| Year |
Citation |
Score |
| 2022 |
Hoffman MJ, Takizawa A, Jensen ES, Schilling R, Grzybowski M, Geurts AM, Dwinell MR. Btg2 mutation induces renal injury and impairs blood pressure control in female rats. Physiological Genomics. PMID 35503009 DOI: 10.1152/physiolgenomics.00167.2021 |
0.325 |
|
| 2020 |
Mehrotra P, Ullah MM, Collett JA, Myers SL, Dwinell MR, Geurts AM, Basile DP. Mutation of RORγT reveals a role for Th17 cells in both injury and recovery from renal ischemia reperfusion injury. American Journal of Physiology. Renal Physiology. PMID 32924545 DOI: 10.1152/Ajprenal.00187.2020 |
0.353 |
|
| 2020 |
Chen YG, Ciecko AE, Khaja S, Grzybowski M, Geurts AM, Lieberman SM. UBASH3A deficiency accelerates type 1 diabetes development and enhances salivary gland inflammation in NOD mice. Scientific Reports. 10: 12019. PMID 32694640 DOI: 10.1038/S41598-020-68956-6 |
0.313 |
|
| 2020 |
Alexeyev M, Geurts AM, Annamdevula NS, Francis CM, Leavesley SJ, Rich TC, Taylor MS, Lin MT, Balczon R, Knighten JM, Alvarez DF, Stevens T. Development of an endothelial cell restricted transgenic reporter rat:A resource for physiological studies of vascular biology. American Journal of Physiology. Heart and Circulatory Physiology. PMID 32589443 DOI: 10.1152/Ajpheart.00276.2020 |
0.361 |
|
| 2020 |
Kitagawa A, Kizub I, Jacob C, Michael K, D'Alessandro A, Reisz JA, Grzybowski M, Geurts AM, Rocic P, Gupte R, Miano JM, Gupte SA. CRISPR-Mediated Single Nucleotide Polymorphism Modeling in Rats Reveals Insight Into Reduced Cardiovascular Risk Associated With Mediterranean Variant. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA12014. PMID 32507041 DOI: 10.1161/Hypertensionaha.120.14772 |
0.363 |
|
| 2020 |
Prokop JW, Chhetri SB, van Veen JE, Chen X, Underwood AC, Uhl K, Dwinell MR, Geurts AM, Correa SM, Arnold AP. Transcriptional analysis of the multiple Sry genes and developmental program at the onset of testis differentiation in the rat. Biology of Sex Differences. 11: 28. PMID 32398044 DOI: 10.1186/S13293-020-00305-8 |
0.38 |
|
| 2020 |
Exner EC, Geurts AM, Hoffmann BR, Casati M, Stodola T, Dsouza NR, Zimmermann M, Lombard JH, Greene AS. Interaction between Mas1 and AT1RA contributes to enhancement of skeletal muscle angiogenesis by angiotensin-(1-7) in Dahl salt-sensitive rats. Plos One. 15: e0232067. PMID 32324784 DOI: 10.1371/Journal.Pone.0232067 |
0.334 |
|
| 2020 |
Johnston JG, Speed JS, Becker BK, Kasztan M, Soliman RH, Rhoads MK, Tao B, Jin C, Geurts AM, Hyndman KA, Pollock JS, Pollock DM. Diurnal Control of Blood Pressure Is Uncoupled From Sodium Excretion. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11913. PMID 32306766 DOI: 10.1161/Hypertensionaha.119.13908 |
0.325 |
|
| 2020 |
Fan F, Geurts AM, Pabbidi MR, Ge Y, Zhang C, Wang S, Liu Y, Gao W, Guo Y, Li L, He X, Lv W, Muroya Y, Hirata T, Prokop J, et al. A Mutation in -Adducin Impairs Autoregulation of Renal Blood Flow and Promotes the Development of Kidney Disease. Journal of the American Society of Nephrology : Jasn. PMID 32029431 DOI: 10.1681/Asn.2019080784 |
0.318 |
|
| 2020 |
Guo H, Xu D, Kuroki M, Lu Z, Xu X, Geurts A, Osborn JW, Chen Y. Kidney injury, arterial hypertension and left ventricular hypertrophy in rats with loss of function mutation of SOD3. Free Radical Biology & Medicine. PMID 31972339 DOI: 10.1016/J.Freeradbiomed.2020.01.023 |
0.368 |
|
| 2020 |
Shi Q, Mattson JG, Fahs SA, Geurts AM, Weiler H, Montgomery RR. The severe spontaneous bleeding phenotype in a novel hemophilia A rat model is rescued by platelet FVIII expression. Blood Advances. 4: 55-65. PMID 31899798 DOI: 10.1182/Bloodadvances.2019000944 |
0.341 |
|
| 2020 |
Hoffman M, Takizawa A, Jensen E, Schilling R, Grzybowski M, Geurts AM, Dwinell MR. Abstract P124: Blood Pressure Characterization In Btg2 Mutant Rat Hypertension. 76. DOI: 10.1161/Hyp.76.Suppl_1.P124 |
0.318 |
|
| 2020 |
Dwinell MR, Takizawa A, Lazcares L, Schilling R, Hoffman M, Geurts A, Shimoyama M. Hybrid Rat Diversity Program (HRDP): A rat resource for mapping complex traits The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03705 |
0.307 |
|
| 2020 |
Kumar V, Geurts A, Kurth T, Zheleznova NN, Yang C, Cowley AW. Nox4‐mTORC1 connection in salt‐induced hypertension and kidney injury in Dahl S rats The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03536 |
0.318 |
|
| 2020 |
Zheleznova NN, Terashvili M, Bullis J, Stumpf M, Nguyen L, Geurts A, Lombard JH. Blood Pressure, Vascular Reactivity, and SOD Expression/Activity in Mas1 Receptor Knockout Rats in the Dahl Salt‐Sensitive Genetic Background The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03386 |
0.335 |
|
| 2019 |
Rasmussen SA, Daenzer JMI, MacWilliams JA, Head ST, Williams M, Geurts AM, Schroeder J, Weinshenker D, Fridovich-Keil JL. A GALT-null rat model of classic galactosemia mimics relevant patient outcomes and reveals tissue-specific and longitudinal differences in galactose metabolism. Journal of Inherited Metabolic Disease. PMID 31845342 DOI: 10.1002/Jimd.12205 |
0.329 |
|
| 2019 |
Arkhipov SN, Potter DL, Geurts AM, Pavlov TS. Knockout of purinergic receptor attenuates cyst growth in a rat model of ARPKD. American Journal of Physiology. Renal Physiology. PMID 31630543 DOI: 10.1152/Ajprenal.00395.2019 |
0.347 |
|
| 2019 |
Olson RJ, Hopp K, Wells H, Smith JM, Furtado J, Constans MM, Escobar DL, Geurts AM, Torres VE, Harris PC. Synergistic Genetic Interactions between and Result in an ARPKD-Like Phenotype in Murine Models. Journal of the American Society of Nephrology : Jasn. PMID 31427367 DOI: 10.1681/Asn.2019020150 |
0.323 |
|
| 2019 |
Xue H, Geurts AM, Usa K, Wang F, Lin Y, Phillips J, Henderson L, Baker MA, Tian Z, Liang M. Fumarase Overexpression Abolishes Hypertension Attributable to endothelial NO synthase Haploinsufficiency in Dahl Salt-Sensitive Rats. Hypertension (Dallas, Tex. : 1979). HYPERTENSIONAHA11912. PMID 31230549 DOI: 10.1161/Hypertensionaha.119.12723 |
0.388 |
|
| 2019 |
Yu FPS, Molino S, Sikora J, Rasmussen S, Rybova J, Tate E, Geurts AM, Turner PV, Mckillop WM, Medin JA. Hepatic pathology and altered gene transcription in a murine model of acid ceramidase deficiency. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 31186526 DOI: 10.1038/S41374-019-0271-4 |
0.303 |
|
| 2019 |
Zhang C, He X, Murphy SR, Zhang H, Wang S, Ge Y, Gao W, Williams JM, Geurts AM, Roman RJ, Fan F. Knockout of Dual-Specificity Protein Phosphatase 5 Protects Against Hypertension-induced Renal Injury. The Journal of Pharmacology and Experimental Therapeutics. PMID 31118214 DOI: 10.1124/Jpet.119.258954 |
0.334 |
|
| 2019 |
Nasci VL, Geurts A, Kriegel AJ. Abstract 093: Novel Mir-21-5p-/- Rat Model Exhibits Protection Against Chronic Kidney Disease Associated Cardiac Dysfunction Hypertension. 74. DOI: 10.1161/Hyp.74.Suppl_1.093 |
0.332 |
|
| 2018 |
Presa M, Racine JJ, Dwyer JR, Lamont DJ, Ratiu JJ, Sarsani VK, Chen YG, Geurts A, Schmitz I, Stearns T, Allocco J, Chapman HD, Serreze DV. A Hypermorphic Allele Contributes to Impaired Thymic Deletion of Autoreactive Diabetogenic CD8 T Cells in NOD Mice. Journal of Immunology (Baltimore, Md. : 1950). PMID 30127089 DOI: 10.4049/Jimmunol.1800465 |
0.306 |
|
| 2018 |
Xue H, Zhang G, Geurts AM, Usa K, Jensen DM, Liu Y, Widlansky ME, Liang M. Tissue-specific effects of targeted mutation of Mir29b1 in rats. Ebiomedicine. PMID 30120082 DOI: 10.1016/J.Ebiom.2018.08.016 |
0.326 |
|
| 2018 |
Spires D, Ilatovskaya DV, Levchenko V, North PE, Geurts AM, Palygin O, Staruschenko A. The protective role of Trpc6 knockout in the progression of diabetic kidney disease. American Journal of Physiology. Renal Physiology. PMID 29923767 DOI: 10.1152/Ajprenal.00155.2018 |
0.351 |
|
| 2018 |
Siebers EM, Choi MJ, Tinklenberg JA, Beatka MJ, Ayres S, Meng H, Helbling DC, Takizawa A, Bennett B, Garces AM, Dias Duarte Machado LG, Dimmock D, Dwinell MR, Geurts AM, Lawlor MW. Sdha+/- Rats Display Minimal Muscle Pathology Without Significant Behavioral or Biochemical Abnormalities. Journal of Neuropathology and Experimental Neurology. PMID 29850869 DOI: 10.1093/Jnen/Nly042 |
0.364 |
|
| 2018 |
Ilatovskaya DV, Blass G, Palygin O, Levchenko V, Pavlov TS, Grzybowski MN, Winsor K, Shuyskiy LS, Geurts AM, Cowley AW, Birnbaumer L, Staruschenko A. A NOX4/TRPC6 Pathway in Podocyte Calcium Regulation and Renal Damage in Diabetic Kidney Disease. Journal of the American Society of Nephrology : Jasn. PMID 29793963 DOI: 10.1681/Asn.2018030280 |
0.337 |
|
| 2018 |
Stodola TJ, Liu P, Liu Y, Vallejos A, Geurts AM, Greene AS, Liang M. Genome-wide map of proximity linkage to renin proximal promoter in rat. Physiological Genomics. PMID 29521603 DOI: 10.1152/Physiolgenomics.00132.2017 |
0.366 |
|
| 2018 |
Prokop JW, Yeo NC, Ottmann C, Chhetri SB, Florus KL, Ross EJ, Sosonkina N, Link BA, Freedman BI, Coppola CJ, McDermott-Roe C, Leysen S, Milroy LG, Meijer FA, Geurts AM, et al. Characterization of Coding/Noncoding Variants forin Patients with CKD. Journal of the American Society of Nephrology : Jasn. PMID 29476007 DOI: 10.1681/Asn.2017080856 |
0.315 |
|
| 2018 |
Geurts AM, Schilling R, Grzybowski M, Temple A, Zappa A, Lazcares L, Niebuhr J, Kalloway S, Foeckler J, Takizawa A, Dwinell MR. Abstract P292: Gene Editing Rat Resource Center: Rat Models for Heart, Lung, Blood, and Sleep Disorder Studies Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P292 |
0.353 |
|
| 2018 |
Becker BK, Chen D, Colson JC, Jin C, Cowley AW, Geurts A, Young ME, Pollock JS, Pollock DM. Abstract P217: Evidence for Impaired Diurnal Cardio-Vagal Tone Due to p67phox in Dahl Salt-Sensitive Rats Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.P217 |
0.321 |
|
| 2018 |
Xue H, Zhang G, Geurts AM, Usa K, Jensen DM, Liu Y, Liang M. Abstract 054: Tissue-Specific Effects of Targeted Mutation of
Mir29b1
in Rats Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.054 |
0.345 |
|
| 2018 |
Dwinell M, Lazar J, Grzybowski M, Schilling R, Varagic J, Geurts A, Ferrario C. A16670 Development of a Transgenic Rat Expressing the Human Chymase Gene to Study Human Cardiovascular Disease Journal of Hypertension. 36: e87-e88. DOI: 10.1097/01.Hjh.0000548347.26465.Fc |
0.347 |
|
| 2017 |
Lukaszewicz KM, Durand MJ, Priestley JRC, Schmidt JR, Allen LA, Geurts AM, Lombard JH. Evaluation of Vascular Control Mechanisms Utilizing Video Microscopy of Isolated Resistance Arteries of Rats. Journal of Visualized Experiments : Jove. PMID 29286398 DOI: 10.3791/56133 |
0.353 |
|
| 2017 |
Palygin O, Ilatovskaya DV, Levchenko V, Endres BT, Geurts AM, Staruschenko A. Nitric oxide production by glomerular podocytes. Nitric Oxide : Biology and Chemistry. PMID 29128399 DOI: 10.1016/J.Niox.2017.11.005 |
0.33 |
|
| 2017 |
Palygin O, Levchenko V, Ilatovskaya DV, Pavlov TS, Pochynyuk OM, Jacob HJ, Geurts AM, Hodges MR, Staruschenko A. Essential role of Kir5.1 channels in renal salt handling and blood pressure control. Jci Insight. 2. PMID 28931751 DOI: 10.1172/Jci.Insight.92331 |
0.345 |
|
| 2017 |
Usa K, Liu Y, Geurts AM, Cheng Y, Lazar J, Baker MA, Grzybowski M, He Y, Tian Z, Liang M. Elevation of Fumarase Attenuates Hypertension and can Result from a Nonsynonymous Sequence Variation or Increased Expression Depending on Rat Strain. Physiological Genomics. physiolgenomics.0006. PMID 28754823 DOI: 10.1152/Physiolgenomics.00063.2017 |
0.392 |
|
| 2017 |
Endres BT, Sandoval RM, Rhodes GJ, Campos-Bilderback SB, Kamocka MM, McDermott-Roe C, Staruschenko A, Molitoris BA, Geurts AM, Palygin O. Intravital Imaging of the Kidney in a Rat Model of Salt-Sensitive Hypertension. American Journal of Physiology. Renal Physiology. ajprenal.00466.2016. PMID 28404591 DOI: 10.1152/Ajprenal.00466.2016 |
0.347 |
|
| 2017 |
Mitzelfelt KA, McDermott-Roe C, Grzybowski MN, Marquez M, Kuo CT, Riedel M, Lai S, Choi MJ, Kolander KD, Helbling D, Dimmock DP, Battle MA, Jou CJ, Tristani-Firouzi M, Verbsky JW, ... ... Geurts AM, et al. Efficient Precision Genome Editing in iPSCs via Genetic Co-targeting with Selection. Stem Cell Reports. PMID 28238794 DOI: 10.1016/J.Stemcr.2017.01.021 |
0.314 |
|
| 2016 |
Aitman T, Dhillon P, Geurts AM. A RATional choice for translational research? Disease Models & Mechanisms. 9: 1069-1072. PMID 27736742 DOI: 10.1242/Dmm.027706 |
0.368 |
|
| 2016 |
McPherson KC, Taylor L, Johnson AC, Didion SP, Geurts AM, Garrett MR, Williams JM. Early development of podocyte injury independent of hyperglycemia and elevations in arterial pressure in non-diabetic obese Dahl SS leptin receptor mutant rats. American Journal of Physiology. Renal Physiology. ajprenal.00590.2015. PMID 27465994 DOI: 10.1152/Ajprenal.00590.2015 |
0.328 |
|
| 2016 |
Miller B, Palygin O, Rufanova VA, Chong A, Lazar J, Jacob HJ, Mattson D, Roman RJ, Williams JM, Cowley AW, Geurts AM, Staruschenko A, Imig JD, Sorokin A. p66Shc regulates renal vascular tone in hypertension-induced nephropathy. The Journal of Clinical Investigation. PMID 27270176 DOI: 10.1172/Jci75079 |
0.323 |
|
| 2016 |
Mitzelfelt KA, Limphong P, Choi MJ, Kondrat FD, Lai S, Kolander KD, Kwok WM, Dai Q, Grzybowski MN, Zhang H, Taylor GM, Lui Q, Thao MT, Hudson JA, Barresi R, ... ... Geurts AM, et al. Human 343delT HSPB5 Chaperone associated with Early-onset Skeletal Myopathy causes Defects in Protein Solubility. The Journal of Biological Chemistry. PMID 27226619 DOI: 10.1074/Jbc.M116.730481 |
0.32 |
|
| 2016 |
Kuijk EW, Rasmussen S, Blokzijl F, Huch M, Gehart H, Toonen P, Begthel H, Clevers H, Geurts AM, Cuppen E. Generation and characterization of rat liver stem cell lines and their engraftment in a rat model of liver failure. Scientific Reports. 6: 22154. PMID 26915950 DOI: 10.1038/Srep22154 |
0.314 |
|
| 2016 |
Rubattu S, Di Castro S, Schulz H, Geurts AM, Cotugno M, Bianchi F, Maatz H, Hummel O, Falak S, Stanzione R, Marchitti S, Scarpino S, Giusti B, Kura A, Gensini GF, et al. Ndufc2 Gene Inhibition Is Associated With Mitochondrial Dysfunction and Increased Stroke Susceptibility in an Animal Model of Complex Human Disease. Journal of the American Heart Association. 5. PMID 26888427 DOI: 10.1161/Jaha.115.002701 |
0.313 |
|
| 2016 |
Kaplan K, Echert AE, Massat B, Puissant MM, Palygin O, Geurts AM, Hodges MR. Chronic central serotonin depletion attenuates ventilation and body temperature in young but not adult Tph2 knockout rats. Journal of Applied Physiology (Bethesda, Md. : 1985). jap.01015.2015. PMID 26869713 DOI: 10.1152/Japplphysiol.01015.2015 |
0.307 |
|
| 2016 |
Priestley JR, Kautenburg KE, Casati MC, Endres BT, Geurts AM, Lombard JH. The NRF2 knockout rat: a new animal model to study endothelial dysfunction, oxidant stress, and microvascular rarefaction. American Journal of Physiology. Heart and Circulatory Physiology. 310: H478-87. PMID 26637559 DOI: 10.1152/Ajpheart.00586.2015 |
0.367 |
|
| 2015 |
Cowley AW, Yang C, Zheleznova NN, Staruschenko A, Kurth T, Rein L, Kumar V, Sadovnikov K, Dayton A, Hoffman M, Ryan RP, Skelton MM, Salehpour F, Ranji M, Geurts A. Evidence of the Importance of Nox4 in Production of Hypertension in Dahl Salt-Sensitive Rats. Hypertension. PMID 26644237 DOI: 10.1161/Hypertensionaha.115.06280 |
0.404 |
|
| 2015 |
Cowley AW, Yang C, Kumar V, Lazar J, Jacob H, Geurts AM, Liu P, Dayton A, Kurth T, Liang M. PAPPA2 IS LINKED TO SALT-SENSITIVE HYPERTENSION IN DAHL S RATS. Physiological Genomics. physiolgenomics.0009. PMID 26534937 DOI: 10.1152/Physiolgenomics.00097.2015 |
0.4 |
|
| 2015 |
Nayak S, Khan MA, Wan TC, Pei H, Linden J, Dwinell MR, Geurts AM, Imig JD, Auchampach JA. Characterization of Dahl salt-sensitive rats with genetic disruption of the A2B adenosine receptor gene: implications for A2B adenosine receptor signaling during hypertension. Purinergic Signalling. PMID 26385692 DOI: 10.1007/S11302-015-9470-7 |
0.393 |
|
| 2015 |
Wang F, Zhang G, Lu Z, Geurts AM, Usa K, Jacob HJ, Cowley AW, Wang N, Liang M. Antithrombin III/SerpinC1 insufficiency exacerbates renal ischemia/reperfusion injury. Kidney International. PMID 26108065 DOI: 10.1038/Ki.2015.176 |
0.306 |
|
| 2015 |
Holditch SJ, Schreiber CA, Nini R, Tonne JM, Peng KW, Geurts A, Jacob HJ, Burnett JC, Cataliotti A, Ikeda Y. B-Type Natriuretic Peptide Deletion Leads to Progressive Hypertension, Associated Organ Damage, and Reduced Survival: Novel Model for Human Hypertension. Hypertension. 66: 199-210. PMID 26063669 DOI: 10.1161/Hypertensionaha.115.05610 |
0.375 |
|
| 2015 |
Flister MJ, Prokop JW, Lazar J, Shimoyama M, Dwinell M, Geurts A. 2015 Guidelines for Establishing Genetically Modified Rat Models for Cardiovascular Research. Journal of Cardiovascular Translational Research. 8: 269-77. PMID 25920443 DOI: 10.1007/S12265-015-9626-4 |
0.37 |
|
| 2015 |
Rudemiller NP, Lund H, Priestley JR, Endres BT, Prokop JW, Jacob HJ, Geurts AM, Cohen EP, Mattson DL. Mutation of SH2B3 (LNK), a genome-wide association study candidate for hypertension, attenuates Dahl salt-sensitive hypertension via inflammatory modulation. Hypertension. 65: 1111-7. PMID 25776069 DOI: 10.1161/Hypertensionaha.114.04736 |
0.372 |
|
| 2015 |
Fan F, Geurts AM, Murphy SR, Pabbidi MR, Jacob HJ, Roman RJ. Impaired myogenic response and autoregulation of cerebral blood flow is rescued in CYP4A1 transgenic Dahl salt-sensitive rat. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 308: R379-90. PMID 25540098 DOI: 10.1152/Ajpregu.00256.2014 |
0.365 |
|
| 2015 |
Geurts AM, Mattson DL, Liu P, Cabacungan E, Skelton MM, Kurth TM, Yang C, Endres BT, Klotz J, Liang M, Cowley AW. Maternal diet during gestation and lactation modifies the severity of salt-induced hypertension and renal injury in Dahl salt-sensitive rats. Hypertension. 65: 447-55. PMID 25452472 DOI: 10.1161/Hypertensionaha.114.04179 |
0.366 |
|
| 2014 |
Park AK, Liegel RP, Ronchetti A, Ebert AD, Geurts A, Sidjanin DJ. Targeted disruption of Tbc1d20 with zinc-finger nucleases causes cataracts and testicular abnormalities in mice. Bmc Genetics. 15: 135. PMID 25476608 DOI: 10.1186/S12863-014-0135-2 |
0.311 |
|
| 2014 |
Fan F, Geurts AM, Pabbidi MR, Smith SV, Harder DR, Jacob H, Roman RJ. Zinc-finger nuclease knockout of dual-specificity protein phosphatase-5 enhances the myogenic response and autoregulation of cerebral blood flow in FHH.1BN rats. Plos One. 9: e112878. PMID 25397684 DOI: 10.1371/Journal.Pone.0112878 |
0.415 |
|
| 2014 |
Endres BT, Priestley JR, Palygin O, Flister MJ, Hoffman MJ, Weinberg BD, Grzybowski M, Lombard JH, Staruschenko A, Moreno C, Jacob HJ, Geurts AM. Mutation of Plekha7 attenuates salt-sensitive hypertension in the rat. Proceedings of the National Academy of Sciences of the United States of America. 111: 12817-22. PMID 25136115 DOI: 10.1073/Pnas.1410745111 |
0.381 |
|
| 2014 |
Jin C, Sun J, Stilphen CA, Smith SM, Ocasio H, Bermingham B, Darji S, Guha A, Patel R, Geurts AM, Jacob HJ, Lambert NA, O'Connor PM. HV1 acts as a sodium sensor and promotes superoxide production in medullary thick ascending limb of Dahl salt-sensitive rats. Hypertension. 64: 541-50. PMID 24935944 DOI: 10.1161/Hypertensionaha.114.03549 |
0.383 |
|
| 2014 |
Ivics Z, Garrels W, Mátés L, Yau TY, Bashir S, Zidek V, Landa V, Geurts A, Pravenec M, Rülicke T, Kues WA, Izsvák Z. Germline transgenesis in pigs by cytoplasmic microinjection of Sleeping Beauty transposons. Nature Protocols. 9: 810-27. PMID 24625780 DOI: 10.1038/Nprot.2014.010 |
0.338 |
|
| 2014 |
Ivics Z, Mátés L, Yau TY, Landa V, Zidek V, Bashir S, Hoffmann OI, Hiripi L, Garrels W, Kues WA, Bösze Z, Geurts A, Pravenec M, Rülicke T, Izsvák Z. Germline transgenesis in rodents by pronuclear microinjection of Sleeping Beauty transposons. Nature Protocols. 9: 773-93. PMID 24625778 DOI: 10.1038/Nprot.2014.008 |
0.355 |
|
| 2014 |
Beyer AM, Raffai G, Weinberg BD, Fredrich K, Rodgers MS, Geurts AM, Jacob HJ, Dwinell MR, Lombard JH. Amelioration of salt-induced vascular dysfunction in mesenteric arteries of Dahl salt-sensitive rats by missense mutation of extracellular superoxide dismutase. American Journal of Physiology. Heart and Circulatory Physiology. 306: H339-47. PMID 24322611 DOI: 10.1152/Ajpheart.00619.2012 |
0.36 |
|
| 2014 |
Chen YG, Forsberg MH, Khaja S, Ciecko AE, Hessner MJ, Geurts AM. Gene targeting in NOD mouse embryos using zinc-finger nucleases. Diabetes. 63: 68-74. PMID 23974926 DOI: 10.2337/Db13-0192 |
0.304 |
|
| 2014 |
Parker CC, Chen H, Flagel SB, Geurts AM, Richards JB, Robinson TE, Solberg Woods LC, Palmer AA. Rats are the smart choice: Rationale for a renewed focus on rats in behavioral genetics. Neuropharmacology. 76: 250-8. PMID 23791960 DOI: 10.1016/J.Neuropharm.2013.05.047 |
0.378 |
|
| 2013 |
Flister MJ, Tsaih SW, O'Meara CC, Endres B, Hoffman MJ, Geurts AM, Dwinell MR, Lazar J, Jacob HJ, Moreno C. Identifying multiple causative genes at a single GWAS locus. Genome Research. 23: 1996-2002. PMID 24006081 DOI: 10.1101/Gr.160283.113 |
0.392 |
|
| 2013 |
Yang S, Takizawa A, Foeckler J, Zappa A, Gjoka M, Schilling R, Hansen C, Xu H, Kalloway S, Grzybowski M, Davis GD, Jacob HJ, Geurts AM. Derivation and genetic modification of embryonic stem cells from disease-model inbred rat strains. Stem Cells and Development. PMID 23635087 DOI: 10.1089/Scd.2012.0416 |
0.424 |
|
| 2013 |
Mattson DL, Lund H, Guo C, Rudemiller N, Geurts AM, Jacob H. Genetic mutation of recombination activating gene 1 in Dahl salt-sensitive rats attenuates hypertension and renal damage. American Journal of Physiology. Regulatory, Integrative and Comparative Physiology. 304: R407-14. PMID 23364523 DOI: 10.1152/Ajpregu.00304.2012 |
0.388 |
|
| 2013 |
Rangel-Filho A, Lazar J, Moreno C, Geurts A, Jacob HJ. Rab38 modulates proteinuria in model of hypertension-associated renal disease. Journal of the American Society of Nephrology : Jasn. 24: 283-92. PMID 23291471 DOI: 10.1681/Asn.2012090927 |
0.434 |
|
| 2013 |
Chen CC, Geurts AM, Jacob HJ, Fan F, Roman RJ. Heterozygous knockout of transforming growth factor-β1 protects Dahl S rats against high salt-induced renal injury. Physiological Genomics. 45: 110-8. PMID 23249995 DOI: 10.1152/Physiolgenomics.00119.2012 |
0.308 |
|
| 2013 |
Katter K, Geurts AM, Hoffmann O, Mátés L, Landa V, Hiripi L, Moreno C, Lazar J, Bashir S, Zidek V, Popova E, Jerchow B, Becker K, Devaraj A, Walter I, et al. Transposon-mediated transgenesis, transgenic rescue, and tissue-specific gene expression in rodents and rabbits. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 27: 930-41. PMID 23195032 DOI: 10.1096/Fj.12-205526 |
0.433 |
|
| 2013 |
Sorokin A, Miller B, Geurts AM, Imig JD. ET-1-induced contraction of renal afferent arterioles of Dahl salt-sensitive rats is impaired by targeted modification of a p66 Shc regulatory phosphorylation site Life Sciences. 93: e15. DOI: 10.1016/J.Lfs.2013.12.071 |
0.331 |
|
| 2012 |
Maroteaux G, Loos M, van der Sluis S, Koopmans B, Aarts E, van Gassen K, Geurts A, Largaespada DA, Spruijt BM, Stiedl O, Smit AB, Verhage M. High-throughput phenotyping of avoidance learning in mice discriminates different genotypes and identifies a novel gene. Genes, Brain, and Behavior. 11: 772-84. PMID 22846151 DOI: 10.1111/J.1601-183X.2012.00820.X |
0.503 |
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| 2012 |
Feng D, Yang C, Geurts AM, Kurth T, Liang M, Lazar J, Mattson DL, O'Connor PM, Cowley AW. Increased expression of NAD(P)H oxidase subunit p67(phox) in the renal medulla contributes to excess oxidative stress and salt-sensitive hypertension. Cell Metabolism. 15: 201-8. PMID 22326221 DOI: 10.1016/J.Cmet.2012.01.003 |
0.342 |
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| 2011 |
Wilber A, Ulloa Montoya F, Hammer L, Moriarity BS, Geurts AM, Largaespada DA, Verfaillie CM, McIvor RS, Lakshmipathy U. Efficient non-viral integration and stable gene expression in multipotent adult progenitor cells. Stem Cells International. 2011: 717069. PMID 21977042 DOI: 10.4061/2011/717069 |
0.679 |
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| 2011 |
Dwinell MR, Lazar J, Geurts AM. The emerging role for rat models in gene discovery. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 22: 466-75. PMID 21732192 DOI: 10.1007/S00335-011-9346-2 |
0.393 |
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| 2011 |
Xu D, Guo H, Xu X, Lu Z, Fassett J, Hu X, Xu Y, Tang Q, Hu D, Somani A, Geurts AM, Ostertag E, Bache RJ, Weir EK, Chen Y. Exacerbated pulmonary arterial hypertension and right ventricular hypertrophy in animals with loss of function of extracellular superoxide dismutase. Hypertension. 58: 303-9. PMID 21730301 DOI: 10.1161/Hypertensionaha.110.166819 |
0.343 |
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| 2011 |
Moreno C, Hoffman M, Stodola TJ, Didier DN, Lazar J, Geurts AM, North PE, Jacob HJ, Greene AS. Creation and characterization of a renin knockout rat. Hypertension. 57: 614-9. PMID 21242461 DOI: 10.1161/Hypertensionaha.110.163840 |
0.408 |
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| 2011 |
Taylor SB, Taylor AR, Markham JA, Geurts AM, Kanaskie BZ, Koenig JI. Disruption of the neuregulin 1 gene in the rat alters HPA axis activity and behavioral responses to environmental stimuli. Physiology & Behavior. 104: 205-14. PMID 21092742 DOI: 10.1016/J.Physbeh.2010.11.015 |
0.35 |
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| 2011 |
Carlson DF, Geurts AM, Garbe JR, Park CW, Rangel-Filho A, O'Grady SM, Jacob HJ, Steer CJ, Largaespada DA, Fahrenkrug SC. Efficient mammalian germline transgenesis by cis-enhanced Sleeping Beauty transposition. Transgenic Research. 20: 29-45. PMID 20352328 DOI: 10.1007/S11248-010-9386-5 |
0.529 |
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| 2010 |
Jacob HJ, Lazar J, Dwinell MR, Moreno C, Geurts AM. Gene targeting in the rat: advances and opportunities. Trends in Genetics : Tig. 26: 510-8. PMID 20869786 DOI: 10.1016/J.Tig.2010.08.006 |
0.407 |
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| 2010 |
Geurts AM, Moreno C. Zinc-finger nucleases: new strategies to target the rat genome. Clinical Science (London, England : 1979). 119: 303-11. PMID 20615201 DOI: 10.1042/Cs20100201 |
0.395 |
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| 2010 |
Geurts AM, Cost GJ, Rémy S, Cui X, Tesson L, Usal C, Ménoret S, Jacob HJ, Anegon I, Buelow R. Generation of gene-specific mutated rats using zinc-finger nucleases. Methods in Molecular Biology (Clifton, N.J.). 597: 211-25. PMID 20013236 DOI: 10.1007/978-1-60327-389-3_15 |
0.416 |
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| 2009 |
Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, Jenkins SS, Wood A, Cui X, Meng X, Vincent A, Lam S, Michalkiewicz M, Schilling R, Foeckler J, et al. Knockout rats via embryo microinjection of zinc-finger nucleases. Science (New York, N.Y.). 325: 433. PMID 19628861 DOI: 10.1126/Science.1172447 |
0.42 |
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| 2008 |
Aitman TJ, Critser JK, Cuppen E, Dominiczak A, Fernandez-Suarez XM, Flint J, Gauguier D, Geurts AM, Gould M, Harris PC, Holmdahl R, Hubner N, Izsvák Z, Jacob HJ, Kuramoto T, et al. Progress and prospects in rat genetics: a community view. Nature Genetics. 40: 516-22. PMID 18443588 DOI: 10.1038/Ng.147 |
0.408 |
|
| 2007 |
Hackett CS, Geurts AM, Hackett PB. Predicting preferential DNA vector insertion sites: implications for functional genomics and gene therapy. Genome Biology. 8: S12. PMID 18047689 DOI: 10.1186/Gb-2007-8-S1-S12 |
0.356 |
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| 2007 |
Lu B, Geurts AM, Poirier C, Petit DC, Harrison W, Overbeek PA, Bishop CE. Generation of rat mutants using a coat color-tagged Sleeping Beauty transposon system. Mammalian Genome : Official Journal of the International Mammalian Genome Society. 18: 338-46. PMID 17557177 DOI: 10.1007/S00335-007-9025-5 |
0.396 |
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| 2007 |
Michalkiewicz M, Michalkiewicz T, Geurts AM, Roman RJ, Slocum GR, Singer O, Weihrauch D, Greene AS, Kaldunski M, Verma IM, Jacob HJ, Cowley AW. Efficient transgenic rat production by a lentiviral vector. American Journal of Physiology. Heart and Circulatory Physiology. 293: H881-94. PMID 17322424 DOI: 10.1152/Ajpheart.00060.2007 |
0.411 |
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| 2006 |
Balciunas D, Wangensteen KJ, Wilber A, Bell J, Geurts A, Sivasubbu S, Wang X, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. Harnessing a high cargo-capacity transposon for genetic applications in vertebrates. Plos Genetics. 2: e169. PMID 17096595 DOI: 10.1371/Journal.Pgen.0020169 |
0.548 |
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| 2006 |
Geurts AM, Collier LS, Geurts JL, Oseth LL, Bell ML, Mu D, Lucito R, Godbout SA, Green LE, Lowe SW, Hirsch BA, Leinwand LA, Largaespada DA. Gene mutations and genomic rearrangements in the mouse as a result of transposon mobilization from chromosomal concatemers. Plos Genetics. 2: e156. PMID 17009875 DOI: 10.1371/Journal.Pgen.0020156 |
0.534 |
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| 2006 |
Geurts AM, Wilber A, Carlson CM, Lobitz PD, Clark KJ, Hackett PB, McIvor RS, Largaespada DA. Conditional gene expression in the mouse using a Sleeping Beauty gene-trap transposon. Bmc Biotechnology. 6: 30. PMID 16800892 DOI: 10.1186/1472-6750-6-30 |
0.536 |
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| 2006 |
Geurts AM, Hackett CS, Bell JB, Bergemann TL, Collier LS, Carlson CM, Largaespada DA, Hackett PB. Structure-based prediction of insertion-site preferences of transposons into chromosomes. Nucleic Acids Research. 34: 2803-11. PMID 16717285 DOI: 10.1093/Nar/Gkl301 |
0.538 |
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| 2006 |
Geurts AM, Hackett CS, Bell JB, Bergemann TL, Collier LS, Carlson CM, Largaespada DA, Hackett PB. 520. ProTIS, a Method for Prediction of Insertion-Site Preferences into Chromosomes of Vectors Used for Gene Therapy Molecular Therapy. 13: S200. DOI: 10.1016/J.Ymthe.2006.08.591 |
0.527 |
|
| 2006 |
Balciunas D, Wilber A, Wangensteen K, Bell J, Geurts A, Hackett PB, Largaespada DA, McIvor RS, Ekker SC. 385. Tol2 Transposon as a Gene Therapy Vector: Characterization, Optimization and Correction of Hereditary Tyrosinemia Type 1 in Mouse Molecular Therapy. 13: S147. DOI: 10.1016/J.Ymthe.2006.08.446 |
0.525 |
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| 2005 |
Liu G, Geurts AM, Yae K, Srinivasan AR, Fahrenkrug SC, Largaespada DA, Takeda J, Horie K, Olson WK, Hackett PB. Target-site preferences of Sleeping Beauty transposons. Journal of Molecular Biology. 346: 161-73. PMID 15663935 DOI: 10.1016/J.Jmb.2004.09.086 |
0.526 |
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| 2005 |
Wilber A, Montoya F, Geurts AM, Largaespada DA, Lakshmipathy U, McIvor RS. 193. Direct Comparison of Integration Efficiency and Stable Gene Expression Mediated by the Sleeping Beauty Transposon System and by the PhiC31 Phage Integrase System in Cultured Human Fibroblasts and in Various Stem Cell Targets Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.196 |
0.57 |
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| 2005 |
Bell JB, Hackett CS, Geurts AM, Carlson CM, Collier LS, Liu G, Largaespada DA, Hackett PB. 176. Target-Site Preferences of Sleeping Beauty Transposons in an Intron of the B-raf Oncogene Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.06.179 |
0.521 |
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| 2004 |
Clark KJ, Geurts AM, Bell JB, Hackett PB. Transposon vectors for gene-trap insertional mutagenesis in vertebrates. Genesis (New York, N.Y. : 2000). 39: 225-33. PMID 15286994 DOI: 10.1002/Gene.20049 |
0.353 |
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| 2003 |
Geurts AM, Yang Y, Clark KJ, Liu G, Cui Z, Dupuy AJ, Bell JB, Largaespada DA, Hackett PB. Gene transfer into genomes of human cells by the sleeping beauty transposon system. Molecular Therapy : the Journal of the American Society of Gene Therapy. 8: 108-17. PMID 12842434 DOI: 10.1016/S1525-0016(03)00099-6 |
0.547 |
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| 2002 |
Cui Z, Geurts AM, Liu G, Kaufman CD, Hackett PB. Structure-function analysis of the inverted terminal repeats of the sleeping beauty transposon. Journal of Molecular Biology. 318: 1221-35. PMID 12083513 DOI: 10.1016/S0022-2836(02)00237-1 |
0.31 |
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