Terry P. Hughes - Publications

Affiliations: 
James Cook University 

283 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Dietzel A, Connolly SR, Hughes TP, Bode M. The spatial footprint and patchiness of large-scale disturbances on coral reefs. Global Change Biology. PMID 34390297 DOI: 10.1111/gcb.15805  1
2021 Duarte CM, Agusti S, Barbier E, Britten GL, Castilla JC, Gattuso JP, Fulweiler RW, Hughes TP, Knowlton N, Lovelock CE, Lotze HK, Predragovic M, Poloczanska E, Roberts C, Worm B. Author Correction: Rebuilding marine life. Nature. PMID 33864053 DOI: 10.1038/s41586-021-03271-2  0.01
2021 Dietzel A, Bode M, Connolly SR, Hughes TP. Author Correction: The population sizes and global extinction risk of reef-building coral species at biogeographic scales. Nature Ecology & Evolution. PMID 33727683 DOI: 10.1038/s41559-021-01441-z  1
2021 Dietzel A, Bode M, Connolly SR, Hughes TP. The population sizes and global extinction risk of reef-building coral species at biogeographic scales. Nature Ecology & Evolution. PMID 33649542 DOI: 10.1038/s41559-021-01393-4  1
2020 Polasky S, Crépin AS, Biggs RO, Carpenter SR, Folke C, Peterson G, Scheffer M, Barrett S, Daily G, Ehrlich P, Howarth RB, Hughes T, Levin SA, Shogren JF, Troell M, et al. Corridors of Clarity: Four Principles to Overcome Uncertainty Paralysis in the Anthropocene. Bioscience. 70: 1139-1144. PMID 33376456 DOI: 10.1093/biosci/biaa115  1
2020 Dietzel A, Bode M, Connolly SR, Hughes TP. Long-term shifts in the colony size structure of coral populations along the Great Barrier Reef. Proceedings. Biological Sciences. 287: 20201432. PMID 33049171 DOI: 10.1098/rspb.2020.1432  1
2020 Duarte CM, Agusti S, Barbier E, Britten GL, Castilla JC, Gattuso JP, Fulweiler RW, Hughes TP, Knowlton N, Lovelock CE, Lotze HK, Predragovic M, Poloczanska E, Roberts C, Worm B. Rebuilding marine life. Nature. 580: 39-51. PMID 32238939 DOI: 10.1038/S41586-020-2146-7  0.01
2020 Turner MG, Calder WJ, Cumming GS, Hughes TP, Jentsch A, LaDeau SL, Lenton TM, Shuman BN, Turetsky MR, Ratajczak Z, Williams JW, Williams AP, Carpenter SR. Climate change, ecosystems and abrupt change: science priorities. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 375: 20190105. PMID 31983326 DOI: 10.1098/Rstb.2019.0105  1
2020 McWilliam M, Pratchett MS, Hoogenboom MO, Hughes TP. Deficits in functional trait diversity following recovery on coral reefs. Proceedings. Biological Sciences. 287: 20192628. PMID 31910784 DOI: 10.1098/Rspb.2019.2628  1
2019 Morrison TH, Hughes TP, Adger WN, Brown K, Barnett J, Lemos MC. Save reefs to rescue all ecosystems. Nature. 573: 333-336. PMID 31534250 DOI: 10.1038/D41586-019-02737-8  1
2019 Kim SW, Sampayo EM, Sommer B, Sims CA, Gómez-Cabrera MDC, Dalton SJ, Beger M, Malcolm HA, Ferrari R, Fraser N, Figueira WF, Smith SDA, Heron SF, Baird AH, Byrne M, ... ... Hughes TP, et al. Refugia under threat: Mass bleaching of coral assemblages in high-latitude eastern Australia. Global Change Biology. PMID 31472029 DOI: 10.1111/Gcb.14772  1
2019 Hughes TP, Kerry JT, Baird AH, Connolly SR, Chase TJ, Dietzel A, Hill T, Hoey AS, Hoogenboom MO, Jacobson M, Kerswell A, Madin JS, Mieog A, Paley AS, Pratchett MS, et al. Global warming impairs stock-recruitment dynamics of corals. Nature. PMID 30944475 DOI: 10.1038/S41586-019-1081-Y  1
2018 Hughes TP, Kerry JT, Baird AH, Connolly SR, Dietzel A, Eakin CM, Heron SF, Hoey AS, Hoogenboom MO, Liu G, McWilliam MJ, Pears RJ, Pratchett MS, Skirving WJ, Stella JS, et al. Global warming transforms coral reef assemblages. Nature. PMID 29670282 DOI: 10.1038/S41586-018-0041-2  1
2018 Lough JM, Anderson KD, Hughes TP. Increasing thermal stress for tropical coral reefs: 1871-2017. Scientific Reports. 8: 6079. PMID 29666437 DOI: 10.1038/S41598-018-24530-9  0.01
2018 McWilliam M, Hoogenboom MO, Baird AH, Kuo CY, Madin JS, Hughes TP. Biogeographical disparity in the functional diversity and redundancy of corals. Proceedings of the National Academy of Sciences of the United States of America. PMID 29507193 DOI: 10.1073/Pnas.1716643115  1
2018 Hughes TP, Anderson KD, Connolly SR, Heron SF, Kerry JT, Lough JM, Baird AH, Baum JK, Berumen ML, Bridge TC, Claar DC, Eakin CM, Gilmour JP, Graham NAJ, Harrison H, et al. Spatial and temporal patterns of mass bleaching of corals in the Anthropocene. Science (New York, N.Y.). 359: 80-83. PMID 29302011 DOI: 10.1126/Science.Aan8048  1
2017 Hughes TP, Kerry JT, Simpson T. Large-scale bleaching of corals on the Great Barrier Reef. Ecology. PMID 29155453 DOI: 10.1002/Ecy.2092  0.01
2017 Hughes TP, Barnes ML, Bellwood DR, Cinner JE, Cumming GS, Jackson JBC, Kleypas J, van de Leemput IA, Lough JM, Morrison TH, Palumbi SR, van Nes EH, Scheffer M. Coral reefs in the Anthropocene. Nature. 546: 82-90. PMID 28569801 DOI: 10.1038/Nature22901  1
2017 Hughes TP, Kerry JT, Álvarez-Noriega M, Álvarez-Romero JG, Anderson KD, Baird AH, Babcock RC, Beger M, Bellwood DR, Berkelmans R, Bridge TC, Butler IR, Byrne M, Cantin NE, Comeau S, et al. Global warming and recurrent mass bleaching of corals. Nature. 543: 373-377. PMID 28300113 DOI: 10.1038/Nature21707  1
2017 Connolly SR, Hughes TP, Bellwood DR. A unified model explains commonness and rarity on coral reefs. Ecology Letters. PMID 28251798 DOI: 10.1111/Ele.12751  1
2017 Cumming GS, Morrison TH, Hughes TP. New Directions for Understanding the Spatial Resilience of Social-Ecological Systems Ecosystems. 20: 649-664. DOI: 10.1007/S10021-016-0089-5  1
2016 Hughes TP, Cameron DS, Chin A, Connolly SR, Day JC, Jones GP, McCook L, McGinnity P, Mumby PJ, Pears RJ, Pressey RL, Russ GR, Tanzer J, Tobin A, Young MA. A critique of claims for negative impacts of Marine Protected Areas on fisheries. Ecological Applications : a Publication of the Ecological Society of America. 26: 637-41. PMID 27209801 DOI: 10.1890/15-0457  1
2016 Mouillot D, Parravicini V, Bellwood DR, Leprieur F, Huang D, Cowman PF, Albouy C, Hughes TP, Thuiller W, Guilhaumon F. Global marine protected areas do not secure the evolutionary history of tropical corals and fishes. Nature Communications. 7: 10359. PMID 26756609 DOI: 10.1038/Ncomms10359  1
2016 Zhang K, Dearing JA, Tong SL, Hughes TP. China's Degraded Environment Enters A New Normal. Trends in Ecology & Evolution. PMID 26753784 DOI: 10.1016/J.Tree.2015.12.002  1
2015 le Coutre PD, Hughes TP, Mahon FX, Kim DW, Steegmann JL, Shah NP, Gooden K, Wallis N, Cortes JE. Low incidence of peripheral arterial disease in patients receiving dasatinib in clinical trials. Leukemia. PMID 26686247 DOI: 10.1038/Leu.2015.352  1
2015 Deininger MW, Hodgson JG, Shah NP, Cortes JE, Kim DW, Nicolini FE, Talpaz M, Baccarani M, Müller MC, Li J, Parker WT, Lustgarten S, Clackson T, Haluska FG, Guilhot F, ... ... Hughes TP, et al. Compound mutations in BCR-ABL1 are not major drivers of primary or secondary resistance to ponatinib in CP-CML patients. Blood. PMID 26603839 DOI: 10.1182/Blood-2015-08-660977  1
2015 Yeung DT, Tang C, Vidovic L, White DL, Branford S, Hughes TP, Yong AS. KIR2DL5B genotype predicts outcomes in CML patients treated with response directed sequential imatinib / nilotinib strategy. Blood. PMID 26500342 DOI: 10.1182/blood-2015-07-655589  1
2015 White DL, Hughes TP. Living with CML: is death no longer the end (point)? Blood. 126: 2-4. PMID 26138535 DOI: 10.1182/blood-2015-05-644732  1
2015 Ong J, Yeung D, Filshie R, Hughes TP, Nandurkar H. Imatinib-induced gastric antral vascular ectasia in three patients with chronic myeloid leukaemia. International Journal of Hematology. 102: 639-42. PMID 26134364 DOI: 10.1007/s12185-015-1824-y  1
2015 Watkins DB, Hughes TP, White DL. OCT1 and imatinib transport in CML: is it clinically relevant? Leukemia. PMID 26122430 DOI: 10.1038/Leu.2015.170  1
2015 Hughes TP, Saglio G, Quintás-Cardama A, Mauro MJ, Kim DW, Lipton JH, Bradley-Garelik MB, Ukropec J, Hochhaus A. BCR-ABL1 mutation development during first-line treatment with dasatinib or imatinib for chronic myeloid leukemia in chronic phase. Leukemia. PMID 26118315 DOI: 10.1038/Leu.2015.168  1
2015 Scheffer M, Barrett S, Carpenter SR, Folke C, Green AJ, Holmgren M, Hughes TP, Kosten S, van de Leemput IA, Nepstad DC, van Nes EH, Peeters ET, Walker B. Climate and conservation. Creating a safe operating space for iconic ecosystems. Science (New York, N.Y.). 347: 1317-9. PMID 25792318 DOI: 10.1126/Science.Aaa3769  1
2015 Lu L, Saunders VA, Leclercq TM, Hughes TP, White DL. Ponatinib is not transported by ABCB1, ABCG2 or OCT-1 in CML cells. Leukemia. PMID 25676419 DOI: 10.1038/leu.2015.35  1
2015 Bartley PA, Latham S, Budgen B, Ross DM, Hughes E, Branford S, White D, Hughes TP, Morley AA. A DNA real-time quantitative PCR method suitable for routine monitoring of low levels of minimal residual disease in chronic myeloid leukemia. The Journal of Molecular Diagnostics : Jmd. 17: 185-92. PMID 25554588 DOI: 10.1016/j.jmoldx.2014.10.002  1
2015 Yeung DT, Osborn MP, White DL, Branford S, Braley J, Herschtal A, Kornhauser M, Issa S, Hiwase DK, Hertzberg M, Schwarer AP, Filshie R, Arthur CK, Kwan YL, Trotman J, ... ... Hughes TP, et al. TIDEL-II: first-line use of imatinib in CML with early switch to nilotinib for failure to achieve time-dependent molecular targets. Blood. 125: 915-23. PMID 25519749 DOI: 10.1182/blood-2014-07-590315  1
2015 Yeung DT, Moulton DJ, Heatley SL, Nievergall E, Dang P, Braley J, Branford S, Moore S, Mullighan CG, Hughes TP, White DL. Relapse of BCR-ABL1-like ALL mediated by the ABL1 kinase domain mutation T315I following initial response to dasatinib treatment. Leukemia. 29: 230-2. PMID 25179732 DOI: 10.1038/leu.2014.256  1
2015 Lickliter JD, Taylor K, Szer J, Grigg A, Arthur C, Hughes TP, Durrant S, Filshie R, Irving I, Seldon M, Ellacott J, Boyd AW, D'Rozario J, Rooney K, Lynch K, et al. An imatinib-only window followed by imatinib and chemotherapy for Philadelphia chromosome-positive acute leukemia: long-term results of the CMLALL1 trial. Leukemia & Lymphoma. 56: 630-8. PMID 24844361 DOI: 10.3109/10428194.2014.925547  1
2015 Schafranek L, Nievergall E, Powell JA, Hiwase DK, Leclercq T, Hughes TP, White DL. Sustained inhibition of STAT5, but not JAK2, is essential for TKI-induced cell death in chronic myeloid leukemia. Leukemia. 29: 76-85. PMID 24813920 DOI: 10.1038/leu.2014.156  1
2015 White DL, Hughes TP. Living with CML: Is death no longer the end (point)? Blood. 126: 2-4. DOI: 10.1182/blood-2015-05-644732  1
2015 Hughes TP, Day JC, Brodie J. Securing the future of the Great Barrier Reef Nature Climate Change. 5: 508-511. DOI: 10.1038/Nclimate2604  1
2015 Fischer J, Gardner TA, Bennett EM, Balvanera P, Biggs R, Carpenter S, Daw T, Folke C, Hill R, Hughes TP, Luthe T, Maass M, Meacham M, Norström AV, Peterson G, et al. Advancing sustainability through mainstreaming a social-ecological systems perspective Current Opinion in Environmental Sustainability. 14: 144-149. DOI: 10.1016/J.Cosust.2015.06.002  1
2015 Ong J, Yeung D, Filshie R, Hughes TP, Nandurkar H. Imatinib-induced gastric antral vascular ectasia in three patients with chronic myeloid leukaemia International Journal of Hematology. DOI: 10.1007/s12185-015-1824-y  1
2015 Ross DM, Hughes TP. Discontinuation of therapy and treatment-free remission in CML Molecular Pathogenesis and Treatment of Chronic Myelogenous Leukemia. 183-193. DOI: 10.1007/978-4-431-55714-2_12  1
2014 Hughes TP, Bellwood DR, Connolly SR, Cornell HV, Karlson RH. Double jeopardy and global extinction risk in corals and reef fishes. Current Biology : Cb. 24: 2946-51. PMID 25454782 DOI: 10.1016/J.Cub.2014.10.037  1
2014 Roberts KG, Li Y, Payne-Turner D, Harvey RC, Yang YL, Pei D, McCastlain K, Ding L, Lu C, Song G, Ma J, Becksfort J, Rusch M, Chen SC, Easton J, ... ... Hughes TP, et al. Targetable kinase-activating lesions in Ph-like acute lymphoblastic leukemia. The New England Journal of Medicine. 371: 1005-15. PMID 25207766 DOI: 10.1056/Nejmoa1403088  1
2014 Parker WT, Phillis SR, Yeung DT, Hughes TP, Scott HS, Branford S. Many BCR-ABL1 compound mutations reported in chronic myeloid leukemia patients may actually be artifacts due to PCR-mediated recombination. Blood. 124: 153-5. PMID 24993880 DOI: 10.1182/blood-2014-05-573485  1
2014 Hughes TP, Lipton JH, Spector N, Cervantes F, Pasquini R, Clementino NC, Dorlhiac Llacer PE, Schwarer AP, Mahon FX, Rea D, Branford S, Purkayastha D, Collins L, Szczudlo T, Leber B. Deep molecular responses achieved in patients with CML-CP who are switched to nilotinib after long-term imatinib. Blood. 124: 729-36. PMID 24948656 DOI: 10.1182/blood-2013-12-544015  1
2014 Branford S, Yeung DT, Parker WT, Roberts ND, Purins L, Braley JA, Altamura HK, Yeoman AL, Georgievski J, Jamison BA, Phillis S, Donaldson Z, Leong M, Fletcher L, Seymour JF, ... ... Hughes TP, et al. Prognosis for patients with CML and >10% BCR-ABL1 after 3 months of imatinib depends on the rate of BCR-ABL1 decline. Blood. 124: 511-8. PMID 24859364 DOI: 10.1182/Blood-2014-03-566323  1
2014 Ross DM, Hughes TP. How I determine if and when to recommend stopping tyrosine kinase inhibitor treatment for chronic myeloid leukaemia. British Journal of Haematology. 166: 3-11. PMID 24754670 DOI: 10.1111/bjh.12892  1
2014 Baccarani M, Druker BJ, Branford S, Kim DW, Pane F, Mongay L, Mone M, Ortmann CE, Kantarjian HM, Radich JP, Hughes TP, Cortes JE, Guilhot F. Long-term response to imatinib is not affected by the initial dose in patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: final update from the Tyrosine Kinase Inhibitor Optimization and Selectivity (TOPS) study. International Journal of Hematology. 99: 616-24. PMID 24658916 DOI: 10.1007/S12185-014-1566-2  1
2014 Hughes TP, Hochhaus A, Kantarjian HM, Cervantes F, Guilhot F, Niederwieser D, le Coutre PD, Rosti G, Ossenkoppele G, Lobo C, Shibayama H, Fan X, Menssen HD, Kemp C, Larson RA, et al. Safety and efficacy of switching to nilotinib 400 mg twice daily for patients with chronic myeloid leukemia in chronic phase with suboptimal response or failure on front-line imatinib or nilotinib 300 mg twice daily. Haematologica. 99: 1204-11. PMID 24532039 DOI: 10.3324/haematol.2013.091272  1
2014 Nievergall E, Ramshaw HS, Yong AS, Biondo M, Busfield SJ, Vairo G, Lopez AF, Hughes TP, White DL, Hiwase DK. Monoclonal antibody targeting of IL-3 receptor α with CSL362 effectively depletes CML progenitor and stem cells. Blood. 123: 1218-28. PMID 24363400 DOI: 10.1182/blood-2012-12-475194  1
2014 Hughes TP, Saglio G, Kantarjian HM, Guilhot F, Niederwieser D, Rosti G, Nakaseko C, De Souza CA, Kalaycio ME, Meier S, Fan X, Menssen HD, Larson RA, Hochhaus A. Early molecular response predicts outcomes in patients with chronic myeloid leukemia in chronic phase treated with frontline nilotinib or imatinib. Blood. 123: 1353-60. PMID 24335106 DOI: 10.1182/blood-2013-06-510396  1
2014 Kok CH, Leclercq T, Watkins DB, Saunders V, Wang J, Hughes TP, White DL. Elevated PTPN2 expression is associated with inferior molecular response in de-novo chronic myeloid leukaemia patients. Leukemia. 28: 702-5. PMID 24192813 DOI: 10.1038/leu.2013.329  1
2014 Eadie LN, Hughes TP, White DL. Interaction of the efflux transporters ABCB1 and ABCG2 with imatinib, nilotinib, and dasatinib. Clinical Pharmacology and Therapeutics. 95: 294-306. PMID 24107928 DOI: 10.1038/clpt.2013.208  1
2014 Jabbour EJ, Hughes TP, Cortés JE, Kantarjian HM, Hochhaus A. Potential mechanisms of disease progression and management of advanced-phase chronic myeloid leukemia. Leukemia & Lymphoma. 55: 1451-62. PMID 24050507 DOI: 10.3109/10428194.2013.845883  1
2014 Barrett S, Lenton TM, Millner A, Tavoni A, Carpenter S, Anderies JM, Chapin FS, Crépin AS, Daily G, Ehrlich P, Folke C, Galaz V, Hughes T, Kautsky N, Lambin EF, et al. Climate engineering reconsidered Nature Climate Change. 4: 527-529. DOI: 10.1038/Nclimate2278  1
2013 Baccarani M, Deininger MW, Rosti G, Hochhaus A, Soverini S, Apperley JF, Cervantes F, Clark RE, Cortes JE, Guilhot F, Hjorth-Hansen H, Hughes TP, Kantarjian HM, Kim DW, Larson RA, et al. European LeukemiaNet recommendations for the management of chronic myeloid leukemia: 2013. Blood. 122: 872-84. PMID 23803709 DOI: 10.1182/blood-2013-05-501569  1
2013 Parker WT, Yeoman AL, Jamison BA, Yeung DT, Scott HS, Hughes TP, Branford S. BCR-ABL1 kinase domain mutations may persist at very low levels for many years and lead to subsequent TKI resistance. British Journal of Cancer. 109: 1593-8. PMID 23799845 DOI: 10.1038/bjc.2013.318  1
2013 Hughes TP, Carpenter S, Rockström J, Scheffer M, Walker B. Multiscale regime shifts and planetary boundaries. Trends in Ecology & Evolution. 28: 389-95. PMID 23769417 DOI: 10.1016/J.Tree.2013.05.019  1
2013 Ross DM, Branford S, Seymour JF, Schwarer AP, Arthur C, Yeung DT, Dang P, Goyne JM, Slader C, Filshie RJ, Mills AK, Melo JV, White DL, Grigg AP, Hughes TP. Safety and efficacy of imatinib cessation for CML patients with stable undetectable minimal residual disease: results from the TWISTER study. Blood. 122: 515-22. PMID 23704092 DOI: 10.1182/blood-2013-02-483750  1
2013 Keith SA, Baird AH, Hughes TP, Madin JS, Connolly SR. Faunal breaks and species composition of Indo-Pacific corals: the role of plate tectonics, environment and habitat distribution. Proceedings. Biological Sciences / the Royal Society. 280: 20130818. PMID 23698011 DOI: 10.1098/Rspb.2013.0818  1
2013 Ross DM, O'Hely M, Bartley PA, Dang P, Score J, Goyne JM, Sobrinho-Simoes M, Cross NC, Melo JV, Speed TP, Hughes TP, Morley AA. Distribution of genomic breakpoints in chronic myeloid leukemia: analysis of 308 patients. Leukemia. 27: 2105-7. PMID 23588714 DOI: 10.1038/Leu.2013.116  1
2013 Stein AM, Martinelli G, Hughes TP, Müller MC, Beppu L, Gottardi E, Branford S, Soverini S, Woodman RC, Hochhaus A, Kim DW, Saglio G, Radich JP. Rapid initial decline in BCR-ABL1 is associated with superior responses to second-line nilotinib in patients with chronic-phase chronic myeloid leukemia. Bmc Cancer. 13: 173. PMID 23547655 DOI: 10.1186/1471-2407-13-173  1
2013 Thomas D, Powell JA, Green BD, Barry EF, Ma Y, Woodcock J, Fitter S, Zannettino AC, Pitson SM, Hughes TP, Lopez AF, Shepherd PR, Wei AH, Ekert PG, Guthridge MA. Protein kinase activity of phosphoinositide 3-kinase regulates cytokine-dependent cell survival. Plos Biology. 11: e1001515. PMID 23526884 DOI: 10.1371/Journal.Pbio.1001515  1
2013 Branford S, Yeung DT, Ross DM, Prime JA, Field CR, Altamura HK, Yeoman AL, Georgievski J, Jamison BA, Phillis S, Sullivan B, Briggs NE, Hertzberg M, Seymour JF, Reynolds J, ... Hughes TP, et al. Early molecular response and female sex strongly predict stable undetectable BCR-ABL1, the criteria for imatinib discontinuation in patients with CML. Blood. 121: 3818-24. PMID 23515925 DOI: 10.1182/blood-2012-10-462291  1
2013 Hochhaus A, Saglio G, Larson RA, Kim DW, Etienne G, Rosti G, De Souza C, Kurokawa M, Kalaycio ME, Hoenekopp A, Fan X, Shou Y, Kantarjian HM, Hughes TP. Nilotinib is associated with a reduced incidence of BCR-ABL mutations vs imatinib in patients with newly diagnosed chronic myeloid leukemia in chronic phase. Blood. 121: 3703-8. PMID 23502220 DOI: 10.1182/blood-2012-04-423418  1
2013 Kok CH, Watkins DB, Leclercq T, D'Andrea RJ, Hughes TP, White DL. Low GFI1 expression in white blood cells of CP-CML patients at diagnosis is strongly associated with subsequent blastic transformation. Leukemia. 27: 1427-30. PMID 23411466 DOI: 10.1038/leu.2013.47  1
2013 Jabbour E, le Coutre PD, Cortes J, Giles F, Bhalla KN, Pinilla-Ibarz J, Larson RA, Gattermann N, Ottmann OG, Hochhaus A, Hughes TP, Saglio G, Radich JP, Kim DW, Martinelli G, et al. Prediction of outcomes in patients with Ph+ chronic myeloid leukemia in chronic phase treated with nilotinib after imatinib resistance/intolerance. Leukemia. 27: 907-13. PMID 23174881 DOI: 10.1038/Leu.2012.305  1
2013 White DL, Eadie LN, Saunders VA, Hiwase DK, Hughes TP. Proton pump inhibitors significantly increase the intracellular concentration of nilotinib, but not imatinib in target CML cells. Leukemia. 27: 1201-4. PMID 23164803 DOI: 10.1038/leu.2012.295  1
2013 Vandyke K, Fitter S, Drew J, Fukumoto S, Schultz CG, Sims NA, Yeung DT, Hughes TP, Zannettino AC. Prospective histomorphometric and DXA evaluation of bone remodeling in imatinib-treated CML patients: evidence for site-specific skeletal effects. The Journal of Clinical Endocrinology and Metabolism. 98: 67-76. PMID 23144472 DOI: 10.1210/jc.2012-2426  1
2013 Hughes TP, Huang H, Young MA. The wicked problem of China's disappearing coral reefs. Conservation Biology : the Journal of the Society For Conservation Biology. 27: 261-9. PMID 23140101 DOI: 10.1111/J.1523-1739.2012.01957.X  1
2013 Hiwase DK, Saunders VA, Nievergall E, Ross DD, White DL, Hughes TP. Dasatinib targets chronic myeloid leukemia-CD34+ progenitors as effectively as it targets mature cells. Haematologica. 98: 896-900. PMID 23065516 DOI: 10.3324/haematol.2012.070268  1
2013 Hughes TP, Linares C, Dakos V, van de Leemput IA, van Nes EH. Living dangerously on borrowed time during slow, unrecognized regime shifts. Trends in Ecology & Evolution. 28: 149-55. PMID 22995893 DOI: 10.1016/J.Tree.2012.08.022  1
2013 Angelini S, Soverini S, Ravegnini G, Barnett M, Turrini E, Thornquist M, Pane F, Hughes TP, White DL, Radich J, Kim DW, Saglio G, Cilloni D, Iacobucci I, Perini G, et al. Association between imatinib transporters and metabolizing enzymes genotype and response in newly diagnosed chronic myeloid leukemia patients receiving imatinib therapy. Haematologica. 98: 193-200. PMID 22875622 DOI: 10.3324/haematol.2012.066480  1
2013 Eadie LN, Saunders VA, Hughes TP, White DL. Degree of kinase inhibition achieved in vitro by imatinib and nilotinib is decreased by high levels of ABCB1 but not ABCG2. Leukemia & Lymphoma. 54: 569-78. PMID 22845311 DOI: 10.3109/10428194.2012.715345  1
2013 Watkins DB, Hughes TP, White DL, D'Andrea RJ. NPM1 mutations occur rarely or not at all in chronic myeloid leukaemia patients in chronic phase or blast crisis. Leukemia. 27: 489-90. PMID 22791379 DOI: 10.1038/leu.2012.193  1
2013 Giles FJ, le Coutre PD, Pinilla-Ibarz J, Larson RA, Gattermann N, Ottmann OG, Hochhaus A, Radich JP, Saglio G, Hughes TP, Martinelli G, Kim DW, Novick S, Gillis K, Fan X, et al. Nilotinib in imatinib-resistant or imatinib-intolerant patients with chronic myeloid leukemia in chronic phase: 48-month follow-up results of a phase II study. Leukemia. 27: 107-12. PMID 22763385 DOI: 10.1038/Leu.2012.181  1
2013 Schafranek L, Leclercq TM, White DL, Hughes TP. Clarithromycin enhances dasatinib-induced cell death in chronic myeloid leukemia cells, by inhibition of late stage autophagy. Leukemia & Lymphoma. 54: 198-201. PMID 22656271 DOI: 10.3109/10428194.2012.698737  1
2013 Graham NAJ, Bellwood DR, Cinner JE, Hughes TP, Norström AV, Nyström M. Managing resilience to reverse phase shifts in coral reefs Frontiers in Ecology and the Environment. 11: 541-548. DOI: 10.1890/120305  1
2013 Palmer JA, Boerner JJ, Hughes TP, Bennett GR. Engineered plasma interactions for geomagnetic propulsion of ultra small satellites Proceedings of Spie - the International Society For Optical Engineering. 8739. DOI: 10.1117/12.2010789  1
2013 Madrid EA, Welch DR, Clark RE, Rose DV, Mostrom CB, Stygar WA, Cuneo ME, Gomez MR, Hughes TP, Pointon TD, Seidel DB. Numerical simulations of a post-hole convolute driven by high power magnetically insulated transmission lines: Analysis of current loss in steady-state and time-dependent operating modes Digest of Technical Papers-Ieee International Pulsed Power Conference. DOI: 10.1109/PPC.2013.6627602  1
2013 Schulze ME, Ekdahl CA, Hughes TP, Thoma C. Ion production and rf generation in the DARHT-II beam dump Digest of Technical Papers-Ieee International Pulsed Power Conference. DOI: 10.1109/PPC.2013.6627455  1
2013 Madrid EA, Rose DV, Welch DR, Clark RE, Mostrom CB, Stygar WA, Cuneo ME, Gomez MR, Hughes TP, Pointon TD, Seidel DB. Steady-state modeling of current loss in a post-hole convolute driven by high power magnetically insulated transmission lines Physical Review Special Topics - Accelerators and Beams. 16. DOI: 10.1103/Physrevstab.16.120401  1
2013 Bridge TCL, Hughes TP, Guinotte JM, Bongaerts P. Call to protect all coral reefs Nature Climate Change. 3: 528-530. DOI: 10.1038/Nclimate1879  1
2013 Levin S, Xepapadeas T, Crépin AS, Norberg J, De Zeeuw A, Folke C, Hughes T, Arrow K, Barrett S, Daily G, Ehrlich P, Kautsky N, Mäler KG, Polasky S, Troell M, et al. Social-ecological systems as complex adaptive systems: Modeling and policy implications Environment and Development Economics. 18: 111-132. DOI: 10.1017/S1355770X12000460  1
2013 Rockström J, Steffen W, Noone K, Persson A, Chapin FS, Lambin EF, Lenton TM, Scheffer M, Folke C, Joachim H, Schnellhuber, Nykvist B, de Wit CA, Hughes T, van der Leeuw S, et al. A safe operating space for humanity The Future of Nature: Documents of Global Change. 491-501.  1
2012 Branford S, Kim DW, Soverini S, Haque A, Shou Y, Woodman RC, Kantarjian HM, Martinelli G, Radich JP, Saglio G, Hochhaus A, Hughes TP, Müller MC. Initial molecular response at 3 months may predict both response and event-free survival at 24 months in imatinib-resistant or -intolerant patients with Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase treated with nilotinib. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 4323-9. PMID 23109697 DOI: 10.1200/JCO.2011.40.5217  1
2012 Madin JS, Hughes TP, Connolly SR. Calcification, storm damage and population resilience of tabular corals under climate change. Plos One. 7: e46637. PMID 23056379 DOI: 10.1371/Journal.Pone.0046637  1
2012 Hughes T. Providing information to children before and during venepuncture Nursing Children and Young People. 24: 23-28. PMID 22774662  1
2012 Larson RA, Hochhaus A, Hughes TP, Clark RE, Etienne G, Kim DW, Flinn IW, Kurokawa M, Moiraghi B, Yu R, Blakesley RE, Gallagher NJ, Saglio G, Kantarjian HM. Nilotinib vs imatinib in patients with newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia in chronic phase: ENESTnd 3-year follow-up. Leukemia. 26: 2197-203. PMID 22699418 DOI: 10.1038/leu.2012.134  1
2012 Yin OQ, Giles FJ, Baccarani M, le Coutre P, Chiparus O, Gallagher N, Saglio G, Hughes TP, Hochhaus A, Kantarjian HM, Larson RA. Concurrent use of proton pump inhibitors or H2 blockers did not adversely affect nilotinib efficacy in patients with chronic myeloid leukemia. Cancer Chemotherapy and Pharmacology. 70: 345-50. PMID 22623211 DOI: 10.1007/s00280-012-1881-3  1
2012 Wang J, Hughes TP, Kok CH, Saunders VA, Frede A, Groot-Obbink K, Osborn M, Somogyi AA, D'Andrea RJ, White DL. Contrasting effects of diclofenac and ibuprofen on active imatinib uptake into leukaemic cells. British Journal of Cancer. 106: 1772-8. PMID 22531634 DOI: 10.1038/bjc.2012.173  1
2012 Blake SJ, Hughes TP, Lyons AB. Drug-interaction studies evaluating T-cell proliferation reveal distinct activity of dasatinib and imatinib in combination with cyclosporine A. Experimental Hematology. 40: 612-21.e6. PMID 22521768 DOI: 10.1016/j.exphem.2012.04.003  1
2012 Hughes TP, Baird AH, Dinsdale EA, Moltschaniwskyj NA, Pratchett MS, Tanner JE, Willis BL. Assembly rules of reef corals are flexible along a steep climatic gradient. Current Biology : Cb. 22: 736-41. PMID 22503500 DOI: 10.1016/J.Cub.2012.02.068  1
2012 Hiwase DK, Hughes TP. Sudden blast crisis in chronic myeloid leukemia treated with tyrosine kinase inhibitors. Leukemia & Lymphoma. 53: 1251-2. PMID 22475357 DOI: 10.3109/10428194.2012.682314  1
2012 Yeung DT, Hughes TP. Therapeutic targeting of BCR-ABL: prognostic markers of response and resistance mechanism in chronic myeloid leukaemia. Critical Reviews in Oncogenesis. 17: 17-30. PMID 22471662  1
2012 Hanfstein B, Müller MC, Hehlmann R, Erben P, Lauseker M, Fabarius A, Schnittger S, Haferlach C, Göhring G, Proetel U, Kolb HJ, Krause SW, Hofmann WK, Schubert J, Einsele H, ... ... Hughes TP, et al. Early molecular and cytogenetic response is predictive for long-term progression-free and overall survival in chronic myeloid leukemia (CML). Leukemia. 26: 2096-102. PMID 22446502 DOI: 10.1038/leu.2012.85  1
2012 Branford S, Yeung DT, Prime JA, Choi SY, Bang JH, Park JE, Kim DW, Ross DM, Hughes TP. BCR-ABL1 doubling times more reliably assess the dynamics of CML relapse compared with the BCR-ABL1 fold rise: implications for monitoring and management. Blood. 119: 4264-71. PMID 22431575 DOI: 10.1182/blood-2011-11-393041  1
2012 Nieborowska-Skorska M, Kopinski PK, Ray R, Hoser G, Ngaba D, Flis S, Cramer K, Reddy MM, Koptyra M, Penserga T, Glodkowska-Mrowka E, Bolton E, Holyoake TL, Eaves CJ, Cerny-Reiterer S, ... ... Hughes TP, et al. Rac2-MRC-cIII-generated ROS cause genomic instability in chronic myeloid leukemia stem cells and primitive progenitors. Blood. 119: 4253-63. PMID 22411871 DOI: 10.1182/Blood-2011-10-385658  1
2012 White DL, Hughes TP. Classification of patients with chronic myeloid leukemia on basis of BCR-ABL transcript level at 3 months fails to identify patients with low organic cation transporter-1 activity destined to have poor imatinib response. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 30: 1144-5; author reply. PMID 22393079 DOI: 10.1200/JCO.2011.41.1090  1
2012 Guilhot F, Hughes TP, Cortes J, Druker BJ, Baccarani M, Gathmann I, Hayes M, Granvil C, Wang Y. Plasma exposure of imatinib and its correlation with clinical response in the Tyrosine Kinase Inhibitor Optimization and Selectivity Trial. Haematologica. 97: 731-8. PMID 22315495 DOI: 10.3324/Haematol.2011.045666  1
2012 Parker WT, Ho M, Scott HS, Hughes TP, Branford S. Poor response to second-line kinase inhibitors in chronic myeloid leukemia patients with multiple low-level mutations, irrespective of their resistance profile. Blood. 119: 2234-8. PMID 22210874 DOI: 10.1182/blood-2011-08-375535  1
2012 White DL, Radich J, Soverini S, Saunders VA, Frede AK, Dang P, Cilloni D, Lin P, Mongay L, Woodman R, Manley P, Slader C, Kim DW, Pane F, Martinelli G, ... ... Hughes TP, et al. Chronic phase chronic myeloid leukemia patients with low OCT-1 activity randomized to high-dose imatinib achieve better responses and have lower failure rates than those randomized to standard-dose imatinib. Haematologica. 97: 907-14. PMID 22207690 DOI: 10.3324/haematol.2011.056457  1
2012 Larson RA, Yin OQ, Hochhaus A, Saglio G, Clark RE, Nakamae H, Gallagher NJ, Demirhan E, Hughes TP, Kantarjian HM, le Coutre PD. Population pharmacokinetic and exposure-response analysis of nilotinib in patients with newly diagnosed Ph+ chronic myeloid leukemia in chronic phase. European Journal of Clinical Pharmacology. 68: 723-33. PMID 22207416 DOI: 10.1007/s00228-011-1200-7  1
2012 Bellwood DR, Hoey AS, Hughes TP. Human activity selectively impacts the ecosystem roles of parrotfishes on coral reefs. Proceedings. Biological Sciences / the Royal Society. 279: 1621-9. PMID 22090383 DOI: 10.1098/Rspb.2011.1906  1
2012 Jabbour E, Saglio G, Hughes TP, Kantarjian H. Suboptimal responses in chronic myeloid leukemia: implications and management strategies. Cancer. 118: 1181-91. PMID 22038681 DOI: 10.1002/cncr.26391  1
2012 Carpenter SR, Arrow KJ, Barrett S, Biggs R, Brock WA, Crépin AS, Engström G, Folke C, Hughes TP, Kautsky N, Li CZ, Mccarney G, Meng K, Mäler KG, Polasky S, et al. General resilience to cope with extreme events Sustainability. 4: 3248-3259. DOI: 10.3390/Su4123248  1
2012 Carpenter SR, Folke C, Norström A, Olsson O, Schultz L, Agarwal B, Balvanera P, Campbell B, Castilla JC, Cramer W, DeFries R, Eyzaguirre P, Hughes TP, Polasky S, Sanusi Z, et al. Program on ecosystem change and society: An international research strategy for integrated social-ecological systems Current Opinion in Environmental Sustainability. 4: 134-138. DOI: 10.1016/J.Cosust.2012.01.001  1
2012 Bijker W, Pinch T, Hughes TP. The social construction of technological systems: New directions in the sociology and history of technology: Anniversary edition The Social Construction of Technological Systems: New Directions in the Sociology and History of Technology: Anniversary Edition. 1-425.  1
2012 Hughes TP. The evolution of large technological systems The Social Construction of Technological Systems: New Directions in the Sociology and History of Technology: Anniversary Edition. 45-76.  1
2012 Yeung DT, Hughes TP. Therapeutic targeting of BCR-ABL: Prognostic markers of response and resistance mechanism in chronicmyeloid leukaemia Critical Reviews in Oncogenesis. 17: 17-30.  1
2011 Parker WT, Lawrence RM, Ho M, Irwin DL, Scott HS, Hughes TP, Branford S. Sensitive detection of BCR-ABL1 mutations in patients with chronic myeloid leukemia after imatinib resistance is predictive of outcome during subsequent therapy. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 29: 4250-9. PMID 21990409 DOI: 10.1200/JCO.2011.35.0934  1
2011 Stein AM, Bottino D, Modur V, Branford S, Kaeda J, Goldman JM, Hughes TP, Radich JP, Hochhaus A. BCR-ABL transcript dynamics support the hypothesis that leukemic stem cells are reduced during imatinib treatment. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 6812-21. PMID 21903771 DOI: 10.1158/1078-0432.Ccr-11-0396  1
2011 Kantarjian HM, Hochhaus A, Saglio G, De Souza C, Flinn IW, Stenke L, Goh YT, Rosti G, Nakamae H, Gallagher NJ, Hoenekopp A, Blakesley RE, Larson RA, Hughes TP. Nilotinib versus imatinib for the treatment of patients with newly diagnosed chronic phase, Philadelphia chromosome-positive, chronic myeloid leukaemia: 24-month minimum follow-up of the phase 3 randomised ENESTnd trial. The Lancet. Oncology. 12: 841-51. PMID 21856226 DOI: 10.1016/S1470-2045(11)70201-7  1
2011 Esposito N, Colavita I, Quintarelli C, Sica AR, Peluso AL, Luciano L, Picardi M, Del Vecchio L, Buonomo T, Hughes TP, White D, Radich JP, Russo D, Branford S, Saglio G, et al. SHP-1 expression accounts for resistance to imatinib treatment in Philadelphia chromosome-positive cells derived from patients with chronic myeloid leukemia. Blood. 118: 3634-44. PMID 21821701 DOI: 10.1182/blood-2011-03-341073  1
2011 Steneck RS, Hughes TP, Cinner JE, Adger WN, Arnold SN, Berkes F, Boudreau SA, Brown K, Folke C, Gunderson L, Olsson P, Scheffer M, Stephenson E, Walker B, Wilson J, et al. Creation of a gilded trap by the high economic value of the Maine lobster fishery. Conservation Biology : the Journal of the Society For Conservation Biology. 25: 904-12. PMID 21797925 DOI: 10.1111/J.1523-1739.2011.01717.X  1
2011 Karlson RH, Connolly SR, Hughes TP. Spatial variance in abundance and occupancy of corals across broad geographic scales. Ecology. 92: 1282-91. PMID 21797156 DOI: 10.1890/10-0619.1  1
2011 Tang C, Schafranek L, Watkins DB, Parker WT, Moore S, Prime JA, White DL, Hughes TP. Tyrosine kinase inhibitor resistance in chronic myeloid leukemia cell lines: investigating resistance pathways. Leukemia & Lymphoma. 52: 2139-47. PMID 21718141 DOI: 10.3109/10428194.2011.591013  1
2011 Tang M, Gonen M, Quintas-Cardama A, Cortes J, Kantarjian H, Field C, Hughes TP, Branford S, Michor F. Dynamics of chronic myeloid leukemia response to long-term targeted therapy reveal treatment effects on leukemic stem cells. Blood. 118: 1622-31. PMID 21653938 DOI: 10.1182/Blood-2011-02-339267  1
2011 White DL, Hughes TP. Predicting the response of CML patients to tyrosine kinase inhibitor therapy. Current Hematologic Malignancy Reports. 6: 88-95. PMID 21448598 DOI: 10.1007/s11899-011-0087-9  1
2011 Engler JR, Hughes TP, White DL. OCT-1 as a determinant of response to antileukemic treatment. Clinical Pharmacology and Therapeutics. 89: 608-11. PMID 21346750 DOI: 10.1038/Clpt.2011.12  1
2011 Branford S, Hughes TP. Mutational analysis in chronic myeloid leukemia: when and what to do? Current Opinion in Hematology. 18: 111-6. PMID 21245758 DOI: 10.1097/MOH.0b013e32834399ef  1
2011 Kantarjian HM, Giles FJ, Bhalla KN, Pinilla-Ibarz J, Larson RA, Gattermann N, Ottmann OG, Hochhaus A, Radich JP, Saglio G, Hughes TP, Martinelli G, Kim DW, Shou Y, Gallagher NJ, et al. Nilotinib is effective in patients with chronic myeloid leukemia in chronic phase after imatinib resistance or intolerance: 24-month follow-up results. Blood. 117: 1141-5. PMID 21098399 DOI: 10.1182/Blood-2010-03-277152  1
2011 Engler JR, Zannettino AC, Bailey CG, Rasko JE, Hughes TP, White DL. OCT-1 function varies with cell lineage but is not influenced by BCR-ABL. Haematologica. 96: 213-20. PMID 20971815 DOI: 10.3324/haematol.2010.033290  1
2011 Ross DM, Hughes TP, Melo JV. Do we have to kill the last CML cell? Leukemia. 25: 193-200. PMID 20844563 DOI: 10.1038/leu.2010.197  1
2011 Kerr AM, Baird AH, Hughes TP. Correlated evolution of sex and reproductive mode in corals (Anthozoa: Scleractinia). Proceedings. Biological Sciences / the Royal Society. 278: 75-81. PMID 20659935 DOI: 10.1098/Rspb.2010.1196  1
2011 Hughes TP, Bellwood DR, Baird AH, Brodie J, Bruno JF, Pandolfi JM. Shifting base-lines, declining coral cover, and the erosion of reef resilience: Comment on Sweatman et al. (2011) Coral Reefs. 30: 653-660. DOI: 10.1007/S00338-011-0787-6  1
2011 Hiwase DK, Hughes TP. Therapy of Advanced-Stage and Resistant Chronic Myeloid Leukemia Leukemias: Principles and Practice of Therapy. 281-295. DOI: 10.1002/9781444327359.ch23  1
2011 Ekdahl C, Abeyta EO, Johnson JB, Nielsen K, Schulze ME, Tom CY, Hughes TP, Thoma CH. Minimizing beam motion in a long-pulse linear induction accelerator Ipac 2011 - 2nd International Particle Accelerator Conference. 2109-2111.  1
2011 Alexander W, Hughes TP. American Society of Hematology, 52nd Annual Meeting and Exposition: Nilotinib (Tasigna) found superior to imatinib (Gleevec) in chronic-phase chronic myeloid leukemia: ENESTnd update P and T. 36: 100-101.  1
2010 Branford S, Hughes TP. Practical considerations for monitoring patients with chronic myeloid leukemia. Seminars in Hematology. 47: 327-34. PMID 20875549 DOI: 10.1053/j.seminhematol.2010.06.007  1
2010 Gelcich S, Hughes TP, Olsson P, Folke C, Defeo O, Fernández M, Foale S, Gunderson LH, Rodríguez-Sickert C, Scheffer M, Steneck RS, Castilla JC. Navigating transformations in governance of Chilean marine coastal resources. Proceedings of the National Academy of Sciences of the United States of America. 107: 16794-9. PMID 20837530 DOI: 10.1073/Pnas.1012021107  1
2010 White DL, Saunders VA, Dang P, Engler J, Hughes TP. OCT-1 activity measurement provides a superior imatinib response predictor than screening for single-nucleotide polymorphisms of OCT-1. Leukemia. 24: 1962-5. PMID 20811406 DOI: 10.1038/leu.2010.188  1
2010 Ross DM, Branford S, Seymour JF, Schwarer AP, Arthur C, Bartley PA, Slader C, Field C, Dang P, Filshie RJ, Mills AK, Grigg AP, Melo JV, Hughes TP. Patients with chronic myeloid leukemia who maintain a complete molecular response after stopping imatinib treatment have evidence of persistent leukemia by DNA PCR. Leukemia. 24: 1719-24. PMID 20811403 DOI: 10.1038/leu.2010.185  1
2010 Hughes TP, Graham NA, Jackson JB, Mumby PJ, Steneck RS. Rising to the challenge of sustaining coral reef resilience. Trends in Ecology & Evolution. 25: 633-42. PMID 20800316 DOI: 10.1016/J.Tree.2010.07.011  1
2010 Hughes TP, Hochhaus A, Branford S, Müller MC, Kaeda JS, Foroni L, Druker BJ, Guilhot F, Larson RA, O'Brien SG, Rudoltz MS, Mone M, Wehrle E, Modur V, Goldman JM, et al. Long-term prognostic significance of early molecular response to imatinib in newly diagnosed chronic myeloid leukemia: an analysis from the International Randomized Study of Interferon and STI571 (IRIS). Blood. 116: 3758-65. PMID 20679528 DOI: 10.1182/Blood-2010-03-273979  1
2010 Fraser CK, Lousberg EL, Guerin LR, Hughes TP, Brown MP, Diener KR, Hayball JD. Dasatinib alters the metastatic phenotype of B16-OVA melanoma in vivo. Cancer Biology & Therapy. 10: 715-27. PMID 20676039 DOI: 10.4161/cbt.10.7.12926  1
2010 Engler JR, Frede A, Saunders V, Zannettino A, White DL, Hughes TP. The poor response to imatinib observed in CML patients with low OCT-1 activity is not attributable to lower uptake of imatinib into their CD34+ cells. Blood. 116: 2776-8. PMID 20634379 DOI: 10.1182/blood-2010-01-267013  1
2010 Saglio G, Kim DW, Issaragrisil S, le Coutre P, Etienne G, Lobo C, Pasquini R, Clark RE, Hochhaus A, Hughes TP, Gallagher N, Hoenekopp A, Dong M, Haque A, Larson RA, et al. Nilotinib versus imatinib for newly diagnosed chronic myeloid leukemia. The New England Journal of Medicine. 362: 2251-9. PMID 20525993 DOI: 10.1056/NEJMoa0912614  1
2010 Bartley PA, Ross DM, Latham S, Martin-Harris MH, Budgen B, Wilczek V, Branford S, Hughes TP, Morley AA. Sensitive detection and quantification of minimal residual disease in chronic myeloid leukaemia using nested quantitative PCR for BCR-ABL DNA. International Journal of Laboratory Hematology. 32: e222-8. PMID 20491997 DOI: 10.1111/J.1751-553X.2010.01236.X  1
2010 Fitter S, Vandyke K, Schultz CG, White D, Hughes TP, Zannettino AC. Plasma adiponectin levels are markedly elevated in imatinib-treated chronic myeloid leukemia (CML) patients: a mechanism for improved insulin sensitivity in type 2 diabetic CML patients? The Journal of Clinical Endocrinology and Metabolism. 95: 3763-7. PMID 20466781 DOI: 10.1210/jc.2010-0086  1
2010 White DL, Dang P, Engler J, Frede A, Zrim S, Osborn M, Saunders VA, Manley PW, Hughes TP. Functional activity of the OCT-1 protein is predictive of long-term outcome in patients with chronic-phase chronic myeloid leukemia treated with imatinib. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 2761-7. PMID 20421539 DOI: 10.1200/JCO.2009.26.5819  1
2010 McCook LJ, Ayling T, Cappo M, Choat JH, Evans RD, De Freitas DM, Heupel M, Hughes TP, Jones GP, Mapstone B, Marsh H, Mills M, Molloy FJ, Pitcher CR, Pressey RL, et al. Adaptive management of the Great Barrier Reef: a globally significant demonstration of the benefits of networks of marine reserves. Proceedings of the National Academy of Sciences of the United States of America. 107: 18278-85. PMID 20176947 DOI: 10.1073/Pnas.0909335107  1
2010 Eadie L, Hughes TP, White DL. Nilotinib does not significantly reduce imatinib OCT-1 activity in either cell lines or primary CML cells. Leukemia. 24: 855-7. PMID 20147980 DOI: 10.1038/leu.2010.7  1
2010 Engler JR, Frede A, Saunders VA, Zannettino AC, Hughes TP, White DL. Chronic myeloid leukemia CD34+ cells have reduced uptake of imatinib due to low OCT-1 activity. Leukemia. 24: 765-70. PMID 20147974 DOI: 10.1038/leu.2010.16  1
2010 Hiwase DK, White DL, Powell JA, Saunders VA, Zrim SA, Frede AK, Guthridge MA, Lopez AF, D'Andrea RJ, To LB, Melo JV, Kumar S, Hughes TP. Blocking cytokine signaling along with intense Bcr-Abl kinase inhibition induces apoptosis in primary CML progenitors. Leukemia. 24: 771-8. PMID 20130598 DOI: 10.1038/leu.2009.299  1
2010 Hiwase DK, White D, Zrim S, Saunders V, Melo JV, Hughes TP. Nilotinib-mediated inhibition of ABCB1 increases intracellular concentration of dasatinib in CML cells: implications for combination TKI therapy. Leukemia. 24: 658-60. PMID 20010623 DOI: 10.1038/leu.2009.242  1
2010 Cortes JE, Baccarani M, Guilhot F, Druker BJ, Branford S, Kim DW, Pane F, Pasquini R, Goldberg SL, Kalaycio M, Moiraghi B, Rowe JM, Tothova E, De Souza C, Rudoltz M, ... ... Hughes TP, et al. Phase III, randomized, open-label study of daily imatinib mesylate 400 mg versus 800 mg in patients with newly diagnosed, previously untreated chronic myeloid leukemia in chronic phase using molecular end points: tyrosine kinase inhibitor optimization and selectivity study. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 424-30. PMID 20008622 DOI: 10.1200/Jco.2009.25.3724  1
2010 Vandyke K, Fitter S, Dewar AL, Hughes TP, Zannettino AC. Dysregulation of bone remodeling by imatinib mesylate. Blood. 115: 766-74. PMID 19890095 DOI: 10.1182/blood-2009-08-237404  1
2010 Hughes TP, Marmier A, Evans KE. Auxetic frameworks inspired by cubic crystals International Journal of Solids and Structures. 47: 1469-1476. DOI: 10.1016/j.ijsolstr.2010.02.002  1
2009 White DL, Hughes TP. Predicting the response of CML patients to tyrosine kinase inhibitor therapy. Current Hematologic Malignancy Reports. 4: 59-65. PMID 20425416 DOI: 10.1007/s11899-009-0009-2  1
2009 Hughes TP, Branford S. Monitoring disease response to tyrosine kinase inhibitor therapy in CML. Hematology / the Education Program of the American Society of Hematology. American Society of Hematology. Education Program. 477-87. PMID 20008233 DOI: 10.1182/asheducation-2009.1.477  1
2009 Connolly SR, Dornelas M, Bellwood DR, Hughes TP. Testing species abundance models: a new bootstrap approach applied to Indo-Pacific coral reefs. Ecology. 90: 3138-49. PMID 19967869 DOI: 10.1890/08-1832.1  1
2009 Branford S, Melo JV, Hughes TP. Selecting optimal second-line tyrosine kinase inhibitor therapy for chronic myeloid leukemia patients after imatinib failure: does the BCR-ABL mutation status really matter? Blood. 114: 5426-35. PMID 19880502 DOI: 10.1182/blood-2009-08-215939  1
2009 Fraser CK, Lousberg EL, Kumar R, Hughes TP, Diener KR, Hayball JD. Dasatinib inhibits the secretion of TNF-alpha following TLR stimulation in vitro and in vivo. Experimental Hematology. 37: 1435-44. PMID 19786067 DOI: 10.1016/j.exphem.2009.09.007  1
2009 Rockström J, Steffen W, Noone K, Persson A, Chapin FS, Lambin EF, Lenton TM, Scheffer M, Folke C, Schellnhuber HJ, Nykvist B, de Wit CA, Hughes T, van der Leeuw S, Rodhe H, et al. A safe operating space for humanity. Nature. 461: 472-5. PMID 19779433 DOI: 10.1038/461472A  1
2009 Müller MC, Cortes JE, Kim DW, Druker BJ, Erben P, Pasquini R, Branford S, Hughes TP, Radich JP, Ploughman L, Mukhopadhyay J, Hochhaus A. Dasatinib treatment of chronic-phase chronic myeloid leukemia: analysis of responses according to preexisting BCR-ABL mutations. Blood. 114: 4944-53. PMID 19779040 DOI: 10.1182/Blood-2009-04-214221  1
2009 Hughes TP, Branford S. Measuring minimal residual disease in chronic myeloid leukemia: fluorescence in situ hybridization and polymerase chain reaction. Clinical Lymphoma & Myeloma. 9: S266-71. PMID 19778851 DOI: 10.3816/CLM.2009.s.022  1
2009 Walker B, Barrett S, Polasky S, Galaz V, Folke C, Engström G, Ackerman F, Arrow K, Carpenter S, Chopra K, Daily G, Ehrlich P, Hughes T, Kautsky N, Levin S, et al. Environment. Looming global-scale failures and missing institutions. Science (New York, N.Y.). 325: 1345-6. PMID 19745137 DOI: 10.1126/Science.1175325  1
2009 Hochhaus A, Müller MC, Radich J, Branford S, Kantarjian HM, Hanfstein B, Rousselot P, Kim DW, Lipton JH, Bleickardt E, Lambert A, Hughes TP. Dasatinib-associated major molecular responses in patients with chronic myeloid leukemia in chronic phase following imatinib failure: response dynamics and predictive value. Leukemia. 23: 1628-33. PMID 19641527 DOI: 10.1038/leu.2009.156  1
2009 Vandyke K, Dewar AL, Fitter S, Menicanin D, To LB, Hughes TP, Zannettino ACW. Imatinib mesylate causes growth plate closure in vivo Leukemia. 23: 2155-2159. PMID 19626049 DOI: 10.1038/leu.2009.150  1
2009 Apperley JF, Cortes JE, Kim DW, Roy L, Roboz GJ, Rosti G, Bullorsky EO, Abruzzese E, Hochhaus A, Heim D, de Souza CA, Larson RA, Lipton JH, Khoury HJ, Kim HJ, ... ... Hughes TP, et al. Dasatinib in the treatment of chronic myeloid leukemia in accelerated phase after imatinib failure: the START a trial. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 3472-9. PMID 19487385 DOI: 10.1200/JCO.2007.14.3339  1
2009 Viswanathan SR, Powers JT, Einhorn W, Hoshida Y, Ng TL, Toffanin S, O'Sullivan M, Lu J, Phillips LA, Lockhart VL, Shah SP, Tanwar PS, Mermel CH, Beroukhim R, Azam M, ... ... Hughes TP, et al. Lin28 promotes transformation and is associated with advanced human malignancies. Nature Genetics. 41: 843-8. PMID 19483683 DOI: 10.1038/Ng.392  1
2009 Blake SJ, Lyons AB, Hughes TP. Nilotinib inhibits the Src-family kinase LCK and T-cell function in vitro. Journal of Cellular and Molecular Medicine. 13: 599-601. PMID 19374687 DOI: 10.1111/j.1582-4934.2009.00500_1.x  1
2009 Tanner JE, Hughes TP, Connell JH. Community-level density dependence: an example from a shallow coral assemblage. Ecology. 90: 506-16. PMID 19323234 DOI: 10.1890/08-0399.1  1
2009 Hochhaus A, O'Brien SG, Guilhot F, Druker BJ, Branford S, Foroni L, Goldman JM, Müller MC, Radich JP, Rudoltz M, Mone M, Gathmann I, Hughes TP, Larson RA. Six-year follow-up of patients receiving imatinib for the first-line treatment of chronic myeloid leukemia Leukemia. 23: 1054-1061. PMID 19282833 DOI: 10.1038/Leu.2009.38  1
2009 Hiwase DK, White DL, Saunders VA, Kumar S, Melo JV, Hughes TP. Short-term intense Bcr-Abl kinase inhibition with nilotinib is adequate to trigger cell death in BCR-ABL+ cells Leukemia. 23: 1205-1206. PMID 19262594 DOI: 10.1038/leu.2009.45  1
2009 Ross DM, Schafranek L, Hughes TP, Nicola M, Branford S, Score J. Genomic translocation breakpoint sequences are conserved in BCR-ABL1 cell lines despite the presence of amplification Cancer Genetics and Cytogenetics. 189: 138-139. PMID 19215797 DOI: 10.1016/j.cancergencyto.2008.10.010  1
2009 Cinner JE, McClanahan TR, Daw TM, Graham NA, Maina J, Wilson SK, Hughes TP. Linking social and ecological systems to sustain coral reef fisheries. Current Biology : Cb. 19: 206-12. PMID 19211057 DOI: 10.1016/J.Cub.2008.11.055  1
2009 Guilhot F, Hughes TP, Kim DW, Cortes JE, Khoury HJ. Dasatinib treatment for philadelphia chromosome-positive leukemias Cancer. 115: 1381-1394. PMID 19195046 DOI: 10.1002/cncr.24155  1
2009 Vandyke K, Dewar AL, Farrugia AN, Fitter S, Bik To L, Hughes TP, Zannettino ACW. Therapeutic concentrations of dasatinib inhibit in vitro osteoclastogenesis Leukemia. 23: 994-997. PMID 19092851 DOI: 10.1038/leu.2008.356  1
2009 Fraser CK, Blake SJ, Diener KR, Lyons AB, Brown MP, Hughes TP, Hayball JD. Dasatinib inhibits recombinant viral antigen-specific murine CD4+ and CD8+ T-cell responses and NK-cell cytolytic activity in vitro and in vivo. Experimental Hematology. 37: 256-65. PMID 19056158 DOI: 10.1016/j.exphem.2008.09.013  1
2009 Ross DM, Branford S, Melo JV, Hughes TP. Reply to 'What do we mean by sensitivity when we talk about detecting minimal residual disease?' by Steinbach and Debatin Leukemia. 23: 819-820. PMID 19020541 DOI: 10.1038/Leu.2008.330  1
2009 Rockström J, Steffen W, Noone K, Persson A, Chapin FS, Lambin E, Lenton TM, Scheffer M, Folke C, Schellnhuber HJ, Nykvist B, de Wit CA, Hughes T, van der Leeuw S, Rodhe H, et al. Planetary boundaries: Exploring the safe operating space for humanity Ecology and Society. 14. DOI: 10.5751/Es-03180-140232  1
2009 Hughes TP. SHOT founders' themes and problems Technology and Culture. 50: 594-599. DOI: 10.1353/tech.0.0299  1
2009 Thoma C, Rose DV, Miller CL, Clark RE, Hughes TP. Electromagnetic wave propagation through an overdense magnetized collisional plasma layer Journal of Applied Physics. 106. DOI: 10.1063/1.3195085  1
2009 Thoma C, Welch DR, Hughes TP. Ballistic and snowplow regimes in J×B plasma acceleration Physics of Plasmas. 16. DOI: 10.1063/1.3081550  1
2009 Elmhirst T, Connolly SR, Hughes TP. Connectivity, regime shifts and the resilience of coral reefs Coral Reefs. 28: 949-957. DOI: 10.1007/S00338-009-0530-8  1
2009 Schulze M, Abeyta EO, Archuleta R, Barazza J, Dalmas D, Ekdahl C, Gregory W, Harrison J, Johnson J, Jacquez E, Marroquin P, Mccuistian BT, Mitchell R, Montoya N, Nath S, ... ... Hughes TP, et al. Commissioning the darht-II accelerator downstream transport and target Proceedings of the 24th Linear Accelerator Conference, Linac 2008. 434-436.  1
2009 Hughes TP. Reduction of bcr-abl transcript levels with imatinib (Gleevec) in chronic myeloid leukemia (Chronic Phase) P and T. 34: 96-97.  1
2008 Cross NCP, Daley GQ, Green AR, Hughes TP, Jamieson C, Manley P, Mughal T, Perrotti D, Radich J, Skoda R, Soverini S, Vainchenker W, Verstovsek S, Villeval JL, Goldman JM. BCR-ABL1-positive CML and BCR-ABL1-negative chronic myeloproliferative disorders: Some common and contrasting features Leukemia. 22: 1975-1989. PMID 19002192 DOI: 10.1038/Leu.2008.231  1
2008 Hughes TP, Branford S, White DL, Reynolds J, Koelmeyer R, Seymour JF, Taylor K, Arthur C, Schwarer A, Morton J, Cooney J, Leahy MF, Rowlings P, Catalano J, Hertzberg M, et al. Impact of early dose intensity on cytogenetic and molecular responses in chronic- phase CML patients receiving 600 mg/day of imatinib as initial therapy. Blood. 112: 3965-73. PMID 18768781 DOI: 10.1182/blood-2008-06-161737  1
2008 Ross DM, Watkins DB, Hughes TP, Branford S. Reverse transcription with random pentadecamer primers improves the detection limit of a quantitative PCR assay for BCR-ABL transcripts in chronic myeloid leukemia: Implications for defining sensitivity in minimal residual disease Clinical Chemistry. 54: 1568-1571. PMID 18641042 DOI: 10.1373/clinchem.2008.105916  1
2008 Olsson P, Folke C, Hughes TP. Navigating the transition to ecosystem-based management of the Great Barrier Reef, Australia. Proceedings of the National Academy of Sciences of the United States of America. 105: 9489-94. PMID 18621698 DOI: 10.1073/Pnas.0706905105  1
2008 Ross DM, Hughes TP. How complete is "complete" molecular response in imatinib-treated chronic myeloid leukemia? Leukemia and Lymphoma. 49: 1230-1231. PMID 18604711 DOI: 10.1080/10428190802158461  1
2008 Hiwase DK, Saunders V, Hewett D, Frede A, Zrim S, Dang P, Eadie L, To LB, Melo J, Kumar S, Hughes TP, White DL. Dasatinib cellular uptake and efflux in chronic myeloid leukemia cells: therapeutic implications. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 14: 3881-8. PMID 18559609 DOI: 10.1158/1078-0432.CCR-07-5095  1
2008 Ross DM, Hughes TP. Current and emerging tests for the laboratory monitoring of chronic myeloid leukaemia and related disorders Pathology. 40: 231-246. PMID 18428043 DOI: 10.1080/00313020801916172  1
2008 Mullighan CG, Miller CB, Radtke I, Phillips LA, Dalton J, Ma J, White D, Hughes TP, Le Beau MM, Pui CH, Relling MV, Shurtleff SA, Downing JR. BCR-ABL1 lymphoblastic leukaemia is characterized by the deletion of Ikaros. Nature. 453: 110-4. PMID 18408710 DOI: 10.1038/nature06866  1
2008 Blake SJ, Bruce Lyons A, Fraser CK, Hayball JD, Hughes TP. Dasatinib suppresses in vitro natural killer cell cytotoxicity. Blood. 111: 4415-6. PMID 18398058 DOI: 10.1182/blood-2008-02-138701  1
2008 Blake S, Hughes TP, Mayrhofer G, Lyons AB. The Src/ABL kinase inhibitor dasatinib (BMS-354825) inhibits function of normal human T-lymphocytes in vitro Clinical Immunology. 127: 330-339. PMID 18395492 DOI: 10.1016/j.clim.2008.02.006  1
2008 Andersson CR, Helliwell CA, Bagnall DJ, Hughes TP, Finnegan EJ, Peacock WJ, Dennis ES. The FLX gene of Arabidopsis is required for FRI-dependent activation of FLC expression Plant and Cell Physiology. 49: 191-200. PMID 18156133 DOI: 10.1093/pcp/pcm176  1
2008 Cross NCP, Hughes TP, Hochhaus A, Goldman JM. International standardisation of quantitative real-time RT-PCR for BCR-ABL Leukemia Research. 32: 505-506. PMID 17512589 DOI: 10.1016/j.leukres.2007.03.031  1
2008 Fitter S, Dewar AL, Kostakis P, To LB, Hughes TP, Roberts MM, Lynch K, Vernon-Roberts B, Zannettino ACW. Long-term imatinib therapy promotes bone formation in CML patients Blood. 111: 2538-2547. DOI: 10.1182/blood-2007-07-104281  1
2008 Rose DV, Welch DR, Hughes TP, Clark RE, Stygar WA. Plasma evolution and dynamics in high-power vacuum-transmission-line post-hole convolutes Physical Review Special Topics - Accelerators and Beams. 11. DOI: 10.1103/PhysRevSTAB.11.060401  1
2008 Scheffer M, Van Nes EH, Holmgren M, Hughes T. Pulse-driven loss of top-down control: The critical-rate hypothesis Ecosystems. 11: 226-237. DOI: 10.1007/S10021-007-9118-8  1
2008 Cornell HV, Karlson RH, Hughes TP. Local-regional species richness relationships are linear at very small to large scales in west-central Pacific corals Coral Reefs. 27: 145-151. DOI: 10.1007/S00338-007-0303-1  1
2007 Hughes TP, Gunderson LH, Folke C, Baird AH, Bellwood D, Berkes F, Crona B, Helfgott A, Leslie H, Norberg J, Nyström M, Olsson P, Osterblom H, Scheffer M, Schuttenberg H, et al. Adaptive management of the Great Barrier Reef and the Grand Canyon world heritage areas. Ambio. 36: 586-92. PMID 18074897 DOI: 10.1579/0044-7447(2007)36[586:Amotgb]2.0.Co;2  1
2007 Shah NP, Skaggs BJ, Branford S, Hughes TP, Nicoll JM, Paquette RL, Sawyers CL. Sequential ABL kinase inhibitor therapy selects for compound drug-resistant BCR-ABL mutations with altered oncogenic potency Journal of Clinical Investigation. 117: 2562-2569. PMID 17710227 DOI: 10.1172/Jci30890  1
2007 Cornell HV, Karlson RH, Hughes TP. Scale-dependent variation in coral community similarity across sites, islands, and island groups. Ecology. 88: 1707-15. PMID 17645017 DOI: 10.1890/06-0742.1  1
2007 Karlson RH, Cornell HV, Hughes TP. Aggregation influences coral species richness at multiple spatial scales. Ecology. 88: 170-7. PMID 17489465 DOI: 10.1890/0012-9658(2007)88[170:Aicsra]2.0.Co;2  1
2007 White DL, Saunders VA, Quinn SR, Manley PW, Hughes TP. Imatinib increases the intracellular concentration of nilotinib, which may explain the observed synergy between these drugs. Blood. 109: 3609-10. PMID 17409347 DOI: 10.1182/blood-2006-11-058032  1
2007 Hughes TP, Rodrigues MJ, Bellwood DR, Ceccarelli D, Hoegh-Guldberg O, McCook L, Moltschaniwskyj N, Pratchett MS, Steneck RS, Willis B. Phase shifts, herbivory, and the resilience of coral reefs to climate change. Current Biology : Cb. 17: 360-5. PMID 17291763 DOI: 10.1016/J.Cub.2006.12.049  1
2007 Hochhaus A, Kantarjian HM, Baccarani M, Lipton JH, Apperley JF, Druker BJ, Facon T, Goldberg SL, Cervantes F, Niederwieser D, Silver RT, Stone RM, Hughes TP, Muller MC, Ezzeddine R, et al. Dasatinib induces notable hematologic and cytogenetic responses in chronic-phase chronic myeloid leukemia after failure of imatinib therapy. Blood. 109: 2303-9. PMID 17138817 DOI: 10.1182/Blood-2006-09-047266  1
2007 Hughes TP, Bellwood DR, Folke CS, McCook LJ, Pandolfi JM. No-take areas, herbivory and coral reef resilience. Trends in Ecology & Evolution. 22: 1-3. PMID 17070963 DOI: 10.1016/J.Tree.2006.10.009  1
2007 Thoma C, Hughes TP, Welch D, Rose D, Clark R, Golovkin I, Macfarlane J. Hybrid simulation algorithms for plasma accelerators Ppps-2007 - Pulsed Power Plasma Science 2007. 2: 1449-1452. DOI: 10.1109/PPPS.2007.4652460  1
2007 Tang Y, Hughes TP, Ekdahl CA, Schulze ME. Beam clean-up zone calculations for 2.5mv, 1.4ka experiments on DARHT-2 Ppps-2007 - Pulsed Power Plasma Science 2007. 2: 1257-1260. DOI: 10.1109/PPPS.2007.4652415  1
2007 Hughes TP, Genoni TC, Davis HA, Kang M, Prichard BA. Numerical model of the DARHT-2 accelerating cell Digest of Technical Papers-Ieee International Pulsed Power Conference. 143-146. DOI: 10.1109/PPC.2005.300527  1
2007 Weir JT, Anaya EM, Caporaso GJ, Chambers FW, Chen YJ, Falabella S, Lee BS, Paul AC, Raymond BA, Richardson RA, Watson JA, Chan D, Davis HA, Day LA, Scarpetti RD, ... ... Hughes TP, et al. DARHT II scaled accelerator tests on the ETA II accelerator Digest of Technical Papers-Ieee International Pulsed Power Conference. 136-138. DOI: 10.1109/PPC.2005.300525  1
2007 Dominic Chan KC, Davis HA, Ekdahl CA, Hughes TP, Genoni TC, Tang Y, Schulze ME. Simulations of ion-hose instability with pressure profiles for DARHT-II long-pulse experiments Digest of Technical Papers-Ieee International Pulsed Power Conference. 872-875. DOI: 10.1109/PPC.2005.300431  1
2007 Thoma C, Hughes TP. A beam-slice algorithm for transport of the DARHT-2 accelerator Proceedings of the Ieee Particle Accelerator Conference. 3411-3413. DOI: 10.1109/PAC.2007.4440442  1
2007 Tang Y, Hughes TP, Genoni TC, Ekdahl CA, Schulze ME. Implementation of spread mass model of ion hose instability in Lamda Proceedings of the Ieee Particle Accelerator Conference. 3408-3410. DOI: 10.1109/PAC.2007.4440441  1
2007 Schulze M, Abeyta EO, Aragon P, Archuleta R, Barraza J, Dalmas D, Ekdahl C, Esquibel K, Eversole S, Gallegos R, Harrison J, Johnson J, Jacquez E, Marroquin P, McCuistian BT, ... ... Hughes TP, et al. Commissioning the DARHT-II scaled accelerator downstream transport Proceedings of the Ieee Particle Accelerator Conference. 2627-2629. DOI: 10.1109/PAC.2007.4440372  1
2007 Penin L, Adjeroud M, Pratchett MS, Hughes TP. Spatial distribution of juvenile and adult corals around Moorea (French Polynesia): Implications for population regulation Bulletin of Marine Science. 80: 379-389.  1
2006 Bellwood DR, Hughes TP, Hoey AS. Sleeping functional group drives coral-reef recovery. Current Biology : Cb. 16: 2434-9. PMID 17174918 DOI: 10.1016/J.Cub.2006.10.030  1
2006 Hui CH, Hughes TP. Autologous stem cell collection and autograft for patients with chronic myeloid leukemia in the era of ABL kinase inhibitors: Back to the bench Leukemia and Lymphoma. 47: 1721-1723. PMID 17064975 DOI: 10.1080/10428190600727871  1
2006 White DL, Saunders VA, Dang P, Engler J, Zannettino AC, Cambareri AC, Quinn SR, Manley PW, Hughes TP. OCT-1-mediated influx is a key determinant of the intracellular uptake of imatinib but not nilotinib (AMN107): reduced OCT-1 activity is the cause of low in vitro sensitivity to imatinib. Blood. 108: 697-704. PMID 16597591 DOI: 10.1182/blood-2005-11-4687  1
2006 Berkes F, Hughes TP, Steneck RS, Wilson JA, Bellwood DR, Crona B, Folke C, Gunderson LH, Leslie HM, Norberg J, Nyström M, Olsson P, Osterblom H, Scheffer M, Worm B. Ecology. Globalization, roving bandits, and marine resources. Science (New York, N.Y.). 311: 1557-8. PMID 16543444 DOI: 10.1126/Science.1122804  1
2006 Dornelas M, Connolly SR, Hughes TP. Coral reef diversity refutes the neutral theory of biodiversity. Nature. 440: 80-2. PMID 16511493 DOI: 10.1038/Nature04534  1
2006 Ross DM, Branford S, Moore S, Hughes TP. Limited clinical value of regular bone marrow cytogenetic analysis in imatinib-treated chronic phase CML patients monitored by RQ-PCR for BCR-ABL Leukemia. 20: 664-670. PMID 16482210 DOI: 10.1038/Sj.Leu.2404139  1
2006 Dewar AL, Farrugia AN, Condina MR, To LB, Hughes TP, Vernon-Roberts B, Zannettino ACW. Imatinib as a potential antiresorptive therapy for bone disease Blood. 107: 4334-4337. PMID 16449525 DOI: 10.1182/blood-2005-09-3568  1
2006 Lebel L, Anderies JM, Campbell B, Folke C, Hatfield-Dodds S, Hughes TP, Wilson J. Governance and the capacity to manage resilience in regional social-ecological systems Ecology and Society. 11. DOI: 10.5751/Es-01606-110119  1
2006 Ceccarelli DM, Hughes TP, McCook LJ. Impacts of simulated overfishing on the territoriality of coral reef damselfish Marine Ecology Progress Series. 309: 255-262. DOI: 10.3354/Meps309255  1
2006 Hughes TP. Comments on Lynn Eden's whole world on fire: Organizations, knowledge, & nuclear weapons devastation Social Studies of Science. 36: 641-644. DOI: 10.1177/0306312706064814  1
2006 Thoma C, Hughes TP, Bruner NL, Genoni TC, Welch DR, Clark RE. Monte Carlo versus bulk conductivity modeling of RF breakdown of helium Ieee Transactions On Plasma Science. 34: 910-919. DOI: 10.1109/TPS.2006.873255  1
2006 Dornelas M, Connolly SR, Hughes TP. Erratum: Coral reef diversity refutes the neutral theory of biodiversity Nature. 443: 598-598. DOI: 10.1038/Nature05187  1
2006 Hughes TP. America as second creation Minerva. 44: 219-222. DOI: 10.1007/s11024-006-0010-z  1
2006 Hughes TP, Berkes F, Steneck RS, Wilson JA, Bellwood DR, Crona B, Folke C, Gunderson LH, Leslie HM, Norberg J, Nyström M, Olsson P, Österblom H, Scheffer M, Worm B. Response [3] Science. 313: 614. DOI: 10.1002/pbc.20454  1
2005 Hughes TP, Bellwood DR, Folke C, Steneck RS, Wilson J. New paradigms for supporting the resilience of marine ecosystems. Trends in Ecology & Evolution. 20: 380-6. PMID 16701400 DOI: 10.1016/J.Tree.2005.03.022  1
2005 Connolly SR, Hughes TP, Bellwood DR, Karlson RH. Community structure of corals and reef fishes at multiple scales. Science (New York, N.Y.). 309: 1363-5. PMID 16123298 DOI: 10.1126/Science.1113281  1
2005 Adger WN, Hughes TP, Folke C, Carpenter SR, Rockström J. Social-ecological resilience to coastal disasters. Science (New York, N.Y.). 309: 1036-9. PMID 16099974 DOI: 10.1126/Science.1112122  1
2005 Grigg RW, Dollar SJ, Huppert A, Causey BD, Andrews K, Kruczynski WL, Precht WF, Miller SL, Aronson RB, Bruno JF, Kaufman L, Jackson JBC, Ogden JC, Pandolfi JM, Baron N, ... ... Hughes TP, et al. Reassessing U.S. coral reefs [1] (multiple letters) Science. 308: 1740-1742. PMID 15966074  1
2005 Pandolfi JM, Jackson JB, Baron N, Bradbury RH, Guzman HM, Hughes TP, Kappel CV, Micheli F, Ogden JC, Possingham HP, Sala E. Ecology. Are U.S. coral reefs on the slippery slope to slime? Science (New York, N.Y.). 307: 1725-6. PMID 15774744 DOI: 10.1126/Science.1104258  1
2005 Bellwood DR, Hughes TP, Connolly SR, Tanner J. Environmental and geometric constraints on Indo-Pacific coral reef biodiversity Ecology Letters. 8: 643-651. DOI: 10.1111/J.1461-0248.2005.00763.X  1
2004 Bellwood DR, Hughes TP, Folke C, Nyström M. Confronting the coral reef crisis. Nature. 429: 827-33. PMID 15215854 DOI: 10.1038/Nature02691  1
2004 Karlson RH, Cornell HV, Hughes TP. Coral communities are regionally enriched along an oceanic biodiversity gradient. Nature. 429: 867-70. PMID 15201847 DOI: 10.1038/Nature02685  1
2004 Connell JH, Hughes TP, Wallace CC, Tanner JE, Harms KE, Kerr AM. A long-term study of competition and diversity of corals Ecological Monographs. 74: 179-210. DOI: 10.1890/02-4043  1
2004 Ayre DJ, Hughes TP. Climate change, genotypic diversity and gene flow in reef-building corals Ecology Letters. 7: 273-278. DOI: 10.1111/j.1461-0248.2004.00585.x  1
2003 Aronson RB, Bruno JF, Precht WF, Glynn PW, Harvell CD, Kaufman L, Rogers CS, Shinn EA, Valentine JF. Causes of coral reef degradation. Science (New York, N.Y.). 302: 1502-4; author reply. PMID 14645826 DOI: 10.1126/Science.302.5650.1502B  1
2003 Pandolfi JM, Bradbury RH, Sala E, Hughes TP, Bjorndal KA, Cooke RG, McArdle D, McClenachan L, Newman MJ, Paredes G, Warner RR, Jackson JB. Global trajectories of the long-term decline of coral reef ecosystems. Science (New York, N.Y.). 301: 955-8. PMID 12920296 DOI: 10.1126/Science.1085706  1
2003 Connolly SR, Bellwood DR, Hughes TP. Indo‐Pacific Biodiversity Of Coral Reefs: Deviations From A Mid‐Domain Model Ecology. 84: 2178-2190. DOI: 10.1890/02-0254  1
2003 Hughes T. Biogeographic comparisons of coral faunas Oceanis. 29: 291-301.  1
2003 Connolly SR, Bellwood DR, Hughes TP. Indo-pacific biodiversity of coral reefs: Deviations from a mid-domain model Ecology. 84: 2178-2190.  1
2002 Baird AH, Bellwood DR, Connell JH, Cornell HV, Hughes TP, Karlson RH, Rosen BR. Coral reef biodiversity and conservation. Science (New York, N.Y.). 296: 1026-8; author reply. PMID 12004903 DOI: 10.1126/Science.296.5570.1026  1
2002 Hughes TP, Baird AH, Dinsdale EA, Harriott VJ, Moltschaniwskyj NA, Pratchett MS, Tanner JE, Willis BL. Detecting regional variation using meta-analysis and large-scale sampling: Latitudinal patterns in recruitment Ecology. 83: 436-451. DOI: 10.1890/0012-9658(2002)083[0436:Drvuma]2.0.Co;2  1
2002 Hughes TP, Bellwood DR, Connolly SR. Biodiversity hotspots, centres of endemicity, and the conservation of coral reefs Ecology Letters. 5: 775-784. DOI: 10.1046/J.1461-0248.2002.00383.X  1
2002 Strathmann RR, Hughes TP, Kuris AM, Lindeman KC, Morgan SG, Pandolfi JM, Warner RR. Evolution of local recruitment and its consequences for marine populations Bulletin of Marine Science. 70: 377-396.  1
2001 Veron JEN, Bellwood DR, Hughes TP. The state of coral reef science [5] (multiple letters) Science. 293: 1996-1997. PMID 11558534  1
2001 Jackson JB, Kirby MX, Berger WH, Bjorndal KA, Botsford LW, Bourque BJ, Bradbury RH, Cooke R, Erlandson J, Estes JA, Hughes TP, Kidwell S, Lange CB, Lenihan HS, Pandolfi JM, et al. Historical overfishing and the recent collapse of coastal ecosystems. Science (New York, N.Y.). 293: 629-37. PMID 11474098 DOI: 10.1126/Science.1059199  1
2001 Bellwood DR, Hughes TP. Regional-scale assembly rules and biodiversity of coral reefs. Science (New York, N.Y.). 292: 1532-5. PMID 11375488 DOI: 10.1126/Science.1058635  1
2000 Ayre DJ, Hughes TP. Genotypic diversity and gene flow in brooding and spawning corals along the great barrier reef, Australia Evolution. 54: 1590-1605. PMID 11108587 DOI: 10.1111/J.0014-3820.2000.Tb00704.X  1
2000 Hughes TP, Tanner JE. Recruitment failure, life histories, and long-term decline of Caribbean corals Ecology. 81: 2250-2263. DOI: 10.1890/0012-9658(2000)081[2250:Rflhal]2.0.Co;2  1
2000 Hughes TP, Baird AH, Dinsdale EA, Moltschaniwskyj NA, Pratchett MS, Tanner JE, Willis BL. Supply-side ecology works both ways: The link between benthic adults, fecundity, and larval recruits Ecology. 81: 2241-2249. DOI: 10.1890/0012-9658(2000)081[2241:Ssewbw]2.0.Co;2  1
2000 Baird AH, Hughes TP. Competitive dominance by tabular corals: An experimental analysis of recruitment and survival of understorey assemblages Journal of Experimental Marine Biology and Ecology. 251: 117-132. DOI: 10.1016/S0022-0981(00)00209-4  1
1999 Hughes T, Szmant AM, Steneck R, Carpenter R, Miller S, Lapointe BE. Algal blooms on coral reefs: What are the causes? Limnology and Oceanography. 44: 1583-1592. DOI: 10.4319/Lo.1999.44.6.1583  1
1999 Hughes TP, Connell JH. Multiple stressors on coral reefs: A long-term perspective Limnology and Oceanography. 44: 932-940. DOI: 10.4319/Lo.1999.44.3_Part_2.0932  1
1999 Hughes TP, Baird AH, Dinsdale EA, Moltschaniwskyj NA, Pratchett MS, Tanner JE, Willis BL. Patterns of recruitment and abundance of corals along the Great Barrier Reef Nature. 397: 59-63. DOI: 10.1038/16237  1
1999 Hughes TP. Off-reef transport of coral fragments at Lizard Island, Australia Marine Geology. 157: 1-6. DOI: 10.1016/S0025-3227(98)00187-X  1
1999 Smith LD, Hughes TP. An experimental assessment of survival, re-attachment and fecundity of coral fragments Journal of Experimental Marine Biology and Ecology. 235: 147-164. DOI: 10.1016/S0022-0981(98)00178-6  1
1997 Ayre DJ, Hughes TP, Standish RJ. Genetic differentiation, reproductive mode, and gene flow in the brooding coral Pocillopora damicornis along the Great Barrier Reef, Australia Marine Ecology Progress Series. 159: 175-187. DOI: 10.3354/Meps159175  1
1997 Grigg RW, Hughes T. Coral Reefs: Progress and change as we approach the 21st Century Coral Reefs. 16: 1-1. DOI: 10.1007/S003380050051  0.2
1997 Connell JH, Hughes TP, Wallace CC. A 30-year study of coral abundance, recruitment, and disturbance at several scales in space and time Ecological Monographs. 67: 461-488.  1
1996 Hughes TP. Demographic approaches to community dynamics: A coral reef example Ecology. 77: 2256-2260. DOI: 10.2307/2265718  1
1996 Karlson RH, Hughes TP, Karlson SR. Density-dependent dynamics of soft coral aggregations: The significance of clonal growth and form Ecology. 77: 1592-1599. DOI: 10.2307/2265554  1
1996 Hall VR, Hughes TP. Reproductive strategies of modular organisms: Comparative studies of reef-building corals Ecology. 77: 950-963. DOI: 10.2307/2265514  1
1996 Caley MJ, Carr MH, Hixon MA, Hughes TP, Jones GP, Menge BA. Recruitment and the local dynamics of open marine populations Annual Review of Ecology and Systematics. 27: 477-500. DOI: 10.1146/Annurev.Ecolsys.27.1.477  1
1996 Tanner JE, Hughes TP, Connell JH. The role of history in community dynamics: A modelling approach Ecology. 77: 108-117.  1
1994 Orr SL, Hughes TP, Sawyers CL, Kato RM, Quan SG, Williams SP, Witte ON, Hood L. Isolation of unknown genes from human bone marrow by differential screening and single-pass cDNA sequence determination. Proceedings of the National Academy of Sciences of the United States of America. 91: 11869-73. PMID 7991548 DOI: 10.1073/Pnas.91.25.11869  0.01
1994 Hughes TP. Catastrophes, phase shifts, and large-scale degradation of a Caribbean coral reef Science. 265: 1547-1551. DOI: 10.1126/Science.265.5178.1547  1
1994 Hughes TP. Coral reef degradation: a long-term study of human and natural impacts Proceedings of the Colloquium On Global Aspects of Coral Reefs, Miami, 1993. 208-213.  1
1994 Tanner JE, Hughes TP, Connell JH. Species coexistence, keystone species, and succession: A sensitivity analysis Ecology. 75: 2204-2219.  1
1994 Hughes TP. Response [4] Science. 266: 1932-1933.  1
1993 Hughes T. Preface Coral Reefs. 12: 115. DOI: 10.1007/BF00334468  1
1993 Hughes T. Disturbance: effects on coral reef dynamics Coral Reefs. 12: 117-233.  1
1992 Hughes TP, Ayre D, Connell JH. The evolutionary ecology of corals Trends in Ecology and Evolution. 7: 292-295. DOI: 10.1016/0169-5347(92)90225-Z  1
1990 Hughes TP. Recruitment limitation, mortality, and population regulation in open systems: a case study Ecology. 71: 12-20.  1
1989 Hughes TP. Community structure and diversity of coral reefs: the role of history Ecology. 70: 275-279. DOI: 10.2307/1938434  1
1987 Hughes TP. Skeletal density and growth form of corals Marine Ecology Progress Series. 35: 259-266. DOI: 10.3354/Meps035259  0.01
1987 Hughes TP, Reed DC, Boyle MJ. Herbivory on coral reefs: community structure following mass mortalities of sea urchins Journal of Experimental Marine Biology and Ecology. 113: 39-59. DOI: 10.1016/0022-0981(87)90081-5  1
1987 Hughes TP, Connell JH. Population dynamics based on size or age? A reef- coral analysis American Naturalist. 129: 818-829.  1
1985 Hughes TP, Jackson JBC. Population Dynamics and Life Histories of Foliaceous Corals Ecological Monographs. 55: 141-166. DOI: 10.2307/1942555  0.88
1985 Jackson JBC, Hughes TP. Adaptive strategies of coral-reef invertebrates American Scientist. 73: 265-274.  1
1980 Hughes TP, Jackson JB. Do corals lie about their age? Some demographic consequences of partial mortality, fission, and fusion. Science (New York, N.Y.). 209: 713-5. PMID 17821194 DOI: 10.1126/Science.209.4457.713  1
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