Noriyuki Kasahara - Publications

Affiliations: 
University of Southern California, Los Angeles, CA, United States 
Area:
Molecular Biology, Genetics, Microbiology Biology, Oncology

166 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Isoda L, Sonoda-Fukuda E, Fujino H, Takarada T, Hasegawa K, Kasahara N, Kubo S. Therapeutic Efficacy of Prodrug Activator Gene Therapy Using Retroviral Replicating Vectors for Human Ovarian Cancer. Anticancer Research. 43: 5311-5317. PMID 38030176 DOI: 10.21873/anticanres.16734  0.414
2023 Fujino H, Sonoda-Fukuda E, Isoda L, Kawabe A, Takarada T, Kasahara N, Kubo S. Retroviral Replicating Vectors Mediated Prodrug Activator Gene Therapy in a Gastric Cancer Model. International Journal of Molecular Sciences. 24. PMID 37834271 DOI: 10.3390/ijms241914823  0.446
2022 Kushiya H, Hiraoka K, Suzuki T, Inoko K, Inagaki A, Niwa H, Sasaki K, Nakamura T, Tsuchikawa T, Shichinohe T, Jolly DJ, Kasahara N, Hirano S. Retroviral Replicating Vector Toca 511 () for Prodrug Activator Gene Therapy of Lung Cancer. Cancers. 14. PMID 36497300 DOI: 10.3390/cancers14235820  0.36
2021 Collins SA, Shah AH, Ostertag D, Kasahara N, Jolly DJ. Clinical development of retroviral replicating vector Toca 511 for gene therapy of cancer. Expert Opinion On Biological Therapy. PMID 33724117 DOI: 10.1080/14712598.2021.1902982  0.438
2020 Montoya ML, Kasahara N, Okada H. Introduction to immunotherapy for brain tumor patients: challenges and future perspectives. Neuro-Oncology Practice. 7: 465-476. PMID 33014387 DOI: 10.1093/Nop/Npaa007  0.387
2020 Chen SH, Sun JM, Chen BM, Lin SC, Chang HF, Collins S, Chang D, Wu SF, Lu YC, Wang W, Chen TC, Kasahara N, Wang HE, Tai CK. Efficient Prodrug Activator Gene Therapy by Retroviral Replicating Vectors Prolongs Survival in an Immune-Competent Intracerebral Glioma Model. International Journal of Molecular Sciences. 21. PMID 32093290 DOI: 10.3390/Ijms21041433  0.731
2019 Inagaki A, Takahashi M, Kamijima S, Hiraoka K, Tam Q, Faure-Kumar E, Treger J, Bogan B, Hacke K, Collins S, Jolly D, Kasahara N. Stem-24. Therapeutic Approach Of Stem Cell Carrying Retroviral Replicating Vectors In Human Glioma Model Neuro-Oncology. 21. DOI: 10.1093/Neuonc/Noz175.997  0.477
2019 Collins S, Kamath P, Matsuura S, Jolly D, Slomovitz B, Kasahara N. Therapeutic efficacy of vocimagene amiretrorepvec (Toca 511) prodrug activator gene therapy in peritoneal carcinomatosis models of ovarian cancer Gynecologic Oncology. 154: e29-e30. DOI: 10.1016/J.Ygyno.2019.03.231  0.397
2018 Kubo S, Takagi-Kimura M, Tagawa M, Kasahara N. Dual-vector prodrug activator gene therapy using retroviral replicating vectors. Cancer Gene Therapy. PMID 30348946 DOI: 10.1038/S41417-018-0051-0  0.533
2018 Kubo S, Takagi-Kimura M, Kasahara N. Efficient tumor transduction and antitumor efficacy in experimental human osteosarcoma using retroviral replicating vectors. Cancer Gene Therapy. PMID 30042500 DOI: 10.1038/S41417-018-0037-Y  0.556
2018 Cloughesy TF, Landolfi J, Vogelbaum MA, Ostertag D, Elder JB, Bloomfield S, Carter B, Chen CC, Kalkanis SN, Kesari S, Lai A, Lee IY, Liau LM, Mikkelsen T, Nghiemphu P, ... ... Kasahara N, et al. Durable Complete Responses in Some Recurrent High Grade Glioma Patients Treated with Toca 511 & Toca FC. Neuro-Oncology. PMID 29762717 DOI: 10.1093/Neuonc/Noy075  0.365
2018 Inoko K, Hiraoka K, Inagaki A, Takahashi M, Kushibiki T, Hontani K, Takano H, Sato S, Takeuchi S, Nakamura T, Tsuchikawa T, Shichinohe T, Gruber HE, Jolly DJ, Kasahara N, et al. Therapeutic activity of retroviral replicating vector-mediated prodrug activator gene therapy for pancreatic cancer. Cancer Gene Therapy. PMID 29735994 DOI: 10.1038/S41417-018-0020-7  0.502
2018 Yagiz K, Rodriguez-Aguirre ME, Lopez Espinoza F, Montellano TT, Mendoza D, Mitchell LA, Ibanez CE, Kasahara N, Gruber HE, Jolly DJ, Robbins JM. A Retroviral Replicating Vector Encoding Cytosine Deaminase and 5-FC Induces Immune Memory in Metastatic Colorectal Cancer Models. Molecular Therapy Oncolytics. 8: 14-26. PMID 29322091 DOI: 10.1016/J.Omto.2017.12.001  0.408
2018 Grosso J, Collins S, Inagaki A, Slomovitz B, Kasahara N. Abstract 5927: Assessing the efficacy of a novel gene therapy approach for treating ovarian cancer: Combination RRV-mediated prodrug activated suicide gene therapy Cancer Research. 78: 5927-5927. DOI: 10.1158/1538-7445.Am2018-5927  0.523
2017 Shah AH, Jusué-Torres I, Ivan ME, Komotar RJ, Kasahara N. Pathogens and glioma: a history of unexpected discoveries ushering in novel therapy. Journal of Neurosurgery. 1-8. PMID 28598280 DOI: 10.3171/2016.12.Jns162123  0.345
2017 Qin Y, Takahashi M, Sheets K, Soto H, Tsui J, Pelargos P, Antonios JP, Kasahara N, Yang I, Prins RM, Braun J, Gordon LK, Wadehra M. Epithelial membrane protein-2 (EMP2) promotes angiogenesis in glioblastoma multiforme. Journal of Neuro-Oncology. PMID 28597184 DOI: 10.1007/S11060-017-2507-8  0.358
2017 Mitchell LA, Lopez Espinoza F, Mendoza D, Kato Y, Inagaki A, Hiraoka K, Kasahara N, Gruber HE, Jolly DJ, Robbins JM. Toca 511 gene transfer and treatment with the prodrug, 5-fluorocytosine, promotes durable antitumor immunity in a mouse glioma model. Neuro-Oncology. PMID 28387849 DOI: 10.1093/Neuonc/Nox037  0.416
2017 Hiraoka K, Inagaki A, Kato Y, Huang TT, Mitchell LA, Kamijima S, Takahashi M, Matsumoto H, Hacke K, Kruse CA, Ostertag D, Robbins JM, Gruber HE, Jolly DJ, Kasahara N. Retroviral replicating vector-mediated gene therapy achieves long-term control of tumor recurrence and leads to durable anticancer immunity. Neuro-Oncology. PMID 28387831 DOI: 10.1093/Neuonc/Nox038  0.519
2017 Feister K, Collins S, Kasahara N, Slomovitz B. Abstract B36: Compassionate use of an oncolytic adenovirus in a Stage IV treatment-refractory ovarian cancer patient Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-B36  0.415
2017 Collins S, Inagaki A, Tangney M, Kasahara N. Abstract B03: Development of retroviral replicating vectors expressing codon-optimized nitroreductase for prodrug activator gene therapy in human glioma models Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-B03  0.565
2017 Grosso J, Collins S, Inagaki A, Matsuura S, Slomovitz B, Ince T, Kasahara N. Abstract A42: Alternate pseudotypes overcome receptor interference and enable combination suicide gene therapy with retroviral replicating vectors Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-A42  0.544
2017 Collins SA, Kamath P, Grosso J, Matsuura S, Xu X, Ince T, Jolly DJ, Slomovitz B, Kasahara N. Prodrug Activator Gene Therapy of Ovarian Cancer using a Retroviral Replicating Vector Gynecologic Oncology. 147: 197. DOI: 10.1016/J.Ygyno.2017.07.028  0.456
2017 Collins SA, Inagaki A, Grosso J, Matsuura S, Kamath PN, Xu X, Ince TA, Slomovitz B, Kasahara N. Vocimagene amiretrorepvec (Toca 511) for prodrug activator gene therapy in ovarian cancer models Gynecologic Oncology. 145: 97. DOI: 10.1016/J.Ygyno.2017.03.228  0.384
2017 Grosso J, Inagaki A, Collins SA, Matsuura S, Kamath PN, Ince TA, Kasahara N, Slomovitz B. Pseudotyped retroviral replicating vectors for combination prodrug activator gene therapy of ovarian cancer Gynecologic Oncology. 145: 95. DOI: 10.1016/J.Ygyno.2017.03.222  0.459
2016 Kozlowska AK, Tseng HC, Kaur K, Topchyan P, Inagaki A, Bui VT, Kasahara N, Cacalano N, Jewett A. Resistance to cytotoxicity and sustained release of interleukin-6 and interleukin-8 in the presence of decreased interferon-γ after differentiation of glioblastoma by human natural killer cells. Cancer Immunology, Immunotherapy : Cii. PMID 27439500 DOI: 10.1007/S00262-016-1866-X  0.315
2016 Cloughesy TF, Landolfi J, Hogan DJ, Bloomfield S, Carter B, Chen CC, Elder JB, Kalkanis SN, Kesari S, Lai A, Lee IY, Liau LM, Mikkelsen T, Nghiemphu PL, Piccioni D, ... ... Kasahara N, et al. Phase 1 trial of vocimagene amiretrorepvec and 5-fluorocytosine for recurrent high-grade glioma. Science Translational Medicine. 8: 341ra75. PMID 27252174 DOI: 10.1126/Scitranslmed.Aad9784  0.322
2016 Lin AH, Liu Y, Burrascano C, Cunanan K, Logg CR, Robbins JM, Kasahara N, Gruber H, Ibañez C, Jolly DJ. Extensive Replication of a Retroviral Replicating Vector Can Expand the A Bulge in the Encephalomyocarditis Virus Internal Ribosome Entry Site and Change Translation Efficiency of the Downstream Transgene. Human Gene Therapy Methods. PMID 26918465 DOI: 10.1089/Hgtb.2015.131  0.727
2016 Inoko K, Hiraoka K, Inagaki A, Takahashi M, Kushibiki T, Hontani K, Takano H, Sato S, Nakamura T, Tsuchikawa T, Shichinohe T, Jolly DJ, Kasahara N, Hirano S. 673. Therapeutic Efficacy of Retroviral Replicating Vector (RRV) -Mediated Prodrug Activator Gene Therapy for Pancreatic Cancer Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33481-5  0.502
2016 Kubo S, Mawatari-Furukawa Y, Kasahara N. 217. Combinatorial Anti-Angiogenic Gene Therapy in a Human Malignant Mesothelioma Model Molecular Therapy. 24. DOI: 10.1016/S1525-0016(16)33026-X  0.456
2016 Jolly DJ, Robbins JM, Ostertag D, Ibañez C, Kasahara N, Gruber H, Kalkanis SN, Vogelbaum M, Aghi MK, Cloughesy T, Chu A, Das A, Skillings J. 61. Ascending Dose Trials of a Retroviral Replicating Vector (Toca 511) in Patients with Recurrent High-Grade Glioma: Clinical Update, Molecular Analyses, and Proposed Mechanism of Action Molecular Therapy. 24: S27. DOI: 10.1016/S1525-0016(16)32870-2  0.419
2015 Tseng HC, Inagaki A, Bui VT, Cacalano N, Kasahara N, Man YG, Jewett A. Differential Targeting of Stem Cells and Differentiated Glioblastomas by NK Cells. Journal of Cancer. 6: 866-76. PMID 26284138 DOI: 10.7150/Jca.11527  0.346
2015 Kubo S, Takagi-Kimura M, Kasahara N. Combinatorial anti-angiogenic gene therapy in a human malignant mesothelioma model. Oncology Reports. 34: 633-8. PMID 26082103 DOI: 10.3892/Or.2015.4058  0.455
2015 Iwabuchi M, Narita M, Uchiyama T, Iwaya S, Oiwa E, Nishizawa Y, Hashimoto S, Bonehill A, Kasahara N, Takizawa J, Takahashi M. Enhancement of the antigen‑specific cytotoxic T lymphocyte‑inducing ability in the PMDC11 leukemic plasmacytoid dendritic cell line via lentiviral vector‑mediated transduction of the caTLR4 gene. Molecular Medicine Reports. 12: 2443-50. PMID 25936433 DOI: 10.3892/Mmr.2015.3685  0.37
2015 Erickson KL, Hickey MJ, Kato Y, Malone CC, Owens GC, Prins RM, Liau LM, Kasahara N, Kruse CA. Radial mobility and cytotoxic function of retroviral replicating vector transduced, non-adherent alloresponsive T lymphocytes. Journal of Visualized Experiments : Jove. PMID 25741775 DOI: 10.3791/52416  0.402
2015 Awe JP, Gschweng EH, Vega-Crespo A, Voutila J, Williamson MH, Truong B, Kohn DB, Kasahara N, Byrne JA. Putative immunogenicity expression profiling using human pluripotent stem cells and derivatives. Stem Cells Translational Medicine. 4: 136-45. PMID 25575527 DOI: 10.5966/Sctm.2014-0117  0.373
2015 Huang TT, Parab S, Burnett R, Diago O, Ostertag D, Hofman FM, Espinoza FL, Martin B, Ibañez CE, Kasahara N, Gruber HE, Pertschuk D, Jolly DJ, Robbins JM. Intravenous administration of retroviral replicating vector, Toca 511, demonstrates therapeutic efficacy in orthotopic immune-competent mouse glioma model. Human Gene Therapy. 26: 82-93. PMID 25419577 DOI: 10.1089/Hum.2014.100  0.48
2015 Inagaki A, Hiraoka K, Kamijima S, Robbins JM, Jolly DJ, Gruber HE, Kasahara N. 629. Preclinical Evaluation of Prodrug Activator Gene Therapy by Retroviral Replicating Vectors (RRV) in Experimental Models of Breast Cancer CNS Metastasis Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34238-1  0.508
2015 Kubo S, Takagi-Kimura M, Logg CR, Hermann K, Kasahara N. 536. Dual-Vector Prodrug Activator Gene Therapy Using Retroviral Replicating Vectors Derived from Amphotropic Murine Leukemia Virus and Gibbon Ape Leukemia Virus Molecular Therapy. 23: S215. DOI: 10.1016/S1525-0016(16)34145-4  0.782
2015 Yagiz K, Rodriguez-Aguirre ME, Espinoza FL, Martin B, Huang TT, Ibanez C, Ostertag D, Kasahara N, Gruber HE, Jolly DJ, Robbins JM. 531. Intravenous Delivery of Toca 511 Gene Therapy in Combination with 5-Fluorocytosine for Intratumoral Production of 5-Fluorouracil in a Colon Cancer Metastasis Model Molecular Therapy. 23. DOI: 10.1016/S1525-0016(16)34140-5  0.448
2015 Collins SA, Logg CR, Inagaki A, Kamijima S, Lehouritis P, Searle PF, Tangney M, Kasahara N. 433. Sequence-Optimized Nitroreductase for Retroviral Replicating Vector (RRV) Mediated Prodrug Activator Gene Therapy in Human Glioma Models Molecular Therapy. 23: S171. DOI: 10.1016/S1525-0016(16)34042-4  0.797
2015 Hacke K, Treger J, Bogan B, Rezek V, Narukawa M, Shimizu S, Liu P, Reik A, Lieber A, Crooks G, Kohn D, An DS, Kitchen S, Gregory P, Cost G, ... ... Kasahara N, et al. A novel in vivo chemoselection strategy for genetically modified hematopoietic stem cells Cytotherapy. 17: S52. DOI: 10.1016/J.Jcyt.2015.03.486  0.465
2015 Kato Y, Hickey M, Treger J, Erickson K, Haga K, Malone C, Inagaki A, Kruse C, Kasahara N. RRV-mediated prodrug activator gene therapy combined with alloreactive T cell immunotherapy for malignancies in the CNS Cytotherapy. 17. DOI: 10.1016/J.Jcyt.2015.03.484  0.407
2015 Takahashi M, Uchiyama T, Iwaya S, Oiwa E, Nishizawa Y, Hashimoto S, Bonehill A, Kasahara N, Narita M. Leukemic plasmacytoid dendritic cell line transduced with caTLR4 gene as a potent antigen presenting cells for immunotherapy Cytotherapy. 17. DOI: 10.1016/J.Jcyt.2015.03.363  0.381
2014 Burnett R, Ibañez CE, Pettersson PL, Chen CI, Parab S, Huang T, Robbins J, Bankiewicz K, Aghi M, Logg C, Kasahara N, Pertschuk D, Gruber HE, Jolly DJ. Maintaining therapeutic activity in the operating room: compatibility of a gamma-retroviral replicating vector with clinical materials and biofluids. Molecular Therapy. Methods & Clinical Development. 1: 14024. PMID 26015967 DOI: 10.1038/Mtm.2014.24  0.709
2014 Veena MS, Wilken R, Zheng JY, Gholkar A, Venkatesan N, Vira D, Ahmed S, Basak SK, Dalgard CL, Ravichandran S, Batra RK, Kasahara N, Elashoff D, Fishbein MC, Whitelegge JP, et al. p16 Protein and gigaxonin are associated with the ubiquitination of NFκB in cisplatin-induced senescence of cancer cells. The Journal of Biological Chemistry. 289: 34921-37. PMID 25331947 DOI: 10.1074/Jbc.M114.568543  0.358
2014 Takahashi M, Valdes G, Hiraoka K, Inagaki A, Kamijima S, Micewicz E, Gruber HE, Robbins JM, Jolly DJ, McBride WH, Iwamoto KS, Kasahara N. Radiosensitization of gliomas by intracellular generation of 5-fluorouracil potentiates prodrug activator gene therapy with a retroviral replicating vector. Cancer Gene Therapy. 21: 405-10. PMID 25301172 DOI: 10.1038/Cgt.2014.38  0.505
2014 Lin AH, Timberlake N, Logg CR, Liu Y, Kamijima S, Diago O, Wong K, Gammon DK, Ostertag D, Hacke K, Yang EC, Gruber H, Kasahara N, Jolly DJ. MicroRNA 142-3p attenuates spread of replicating retroviral vector in hematopoietic lineage-derived cells while maintaining an antiviral immune response. Human Gene Therapy. 25: 759-71. PMID 24825189 DOI: 10.1089/Hum.2012.216  0.766
2014 Matsumoto H, Haga K, Ohno I, Hiraoka K, Kimura T, Hermann K, Kasahara N, Anton P, McGowan I. Mucosal gene therapy using a pseudotyped lentivirus vector encoding murine interleukin-10 (mIL-10) suppresses the development and relapse of experimental murine colitis. Bmc Gastroenterology. 14: 68. PMID 24712338 DOI: 10.1186/1471-230X-14-68  0.427
2014 Qin Y, Fu M, Takahashi M, Iwanami A, Kuga D, Rao RG, Sudhakar D, Huang T, Kiyohara M, Torres K, Dillard C, Inagaki A, Kasahara N, Goodglick L, Braun J, et al. Epithelial membrane protein-2 (EMP2) activates Src protein and is a novel therapeutic target for glioblastoma. The Journal of Biological Chemistry. 289: 13974-85. PMID 24644285 DOI: 10.1074/Jbc.M113.543728  0.422
2014 Mintz PJ, Huang KW, Reebye V, Nteliopoulos G, Lai HS, Sætrom P, Kasahara N, Jensen S, Pai M, Gordon MY, Marley SB, Behan R, Spalding DR, Haoudi A, Emara MM, et al. Exploiting human CD34+ stem cell-conditioned medium for tissue repair. Molecular Therapy : the Journal of the American Society of Gene Therapy. 22: 149-59. PMID 23985698 DOI: 10.1038/Mt.2013.194  0.332
2014 Reebye V, Sætrom P, Mintz PJ, Huang KW, Swiderski P, Peng L, Liu C, Liu X, Lindkaer-Jensen S, Zacharoulis D, Kostomitsopoulos N, Kasahara N, Nicholls JP, Jiao LR, Pai M, et al. Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesis in vivo. Hepatology (Baltimore, Md.). 59: 216-27. PMID 23929703 DOI: 10.1002/Hep.26669  0.358
2014 Kruse C, Liau L, Prins R, Antonios J, Ha E, Kasahara N, Soto H, Yang I. Chronic inflammation drives glioma growth: cellular and molecular factors responsible for an immunosuppressive microenvironment Neuroimmunology and Neuroinflammation. 1: 66. DOI: 10.4103/2347-8659.139717  0.353
2014 Robbins JM, Huang TT, Jolly DJ, Kasahara N, Aghi MK, Vogelbaum MA, Cloughesy TF, Chang SM, Kesari S, Mikkelsen T, Kalkanis SN, Landolfi JC, Elder JB, Chiocca EA, Gruber HE, et al. Ascending dose trials of a retroviral replicating vector (Toca 511) in patients with recurrent high-grade glioma. Journal of Clinical Oncology. 32: 3078-3078. DOI: 10.1200/Jco.2014.32.15_Suppl.3078  0.394
2014 Conway A, Laganière J, Paschon DE, Hacke K, Kasahara N, Gregory PD, Holmes MC, Cost GJ. HPRT As a Selectable Safe Harbor for Transgenesis Blood. 124: 4796-4796. DOI: 10.1182/Blood.V124.21.4796.4796  0.454
2014 Rodriguez-Aguirre ME, Espinoza FL, Martin B, Yadiz K, Huang TT, Ibanez CE, Ostertag DG, Kasahara N, Gruber HE, Jolly DJ, Robbins JM. Abstract 708: Toca 511 gene therapy in combination with 5-fluorocytosine for intratumoral production of 5-fluorouracil in a colon cancer metastasis model Cancer Research. 74: 708-708. DOI: 10.1158/1538-7445.Am2014-708  0.38
2014 Erickson KL, Malone CC, Hickey MJ, Owens GC, Kato Y, Prins RM, Kasahara N, Kruse CA. Abstract 1660: Retroviral replicating vector transduced alloresponsive T lymphocytes retain mobility and cytotoxic functionalities Cancer Research. 74: 1660-1660. DOI: 10.1158/1538-7445.Am2014-1660  0.441
2014 Takahashi M, Valdes G, Inagaki A, Kamijima S, Hiraoka K, Micewicz E, McBride WH, Iwamoto KS, Hermann K, Collins S, Tam Q, Gruber HE, Robbins JM, Jolly DJ, Kasahara N. ET-60 * ENHANCED THERAPEUTIC EFFICACY OF PRODRUG ACTIVATOR GENE THERAPY WITH A NON-LYTIC RETROVIRAL REPLICATING VECTOR (TOCA 511) COMBINED WITH RADIATION THERAPY IN EXPERIMENTAL GLIOMA Neuro-Oncology. 16: v92-v92. DOI: 10.1093/Neuonc/Nou255.57  0.372
2014 Inagaki A, Hiraoka K, Kamijima S, Robbins J, Jolly D, Gruber H, Kasahara N. Et-23Therapeutic Efficacy Of Retroviral Replicating Vectors In Human Breast Cancer Cns Metastasis Model Neuro-Oncology. 16. DOI: 10.1093/Neuonc/Nou255.23  0.506
2014 Collins S, Logg C, Inagaki A, Kamijima S, Lehouritis P, Searle P, Tangney M, Kasahara N. ET-13 * RETROVIRAL REPLICATING VECTOR (RRV)-MEDIATED PRODRUG ACTIVATOR GENE THERAPY WITH CODON-OPTIMIZED NITROREDUCTASE IN EXPERIMENTAL GLIOMA Neuro-Oncology. 16: v81-v82. DOI: 10.1093/Neuonc/Nou255.13  0.798
2013 Perez OD, Logg CR, Hiraoka K, Diago O, Burnett R, Inagaki A, Jolson D, Amundson K, Buckley T, Lohse D, Lin A, Burrascano C, Ibanez C, Kasahara N, Gruber HE, et al. Erratum: Design and selection of toca 511 for clinical use: Modified retroviral replicating vector with improved stability and gene expression (Molecular Therapy (2012) 20 (1689-1698) DOI:10.1038/mt.2012.83) Molecular Therapy. 21. PMID 28160846 DOI: 10.1038/Mt.2013.6  0.733
2013 Lemp NA, Haga K, Hacke K, Treger JA, Bogan BT, Faure-Kumar E, Logg CR, Kruse CA, Cicciarelli JC, Kasahara N. Reduction of HLA class I expression by ribonucleic acid interference mitigates allogenicity of human primary and Immortalized cells. Clinical Transplants. 93-101. PMID 25095496  0.702
2013 Hickey MJ, Kasahara N, Mueller BM, Kruse CA. Combining cellular and gene therapy approaches for treatment of intracranial tumors. Oncoimmunology. 2: e25989. PMID 24244896 DOI: 10.4161/Onci.25989  0.438
2013 Kubo S, Takagi-Kimura M, Logg CR, Kasahara N. Highly efficient tumor transduction and antitumor efficacy in experimental human malignant mesothelioma using replicating gibbon ape leukemia virus. Cancer Gene Therapy. 20: 671-7. PMID 24201868 DOI: 10.1038/Cgt.2013.67  0.792
2013 Pham LK, Liang M, Adisetiyo HA, Liao CP, Cohen MB, Tahara SM, Frenkel B, Kasahara N, Roy-Burman P. Contextual effect of repression of bone morphogenetic protein activity in prostate cancer. Endocrine-Related Cancer. 20: 861-74. PMID 24042462 DOI: 10.1530/Erc-13-0100  0.404
2013 Huang TT, Hlavaty J, Ostertag D, Espinoza FL, Martin B, Petznek H, Rodriguez-Aguirre M, Ibañez CE, Kasahara N, Gunzburg W, Gruber HE, Pertschuk D, Jolly DJ, Robbins JM. Toca 511 gene transfer and 5-fluorocytosine in combination with temozolomide demonstrates synergistic therapeutic efficacy in a temozolomide-sensitive glioblastoma model. Cancer Gene Therapy. 20: 544-51. PMID 23969884 DOI: 10.1038/Cgt.2013.51  0.391
2013 Takagi-Kimura M, Yamano T, Tamamoto A, Okamura N, Okamura H, Hashimoto-Tamaoki T, Tagawa M, Kasahara N, Kubo S. Enhanced antitumor efficacy of fiber-modified, midkine promoter-regulated oncolytic adenovirus in human malignant mesothelioma. Cancer Science. 104: 1433-9. PMID 23962292 DOI: 10.1111/Cas.12267  0.393
2013 Hickey MJ, Malone CC, Erickson KL, Lin A, Soto H, Ha ET, Kamijima S, Inagaki A, Takahashi M, Kato Y, Kasahara N, Mueller BM, Kruse CA. Combined alloreactive CTL cellular therapy with prodrug activator gene therapy in a model of breast cancer metastatic to the brain. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 4137-48. PMID 23780889 DOI: 10.1158/1078-0432.Ccr-12-3735  0.419
2013 Hacke K, Treger JA, Bogan BT, Schiestl RH, Kasahara N. Genetic modification of mouse bone marrow by lentiviral vector-mediated delivery of hypoxanthine-Guanine phosphoribosyltransferase short hairpin RNA confers chemoprotection against 6-thioguanine cytotoxicity Transplantation Proceedings. 45: 2040-2044. PMID 23769104  0.31
2013 Reebye V, Sætrom P, Mintz PJ, Rossi JJ, Kasahara N, Nteliopoulos G, Nicholls J, Haoudi A, Gordon M, Habib NA. A Short-activating RNA Oligonucleotide Targeting the Islet β-cell Transcriptional Factor MafA in CD34(+) Cells. Molecular Therapy. Nucleic Acids. 2: e97. PMID 23736775 DOI: 10.1038/Mtna.2013.23  0.311
2013 Yin D, Zhai Y, Gruber HE, Ibanez CE, Robbins JM, Kells AP, Kasahara N, Forsayeth J, Jolly DJ, Bankiewicz KS. Convection-enhanced delivery improves distribution and efficacy of tumor-selective retroviral replicating vectors in a rodent brain tumor model. Cancer Gene Therapy. 20: 336-41. PMID 23703472 DOI: 10.1038/Cgt.2013.25  0.408
2013 Lam P, Khan G, Stripecke R, Hui KM, Kasahara N, Peng K, Guinn B. The innovative evolution of cancer gene and cellular therapies. Cancer Gene Therapy. 20: 141-149. PMID 23370333 DOI: 10.1038/Cgt.2012.93  0.39
2013 KAMIJIMA S, KIMURA T, HAGA K, HIRAOKA K, INAGAKI A, LOGG C, KAO C, BOCHNER B, KASAHARA N. 328 PROSTATE-TARGETED RETROVIRAL REPLICATING VECTORS FOR PRODRUG-ACTIVATOR GENE THERAPY Journal of Urology. 189. DOI: 10.1016/J.Juro.2013.02.1713  0.731
2012 Voutila J, Sætrom P, Mintz P, Sun G, Alluin J, Rossi JJ, Habib NA, Kasahara N. Gene Expression Profile Changes After Short-activating RNA-mediated Induction of Endogenous Pluripotency Factors in Human Mesenchymal Stem Cells. Molecular Therapy. Nucleic Acids. 1: e35. PMID 23344177 DOI: 10.1038/Mtna.2012.20  0.416
2012 Janson C, Kasahara N, Prendergast GC, Colicelli J. RIN3 is a negative regulator of mast cell responses to SCF. Plos One. 7: e49615. PMID 23185384 DOI: 10.1371/Journal.Pone.0049615  0.332
2012 Yamahira A, Narita M, Ishii K, Jayathilake RM, Iwabuchi M, Satoh N, Uchiyama T, Taniguchi T, Hashimoto S, Kasahara N, Faure E, Bogan B, Takizawa J, Sone H, Takahashi M. Enhancement of antigen presenting ability in the leukemic plasmacytoid dendritic cell line (PMDC05) by lentiviral vector-mediated transduction of CD80 gene. Leukemia Research. 36: 1541-6. PMID 23040531 DOI: 10.1016/J.Leukres.2012.09.002  0.403
2012 Lemp NA, Hiraoka K, Kasahara N, Logg CR. Cryptic transcripts from a ubiquitous plasmid origin of replication confound tests for cis-regulatory function. Nucleic Acids Research. 40: 7280-90. PMID 22618870 DOI: 10.1093/Nar/Gks451  0.694
2012 Perez OD, Logg CR, Hiraoka K, Diago O, Burnett R, Inagaki A, Jolson D, Amundson K, Buckley T, Lohse D, Lin A, Burrascano C, Ibanez C, Kasahara N, Gruber HE, et al. Design and selection of Toca 511 for clinical use: modified retroviral replicating vector with improved stability and gene expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 20: 1689-98. PMID 22547150 DOI: 10.1038/Mt.2012.83  0.758
2012 Logg CR, Robbins JM, Jolly DJ, Gruber HE, Kasahara N. Retroviral replicating vectors in cancer. Methods in Enzymology. 507: 199-228. PMID 22365776 DOI: 10.1016/B978-0-12-386509-0.00011-9  0.778
2012 Cronin M, Akin AR, Collins SA, Meganck J, Kim JB, Baban CK, Joyce SA, van Dam GM, Zhang N, van Sinderen D, O'Sullivan GC, Kasahara N, Gahan CG, Francis KP, Tangney M. High resolution in vivo bioluminescent imaging for the study of bacterial tumour targeting. Plos One. 7: e30940. PMID 22295120 DOI: 10.1371/Journal.Pone.0030940  0.325
2012 Collins SA, Hiraoka K, Inagaki A, Kasahara N, Tangney M. PET imaging for gene & cell therapy. Current Gene Therapy. 12: 20-32. PMID 22263921 DOI: 10.2174/156652312799789271  0.372
2012 Ostertag D, Amundson KK, Lopez Espinoza F, Martin B, Buckley T, Galvão da Silva AP, Lin AH, Valenta DT, Perez OD, Ibañez CE, Chen CI, Pettersson PL, Burnett R, Daublebsky V, Hlavaty J, ... ... Kasahara N, et al. Brain tumor eradication and prolonged survival from intratumoral conversion of 5-fluorocytosine to 5-fluorouracil using a nonlytic retroviral replicating vector. Neuro-Oncology. 14: 145-59. PMID 22070930 DOI: 10.1093/Neuonc/Nor199  0.452
2012 Nitsche C, Edderkaoui M, Moore RM, Eibl G, Kasahara N, Treger J, Grippo PJ, Mayerle J, Lerch MM, Gukovskaya AS. The phosphatase PHLPP1 regulates Akt2, promotes pancreatic cancer cell death, and inhibits tumor formation. Gastroenterology. 142: 377-87.e1-5. PMID 22044669 DOI: 10.1053/J.Gastro.2011.10.026  0.367
2012 Hacke K, Szakmary A, Cuddihy AR, Rozengurt N, Lemp NA, Aubrecht J, Lawson GW, Rao NP, Crooks GM, Schiestl RH, Kasahara N. Combined preconditioning and in vivo chemoselection with 6-thioguanine alone achieves highly efficient reconstitution of normal hematopoiesis with HPRT-deficient bone marrow. Experimental Hematology. 40: 3-13.e3. PMID 22001673 DOI: 10.1016/J.Exphem.2011.09.009  0.311
2011 Kawasaki Y, Tamamoto A, Takagi-Kimura M, Maeyama Y, Yamaoka N, Terada N, Okamura H, Kasahara N, Kubo S. Replication-competent retrovirus vector-mediated prodrug activator gene therapy in experimental models of human malignant mesothelioma Cancer Gene Therapy. 18: 571-578. PMID 21660062 DOI: 10.1038/Cgt.2011.25  0.565
2011 Pincha M, Salguero G, Wedekind D, Sundarasetty BS, Lin A, Kasahara N, Brugman MH, Jirmo AC, Modlich U, Gutzmer R, Büsche G, Ganser A, Stripecke R. Lentiviral vectors for induction of self-differentiation and conditional ablation of dendritic cells. Gene Therapy. 18: 750-64. PMID 21412283 DOI: 10.1038/Gt.2011.15  0.426
2011 Kubo S, Haga K, Tamamoto A, Palmer DJ, Ng P, Okamura H, Kasahara N. Adenovirus-retrovirus hybrid vectors achieve highly enhanced tumor transduction and antitumor efficacy in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 19: 76-82. PMID 20808291 DOI: 10.1038/Mt.2010.182  0.578
2011 Hiraoka K, Inagaki A, Logg CR, Kamijima S, Hui KM, Marini FC, Kasahara N. Abstract 5397: Human mesenchymal stem cell-based cell carrier for tumor-homing delivery of replicating retrovirus vectors in glioblastoma models Cancer Research. 71: 5397-5397. DOI: 10.1158/1538-7445.Am2011-5397  0.74
2011 Kamijima S, Kimura T, Haga K, Hiraoka K, Inagaki A, Logg CR, Kao C, Bochner BH, Ichikawa T, Kasahara N. Abstract 5393: Prodrug activator gene therapy mediated by prostate-specific replicating retrovirus vectors Cancer Research. 71: 5393-5393. DOI: 10.1158/1538-7445.Am2011-5393  0.769
2011 Inagaki A, Hiraoka K, Logg CR, Kamijima S, Ostertag D, Perez OD, Gruber HE, Jolly DJ, Robbins JM, Kasahara N. Abstract 5386: Therapeutic efficacy of RMLV vectors in human and murine glioma models Cancer Research. 71: 5386-5386. DOI: 10.1158/1538-7445.Am2011-5386  0.805
2010 Kubo S, Kawasaki Y, Yamaoka N, Tagawa M, Kasahara N, Terada N, Okamura H. Complete regression of human malignant mesothelioma xenografts following local injection of midkine promoter-driven oncolytic adenovirus. The Journal of Gene Medicine. 12: 681-92. PMID 20635326 DOI: 10.1002/Jgm.1486  0.372
2010 Kimura T, Hiraoka K, Kasahara N, Logg CR. Optimization of enzyme-substrate pairing for bioluminescence imaging of gene transfer using Renilla and Gaussia luciferases. The Journal of Gene Medicine. 12: 528-37. PMID 20527045 DOI: 10.1002/Jgm.1463  0.712
2010 Tai CK, Wang W, Lai YH, Logg CR, Parker WB, Li YF, Hong JS, Sorscher EJ, Chen TC, Kasahara N. Enhanced efficiency of prodrug activation therapy by tumor-selective replicating retrovirus vectors armed with the Escherichia coli purine nucleoside phosphorylase gene. Cancer Gene Therapy. 17: 614-23. PMID 20467451 DOI: 10.1038/Cgt.2010.17  0.829
2010 Matsumoto H, Kimura T, Haga K, Kasahara N, Anton P, McGowan I. Effective in vivo and ex vivo gene transfer to intestinal mucosa by VSV-G-pseudotyped lentiviral vectors. Bmc Gastroenterology. 10: 44. PMID 20459837 DOI: 10.1186/1471-230X-10-44  0.37
2010 Guinn B, Casey G, Möller MG, Kasahara N, O'Sullivan GC, Peng KW, Tangney M. International Society for Cell and Gene Therapy of Cancer 2009 Annual Meeting held in Cork, Ireland. Human Gene Therapy. 21: 9-26. PMID 20017714 DOI: 10.1089/Hum.2009.205  0.395
2010 Kubo S, Kataoka M, Tateno C, Yoshizato K, Kawasaki Y, Kimura T, Faure-Kumar E, Palmer DJ, Ng P, Okamura H, Kasahara N. In vivo stable transduction of humanized liver tissue in chimeric mice via high-capacity adenovirus-lentivirus hybrid vector. Human Gene Therapy. 21: 40-50. PMID 19725756 DOI: 10.1016/J.Ymthe.2006.08.024  0.386
2010 Nitsche CJ, Edderkaoui MM, Eibl GS, Kasahara N, Grippo P, Mayerle J, Lerch MM, Gukovskaya AS. Abstract 3078: PHLPP1 phosphatase dephosphorylates Akt and inhibits tumorogenesis in the orthotopic model of pancreatic cancer Cancer Research. 70: 3078-3078. DOI: 10.1158/1538-7445.Am10-3078  0.382
2009 Hacke K, Falahati R, Flebbe-Rehwaldt L, Kasahara N, Gaensler KM. Suppression of HLA expression by lentivirus-mediated gene transfer of siRNA cassettes and in vivo chemoselection to enhance hematopoietic stem cell transplantation. Immunologic Research. 44: 112-26. PMID 19048410 DOI: 10.1007/S12026-008-8088-Z  0.397
2009 Haga K, Tomioka A, Liao CP, Kimura T, Matsumoto H, Ohno I, Hermann K, Logg CR, Jiao J, Tanaka M, Hirao Y, Wu H, Kruse CA, Roy-Burman P, Kasahara N. PTEN knockout prostate cancer as a model for experimental immunotherapy. The Journal of Urology. 181: 354-62. PMID 19010487 DOI: 10.1016/J.Juro.2008.08.124  0.714
2008 Baranick BT, Lemp NA, Nagashima J, Hiraoka K, Kasahara N, Logg CR. Splicing mediates the activity of four putative cellular internal ribosome entry sites. Proceedings of the National Academy of Sciences of the United States of America. 105: 4733-8. PMID 18326627 DOI: 10.1073/Pnas.0710650105  0.669
2008 Tai CK, Kasahara N. Replication-competent retrovirus vectors for cancer gene therapy. Frontiers in Bioscience : a Journal and Virtual Library. 13: 3083-95. PMID 17981778 DOI: 10.2741/2910  0.744
2008 Cheng JC, Kinjo K, Judelson DR, Chang J, Wu WS, Schmid I, Shankar DB, Kasahara N, Stripecke R, Bhatia R, Landaw EM, Sakamoto KM. CREB is a critical regulator of normal hematopoiesis and leukemogenesis. Blood. 111: 1182-92. PMID 17975014 DOI: 10.1182/Blood-2007-04-083600  0.338
2008 Kasahara N, Lemp N, Houston K, Rhodes C, Musa S, Haga K, Stripecke R, Mendez R, Kruse C, Cicciarelli J. Silencing Of Hla Class I Expression By Lentivirus Vector-Mediated Rna Interference Results In Resistance Of Primary Human Cells To Alloreactive T Cell-Mediated Cytotoxicity: 811 Transplantation. 86: 282-283. DOI: 10.1097/01.Tp.0000332038.63056.D4  0.363
2008 Haga K, Tomioka A, Kimura T, Liao C, Matsumoto H, Ohno I, Logg CR, Hermann KJ, Tanaka M, Uemura H, Hirao Y, Roy-Burman P, Kasahara N. SUICIDE GENE THERAPY USING REPLICATION-COMPETENT RETROVIRUS (RCR) COMBINED WITH TUMOR-SPECIFIC CYTOTOXIC T LYMPHOCYTES (CTLs) FOR PTEN KNOCK-OUT SPONTANEOUS PROSTATE CANCER MODEL Journal of Urology. 179: 41-42. DOI: 10.1016/S0022-5347(08)60126-3  0.738
2007 Kikuchi E, Menendez S, Ozu C, Ohori M, Cordon-Cardo C, Logg CR, Kasahara N, Bochner BH. Highly efficient gene delivery for bladder cancers by intravesically administered replication-competent retroviral vectors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 13: 4511-8. PMID 17671137 DOI: 10.1016/J.Juro.2007.10.016  0.772
2007 Hiraoka K, Kimura T, Logg CR, Tai CK, Haga K, Lawson GW, Kasahara N. Therapeutic efficacy of replication-competent retrovirus vector-mediated suicide gene therapy in a multifocal colorectal cancer metastasis model. Cancer Research. 67: 5345-53. PMID 17545615 DOI: 10.1158/0008-5472.Can-06-4673  0.823
2007 Kimura T, Koya RC, Anselmi L, Sternini C, Wang HJ, Comin-Anduix B, Prins RM, Faure-Kumar E, Rozengurt N, Cui Y, Kasahara N, Stripecke R. Lentiviral vectors with CMV or MHCII promoters administered in vivo: immune reactivity versus persistence of expression. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1390-9. PMID 17505480 DOI: 10.1038/Sj.Mt.6300180  0.412
2007 Logg CR, Baranick BT, Lemp NA, Kasahara N. Adaptive evolution of a tagged chimeric gammaretrovirus: identification of novel cis-acting elements that modulate splicing. Journal of Molecular Biology. 369: 1214-29. PMID 17498744 DOI: 10.1016/J.Jmb.2007.04.026  0.736
2007 Koya RC, Kimura T, Ribas A, Rozengurt N, Lawson GW, Faure-Kumar E, Wang HJ, Herschman H, Kasahara N, Stripecke R. Lentiviral vector-mediated autonomous differentiation of mouse bone marrow cells into immunologically potent dendritic cell vaccines. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 971-80. PMID 17375074 DOI: 10.1038/Mt.Sj.6300126  0.324
2007 Guinn BA, Kasahara N, Farzaneh F, Habib NA, Norris JS, Deisseroth AB. Recent advances and current challenges in tumor immunology and immunotherapy. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 1065-71. PMID 17375068 DOI: 10.1038/Sj.Mt.6300138  0.367
2007 Buscarini M, Quek ML, Gilliam-Hegarich S, Kasahara N, Bochner B. Adenoviral receptor expression of normal bladder and transitional cell carcinoma of the bladder Urologia Internationalis. 78: 160-166. PMID 17293658 DOI: 10.1159/000098076  0.351
2007 Dalba C, Bellier B, Kasahara N, Klatzmann D. Replication-competent vectors and empty virus-like particles: new retroviral vector designs for cancer gene therapy or vaccines. Molecular Therapy : the Journal of the American Society of Gene Therapy. 15: 457-66. PMID 17245356 DOI: 10.1038/Sj.Mt.6300054  0.514
2007 Kikuchi E, Menendez S, Ozu C, Ohori M, Cordon-Cardo C, Logg CR, Kasahara N, Bochner BH. Delivery of replication-competent retrovirus expressing Escherichia coli purine nucleoside phosphorylase increases the metabolism of the prodrug, fludarabine phosphate and suppresses the growth of bladder tumor xenografts. Cancer Gene Therapy. 14: 279-86. PMID 17218950 DOI: 10.1038/Sj.Cgt.7701013  0.79
2007 Sakoda T, Kasahara N, Kedes L, Ohyanagi M. Lentiviral vector-mediated gene transfer to endotherial cells compared with adenoviral and retroviral vectors. Preparative Biochemistry & Biotechnology. 37: 1-11. PMID 17134978 DOI: 10.1080/10826060601039345  0.429
2007 Farzaneh L, Kasahara N, Farzaneh F. The strange case of TGN1412 Cancer Immunology, Immunotherapy. 56: 129-134. PMID 16783575 DOI: 10.1007/S00262-006-0189-8  0.308
2007 Haga K, Lemp NA, Logg CR, Nagashima J, Faure-Kumar E, Gomez GG, Mendez R, Stripecke R, Kruse CA, Cicciarelli JC, Kasahara N. 1911: HLA Class I Silencing by Lentiviral Vector-Mediated Shrna Delivery Averts Cytotoxicity by Alloreactive T Lymphocytes Journal of Urology. 177: 634-635. DOI: 10.1016/S0022-5347(18)32084-6  0.696
2006 Haga K, Lemp NA, Logg CR, Nagashima J, Faure-Kumar E, Gomez GG, Kruse CA, Mendez R, Stripecke R, Kasahara N, Kasahara NA, Cicciarelli JC. Permanent, lowered HLA class I expression using lentivirus vectors with shRNA constructs: Averting cytotoxicity by alloreactive T lymphocytes. Transplantation Proceedings. 38: 3184-8. PMID 17175217 DOI: 10.1016/j.transproceed.2006.10.158  0.701
2006 Hiraoka K, Kimura T, Logg CR, Kasahara N. Tumor-selective gene expression in a hepatic metastasis model after locoregional delivery of a replication-competent retrovirus vector. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 12: 7108-16. PMID 17145835 DOI: 10.1158/1078-0432.Ccr-06-1452  0.785
2006 Guinn BA, Norris JS, Huang L, Farzaneh F, Kasahara N, Deisseroth AB. International Society for Cell and Gene Therapy of Cancer (ISCGT) annual meeting: conference overview and introduction to the symposium papers. Cancer Immunology, Immunotherapy : Cii. 55: 1406-11. PMID 16783577 DOI: 10.1007/S00262-006-0187-X  0.426
2006 Oshikiri T, Miyamoto M, Hiraoka K, Shichinohe T, Kawarada Y, Kato K, Suzuoki M, Nakakubo Y, Kondo S, Dosaka-Akita H, Kasahara N, Katoh H. Transcriptional targeting of adenovirus vectors with the squamous cell carcinoma-specific antigen-2 promoter for selective apoptosis induction in lung cancer. Cancer Gene Therapy. 13: 856-63. PMID 16710347 DOI: 10.1038/Sj.Cgt.7700953  0.351
2006 Wang W, Tai CK, Kershaw AD, Solly SK, Klatzmann D, Kasahara N, Chen TC. Use of replication-competent retroviral vectors in an immunocompetent intracranial glioma model. Neurosurgical Focus. 20: E25. PMID 16709031 DOI: 10.3171/Foc.2006.20.4.1  0.652
2006 Kubo S, Seleme MC, Soifer HS, Perez JL, Moran JV, Kazazian HH, Kasahara N. L1 retrotransposition in nondividing and primary human somatic cells. Proceedings of the National Academy of Sciences of the United States of America. 103: 8036-41. PMID 16698926 DOI: 10.1073/Pnas.0601954103  0.709
2006 Kimura T, Hejing W, Koya R, Faure-Kumar E, Prins R, Comin-Anduix B, Cui Y, Kasahara N, Stripecke R. 993. Optical Bioluminescence and Immunologic Analyses of Lentiviral Vectors Administered In Vivo: Transcriptional Targeting through an MHCII Promoter Yields Persistent Transgene Expression and Lack of CTL Stimulation in Immunocompetent Mice Indicating Tolerance Molecular Therapy. 13. DOI: 10.1016/J.Ymthe.2006.08.1086  0.425
2005 Dalba C, Klatzmann D, Logg CR, Kasahara N. Beyond oncolytic virotherapy: replication-competent retrovirus vectors for selective and stable transduction of tumors. Current Gene Therapy. 5: 655-67. PMID 16457654 DOI: 10.2174/156652305774964659  0.797
2005 Wang W, Zhu NL, Chua J, Swenson S, Costa FK, Schmitmeier S, Sosnowski BA, Shichinohe T, Kasahara N, Chen TC. Retargeting of adenoviral vector using basic fibroblast growth factor ligand for malignant glioma gene therapy. Journal of Neurosurgery. 103: 1058-66. PMID 16381193 DOI: 10.3171/Jns.2005.103.6.1058  0.435
2005 Tai CK, Wang WJ, Chen TC, Kasahara N. Single-shot, multicycle suicide gene therapy by replication-competent retrovirus vectors achieves long-term survival benefit in experimental glioma. Molecular Therapy : the Journal of the American Society of Gene Therapy. 12: 842-51. PMID 16257382 DOI: 10.1016/J.Ymthe.2005.03.017  0.737
2005 Kikuchi E, Menendez S, Ozu C, Ohori M, Cordon-Cardo C, Logg CR, Kasahara N, Bochner BH. 783: Suppression of Bladder Cancer Growth by a Replication-Competent Retroviral Transfer of Escherichia Coli Purine Nucleoside Phosphorylase and Fludarabine Phosphate in Nude Mice Journal of Urology. 173: 212-212. DOI: 10.1016/S0022-5347(18)34952-8  0.698
2005 Kubo S, Soifer HS, Seleme MdC, Moran JV, Kazazian HH, Kasahara N. 1093. An Adenovirus-Retrotransposon Hybrid Vector Achieves Stable Transformation of Quiescent and Primary Human Somatic Cells Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.640  0.764
2005 Hiraoka K, Kimura T, Logg C, Kondo S, Kasahara N. 834. Highly Efficient and Tumor-Selective Gene Delivery in Metastatic Colon Cancer Models Using a Replication-Competent Retrovirus Vector Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.377  0.736
2005 Ozu C, Kikuchi E, Menendez S, Cardo CC, Logg CR, Kasahara N, Bochner BH. 710. Tissue-Specific Gene Therapy by Replication-Competent Retroviral Vector for Prostate Cancer with Fludarabine Phosphate Molecular Therapy. 11. DOI: 10.1016/J.Ymthe.2005.07.250  0.751
2004 Soifer HS, Kasahara N. Retrotransposon-adenovirus hybrid vectors: efficient delivery and stable integration of transgenes via a two-stage mechanism. Current Gene Therapy. 4: 373-84. PMID 15578988 DOI: 10.2174/1566523043346084  0.752
2004 Nakamura S, Nakamura R, Shibata K, Kobayashi M, Sahara N, Shigeno K, Shinjo K, Naito K, Ohnishi K, Kasahara N, Iwaki Y. Development of packaging cell lines for generation of adeno-associated virus vectors by lentiviral gene transfer of trans-complementary components. European Journal of Haematology. 73: 285-94. PMID 15347316 DOI: 10.1111/J.1600-0609.2004.00290.X  0.439
2004 Woodley DT, Keene DR, Atha T, Huang Y, Ram R, Kasahara N, Chen M. Intradermal injection of lentiviral vectors corrects regenerated human dystrophic epidermolysis bullosa skin tissue in vivo. Molecular Therapy : the Journal of the American Society of Gene Therapy. 10: 318-26. PMID 15294178 DOI: 10.1016/J.Ymthe.2004.05.016  0.395
2004 Qiao R, Zhou B, Harboe-Schmidt E, Kasahara N, Kim KJ, Liebler JM, Crandall ED, Borok Z. Subunit-specific coordinate upregulation of sodium pump activity in alveolar epithelial cells by lentivirus-mediated gene transfer. Human Gene Therapy. 15: 457-68. PMID 15144576 DOI: 10.1089/10430340460745784  0.304
2004 Kikuchi E, Menendez S, Ohori M, Cordon-Cardo C, Kasahara N, Bochner BH. Inhibition of orthotopic human bladder tumor growth by lentiviral gene transfer of endostatin. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 1835-42. PMID 15014038 DOI: 10.1158/1078-0432.Ccr-03-0099  0.393
2004 Logg CR, Kasahara N. Retrovirus-mediated gene transfer to tumors: utilizing the replicative power of viruses to achieve highly efficient tumor transduction in vivo. Methods in Molecular Biology (Clifton, N.J.). 246: 499-525. PMID 14970613 DOI: 10.1385/1-59259-650-9:499  0.792
2004 Kikuchi E, Menendez S, Ohori M, Cardon-Carda C, Logg CR, Kasahara N, Bochner BH. 962: Highly Efficient Therapeutic Gene Delivery for Bladder Cancers by Intravesically Administered Replication-Competent Retroviral Vectors Journal of Urology. 171: 255-255. DOI: 10.1016/S0022-5347(18)38199-0  0.76
2004 Hauschulz K, Seefried S, Schenk A, Smirnow I, Wybranietz W, Kasahara N, Bitzer M, Lauer UM. 742. Generation and Evaluation of a New Replication-Competent Retrovirus (RCR) Vector Coding for the SuperCD Suicide Gene Molecular Therapy. 9. DOI: 10.1016/J.Ymthe.2004.06.704  0.555
2003 Stripecke R, Koya RC, Ta HQ, Kasahara N, Levine AM. The use of lentiviral vectors in gene therapy of leukemia: combinatorial gene delivery of immunomodulators into leukemia cells by state-of-the-art vectors. Blood Cells, Molecules & Diseases. 31: 28-37. PMID 12850480 DOI: 10.1016/S1079-9796(03)00062-7  0.358
2003 Tai CK, Logg CR, Park JM, Anderson WF, Press MF, Kasahara N. Antibody-mediated targeting of replication-competent retroviral vectors. Human Gene Therapy. 14: 789-802. PMID 12804141 DOI: 10.1089/104303403765255174  0.802
2003 Chen M, Li W, Fan J, Kasahara N, Woodley D. An efficient gene transduction system for studying gene function in primary human dermal fibroblasts and epidermal keratinocytes Clinical and Experimental Dermatology. 28: 193-199. PMID 12653712 DOI: 10.1046/J.1365-2230.2003.01191.X  0.444
2003 Wang WJ, Tai CK, Kasahara N, Chen TC. Highly efficient and tumor-restricted gene transfer to malignant gliomas by replication-competent retroviral vectors. Human Gene Therapy. 14: 117-27. PMID 12614563 DOI: 10.1089/104303403321070810  0.719
2003 Sakoda T, Kasahara N, Kedes L. Lentivirus vector-mediated gene transfer to cardiomyocytes. Methods in Molecular Biology (Clifton, N.J.). 219: 53-70. PMID 12596998 DOI: 10.1385/1-59259-350-X:53  0.416
2002 Logg CR, Logg A, Matusik RJ, Bochner BH, Kasahara N. Tissue-specific transcriptional targeting of a replication-competent retroviral vector. Journal of Virology. 76: 12783-91. PMID 12438603 DOI: 10.1128/Jvi.76.24.12783-12791.2002  0.789
2002 Chen M, Kasahara N, Keene DR, Chan L, Hoeffler WK, Finlay D, Barcova M, Cannon PM, Mazurek C, Woodley DT. Restoration of type VII collagen expression and function in dystrophic epidermolysis bullosa. Nature Genetics. 32: 670-5. PMID 12426566 DOI: 10.1038/Ng1041  0.402
2002 Koya RC, Kasahara N, Pullarkat V, Levine AM, Stripecke R. Transduction of acute myeloid leukemia cells with third generation self-inactivating lentiviral vectors expressing CD80 and GM-CSF: Effects on proliferation, differentiation, and stimulation of allogeneic and autologous anti-leukemia immune responses Leukemia. 16: 1645-1654. PMID 12200676 DOI: 10.1038/Sj.Leu.2402582  0.397
2002 Hiraoka K, Hida Y, Miyamoto M, Oshikiri T, Suzuoki M, Nakakubo Y, Shinohara T, Itoh T, Shichinohe T, Kondo S, Kasahara N, Katoh H. High expression of tumor-associated antigen RCAS1 in pancreatic ductal adenocarcinoma is an unfavorable prognostic marker. International Journal of Cancer. Journal International Du Cancer. 99: 418-23. PMID 11992411 DOI: 10.1002/Ijc.10381  0.369
2002 Soifer H, Higo C, Logg CR, Jih LJ, Shichinohe T, Harboe-Schmidt E, Mitani K, Kasahara N. A novel, helper-dependent, adenovirus-retrovirus hybrid vector: stable transduction by a two-stage mechanism. Molecular Therapy : the Journal of the American Society of Gene Therapy. 5: 599-608. PMID 11991751 DOI: 10.1006/Mthe.2002.0586  0.823
2002 Soiefer H, Higo C, Logg CR, Jih LJL, Shichinohe T, Harboe-Schmidt E, Mitani K, Kasahara N. A Novel, Helper-Dependent, Adenovirus–Retrovirus Hybrid Vector: Stable Transduction by a Two-Stage Mechanism: MOLECULAR THERAPY 5: 599–608 (2002). doi:10.1006/mthe.2001.0586 Molecular Therapy. 6. DOI: 10.1006/Mthe.2002.0641  0.7
2001 Yoon TKL, Shichinohe T, Laquerre S, Kasahara N. Selectively replicating adenoviruses for oncolytic therapy Current Cancer Drug Targets. 1: 85-107. PMID 12188883 DOI: 10.2174/1568009013334223  0.52
2001 Medina-Kauwe LK, Maguire M, Kasahara N, Kedes L. Nonviral gene delivery to human breast cancer cells by targeted Ad5 penton proteins. Gene Therapy. 8: 1753-61. PMID 11803394 DOI: 10.1038/Sj.Gt.3301583  0.385
2001 Shichinohe T, Bochner BH, Mizutani K, Nishida M, Hegerich-Gilliam S, Naldini L, Kasahara N. Development of lentiviral vectors for antiangiogenic gene delivery Cancer Gene Therapy. 8: 879-889. PMID 11773978 DOI: 10.1038/Sj.Cgt.7700388  0.529
2001 Weber E, French Anderson W, Kasahara N. Recent advances in retrovirus vector-mediated gene therapy: Teaching an old vector new tricks Current Opinion in Molecular Therapeutics. 3: 439-453. PMID 11699888  0.334
2001 Borok Z, Harboe-Schmidt JE, Brody SL, You Y, Zhou B, Li X, Cannon PM, Kim KJ, Crandall ED, Kasahara N. Vesicular stomatitis virus G-pseudotyped lentivirus vectors mediate efficient apical transduction of polarized quiescent primary alveolar epithelial cells. Journal of Virology. 75: 11747-54. PMID 11689655 DOI: 10.1128/Jvi.75.23.11747-11754.2001  0.466
2001 Chang Z, Pan J, Logg C, Kasahara N, Roy-Burman P. A replication-competent feline leukemia virus, subgroup A (FeLV-A), tagged with green fluorescent protein reporter exhibits in vitro biological properties similar to those of the parental FeLV-A. Journal of Virology. 75: 8837-41. PMID 11507228 DOI: 10.1128/Jvi.75.18.8837-8841.2001  0.755
2001 Soifer H, Higo C, Kazazian JH, Moran JV, Mitani K, Kasahara N. Stable integration of transgenes delivered by a retrotransposon-adenovirus hybrid vector Human Gene Therapy. 12: 1417-1428. PMID 11485633 DOI: 10.1089/104303401750298571  0.754
2001 Logg CR, Logg A, Tai CK, Cannon PM, Kasahara N. Genomic stability of murine leukemia viruses containing insertions at the Env-3' untranslated region boundary. Journal of Virology. 75: 6989-98. PMID 11435579 DOI: 10.1128/Jvi.75.15.6989-6998.2001  0.773
2001 Medina-Kauwe LK, Kasahara N, Kedes L. 3PO, a novel nonviral gene delivery system using engineered Ad5 penton proteins Gene Therapy. 8: 795-803. PMID 11420644 DOI: 10.1038/Sj.Gt.3301448  0.382
2001 Logg CR, Tai CK, Logg A, Anderson WF, Kasahara N. A uniquely stable replication-competent retrovirus vector achieves efficient gene delivery in vitro and in solid tumors. Human Gene Therapy. 12: 921-32. PMID 11387057 DOI: 10.1089/104303401750195881  0.833
2000 Smith E, Redman RA, Logg CR, Coetzee GA, Kasahara N, Frenkel B. Glucocorticoids inhibit developmental stage-specific osteoblast cell cycle. Dissociation of cyclin A-cyclin-dependent kinase 2 from E2F4-p130 complexes. The Journal of Biological Chemistry. 275: 19992-20001. PMID 10867026 DOI: 10.1074/Jbc.M001758200  0.66
1999 Sakoda T, Kasahara N, Hamamori Y, Kedes L. A high-titer lentiviral production system mediates efficient transduction of differentiated cells including beating cardiac myocytes Journal of Molecular and Cellular Cardiology. 31: 2037-2047. PMID 10591030 DOI: 10.1006/Jmcc.1999.1035  0.432
1995 Takahashi T, Shirasawa T, Miyake K, Yahagi Y, Maruyama N, Kasahara N, Kawamura T, Matsumura O, Mitarai T, Sakai O. Protein Tyrosine Kinases Expressed in Glomeruli and Cultured Glomerular Cells: Flt-1 and VEGF Expression in Renal Mesangial Cells Biochemical and Biophysical Research Communications. 209: 218-226. PMID 7726838 DOI: 10.1006/Bbrc.1995.1492  0.312
1995 Han X, Kasahara N, Kan YW. Ligand-directed retroviral targeting of human breast cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 92: 9747-51. PMID 7568210 DOI: 10.1073/Pnas.92.21.9747  0.371
1995 Kasahara N, Dozy AM, Kan YW. Tissue-specific targeting of retroviral vectors via ligand-receptor interactions Advanced Drug Delivery Reviews. 17: 227-234. DOI: 10.1016/0169-409X(95)00055-C  0.423
1994 Kasahara N, Dozy AM, Kan YW. Tissue-specific targeting of retroviral vectors through ligand-receptor interactions. Science (New York, N.Y.). 266: 1373-6. PMID 7973726 DOI: 10.1126/Science.7973726  0.423
1993 Sakamoto S, Mizuno M, Kudo H, Suzuki S, Kasahara N, Sugiura Y, Mori T, Nagasawa H. Suppression of mammary tumors by oral administration of 1-(2- tetrahydrofuryl)-5-fluorouracil in combination with uracil in SHN virgin mice Anti-Cancer Drugs. 4: 651-655. PMID 8298164 DOI: 10.1097/00001813-199312000-00007  0.314
1992 Sakamoto S, Kasahara N, Kudo H, Iwama T. Effects of carcinogenesis on colonic thymidine kinase activity in familial adenomatous polyposis Carcinogenesis. 13: 873-876. PMID 1316815 DOI: 10.1093/Carcin/13.5.873  0.304
Show low-probability matches.