| Year |
Citation |
Score |
| 2023 |
Al-Rahahleh RQ, Saville KM, Andrews JF, Wu Z, Koczor CA, Sobol RW. Overexpression of the WWE domain of RNF146 modulates poly-(ADP)-ribose dynamics at sites of DNA damage. Biorxiv : the Preprint Server For Biology. PMID 38234836 DOI: 10.1101/2023.12.29.573650 |
0.403 |
|
| 2023 |
Almohdar D, Gulkis M, Ortiz A, Tang Q, Sobol RW, Çağlayan M. Impact of polβ/XRCC1 interaction variants on the efficiency of nick sealing by DNA ligase IIIα in the base excision repair pathway. Journal of Molecular Biology. 168410. PMID 38135179 DOI: 10.1016/j.jmb.2023.168410 |
0.426 |
|
| 2023 |
Sobol RW. Editorial: DNA repair and nucleic acid therapeutics in cancer. Nar Cancer. 5: zcad044. PMID 37645072 DOI: 10.1093/narcan/zcad044 |
0.402 |
|
| 2023 |
Kratz A, Kim M, Kelly MR, Zheng F, Koczor CA, Li J, Ono K, Qin Y, Churas C, Chen J, Pillich RT, Park J, Modak M, Collier R, Licon K, ... ... Sobol RW, et al. A multi-scale map of protein assemblies in the DNA damage response. Cell Systems. PMID 37220749 DOI: 10.1016/j.cels.2023.04.007 |
0.365 |
|
| 2023 |
Koczor CA, Thompson MK, Sharma N, Prakash A, Sobol RW. Polβ/XRCC1 heterodimerization dictates DNA damage recognition and basal Polβ protein levels without interfering with mouse viability or fertility. Dna Repair. 123: 103452. PMID 36702010 DOI: 10.1016/j.dnarep.2023.103452 |
0.397 |
|
| 2022 |
Koczor CA, Saville KM, Al-Rahahleh RQ, Andrews JF, Li J, Sobol RW. Quantitative Analysis of Nuclear Poly(ADP-Ribose) Dynamics in Response to Laser-Induced DNA Damage. Methods in Molecular Biology (Clifton, N.J.). 2609: 43-59. PMID 36515828 DOI: 10.1007/978-1-0716-2891-1_3 |
0.494 |
|
| 2022 |
Li J, Beiser A, Dey NB, Takeda S, Saha LK, Hirota K, Parker LL, Carter M, Arrieta MI, Sobol RW. A high-throughput 384-well CometChip platform reveals a role for 3-methyladenine in the cellular response to etoposide-induced DNA damage. Nar Genomics and Bioinformatics. 4: lqac065. PMID 36110898 DOI: 10.1093/nargab/lqac065 |
0.495 |
|
| 2022 |
Li J, Koczor CA, Saville KM, Hayat F, Beiser A, McClellan S, Migaud ME, Sobol RW. Overcoming Temozolomide Resistance in Glioblastoma via Enhanced NAD Bioavailability and Inhibition of Poly-ADP-Ribose Glycohydrolase. Cancers. 14. PMID 35892832 DOI: 10.3390/cancers14153572 |
0.451 |
|
| 2022 |
Mancuso P, Tricarico R, Bhattacharjee V, Cosentino L, Kadariya Y, Jelinek J, Nicolas E, Einarson M, Beeharry N, Devarajan K, Katz RA, Dorjsuren DG, Sun H, Simeonov A, Giordano A, ... ... Sobol RW, et al. Correction to: Thymine DNA glycosylase as a novel target for melanoma. Oncogene. PMID 35505094 DOI: 10.1038/s41388-022-02335-5 |
0.412 |
|
| 2022 |
Fujii S, Sobol RW, Fuchs RP. Double-strand breaks: When DNA repair events accidentally meet. Dna Repair. 112: 103303. PMID 35219626 DOI: 10.1016/j.dnarep.2022.103303 |
0.495 |
|
| 2021 |
Li J, M Saville K, Ibrahim M, Zeng X, McClellan S, Angajala A, Beiser A, Andrews JF, Sun M, Koczor CA, Clark J, Hayat F, Makarov MV, Wilk A, Yates NA, ... ... Sobol RW, et al. NAD bioavailability mediates PARG inhibition-induced replication arrest, intra S-phase checkpoint and apoptosis in glioma stem cells. Nar Cancer. 3: zcab044. PMID 34806016 DOI: 10.1093/narcan/zcab044 |
0.408 |
|
| 2021 |
Koczor CA, Saville KM, Andrews JF, Clark J, Fang Q, Li J, Al-Rahahleh RQ, Ibrahim M, McClellan S, Makarov MV, Migaud ME, Sobol RW. Temporal dynamics of base excision/single-strand break repair protein complex assembly/disassembly are modulated by the PARP/NAD/SIRT6 axis. Cell Reports. 37: 109917. PMID 34731617 DOI: 10.1016/j.celrep.2021.109917 |
0.474 |
|
| 2021 |
Ge J, Ngo LP, Kaushal S, Tay IJ, Thadhani E, Kay JE, Mazzucato P, Chow DN, Fessler JL, Weingeist DM, Sobol RW, Samson LD, Floyd SR, Engelward BP. CometChip enables parallel analysis of multiple DNA repair activities. Dna Repair. 106: 103176. PMID 34365116 DOI: 10.1016/j.dnarep.2021.103176 |
0.557 |
|
| 2021 |
Thompson MK, Sobol RW, Prakash A. Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair. Biology. 10. PMID 34198612 DOI: 10.3390/biology10060530 |
0.358 |
|
| 2020 |
Saville KM, Clark J, Wilk A, Rogers GD, Andrews JF, Koczor CA, Sobol RW. NAD-mediated regulation of mammalian base excision repair. Dna Repair. 93: 102930. PMID 33087267 DOI: 10.1016/j.dnarep.2020.102930 |
0.506 |
|
| 2020 |
Hoang SM, Kaminski N, Bhargava R, Barroso-González J, Lynskey ML, García-Expósito L, Roncaioli JL, Wondisford AR, Wallace CT, Watkins SC, James DI, Waddell ID, Ogilvie D, Smith KM, da Veiga Leprevost F, ... ... Sobol RW, et al. Regulation of ALT-associated homology-directed repair by polyADP-ribosylation. Nature Structural & Molecular Biology. PMID 33046907 DOI: 10.1038/s41594-020-0512-7 |
0.49 |
|
| 2020 |
Wilk A, Hayat F, Cunningham R, Li J, Garavaglia S, Zamani L, Ferraris DM, Sykora P, Andrews J, Clark J, Davis A, Chaloin L, Rizzi M, Migaud M, Sobol RW. Extracellular NAD enhances PARP-dependent DNA repair capacity independently of CD73 activity. Scientific Reports. 10: 651. PMID 31959836 DOI: 10.1038/S41598-020-57506-9 |
0.562 |
|
| 2019 |
Sannai M, Doneddu V, Giri V, Seeholzer S, Nicolas E, Yip SC, Bassi MR, Mancuso P, Cortellino S, Cigliano A, Lurie R, Ding H, Chernoff J, Sobol RW, Yen TJ, et al. Modification of the base excision repair enzyme MBD4 by the small ubiquitin-like molecule SUMO1. Dna Repair. 82: 102687. PMID 31476572 DOI: 10.1016/J.Dnarep.2019.102687 |
0.588 |
|
| 2019 |
Fang Q, Andrews J, Sharma N, Wilk A, Clark J, Slyskova J, Koczor CA, Lans H, Prakash A, Sobol RW. Stability and sub-cellular localization of DNA polymerase β is regulated by interactions with NQO1 and XRCC1 in response to oxidative stress. Nucleic Acids Research. 47: 6269-6286. PMID 31287140 DOI: 10.1093/Nar/Gkz293 |
0.369 |
|
| 2019 |
Rai P, Sobol RW. Mechanisms of MTH1 inhibition-induced DNA strand breaks: The slippery slope from the oxidized nucleotide pool to genotoxic damage. Dna Repair. 77: 18-26. PMID 30852368 DOI: 10.1016/J.Dnarep.2019.03.001 |
0.525 |
|
| 2019 |
Mancuso P, Tricarico R, Bhattacharjee V, Cosentino L, Kadariya Y, Jelinek J, Nicolas E, Einarson M, Beeharry N, Devarajan K, Katz RA, Dorjsuren DG, Sun H, Simeonov A, Giordano A, ... ... Sobol RW, et al. Thymine DNA glycosylase as a novel target for melanoma. Oncogene. PMID 30674989 DOI: 10.1038/S41388-018-0640-2 |
0.53 |
|
| 2018 |
Li J, Svilar D, McClellan S, Kim JH, Ahn EE, Vens C, Wilson DM, Sobol RW. DNA Repair Molecular Beacon assay: a platform for real-time functional analysis of cellular DNA repair capacity. Oncotarget. 9: 31719-31743. PMID 30167090 DOI: 10.18632/Oncotarget.25859 |
0.838 |
|
| 2018 |
Sonavane M, Sykora P, Andrews JF, Sobol RW, Gassman NR. Camptothecin efficacy to poison Top1 is altered by Bisphenol A in mouse embryonic fibroblasts. Chemical Research in Toxicology. PMID 29799191 DOI: 10.1021/Acs.Chemrestox.8B00050 |
0.542 |
|
| 2018 |
Sykora P, Chiari Y, Heaton A, Moreno N, Glaberman S, Sobol RW. Application of the CometChip platform to assess DNA damage in field-collected blood samples from turtles. Environmental and Molecular Mutagenesis. PMID 29536573 DOI: 10.1002/Em.22183 |
0.587 |
|
| 2018 |
Sykora P, Witt KL, Revanna P, Smith-Roe SL, Dismukes J, Lloyd DG, Engelward BP, Sobol RW. Next generation high throughput DNA damage detection platform for genotoxic compound screening. Scientific Reports. 8: 2771. PMID 29426857 DOI: 10.1038/S41598-018-20995-W |
0.521 |
|
| 2018 |
Tricarico R, Mancuso P, Bhattacharjee V, Cosentino L, Nicolas E, Einarson M, Beeharry N, Devarajan K, Katz R, Dorjsuren DG, Simeonov A, Kadariya Y, Davidson G, Testa JR, Davidson I, ... ... Sobol RW, et al. Abstract 1940: Thymine DNA glycosylase (TDG) as a novel target for melanoma Cancer Research. 78: 1940-1940. DOI: 10.1158/1538-7445.Am2018-1940 |
0.528 |
|
| 2017 |
Simonelli V, Leuzzi G, Basile G, D'Errico M, Fortini P, Franchitto A, Viti V, Brown AR, Parlanti E, Pascucci B, Palli D, Giuliani A, Palombo F, Sobol RW, Dogliotti E. Crosstalk between mismatch repair and base excision repair in human gastric cancer. Oncotarget. 8: 84827-84840. PMID 29156686 DOI: 10.18632/Oncotarget.10185 |
0.531 |
|
| 2017 |
Golato T, Brenerman B, McNeill DR, Li J, Sobol RW, Wilson DM. Development of a Cell-Based Assay for Measuring Base Excision Repair Responses. Scientific Reports. 7: 13007. PMID 29021553 DOI: 10.1038/S41598-017-12963-7 |
0.555 |
|
| 2017 |
Sykora P, Kanno S, Akbari M, Kulikowicz T, Baptiste BA, Leandro GS, Lu H, Tian J, May A, Becker KA, Croteau DL, Wilson DM, Sobol RW, Yasui A, Bohr VA. DNA polymerase beta participates in mitochondrial DNA repair. Molecular and Cellular Biology. PMID 28559431 DOI: 10.1128/Mcb.00237-17 |
0.461 |
|
| 2017 |
Nagel ZD, Engelward BP, Brenner DJ, Begley TJ, Sobol RW, Bielas JH, Stambrook PJ, Wei Q, Hu JJ, Terry MB, Dilworth C, McAllister KA, Reinlib L, Worth L, Shaughnessy DT. Towards precision prevention: Technologies for identifying healthy individuals with high risk of disease. Mutation Research. 800: 14-28. PMID 28458064 DOI: 10.1016/J.Mrfmmm.2017.03.007 |
0.397 |
|
| 2017 |
Sawant A, Floyd AM, Dangeti M, Lei W, Sobol RW, Patrick SM. Differential role of base excision repair proteins in mediating cisplatin cytotoxicity. Dna Repair. PMID 28110804 DOI: 10.1016/J.Dnarep.2017.01.002 |
0.619 |
|
| 2016 |
Braganza A, Li J, Zeng X, Yates NA, Dey NB, Andrews J, Clark J, Zamani L, Wang XH, St Croix C, O'Sullivan R, Garcia-Exposito L, Brodsky JL, Sobol RW. UBE3B is a Calmodulin-Regulated, Mitochondria-Associated E3 Ubiquitin Ligase. The Journal of Biological Chemistry. PMID 28003368 DOI: 10.1074/Jbc.M116.766824 |
0.322 |
|
| 2016 |
Bigarella CL, Li J, Rimmelé P, Liang R, Sobol RW, Ghaffari S. FOXO3 is Essential for Protecting Hematopoietic Stem and Progenitor Cells from Oxidative DNA Damage. The Journal of Biological Chemistry. PMID 27994057 DOI: 10.1074/Jbc.M116.769455 |
0.593 |
|
| 2016 |
Fouquerel E, Lormand J, Bose A, Lee HT, Kim GS, Li J, Sobol RW, Freudenthal BD, Myong S, Opresko PL. Oxidative guanine base damage regulates human telomerase activity. Nature Structural & Molecular Biology. PMID 27820808 DOI: 10.1038/Nsmb.3319 |
0.464 |
|
| 2016 |
Soll JM, Sobol RW, Mosammaparast N. Regulation of DNA Alkylation Damage Repair: Lessons and Therapeutic Opportunities. Trends in Biochemical Sciences. PMID 27816326 DOI: 10.1016/J.Tibs.2016.10.001 |
0.512 |
|
| 2016 |
Srivas R, Shen JP, Yang CC, Sun SM, Li J, Gross AM, Jensen J, Licon K, Bojorquez-Gomez A, Klepper K, Huang J, Pekin D, Xu JL, Yeerna H, Sivaganesh V, ... ... Sobol RW, et al. A Network of Conserved Synthetic Lethal Interactions for Exploration of Precision Cancer Therapy. Molecular Cell. PMID 27453043 DOI: 10.1016/J.Molcel.2016.06.022 |
0.303 |
|
| 2016 |
Simonelli V, Leuzzi G, Basile G, D'Errico M, Fortini P, Franchitto A, Viti V, Brown AR, Parlanti E, Pascucci B, Palli D, Giuliani A, Palombo F, Sobol RW, Dogliotti E. Crosstalk between mismatch repair and base excision repair in human gastric cancer. Oncotarget. PMID 27340774 DOI: 10.18632/oncotarget.10185 |
0.44 |
|
| 2016 |
Godin SK, Zhang Z, Herken BW, Westmoreland JW, Lee AG, Mihalevic MJ, Yu Z, Sobol RW, Resnick MA, Bernstein KA. The Shu complex promotes error-free tolerance of alkylation-induced base excision repair products. Nucleic Acids Research. PMID 27298254 DOI: 10.1093/Nar/Gkw535 |
0.521 |
|
| 2016 |
Shen JP, Srivas R, Yang CC, Sun SM, Li JF, Gross A, Jensen J, Licon K, Bojoquez-Gomez A, Klepper K, Attikum Hv, Aza-Blanc P, Sobol R, Ideker T. Abstract NG02: A network of deeply conserved synthetic-lethal interactions for exploration of precision cancer therapy Cancer Research. 76. DOI: 10.1158/1538-7445.Am2016-Ng02 |
0.355 |
|
| 2016 |
Wilk AM, Fouquerel E, Johnston B, Trammell SAJ, Schambeau L, Andrews JF, Pannell L, Cooper SJ, Brenner C, Sobol RW. Abstract 4: Hyper activation of poly(ADP-ribose) polymerase 1 initiates large-scale metabolic changes in a cellular model of glioblastoma Cancer Research. 76: 4-4. DOI: 10.1158/1538-7445.Am2016-4 |
0.564 |
|
| 2016 |
Sykora P, Woodgate S, George J, Sobol RW. Abstract 3600: Next generation high capacity DNA damage detection assay for chemotherapy and genotoxic compound screening Cancer Research. 76: 3600-3600. DOI: 10.1158/1538-7445.Am2016-3600 |
0.455 |
|
| 2015 |
Sawant A, Kothandapani A, Zhitkovich A, Sobol RW, Patrick SM. Role of mismatch repair proteins in the processing of cisplatin interstrand cross-links. Dna Repair. 35: 126-136. PMID 26519826 DOI: 10.1016/J.Dnarep.2015.10.003 |
0.539 |
|
| 2015 |
Shen JP, Srivas R, Gross A, Li J, Jaehnig EJ, Sun SM, Bojorquez-Gomez A, Licon K, Sivaganesh V, Xu JL, Klepper K, Yeerna H, Pekin D, Qiu CP, van Attikum H, ... Sobol RW, et al. Chemogenetic profiling identifies RAD17 as synthetically lethal with checkpoint kinase inhibition. Oncotarget. PMID 26437225 DOI: 10.18632/Oncotarget.5928 |
0.401 |
|
| 2015 |
Chandran UR, Luthra S, Santana-Santos L, Mao P, Kim SH, Minata M, Li J, Benos PV, DeWang M, Hu B, Cheng SY, Nakano I, Sobol RW. Gene expression profiling distinguishes proneural glioma stem cells from mesenchymal glioma stem cells. Genomics Data. 5: 333-336. PMID 26251826 DOI: 10.1016/J.Gdata.2015.07.007 |
0.345 |
|
| 2015 |
Quiñones JL, Thapar U, Yu K, Fang Q, Sobol RW, Demple B. Enzyme mechanism-based, oxidative DNA-protein cross-links formed with DNA polymerase β in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 26124145 DOI: 10.1073/Pnas.1501101112 |
0.556 |
|
| 2015 |
Brown MF, Leibowitz BJ, Chen D, He K, Zou F, Sobol RW, Beer-Stolz D, Zhang L, Yu J. Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis. Cell Death & Disease. 6: e1729. PMID 25906152 DOI: 10.1038/Cddis.2015.104 |
0.464 |
|
| 2015 |
Wang J, Li J, Santana-Santos L, Shuda M, Sobol RW, Van Houten B, Qian W. A novel strategy for targeted killing of tumor cells: Induction of multipolar acentrosomal mitotic spindles with a quinazolinone derivative mdivi-1. Molecular Oncology. 9: 488-502. PMID 25458053 DOI: 10.1016/J.Molonc.2014.10.002 |
0.358 |
|
| 2015 |
Shen JP, Srivas R, Bojorquez-Gomez A, Licon K, Sivaganesh V, Xu JL, Yeerna H, Gross A, Li JF, Sobol R, Ideker T. Abstract 129: RAD17 loss of function is synthetically lethal with the checkpoint kinase inhibitors AZD7762 or MK-1775 Cancer Research. 75: 129-129. DOI: 10.1158/1538-7445.Am2015-129 |
0.472 |
|
| 2014 |
Fang Q, Inanc B, Schamus S, Wang XH, Wei L, Brown AR, Svilar D, Sugrue KF, Goellner EM, Zeng X, Yates NA, Lan L, Vens C, Sobol RW. HSP90 regulates DNA repair via the interaction between XRCC1 and DNA polymerase β. Nature Communications. 5: 5513. PMID 25423885 DOI: 10.1038/Ncomms6513 |
0.827 |
|
| 2014 |
Fouquerel E, Sobol RW. ARTD1 (PARP1) activation and NAD(+) in DNA repair and cell death. Dna Repair. 23: 27-32. PMID 25283336 DOI: 10.1016/J.Dnarep.2014.09.004 |
0.549 |
|
| 2014 |
Fouquerel E, Goellner EM, Yu Z, Gagné JP, Barbi de Moura M, Feinstein T, Wheeler D, Redpath P, Li J, Romero G, Migaud M, Van Houten B, Poirier GG, Sobol RW. ARTD1/PARP1 negatively regulates glycolysis by inhibiting hexokinase 1 independent of NAD+ depletion. Cell Reports. 8: 1819-31. PMID 25220464 DOI: 10.1016/J.Celrep.2014.08.036 |
0.82 |
|
| 2014 |
Shaughnessy DT, McAllister K, Worth L, Haugen AC, Meyer JN, Domann FE, Van Houten B, Mostoslavsky R, Bultman SJ, Baccarelli AA, Begley TJ, Sobol RW, Hirschey MD, Ideker T, Santos JH, et al. Mitochondria, energetics, epigenetics, and cellular responses to stress. Environmental Health Perspectives. 122: 1271-8. PMID 25127496 DOI: 10.1289/Ehp.1408418 |
0.415 |
|
| 2014 |
Agnihotri S, Burrell K, Buczkowicz P, Remke M, Golbourn B, Chornenkyy Y, Gajadhar A, Fernandez NA, Clarke ID, Barszczyk MS, Pajovic S, Ternamian C, Head R, Sabha N, Sobol RW, et al. ATM regulates 3-methylpurine-DNA glycosylase and promotes therapeutic resistance to alkylating agents. Cancer Discovery. 4: 1198-213. PMID 25100205 DOI: 10.1158/2159-8290.Cd-14-0157 |
0.498 |
|
| 2014 |
Bennett GR, Peters R, Wang XH, Hanne J, Sobol RW, Bundschuh R, Fishel R, Yoder KE. Repair of oxidative DNA base damage in the host genome influences the HIV integration site sequence preference. Plos One. 9: e103164. PMID 25051054 DOI: 10.1371/Journal.Pone.0103164 |
0.438 |
|
| 2014 |
Choi YJ, Li H, Son MY, Wang XH, Fornsaglio JL, Sobol RW, Lee M, Vijg J, Imholz S, Dollé ME, van Steeg H, Reiling E, Hasty P. Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair. Plos One. 9: e86358. PMID 24466051 DOI: 10.1371/Journal.Pone.0086358 |
0.543 |
|
| 2014 |
Lan L, Nakajima S, Wei L, Sun L, Hsieh CL, Sobol RW, Bruchez M, Van Houten B, Yasui A, Levine AS. Novel method for site-specific induction of oxidative DNA damage reveals differences in recruitment of repair proteins to heterochromatin and euchromatin. Nucleic Acids Research. 42: 2330-45. PMID 24293652 DOI: 10.1093/Nar/Gkt1233 |
0.614 |
|
| 2014 |
Srivas R, Shen JP, Li JF, Licon K, Wang ZZ, Bojoquez-Gomez A, Xu L, Gross A, Bean G, Sobol R, Ideker T. Abstract B34: High-throughput synthetic lethal interaction screening in model organisms as a strategy for the identification of novel therapeutic targets in cancer Molecular Cancer Research. 12. DOI: 10.1158/1557-3125.Modorg-B34 |
0.325 |
|
| 2014 |
Wang J, Qian W, Shuda M, Li J, Santana-Santos L, Sobol RW, Houten BV. Abstract 5085: Inducing multipolarity of acentrosomal mitotic spindles as a novel tumor-specific targeting strategy revealed by the antimitotic effect of mdivi-1 Cancer Research. 74: 5085-5085. DOI: 10.1158/1538-7445.Am2014-5085 |
0.359 |
|
| 2014 |
Woodgate SR, Whittaker C, George J, Sobol RW, Schamus-Haynes S, Engelward BP, Ge J. Abstract 2379: 96-Well CometChip validation for simultaneous treatment and measurement of DNA damage in a single platform Cancer Research. 74: 2379-2379. DOI: 10.1158/1538-7445.Am2014-2379 |
0.48 |
|
| 2013 |
Kothandapani A, Sawant A, Dangeti VS, Sobol RW, Patrick SM. Epistatic role of base excision repair and mismatch repair pathways in mediating cisplatin cytotoxicity. Nucleic Acids Research. 41: 7332-43. PMID 23761438 DOI: 10.1093/Nar/Gkt479 |
0.54 |
|
| 2013 |
Williams K, Sobol RW. Mutation research/fundamental and molecular mechanisms of mutagenesis: special issue: DNA repair and genetic instability. Mutation Research. 743: 1-3. PMID 23688353 DOI: 10.1016/J.Mrfmmm.2013.04.009 |
0.605 |
|
| 2013 |
Mao P, Joshi K, Li J, Kim SH, Li P, Santana-Santos L, Luthra S, Chandran UR, Benos PV, Smith L, Wang M, Hu B, Cheng SY, Sobol RW, Nakano I. Mesenchymal glioma stem cells are maintained by activated glycolytic metabolism involving aldehyde dehydrogenase 1A3. Proceedings of the National Academy of Sciences of the United States of America. 110: 8644-9. PMID 23650391 DOI: 10.1073/Pnas.1221478110 |
0.355 |
|
| 2013 |
Joshi K, Banasavadi-Siddegowda Y, Mo X, Kim SH, Mao P, Kig C, Nardini D, Sobol RW, Chow LM, Kornblum HI, Waclaw R, Beullens M, Nakano I. MELK-dependent FOXM1 phosphorylation is essential for proliferation of glioma stem cells. Stem Cells (Dayton, Ohio). 31: 1051-63. PMID 23404835 DOI: 10.1002/Stem.1358 |
0.362 |
|
| 2013 |
Li J, Braganza A, Sobol RW. Base excision repair facilitates a functional relationship between Guanine oxidation and histone demethylation. Antioxidants & Redox Signaling. 18: 2429-43. PMID 23311711 DOI: 10.1089/Ars.2012.5107 |
0.366 |
|
| 2013 |
Nagaria P, Svilar D, Brown AR, Wang XH, Sobol RW, Wyatt MD. SMUG1 but not UNG DNA glycosylase contributes to the cellular response to recovery from 5-fluorouracil induced replication stress. Mutation Research. 743: 26-32. PMID 23253900 DOI: 10.1016/J.Mrfmmm.2012.12.001 |
0.84 |
|
| 2013 |
Iyer P, Srinivasan A, Singh SK, Mascara GP, Zayitova S, Sidone B, Fouquerel E, Svilar D, Sobol RW, Bobola MS, Silber JR, Gold B. Synthesis and characterization of DNA minor groove binding alkylating agents. Chemical Research in Toxicology. 26: 156-68. PMID 23234400 DOI: 10.1021/Tx300437X |
0.8 |
|
| 2013 |
Shen JP, Srivas R, Bojorquez-Gomez A, Licon K, Li JF, Sobol RW, Ideker T. Cross-species synthetic lethal interaction screening as a strategy for the identification of novel therapeutic targets in cancer. Journal of Clinical Oncology. 31: 11105-11105. DOI: 10.1200/Jco.2013.31.15_Suppl.11105 |
0.343 |
|
| 2013 |
Mao P, Joshi K, Li Jf, Godlewski J, Mo Xk, Chen Sy, Sobol RW, Nakano I. Abstract 4904: Activation of aldehyde dehydrogenase is essential for growth of mesenchymal glioma stem cells. Cancer Research. 73: 4904-4904. DOI: 10.1158/1538-7445.Am2013-4904 |
0.35 |
|
| 2012 |
Li J, Luthra S, Wang XH, Chandran UR, Sobol RW. Transcriptional profiling reveals elevated Sox2 in DNA polymerase ß null mouse embryonic fibroblasts. American Journal of Cancer Research. 2: 699-713. PMID 23226616 DOI: 10.1158/1538-7445.Am2012-699 |
0.476 |
|
| 2012 |
Sobol RW. Genome instability caused by a germline mutation in the human DNA repair gene POLB. Plos Genetics. 8: e1003086. PMID 23144636 DOI: 10.1371/Journal.Pgen.1003086 |
0.606 |
|
| 2012 |
Svilar D, Dyavaiah M, Brown AR, Tang JB, Li J, McDonald PR, Shun TY, Braganza A, Wang XH, Maniar S, St Croix CM, Lazo JS, Pollack IF, Begley TJ, Sobol RW. Alkylation sensitivity screens reveal a conserved cross-species functionome. Molecular Cancer Research : McR. 10: 1580-96. PMID 23038810 DOI: 10.1158/1541-7786.Mcr-12-0168 |
0.815 |
|
| 2012 |
Svilar D, Vens C, Sobol RW. Quantitative, real-time analysis of base excision repair activity in cell lysates utilizing lesion-specific molecular beacons. Journal of Visualized Experiments : Jove. e4168. PMID 22895410 DOI: 10.3791/4168 |
0.798 |
|
| 2012 |
Srinivasan A, Wang L, Cline CJ, Xie Z, Sobol RW, Xie XQ, Gold B. Identification and characterization of human apurinic/apyrimidinic endonuclease-1 inhibitors. Biochemistry. 51: 6246-59. PMID 22788932 DOI: 10.1021/Bi300490R |
0.545 |
|
| 2012 |
Sobol RW. For MutY, it's all about the OG. Chemistry & Biology. 19: 313-4. PMID 22444586 DOI: 10.1016/J.Chembiol.2012.03.002 |
0.438 |
|
| 2012 |
Goellner EM, Svilar D, Almeida KH, Sobol RW. Targeting DNA polymerase ß for therapeutic intervention. Current Molecular Pharmacology. 5: 68-87. PMID 22122465 DOI: 10.2174/1874-470211205010068 |
0.817 |
|
| 2012 |
Rios-Perez JA, Beumer JH, Appleman LJ, Tawbi HA, Chu E, Stoller RG, Belani CP, Jiang Y, Sobol RW, Shepherd SP, Giranda VL, Chen AP, Huggins-Puhalla SL. ABT-888 (veliparib) in combination with weekly carboplatin and paclitaxel in advanced solid tumors. Journal of Clinical Oncology. 30: TPS1138-TPS1138. DOI: 10.1200/Jco.2012.30.15_Suppl.Tps1138 |
0.35 |
|
| 2012 |
Srinivasan A, Xie X, Sobol RW, Gold B. Abstract 4697: Identification, characterization and effects of inhibitors of the human Apurinic/Apyrimidinic Endonuclease 1 (APE1) protein Cancer Research. 72: 4697-4697. DOI: 10.1158/1538-7445.Am2012-4697 |
0.591 |
|
| 2012 |
Wyatt MD, Brady K, Litvinchuk A, Noxon V, Wang X, Sobol RW. Abstract 2549: Chromosomal instability and DNA repair status during folic acid deficiency in breast cancer cells Cancer Research. 72: 2549-2549. DOI: 10.1158/1538-7445.Am2012-2549 |
0.438 |
|
| 2011 |
Mutamba JT, Svilar D, Prasongtanakij S, Wang XH, Lin YC, Dedon PC, Sobol RW, Engelward BP. XRCC1 and base excision repair balance in response to nitric oxide. Dna Repair. 10: 1282-93. PMID 22041025 DOI: 10.1016/J.Dnarep.2011.10.008 |
0.837 |
|
| 2011 |
Yoder KE, Espeseth A, Wang XH, Fang Q, Russo MT, Lloyd RS, Hazuda D, Sobol RW, Fishel R. The base excision repair pathway is required for efficient lentivirus integration. Plos One. 6: e17862. PMID 21448280 DOI: 10.1371/Journal.Pone.0017862 |
0.378 |
|
| 2011 |
Li H, Wang P, Sun Q, Ding WX, Yin XM, Sobol RW, Stolz DB, Yu J, Zhang L. Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1. Cancer Research. 71: 3625-34. PMID 21444671 DOI: 10.1158/0008-5472.Can-10-4475 |
0.358 |
|
| 2011 |
Goellner EM, Grimme B, Brown AR, Lin YC, Wang XH, Sugrue KF, Mitchell L, Trivedi RN, Tang JB, Sobol RW. Overcoming temozolomide resistance in glioblastoma via dual inhibition of NAD+ biosynthesis and base excision repair. Cancer Research. 71: 2308-17. PMID 21406402 DOI: 10.1158/0008-5472.Can-10-3213 |
0.844 |
|
| 2011 |
Tang JB, Svilar D, Trivedi RN, Wang XH, Goellner EM, Moore B, Hamilton RL, Banze LA, Brown AR, Sobol RW. N-methylpurine DNA glycosylase and DNA polymerase beta modulate BER inhibitor potentiation of glioma cells to temozolomide. Neuro-Oncology. 13: 471-86. PMID 21377995 DOI: 10.1093/Neuonc/Nor011 |
0.823 |
|
| 2011 |
Kothandapani A, Dangeti VS, Brown AR, Banze LA, Wang XH, Sobol RW, Patrick SM. Novel role of base excision repair in mediating cisplatin cytotoxicity. The Journal of Biological Chemistry. 286: 14564-74. PMID 21357694 DOI: 10.1074/Jbc.M111.225375 |
0.634 |
|
| 2011 |
Svilar D, Goellner EM, Almeida KH, Sobol RW. Base excision repair and lesion-dependent subpathways for repair of oxidative DNA damage. Antioxidants & Redox Signaling. 14: 2491-507. PMID 20649466 DOI: 10.1089/Ars.2010.3466 |
0.822 |
|
| 2010 |
Pollack IF, Hamilton RL, Sobol RW, Nikiforova MN, Nikiforov YE, Lyons-Weiler MA, LaFramboise WA, Burger PC, Brat DJ, Rosenblum MK, Gilles FH, Yates AJ, Zhou T, Cohen KJ, Finlay JL, et al. Mismatch repair deficiency is an uncommon mechanism of alkylator resistance in pediatric malignant gliomas: a report from the Children's Oncology Group. Pediatric Blood & Cancer. 55: 1066-71. PMID 20589656 DOI: 10.1002/Pbc.22634 |
0.348 |
|
| 2010 |
Jelezcova E, Trivedi RN, Wang XH, Tang JB, Brown AR, Goellner EM, Schamus S, Fornsaglio JL, Sobol RW. Parp1 activation in mouse embryonic fibroblasts promotes Pol beta-dependent cellular hypersensitivity to alkylation damage. Mutation Research. 686: 57-67. PMID 20096707 DOI: 10.1016/J.Mrfmmm.2010.01.016 |
0.783 |
|
| 2010 |
Tang JB, Goellner EM, Wang XH, Trivedi RN, St Croix CM, Jelezcova E, Svilar D, Brown AR, Sobol RW. Bioenergetic metabolites regulate base excision repair-dependent cell death in response to DNA damage. Molecular Cancer Research : McR. 8: 67-79. PMID 20068071 DOI: 10.1158/1541-7786.Mcr-09-0411 |
0.829 |
|
| 2010 |
Asagoshi K, Liu Y, Masaoka A, Lan L, Prasad R, Horton JK, Brown AR, Wang XH, Bdour HM, Sobol RW, Taylor JS, Yasui A, Wilson SH. DNA polymerase beta-dependent long patch base excision repair in living cells. Dna Repair. 9: 109-19. PMID 20006562 DOI: 10.1016/J.Dnarep.2009.11.002 |
0.41 |
|
| 2009 |
Tawbi HA, Buch S, Pancoska P, Lin Y, Saul M, Romkes M, Sobol R, Kirkwood JM. Prediction of response to alkylator-based chemotherapy in metastatic melanoma (MM) using gene expression and promoter methylation signatures. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 27: 9009. PMID 27962356 DOI: 10.1200/Jco.2009.27.15_Suppl.9009 |
0.301 |
|
| 2009 |
Jones LE, Ying L, Hofseth AB, Jelezcova E, Sobol RW, Ambs S, Harris CC, Espey MG, Hofseth LJ, Wyatt MD. Differential effects of reactive nitrogen species on DNA base excision repair initiated by the alkyladenine DNA glycosylase. Carcinogenesis. 30: 2123-9. PMID 19864471 DOI: 10.1093/Carcin/Bgp256 |
0.617 |
|
| 2009 |
Taioli E, Ragin C, Wang XH, Chen J, Langevin SM, Brown AR, Gollin SM, Garte S, Sobol RW. Recurrence in oral and pharyngeal cancer is associated with quantitative MGMT promoter methylation. Bmc Cancer. 9: 354. PMID 19807915 DOI: 10.1186/1471-2407-9-354 |
0.326 |
|
| 2009 |
Yoshizawa K, Jelezcova E, Brown AR, Foley JF, Nyska A, Cui X, Hofseth LJ, Maronpot RM, Wilson SH, Sepulveda AR, Sobol RW. Gastrointestinal hyperplasia with altered expression of DNA polymerase beta. Plos One. 4: e6493. PMID 19654874 DOI: 10.1371/Journal.Pone.0006493 |
0.377 |
|
| 2008 |
Allen D, Herbert DC, McMahan CA, Rotrekl V, Sobol RW, Wilson SH, Walter CA. Mutagenesis is elevated in male germ cells obtained from DNA polymerase-beta heterozygous mice. Biology of Reproduction. 79: 824-31. PMID 18650495 DOI: 10.1095/Biolreprod.108.069104 |
0.53 |
|
| 2008 |
Kronenberg G, Harms C, Sobol RW, Cardozo-Pelaez F, Linhart H, Winter B, Balkaya M, Gertz K, Gay SB, Cox D, Eckart S, Ahmadi M, Juckel G, Kempermann G, Hellweg R, et al. Folate deficiency induces neurodegeneration and brain dysfunction in mice lacking uracil DNA glycosylase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 7219-30. PMID 18614692 DOI: 10.1523/Jneurosci.0940-08.2008 |
0.352 |
|
| 2008 |
Trivedi RN, Wang XH, Jelezcova E, Goellner EM, Tang JB, Sobol RW. Human methyl purine DNA glycosylase and DNA polymerase beta expression collectively predict sensitivity to temozolomide. Molecular Pharmacology. 74: 505-16. PMID 18477668 DOI: 10.1124/Mol.108.045112 |
0.826 |
|
| 2008 |
Sobol RW. CHIPping away at base excision repair. Molecular Cell. 29: 413-5. PMID 18313379 DOI: 10.1016/J.Molcel.2008.02.004 |
0.47 |
|
| 2007 |
Almeida KH, Sobol RW. A unified view of base excision repair: lesion-dependent protein complexes regulated by post-translational modification. Dna Repair. 6: 695-711. PMID 17337257 DOI: 10.1016/J.Dnarep.2007.01.009 |
0.549 |
|
| 2007 |
Sobol RW. DNA polymerase beta null mouse embryonic fibroblasts harbor a homozygous null mutation in DNA polymerase iota. Dna Repair. 6: 3-7. PMID 16979388 DOI: 10.1016/J.Dnarep.2006.08.005 |
0.554 |
|
| 2006 |
Pollack IF, Hamilton RL, Sobol RW, Burnham J, Yates AJ, Holmes EJ, Zhou T, Finlay JL. O6-methylguanine-DNA methyltransferase expression strongly correlates with outcome in childhood malignant gliomas: results from the CCG-945 Cohort. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 24: 3431-7. PMID 16849758 DOI: 10.1200/Jco.2006.05.7265 |
0.349 |
|
| 2006 |
Sobol RW, Tawbi H, Jukic DM, Mule K, Mascari R, Kirkwood JM. Mismatch repair (MMR) and base excision repair (BER) protein expression correlates with clinical response to dacarbazine (DTIC)/temozolomide (TMZ) therapy of patients with metastatic melanoma Journal of Clinical Oncology. 24: 8015-8015. DOI: 10.1200/Jco.2006.24.18_Suppl.8015 |
0.477 |
|
| 2005 |
Trivedi RN, Almeida KH, Fornsaglio JL, Schamus S, Sobol RW. The role of base excision repair in the sensitivity and resistance to temozolomide-mediated cell death. Cancer Research. 65: 6394-400. PMID 16024643 DOI: 10.1158/0008-5472.Can-05-0715 |
0.616 |
|
| 2004 |
Endres M, Biniszkiewicz D, Sobol RW, Harms C, Ahmadi M, Lipski A, Katchanov J, Mergenthaler P, Dirnagl U, Wilson SH, Meisel A, Jaenisch R. Increased postischemic brain injury in mice deficient in uracil-DNA glycosylase. The Journal of Clinical Investigation. 113: 1711-21. PMID 15199406 DOI: 10.1172/Jci20926 |
0.436 |
|
| 2003 |
Cabelof DC, Guo Z, Raffoul JJ, Sobol RW, Wilson SH, Richardson A, Heydari AR. Base excision repair deficiency caused by polymerase beta haploinsufficiency: accelerated DNA damage and increased mutational response to carcinogens. Cancer Research. 63: 5799-807. PMID 14522902 |
0.425 |
|
| 2003 |
Sobol RW, Kartalou M, Almeida KH, Joyce DF, Engelward BP, Horton JK, Prasad R, Samson LD, Wilson SH. Base excision repair intermediates induce p53-independent cytotoxic and genotoxic responses. The Journal of Biological Chemistry. 278: 39951-9. PMID 12882965 DOI: 10.1074/Jbc.M306592200 |
0.611 |
|
| 2003 |
Sobol RW, Foley JF, Nyska A, Davidson MG, Wilson SH. Regulated over-expression of DNA polymerase beta mediates early onset cataract in mice. Dna Repair. 2: 609-22. PMID 12713817 DOI: 10.1016/S1568-7864(03)00026-0 |
0.416 |
|
| 2002 |
Horton JK, Baker A, Berg BJ, Sobol RW, Wilson SH. Involvement of DNA polymerase beta in protection against the cytotoxicity of oxidative DNA damage. Dna Repair. 1: 317-33. PMID 12509250 DOI: 10.1016/S1568-7864(02)00008-3 |
0.487 |
|
| 2002 |
Lavrik OI, Kolpashchikov DM, Prasad R, Sobol RW, Wilson SH. Binary system for selective photoaffinity labeling of base excision repair DNA polymerases. Nucleic Acids Research. 30: e73. PMID 12136121 DOI: 10.1093/Nar/Gnf073 |
0.563 |
|
| 2002 |
Sobol RW, Watson DE, Nakamura J, Yakes FM, Hou E, Horton JK, Ladapo J, Van Houten B, Swenberg JA, Tindall KR, Samson LD, Wilson SH. Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress. Proceedings of the National Academy of Sciences of the United States of America. 99: 6860-5. PMID 11983862 DOI: 10.1073/Pnas.092662499 |
0.513 |
|
| 2001 |
Tomicic MT, Thust R, Sobol RW, Kaina B. DNA polymerase β mediates protection of mammalian cells against ganciclovir-induced cytotoxicity and DNA breakage Cancer Research. 61: 7399-7403. PMID 11606369 |
0.4 |
|
| 2001 |
Sobol RW, Wilson SH. Mammalian DNA β-polymerase in base excision repair of alkylation damage Progress in Nucleic Acid Research and Molecular Biology. 68: 57-74. PMID 11554313 DOI: 10.1016/S0079-6603(01)68090-5 |
0.523 |
|
| 2001 |
Lavrik OI, Prasad R, Sobol RW, Horton JK, Ackerman EJ, Wilson SH. Photoaffinity labeling of mouse fibroblast enzymes by a base excision repair intermediate. Evidence for the role of poly(ADP-ribose) polymerase-1 in DNA repair. The Journal of Biological Chemistry. 276: 25541-8. PMID 11340072 DOI: 10.1074/Jbc.M102125200 |
0.556 |
|
| 2000 |
Wilson SH, Sobol RW, Beard WA, Horton JK, Prasad R, Vande Berg BJ. DNA polymerase beta and mammalian base excision repair. Cold Spring Harbor Symposia On Quantitative Biology. 65: 143-55. PMID 12760029 DOI: 10.1101/Sqb.2000.65.143 |
0.544 |
|
| 2000 |
Sobol RW, Prasad R, Evenski A, Baker A, Yang XP, Horton JK, Wilson SH. The lyase activity of the DNA repair protein beta-polymerase protects from DNA-damage-induced cytotoxicity. Nature. 405: 807-10. PMID 10866204 DOI: 10.1038/35015598 |
0.594 |
|
| 1999 |
Ochs K, Sobol RW, Wilson SH, Kaina B. Cells deficient in DNA polymerase β are hypersensitive to alkylating agentinduced apoptosis and chromosomal breakage Cancer Research. 59: 1544-1551. PMID 10197627 |
0.404 |
|
| 1998 |
Fortini P, Pascucci B, Parlanti E, Sobol RW, Wilson SH, Dogliotti E. Different DNA polymerases are involved in the short- and long-patch base excision repair in mammalian cells Biochemistry. 37: 3575-3580. PMID 9530283 DOI: 10.1021/Bi972999H |
0.506 |
|
| 1998 |
Chen KH, Yakes FM, Srivastava DK, Singhal RK, Sobol RW, Horton JK, Van Houten B, Wilson SH. Up-regulation of base excision repair correlates with enhanced protection against a DNA damaging agent in mouse cell lines. Nucleic Acids Research. 26: 2001-7. PMID 9518496 DOI: 10.1093/Nar/26.8.2001 |
0.627 |
|
| 1998 |
Biade S, Sobol RW, Wilson SH, Matsumoto Y. Impairment of proliferating cell nuclear antigen-dependent apurinic/apyrimidinic site repair on linear DNA Journal of Biological Chemistry. 273: 898-902. PMID 9422747 DOI: 10.1074/Jbc.273.2.898 |
0.575 |
|
| 1997 |
Fortini P, Pascucci B, Sobol R, Wilson S, Dogliotti E. P IV.6 Base excision repair in mammalian cells occurs also in the absence of DNA polymerase β Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 379: S29. DOI: 10.1016/S0027-5107(97)82690-5 |
0.524 |
|
| 1996 |
Sobol RW, Horton JK, Kühn R, Gu H, Singhal RK, Prasad R, Rajewsky K, Wilson SH. Requirement of mammalian DNA polymerase-beta in base-excision repair. Nature. 379: 183-6. PMID 8538772 DOI: 10.1038/379183A0 |
0.58 |
|
| 1996 |
Sobol RW, Norton JK, Kühn R, Gu H, Singhal RK, Prasad R, Rajewsky K, Wilson SH. Correction: Requirement of mammalian DNA polymerase-β in base-excision repair Nature. 383: 457-457. DOI: 10.1038/383457B0 |
0.377 |
|
| 1996 |
Sobol RW, Norton JK, Kühn R, Gu H, Singhal RK, Prasad R, Rajewsky K, Wilson SH. Requirement of mammalian DNA polymerase-β in base-excision repair Nature. 379: 848-848. DOI: 10.1038/379848b0 |
0.434 |
|
| 1993 |
Sobol RW, Fisher WL, Reichenbach NL, Kumar A, Beard WA, Wilson SH, Charubala R, Pfleiderer W, Suhadolnik RJ. HIV-1 reverse transcriptase: inhibition by 2',5'-oligoadenylates. Biochemistry. 32: 12112-8. PMID 7692966 DOI: 10.1021/Bi00096A023 |
0.321 |
|
| 1991 |
Sobol RW, Suhadolnik RJ, Kumar A, Lee BJ, Hatfield DL, Wilson SH. Localization of a polynucleotide binding region in the HIV-1 reverse transcriptase: Implications for primer binding Biochemistry. 30: 10623-10631. PMID 1718424 DOI: 10.1021/Bi00108A004 |
0.307 |
|
| 1991 |
Müller WE, Weiler BE, Charubala R, Pfleiderer W, Leserman L, Sobol RW, Suhadolnik RJ, Schröder HC. Cordycepin analogues of 2',5'-oligoadenylate inhibit human immunodeficiency virus infection via inhibition of reverse transcriptase. Biochemistry. 30: 2027-33. PMID 1705437 DOI: 10.1021/Bi00222A004 |
0.343 |
|
| 1990 |
Charachon G, Sobol RW, Bisbal C, Salehzada T, Silhol M, Charubala R, Pfleiderer W, Lebleu B, Suhadolnik RJ. Phosphorothioate analogues of (2'-5')(A)4: agonist and antagonist activities in intact cells. Biochemistry. 29: 2550-6. PMID 2159324 DOI: 10.1021/Bi00462A017 |
0.324 |
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