Year |
Citation |
Score |
2021 |
Kuppuswamy D, Chinnakkannu P, Reese C, Hoffman S. . The Journal of Pharmacology and Experimental Therapeutics. PMID 33879542 DOI: 10.1124/jpet.120.000424 |
0.351 |
|
2018 |
Chinnakkannu P, Reese C, Gaspar JA, Panneerselvam S, Pleasant-Jenkins D, Mukherjee R, Baicu C, Tourkina E, Hoffman S, Kuppuswamy D. Suppression of angiotensin II-induced pathological changes in heart and kidney by the caveolin-1 scaffolding domain peptide. Plos One. 13: e0207844. PMID 30576317 DOI: 10.1371/Journal.Pone.0207844 |
0.381 |
|
2017 |
Pleasant-Jenkins D, Reese C, Chinnakkannu P, Kasiganesan H, Tourkina E, Hoffman S, Kuppuswamy D. Reversal of maladaptive fibrosis and compromised ventricular function in the pressure overloaded heart by a caveolin-1 surrogate peptide. Laboratory Investigation; a Journal of Technical Methods and Pathology. PMID 28112757 DOI: 10.1038/Labinvest.2016.153 |
0.424 |
|
2015 |
Balasubramanian S, Pleasant DL, Kasiganesan H, Quinones L, Zhang Y, Sundararaj KP, Roche S, O'Connor R, Bradshaw AD, Kuppuswamy D. Dasatinib Attenuates Pressure Overload Induced Cardiac Fibrosis in a Murine Transverse Aortic Constriction Model. Plos One. 10: e0140273. PMID 26458186 DOI: 10.1371/Journal.Pone.0140273 |
0.554 |
|
2015 |
Sundararaj K, Pleasant DL, Moschella PC, Panneerselvam K, Balasubramanian S, Kuppuswamy D. mTOR Complexes Repress Hypertrophic Agonist-Stimulated Expression of Connective Tissue Growth Factor in Adult Cardiac Muscle Cells. Journal of Cardiovascular Pharmacology. PMID 26371948 DOI: 10.1097/Fjc.0000000000000322 |
0.766 |
|
2015 |
Palanisamy AP, Suryakumar G, Panneerselvam K, Willey CD, Kuppuswamy D. A Kinase-Independent Function of c-Src Mediates p130Cas Phosphorylation at the Serine-639 Site in Pressure Overloaded Myocardium. Journal of Cellular Biochemistry. 116: 2793-803. PMID 25976166 DOI: 10.1002/Jcb.25224 |
0.764 |
|
2014 |
Kendall RT, Lee MH, Pleasant DL, Robinson K, Kuppuswamy D, McDermott PJ, Luttrell LM. Arrestin-dependent angiotensin AT1 receptor signaling regulates Akt and mTor-mediated protein synthesis. The Journal of Biological Chemistry. 289: 26155-66. PMID 25081544 DOI: 10.1074/Jbc.M114.595728 |
0.534 |
|
2013 |
Moschella PC, McKillop J, Pleasant DL, Harston RK, Balasubramanian S, Kuppuswamy D. mTOR complex 2 mediates Akt phosphorylation that requires PKCε in adult cardiac muscle cells. Cellular Signalling. 25: 1904-12. PMID 23673367 DOI: 10.1016/J.Cellsig.2013.05.001 |
0.784 |
|
2012 |
Balasubramanian S, Quinones L, Kasiganesan H, Zhang Y, Pleasant DL, Sundararaj KP, Zile MR, Bradshaw AD, Kuppuswamy D. β3 integrin in cardiac fibroblast is critical for extracellular matrix accumulation during pressure overload hypertrophy in mouse. Plos One. 7: e45076. PMID 22984613 DOI: 10.1371/Journal.Pone.0045076 |
0.432 |
|
2012 |
Cheng G, Kasiganesan H, Baicu CF, Wallenborn JG, Kuppuswamy D, Cooper G. Cytoskeletal role in protection of the failing heart by β-adrenergic blockade. American Journal of Physiology. Heart and Circulatory Physiology. 302: H675-87. PMID 22081703 DOI: 10.1152/Ajpheart.00867.2011 |
0.454 |
|
2011 |
Harston RK, Kuppuswamy D. Integrins are the necessary links to hypertrophic growth in cardiomyocytes. Journal of Signal Transduction. 2011: 521742. PMID 21637377 DOI: 10.1155/2011/521742 |
0.416 |
|
2011 |
Harston RK, McKillop JC, Moschella PC, Van Laer A, Quinones LS, Baicu CF, Balasubramanian S, Zile MR, Kuppuswamy D. Rapamycin treatment augments both protein ubiquitination and Akt activation in pressure-overloaded rat myocardium. American Journal of Physiology. Heart and Circulatory Physiology. 300: H1696-706. PMID 21357504 DOI: 10.1152/Ajpheart.00545.2010 |
0.77 |
|
2010 |
Cheng G, Takahashi M, Shunmugavel A, Wallenborn JG, DePaoli-Roach AA, Gergs U, Neumann J, Kuppuswamy D, Menick DR, Cooper G. Basis for MAP4 dephosphorylation-related microtubule network densification in pressure overload cardiac hypertrophy. The Journal of Biological Chemistry. 285: 38125-40. PMID 20889984 DOI: 10.1074/Jbc.M110.148650 |
0.45 |
|
2010 |
Balasubramanian S, Mani SK, Kasiganesan H, Baicu CC, Kuppuswamy D. Hypertrophic stimulation increases beta-actin dynamics in adult feline cardiomyocytes. Plos One. 5: e11470. PMID 20635003 DOI: 10.1371/Journal.Pone.0011470 |
0.335 |
|
2010 |
Chinnakkannu P, Samanna V, Cheng G, Ablonczy Z, Baicu CF, Bethard JR, Menick DR, Kuppuswamy D, Cooper G. Site-specific microtubule-associated protein 4 dephosphorylation causes microtubule network densification in pressure overload cardiac hypertrophy. The Journal of Biological Chemistry. 285: 21837-48. PMID 20436166 DOI: 10.1074/Jbc.M110.120709 |
0.342 |
|
2010 |
Suryakumar G, Kasiganesan H, Balasubramanian S, Kuppuswamy D. Lack of beta3 integrin signaling contributes to calpain-mediated myocardial cell loss in pressure-overloaded myocardium. Journal of Cardiovascular Pharmacology. 55: 567-73. PMID 20224428 DOI: 10.1097/Fjc.0B013E3181D9F5D4 |
0.348 |
|
2009 |
Mani SK, Balasubramanian S, Zavadzkas JA, Jeffords LB, Rivers WT, Zile MR, Mukherjee R, Spinale FG, Kuppuswamy D. Calpain inhibition preserves myocardial structure and function following myocardial infarction. American Journal of Physiology. Heart and Circulatory Physiology. 297: H1744-51. PMID 19734364 DOI: 10.1152/Ajpheart.00338.2009 |
0.348 |
|
2009 |
Johnston RK, Balasubramanian S, Kasiganesan H, Baicu CF, Zile MR, Kuppuswamy D. Beta3 integrin-mediated ubiquitination activates survival signaling during myocardial hypertrophy. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 23: 2759-71. PMID 19364763 DOI: 10.1096/Fj.08-127480 |
0.45 |
|
2009 |
Balasubramanian S, Johnston RK, Moschella PC, Mani SK, Tuxworth WJ, Kuppuswamy D. mTOR in growth and protection of hypertrophying myocardium. Cardiovascular & Hematological Agents in Medicinal Chemistry. 7: 52-63. PMID 19149544 DOI: 10.2174/187152509787047603 |
0.759 |
|
2008 |
Willey CD, Palanisamy AP, Johnston RK, Mani SK, Shiraishi H, Tuxworth WJ, Zile MR, Balasubramanian S, Kuppuswamy D. STAT3 activation in pressure-overloaded feline myocardium: role for integrins and the tyrosine kinase BMX. International Journal of Biological Sciences. 4: 184-99. PMID 18612371 DOI: 10.7150/Ijbs.4.184 |
0.798 |
|
2008 |
Mani SK, Shiraishi H, Balasubramanian S, Yamane K, Chellaiah M, Cooper G, Banik N, Zile MR, Kuppuswamy D. In vivo administration of calpeptin attenuates calpain activation and cardiomyocyte loss in pressure-overloaded feline myocardium. American Journal of Physiology. Heart and Circulatory Physiology. 295: H314-26. PMID 18487434 DOI: 10.1152/Ajpheart.00085.2008 |
0.477 |
|
2008 |
Tuxworth WJ, Shiraishi H, Moschella PC, Yamane K, McDermott PJ, Kuppuswamy D. Translational activation of 5'-TOP mRNA in pressure overload myocardium. Basic Research in Cardiology. 103: 41-53. PMID 17955327 DOI: 10.1007/S00395-007-0682-Z |
0.743 |
|
2008 |
Johnston RK, Van Laer AO, Baicu CF, Zile MR, Kuppuswamy D. Rapamycin Augments Akt Activation in In Vitro and In Vivo Models of Cardiac Hypertrophy Journal of Cardiac Failure. 14: S44. DOI: 10.1016/J.Cardfail.2008.06.298 |
0.469 |
|
2007 |
Moschella PC, Rao VU, McDermott PJ, Kuppuswamy D. Regulation of mTOR and S6K1 activation by the nPKC isoforms, PKCepsilon and PKCdelta, in adult cardiac muscle cells. Journal of Molecular and Cellular Cardiology. 43: 754-66. PMID 17976640 DOI: 10.1016/J.Yjmcc.2007.09.015 |
0.761 |
|
2007 |
Chellaiah MA, Kuppuswamy D, Lasky L, Linder S. Phosphorylation of a Wiscott-Aldrich syndrome protein-associated signal complex is critical in osteoclast bone resorption. The Journal of Biological Chemistry. 282: 10104-16. PMID 17283076 DOI: 10.1074/Jbc.M608957200 |
0.536 |
|
2007 |
Mani SK, Shiraishi H, Balasubramanian S, Yamane K, Chellaiah M, Cai SX, Boggs JM, Cooper G, Zile MR, Kuppuswamy D. Cardiomyocyte Apoptosis in Pressure Overloaded Myocardium: Possible Role of Calpain-Mediated Gelsolin Cleavage Journal of Cardiac Failure. 13: S97. DOI: 10.1016/J.Cardfail.2007.06.726 |
0.337 |
|
2006 |
Balasubramanian S, Mani S, Shiraishi H, Johnston RK, Yamane K, Willey CD, Cooper G, Tuxworth WJ, Kuppuswamy D. Enhanced ubiquitination of cytoskeletal proteins in pressure overloaded myocardium is accompanied by changes in specific E3 ligases. Journal of Molecular and Cellular Cardiology. 41: 669-79. PMID 16928382 DOI: 10.1016/J.Yjmcc.2006.04.022 |
0.644 |
|
2006 |
Palanisamy AP, Willey CD, Kuppuswamy D. A82. Bmx and c-Src mediates phosphorylation of p130Cas during cardiac hypertrophy Journal of Molecular and Cellular Cardiology. 40: 891. DOI: 10.1016/J.Yjmcc.2006.03.360 |
0.749 |
|
2005 |
Cheng G, Qiao F, Gallien TN, Kuppuswamy D, Cooper G. Inhibition of beta-adrenergic receptor trafficking in adult cardiocytes by MAP4 decoration of microtubules. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1193-202. PMID 15528234 DOI: 10.1152/Ajpheart.00109.2004 |
0.302 |
|
2003 |
Balasubramanian S, Kuppuswamy D. RGD-containing peptides activate S6K1 through beta3 integrin in adult cardiac muscle cells. The Journal of Biological Chemistry. 278: 42214-24. PMID 12909616 DOI: 10.1074/Jbc.M303428200 |
0.594 |
|
2003 |
Takahashi M, Shiraishi H, Ishibashi Y, Blade KL, McDermott PJ, Menick DR, Kuppuswamy D, Cooper G. Phenotypic consequences of beta1-tubulin expression and MAP4 decoration of microtubules in adult cardiocytes. American Journal of Physiology. Heart and Circulatory Physiology. 285: H2072-83. PMID 12855424 DOI: 10.1152/Ajpheart.00396.2003 |
0.308 |
|
2003 |
Willey CD, Balasubramanian S, RodrÃguez Rosas MC, Ross RS, Kuppuswamy D. Focal complex formation in adult cardiomyocytes is accompanied by the activation of beta3 integrin and c-Src. Journal of Molecular and Cellular Cardiology. 35: 671-83. PMID 12788385 DOI: 10.1016/S0022-2828(03)00112-3 |
0.679 |
|
2003 |
Basuroy S, Sheth P, Kuppuswamy D, Balasubramanian S, Ray RM, Rao RK. Expression of kinase-inactive c-Src delays oxidative stress-induced disassembly and accelerates calcium-mediated reassembly of tight junctions in the Caco-2 cell monolayer. The Journal of Biological Chemistry. 278: 11916-24. PMID 12547828 DOI: 10.1074/jbc.M211710200 |
0.335 |
|
2002 |
Cheng G, Iijima Y, Ishibashi Y, Kuppuswamy D, Cooper G. Inhibition of G protein-coupled receptor trafficking in neuroblastoma cells by MAP 4 decoration of microtubules. American Journal of Physiology. Heart and Circulatory Physiology. 283: H2379-88. PMID 12388311 DOI: 10.1152/Ajpheart.00410.2002 |
0.303 |
|
2002 |
Kuppuswamy D. Importance of integrin signaling in myocyte growth and survival. Circulation Research. 90: 1240-2. PMID 12089060 DOI: 10.1161/01.Res.0000025080.78636.23 |
0.488 |
|
2002 |
Iijima Y, Laser M, Shiraishi H, Willey CD, Sundaravadivel B, Xu L, McDermott PJ, Kuppuswamy D. c-Raf/MEK/ERK pathway controls protein kinase C-mediated p70S6K activation in adult cardiac muscle cells. The Journal of Biological Chemistry. 277: 23065-75. PMID 11940578 DOI: 10.1074/Jbc.M200328200 |
0.748 |
|
2000 |
Laser M, Willey CD, Jiang W, Cooper G, Menick DR, Zile MR, Kuppuswamy D. Integrin activation and focal complex formation in cardiac hypertrophy. The Journal of Biological Chemistry. 275: 35624-30. PMID 10958798 DOI: 10.1074/Jbc.M006124200 |
0.746 |
|
1999 |
Nagai T, Laser M, Baicu CF, Zile MR, Cooper IV G, Kuppuswamy D. Beta3-integrin-mediated focal adhesion complex formation: Adult cardiocytes embedded in three-dimensional polymer matrices American Journal of Cardiology. 83. PMID 10750585 |
0.307 |
|
1999 |
Kasi VS, Kuppuswamy D. Inhibition of Src family kinases by a combinatorial action of 5'-AMP and small heat shock proteins, identified from the adult heart Molecular and Cellular Biology. 19: 6858-6871. PMID 10490624 DOI: 10.1128/Mcb.19.10.6858 |
0.522 |
|
1999 |
Narishige T, Blade KL, Ishibashi Y, Nagai T, Hamawaki M, Menick DR, Kuppuswamy D, Cooper IV G. Cardiac hypertrophic and developmental regulation of the β-tubulin multigene family Journal of Biological Chemistry. 274: 9692-9697. PMID 10092657 DOI: 10.1074/Jbc.274.14.9692 |
0.377 |
|
1998 |
Laser M, Kasi VS, Hamawaki M, Cooper IV G, Kerr CM, Kuppuswamy D. Differential activation of p70 and p85 S6 kinase isoforms during cardiac hypertrophy in the adult mammal Journal of Biological Chemistry. 273: 24610-24619. PMID 9733756 DOI: 10.1074/Jbc.273.38.24610 |
0.547 |
|
1997 |
Sato H, Nagai T, Kuppuswamy D, Narishige T, Koide M, Menick DR, Cooper IV G. Microtubule stabilization in pressure overload cardiac hypertrophy Journal of Cell Biology. 139: 963-973. PMID 9362514 DOI: 10.1083/Jcb.139.4.963 |
0.382 |
|
1997 |
Kuppuswamy D, Kerr C, Narishige T, Kasi VS, Menick DR, Cooper IV G. Association of tyrosine-phosphorylated c-Src with the cytoskeleton of hypertrophying myocardium Journal of Biological Chemistry. 272: 4500-4508. PMID 9020175 DOI: 10.1074/Jbc.272.7.4500 |
0.571 |
|
1996 |
Tagawa H, Rozich JD, Tsutsui H, Narishige T, Kuppuswamy D, Sato H, McDermott PJ, Koide M, Cooper IV G. Basis for increased microtubules in pressure-hypertrophied cardiocytes Circulation. 93: 1230-1243. PMID 8653846 DOI: 10.1161/01.Cir.93.6.1230 |
0.398 |
|
1993 |
Kuppuswamy D, Dalton M, Pike LJ. Serine 1002 is a site of in vivo and in vitro phosphorylation of the epidermal growth factor receptor Journal of Biological Chemistry. 268: 19134-19142. PMID 8360196 |
0.39 |
|
1987 |
Walker DH, Kuppuswamy D, Visvanathan A, Pike LJ. Substrate specificity and kinetic mechanism of human placental insulin receptor/kinase. Biochemistry. 26: 1428-33. PMID 3567178 DOI: 10.1021/Bi00379A033 |
0.317 |
|
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