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Agneta Simionescu - Publications

Affiliations: 
Bioengineering Clemson University, Clemson, SC, United States 
Area:
Biomedical Engineering
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36 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Filippi A, Constantin A, Alexandru N, Mocanu CA, Vlad ML, Fenyo IM, Simionescu A, Simionescu DT, Manduteanu I, Georgescu A. VLA4-Enhanced Allogeneic Endothelial Progenitor Cell-Based Therapy Preserves the Aortic Valve Function in a Mouse Model of Dyslipidemia and Diabetes. Pharmaceutics. 14. PMID 35631662 DOI: 10.3390/pharmaceutics14051077  0.349
2021 Manduteanu I, Simionescu D, Simionescu A, Simionescu M. Aortic valve disease in diabetes: Molecular mechanisms and novel therapies. Journal of Cellular and Molecular Medicine. PMID 34561944 DOI: 10.1111/jcmm.16937  0.357
2021 Movileanu I, Harpa M, Al Hussein H, Harceaga L, Chertes A, Al Hussein H, Lutter G, Puehler T, Preda T, Sircuta C, Cotoi O, Nistor D, Man A, Cordos B, Deac R, ... ... Simionescu A, et al. Preclinical Testing of Living Tissue-Engineered Heart Valves for Pediatric Patients, Challenges and Opportunities. Frontiers in Cardiovascular Medicine. 8: 707892. PMID 34490371 DOI: 10.3389/fcvm.2021.707892  0.385
2020 Filippi A, Constantin A, Alexandru N, Voicu G, Constantinescu CA, Rebleanu D, Fenyo M, Simionescu D, Simionescu A, Manduteanu I, Georgescu A. Integrins α4β1 and αVβ3 are Reduced in Endothelial Progenitor Cells from Diabetic Dyslipidemic Mice and May Represent New Targets for Therapy in Aortic Valve Disease. Cell Transplantation. 29: 963689720946277. PMID 32841051 DOI: 10.1177/0963689720946277  0.433
2019 Tucureanu MM, Filippi A, Alexandru N, Ana Constantinescu C, Ciortan L, Macarie R, Vadana M, Voicu G, Frunza S, Nistor D, Simionescu A, Simionescu DT, Georgescu A, Manduteanu I. Diabetes-induced early molecular and functional changes in aortic heart valves in a murine model of atherosclerosis. Diabetes & Vascular Disease Research. 1479164119874469. PMID 31530180 DOI: 10.1177/1479164119874469  0.435
2019 Simionescu DT, Harpa M, Deac R, Suciu H, Gurzu S, Harceaga L, Husssein HA, Preda T, Movileanu I, Harpa L, Moldovan O, Pavai Z, Egyed I, Sircuta C, Nistor D, ... ... Simionescu A, et al. Heart valve tissue engineering using adult stem cells and tissue-derived extracellular matrix scaffolds; in vitro and in vivo studies (VALVE-REGEN) F1000research. 8. DOI: 10.7490/F1000Research.1116741.1  0.451
2018 Dhulekar J, Simionescu A. Challenges in vascular tissue engineering for diabetic patients. Acta Biomaterialia. PMID 29396167 DOI: 10.1016/J.Actbio.2018.01.008  0.501
2016 Harpa M, Movileanu I, Sierad L, Cotoi O, Suciu H, Preda T, Nistor D, Sircuta C, Brânzaniuc K, Deac R, Gurzu S, Harceaga L, Olah P, Simionescu D, Dandel M, ... Simionescu A, et al. In Vivo Testing of Xenogeneic Acellular Aortic Valves Seeded with Stem Cells. Revista Romana De Medicina De Laborator. 24: 343-346. PMID 31098341 DOI: 10.1515/Rrlm-2016-0031  0.358
2016 Chow JP, Simionescu DT, Carter AL, Simionescu A. Immunomodulatory effects of adipose tissue-derived stem cells on elastin scaffold remodeling in diabetes. Tissue Engineering and Regenerative Medicine. 13: 701-712. PMID 30603451 DOI: 10.1007/S13770-016-0018-X  0.665
2016 Kennamer A, Sierad L, Pascal R, Rierson N, Albers C, Harpa M, Cotoi O, Harceaga L, Olah P, Terezia P, Simionescu A, Simionescu D. Bioreactor Conditioning of Valve Scaffolds Seeded Internally with Adult Stem Cells. Tissue Engineering and Regenerative Medicine. 13: 507-515. PMID 30337944 DOI: 10.1007/S13770-016-9114-1  0.392
2016 Deborde C, Simionescu DT, Wright C, Liao J, Sierad LN, Simionescu A. Stabilized collagen and elastin-based scaffolds for mitral valve tissue engineering. Tissue Engineering. Part A. PMID 27608885 DOI: 10.1089/ten.TEA.2016.0032  0.385
2015 Sierad LN, Shaw EL, Bina A, Brazile B, Rierson N, Patnaik SS, Kennamer A, Odum R, Cotoi O, Terezia P, Branzaniuc K, Smallwood H, Deac R, Egyed I, Pavai Z, ... ... Simionescu A, et al. Functional Heart Valve Scaffolds Obtained by Complete Decellularization of Porcine Aortic Roots in a Novel Differential Pressure Gradient Perfusion System. Tissue Engineering. Part C, Methods. PMID 26467108 DOI: 10.1089/Ten.Tec.2015.0170  0.408
2015 Harpa MM, Movileanu I, Sierad LN, Cotoi OS, Suciu H, Sircuta C, Preda T, Nistor D, Branzaniuc K, Deac R, Dandel M, Gurzu S, Harceaga L, Olah P, Simionescu A, et al. Pulmonary heart valve replacement using stabilized acellular xenogeneic scaffolds; effects of seeding with autologous stem cells Revista Romana De Medicina De Laborator. 23: 415-430. DOI: 10.1515/Rrlm-2015-0046  0.418
2014 Pennel T, Fercana G, Bezuidenhout D, Simionescu A, Chuang TH, Zilla P, Simionescu D. The performance of cross-linked acellular arterial scaffolds as vascular grafts; pre-clinical testing in direct and isolation loop circulatory models Biomaterials. 35: 6311-6322. PMID 24816365 DOI: 10.1016/J.Biomaterials.2014.04.062  0.368
2014 Mattix BM, Olsen TR, Casco M, Reese L, Poole JT, Zhang J, Visconti RP, Simionescu A, Simionescu DT, Alexis F. Janus magnetic cellular spheroids for vascular tissue engineering. Biomaterials. 35: 949-60. PMID 24183699 DOI: 10.1016/J.Biomaterials.2013.10.036  0.328
2013 Schulte JB, Simionescu A, Simionescu DT. The acellular myocardial flap: a novel extracellular matrix scaffold enriched with patent microvascular networks and biocompatible cell niches. Tissue Engineering. Part C, Methods. 19: 518-30. PMID 23151037 DOI: 10.1089/Ten.Tec.2012.0536  0.405
2013 Chow JP, Simionescu DT, Warner H, Wang B, Patnaik SS, Liao J, Simionescu A. Mitigation of diabetes-related complications in implanted collagen and elastin scaffolds using matrix-binding polyphenol. Biomaterials. 34: 685-95. PMID 23103157 DOI: 10.1016/J.Biomaterials.2012.09.081  0.659
2013 Larrew T, Chow J, Schulte J, Simionescu D, Simionescu A. The roles of various metabolic enzymes in diabetic cardiomyopathy—in vivo and in vitro approach Cardiovascular Pathology. 22: e48. DOI: 10.1016/J.Carpath.2013.01.067  0.6
2011 Simionescu A, Tedder ME, Chuang TH, Simionescu DT. Lectin and antibody-based histochemical techniques for cardiovascular tissue engineering. Journal of Histotechnology. 34: 20-28. PMID 25620822 DOI: 10.1179/014788811X12949268296040  0.442
2011 Simionescu A, Schulte JB, Fercana G, Simionescu DT. Inflammation in cardiovascular tissue engineering: the challenge to a promise: a minireview. International Journal of Inflammation. 2011: 958247. PMID 21755031 DOI: 10.4061/2011/958247  0.445
2011 Tedder ME, Simionescu A, Chen J, Liao J, Simionescu DT. Assembly and testing of stem cell-seeded layered collagen constructs for heart valve tissue engineering. Tissue Engineering. Part A. 17: 25-36. PMID 20673028 DOI: 10.1089/Ten.Tea.2010.0138  0.457
2010 Sierad LN, Simionescu A, Albers C, Chen J, Maivelett J, Tedder ME, Liao J, Simionescu DT. Design and Testing of a Pulsatile Conditioning System for Dynamic Endothelialization of Polyphenol-Stabilized Tissue Engineered Heart Valves. Cardiovascular Engineering and Technology. 1: 138-153. PMID 21340043 DOI: 10.1007/S13239-010-0014-6  0.465
2009 Chuang TH, Stabler C, Simionescu A, Simionescu DT. Polyphenol-stabilized tubular elastin scaffolds for tissue engineered vascular grafts. Tissue Engineering. Part A. 15: 2837-51. PMID 19254115 DOI: 10.1089/Ten.Tea.2008.0394  0.445
2009 Tedder ME, Liao J, Weed B, Stabler C, Zhang H, Simionescu A, Simionescu DT. Stabilized collagen scaffolds for heart valve tissue engineering. Tissue Engineering. Part A. 15: 1257-68. PMID 18928400 DOI: 10.1089/Ten.Tea.2008.0263  0.476
2007 Simionescu A, Simionescu DT, Vyavahare NR. Osteogenic responses in fibroblasts activated by elastin degradation products and transforming growth factor-beta1: role of myofibroblasts in vascular calcification. The American Journal of Pathology. 171: 116-23. PMID 17591959 DOI: 10.2353/Ajpath.2007.060930  0.333
2006 Lee JS, Basalyga DM, Simionescu A, Isenburg JC, Simionescu DT, Vyavahare NR. Elastin calcification in the rat subdermal model is accompanied by up-regulation of degradative and osteogenic cellular responses. The American Journal of Pathology. 168: 490-8. PMID 16436663 DOI: 10.2353/Ajpath.2006.050338  0.391
2005 Lu Q, Simionescu A, Vyavahare N. Novel capillary channel fiber scaffolds for guided tissue engineering. Acta Biomaterialia. 1: 607-14. PMID 16701841 DOI: 10.1016/J.Actbio.2005.07.001  0.39
2005 Simionescu A, Philips K, Vyavahare N. Elastin-derived peptides and TGF-beta1 induce osteogenic responses in smooth muscle cells. Biochemical and Biophysical Research Communications. 334: 524-32. PMID 16005428 DOI: 10.1016/J.Bbrc.2005.06.119  0.32
2001 Bracher M, Simionescu D, Simionescu A, Davies N, Human P, Zilla P. Matrix metalloproteinases and tissue valve degeneration Journal of Long-Term Effects of Medical Implants. 11: 221-230. PMID 11921665 DOI: 10.1615/Jlongtermeffmedimplants.V11.I34.90  0.38
1997 Simionescu A, Simionescu D, Deac R. MODULATION OF COLLAGENASES AND THE BIOCOMPATIBILITY OF PERICARDIAL-DERIVED HEART VALVES Asaio Journal. 43: 28. DOI: 10.1097/00002480-199703000-00098  0.32
1996 Simionescu A, Simionescu D, Deac R. Biochemical pathways of tissue degeneration in bioprosthetic cardiac valves: The role of matrix metalloproteinases Asaio Journal. 42. PMID 8944942 DOI: 10.1097/00002480-199609000-00049  0.399
1996 Simionescu A, Simionescu DT, Deac RFP. Matrix metalloproteinases in the pathology of natural and bioprosthetic cardiac valves Cardiovascular Pathology. 5: 323-332. DOI: 10.1016/S1054-8807(96)00043-9  0.403
1994 Simionescu DT, Deac R, Simionescu A. Inhibition of extracellular-matrix degrading proteases in pericardial-derived cardiovascular bioprostheses Journal of Materials Science: Materials in Medicine. 5: 748-751. DOI: 10.1007/Bf00120369  0.357
1993 Simionescu D, Simionescu A, Deac R. Detection of remnant proteolytic activities in unimplanted glutaraldehyde- treated bovine pericardium and explanted cardiac bioprostheses Journal of Biomedical Materials Research. 27: 821-829. PMID 8408112 DOI: 10.1002/Jbm.820270615  0.312
1993 Simionescu D, Simionescu A, Deac R. Mapping of glutaraldehyde-treated bovine pericardium and tissue selection for bioprosthetic heart valves Journal of Biomedical Materials Research. 27: 697-704. PMID 8408100 DOI: 10.1002/Jbm.820270602  0.304
1991 Simionescu A, Simionescu D, Deac R. Lysine-enhanced glutaraldehyde crosslinking of collagenous biomaterials Journal of Biomedical Materials Research. 25: 1495-1506. PMID 1794997 DOI: 10.1002/Jbm.820251207  0.332
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