ra118.007018  0.374
2018 Turer EE, San Miguel M, Wang KW, McAlpine W, Ou F, Li X, Tang M, Zang Z, Wang J, Hayse B, Evers B, Zhan X, Russell J, Beutler B. A viable hypomorphic mutation causes hyperphagic obesity, diabetes and hepatic steatosis. Disease Models & Mechanisms. 11. PMID 30563851 DOI: 10.1242/Dmm.035451  0.334
2018 McAlpine W, Sun L, Wang KW, Liu A, Jain R, San Miguel M, Wang J, Zhang Z, Hayse B, McAlpine SG, Choi JH, Zhong X, Ludwig S, Russell J, Zhan X, et al. Excessive endosomal TLR signaling causes inflammatory disease in mice with defective SMCR8-WDR41-C9ORF72 complex function. Proceedings of the National Academy of Sciences of the United States of America. PMID 30442666 DOI: 10.1073/Pnas.1814753115  0.319
2018 McAlpine W, Wang KW, Choi JH, San Miguel M, McAlpine SG, Russell J, Ludwig S, Li X, Tang M, Zhan X, Choi M, Wang T, Bu CH, Murray AR, Moresco EMY, et al. The class I myosin MYO1D binds to lipid and protects against colitis. Disease Models & Mechanisms. 11. PMID 30279225 DOI: 10.1242/Dmm.035923  0.305
2018 Wang Y, Su L, Morin MD, Jones BT, Mifune Y, Shi H, Wang KW, Zhan X, Liu A, Wang J, Li X, Tang M, Ludwig S, Hildebrand S, Zhou K, et al. Adjuvant effect of the novel TLR1/TLR2 agonist Diprovocim synergizes with anti-PD-L1 to eliminate melanoma in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 30150374 DOI: 10.1073/Pnas.1809232115  0.304
2017 Sun L, Jiang Z, Acosta-Rodriguez VA, Berger M, Du X, Choi JH, Wang J, Wang KW, Kilaru GK, Mohawk JA, Quan J, Scott L, Hildebrand S, Li X, Tang M, ... Zhan X, et al. HCFC2 is needed for IRF1- and IRF2-dependent Tlr3 transcription and for survival during viral infections. The Journal of Experimental Medicine. PMID 28970238 DOI: 10.1084/Jem.20161630  0.344
2017 Zhang D, Tomisato W, Su L, Sun L, Choi JH, Zhang Z, Wang KW, Zhan X, Choi M, Li X, Tang M, Castro-Perez JM, Hildebrand S, Murray AR, Moresco EMY, et al. Skin-specific regulation of SREBP processing and lipid biosynthesis by glycerol kinase 5. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607088 DOI: 10.1073/Pnas.1705312114  0.32
2017 Choi JH, Wang KW, Zhang D, Zhan X, Wang T, Bu CH, Behrendt CL, Zeng M, Wang Y, Misawa T, Li X, Tang M, Zhan X, Scott L, Hildebrand S, et al. IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137874 DOI: 10.1073/Pnas.1621258114  0.348
2017 Turer E, McAlpine W, Wang KW, Lu T, Li X, Tang M, Zhan X, Wang T, Zhan X, Bu CH, Murray AR, Beutler B. Creatine maintains intestinal homeostasis and protects against colitis. Proceedings of the National Academy of Sciences of the United States of America. PMID 28137860 DOI: 10.1073/Pnas.1621400114  0.33
2016 Zhang Z, Turer E, Li X, Zhan X, Choi M, Tang M, Press A, Smith SR, Divoux A, Moresco EM, Beutler B. Insulin resistance and diabetes caused by genetic or diet-induced KBTBD2 deficiency in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 27708159 DOI: 10.1073/Pnas.1614467113  0.316
2016 Wang Y, Su L, Morin MD, Jones BT, Whitby LR, Surakattula MMRP, Huang H, Shi H, Choi JH, Wang KW, Moresco EMY, Berger M, Zhan X, Zhang H, Boger DL, et al. Erratum: TLR4/MD-2 activation by a synthetic agonist with no similarity to LPS (Proceedings of the National Academy of Sciences of the United States of America (2016) 113 (E884-E893)) Proceedings of the National Academy of Sciences of the United States of America. 113. PMID 27036010 DOI: 10.1073/Pnas.1603716113  0.304
2015 Shi H, Wang Y, Li X, Zhan X, Tang M, Fina M, Su L, Pratt D, Bu CH, Hildebrand S, Lyon S, Scott L, Quan J, Sun Q, Russell J, et al. NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component. Nature Immunology. PMID 26642356 DOI: 10.1038/Ni.3333  0.312
2015 Zhang Z, Cao M, Chang CW, Wang C, Shi X, Zhan X, Birnbaum SG, Bezprozvanny I, Huber K, Wu JI. Autism-Associated Chromatin Regulator Brg1/SmarcA4 is Required for Synapse Development and MEF2-mediated Synapse Remodeling. Molecular and Cellular Biology. PMID 26459759 DOI: 10.1128/Mcb.00534-15  0.307
2015 Siggs OM, Popkin DL, Krebs P, Li X, Tang M, Zhan X, Zeng M, Lin P, Xia Y, Oldstone MB, Cornall RJ, Beutler B. Mutation of the ER retention receptor KDELR1 leads to cell-intrinsic lymphopenia and a failure to control chronic viral infection. Proceedings of the National Academy of Sciences of the United States of America. PMID 26438836 DOI: 10.1073/Pnas.1515619112  0.346
2015 Wang T, Zhan X, Bu CH, Lyon S, Pratt D, Hildebrand S, Choi JH, Zhang Z, Zeng M, Wang KW, Turer E, Chen Z, Zhang D, Yue T, Wang Y, ... ... Zhan X, et al. Real-time resolution of point mutations that cause phenovariance in mice. Proceedings of the National Academy of Sciences of the United States of America. 112: E440-9. PMID 25605905 DOI: 10.1073/Pnas.1423216112  0.323
2014 Zeng M, Hu Z, Shi X, Li X, Zhan X, Li XD, Wang J, Choi JH, Wang KW, Purrington T, Tang M, Fina M, DeBerardinis RJ, Moresco EM, Pedersen G, et al. MAVS, cGAS, and endogenous retroviruses in T-independent B cell responses. Science (New York, N.Y.). 346: 1486-92. PMID 25525240 DOI: 10.1126/Science.346.6216.1486  0.367
2014 Shi X, Zhang Z, Zhan X, Cao M, Satoh T, Akira S, Shpargel K, Magnuson T, Li Q, Wang R, Wang C, Ge K, Wu J. An epigenetic switch induced by Shh signalling regulates gene activation during development and medulloblastoma growth. Nature Communications. 5: 5425. PMID 25370275 DOI: 10.1038/Ncomms6425  0.331
2014 Chen Z, Holland W, Shelton JM, Ali A, Zhan X, Won S, Tomisato W, Liu C, Li X, Moresco EM, Beutler B. Mutation of mouse Samd4 causes leanness, myopathy, uncoupled mitochondrial respiration, and dysregulated mTORC1 signaling. Proceedings of the National Academy of Sciences of the United States of America. 111: 7367-72. PMID 24799716 DOI: 10.1073/Pnas.1406511111  0.366
2011 Zhan X, Shi X, Zhang Z, Chen Y, Wu JI. Dual role of Brg chromatin remodeling factor in Sonic hedgehog signaling during neural development. Proceedings of the National Academy of Sciences of the United States of America. 108: 12758-63. PMID 21768360 DOI: 10.1073/Pnas.1018510108  0.344
2009 Binnerts ME, Tomasevic N, Bright JM, Leung J, Ahn VE, Kim KA, Zhan X, Liu S, Yonkovich S, Williams J, Zhou M, Gros D, Dixon M, Korver W, Weis WI, et al. The first propeller domain of LRP6 regulates sensitivity to DKK1. Molecular Biology of the Cell. 20: 3552-60. PMID 19477926 DOI: 10.1091/Mbc.E08-12-1252  0.311
2008 Kim KA, Wagle M, Tran K, Zhan X, Dixon MA, Liu S, Gros D, Korver W, Yonkovich S, Tomasevic N, Binnerts M, Abo A. R-Spondin family members regulate the Wnt pathway by a common mechanism. Molecular Biology of the Cell. 19: 2588-96. PMID 18400942 DOI: 10.1091/Mbc.E08-02-0187  0.356
2007 Nam JS, Park E, Turcotte TJ, Palencia S, Zhan X, Lee J, Yun K, Funk WD, Yoon JK. Mouse R-spondin2 is required for apical ectodermal ridge maintenance in the hindlimb. Developmental Biology. 311: 124-35. PMID 17904116 DOI: 10.1016/J.Ydbio.2007.08.023  0.327
2007 Binnerts ME, Kim KA, Bright JM, Patel SM, Tran K, Zhou M, Leung JM, Liu Y, Lomas WE, Dixon M, Hazell SA, Wagle M, Nie WS, Tomasevic N, Williams J, ... Zhan X, et al. R-Spondin1 regulates Wnt signaling by inhibiting internalization of LRP6. Proceedings of the National Academy of Sciences of the United States of America. 104: 14700-5. PMID 17804805 DOI: 10.1073/Pnas.0702305104  0.348
2007 Korver W, Singh S, Liu S, Zhao X, Yonkovich S, Sweeney A, Anton K, Lomas WE, Greenwood R, Smith A, Tran DH, Shinkawa P, Jimenez M, Yeung P, Aguilar G, ... ... Zhan X, et al. The lymphoid cell surface receptor NTB-A: a novel monoclonal antibody target for leukaemia and lymphoma therapeutics. British Journal of Haematology. 137: 307-18. PMID 17456053 DOI: 10.1111/J.1365-2141.2007.06569.X  0.304
2006 Gao J, Lee K, Zhao M, Qiu J, Zhan X, Saxena A, Moore CJ, Cohen SN, Georgiou G. Differential modulation of E. coli mRNA abundance by inhibitory proteins that alter the composition of the degradosome Molecular Microbiology. 61: 394-406. PMID 16771842 DOI: 10.1111/J.1365-2958.2006.05246.X  0.64
2004 Zhan X, Gao J, Jain C, Cieslewicz MJ, Swartz JR, Georgiou G. Genetic analysis of disulfide isomerization in Escherichia coli: expression of DsbC is modulated by RNase E-dependent mRNA processing. Journal of Bacteriology. 186: 654-60. PMID 14729690 DOI: 10.1128/Jb.186.3.654-660.2004  0.617
2003 Lee K, Zhan X, Gao J, Qiu J, Feng Y, Meganathan R, Cohen SN, Georgiou G. RraA. a protein inhibitor of RNase E activity that globally modulates RNA abundance in E. coli. Cell. 114: 623-34. PMID 13678585 DOI: 10.1016/J.Cell.2003.08.003  0.641
2003 Lafond R, Zhan X, Georgiou G. Screening and selection strategies for disulfide isomerase activity. Methods in Molecular Biology (Clifton, N.J.). 230: 239-57. PMID 12824588 DOI: 10.1385/1-59259-396-8:239  0.405
1999 Zhan X, Schwaller M, Gilbert HF, Georgiou G. Facilitating the formation of disulfide bonds in the Escherichia coli periplasm via coexpression of yeast protein disulfide isomerase. Biotechnology Progress. 15: 1033-8. PMID 10585186 DOI: 10.1021/Bp990083R  0.505
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