Constance L. Cepko - Publications

Affiliations: 
Genetics Harvard Medical School, Boston, MA, United States 
Area:
development of the central nervous system of vertebrates, with an emphasis on the development of the retina; mechanisms of photoreceptor degeneration, and gene therapy for prevention of blindness
Website:
http://genetics.med.harvard.edu/faculty/cepko

239 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Avilés EC, Wang SK, Patel S, Shi S, Lin L, Kefalov VJ, Goodrich LV, Cepko CL, Xue Y. High temporal frequency light response in mouse retina is mediated by ON and OFF bipolar cells and requires FAT3 signaling. Biorxiv : the Preprint Server For Biology. PMID 37961274 DOI: 10.1101/2023.11.02.565326  0.725
2023 Xue Y, Sun X, Wang SK, Collin GB, Kefalov VJ, Cepko CL. Chromophore supply modulates cone function and survival in retinitis pigmentosa mouse models. Proceedings of the National Academy of Sciences of the United States of America. 120: e2217885120. PMID 37252956 DOI: 10.1073/pnas.2217885120  0.697
2022 Wang SK, Cepko CL. Targeting Microglia to Treat Degenerative Eye Diseases. Frontiers in Immunology. 13: 843558. PMID 35251042 DOI: 10.3389/fimmu.2022.843558  0.647
2022 Aytürk DG, You W, Cepko CL. Mouse Lines with Cre-mediated Recombination in Retinal Amacrine Cells. Eneuro. PMID 35045975 DOI: 10.1523/ENEURO.0255-21.2021  0.384
2022 West ER, Lapan SW, Lee C, Kajderowicz KM, Li X, Cepko CL. Spatiotemporal patterns of neuronal subtype genesis suggest hierarchical development of retinal diversity. Cell Reports. 38: 110191. PMID 34986354 DOI: 10.1016/j.celrep.2021.110191  0.788
2021 West ER, Cepko CL. Development and diversification of bipolar interneurons in the mammalian retina. Developmental Biology. PMID 34534525 DOI: 10.1016/j.ydbio.2021.09.005  0.401
2021 Wang SK, Xue Y, Cepko CL. Augmentation of CD47-SIRPα signaling protects cones in genetic models of retinal degeneration. Jci Insight. PMID 34197341 DOI: 10.1172/jci.insight.150796  0.665
2021 Xue Y, Wang SK, Rana P, West ER, Hong CM, Feng H, Wu DM, Cepko CL. AAV-Txnip prolongs cone survival and vision in mouse models of retinitis pigmentosa. Elife. 10. PMID 33847261 DOI: 10.7554/eLife.66240  0.713
2021 Chan YK, Wang SK, Chu CJ, Copland DA, Letizia AJ, Costa Verdera H, Chiang JJ, Sethi M, Wang MK, Neidermyer WJ, Chan Y, Lim ET, Graveline AR, Sanchez M, Boyd RF, ... ... Cepko CL, et al. Engineering adeno-associated viral vectors to evade innate immune and inflammatory responses. Science Translational Medicine. 13. PMID 33568518 DOI: 10.1126/scitranslmed.abd3438  0.651
2021 Wu DM, Ji X, Ivanchenko MV, Chung M, Piper M, Rana P, Wang SK, Xue Y, West E, Zhao SR, Xu H, Cicconet M, Xiong W, Cepko CL. Nrf2 overexpression rescues the RPE in mouse models of retinitis pigmentosa. Jci Insight. 6. PMID 33491671 DOI: 10.1172/jci.insight.145029  0.691
2020 Amamoto R, Garcia MD, West ER, Choi J, Lapan SW, Lane EA, Perrimon N, Cepko CL. Probe-Seq: Method for RNA Sequencing of Specific Cell Types from Animal Tissue. Bio-Protocol. 10: e3749. PMID 33659409 DOI: 10.21769/BioProtoc.3749  0.777
2020 Wang SK, Lapan SW, Hong CM, Krause TB, Cepko CL. Detection of Adeno-associated Viral Vector Genomes with SABER-FISH. Molecular Therapy. Methods & Clinical Development. 19: 376-386. PMID 33209963 DOI: 10.1016/j.omtm.2020.10.003  0.802
2020 Chan CSK, Lonfat N, Zhao R, Davis AE, Li L, Wu MR, Lin CH, Ji Z, Cepko CL, Wang S. Cell type- and stage-specific expression of Otx2 is regulated by multiple transcription factors and -regulatory modules in the retina. Development (Cambridge, England). PMID 32631829 DOI: 10.1242/Dev.187922  0.823
2020 Wang SK, Xue Y, Cepko CL. Microglia modulation by TGF-β1 protects cones in mouse models of retinal degeneration. The Journal of Clinical Investigation. PMID 32352930 DOI: 10.1172/JCI136160  0.681
2020 Luo L, Ambrozkiewicz MC, Benseler F, Chen C, Dumontier E, Falkner S, Furlanis E, Gomez AM, Hoshina N, Huang WH, Hutchison MA, Itoh-Maruoka Y, Lavery LA, Li W, Maruo T, ... ... Cepko CL, et al. Optimizing Nervous System-Specific Gene Targeting with Cre Driver Lines: Prevalence of Germline Recombination and Influencing Factors. Neuron. PMID 32027825 DOI: 10.1016/J.Neuron.2020.01.008  0.313
2020 Perez-Cervantes C, Smith LA, Nadadur RD, Hughes AEO, Wang S, Corbo JC, Cepko C, Lonfat N, Moskowitz IP. Enhancer transcription identifies -regulatory elements for photoreceptor cell types. Development (Cambridge, England). PMID 31915147 DOI: 10.1242/Dev.184432  0.828
2019 Haery L, Deverman BE, Matho KS, Cetin A, Woodard K, Cepko C, Guerin KI, Rego MA, Ersing I, Bachle SM, Kamens J, Fan M. Adeno-Associated Virus Technologies and Methods for Targeted Neuronal Manipulation. Frontiers in Neuroanatomy. 13: 93. PMID 31849618 DOI: 10.3389/fnana.2019.00093  0.363
2019 Amamoto R, Garcia MD, West ER, Choi J, Lapan SW, Lane EA, Perrimon N, Cepko CL. Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by RNA-based isolation. Elife. 8. PMID 31815670 DOI: 10.7554/eLife.51452  0.794
2019 Amamoto R, Zuccaro E, Curry NC, Khurana S, Chen HH, Cepko CL, Arlotta P. FIN-Seq: transcriptional profiling of specific cell types from frozen archived tissue of the human central nervous system. Nucleic Acids Research. PMID 31728515 DOI: 10.1093/nar/gkz968  0.383
2019 Kishi JY, Lapan SW, Beliveau BJ, West ER, Zhu A, Sasaki HM, Saka SK, Wang Y, Cepko CL, Yin P. SABER amplifies FISH: enhanced multiplexed imaging of RNA and DNA in cells and tissues. Nature Methods. PMID 31110282 DOI: 10.1038/S41592-019-0404-0  0.75
2019 Wang SK, Xue Y, Rana P, Hong CM, Cepko CL. Soluble CX3CL1 gene therapy improves cone survival and function in mouse models of retinitis pigmentosa. Proceedings of the National Academy of Sciences of the United States of America. PMID 31036641 DOI: 10.1073/pnas.1901787116  0.739
2019 Xiong W, Wu DM, Xue Y, Wang SK, Chung MJ, Ji X, Rana P, Zhao SR, Mai S, Cepko CL. AAV -regulatory sequences are correlated with ocular toxicity. Proceedings of the National Academy of Sciences of the United States of America. PMID 30833387 DOI: 10.1073/Pnas.1821000116  0.714
2019 Amamoto R, Garcia MD, West ER, Choi J, Lapan SW, Lane EA, Perrimon N, Cepko CL. Author response: Probe-Seq enables transcriptional profiling of specific cell types from heterogeneous tissue by RNA-based isolation Elife. DOI: 10.7554/Elife.51452.Sa2  0.333
2018 Cheong SK, Xiong W, Strazzeri JM, Cepko CL, Williams DR, Merigan WH. In Vivo Functional Imaging of Retinal Neurons Using Red and Green Fluorescent Calcium Indicators. Advances in Experimental Medicine and Biology. 1074: 135-144. PMID 29721937 DOI: 10.1007/978-3-319-75402-4_17  0.352
2018 Guo N, Soden ME, Herber C, Kim MT, Besnard A, Lin P, Ma X, Cepko CL, Zweifel LS, Sahay A. Dentate granule cell recruitment of feedforward inhibition governs engram maintenance and remote memory generalization. Nature Medicine. PMID 29529016 DOI: 10.1038/Nm.4491  0.418
2017 Tang JCY, Rudolph S, Cepko CL. Viral Delivery of GFP-Dependent Recombinases to the Mouse Brain. Methods in Molecular Biology (Clifton, N.J.). 1642: 109-126. PMID 28815497 DOI: 10.1007/978-1-4939-7169-5_8  0.403
2017 da Silva S, Cepko CL. Fgf8 Expression and Degradation of Retinoic Acid Are Required for Patterning a High-Acuity Area in the Retina. Developmental Cell. PMID 28648799 DOI: 10.1016/j.devcel.2017.05.024  0.374
2017 Chinchore Y, Begaj T, Wu D, Drokhlyansky E, Cepko CL. Glycolytic reliance promotes anabolism in photoreceptors. Elife. 6. PMID 28598329 DOI: 10.7554/eLife.25946  0.382
2017 Lonfat N, Cepko C. Epigenomics of Retinal Development in Mice and Humans. Neuron. 94: 420-423. PMID 28472646 DOI: 10.1016/J.Neuron.2017.04.029  0.829
2016 Arendt D, Musser JM, Baker CV, Bergman A, Cepko C, Erwin DH, Pavlicev M, Schlosser G, Widder S, Laubichler MD, Wagner GP. The origin and evolution of cell types. Nature Reviews. Genetics. PMID 27818507 DOI: 10.1038/Nrg.2016.127  0.313
2016 Shekhar K, Lapan SW, Whitney IE, Tran NM, Macosko EZ, Kowalczyk M, Adiconis X, Levin JZ, Nemesh J, Goldman M, McCarroll SA, Cepko CL, Regev A, Sanes JR. Comprehensive Classification of Retinal Bipolar Neurons by Single-Cell Transcriptomics. Cell. 166: 1308-1323.e30. PMID 27565351 DOI: 10.1016/J.Cell.2016.07.054  0.804
2016 Tang JC, Drokhlyansky E, Etemad B, Rudolph S, Guo B, Wang S, Ellis EG, Li JZ, Cepko CL. Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies. Elife. 5. PMID 27205882 DOI: 10.7554/Elife.15312  0.402
2016 Wang S, Cepko CL. Photoreceptor Fate Determination in the Vertebrate Retina. Investigative Ophthalmology & Visual Science. 57: ORSFe1-ORSFe6. PMID 27116662 DOI: 10.1167/iovs.15-17672  0.546
2016 Beier KT, Mundell NA, Pan YA, Cepko CL. Anterograde or Retrograde Transsynaptic Circuit Tracing in Vertebrates with Vesicular Stomatitis Virus Vectors. Current Protocols in Neuroscience / Editorial Board, Jacqueline N. Crawley ... [Et Al.]. 74: 1.26.1-1.26.27. PMID 26729030 DOI: 10.1002/0471142301.Ns0126S74  0.322
2016 Xiong W, Cepko C. Distinct Expression Patterns of AAV8 Vectors with Broadly Active Promoters from Subretinal Injections of Neonatal Mouse Eyes at Two Different Ages. Advances in Experimental Medicine and Biology. 854: 501-7. PMID 26427452 DOI: 10.1007/978-3-319-17121-0_67  0.525
2016 Tang JC, Drokhlyansky E, Etemad B, Rudolph S, Guo B, Wang S, Ellis EG, Li JZ, Cepko CL. Author response: Detection and manipulation of live antigen-expressing cells using conditionally stable nanobodies Elife. DOI: 10.7554/Elife.15312.021  0.359
2015 Cepko CL. The Determination of Rod and Cone Photoreceptor Fate. Annual Review of Vision Science. 1: 211-234. PMID 28532380 DOI: 10.1146/annurev-vision-090814-121657  0.447
2015 Harwell CC, Fuentealba LC, Gonzalez-Cerrillo A, Parker PR, Gertz CC, Mazzola E, Garcia MT, Alvarez-Buylla A, Cepko CL, Kriegstein AR. Wide Dispersion and Diversity of Clonally Related Inhibitory Interneurons. Neuron. PMID 26299474 DOI: 10.1016/j.neuron.2015.07.030  0.566
2015 Mayer C, Jaglin XH, Cobbs LV, Bandler RC, Streicher C, Cepko CL, Hippenmeyer S, Fishell G. Clonally Related Forebrain Interneurons Disperse Broadly across Both Functional Areas and Structural Boundaries. Neuron. 87: 989-98. PMID 26299473 DOI: 10.1016/J.Neuron.2015.07.011  0.36
2015 Tang JC, Rudolph S, Dhande OS, Abraira VE, Choi S, Lapan SW, Drew IR, Drokhlyansky E, Huberman AD, Regehr WG, Cepko CL. Cell type-specific manipulation with GFP-dependent Cre recombinase. Nature Neuroscience. PMID 26258682 DOI: 10.1038/Nn.4081  0.796
2015 Nassi JJ, Cepko CL, Born RT, Beier KT. Neuroanatomy goes viral! Frontiers in Neuroanatomy. 9: 80. PMID 26190977 DOI: 10.3389/fnana.2015.00080  0.337
2015 Cepko C, Punzo C. Cell metabolism: Sugar for sight. Nature. 522: 428-9. PMID 26108850 DOI: 10.1038/522428a  0.334
2015 Fuentealba LC, Rompani SB, Parraguez JI, Obernier K, Romero R, Cepko CL, Alvarez-Buylla A. Embryonic Origin of Postnatal Neural Stem Cells. Cell. 161: 1644-55. PMID 26091041 DOI: 10.1016/j.cell.2015.05.041  0.805
2015 Xiong W, MacColl Garfinkel AE, Li Y, Benowitz LI, Cepko CL. NRF2 promotes neuronal survival in neurodegeneration and acute nerve damage. The Journal of Clinical Investigation. 125: 1433-45. PMID 25798616 DOI: 10.1172/Jci79735  0.373
2015 Mundell NA, Beier KT, Pan YA, Lapan SW, Göz Aytürk D, Berezovskii VK, Wark AR, Drokhlyansky E, Bielecki J, Born RT, Schier AF, Cepko CL. Vesicular stomatitis virus enables gene transfer and transsynaptic tracing in a wide range of organisms. The Journal of Comparative Neurology. 523: 1639-63. PMID 25688551 DOI: 10.1002/Cne.23761  0.765
2014 Wang S, Sengel C, Emerson MM, Cepko CL. A gene regulatory network controls the binary fate decision of rod and bipolar cells in the vertebrate retina. Developmental Cell. 30: 513-27. PMID 25155555 DOI: 10.1016/J.Devcel.2014.07.018  0.453
2014 Cepko C. Intrinsically different retinal progenitor cells produce specific types of progeny Nature Reviews Neuroscience. 15: 615-627. PMID 25096185 DOI: 10.1038/nrn3767  0.439
2014 Sukhdeo K, Koch CE, Miller TE, Zhou H, Rivera M, Yan K, Cepko CL, Lathia JD, Rich JN. The Lgr5 transgene is expressed specifically in glycinergic amacrine cells in the mouse retina. Experimental Eye Research. 119: 106-10. PMID 24246263 DOI: 10.1016/j.exer.2013.11.003  0.54
2014 Cepko C. Cell fate determination of photoreceptor cells Vertebrate Photoreceptors: Functional Molecular Bases. 217-244. DOI: 10.1007/978-4-431-54880-5_9  0.371
2013 Tang JC, Szikra T, Kozorovitskiy Y, Teixiera M, Sabatini BL, Roska B, Cepko CL. A nanobody-based system using fluorescent proteins as scaffolds for cell-specific gene manipulation. Cell. 154: 928-39. PMID 23953120 DOI: 10.1016/J.Cell.2013.07.021  0.821
2013 Jiang H, Wang L, Beier KT, Cepko CL, Fekete DM, Brigande JV. Lineage analysis of the late otocyst stage mouse inner ear by transuterine microinjection of a retroviral vector encoding alkaline phosphatase and an oligonucleotide library. Plos One. 8: e69314. PMID 23935981 DOI: 10.1371/Journal.Pone.0069314  0.487
2013 Emerson MM, Surzenko N, Goetz JJ, Trimarchi J, Cepko CL. Otx2 and Onecut1 promote the fates of cone photoreceptors and horizontal cells and repress rod photoreceptors. Developmental Cell. 26: 59-72. PMID 23867227 DOI: 10.1016/J.Devcel.2013.06.005  0.845
2013 Mizeracka K, DeMaso CR, Cepko CL. Notch1 is required in newly postmitotic cells to inhibit the rod photoreceptor fate. Development (Cambridge, England). 140: 3188-97. PMID 23824579 DOI: 10.1242/Dev.090696  0.849
2013 Mizeracka K, Trimarchi JM, Stadler MB, Cepko CL. Analysis of gene expression in wild-type and Notch1 mutant retinal cells by single cell profiling. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 242: 1147-59. PMID 23813500 DOI: 10.1002/Dvdy.24006  0.861
2013 Whited JL, Tsai SL, Beier KT, White JN, Piekarski N, Hanken J, Cepko CL, Tabin CJ. Pseudotyped retroviruses for infecting axolotl in vivo and in vitro. Development (Cambridge, England). 140: 1137-46. PMID 23344705 DOI: 10.1242/Dev.087734  0.421
2013 Beier KT, Borghuis BG, El-Danaf RN, Huberman AD, Demb JB, Cepko CL. Transsynaptic tracing with vesicular stomatitis virus reveals novel retinal circuitry. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 35-51. PMID 23283320 DOI: 10.1523/JNEUROSCI.0245-12.2013  0.469
2012 Beier K, Cepko C. Viral tracing of genetically defined neural circuitry. Journal of Visualized Experiments : Jove. PMID 23117695 DOI: 10.3791/4253  0.44
2012 Roesch K, Stadler MB, Cepko CL. Gene expression changes within Müller glial cells in retinitis pigmentosa. Molecular Vision. 18: 1197-214. PMID 22665967  0.447
2012 Cepko CL. Emerging gene therapies for retinal degenerations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 6415-20. PMID 22573664 DOI: 10.1523/JNEUROSCI.0295-12.2012  0.487
2012 Hafler BP, Surzenko N, Beier KT, Punzo C, Trimarchi JM, Kong JH, Cepko CL. Transcription factor Olig2 defines subpopulations of retinal progenitor cells biased toward specific cell fates. Proceedings of the National Academy of Sciences of the United States of America. 109: 7882-7. PMID 22543161 DOI: 10.1073/Pnas.1203138109  0.804
2012 Punzo C, Xiong W, Cepko CL. Loss of daylight vision in retinal degeneration: are oxidative stress and metabolic dysregulation to blame? The Journal of Biological Chemistry. 287: 1642-8. PMID 22074929 DOI: 10.1074/Jbc.R111.304428  0.367
2011 Emerson MM, Cepko CL. Identification of a retina-specific Otx2 enhancer element active in immature developing photoreceptors. Developmental Biology. 360: 241-55. PMID 21963459 DOI: 10.1016/J.Ydbio.2011.09.012  0.533
2011 Beier KT, Saunders A, Oldenburg IA, Miyamichi K, Akhtar N, Luo L, Whelan SP, Sabatini B, Cepko CL. Anterograde or retrograde transsynaptic labeling of CNS neurons with vesicular stomatitis virus vectors. Proceedings of the National Academy of Sciences of the United States of America. 108: 15414-9. PMID 21825165 DOI: 10.1073/Pnas.1110854108  0.363
2011 Cronican JJ, Beier KT, Davis TN, Tseng JC, Li W, Thompson DB, Shih AF, May EM, Cepko CL, Kung AL, Zhou Q, Liu DR. A class of human proteins that deliver functional proteins into mammalian cells in vitro and in vivo. Chemistry & Biology. 18: 833-8. PMID 21802004 DOI: 10.1016/J.Chembiol.2011.07.003  0.351
2011 Cherry TJ, Wang S, Bormuth I, Schwab M, Olson J, Cepko CL. NeuroD factors regulate cell fate and neurite stratification in the developing retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 31: 7365-79. PMID 21593321 DOI: 10.1523/Jneurosci.2555-10.2011  0.841
2011 Beier KT, Samson ME, Matsuda T, Cepko CL. Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells. Developmental Biology. 353: 309-20. PMID 21397594 DOI: 10.1016/j.ydbio.2011.03.004  0.487
2011 Huynh MA, Ikeuchi Y, Netherton S, de la Torre-Ubieta L, Kanadia R, Stegmüller J, Cepko C, Bonni S, Bonni A. An isoform-specific SnoN1-FOXO1 repressor complex controls neuronal morphogenesis and positioning in the mammalian brain. Neuron. 69: 930-44. PMID 21382553 DOI: 10.1016/J.Neuron.2011.02.008  0.722
2010 Billings NA, Emerson MM, Cepko CL. Analysis of thyroid response element activity during retinal development. Plos One. 5: e13739. PMID 21060789 DOI: 10.1371/Journal.Pone.0013739  0.82
2010 Cepko C. Seeing the light of day Science. 329: 403-404. PMID 20651144 DOI: 10.1126/science.1194086  0.431
2010 Rompani SB, Cepko CL. A common progenitor for retinal astrocytes and oligodendrocytes. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 4970-80. PMID 20371817 DOI: 10.1523/JNEUROSCI.3456-09.2010  0.815
2010 Bienvenu F, Jirawatnotai S, Elias JE, Meyer CA, Mizeracka K, Marson A, Frampton GM, Cole MF, Odom DT, Odajima J, Geng Y, Zagozdzon A, Jecrois M, Young RA, Liu XS, ... Cepko CL, et al. Transcriptional role of cyclin D1 in development revealed by a genetic-proteomic screen. Nature. 463: 374-8. PMID 20090754 DOI: 10.1038/Nature08684  0.801
2010 Kanadia RN, Cepko CL. Alternative splicing produces high levels of noncoding isoforms of bHLH transcription factors during development. Genes & Development. 24: 229-34. PMID 20080942 DOI: 10.1101/Gad.1847110  0.763
2009 Samson M, Emerson MM, Cepko CL. Robust marking of photoreceptor cells and pinealocytes with several reporters under control of the Crx gene. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 3218-25. PMID 19882727 DOI: 10.1002/Dvdy.22138  0.528
2009 Cherry TJ, Trimarchi JM, Stadler MB, Cepko CL. Development and diversification of retinal amacrine interneurons at single cell resolution. Proceedings of the National Academy of Sciences of the United States of America. 106: 9495-500. PMID 19470466 DOI: 10.1073/pnas.0903264106  0.842
2009 Jadhav AP, Roesch K, Cepko CL. Development and neurogenic potential of Müller glial cells in the vertebrate retina. Progress in Retinal and Eye Research. 28: 249-62. PMID 19465144 DOI: 10.1016/J.Preteyeres.2009.05.002  0.673
2009 Dyer MA, Martins R, da Silva Filho M, Muniz JA, Silveira LC, Cepko CL, Finlay BL. Developmental sources of conservation and variation in the evolution of the primate eye. Proceedings of the National Academy of Sciences of the United States of America. 106: 8963-8. PMID 19451636 DOI: 10.1073/Pnas.0901484106  0.779
2009 Trimarchi JM, Cho SH, Cepko CL. Identification of genes expressed preferentially in the developing peripheral margin of the optic cup. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 238: 2327-9. PMID 19449303 DOI: 10.1002/dvdy.21973  0.755
2009 Chen B, Cepko CL. HDAC4 regulates neuronal survival in normal and diseased retinas. Science (New York, N.Y.). 323: 256-9. PMID 19131628 DOI: 10.1126/Science.1166226  0.437
2009 Punzo C, Kornacker K, Cepko CL. Stimulation of the insulin/mTOR pathway delays cone death in a mouse model of retinitis pigmentosa. Nature Neuroscience. 12: 44-52. PMID 19060896 DOI: 10.1038/nn.2234  0.372
2009 Cepko CL, Golden JA, Szele FG, Lin JC. Lineage analysis in the vertebrate central nervous system Molecular and Cellular Approaches to Neural Development. DOI: 10.1093/acprof:oso/9780195111668.003.0011  0.668
2009 Mizeracka K, Cepko C. 21-P008 Role of Notch signaling in retinal development Mechanisms of Development. 126: S316. DOI: 10.1016/j.mod.2009.06.873  0.794
2008 Kanadia RN, Clark VE, Punzo C, Trimarchi JM, Cepko CL. Temporal requirement of the alternative-splicing factor Sfrs1 for the survival of retinal neurons. Development (Cambridge, England). 135: 3923-33. PMID 18987029 DOI: 10.1242/Dev.024620  0.841
2008 Trimarchi JM, Harpavat S, Billings NA, Cepko CL. Thyroid hormone components are expressed in three sequential waves during development of the chick retina. Bmc Developmental Biology. 8: 101. PMID 18854032 DOI: 10.1186/1471-213X-8-101  0.834
2008 Kim DS, Matsuda T, Cepko CL. A core paired-type and POU homeodomain-containing transcription factor program drives retinal bipolar cell gene expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7748-64. PMID 18667607 DOI: 10.1523/JNEUROSCI.0397-08.2008  0.665
2008 Roesch K, Jadhav AP, Trimarchi JM, Stadler MB, Roska B, Sun BB, Cepko CL. The transcriptome of retinal Müller glial cells. The Journal of Comparative Neurology. 509: 225-38. PMID 18465787 DOI: 10.1002/cne.21730  0.856
2008 Damiani D, Alexander JJ, O'Rourke JR, McManus M, Jadhav AP, Cepko CL, Hauswirth WW, Harfe BD, Strettoi E. Dicer inactivation leads to progressive functional and structural degeneration of the mouse retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 4878-87. PMID 18463241 DOI: 10.1523/Jneurosci.0828-08.2008  0.7
2008 Lagali PS, Balya D, Awatramani GB, Münch TA, Kim DS, Busskamp V, Cepko CL, Roska B. Light-activated channels targeted to ON bipolar cells restore visual function in retinal degeneration. Nature Neuroscience. 11: 667-75. PMID 18432197 DOI: 10.1038/Nn.2117  0.817
2008 Matsuda T, Cepko CL. Analysis of gene function in the retina. Methods in Molecular Biology (Clifton, N.J.). 423: 259-78. PMID 18370205 DOI: 10.1007/978-1-59745-194-9_19  0.431
2008 Punzo C, Cepko CL. Ultrasound-guided in utero injections allow studies of the development and function of the eye. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 1034-42. PMID 18351670 DOI: 10.1002/dvdy.21500  0.413
2008 Trimarchi JM, Stadler MB, Cepko CL. Individual retinal progenitor cells display extensive heterogeneity of gene expression. Plos One. 3: e1588. PMID 18270576 DOI: 10.1371/journal.pone.0001588  0.804
2008 Cepko C, Pear W. Overview of the retrovirus transduction system. Current Protocols in Molecular Biology. Unit9.9. PMID 18265289 DOI: 10.1002/0471142727.Mb0909S36  0.342
2008 Cepko C, Pear W. Retrovirus infection of cells in vitro and in vivo. Current Protocols in Molecular Biology. Unit9.14. PMID 18265282 DOI: 10.1002/0471142727.Mb0914S36  0.44
2008 Kim DS, Ross SE, Trimarchi JM, Aach J, Greenberg ME, Cepko CL. Identification of molecular markers of bipolar cells in the murine retina. The Journal of Comparative Neurology. 507: 1795-810. PMID 18260140 DOI: 10.1002/Cne.21639  0.843
2008 Morrow EM, Chen CM, Cepko CL. Temporal order of bipolar cell genesis in the neural retina. Neural Development. 3: 2. PMID 18215319 DOI: 10.1186/1749-8104-3-2  0.758
2008 Rompani SB, Cepko CL. Retinal progenitor cells can produce restricted subsets of horizontal cells. Proceedings of the National Academy of Sciences of the United States of America. 105: 192-7. PMID 18162542 DOI: 10.1073/pnas.0709979104  0.843
2007 Hsiau TH, Diaconu C, Myers CA, Lee J, Cepko CL, Corbo JC. The cis-regulatory logic of the mammalian photoreceptor transcriptional network. Plos One. 2: e643. PMID 17653270 DOI: 10.1371/journal.pone.0000643  0.806
2007 Corbo JC, Myers CA, Lawrence KA, Jadhav AP, Cepko CL. A typology of photoreceptor gene expression patterns in the mouse. Proceedings of the National Academy of Sciences of the United States of America. 104: 12069-74. PMID 17620597 DOI: 10.1073/Pnas.0705465104  0.829
2007 Chen B, Cepko CL. Requirement of histone deacetylase activity for the expression of critical photoreceptor genes. Bmc Developmental Biology. 7: 78. PMID 17603891 DOI: 10.1186/1471-213X-7-78  0.46
2007 Viney TJ, Balint K, Hillier D, Siegert S, Boldogkoi Z, Enquist LW, Meister M, Cepko CL, Roska B. Local retinal circuits of melanopsin-containing ganglion cells identified by transsynaptic viral tracing. Current Biology : Cb. 17: 981-8. PMID 17524644 DOI: 10.1016/J.Cub.2007.04.058  0.83
2007 Trimarchi JM, Stadler MB, Roska B, Billings N, Sun B, Bartch B, Cepko CL. Molecular heterogeneity of developing retinal ganglion and amacrine cells revealed through single cell gene expression profiling. The Journal of Comparative Neurology. 502: 1047-65. PMID 17444492 DOI: 10.1002/Cne.21368  0.848
2007 Galante PA, Trimarchi J, Cepko CL, de Souza SJ, Ohno-Machado L, Kuo WP. Automatic correspondence of tags and genes (ACTG): a tool for the analysis of SAGE, MPSS and SBS data. Bioinformatics (Oxford, England). 23: 903-5. PMID 17277333 DOI: 10.1093/bioinformatics/btm023  0.319
2007 Punzo C, Cepko C. Cellular responses to photoreceptor death in the rd1 mouse model of retinal degeneration. Investigative Ophthalmology & Visual Science. 48: 849-57. PMID 17251487 DOI: 10.1167/iovs.05-1555  0.527
2007 Matsuda T, Cepko CL. Controlled expression of transgenes introduced by in vivo electroporation. Proceedings of the National Academy of Sciences of the United States of America. 104: 1027-32. PMID 17209010 DOI: 10.1073/pnas.0610155104  0.491
2006 Jadhav AP, Cho SH, Cepko CL. Notch activity permits retinal cells to progress through multiple progenitor states and acquire a stem cell property. Proceedings of the National Academy of Sciences of the United States of America. 103: 18998-9003. PMID 17148603 DOI: 10.1073/Pnas.0608155103  0.672
2006 Cho SH, Cepko CL. Wnt2b/beta-catenin-mediated canonical Wnt signaling determines the peripheral fates of the chick eye. Development (Cambridge, England). 133: 3167-77. PMID 16854977 DOI: 10.1242/dev.02474  0.428
2006 Young-Pearse TL, Ivic L, Kriegstein AR, Cepko CL. Characterization of mice with targeted deletion of glycine receptor alpha 2. Molecular and Cellular Biology. 26: 5728-34. PMID 16847326 DOI: 10.1128/Mcb.00237-06  0.729
2006 Wildner H, Müller T, Cho SH, Bröhl D, Cepko CL, Guillemot F, Birchmeier C. dILA neurons in the dorsal spinal cord are the product of terminal and non-terminal asymmetric progenitor cell divisions, and require Mash1 for their development. Development (Cambridge, England). 133: 2105-13. PMID 16690754 DOI: 10.1242/dev.02345  0.592
2006 Jadhav AP, Mason HA, Cepko CL. Notch 1 inhibits photoreceptor production in the developing mammalian retina. Development (Cambridge, England). 133: 913-23. PMID 16452096 DOI: 10.1242/Dev.02245  0.655
2006 Harpavat S, Cepko CL. RCAS-RNAi: a loss-of-function method for the developing chick retina. Bmc Developmental Biology. 6: 2. PMID 16426460 DOI: 10.1186/1471-213X-6-2  0.716
2005 Cepko CL. Effect of gene expression on cone survival in retinitis pigmentosa. Retina (Philadelphia, Pa.). 25: S21-S24. PMID 16374320 DOI: 10.1097/00006982-200512001-00008  0.436
2005 Sen J, Harpavat S, Peters MA, Cepko CL. Retinoic acid regulates the expression of dorsoventral topographic guidance molecules in the chick retina. Development (Cambridge, England). 132: 5147-59. PMID 16251210 DOI: 10.1242/Dev.02100  0.739
2005 Corbo JC, Cepko CL. A hybrid photoreceptor expressing both rod and cone genes in a mouse model of enhanced S-cone syndrome. Plos Genetics. 1: e11. PMID 16110338 DOI: 10.1371/journal.pgen.0010011  0.826
2005 Rowan S, Cepko CL. A POU factor binding site upstream of the Chx10 homeobox gene is required for Chx10 expression in subsets of retinal progenitor cells and bipolar cells. Developmental Biology. 281: 240-55. PMID 15893976 DOI: 10.1016/J.Ydbio.2005.02.023  0.742
2005 Young TL, Matsuda T, Cepko CL. The noncoding RNA taurine upregulated gene 1 is required for differentiation of the murine retina. Current Biology : Cb. 15: 501-12. PMID 15797018 DOI: 10.1016/j.cub.2005.02.027  0.445
2005 Schulte D, Peters MA, Sen J, Cepko CL. The rod photoreceptor pattern is set at the optic vesicle stage and requires spatially restricted cVax expression. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 2823-31. PMID 15772342 DOI: 10.1523/Jneurosci.2037-04.2005  0.707
2005 Morrow EM, Furukawa T, Raviola E, Cepko CL. Synaptogenesis and outer segment formation are perturbed in the neural retina of Crx mutant mice. Bmc Neuroscience. 6: 5. PMID 15676071 DOI: 10.1186/1471-2202-6-5  0.727
2005 Kim JS, Coon SL, Blackshaw S, Cepko CL, Møller M, Mukda S, Zhao WQ, Charlton CG, Klein DC. Methionine adenosyltransferase:adrenergic-cAMP mechanism regulates a daily rhythm in pineal expression. The Journal of Biological Chemistry. 280: 677-84. PMID 15504733 DOI: 10.1074/jbc.M408438200  0.515
2004 Rowan S, Chen CM, Young TL, Fisher DE, Cepko CL. Transdifferentiation of the retina into pigmented cells in ocular retardation mice defines a new function of the homeodomain gene Chx10. Development (Cambridge, England). 131: 5139-52. PMID 15459106 DOI: 10.1242/Dev.01300  0.751
2004 Cai L, Huang H, Blackshaw S, Liu JS, Cepko C, Wong WH. Clustering analysis of SAGE data using a Poisson approach. Genome Biology. 5: R51. PMID 15239836 DOI: 10.1186/Gb-2004-5-7-R51  0.566
2004 Blackshaw S, Harpavat S, Trimarchi J, Cai L, Huang H, Kuo WP, Weber G, Lee K, Fraioli RE, Cho SH, Yung R, Asch E, Ohno-Machado L, Wong WH, Cepko CL. Genomic analysis of mouse retinal development. Plos Biology. 2: E247. PMID 15226823 DOI: 10.1371/Journal.Pbio.0020247  0.839
2004 Rowan S, Cepko CL. Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter. Developmental Biology. 271: 388-402. PMID 15223342 DOI: 10.1016/J.Ydbio.2004.03.039  0.745
2004 Young TL, Cepko CL. A role for ligand-gated ion channels in rod photoreceptor development. Neuron. 41: 867-79. PMID 15046720 DOI: 10.1016/S0896-6273(04)00141-2  0.345
2004 Zhang J, Gray J, Wu L, Leone G, Rowan S, Cepko CL, Zhu X, Craft CM, Dyer MA. Rb regulates proliferation and rod photoreceptor development in the mouse retina. Nature Genetics. 36: 351-60. PMID 14991054 DOI: 10.1038/Ng1318  0.808
2004 Livesey FJ, Young TL, Cepko CL. An analysis of the gene expression program of mammalian neural progenitor cells. Proceedings of the National Academy of Sciences of the United States of America. 101: 1374-9. PMID 14734810 DOI: 10.1073/pnas.0307014101  0.739
2004 Pignatelli V, Cepko CL, Strettoi E. Inner retinal abnormalities in a mouse model of Leber's congenital amaurosis. The Journal of Comparative Neurology. 469: 351-9. PMID 14730587 DOI: 10.1002/Cne.11019  0.489
2004 Matsuda T, Cepko CL. Electroporation and RNA interference in the rodent retina in vivo and in vitro. Proceedings of the National Academy of Sciences of the United States of America. 101: 16-22. PMID 14603031 DOI: 10.1073/pnas.2235688100  0.508
2003 Harpavat S, Cepko CL. Thyroid hormone and retinal development: an emerging field. Thyroid : Official Journal of the American Thyroid Association. 13: 1013-9. PMID 14651785 DOI: 10.1089/105072503770867183  0.697
2003 Dyer MA, Livesey FJ, Cepko CL, Oliver G. Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina. Nature Genetics. 34: 53-8. PMID 12692551 DOI: 10.1038/ng1144  0.792
2003 Blackshaw S, Kuo WP, Park PJ, Tsujikawa M, Gunnersen JM, Scott HS, Boon WM, Tan SS, Cepko CL. MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues. Genome Biology. 4: R17. PMID 12620102 DOI: 10.1186/Gb-2003-4-3-R17  0.557
2003 Jin Z, Zhang J, Klar A, Chédotal A, Rao Y, Cepko CL, Bao ZZ. Irx4-mediated regulation of Slit1 expression contributes to the definition of early axonal paths inside the retina. Development (Cambridge, England). 130: 1037-48. PMID 12571096 DOI: 10.1242/dev.00326  0.604
2002 Blackshaw S, Cepko CL. Stem cells that know their place. Nature Neuroscience. 5: 1251-2. PMID 12447376 DOI: 10.1038/nn1202-1251  0.575
2002 Peters MA, Cepko CL. The dorsal-ventral axis of the neural retina is divided into multiple domains of restricted gene expression which exhibit features of lineage compartments. Developmental Biology. 251: 59-73. PMID 12413898 DOI: 10.1006/Dbio.2002.0791  0.638
2002 Chen CM, Cepko CL. The chicken RaxL gene plays a role in the initiation of photoreceptor differentiation. Development (Cambridge, England). 129: 5363-75. PMID 12403708 DOI: 10.1242/dev.00114  0.57
2002 Goh KL, Cai L, Cepko CL, Gertler FB. Ena/VASP proteins regulate cortical neuronal positioning. Current Biology : Cb. 12: 565-9. PMID 11937025 DOI: 10.1016/S0960-9822(02)00725-X  0.545
2002 Furukawa A, Koike C, Lippincott P, Cepko CL, Furukawa T. The mouse Crx 5'-upstream transgene sequence directs cell-specific and developmentally regulated expression in retinal photoreceptor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 1640-7. PMID 11880494 DOI: 10.1523/Jneurosci.22-05-01640.2002  0.569
2002 Bowne SJ, Sullivan LS, Blanton SH, Cepko CL, Blackshaw S, Birch DG, Hughbanks-Wheaton D, Heckenlively JR, Daiger SP. Mutations in the inosine monophosphate dehydrogenase 1 gene (IMPDH1) cause the RP10 form of autosomal dominant retinitis pigmentosa. Human Molecular Genetics. 11: 559-68. PMID 11875050 DOI: 10.1093/Hmg/11.5.559  0.589
2002 Szele FG, Chin HK, Rowlson MA, Cepko CL. Sox-9 and cDachsund-2 expression in the developing chick telencephalon. Mechanisms of Development. 112: 179-82. PMID 11850191 DOI: 10.1016/S0925-4773(01)00641-4  0.672
2002 Sharon D, Blackshaw S, Cepko CL, Dryja TP. Profile of the genes expressed in the human peripheral retina, macula, and retinal pigment epithelium determined through serial analysis of gene expression (SAGE). Proceedings of the National Academy of Sciences of the United States of America. 99: 315-20. PMID 11756676 DOI: 10.1073/pnas.012582799  0.659
2001 Blackshaw S, Fraioli RE, Furukawa T, Cepko CL. Comprehensive analysis of photoreceptor gene expression and the identification of candidate retinal disease genes. Cell. 107: 579-89. PMID 11733058 DOI: 10.1016/S0092-8674(01)00574-8  0.626
2001 Chang B, Smith RS, Peters M, Savinova OV, Hawes NL, Zabaleta A, Nusinowitz S, Martin JE, Davisson ML, Cepko CL, Hogan BL, John SW. Haploinsufficient Bmp4 ocular phenotypes include anterior segment dysgenesis with elevated intraocular pressure. Bmc Genetics. 2: 18. PMID 11722794 DOI: 10.1186/1471-2156-2-18  0.64
2001 Cepko CL. Tackling the brain's genetic complexity. Nature Neuroscience. 4: 1159-60. PMID 11687824 DOI: 10.1038/nn1101-1159  0.359
2001 Lu QR, Cai L, Rowitch D, Cepko CL, Stiles CD. Ectopic expression of Olig1 promotes oligodendrocyte formation and reduces neuronal survival in developing mouse cortex. Nature Neuroscience. 4: 973-4. PMID 11574831 DOI: 10.1038/nn718  0.51
2001 Dyer MA, Cepko CL. p27Kip1 and p57Kip2 regulate proliferation in distinct retinal progenitor cell populations. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 4259-71. PMID 11404411 DOI: 10.1523/Jneurosci.21-12-04259.2001  0.67
2001 Dyer MA, Cepko CL. Regulating proliferation during retinal development. Nature Reviews. Neuroscience. 2: 333-42. PMID 11331917 DOI: 10.1038/35072555  0.639
2001 Livesey FJ, Cepko CL. Vertebrate neural cell-fate determination: lessons from the retina. Nature Reviews. Neuroscience. 2: 109-18. PMID 11252990 DOI: 10.1038/35053522  0.715
2001 Bruneau BG, Bao ZZ, Fatkin D, Xavier-Neto J, Georgakopoulos D, Maguire CT, Berul CI, Kass DA, Kuroski-de Bold ML, de Bold AJ, Conner DA, Rosenthal N, Cepko CL, Seidman CE, Seidman JG. Cardiomyopathy in Irx4-deficient mice is preceded by abnormal ventricular gene expression. Molecular and Cellular Biology. 21: 1730-6. PMID 11238910 DOI: 10.1128/Mcb.21.5.1730-1736.2001  0.576
2001 Lin JC, Cai L, Cepko CL. The external granule layer of the developing chick cerebellum generates granule cells and cells of the isthmus and rostral hindbrain. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 21: 159-68. PMID 11150332 DOI: 10.1523/Jneurosci.21-01-00159.2001  0.59
2001 Dyer MA, Cepko CL. The p57Kip2 cyclin kinase inhibitor is expressed by a restricted set of amacrine cells in the rodent retina. The Journal of Comparative Neurology. 429: 601-14. PMID 11135238 DOI: 10.1002/1096-9861(20010122)429:4<601::AID-CNE7>3.0.CO;2-V  0.676
2000 Schulte D, Cepko CL. Two homeobox genes define the domain of EphA3 expression in the developing chick retina. Development (Cambridge, England). 127: 5033-45. PMID 11060230  0.519
2000 Cepko CL, Ryder E, Austin C, Golden J, Fields-Berry S, Lin J. Lineage analysis with retroviral vectors. Methods in Enzymology. 327: 118-45. PMID 11044979 DOI: 10.1016/S0076-6879(00)27272-8  0.703
2000 Dyer MA, Cepko CL. Control of Müller glial cell proliferation and activation following retinal injury. Nature Neuroscience. 3: 873-80. PMID 10966617 DOI: 10.1038/78774  0.692
2000 Sohoki MM, Browne SJ, Sullivan LS, Blackshaw S, Cepko CL, Payne AM, Bhattacharya SS, Khaliq S, Mehdi SQ, Birch DG, Harrison WR, Elder FF, Heckenlively JR, Daiger SP. Mutations in a new photoreceptor-pineal gene on 17p cause leber congenital amaurosis. Nat gen 2000;24:79-83 American Journal of Ophthalmology. 129: 834-5. PMID 10927016 DOI: 10.1016/S0002-9394(00)00517-1  0.525
2000 Dyer MA, Cepko CL. p57(Kip2) regulates progenitor cell proliferation and amacrine interneuron development in the mouse retina. Development (Cambridge, England). 127: 3593-605. PMID 10903183  0.619
2000 Liu W, Khare SL, Liang X, Peters MA, Liu X, Cepko CL, Xiang M. All Brn3 genes can promote retinal ganglion cell differentiation in the chick. Development (Cambridge, England). 127: 3237-47. PMID 10887080  0.7
2000 Cai L, Morrow EM, Cepko CL. Misexpression of basic helix-loop-helix genes in the murine cerebral cortex affects cell fate choices and neuronal survival. Development (Cambridge, England). 127: 3021-30. PMID 10862740  0.732
2000 Furukawa T, Mukherjee S, Bao ZZ, Morrow EM, Cepko CL. rax, Hes1, and notch1 promote the formation of Müller glia by postnatal retinal progenitor cells. Neuron. 26: 383-94. PMID 10839357 DOI: 10.1016/S0896-6273(00)81171-X  0.817
2000 Livesey FJ, Furukawa T, Steffen MA, Church GM, Cepko CL. Microarray analysis of the transcriptional network controlled by the photoreceptor homeobox gene Crx. Current Biology : Cb. 10: 301-10. PMID 10744971 DOI: 10.1016/S0960-9822(00)00379-1  0.685
2000 Belliveau MJ, Young TL, Cepko CL. Late retinal progenitor cells show intrinsic limitations in the production of cell types and the kinetics of opsin synthesis. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 20: 2247-54. PMID 10704500 DOI: 10.1523/Jneurosci.20-06-02247.2000  0.516
2000 Cepko C. Giving in to the blues. Nature Genetics. 24: 99-100. PMID 10655045 DOI: 10.1038/72887  0.311
2000 Chen CM, Cepko CL. Expression of Chx10 and Chx10-1 in the developing chicken retina. Mechanisms of Development. 90: 293-7. PMID 10640715 DOI: 10.1016/S0925-4773(99)00251-8  0.529
2000 Bruneau BG, Bao ZZ, Tanaka M, Schott JJ, Izumo S, Cepko CL, Seidman JG, Seidman CE. Cardiac expression of the ventricle-specific homeobox gene Irx4 is modulated by Nkx2-5 and dHand. Developmental Biology. 217: 266-77. PMID 10625552 DOI: 10.1006/Dbio.1999.9548  0.582
2000 Sohocki MM, Bowne SJ, Sullivan LS, Blackshaw S, Cepko CL, Payne AM, Bhattacharya SS, Khaliq S, Qasim Mehdi S, Birch DG, Harrison WR, Elder FF, Heckenlively JR, Daiger SP. Mutations in a new photoreceptor-pineal gene on 17p cause Leber congenital amaurosis. Nature Genetics. 24: 79-83. PMID 10615133 DOI: 10.1038/71732  0.526
1999 Schulte D, Furukawa T, Peters MA, Kozak CA, Cepko CL. Misexpression of the Emx-related homeobox genes cVax and mVax2 ventralizes the retina and perturbs the retinotectal map. Neuron. 24: 541-53. PMID 10595508 DOI: 10.1016/S0896-6273(00)81111-3  0.7
1999 Furukawa T, Morrow EM, Li T, Davis FC, Cepko CL. Retinopathy and attenuated circadian entrainment in Crx-deficient mice. Nature Genetics. 23: 466-70. PMID 10581037 DOI: 10.1038/70591  0.739
1999 Chen CM, Smith DM, Peters MA, Samson ME, Zitz J, Tabin CJ, Cepko CL. Production and design of more effective avian replication-incompetent retroviral vectors. Developmental Biology. 214: 370-84. PMID 10525341 DOI: 10.1006/Dbio.1999.9432  0.576
1999 Lin JC, Cepko CL. Biphasic dispersion of clones containing Purkinje cells and glia in the developing chick cerebellum. Developmental Biology. 211: 177-97. PMID 10395781 DOI: 10.1006/dbio.1999.9316  0.447
1999 Cepko CL. The roles of intrinsic and extrinsic cues and bHLH genes in the determination of retinal cell fates. Current Opinion in Neurobiology. 9: 37-46. PMID 10072376 DOI: 10.1016/S0959-4388(99)80005-1  0.544
1999 Bao ZZ, Bruneau BG, Seidman JG, Seidman CE, Cepko CL. Regulation of chamber-specific gene expression in the developing heart by Irx4. Science (New York, N.Y.). 283: 1161-4. PMID 10024241 DOI: 10.1126/Science.283.5405.1161  0.591
1999 Belliveau MJ, Cepko CL. Extrinsic and intrinsic factors control the genesis of amacrine and cone cells in the rat retina. Development (Cambridge, England). 126: 555-66. PMID 9876184  0.407
1999 Morrow EM, Furukawa T, Lee JE, Cepko CL. NeuroD regulates multiple functions in the developing neural retina in rodent. Development (Cambridge, England). 126: 23-36. PMID 9834183  0.76
1999 Livesey F, Gustincich S, Steffen M, Cheung V, Raviola E, Church G, Cepko C. Clustering cell types and identifying cell-type specific transcripts by gene expression profiling in single neurons Nature Genetics. 23: 59-59. DOI: 10.1038/14354  0.662
1998 Lin JC, Cepko CL. Granule cell raphes and parasagittal domains of Purkinje cells: complementary patterns in the developing chick cerebellum. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 9342-53. PMID 9801373 DOI: 10.1523/Jneurosci.18-22-09342.1998  0.47
1998 Morrow EM, Furukawa T, Cepko CL. Vertebrate photoreceptor cell development and disease. Trends in Cell Biology. 8: 353-8. PMID 9728396 DOI: 10.1016/S0962-8924(98)01341-5  0.718
1998 Ma C, Papermaster D, Cepko CL. A unique pattern of photoreceptor degeneration in cyclin D1 mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 95: 9938-43. PMID 9707579 DOI: 10.1073/Pnas.95.17.9938  0.45
1998 Cepko CL, Ryder E, Austin C, Golden J, Fields-Berry S, Lin J. Lineage analysis using retroviral vectors. Methods (San Diego, Calif.). 14: 393-406. PMID 9608510 DOI: 10.1006/Meth.1998.0594  0.674
1998 Morrow EM, Belliveau MJ, Cepko CL. Two phases of rod photoreceptor differentiation during rat retinal development. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 18: 3738-48. PMID 9570804 DOI: 10.1523/Jneurosci.18-10-03738.1998  0.75
1998 Szele FG, Cepko CL. The dispersion of clonally related cells in the developing chick telencephalon. Developmental Biology. 195: 100-13. PMID 9520328 DOI: 10.1006/dbio.1997.8725  0.708
1998 Cepko CL, Fields-Berry S, Ryder E, Austin C, Golden J. Lineage analysis using retroviral vectors. Current Topics in Developmental Biology. 36: 51-74. PMID 9342521 DOI: 10.1016/S0070-2153(08)60495-0  0.561
1997 Freund CL, Gregory-Evans CY, Furukawa T, Papaioannou M, Looser J, Ploder L, Bellingham J, Ng D, Herbrick JA, Duncan A, Scherer SW, Tsui LC, Loutradis-Anagnostou A, Jacobson SG, Cepko CL, et al. Cone-rod dystrophy due to mutations in a novel photoreceptor-specific homeobox gene (CRX) essential for maintenance of the photoreceptor. Cell. 91: 543-53. PMID 9390563 DOI: 10.1016/S0092-8674(00)80440-7  0.386
1997 Furukawa T, Morrow EM, Cepko CL. Crx, a novel otx-like homeobox gene, shows photoreceptor-specific expression and regulates photoreceptor differentiation. Cell. 91: 531-41. PMID 9390562 DOI: 10.1016/S0092-8674(00)80439-0  0.784
1997 Golden JA, Zitz JC, McFadden K, Cepko CL. Cell migration in the developing chick diencephalon. Development (Cambridge, England). 124: 3525-33. PMID 9342045  0.512
1997 Alexiades MR, Cepko CL. Subsets of retinal progenitors display temporally regulated and distinct biases in the fates of their progeny. Development (Cambridge, England). 124: 1119-31. PMID 9102299  0.478
1997 Furukawa T, Kozak CA, Cepko CL. rax, a novel paired-type homeobox gene, shows expression in the anterior neural fold and developing retina. Proceedings of the National Academy of Sciences of the United States of America. 94: 3088-93. PMID 9096350 DOI: 10.1073/pnas.94.7.3088  0.48
1997 Ezzeddine ZD, Yang X, DeChiara T, Yancopoulos G, Cepko CL. Postmitotic cells fated to become rod photoreceptors can be respecified by CNTF treatment of the retina. Development (Cambridge, England). 124: 1055-67. PMID 9056780  0.474
1997 Bao ZZ, Cepko CL. The expression and function of Notch pathway genes in the developing rat eye. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 17: 1425-34. PMID 9006984 DOI: 10.1523/Jneurosci.17-04-01425.1997  0.67
1996 Szele FG, Cepko CL. A subset of clones in the chick telencephalon arranged in rostrocaudal arrays. Current Biology : Cb. 6: 1685-90. PMID 8994834 DOI: 10.1016/S0960-9822(02)70793-8  0.705
1996 Alexiades MR, Cepko C. Quantitative analysis of proliferation and cell cycle length during development of the rat retina. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 205: 293-307. PMID 8850565 DOI: 10.1002/(SICI)1097-0177(199603)205:3<293::AID-AJA9>3.0.CO;2-D  0.477
1996 Yang X, Cepko CL. Flk-1, a receptor for vascular endothelial growth factor (VEGF), is expressed by retinal progenitor cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 6089-99. PMID 8815891 DOI: 10.1523/Jneurosci.16-19-06089.1996  0.773
1996 Cepko CL. The patterning and onset of opsin expression in vertebrate retinae. Current Opinion in Neurobiology. 6: 542-6. PMID 8794108 DOI: 10.1016/S0959-4388(96)80062-6  0.349
1996 Bruhn SL, Cepko CL. Development of the pattern of photoreceptors in the chick retina. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 16: 1430-9. PMID 8778294 DOI: 10.1523/Jneurosci.16-04-01430.1996  0.451
1996 Arnold-Aldea SA, Cepko CL. Dispersion patterns of clonally related cells during development of the hypothalamus. Developmental Biology. 173: 148-61. PMID 8575617 DOI: 10.1006/dbio.1996.0013  0.396
1996 Cepko CL, Austin CP, Yang X, Alexiades M, Ezzeddine D. Cell fate determination in the vertebrate retina. Proceedings of the National Academy of Sciences of the United States of America. 93: 589-95. PMID 8570600 DOI: 10.1073/Pnas.93.2.589  0.806
1996 Golden JA, Cepko CL. Clones in the chick diencephalon contain multiple cell types and siblings are widely dispersed. Development (Cambridge, England). 122: 65-78. PMID 8565854  0.515
1996 Golden JA, Zilz JC, Cepko CL. NON-RADIAL GLIAL DIRECTED MIGRATION OF NEURONAL PRECURSORS Journal of Neuropathology and Experimental Neurology. 55: 612. DOI: 10.1097/00005072-199605000-00041  0.494
1995 Austin CP, Feldman DE, Ida JA, Cepko CL. Vertebrate retinal ganglion cells are selected from competent progenitors by the action of Notch. Development (Cambridge, England). 121: 3637-50. PMID 8582277  0.654
1995 Golden JA, Fields-Berry SC, Cepko CL. Construction and characterization of a highly complex retroviral library for lineage analysis. Proceedings of the National Academy of Sciences of the United States of America. 92: 5704-8. PMID 7777573 DOI: 10.1073/pnas.92.12.5704  0.535
1994 Austin CP, Cepko CL. Retrovirus mediated gene transduction into the vertebrate CNS. Gene Therapy. 1: S6-9. PMID 8542405  0.498
1994 Ryder EF, Cepko CL. Migration patterns of clonally related granule cells and their progenitors in the developing chick cerebellum. Neuron. 12: 1011-28. PMID 8185941 DOI: 10.1016/0896-6273(94)90310-7  0.431
1994 Deitcher DL, Fekete DM, Cepko CL. Asymmetric expression of a novel homeobox gene in vertebrate sensory organs. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 486-98. PMID 7905512 DOI: 10.1523/Jneurosci.14-02-00486.1994  0.412
1994 Fekete DM, Perez-Miguelsanz J, Ryder EF, Cepko CL. Clonal analysis in the chicken retina reveals tangential dispersion of clonally related cells. Developmental Biology. 166: 666-82. PMID 7813785 DOI: 10.1006/Dbio.1994.1346  0.527
1994 Wu DK, Cepko CL. The stability of endogenous tyrosine hydroxylase protein in PC-12 cells differs from that expressed in mouse fibroblasts by gene transfer. Journal of Neurochemistry. 62: 863-72. PMID 7509376 DOI: 10.1046/J.1471-4159.1994.62030863.X  0.61
1993 Walsh C, Cepko CL. Clonal dispersion in proliferative layers of developing cerebral cortex. Nature. 362: 632-5. PMID 8464513 DOI: 10.1038/362632a0  0.629
1993 Fekete DM, Cepko CL. Replication-competent retroviral vectors encoding alkaline phosphatase reveal spatial restriction of viral gene expression/transduction in the chick embryo. Molecular and Cellular Biology. 13: 2604-13. PMID 8455633 DOI: 10.1128/Mcb.13.4.2604  0.408
1993 Fekete DM, Cepko CL. Retroviral infection coupled with tissue transplantation limits gene transfer in the chicken embryo. Proceedings of the National Academy of Sciences of the United States of America. 90: 2350-4. PMID 8384720 DOI: 10.1073/Pnas.90.6.2350  0.375
1993 Nirenberg S, Cepko C. Targeted ablation of diverse cell classes in the nervous system in vivo. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 3238-51. PMID 8340805 DOI: 10.1523/Jneurosci.13-08-03238.1993  0.762
1993 Yang X, Chung D, Cepko CL. Molecular cloning of the murine JAK1 protein tyrosine kinase and its expression in the mouse central nervous system. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 13: 3006-17. PMID 8331382 DOI: 10.1523/Jneurosci.13-07-03006.1993  0.759
1993 Cepko CL, Ryder EF, Austin CP, Walsh C, Fekete DM. Lineage analysis using retrovirus vectors. Methods in Enzymology. 225: 933-60. PMID 8231895 DOI: 10.1016/0076-6879(93)25059-B  0.685
1993 Sucher NJ, Brose N, Deitcher DL, Awobuluyi M, Gasic GP, Bading H, Cepko CL, Greenberg ME, Jahn R, Heinemann SF. Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells. The Journal of Biological Chemistry. 268: 22299-304. PMID 8226739  0.523
1993 Wu DK, Cepko CL. Development of dopaminergic neurons is insensitive to optic nerve section in the neonatal rat retina. Brain Research. Developmental Brain Research. 74: 253-60. PMID 8104745 DOI: 10.1016/0165-3806(93)90011-X  0.667
1993 Cepko CL. Retinal cell fate determination Progress in Retinal Research. 12: 1-12. DOI: 10.1016/0278-4327(93)90002-B  0.506
1992 Walsh C, Cepko CL. Widespread dispersion of neuronal clones across functional regions of the cerebral cortex. Science (New York, N.Y.). 255: 434-40. PMID 1734520 DOI: 10.1126/Science.1734520  0.604
1992 Snyder EY, Deitcher DL, Walsh C, Arnold-Aldea S, Hartwieg EA, Cepko CL. Multipotent neural cell lines can engraft and participate in development of mouse cerebellum. Cell. 68: 33-51. PMID 1732063 DOI: 10.1016/0092-8674(92)90204-P  0.75
1992 Fields-Berry SC, Halliday AL, Cepko CL. A recombinant retrovirus encoding alkaline phosphatase confirms clonal boundary assignment in lineage analysis of murine retina. Proceedings of the National Academy of Sciences of the United States of America. 89: 693-7. PMID 1731342 DOI: 10.1073/Pnas.89.2.693  0.449
1992 Halliday AL, Cepko CL. Generation and migration of cells in the developing striatum. Neuron. 9: 15-26. PMID 1632968 DOI: 10.1016/0896-6273(92)90216-Z  0.433
1992 Guillemot F, Cepko CL. Retinal fate and ganglion cell differentiation are potentiated by acidic FGF in an in vitro assay of early retinal development. Development (Cambridge, England). 114: 743-54. PMID 1377624  0.412
1991 Misson JP, Austin CP, Takahashi T, Cepko CL, Caviness VS. The alignment of migrating neural cells in relation to the murine neopallial radial glial fiber system. Cerebral Cortex (New York, N.Y. : 1991). 1: 221-9. PMID 1668365  0.506
1990 Ryder EF, Snyder EY, Cepko CL. Establishment and characterization of multipotent neural cell lines using retrovirus vector-mediated oncogene transfer. Journal of Neurobiology. 21: 356-75. PMID 2307979 DOI: 10.1002/Neu.480210209  0.613
1990 Walsh C, Cepko CL. Cell lineage and cell migration in the developing cerebral cortex. Experientia. 46: 940-7. PMID 2209803 DOI: 10.1007/BF01939387  0.464
1990 Turner DL, Snyder EY, Cepko CL. Lineage-independent determination of cell type in the embryonic mouse retina. Neuron. 4: 833-45. PMID 2163263 DOI: 10.1016/0896-6273(90)90136-4  0.74
1990 Cepko CL, Austin CP, Walsh C, Ryder EF, Halliday A, Fields-Berry S. Studies of cortical development using retrovirus vectors. Cold Spring Harbor Symposia On Quantitative Biology. 55: 265-78. PMID 2132820 DOI: 10.1101/Sqb.1990.055.01.029  0.652
1990 Austin CP, Cepko CL. Cellular migration patterns in the developing mouse cerebral cortex. Development (Cambridge, England). 110: 713-32. PMID 2088716  0.501
1989 Cepko CL. Immortalization of neural cells via retrovirus-mediated oncogene transduction. Annual Review of Neuroscience. 12: 47-65. PMID 2648957 DOI: 10.1146/annurev.ne.12.030189.000403  0.421
1989 Cepko C. Immortalization of neural cells via oncogene transduction. Trends in Neurosciences. 11: 6-8. PMID 2469155 DOI: 10.1016/0166-2236(88)90039-2  0.416
1988 Walsh C, Cepko CL. Clonally related cortical cells show several migration patterns. Science (New York, N.Y.). 241: 1342-5. PMID 3137660 DOI: 10.1126/SCIENCE.3137660  0.626
1987 Turner DL, Cepko CL. A common progenitor for neurons and glia persists in rat retina late in development. Nature. 328: 131-6. PMID 3600789 DOI: 10.1038/328131a0  0.605
1987 Bergh ML, Cepko CL, Wolf D, Robbins PW. Expression of the Saccharomyces cerevisiae glycoprotein invertase in mouse fibroblasts: glycosylation, secretion, and enzymatic activity. Proceedings of the National Academy of Sciences of the United States of America. 84: 3570-4. PMID 3295866 DOI: 10.1073/Pnas.84.11.3570  0.34
1987 Price J, Turner D, Cepko C. Lineage analysis in the vertebrate nervous system by retrovirus-mediated gene transfer Proceedings of the National Academy of Sciences of the United States of America. 84: 156-160. PMID 3099292 DOI: 10.1073/PNAS.84.1.156  0.569
1986 Choudary PV, Barranger JA, Tsuji S, Mayor J, LaMarca ME, Cepko CL, Mulligan RC, Ginns EI. Retrovirus-mediated transfer of the human glucocerebrosidase gene to Gaucher fibroblasts. Molecular Biology & Medicine. 3: 293-9. PMID 3736391  0.641
1986 Jat PS, Cepko CL, Mulligan RC, Sharp PA. Recombinant retroviruses encoding simian virus 40 large T antigen and polyomavirus large and middle T antigens. Molecular and Cellular Biology. 6: 1204-17. PMID 3023876 DOI: 10.1128/Mcb.6.4.1204  0.734
1985 Roberts BE, Miller JS, Kimelman D, Cepko CL, Lemischka IR, Mulligan RC. Individual adenovirus type 5 early region 1A gene products elicit distinct alterations of cellular morphology and gene expression. Journal of Virology. 56: 404-13. PMID 4057356 DOI: 10.1128/Jvi.56.2.404-413.1985  0.775
1984 Cepko CL, Roberts BE, Mulligan RC. Construction and applications of a highly transmissible murine retrovirus shuttle vector. Cell. 37: 1053-62. PMID 6331674 DOI: 10.1016/0092-8674(84)90440-9  0.632
1983 Cepko CL, Sharp PA. Analysis of Ad5 hexon and 100K ts mutants using conformation-specific monoclonal antibodies. Virology. 129: 137-54. PMID 6612996 DOI: 10.1016/0042-6822(83)90402-6  0.575
1983 Cepko CL, Sharp PA. Aberrant distribution of human adenovirus type 2 late proteins in monkey kidney cells. Journal of Virology. 46: 302-6. PMID 6402607 DOI: 10.1128/Jvi.46.1.302-306.1983  0.631
1983 Cepko CL, Whetstone CA, Sharp PA. Adenovirus hexon monoclonal antibody that is group specific and potentially useful as a diagnostic reagent. Journal of Clinical Microbiology. 17: 360-4. PMID 6339552 DOI: 10.1128/Jcm.17.2.360-364.1983  0.544
1983 Horowitz M, Cepko CL, Sharp PA. Expression of chimeric genes in the early region of SV40. Journal of Molecular and Applied Genetics. 2: 147-59. PMID 6192195  0.585
1982 Cepko CL, Sharp PA. Assembly of adenovirus major capsid protein is mediated by a nonvirion protein. Cell. 31: 407-15. PMID 7159928 DOI: 10.1016/0092-8674(82)90134-9  0.543
1981 Cepko CL, Changelian PS, Sharp PA. Immunoprecipitation with two-dimensional pools as a hybridoma screening technique: production and characterization of monoclonal antibodies against adenovirus 2 proteins. Virology. 110: 385-401. PMID 7222481 DOI: 10.1016/0042-6822(81)90069-6  0.57
1981 Ricciardi RP, Jones RL, Cepko CL, Sharp PA, Roberts BE. Expression of early adenovirus genes requires a viral encoded acidic polypeptide. Proceedings of the National Academy of Sciences of the United States of America. 78: 6121-5. PMID 6947217 DOI: 10.1073/pnas.78.10.6121  0.609
1981 Cepko CL, Hansen U, Handa H, Sharp PA. Sequential transcription-translation of simian virus 40 by using mammalian cell extracts. Molecular and Cellular Biology. 1: 919-31. PMID 6287212 DOI: 10.1128/Mcb.1.10.919  0.636
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