Stafford Lightman - Publications

Affiliations: 
University of Bristol, Bristol, England, United Kingdom 
Area:
HPA axis, stress-related behaviour

42 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Russell G, Kalafatakis K, Durant C, Marchant N, Thakrar J, Thirard R, King J, Bowles J, Upton T, Thai NJ, Brooks JCW, Wilson A, Phillips K, Ferguson S, Grabski M, ... ... Lightman SL, et al. Ultradian hydrocortisone replacement alters neuronal processing, emotional ambiguity, affect and fatigue in adrenal insufficiency: The PULSES trial. Journal of Internal Medicine. PMID 37857352 DOI: 10.1111/joim.13721  0.704
2023 Upton TJ, Zavala E, Methlie P, Kämpe O, Tsagarakis S, Øksnes M, Bensing S, Vassiliadi DA, Grytaas MA, Botusan IR, Ueland G, Berinder K, Simunkova K, Balomenaki M, Margaritopoulos D, ... ... Lightman SL, et al. High-resolution daily profiles of tissue adrenal steroids by portable automated collection. Science Translational Medicine. 15: eadg8464. PMID 37343084 DOI: 10.1126/scitranslmed.adg8464  0.712
2022 Galvis D, Zavala E, Walker JJ, Upton T, Lightman SL, Angelini GD, Evans J, Rogers CA, Phillips K, Gibbison B. Modelling the dynamic interaction of systemic inflammation and the hypothalamic-pituitary-adrenal (HPA) axis during and after cardiac surgery. Journal of the Royal Society, Interface. 19: 20210925. PMID 35472267 DOI: 10.1098/rsif.2021.0925  0.729
2020 Fudulu DP, Angelini GD, Papadopoulou FF, Evans J, Walker-Smith T, Kema I, Van Fassen M, Stoica S, Caputo M, Lightman S, Gibbison B. The Peacock study: feasibility of the dynamic characterisation of the paediatric hypothalamic-pituitary-adrenal function during and after cardiac surgery. Bmc Cardiovascular Disorders. 20: 245. PMID 32450805 DOI: 10.1186/S12872-020-01516-Y  0.339
2019 Russell G, Lightman S. The human stress response. Nature Reviews. Endocrinology. PMID 31249398 DOI: 10.1038/S41574-019-0228-0  0.396
2019 Choudhury S, Lightman S, Meeran K. Improving glucocorticoid replacement profiles in adrenal insufficiency. Clinical Endocrinology. PMID 31017681 DOI: 10.1111/Cen.13999  0.311
2018 Fudulu D, Lightman S, Caputo M, Angelini G. Steroids in paediatric heart surgery: eminence or evidence-based practice? Indian Journal of Thoracic and Cardiovascular Surgery : Official Organ, Association of Thoracic and Cardiovascular Surgeons of India. 34: 483-487. PMID 33060920 DOI: 10.1007/S12055-018-0670-Y  0.308
2018 Fudulu DP, Gibbison B, Upton T, Stoica SC, Caputo M, Lightman S, Angelini GD. Corticosteroids in Pediatric Heart Surgery: Myth or Reality. Frontiers in Pediatrics. 6: 112. PMID 29732365 DOI: 10.3389/Fped.2018.00112  0.712
2016 Oster H, Challet E, Ott V, Arvat E, de Kloet ER, Dijk DJ, Lightman S, Vgontzas A, Van Cauter E. The functional and clinical significance of the 24-h rhythm of circulating glucocorticoids. Endocrine Reviews. er20151080. PMID 27749086 DOI: 10.1210/Er.2015-1080  0.64
2016 Henley D, Lightman S, Carrell R. Cortisol and CBG - Getting cortisol to the right place at the right time. Pharmacology & Therapeutics. PMID 27411675 DOI: 10.1016/J.Pharmthera.2016.06.020  0.303
2014 Lightman S, Terry JR. The importance of dynamic signalling for endocrine regulation and drug development: relevance for glucocorticoid hormones. The Lancet. Diabetes & Endocrinology. 2: 593-9. PMID 24731665 DOI: 10.1016/S2213-8587(13)70182-7  0.332
2014 Gibbison B, Walker J, Russell G, Stevenson K, Kershaw Y, Asimakopoulos G, Angelini G, Lightman S. Cardiac surgery alters the sensitivity of the dynamic interaction between the pituitary and adrenal glands Critical Care. 18: 435. DOI: 10.1186/Cc13625  0.342
2012 Vedhara K, Metcalfe C, Brant H, Crown A, Northstone K, Dawe K, Lightman S, Smith GD. Maternal mood and neuroendocrine programming: effects of time of exposure and sex. Journal of Neuroendocrinology. 24: 999-1011. PMID 22385021 DOI: 10.1111/j.1365-2826.2012.02309.x  0.325
2012 Sarabdjitsingh RA, Conway-Campbell BL, Leggett JD, Waite EJ, Meijer OC, De Kloet ER, Lightman SL. Stress responsiveness varies over the ultradian glucocorticoid cycle in a brain-region-specific manner (Endocrinology (2010) 151 (5369-5379) DOI: 10.1210/en.2010-0832) Endocrinology. 153: 6159. DOI: 10.1210/en.2012-1997  0.738
2011 O'Keane V, Lightman S, Patrick K, Marsh M, Papadopoulos AS, Pawlby S, Seneviratne G, Taylor A, Moore R. Changes in the maternal hypothalamic-pituitary-adrenal axis during the early puerperium may be related to the postpartum 'blues'. Journal of Neuroendocrinology. 23: 1149-55. PMID 22004568 DOI: 10.1111/J.1365-2826.2011.02139.X  0.317
2011 O'Keane V, Lightman S, Marsh M, Pawlby S, Papadopoulos AS, Taylor A, Moore R, Patrick K. Increased pituitary-adrenal activation and shortened gestation in a sample of depressed pregnant women: a pilot study. Journal of Affective Disorders. 130: 300-5. PMID 21093926 DOI: 10.1016/J.Jad.2010.10.004  0.301
2010 Walker JJ, Terry JR, Tsaneva-Atanasova K, Armstrong SP, McArdle CA, Lightman SL. Encoding and decoding mechanisms of pulsatile hormone secretion. Journal of Neuroendocrinology. 22: 1226-38. PMID 21054582 DOI: 10.1111/J.1365-2826.2010.02087.X  0.36
2010 Sarabdjitsingh RA, Conway-Campbell BL, Leggett JD, Waite EJ, Meijer OC, de Kloet ER, Lightman SL. Stress responsiveness varies over the ultradian glucocorticoid cycle in a brain-region-specific manner. Endocrinology. 151: 5369-79. PMID 20861228 DOI: 10.1210/En.2010-0832  0.762
2010 Conway-Campbell BL, Sarabdjitsingh RA, McKenna MA, Pooley JR, Kershaw YM, Meijer OC, De Kloet ER, Lightman SL. Glucocorticoid ultradian rhythmicity directs cyclical gene pulsing of the clock gene period 1 in rat hippocampus. Journal of Neuroendocrinology. 22: 1093-100. PMID 20649850 DOI: 10.1111/J.1365-2826.2010.02051.X  0.742
2010 Juruena MF, Cleare AJ, Papadopoulos AS, Poon L, Lightman S, Pariante CM. The prednisolone suppression test in depression: dose-response and changes with antidepressant treatment. Psychoneuroendocrinology. 35: 1486-91. PMID 20558006 DOI: 10.1016/J.Psyneuen.2010.04.016  0.319
2010 Sarabdjitsingh RA, Spiga F, Oitzl MS, Kershaw Y, Meijer OC, Lightman SL, de Kloet ER. Recovery from disrupted ultradian glucocorticoid rhythmicity reveals a dissociation between hormonal and behavioural stress responsiveness. Journal of Neuroendocrinology. 22: 862-71. PMID 20403086 DOI: 10.1111/J.1365-2826.2010.02004.X  0.758
2010 Brant H, Wetherell MA, Lightman S, Crown A, Vedhara K. An exploration into physiological and self-report measures of stress in pre-registration doctors at the beginning and end of a clinical rotation. Stress (Amsterdam, Netherlands). 13: 155-62. PMID 19929317 DOI: 10.3109/10253890903093778  0.325
2009 Evuarherhe O, Leggett J, Waite E, Kershaw Y, Lightman S. Reversal of the hypothalamo-pituitary-adrenal response to oestrogens around puberty. The Journal of Endocrinology. 202: 279-85. PMID 19474059 DOI: 10.1677/Joe-09-0175  0.378
2009 Juruena MF, Pariante CM, Papadopoulos AS, Poon L, Lightman S, Cleare AJ. Prednisolone suppression test in depression: prospective study of the role of HPA axis dysfunction in treatment resistance. The British Journal of Psychiatry : the Journal of Mental Science. 194: 342-9. PMID 19336786 DOI: 10.1192/Bjp.Bp.108.050278  0.302
2009 Shufflebotham J, Wetherell MA, Hince D, Hood S, Lightman S, Nutt D, Probert C, Potokar J. Women with diarrhoea-predominant irritable bowel syndrome show an increased pressure response to 35% carbon dioxide stress challenge. Stress (Amsterdam, Netherlands). 12: 30-6. PMID 18609306 DOI: 10.1080/10253890801976926  0.332
2008 Chen J, Young S, Subburaju S, Sheppard J, Kiss A, Atkinson H, Wood S, Lightman S, Serradeil-Le Gal C, Aguilera G. Vasopressin does not mediate hypersensitivity of the hypothalamic pituitary adrenal axis during chronic stress. Annals of the New York Academy of Sciences. 1148: 349-59. PMID 19120128 DOI: 10.1196/Annals.1410.037  0.382
2007 Conway-Campbell BL, McKenna MA, Wiles CC, Atkinson HC, de Kloet ER, Lightman SL. Proteasome-dependent down-regulation of activated nuclear hippocampal glucocorticoid receptors determines dynamic responses to corticosterone. Endocrinology. 148: 5470-7. PMID 17690167 DOI: 10.1210/en.2007-0585  0.613
2006 Uney JB, Lightman SL. MicroRNAs and osmotic regulation. Proceedings of the National Academy of Sciences of the United States of America. 103: 15278-9. PMID 17030813 DOI: 10.1073/Pnas.0607655103  0.52
2006 Herbert J, Goodyer IM, Grossman AB, Hastings MH, de Kloet ER, Lightman SL, Lupien SJ, Roozendaal B, Seckl JR. Do corticosteroids damage the brain? Journal of Neuroendocrinology. 18: 393-411. PMID 16684130 DOI: 10.1111/J.1365-2826.2006.01429.X  0.572
2005 Bowe JE, Li XF, Kinsey-Jones JS, Paterson S, Brain SD, Lightman SL, O'Byrne KT. Calcitonin gene-related peptide-induced suppression of luteinizing hormone pulses in the rat: the role of endogenous opioid peptides. The Journal of Physiology. 566: 921-8. PMID 15905218 DOI: 10.1113/Jphysiol.2005.085662  0.329
2004 Kaye J, Soothill P, Hunt M, Lightman S. Responses to the 35% CO challenge in postpartum women. Clinical Endocrinology. 61: 582-8. PMID 15521960 DOI: 10.1111/J.1365-2265.2004.02133.X  0.344
2004 Pariante CM, Papadopoulos AS, Poon L, Cleare AJ, Checkley SA, English J, Kerwin RW, Lightman S. Four days of citalopram increase suppression of cortisol secretion by prednisolone in healthy volunteers. Psychopharmacology. 177: 200-6. PMID 15179544 DOI: 10.1007/S00213-004-1925-4  0.324
2003 Vedhara K, Miles J, Bennett P, Plummer S, Tallon D, Brooks E, Gale L, Munnoch K, Schreiber-Kounine C, Fowler C, Lightman S, Sammon A, Rayter Z, Farndon J. An investigation into the relationship between salivary cortisol, stress, anxiety and depression. Biological Psychology. 62: 89-96. PMID 12581685 DOI: 10.1016/S0301-0511(02)00128-X  0.315
2000 Adams EF, Law H, Buchfelder M, Fahlbusch R, Lightman S, Levy A. Presence of GHRH mRNA in human pituitary somatotrophinomas and its relationship to in vitro effect of a GHRH-antagonist on GH secretion and cAMP production. Pituitary. 1: 7-12. PMID 11081178 DOI: 10.1023/A:1009917306289  0.302
2000 Vedhara K, Shanks N, Anderson S, Lightman S. The role of stressors and psychosocial variables in the stress process: A study of chronic caregiver stress Psychosomatic Medicine. 62: 374-385. PMID 10845351 DOI: 10.1097/00006842-200005000-00011  0.321
1999 Geddes BJ, Harding TC, Lightman SL, Uney JB. Assessing viral gene therapy in neuroendocrine models. Frontiers in Neuroendocrinology. 20: 296-316. PMID 10569280 DOI: 10.1006/Frne.1999.0184  0.542
1997 Geddes BJ, Harding TC, Lightman SL, Uney JB. Long-term gene therapy in the CNS: reversal of hypothalamic diabetes insipidus in the Brattleboro rat by using an adenovirus expressing arginine vasopressin. Nature Medicine. 3: 1402-4. PMID 9396613 DOI: 10.1038/Nm1297-1402  0.543
1997 Nicot A, Rowe WB, De Kloet ER, Betancur C, Jessop DS, Lightman SL, Quirion R, Rostène W, Bérod A. Endogenous neurotensin regulates hypothalamic-pituitary-adrenal axis activity and peptidergic neurons in the rat hypothalamic paraventricular nucleus. Journal of Neuroendocrinology. 9: 263-9. PMID 9147289 DOI: 10.1046/J.1365-2826.1997.00581.X  0.62
1997 Ingram C, Windle R, Gamble L, Wood S, Herlihy Y, Shanks N, Lightman S. Oxytocin: a modulator of the endocrine and behavioural responses to stress Behavioural Pharmacology. 8: 651. DOI: 10.1097/00008877-199711000-00044  0.33
1996 Geddes BJ, Harding TC, Hughes DS, Byrnes AP, Lightman SL, Conde G, Uney JB. Persistent transgene expression in the hypothalamus following stereotaxic delivery of a recombinant adenovirus: suppression of the immune response with cyclosporin. Endocrinology. 137: 5166-9. PMID 8895393 DOI: 10.1210/Endo.137.11.8895393  0.537
1995 Baker B, Levy A, Hall L, Lightman S. Cloning and expression of melanin-concentrating hormone genes in the rainbow trout brain. Neuroendocrinology. 61: 67-76. PMID 7731499 DOI: 10.1159/000126814  0.315
1994 Mullens L, Marriott DR, Young KA, Tannahill L, Lightman SL, Wilkin GP. Up-regulation of lipocortin-1 and its mRNA in reactive astrocytes in kainate-lesioned rat cerebellum. Journal of Neuroimmunology. 50: 25-33. PMID 8300854 DOI: 10.1016/0165-5728(94)90211-9  0.539
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