| Year |
Citation |
Score |
| 2021 |
Nichols JC, Schiffer CA, Royer WE. NAD(H) phosphates mediate tetramer assembly of human C-terminal binding protein (CtBP). The Journal of Biological Chemistry. 100351. PMID 33524397 DOI: 10.1016/j.jbc.2021.100351 |
0.336 |
|
| 2020 |
Jecrois AM, Dcona MM, Deng X, Bandyopadhyay D, Grossman SR, Schiffer CA, Royer WE. Cryo-EM Structure of CtBP2 Confirms Tetrameric Architecture. Structure (London, England : 1993). PMID 33264605 DOI: 10.1016/j.str.2020.11.008 |
0.302 |
|
| 2020 |
Lockbaum GJ, Leidner F, Royer WE, Kurt Yilmaz N, Schiffer CA. Optimizing the refinement of merohedrally twinned P6 HIV-1 protease-inhibitor cocrystal structures. Acta Crystallographica. Section D, Structural Biology. 76: 302-310. PMID 32133994 DOI: 10.1107/S2059798320001989 |
0.326 |
|
| 2020 |
Jecrois AM, Bellesis A, Schiffer C, Royer W. Cryo‐EM Structure of CtBP2 Confirms Tetrameric Architecture The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.04531 |
0.392 |
|
| 2020 |
Royer WE, Nichols JC, Schiffer CA. Illuminating the Structural Determinants for Tetrameric Assembly of Oncogenic CtBP to Guide Inhibitor Design Biophysical Journal. 118: 46a. DOI: 10.1016/J.Bpj.2019.11.430 |
0.351 |
|
| 2019 |
Royer WE, Bellesis AG, Jecrois AM, Hilbert BJ, Dcona MM, Grossman SR, Schiffer CA. Tetrameric Assembly of the Oncogenic C-Terminal Binding Proteins Biophysical Journal. 116: 62a. DOI: 10.1016/J.Bpj.2018.11.380 |
0.373 |
|
| 2018 |
Bellesis AG, Jecrois AM, Hayes JA, Schiffer C, Royer WE. Assembly of human C-terminal Binding Protein (CtBP) into tetramers. The Journal of Biological Chemistry. PMID 29700119 DOI: 10.1074/Jbc.Ra118.002514 |
0.494 |
|
| 2017 |
Kouno T, Silvas TV, Hilbert BJ, Shandilya SMD, Bohn MF, Kelch BA, Royer WE, Somasundaran M, Kurt Yilmaz N, Matsuo H, Schiffer CA. Crystal structure of APOBEC3A bound to single-stranded DNA reveals structural basis for cytidine deamination and specificity. Nature Communications. 8: 15024. PMID 28452355 DOI: 10.1038/Ncomms15024 |
0.451 |
|
| 2017 |
Dcona MM, Morris BL, Damle PK, Nawaz Z, Perez FZ, Dennis MJ, Singh SJ, Royer WE, Ellis KC, Grossman SR. Abstract 3204: Tryptophan 318/324, the target of C-terminal binding protein (CtBP) inhibitors, plays a critical role in CtBP enzymatic activity, oligomerization and transcriptional coregulation Cancer Research. 77: 3204-3204. DOI: 10.1158/1538-7445.Am2017-3204 |
0.316 |
|
| 2016 |
Korwar S, Morris BL, Parikh HI, Coover RA, Doughty TW, Love IM, Hilbert BJ, Royer WE, Kellogg GE, Grossman SR, Ellis KC. Design, synthesis, and biological evaluation of substrate-competitive inhibitors of C-terminal Binding Protein (CtBP). Bioorganic & Medicinal Chemistry. PMID 27156192 DOI: 10.1016/J.Bmc.2016.04.037 |
0.333 |
|
| 2015 |
Hilbert BJ, Morris BL, Ellis KC, Paulsen JL, Schiffer CA, Grossman SR, Royer WE. Structure-guided design of a high affinity inhibitor to human CtBP. Acs Chemical Biology. 10: 1118-27. PMID 25636004 DOI: 10.1021/Cb500820B |
0.413 |
|
| 2014 |
Laine JM, Amat M, Morgan BR, Royer WE, Massi F. Insight into the allosteric mechanism of Scapharca dimeric hemoglobin. Biochemistry. 53: 7199-210. PMID 25356908 DOI: 10.1021/Bi500591S |
0.428 |
|
| 2014 |
Hilbert BJ, Grossman SR, Schiffer CA, Royer WE. Crystal structures of human CtBP in complex with substrate MTOB reveal active site features useful for inhibitor design. Febs Letters. 588: 1743-8. PMID 24657618 DOI: 10.1016/J.Febslet.2014.03.026 |
0.426 |
|
| 2013 |
Ren Z, Chan PW, Moffat K, Pai EF, Royer WE, Šrajer V, Yang X. Resolution of structural heterogeneity in dynamic crystallography. Acta Crystallographica. Section D, Biological Crystallography. 69: 946-59. PMID 23695239 DOI: 10.1107/S0907444913003454 |
0.397 |
|
| 2013 |
Ronda L, Bettati S, Henry ER, Kashav T, Sanders JM, Royer WE, Mozzarelli A. Tertiary and quaternary allostery in tetrameric hemoglobin from Scapharca inaequivalvis. Biochemistry. 52: 2108-17. PMID 23458680 DOI: 10.1021/Bi301620X |
0.507 |
|
| 2012 |
Ren Z, Šrajer V, Knapp JE, Royer WE. Cooperative macromolecular device revealed by meta-analysis of static and time-resolved structures Proceedings of the National Academy of Sciences of the United States of America. 109: 107-112. PMID 22171006 DOI: 10.1073/Pnas.1109213108 |
0.47 |
|
| 2011 |
Royer WE, Knapp J, Ren Z, Cho HS, Anfinrud P, Srajer V. Time Resolved Crystallographic Analysis of Cooperative Ligand Binding and Ligand Migration in a Dimeric Hemoglobin Biophysical Journal. 100: 379a. DOI: 10.1016/J.Bpj.2010.12.2257 |
0.517 |
|
| 2011 |
Anfinrud P, Schotte F, Cho HS, Dashdorj N, Royer W, Soman J, Olson J. Using X-rays to Watch Proteins Function with 100 Picosecond Time Resolution Biophysical Journal. 100: 222a-223a. DOI: 10.1016/J.Bpj.2010.12.1428 |
0.403 |
|
| 2010 |
Shandilya SM, Nalam MN, Nalivaika EA, Gross PJ, Valesano JC, Shindo K, Li M, Munson M, Royer WE, Harjes E, Kono T, Matsuo H, Harris RS, Somasundaran M, Schiffer CA. Crystal structure of the APOBEC3G catalytic domain reveals potential oligomerization interfaces. Structure (London, England : 1993). 18: 28-38. PMID 20152150 DOI: 10.1016/J.Str.2009.10.016 |
0.425 |
|
| 2010 |
Chen W, Royer WE. Structural insights into interferon regulatory factor activation. Cellular Signalling. 22: 883-7. PMID 20043992 DOI: 10.1016/J.Cellsig.2009.12.005 |
0.361 |
|
| 2010 |
Choi J, Muniyappan S, Wallis JT, Royer WE, Ihee H. Protein conformational dynamics of homodimeric hemoglobin revealed by combined time-resolved spectroscopic probes. Chemphyschem : a European Journal of Chemical Physics and Physical Chemistry. 11: 109-14. PMID 19924759 DOI: 10.1002/Cphc.200900822 |
0.316 |
|
| 2009 |
Knapp JE, Pahl R, Cohen J, Nichols JC, Schulten K, Gibson QH, Srajer V, Royer WE. Ligand migration and cavities within Scapharca Dimeric HbI: studies by time-resolved crystallo-graphy, Xe binding, and computational analysis. Structure (London, England : 1993). 17: 1494-504. PMID 19913484 DOI: 10.1016/J.Str.2009.09.004 |
0.428 |
|
| 2009 |
Royer WE, Chen W, Lam SS, Srinath H, Jiang Z, Correia JJ, Schiffer CA, Fitzgerald KA, Lin K. Activation Of Interferon Regulatory Factors Revealed By The Crystal Structure Of Dimeric IRF-5 Biophysical Journal. 96: 586a-587a. DOI: 10.1016/J.Bpj.2008.12.3070 |
0.461 |
|
| 2008 |
Chen W, Lam SS, Srinath H, Jiang Z, Correia JJ, Schiffer CA, Fitzgerald KA, Lin K, Royer WE. Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5. Nature Structural & Molecular Biology. 15: 1213-20. PMID 18836453 DOI: 10.1038/Nsmb.1496 |
0.426 |
|
| 2008 |
Chen W, Srinath H, Lam SS, Schiffer CA, Royer WE, Lin K. Contribution of Ser386 and Ser396 to activation of interferon regulatory factor 3. Journal of Molecular Biology. 379: 251-60. PMID 18440553 DOI: 10.1016/J.Jmb.2008.03.050 |
0.337 |
|
| 2008 |
Šrajer V, Royer WE. Time-Resolved X-Ray Crystallography of Heme Proteins Methods in Enzymology. 437: 379-395. PMID 18433638 DOI: 10.1016/S0076-6879(07)37019-5 |
0.367 |
|
| 2007 |
Nienhaus K, Knapp JE, Palladino P, Royer WE, Nienhaus GU. Ligand migration and binding in the dimeric hemoglobin of Scapharca inaequivalvis. Biochemistry. 46: 14018-31. PMID 18001141 DOI: 10.1021/Bi7016798 |
0.363 |
|
| 2007 |
Chen W, Lam SS, Srinath H, Schiffer CA, Royer WE, Lin K. Competition between Ski and CREB-binding protein for binding to Smad proteins in transforming growth factor-beta signaling. The Journal of Biological Chemistry. 282: 11365-76. PMID 17283070 DOI: 10.1074/Jbc.M700186200 |
0.302 |
|
| 2007 |
Royer WE, Omartian MN, Knapp JE. Low Resolution Crystal Structure of Arenicola Erythrocruorin: Influence of Coiled Coils on the Architecture of a Megadalton Respiratory Protein Journal of Molecular Biology. 365: 226-236. PMID 17084861 DOI: 10.1016/J.Jmb.2006.10.016 |
0.408 |
|
| 2006 |
Nichols JC, Royer WE, Gibson QH. An optical signal correlated with the allosteric transition in Scapharca inaequivalvis HbI. Biochemistry. 45: 15748-55. PMID 17176097 DOI: 10.1021/Bi061451K |
0.313 |
|
| 2006 |
Royer WE, Sharma H, Strand K, Knapp JE, Bhyravbhatla B. Lumbricus erythrocruorin at 3.5 A resolution: architecture of a megadalton respiratory complex. Structure (London, England : 1993). 14: 1167-77. PMID 16843898 DOI: 10.1016/J.Str.2006.05.011 |
0.498 |
|
| 2006 |
Knapp JE, Pahl R, Šrajer V, Royer WE. Allosteric action in real time: Time-resolved crystallographic studies of a cooperative dimeric hemoglobin Proceedings of the National Academy of Sciences of the United States of America. 103: 7649-7654. PMID 16684887 DOI: 10.1073/Pnas.0509411103 |
0.484 |
|
| 2005 |
Knapp JE, Bonham MA, Gibson QH, Nichols JC, Royer WE. Residue F4 plays a key role in modulating oxygen affinity and cooperativity in Scapharca dimeric hemoglobin. Biochemistry. 44: 14419-30. PMID 16262242 DOI: 10.1021/Bi051052+ |
0.421 |
|
| 2005 |
Royer WE, Zhu H, Gorr TA, Flores JF, Knapp JE. Allosteric hemoglobin assembly: diversity and similarity. The Journal of Biological Chemistry. 280: 27477-80. PMID 15932877 DOI: 10.1074/Jbc.R500006200 |
0.347 |
|
| 2005 |
Flores JF, Fisher CR, Carney SL, Green BN, Freytag JK, Schaeffer SW, Royer WE. Sulfide binding is mediated by zinc ions discovered in the crystal structure of a hydrothermal vent tubeworm hemoglobin. Proceedings of the National Academy of Sciences of the United States of America. 102: 2713-8. PMID 15710902 DOI: 10.1073/Pnas.0407455102 |
0.406 |
|
| 2005 |
Srajer V, Pahl R, Knapp J, Royer W, Schmidt M. Studies of heme proteins by time-resolved crystallography: allosteric action and structural relaxation Acta Crystallographica Section a Foundations of Crystallography. 61: c255-c255. DOI: 10.1107/S0108767305089105 |
0.393 |
|
| 2004 |
Strand K, Knapp JE, Bhyravbhatla B, Royer WE. Crystal structure of the hemoglobin dodecamer from Lumbricus erythrocruorin: Allosteric core of giant annelid respiratory complexes Journal of Molecular Biology. 344: 119-134. PMID 15504406 DOI: 10.1016/J.Jmb.2004.08.094 |
0.555 |
|
| 2004 |
Knapp JE, Šrajer V, Pahl R, Royer WE. Immobilization of Scapharca HbI crystals improves data quality in time-resolved crystallographic experiments Micron. 35: 107-108. PMID 15036308 DOI: 10.1016/J.Micron.2003.10.039 |
0.341 |
|
| 2003 |
Bennett EJ, Bjerregaard J, Knapp JE, Chavous DA, Friedman AM, Royer WE, O'Connor CM. Catalytic implications from the Drosophila protein L-isoaspartyl methyltransferase structure and site-directed mutagenesis. Biochemistry. 42: 12844-53. PMID 14596598 DOI: 10.1021/Bi034891+ |
0.451 |
|
| 2003 |
Knapp JE, Royer WE. Ligand-linked structural transitions in crystals of a cooperative dimeric hemoglobin Biochemistry. 42: 4640-4647. PMID 12705827 DOI: 10.1021/Bi027136P |
0.516 |
|
| 2001 |
Knapp JE, Gibson QH, Cushing L, Royer WE. Restricting the ligand-linked heme movement in Scapharca dimeric hemoglobin reveals tight coupling between distal and proximal contributions to cooperativity. Biochemistry. 40: 14795-805. PMID 11732898 DOI: 10.1021/Bi011071T |
0.382 |
|
| 2001 |
Royer WE, Knapp JE, Strand K, Heaslet HA. Cooperative hemoglobins: Conserved fold, diverse quaternary assemblies and allosteric mechanisms Trends in Biochemical Sciences. 26: 297-304. PMID 11343922 DOI: 10.1016/S0968-0004(01)01811-4 |
0.442 |
|
| 2001 |
Heaslet HA, Royer WE. Crystalline ligand transitions in lamprey hemoglobin: Structural evidence for the regulation of oxygen affinity Journal of Biological Chemistry. 276: 26230-26236. PMID 11340069 DOI: 10.1074/Jbc.M101391200 |
0.49 |
|
| 2000 |
Royer WE, Strand K, van Heel M, Hendrickson WA. Structural hierarchy in erythrocruorin, the giant respiratory assemblage of annelids. Proceedings of the National Academy of Sciences of the United States of America. 97: 7107-11. PMID 10860978 DOI: 10.1073/Pnas.97.13.7107 |
0.699 |
|
| 2000 |
Richardson RC, King NM, Harrington DJ, Sun H, Royer WE, Nelson DJ. X-Ray crystal structure and molecular dynamics simulations of silver hake parvalbumin (Isoform B). Protein Science : a Publication of the Protein Society. 9: 73-82. PMID 10739249 DOI: 10.1110/Ps.9.1.73 |
0.454 |
|
| 1999 |
Heaslet HA, Royer WE. The 2.7 A crystal structure of deoxygenated hemoglobin from the sea lamprey (Petromyzon marinus): structural basis for a lowered oxygen affinity and Bohr effect Structure (London, England : 1993). 7: 517-526. PMID 10378271 DOI: 10.1016/S0969-2126(99)80068-9 |
0.53 |
|
| 1998 |
Harringtont DJ, Adachi K, Royer WE. Crystal structure of deoxy-human hemoglobin β6 Glu → Trp: Implications for the structure and formation of the sickle cell fiber Journal of Biological Chemistry. 273: 32690-32696. PMID 9830011 DOI: 10.1074/Jbc.273.49.32690 |
0.421 |
|
| 1998 |
Pardanani A, Gambacurta A, Ascoli F, Royer WE. Mutational destabilization of the critical interface water cluster in Scapharca dimeric hemoglobin: Structural basis for altered allosteric activity Journal of Molecular Biology. 284: 729-739. PMID 9826511 DOI: 10.1006/Jmbi.1998.2195 |
0.418 |
|
| 1997 |
Harrington DJ, Adachi K, Royer WE. The high resolution crystal structure of deoxyhemoglobin S Journal of Molecular Biology. 272: 398-407. PMID 9325099 DOI: 10.1006/Jmbi.1997.1253 |
0.485 |
|
| 1997 |
Pardanani A, Gibson QH, Colotti G, Royer WE. Mutation of residue Phe97 to Leu disrupts the central allosteric pathway in Scapharca dimeric hemoglobin. The Journal of Biological Chemistry. 272: 13171-9. PMID 9148933 DOI: 10.1074/Jbc.272.20.13171 |
0.486 |
|
| 1997 |
Royer WE, Fox RA, Smith FR, Zhu D, Braswell EH. Ligand linked assembly of Scapharca dimeric hemoglobin. The Journal of Biological Chemistry. 272: 5689-94. PMID 9038179 DOI: 10.1074/Jbc.272.9.5689 |
0.408 |
|
| 1996 |
Royer WE, Pardanani A, Gibson QH, Peterson ES, Friedman JM. Ordered water molecules as key allosteric mediators in a cooperative dimeric hemoglobin. Proceedings of the National Academy of Sciences of the United States of America. 93: 14526-31. PMID 8962085 DOI: 10.1073/Pnas.93.25.14526 |
0.432 |
|
| 1995 |
Summerford CM, Pardanani A, Betts AH, Poteete AR, Colotti G, Royer WE. Bacterial expression of Scapharca dimeric hemoglobin: A simple model system for investigating protein cooperativity Protein Engineering, Design and Selection. 8: 593-599. PMID 8532684 DOI: 10.1093/Protein/8.6.593 |
0.439 |
|
| 1995 |
Royer WE, Heard KS, Harrington DJ, Chiancone E. The 2.0 Å crystal structure of Scapharca tetrameric hemoglobin: Cooperative dimers within an allosteric tetramer Journal of Molecular Biology. 253: 168-186. PMID 7473710 DOI: 10.1006/Jmbi.1995.0543 |
0.546 |
|
| 1994 |
Royer WE. High-resolution crystallographic analysis of a co-operative dimeric hemoglobin Journal of Molecular Biology. 235: 657-681. PMID 8289287 DOI: 10.1006/Jmbi.1994.1019 |
0.536 |
|
| 1994 |
Condon PJ, Royer WE. Crystal structure of oxygenated Scapharca dimeric hemoglobin at 1.7-Å resolution Journal of Biological Chemistry. 269: 25259-25267. PMID 7929217 DOI: 10.2210/Pdb1Hbi/Pdb |
0.486 |
|
| 1994 |
Aronson HEG, Royer WE, Hendrickson WA. Quantification of tertiary structural conservation despite primary sequence drift in the globin fold Protein Science. 3: 1706-1711. PMID 7849587 DOI: 10.1002/Pro.5560031009 |
0.645 |
|
| 1991 |
Royer WE, Hendrickson WA, Chiancone E. The 2.4-A crystal structure of Scapharca dimeric hemoglobin. Cooperativity based on directly communicating hemes at a novel subunit interface. Journal of Biological Chemistry. 264: 21052-21061. DOI: 10.2210/Pdb1Sdh/Pdb |
0.681 |
|
| 1990 |
Royer WE, Hendrickson WA, Chiancone E. Structural transitions upon ligand binding in a cooperative dimeric hemoglobin Science. 249: 518-521. PMID 2382132 DOI: 10.1126/Science.2382132 |
0.699 |
|
| 1990 |
Chiancone E, Verzili D, Boffi A, Royer WE, Hendrickson WA. A cooperative hemoglobin with directly communicating hemes The Scapharca inaequivalvis homodimer Biophysical Chemistry. 37: 287-292. PMID 2285790 DOI: 10.1016/0301-4622(90)88028-Q |
0.659 |
|
| 1989 |
Royer WE, Hendrickson WA, Chiancone E. The 2.4-Å crystal structure of Scapharca dimeric hemoglobin. Cooperativity based on directly communicating hemes at a novel subunit interface Journal of Biological Chemistry. 264: 21052-21061. PMID 2592366 |
0.662 |
|
| 1987 |
Royer WE, Hendrickson WA, Love WE. Crystals of Lumbricus erythrocruorin Journal of Molecular Biology. 197: 149-153. PMID 3681992 DOI: 10.1016/0022-2836(87)90618-8 |
0.704 |
|
| 1986 |
Hendrickson WA, Royer WE. Principles in the assembly of annelid erythrocruorins Biophysical Journal. 49: 177-189. PMID 3955169 DOI: 10.1016/S0006-3495(86)83633-5 |
0.663 |
|
| 1985 |
Royer WE, Love WE, Fenderson FF. Cooperative dimeric and tetrameric clam haemoglobins are novel assemblages of myoglobin folds Nature. 316: 277-280. PMID 4022123 DOI: 10.1038/316277A0 |
0.749 |
|
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