| Year |
Citation |
Score |
| 2023 |
Pallan PS, Lybrand TP, Rozners E, Abramov M, Schepers G, Eremeeva E, Herdewijn P, Egli M. Conformational Morphing by a DNA Analogue Featuring 7-Deazapurines and 5-Halogenpyrimidines and the Origins of Adenine-Tract Geometry. Biochemistry. PMID 37694722 DOI: 10.1021/acs.biochem.3c00327 |
0.354 |
|
| 2023 |
Matsuda S, Bala S, Liao JY, Datta D, Mikami A, Woods L, Harp JM, Gilbert JA, Bisbe A, Manoharan RM, Kim M, Theile CS, Guenther DC, Jiang Y, Agarwal S, ... ... Egli M, et al. Shorter Is Better: The α-(l)-Threofuranosyl Nucleic Acid Modification Improves Stability, Potency, Safety, and Ago2 Binding and Mitigates Off-Target Effects of Small Interfering RNAs. Journal of the American Chemical Society. PMID 37638886 DOI: 10.1021/jacs.3c04744 |
0.32 |
|
| 2023 |
Richie-Jannetta R, Pallan P, Kingsley PJ, Kamdar N, Egli M, Marnett LJ. The peroxidation-derived DNA adduct, 6-oxo-MdG, is a strong block to replication by human DNA polymerase η. The Journal of Biological Chemistry. 105067. PMID 37468099 DOI: 10.1016/j.jbc.2023.105067 |
0.354 |
|
| 2023 |
Ghosh A, Akabane-Nakata M, Kundu J, Harp JM, Madaoui M, Egli M, Manoharan M, Sinha S. Synthesis and Biophysical Properties of Phosphorodiamidate Piperidino Oligomers. Organic Letters. PMID 36734846 DOI: 10.1021/acs.orglett.2c04067 |
0.305 |
|
| 2023 |
Egli M, Schlegel MK, Manoharan M. Acyclic (S)-Glycol Nucleic Acid (S-GNA) Modification of siRNAs Improves the Safety of RNAi Therapeutics While Maintaining Potency. Rna (New York, N.Y.). PMID 36725319 DOI: 10.1261/rna.079526.122 |
0.31 |
|
| 2022 |
Kellum AH, Pallan PS, Nilforoushan A, Sturla SJ, Stone MP, Egli M. Conformation and Pairing Properties of an -Methyl-2'-deoxyguanosine-Directed Benzimidazole Nucleoside Analog in Duplex DNA. Chemical Research in Toxicology. PMID 35973057 DOI: 10.1021/acs.chemrestox.2c00165 |
0.375 |
|
| 2022 |
Harp JM, Lybrand TP, Pallan PS, Coates L, Sullivan B, Egli M. Cryo neutron crystallography demonstrates influence of RNA 2'-OH orientation on conformation, sugar pucker and water structure. Nucleic Acids Research. 50: 7721-7738. PMID 35819202 DOI: 10.1093/nar/gkac577 |
0.336 |
|
| 2022 |
Egli M, Zhang S. Ned Seeman and the prediction of amino acid-basepair motifs mediating protein-nucleic acid recognition. Biophysical Journal. PMID 35711143 DOI: 10.1016/j.bpj.2022.06.017 |
0.3 |
|
| 2020 |
Pallan PS, Lybrand TP, Schlegel MK, Harp JM, Jahns H, Manoharan M, Egli M. Incorporating a Thiophosphate Modification into a Common RNA Tetraloop Motif Causes an Unanticipated Stability Boost. Biochemistry. PMID 33275419 DOI: 10.1021/acs.biochem.0c00685 |
0.31 |
|
| 2020 |
Richert C, Jovanovic D, Tremmel P, Pallan SP, Egli M. The Enzyme-Free Release of Nucleotides from Phosphoramidates Depends Strongly on the Amino Acid. Angewandte Chemie (International Ed. in English). PMID 32757352 DOI: 10.1002/Ange.202008665 |
0.327 |
|
| 2020 |
Kumar P, Degaonkar R, Guenther DC, Abramov M, Schepers G, Capobianco M, Jiang Y, Harp J, Kaittanis C, Janas MM, Castoreno A, Zlatev I, Schlegel MK, Herdewijn P, Egli M, et al. Chimeric siRNAs with chemically modified pentofuranose and hexopyranose nucleotides: altritol-nucleotide (ANA) containing GalNAc-siRNA conjugates: in vitro and in vivo RNAi activity and resistance to 5'-exonuclease. Nucleic Acids Research. PMID 32170309 DOI: 10.1093/Nar/Gkaa125 |
0.38 |
|
| 2019 |
Minko IG, Vartanian VL, Tozaki NN, Coskun E, Coskun SH, Jaruga P, Yeo J, David SS, Stone MP, Egli M, Dizdaroglu M, McCullough AK, Lloyd RS. Recognition of DNA adducts by edited and unedited forms of DNA glycosylase NEIL1. Dna Repair. 85: 102741. PMID 31733589 DOI: 10.1016/J.Dnarep.2019.102741 |
0.41 |
|
| 2019 |
Minko IG, Vartanian VL, Tozaki NN, Linde OK, Jaruga P, Coskun SH, Coskun E, Qu C, He H, Xu C, Chen T, Song Q, Jiao Y, Stone MP, Egli M, et al. Characterization of rare NEIL1 variants found in East Asian populations. Dna Repair. 79: 32-39. PMID 31100703 DOI: 10.1016/J.Dnarep.2019.05.001 |
0.301 |
|
| 2019 |
Kumar P, Parmar RG, Brown CR, Willoughby JLS, Foster DJ, Babu IR, Schofield S, Jadhav V, Charisse K, Nair JK, Rajeev KG, Maier MA, Egli M, Manoharan M. 5'-Morpholino modification of the sense strand of an siRNA makes it a more effective passenger. Chemical Communications (Cambridge, England). PMID 30977478 DOI: 10.1039/C9Cc00977A |
0.38 |
|
| 2019 |
Egli M, Manoharan M. Re-Engineering RNA Molecules into Therapeutic Agents. Accounts of Chemical Research. PMID 30912917 DOI: 10.1021/Acs.Accounts.8B00650 |
0.428 |
|
| 2019 |
Akabane-Nakata M, Kumar P, Das RS, Erande ND, Matsuda S, Egli M, Manoharan M. Synthesis and Biophysical Characterization of RNAs Containing 2'-Fluorinated Northern Methanocarbacyclic Nucleotides. Organic Letters. PMID 30892051 DOI: 10.1021/Acs.Orglett.8B04153 |
0.317 |
|
| 2019 |
Su Y, Ghodke PP, Egli M, Li L, Wang Y, Guengerich FP. Human DNA polymerase has reverse transcriptase activity in cellular environments. The Journal of Biological Chemistry. PMID 30842261 DOI: 10.1074/Jbc.Ra119.007925 |
0.457 |
|
| 2019 |
Egli M, Lybrand TP. Enhanced Dispersion and Polarization Interactions Achieved through Dithiophosphate Group Incorporation Yield a Dramatic Binding Affinity Increase for an RNA Aptamer-Thrombin Complex. Journal of the American Chemical Society. PMID 30794399 DOI: 10.1021/Jacs.9B00104 |
0.364 |
|
| 2019 |
Sheehan JH, Smith JA, Pallan PS, Lybrand TP, Egli M. Molecular Dynamics Simulation of Homo-DNA: The Role of Crystal Packing in Duplex Conformation Crystals. 9: 532. DOI: 10.3390/cryst9100532 |
0.392 |
|
| 2018 |
Seo M, Lei L, Egli M. Label-Free Electrophoretic Mobility Shift Assay (EMSA) for Measuring Dissociation Constants of Protein-RNA Complexes. Current Protocols in Nucleic Acid Chemistry. e70. PMID 30461222 DOI: 10.1002/Cpnc.70 |
0.33 |
|
| 2018 |
Harp JM, Coates L, Sullivan B, Egli M. Cryo-neutron crystallographic data collection and preliminary refinement of left-handed Z-DNA d(CGCGCG). Acta Crystallographica. Section F, Structural Biology Communications. 74: 603-609. PMID 30279310 DOI: 10.1107/S2053230X1801066X |
0.403 |
|
| 2018 |
Harp JM, Guenther DC, Bisbe A, Perkins L, Matsuda S, Bommineni GR, Zlatev I, Foster DJ, Taneja N, Charisse K, Maier MA, Rajeev KG, Manoharan M, Egli M. Structural basis for the synergy of 4'- and 2'-modifications on siRNA nuclease resistance, thermal stability and RNAi activity. Nucleic Acids Research. PMID 30107495 DOI: 10.1093/nar/gky703 |
0.319 |
|
| 2018 |
Dolot R, Lam CH, Sierant M, Zhao Q, Liu FW, Nawrot B, Egli M, Yang X. Crystal structures of thrombin in complex with chemically modified thrombin DNA aptamers reveal the origins of enhanced affinity. Nucleic Acids Research. PMID 29684204 DOI: 10.1093/Nar/Gky268 |
0.357 |
|
| 2018 |
Parmar RG, Brown CR, Matsuda S, Willoughby JLS, Theile CS, Charissé K, Foster DJ, Zlatev I, Jadhav V, Maier MA, Egli M, Manoharan M, Rajeev KG. Facile Synthesis, Geometry, and 2'-Substituent-Dependent in Vivo Activity of 5'-(E)- and 5'-(Z)-Vinylphosphonate-Modified siRNA Conjugates. Journal of Medicinal Chemistry. PMID 29376650 DOI: 10.1021/Acs.Jmedchem.7B01147 |
0.345 |
|
| 2018 |
Hardcastle T, Novosjolova I, Kotikam V, Cheruiyot SK, Mutisya D, Kennedy SD, Egli M, Kelley ML, Smith AVB, Rozners E. A Single Amide Linkage in the Passenger Strand Suppresses Its Activity and Enhances Guide Strand Targeting of siRNAs. Acs Chemical Biology. PMID 29298376 DOI: 10.1021/Acschembio.7B01012 |
0.383 |
|
| 2017 |
Su Y, Egli M, Guengerich FP. Human DNA polymerase η accommodates RNA for strand extension. The Journal of Biological Chemistry. PMID 28972162 DOI: 10.1074/Jbc.M117.809723 |
0.446 |
|
| 2017 |
Malek-Adamian E, Guenther D, Matsuda S, Martínez-Montero S, Zlatev I, Harp J, Burai Patrascu M, Foster DJ, Fakhoury JJ, Perkins L, Moitessier N, Manoharan R, Taneja N, Bisbe A, Charisse K, ... ... Egli M, et al. 4'-C-Methoxy-2'-Deoxy-2'-Fluoro Modified Ribonucleotides Improve Metabolic Stability and Elicit Efficient RNAi-Mediated Gene Silencing. Journal of the American Chemical Society. PMID 28937776 DOI: 10.1021/Jacs.7B07582 |
0.323 |
|
| 2017 |
Yang X, Dinuka Abeydeera N, Liu FW, Egli M. Origins of the enhanced affinity of RNA-protein interactions triggered by RNA phosphorodithioate backbone modification. Chemical Communications (Cambridge, England). PMID 28868553 DOI: 10.1039/C7Cc05722A |
0.353 |
|
| 2017 |
Mutisya D, Hardcastle T, Cheruiyot SK, Pallan PS, Kennedy SD, Egli M, Kelley ML, Smith AVB, Rozners E. Amide linkages mimic phosphates in RNA interactions with proteins and are well tolerated in the guide strand of short interfering RNAs. Nucleic Acids Research. 45: 8142-8155. PMID 28854734 DOI: 10.1093/Nar/Gkx558 |
0.429 |
|
| 2017 |
Peters JP, Kowal EA, Pallan PS, Egli M, Maher LJ. Comparative analysis of inosine-substituted duplex DNA by circular dichroism and X-ray crystallography. Journal of Biomolecular Structure & Dynamics. 1-60. PMID 28818035 DOI: 10.1080/07391102.2017.1369164 |
0.477 |
|
| 2017 |
Schlegel MK, Foster DJ, Kel'in AV, Zlatev I, Bisbe A, Jayaraman M, Lackey JG, Rajeev KG, Charisse K, Harp J, Pallan PS, Maier MA, Egli M, Manoharan M. Chirality Dependent Potency Enhancement and Structural Impact of Glycol Nucleic Acid Modification on siRNA. Journal of the American Chemical Society. PMID 28570818 DOI: 10.1021/Jacs.7B02694 |
0.456 |
|
| 2016 |
Lou X, Egli M, Yang X. Determining Functional Aptamer-Protein Interaction by Biolayer Interferometry. Current Protocols in Nucleic Acid Chemistry. 67: 7.25.1-7.25.15. PMID 27911494 DOI: 10.1002/Cpnc.18 |
0.369 |
|
| 2016 |
Xu W, Kool D, O'Flaherty DK, Keating A, Sacre L, Egli M, Noronha AM, Wilds CJ, Zhao L. O6-2'-Deoxyguanosine-butylene-O6-2'-deoxyguanosine DNA Interstrand Cross-Links are Replication-Blocking and Mutagenic DNA Lesions. Chemical Research in Toxicology. PMID 27768841 DOI: 10.1021/Acs.Chemrestox.6B00278 |
0.392 |
|
| 2016 |
Patra A, Zhang Q, Guengerich FP, Egli M. Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase η. The Journal of Biological Chemistry. 291: 24304-24313. PMID 27694439 DOI: 10.1074/Jbc.M116.755462 |
0.429 |
|
| 2016 |
Pallan PS, Prakash TP, De Leon AR, Egli M. Limits of RNA 2'-OH Mimicry by Fluorine: Crystal Structure of Bacillus halodurans RNase H Bound to a 2'F-RNA:DNA Hybrid. Biochemistry. PMID 27611889 DOI: 10.1021/Acs.Biochem.6B00849 |
0.479 |
|
| 2016 |
O'Flaherty DK, Patra A, Su Y, Guengerich FP, Egli M, Wilds CJ. Lesion Orientation of O (4)-Alkylthymidine Influences Replication by Human DNA Polymerase η. Chemical Science. 7: 4896-4904. PMID 27574558 DOI: 10.1039/C6Sc00666C |
0.371 |
|
| 2016 |
Abeydeera ND, Egli M, Cox N, Mercier K, Conde JN, Pallan PS, Mizurini DM, Sierant M, Hibti FE, Hassell T, Wang T, Liu FW, Liu HM, Martinez C, Sood AK, et al. Evoking picomolar binding in RNA by a single phosphorodithioate linkage. Nucleic Acids Research. PMID 27566147 DOI: 10.1093/Nar/Gkw725 |
0.387 |
|
| 2016 |
Patra A, Politica DA, Chatterjee A, Tokarsky EJ, Suo Z, Basu A, Stone MP, Egli M. Mechanism of Error-Free Bypass of the Environmental Carcinogen N-(2-Deoxyguanosin-8-yl)-3-aminobenzanthrone Adduct by Human DNA Polymerase. Chembiochem : a European Journal of Chemical Biology. PMID 27556902 DOI: 10.1002/Cbic.201600420 |
0.44 |
|
| 2016 |
Choi JY, Patra A, Yeom M, Lee YS, Zhang Q, Egli M, Guengerich FP. Kinetic and Structural Impact of Metal Ions and Genetic Variations on Human DNA Polymerase ι. The Journal of Biological Chemistry. PMID 27555320 DOI: 10.1074/Jbc.M116.748285 |
0.374 |
|
| 2016 |
Anosova I, Kowal EA, Sisco NJ, Sau S, Liao JY, Bala S, Rozners E, Egli M, Chaput JC, Van Horn WD. Structural Insights into Conformational Differences between DNA/TNA and RNA/TNA Chimeric Duplexes. Chembiochem : a European Journal of Chemical Biology. PMID 27347671 DOI: 10.1002/Cbic.201600349 |
0.478 |
|
| 2016 |
Patra A, Su Y, Zhang Q, Johnson KM, Guengerich FP, Egli M. Structural and Kinetic Analysis of Miscoding Opposite the DNA Adduct 1,N6-Ethenodeoxyadenosine by Human Translesion DNA Polymerase η. The Journal of Biological Chemistry. PMID 27226627 DOI: 10.1074/Jbc.M116.732487 |
0.432 |
|
| 2016 |
Kel In AV, Zlatev I, Harp J, Jayaraman M, Bisbe A, O Shea J, Taneja N, Manoharan RM, Khan S, Charisse K, Maier MA, Egli M, Rajeev KG, Manoharan M. Structural Basis of Duplex Thermodynamic Stability and Enhanced Nuclease Resistance of 5'-C-Methyl Pyrimidine-Modified Oligonucleotides. The Journal of Organic Chemistry. PMID 26940174 DOI: 10.1021/Acs.Joc.5B02375 |
0.344 |
|
| 2016 |
Su Y, Egli M, Guengerich FP. Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase η. The Journal of Biological Chemistry. PMID 26740629 DOI: 10.1074/Jbc.M115.706226 |
0.472 |
|
| 2016 |
Egli M, Pallan PS. Generating Crystallographic Models of DNA Dodecamers from Structures of RNase H:DNA Complexes. Methods in Molecular Biology (Clifton, N.J.). 1320: 111-26. PMID 26227040 DOI: 10.1007/978-1-4939-2763-0_8 |
0.489 |
|
| 2016 |
Patra A, Politica DA, Stone MP, Egli M. Transletion Polymerase Synthesis across C8-Guanine Adduct of the Environmental Carcinogen 3-Nitrobenzanthrone by Human DNA Polymerase Eta Chembiochem. DOI: 10.2210/Pdb5Jum/Pdb |
0.388 |
|
| 2016 |
Anosova I, Kowal EA, Sisco NJ, Sau S, Liao J, Bala S, Rozners E, Egli M, Chaput JC, Van Horn WD. Back Cover: Structural Insights into Conformation Differences between DNA/TNA and RNA/TNA Chimeric Duplexes (ChemBioChem 18/2016) Chembiochem. 17: 1785-1785. DOI: 10.1002/Cbic.201600460 |
0.474 |
|
| 2015 |
Zlatev I, Foster DJ, Liu J, Charisse K, Brigham B, Parmar RG, Jadhav V, Maier MA, Rajeev KG, Egli M, Manoharan M. 5'-C-Malonyl RNA: small interfering RNAs modified with 5'-monophosphate bioisostere demonstrate gene silencing activity. Acs Chemical Biology. PMID 26675211 DOI: 10.1021/Acschembio.5B00654 |
0.347 |
|
| 2015 |
Anosova I, Kowal EA, Dunn MR, Chaput JC, Van Horn WD, Egli M. The structural diversity of artificial genetic polymers. Nucleic Acids Research. PMID 26673703 DOI: 10.1093/Nar/Gkv1472 |
0.32 |
|
| 2015 |
O'Flaherty DK, Guengerich FP, Egli M, Wilds CJ. Backbone Flexibility Influences Nucleotide Incorporation by Human Translesion DNA Polymerase η opposite Intrastrand Cross-Linked DNA. Biochemistry. 54: 7449-56. PMID 26624500 DOI: 10.1021/Acs.Biochem.5B01078 |
0.427 |
|
| 2015 |
Pattanayek R, Egli M. Protein-Protein Interactions in the Cyanobacterial Circadian Clock: Structure of KaiA Dimer in Complex with C-Terminal KaiC Peptides at 2.8 Å Resolution. Biochemistry. 54: 4575-8. PMID 26200123 DOI: 10.1021/Acs.Biochem.5B00694 |
0.343 |
|
| 2015 |
Patra A, Banerjee S, Johnson Salyard TL, Malik CK, Christov PP, Rizzo CJ, Stone MP, Egli M. Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV. Journal of the American Chemical Society. 137: 7011-4. PMID 25988947 DOI: 10.1021/Jacs.5B02701 |
0.428 |
|
| 2015 |
Su Y, Patra A, Harp JM, Egli M, Guengerich FP. Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2'-deoxyguanosine. The Journal of Biological Chemistry. 290: 15921-33. PMID 25947374 DOI: 10.1074/Jbc.M115.653691 |
0.426 |
|
| 2015 |
Pallan PS, Wang C, Lei L, Yoshimoto FK, Auchus RJ, Waterman MR, Guengerich FP, Egli M. Human Cytochrome P450 21A2, the Major Steroid 21-Hydroxylase: STRUCTURE OF THE ENZYME·PROGESTERONE SUBSTRATE COMPLEX AND RATE-LIMITING C-H BOND CLEAVAGE. The Journal of Biological Chemistry. 290: 13128-43. PMID 25855791 DOI: 10.1074/Jbc.M115.646307 |
0.303 |
|
| 2015 |
Patra A, Zhang Q, Lei L, Su Y, Egli M, Guengerich FP. Structural and kinetic analysis of nucleoside triphosphate incorporation opposite an abasic site by human translesion DNA polymerase η. The Journal of Biological Chemistry. 290: 8028-38. PMID 25666608 DOI: 10.1074/Jbc.M115.637561 |
0.396 |
|
| 2015 |
Egli M. Structural and biophysical methods to analyze clock function and mechanism. Methods in Enzymology. 551: 223-66. PMID 25662460 DOI: 10.1016/Bs.Mie.2014.10.004 |
0.323 |
|
| 2015 |
Szulik MW, Pallan PS, Nocek B, Voehler M, Banerjee S, Brooks S, Joachimiak A, Egli M, Eichman BF, Stone MP. Differential stabilities and sequence-dependent base pair opening dynamics of Watson-Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine. Biochemistry. 54: 1294-305. PMID 25632825 DOI: 10.1021/Bi501534X |
0.372 |
|
| 2015 |
Guengerich FP, Zhao L, Pence MG, Egli M. Structure and function of the translesion DNA polymerases and interactions with damaged DNA Perspectives in Science. 4: 24-31. DOI: 10.1016/J.Pisc.2014.12.005 |
0.459 |
|
| 2014 |
Mutisya D, Selvam C, Lunstad BD, Pallan PS, Haas A, Leake D, Egli M, Rozners E. Amides are excellent mimics of phosphate internucleoside linkages and are well tolerated in short interfering RNAs. Nucleic Acids Research. 42: 6542-51. PMID 24813446 DOI: 10.1093/Nar/Gku235 |
0.399 |
|
| 2014 |
Patra A, Nagy LD, Zhang Q, Su Y, Müller L, Guengerich FP, Egli M. Kinetics, structure, and mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine bypass by human DNA polymerase η. The Journal of Biological Chemistry. 289: 16867-82. PMID 24759104 DOI: 10.1074/Jbc.M114.551820 |
0.433 |
|
| 2014 |
Wu SY, Yang X, Gharpure KM, Hatakeyama H, Egli M, McGuire MH, Nagaraja AS, Miyake TM, Rupaimoole R, Pecot CV, Taylor M, Pradeep S, Sierant M, Rodriguez-Aguayo C, Choi HJ, et al. 2'-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity. Nature Communications. 5: 3459. PMID 24619206 DOI: 10.1038/Ncomms4459 |
0.313 |
|
| 2014 |
Pallan PS, Yang X, Sierant M, Abeydeera ND, Hassell T, Martinez C, Janicka M, Nawrot B, Egli M. Crystal structure, stability and Ago2 affinity of phosphorodithioate-modified RNAs Rsc Advances. 4: 64901-64904. DOI: 10.1039/C4Ra10986D |
0.388 |
|
| 2013 |
Shanmugam G, Minko IG, Banerjee S, Christov PP, Kozekov ID, Rizzo CJ, Lloyd RS, Egli M, Stone MP. Ring-opening of the γ-OH-PdG adduct promotes error-free bypass by the Sulfolobus solfataricus DNA polymerase Dpo4. Chemical Research in Toxicology. 26: 1348-60. PMID 23947567 DOI: 10.1021/Tx400200B |
0.434 |
|
| 2013 |
Villarreal SA, Pattanayek R, Williams DR, Mori T, Qin X, Johnson CH, Egli M, Stewart PL. CryoEM and molecular dynamics of the circadian KaiB-KaiC complex indicates that KaiB monomers interact with KaiC and block ATP binding clefts. Journal of Molecular Biology. 425: 3311-24. PMID 23796516 DOI: 10.1016/J.Jmb.2013.06.018 |
0.362 |
|
| 2013 |
Kowal EA, Lad RR, Pallan PS, Dhummakupt E, Wawrzak Z, Egli M, Sturla SJ, Stone MP. Recognition of O6-benzyl-2'-deoxyguanosine by a perimidinone-derived synthetic nucleoside: a DNA interstrand stacking interaction. Nucleic Acids Research. 41: 7566-76. PMID 23748954 DOI: 10.1093/Nar/Gkt488 |
0.362 |
|
| 2013 |
Ketkar A, Zafar MK, Maddukuri L, Yamanaka K, Banerjee S, Egli M, Choi JY, Lloyd RS, Eoff RL. Leukotriene biosynthesis inhibitor MK886 impedes DNA polymerase activity. Chemical Research in Toxicology. 26: 221-32. PMID 23305233 DOI: 10.1021/Tx300392M |
0.402 |
|
| 2013 |
Patra A, Harp J, Pallan PS, Zhao L, Abramov M, Herdewijn P, Egli M. Structure, stability and function of 5-chlorouracil modified A:U and G:U base pairs. Nucleic Acids Research. 41: 2689-97. PMID 23275540 DOI: 10.1093/Nar/Gks1316 |
0.344 |
|
| 2013 |
Seth PP, Pallan PS, Swayze EE, Egli M. Synthesis, duplex stabilization and structural properties of a fluorinated carbocyclic LNA analogue. Chembiochem : a European Journal of Chemical Biology. 14: 58-62. PMID 23193103 DOI: 10.1002/Cbic.201200669 |
0.462 |
|
| 2013 |
Egli M, Minasov G, Tereshko V, Pallan PS, Teplova M, Inamati GB, Lesnik EA, Owens SR, Ross BS, Prakash TP, Manoharan M. Erratum: Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: Comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2′- O -ribonucleic acid modifications (Biochemistry (2005) 44: 25 (9045-9057) DOI: 10.1021/bi050574m) Biochemistry. 52. DOI: 10.1021/Bi4002166 |
0.399 |
|
| 2012 |
Yamanaka K, Dorjsuren D, Eoff RL, Egli M, Maloney DJ, Jadhav A, Simeonov A, Lloyd RS. A comprehensive strategy to discover inhibitors of the translesion synthesis DNA polymerase κ. Plos One. 7: e45032. PMID 23056190 DOI: 10.1371/Journal.Pone.0045032 |
0.411 |
|
| 2012 |
Patra A, Paolillo M, Charisse K, Manoharan M, Rozners E, Egli M. 2'-Fluoro RNA shows increased Watson-Crick H-bonding strength and stacking relative to RNA: evidence from NMR and thermodynamic data. Angewandte Chemie (International Ed. in English). 51: 11863-6. PMID 23055396 DOI: 10.1002/Anie.201204946 |
0.364 |
|
| 2012 |
Ketkar A, Zafar MK, Banerjee S, Marquez VE, Egli M, Eoff RL. Differential furanose selection in the active sites of archaeal DNA polymerases probed by fixed-conformation nucleotide analogues. Biochemistry. 51: 9234-44. PMID 23050956 DOI: 10.1021/Bi301043K |
0.484 |
|
| 2012 |
Pattanayek R, Sidiqi SK, Egli M. Crystal structure of the redox-active cofactor dibromothymoquinone bound to circadian clock protein KaiA and structural basis for dibromothymoquinone's ability to prevent stimulation of KaiC phosphorylation by KaiA. Biochemistry. 51: 8050-2. PMID 23020633 DOI: 10.1021/Bi301222T |
0.311 |
|
| 2012 |
Zhao L, Pence MG, Christov PP, Wawrzak Z, Choi JY, Rizzo CJ, Egli M, Guengerich FP. Basis of miscoding of the DNA adduct N2,3-ethenoguanine by human Y-family DNA polymerases. The Journal of Biological Chemistry. 287: 35516-26. PMID 22910910 DOI: 10.1074/Jbc.M112.403253 |
0.388 |
|
| 2012 |
Ketkar A, Zafar MK, Banerjee S, Marquez VE, Egli M, Eoff RL. A nucleotide-analogue-induced gain of function corrects the error-prone nature of human DNA polymerase iota. Journal of the American Chemical Society. 134: 10698-705. PMID 22632140 DOI: 10.1021/Ja304176Q |
0.457 |
|
| 2012 |
Pallan PS, Allerson CR, Berdeja A, Seth PP, Swayze EE, Prakash TP, Egli M. Structure and nuclease resistance of 2',4'-constrained 2'-O-methoxyethyl (cMOE) and 2'-O-ethyl (cEt) modified DNAs. Chemical Communications (Cambridge, England). 48: 8195-7. PMID 22614180 DOI: 10.1039/C2Cc32286B |
0.429 |
|
| 2012 |
Seth PP, Yu J, Jazayeri A, Pallan PS, Allerson CR, Østergaard ME, Liu F, Herdewijn P, Egli M, Swayze EE. Synthesis and antisense properties of fluoro cyclohexenyl nucleic acid (F-CeNA), a nuclease stable mimic of 2'-fluoro RNA. The Journal of Organic Chemistry. 77: 5074-85. PMID 22591005 DOI: 10.1021/Jo300594B |
0.353 |
|
| 2012 |
Egli M. The steric hypothesis for DNA replication and fluorine hydrogen bonding revisited in light of structural data. Accounts of Chemical Research. 45: 1237-46. PMID 22524491 DOI: 10.1021/Ar200303K |
0.41 |
|
| 2012 |
Zhao L, Christov PP, Kozekov ID, Pence MG, Pallan PS, Rizzo CJ, Egli M, Guengerich FP. Replication of N2,3-ethenoguanine by DNA polymerases. Angewandte Chemie (International Ed. in English). 51: 5466-9. PMID 22488769 DOI: 10.1002/Anie.201109004 |
0.357 |
|
| 2012 |
Pallan PS, Marquez VE, Egli M. The conformationally constrained N-methanocarba-dT analogue adopts an unexpected C4'-exo sugar pucker in the structure of a DNA hairpin. Biochemistry. 51: 2639-41. PMID 22409313 DOI: 10.1021/Bi300215K |
0.397 |
|
| 2012 |
Banerjee S, Christov PP, Kozekova A, Rizzo CJ, Egli M, Stone MP. Replication bypass of the trans-4-Hydroxynonenal-derived (6S,8R,11S)-1,N(2)-deoxyguanosine DNA adduct by the sulfolobus solfataricus DNA polymerase IV. Chemical Research in Toxicology. 25: 422-35. PMID 22313351 DOI: 10.1021/Tx200460J |
0.356 |
|
| 2012 |
Egli M, Mori T, Pattanayek R, Xu Y, Qin X, Johnson CH. Dephosphorylation of the core clock protein KaiC in the cyanobacterial KaiABC circadian oscillator proceeds via an ATP synthase mechanism. Biochemistry. 51: 1547-58. PMID 22304631 DOI: 10.1021/Bi201525N |
0.308 |
|
| 2012 |
Pallan PS, Yu J, Allerson CR, Swayze EE, Seth P, Egli M. Insights from crystal structures into the opposite effects on RNA affinity caused by the S- and R-6'-methyl backbone modifications of 3'-fluoro hexitol nucleic acid. Biochemistry. 51: 7-9. PMID 22229409 DOI: 10.1021/Bi201810R |
0.382 |
|
| 2012 |
Yamanaka K, Dorjsuren D, Eoff RL, Egli M, Maloney DJ, Jadhav A, Simeonov A, Lloyd RS. Dose-response activities of (A) candesartan cilexetil, (B) manoalide, and (C) MK-886 on adducted DNAs. Plos One. DOI: 10.1371/Journal.Pone.0045032.G005 |
0.319 |
|
| 2011 |
Kowal EA, Ganguly M, Pallan PS, Marky LA, Gold B, Egli M, Stone MP. Altering the electrostatic potential in the major groove: thermodynamic and structural characterization of 7-deaza-2'-deoxyadenosine:dT base pairing in DNA. The Journal of Physical Chemistry. B. 115: 13925-34. PMID 22059929 DOI: 10.1021/Jp207104W |
0.404 |
|
| 2011 |
Egli M, Pallan PS, Allerson CR, Prakash TP, Berdeja A, Yu J, Lee S, Watt A, Gaus H, Bhat B, Swayze EE, Seth PP. Synthesis, improved antisense activity and structural rationale for the divergent RNA affinities of 3'-fluoro hexitol nucleic acid (FHNA and Ara-FHNA) modified oligonucleotides. Journal of the American Chemical Society. 133: 16642-9. PMID 21919455 DOI: 10.1021/Ja207086X |
0.45 |
|
| 2011 |
Jiang X, Egli M. Use of chromophoric ligands to visually screen co-crystals of putative protein-nucleic acid complexes. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 7.15.1-8. PMID 21901673 DOI: 10.1002/0471142700.Nc0715S46 |
0.358 |
|
| 2011 |
Pattanayek R, Williams DR, Rossi G, Weigand S, Mori T, Johnson CH, Stewart PL, Egli M. Combined SAXS/EM based models of the S. elongatus post-translational circadian oscillator and its interactions with the output His-kinase SasA. Plos One. 6: e23697. PMID 21887298 DOI: 10.1371/Journal.Pone.0023697 |
0.335 |
|
| 2011 |
Banerjee S, Brown KL, Egli M, Stone MP. Bypass of aflatoxin B1 adducts by the Sulfolobus solfataricus DNA polymerase IV. Journal of the American Chemical Society. 133: 12556-68. PMID 21790157 DOI: 10.1021/Ja2015668 |
0.412 |
|
| 2011 |
Manoharan M, Akinc A, Pandey RK, Qin J, Hadwiger P, John M, Mills K, Charisse K, Maier MA, Nechev L, Greene EM, Pallan PS, Rozners E, Rajeev KG, Egli M. Unique gene-silencing and structural properties of 2'-fluoro-modified siRNAs. Angewandte Chemie (International Ed. in English). 50: 2284-8. PMID 21351337 DOI: 10.1002/Anie.201006519 |
0.358 |
|
| 2011 |
Pallan PS, Greene EM, Jicman PA, Pandey RK, Manoharan M, Rozners E, Egli M. Unexpected origins of the enhanced pairing affinity of 2'-fluoro-modified RNA. Nucleic Acids Research. 39: 3482-95. PMID 21183463 DOI: 10.1093/Nar/Gkq1270 |
0.363 |
|
| 2010 |
Pence MG, Choi JY, Egli M, Guengerich FP. Structural basis for proficient incorporation of dTTP opposite O6-methylguanine by human DNA polymerase iota. The Journal of Biological Chemistry. 285: 40666-72. PMID 20961860 DOI: 10.1074/Jbc.M110.183665 |
0.375 |
|
| 2010 |
Seth PP, Allerson CR, Berdeja A, Siwkowski A, Pallan PS, Gaus H, Prakash TP, Watt AT, Egli M, Swayze EE. An exocyclic methylene group acts as a bioisostere of the 2'-oxygen atom in LNA. Journal of the American Chemical Society. 132: 14942-50. PMID 20886816 DOI: 10.1021/Ja105875E |
0.409 |
|
| 2010 |
Irimia A, Loukachevitch LV, Eoff RL, Guengerich FP, Egli M. Metal-ion dependence of the active-site conformation of the translesion DNA polymerase Dpo4 from Sulfolobus solfataricus. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 66: 1013-8. PMID 20823515 DOI: 10.1107/S1744309110029374 |
0.438 |
|
| 2010 |
Eoff RL, McGrath CE, Maddukuri L, Salamanca-Pinzón SG, Marquez VE, Marnett LJ, Guengerich FP, Egli M. Selective modulation of DNA polymerase activity by fixed-conformation nucleoside analogues. Angewandte Chemie (International Ed. in English). 49: 7481-5. PMID 20814997 DOI: 10.1002/Anie.201003168 |
0.421 |
|
| 2010 |
Egli M. Diffraction techniques in structural biology. Current Protocols in Nucleic Acid Chemistry / Edited by Serge L. Beaucage ... [Et Al.]. Unit 7.13. PMID 20517991 DOI: 10.1002/0471142700.Nc0713S41 |
0.346 |
|
| 2010 |
Egli M, Pallan PS. The many twists and turns of DNA: template, telomere, tool, and target. Current Opinion in Structural Biology. 20: 262-75. PMID 20381338 DOI: 10.1016/J.Sbi.2010.03.001 |
0.468 |
|
| 2010 |
Egli M, Pallan PS. Crystallographic studies of chemically modified nucleic acids: a backward glance. Chemistry & Biodiversity. 7: 60-89. PMID 20087997 DOI: 10.1002/Cbdv.200900177 |
0.458 |
|
| 2010 |
Eoff RL, Egli M, Guengerich P. Impact of Chemical Adducts on Translesion Synthesis in Replicative and Bypass DNA Polymerases: From Structure to Function The Chemical Biology of Dna Damage. 299-330. DOI: 10.1002/9783527630110.ch13 |
0.308 |
|
| 2009 |
Kolarovic A, Schweizer E, Greene E, Gironda M, Pallan PS, Egli M, Rozners E. Interplay of structure, hydration and thermal stability in formacetal modified oligonucleotides: RNA may tolerate nonionic modifications better than DNA. Journal of the American Chemical Society. 131: 14932-7. PMID 19824732 DOI: 10.1021/Ja904926E |
0.464 |
|
| 2009 |
Pallan PS, Egli M. Pairing geometry of the hydrophobic thymine analogue 2,4-difluorotoluene in duplex DNA as analyzed by X-ray crystallography. Journal of the American Chemical Society. 131: 12548-9. PMID 19685868 DOI: 10.1021/Ja905739J |
0.403 |
|
| 2009 |
Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP. Structure-function relationships in miscoding by Sulfolobus solfataricus DNA polymerase Dpo4: guanine N2,N2-dimethyl substitution produces inactive and miscoding polymerase complexes. The Journal of Biological Chemistry. 284: 17687-99. PMID 19542237 DOI: 10.1074/Jbc.M109014274 |
0.322 |
|
| 2009 |
Irimia A, Eoff RL, Guengerich FP, Egli M. Structural and functional elucidation of the mechanism promoting error-prone synthesis by human DNA polymerase kappa opposite the 7,8-dihydro-8-oxo-2'-deoxyguanosine adduct. The Journal of Biological Chemistry. 284: 22467-80. PMID 19542228 DOI: 10.1074/Jbc.M109.003905 |
0.414 |
|
| 2009 |
Eoff RL, Stafford JB, Szekely J, Rizzo CJ, Egli M, Guengerich FP, Marnett LJ. Structural and functional analysis of Sulfolobus solfataricus Y-family DNA polymerase Dpo4-catalyzed bypass of the malondialdehyde-deoxyguanosine adduct. Biochemistry. 48: 7079-88. PMID 19492857 DOI: 10.1021/Bi9003588 |
0.451 |
|
| 2009 |
Pallan PS, Prakash TP, Li F, Eoff RL, Manoharan M, Egli M. A conformational transition in the structure of a 2'-thiomethyl-modified DNA visualized at high resolution. Chemical Communications (Cambridge, England). 2017-9. PMID 19333476 DOI: 10.1039/B822781K |
0.481 |
|
| 2009 |
Zhang H, Eoff RL, Kozekov ID, Rizzo CJ, Egli M, Guengerich FP. Versatility of Y-family Sulfolobus solfataricus DNA polymerase Dpo4 in translesion synthesis past bulky N2-alkylguanine adducts. The Journal of Biological Chemistry. 284: 3563-76. PMID 19059910 DOI: 10.1074/Jbc.M807778200 |
0.389 |
|
| 2008 |
Pallan PS, Kreutz C, Bosio S, Micura R, Egli M. Effects of N2,N2-dimethylguanosine on RNA structure and stability: crystal structure of an RNA duplex with tandem m2 2G:A pairs. Rna (New York, N.Y.). 14: 2125-35. PMID 18772248 DOI: 10.1261/Rna.1078508 |
0.384 |
|
| 2008 |
Pallan PS, Egli M. Insights into RNA/DNA hybrid recognition and processing by RNase H from the crystal structure of a non-specific enzyme-dsDNA complex. Cell Cycle (Georgetown, Tex.). 7: 2562-9. PMID 18719385 DOI: 10.4161/Cc.7.16.6461 |
0.48 |
|
| 2008 |
Wang Y, Musser SK, Saleh S, Marnett LJ, Egli M, Stone MP. Insertion of dNTPs opposite the 1,N2-propanodeoxyguanosine adduct by Sulfolobus solfataricus P2 DNA polymerase IV. Biochemistry. 47: 7322-34. PMID 18563918 DOI: 10.1021/Bi800152J |
0.434 |
|
| 2008 |
Wang F, Li F, Ganguly M, Marky LA, Gold B, Egli M, Stone MP. A bridging water anchors the tethered 5-(3-aminopropyl)-2'-deoxyuridine amine in the DNA major groove proximate to the N+2 C.G base pair: implications for formation of interstrand 5'-GNC-3' cross-links by nitrogen mustards. Biochemistry. 47: 7147-57. PMID 18549246 DOI: 10.1021/Bi800375M |
0.318 |
|
| 2008 |
Pattanayek R, Williams DR, Pattanayek S, Mori T, Johnson CH, Stewart PL, Egli M. Structural model of the circadian clock KaiB-KaiC complex and mechanism for modulation of KaiC phosphorylation. The Embo Journal. 27: 1767-78. PMID 18497745 DOI: 10.1038/Emboj.2008.104 |
0.322 |
|
| 2008 |
Pallan PS, Ittig D, Héroux A, Wawrzak Z, Leumann CJ, Egli M. Crystal structure of tricyclo-DNA: an unusual compensatory change of two adjacent backbone torsion angles. Chemical Communications (Cambridge, England). 883-5. PMID 18253536 DOI: 10.1039/B716390H |
0.464 |
|
| 2007 |
Irimia A, Eoff RL, Pallan PS, Guengerich FP, Egli M. Structure and activity of Y-class DNA polymerase DPO4 from Sulfolobus solfataricus with templates containing the hydrophobic thymine analog 2,4-difluorotoluene. The Journal of Biological Chemistry. 282: 36421-33. PMID 17951245 DOI: 10.1074/Jbc.M707267200 |
0.468 |
|
| 2007 |
Pallan PS, Lubini P, Bolli M, Egli M. Backbone-base inclination as a fundamental determinant of nucleic acid self- and cross-pairing. Nucleic Acids Research. 35: 6611-24. PMID 17905816 DOI: 10.1093/Nar/Gkm612 |
0.492 |
|
| 2007 |
Li F, Pallan PS, Maier MA, Rajeev KG, Mathieu SL, Kreutz C, Fan Y, Sanghvi J, Micura R, Rozners E, Manoharan M, Egli M. Crystal structure, stability and in vitro RNAi activity of oligoribonucleotides containing the ribo-difluorotoluyl nucleotide: insights into substrate requirements by the human RISC Ago2 enzyme. Nucleic Acids Research. 35: 6424-38. PMID 17881374 DOI: 10.1093/Nar/Gkm664 |
0.422 |
|
| 2007 |
Eoff RL, Irimia A, Angel KC, Egli M, Guengerich FP. Hydrogen bonding of 7,8-dihydro-8-oxodeoxyguanosine with a charged residue in the little finger domain determines miscoding events in Sulfolobus solfataricus DNA polymerase Dpo4. The Journal of Biological Chemistry. 282: 19831-43. PMID 17468100 DOI: 10.1074/Jbc.M702290200 |
0.431 |
|
| 2007 |
Pallan PS, Egli M. Selenium modification of nucleic acids: preparation of oligonucleotides with incorporated 2'-SeMe-uridine for crystallographic phasing of nucleic acid structures. Nature Protocols. 2: 647-51. PMID 17406626 DOI: 10.1038/Nprot.2007.75 |
0.376 |
|
| 2007 |
Pallan PS, Egli M. Selenium modification of nucleic acids: preparation of phosphoroselenoate derivatives for crystallographic phasing of nucleic acid structures. Nature Protocols. 2: 640-6. PMID 17406625 DOI: 10.1038/Nprot.2007.74 |
0.322 |
|
| 2007 |
Pallan PS, Lubini P, Egli M. A left-handed supramolecular assembly around a right-handed screw axis in the crystal structure of homo-DNA. Chemical Communications (Cambridge, England). 1447-9. PMID 17389988 DOI: 10.1039/B614983A |
0.461 |
|
| 2007 |
Egli M, Sarkhel S. Lone pair-aromatic interactions: to stabilize or not to stabilize. Accounts of Chemical Research. 40: 197-205. PMID 17370991 DOI: 10.1021/Ar068174U |
0.405 |
|
| 2007 |
Eoff RL, Angel KC, Egli M, Guengerich FP. Molecular basis of selectivity of nucleoside triphosphate incorporation opposite O6-benzylguanine by sulfolobus solfataricus DNA polymerase Dpo4: steady-state and pre-steady-state kinetics and x-ray crystallography of correct and incorrect pairing. The Journal of Biological Chemistry. 282: 13573-84. PMID 17337730 DOI: 10.1074/Jbc.M700656200 |
0.355 |
|
| 2007 |
Egli M, Pallan PS. Insights from crystallographic studies into the structural and pairing properties of nucleic acid analogs and chemically modified DNA and RNA oligonucleotides. Annual Review of Biophysics and Biomolecular Structure. 36: 281-305. PMID 17288535 DOI: 10.1146/Annurev.Biophys.36.040306.132556 |
0.454 |
|
| 2007 |
Loukachevitch LV, Egli M. Crystallization and preliminary X-ray analysis of Escherichia coli RNase HI-dsRNA complexes. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 63: 84-8. PMID 17277445 DOI: 10.1107/S1744309106055461 |
0.421 |
|
| 2007 |
Egli M, Lubini P, Pallan PS. The long and winding road to the structure of homo-DNA. Chemical Society Reviews. 36: 31-45. PMID 17173143 DOI: 10.1039/B606807C |
0.474 |
|
| 2007 |
Luka Z, Pakhomova S, Loukachevitch LV, Egli M, Newcomer ME, Wagner C. 5-Methyltetrahydrofolate is bound in intersubunit areas of rat liver folate-binding protein glycine N-methyltransferase Journal of Biological Chemistry. 282: 4069-4075. PMID 17158459 DOI: 10.1074/Jbc.M610384200 |
0.352 |
|
| 2007 |
Eoff RL, Irimia A, Egli M, Guengerich FP. Sulfolobus solfataricus DNA polymerase Dpo4 is partially inhibited by "wobble" pairing between O6-methylguanine and cytosine, but accurate bypass is preferred. The Journal of Biological Chemistry. 282: 1456-67. PMID 17105728 DOI: 10.1074/Jbc.M609661200 |
0.34 |
|
| 2006 |
Xia J, Noronha A, Toudjarska I, Li F, Akinc A, Braich R, Frank-Kamenetsky M, Rajeev KG, Egli M, Manoharan M. Gene silencing activity of siRNAs with a ribo-difluorotoluyl nucleotide. Acs Chemical Biology. 1: 176-83. PMID 17163665 DOI: 10.1021/Cb600063P |
0.426 |
|
| 2006 |
Egli M, Pallan PS, Pattanayek R, Wilds CJ, Lubini P, Minasov G, Dobler M, Leumann CJ, Eschenmoser A. Crystal structure of homo-DNA and nature's choice of pentose over hexose in the genetic system. Journal of the American Chemical Society. 128: 10847-56. PMID 16910680 DOI: 10.1021/Ja062548X |
0.489 |
|
| 2006 |
Pallan PS, von Matt P, Wilds CJ, Altmann KH, Egli M. RNA-Binding affinities and crystal structure of oligonucleotides containing five-atom amide-based backbone structures. Biochemistry. 45: 8048-57. PMID 16800629 DOI: 10.1021/Bi060354O |
0.488 |
|
| 2006 |
Irimia A, Zang H, Loukachevitch LV, Eoff RL, Guengerich FP, Egli M. Calcium is a cofactor of polymerization but inhibits pyrophosphorolysis by the Sulfolobus solfataricus DNA polymerase Dpo4. Biochemistry. 45: 5949-56. PMID 16681366 DOI: 10.1021/Bi052511+ |
0.348 |
|
| 2006 |
Pattanayek R, Williams DR, Pattanayek S, Xu Y, Mori T, Johnson CH, Stewart PL, Egli M. Analysis of KaiA-KaiC protein interactions in the cyano-bacterial circadian clock using hybrid structural methods. The Embo Journal. 25: 2017-28. PMID 16628225 DOI: 10.1038/Sj.Emboj.7601086 |
0.304 |
|
| 2006 |
Li F, Sarkhel S, Wilds CJ, Wawrzak Z, Prakash TP, Manoharan M, Egli M. 2'-Fluoroarabino- and arabinonucleic acid show different conformations, resulting in deviating RNA affinities and processing of their heteroduplexes with RNA by RNase H. Biochemistry. 45: 4141-52. PMID 16566588 DOI: 10.1021/Bi052322R |
0.438 |
|
| 2006 |
Zang H, Irimia A, Choi JY, Angel KC, Loukachevitch LV, Egli M, Guengerich FP. Efficient and high fidelity incorporation of dCTP opposite 7,8-dihydro-8-oxodeoxyguanosine by Sulfolobus solfataricus DNA polymerase Dpo4. The Journal of Biological Chemistry. 281: 2358-72. PMID 16306039 DOI: 10.1074/Jbc.M510889200 |
0.411 |
|
| 2005 |
Diop-Frimpong B, Prakash TP, Rajeev KG, Manoharan M, Egli M. Stabilizing contributions of sulfur-modified nucleotides: crystal structure of a DNA duplex with 2'-O-[2-(methoxy)ethyl]-2-thiothymidines. Nucleic Acids Research. 33: 5297-307. PMID 16170156 DOI: 10.1093/Nar/Gki823 |
0.51 |
|
| 2005 |
Pallan PS, Marshall WS, Harp J, Jewett FC, Wawrzak Z, Brown BA, Rich A, Egli M. Crystal structure of a luteoviral RNA pseudoknot and model for a minimal ribosomal frameshifting motif. Biochemistry. 44: 11315-22. PMID 16114868 DOI: 10.1021/Bi051061I |
0.542 |
|
| 2005 |
Haeberli P, Berger I, Pallan PS, Egli M. Syntheses of 4'-thioribonucleosides and thermodynamic stability and crystal structure of RNA oligomers with incorporated 4'-thiocytosine. Nucleic Acids Research. 33: 3965-3975. PMID 16027443 DOI: 10.1093/Nar/Gki704 |
0.431 |
|
| 2005 |
Egli M, Minasov G, Tereshko V, Pallan PS, Teplova M, Inamati GB, Lesnik EA, Owens SR, Ross BS, Prakash TP, Manoharan M. Probing the influence of stereoelectronic effects on the biophysical properties of oligonucleotides: comprehensive analysis of the RNA affinity, nuclease resistance, and crystal structure of ten 2'-O-ribonucleic acid modifications. Biochemistry. 44: 9045-57. PMID 15966728 DOI: 10.1021/Bi050574M |
0.444 |
|
| 2005 |
Zang H, Goodenough AK, Choi JY, Irimia A, Loukachevitch LV, Kozekov ID, Angel KC, Rizzo CJ, Egli M, Guengerich FP. DNA adduct bypass polymerization by Sulfolobus solfataricus DNA polymerase Dpo4: analysis and crystal structures of multiple base pair substitution and frameshift products with the adduct 1,N2-ethenoguanine. The Journal of Biological Chemistry. 280: 29750-64. PMID 15965231 DOI: 10.1074/Jbc.M504756200 |
0.389 |
|
| 2004 |
Egli M. Nucleic acid crystallography: current progress. Current Opinion in Chemical Biology. 8: 580-591. PMID 15556400 DOI: 10.1016/J.Cbpa.2004.09.004 |
0.47 |
|
| 2004 |
Pattanayek R, Sethaphong L, Pan C, Prhavc M, Prakash TP, Manoharan M, Egli M. Structural rationalization of a large difference in RNA affinity despite a small difference in chemistry between two 2'-O-modified nucleic acid analogues. Journal of the American Chemical Society. 126: 15006-7. PMID 15547979 DOI: 10.1021/Ja044637K |
0.406 |
|
| 2004 |
Egli M. “Deoxyribo Nanonucleic Acid”: Antiparallel, Parallel, and Unparalleled Chemistry & Biology. 11: 1027-1029. PMID 15324800 DOI: 10.1016/J.Chembiol.2004.08.002 |
0.43 |
|
| 2004 |
Pattanayek R, Wang J, Mori T, Xu Y, Johnson CH, Egli M. Visualizing a circadian clock protein: crystal structure of KaiC and functional insights. Molecular Cell. 15: 375-88. PMID 15304218 DOI: 10.1016/J.Molcel.2004.07.013 |
0.362 |
|
| 2004 |
Prakash TP, Püschl A, Lesnik E, Mohan V, Tereshko V, Egli M, Manoharan M. 2'-O-[2-(guanidinium)ethyl]-modified oligonucleotides: stabilizing effect on duplex and triplex structures. Organic Letters. 6: 1971-4. PMID 15176796 DOI: 10.1021/Ol049470E |
0.42 |
|
| 2003 |
Sarkhel S, Rich A, Egli M. Water-nucleobase "stacking": H-pi and lone pair-pi interactions in the atomic resolution crystal structure of an RNA pseudoknot. Journal of the American Chemical Society. 125: 8998-9. PMID 15369340 DOI: 10.1021/Ja0357801 |
0.52 |
|
| 2003 |
Pallan PS, Wilds CJ, Wawrzak Z, Krishnamurthy R, Eschenmoser A, Egli M. Why does TNA cross-pair more strongly with RNA than with DNA? an answer from X-ray analysis. Angewandte Chemie (International Ed. in English). 42: 5893-5. PMID 14673929 DOI: 10.1002/Anie.200352553 |
0.502 |
|
| 2003 |
Egli M, Tereshko V, Mushudov GN, Sanishvili R, Liu X, Lewis FD. Face-to-face and edge-to-face pi-pi interactions in a synthetic DNA hairpin with a stilbenediether linker. Journal of the American Chemical Society. 125: 10842-9. PMID 12952463 DOI: 10.1021/Ja0355527 |
0.443 |
|
| 2003 |
Prhavc M, Prakash TP, Minasov G, Cook PD, Egli M, Manoharan M. 2'-O-[2-[2-(N,N-dimethylamino)ethoxy]ethyl] modified oligonucleotides: symbiosis of charge interaction factors and stereoelectronic effects. Organic Letters. 5: 2017-20. PMID 12790517 DOI: 10.1021/Ol0340991 |
0.348 |
|
| 2003 |
Egli M, Sarkhel S, Minasov G, Rich A. Structure and function of the ribosomal frameshifting pseudoknot RNA from beet western yellow virus Helvetica Chimica Acta. 86: 1709-1727. DOI: 10.1002/Hlca.200390142 |
0.547 |
|
| 2003 |
Wilds CJ, Maier MA, Manoharan M, Egli M. Structural basis for recognition of guanosine by a synthetic tricyclic cytosine analogue: Guanidinium G-clamp Helvetica Chimica Acta. 86: 966-978. DOI: 10.1002/Hlca.200390114 |
0.433 |
|
| 2002 |
Wilds CJ, Maier MA, Tereshko V, Manoharan M, Egli M. Direct observation of a cytosine analogue that forms five hydrogen bonds to guanosine: guanidino G-clamp. Angewandte Chemie (International Ed. in English). 41: 115-7. PMID 12491456 DOI: 10.1002/1521-3773(20020104)41:1<115::Aid-Anie115>3.0.Co;2-R |
0.371 |
|
| 2002 |
Wilds CJ, Pattanayek R, Pan C, Wawrzak Z, Egli M. Selenium-assisted nucleic acid crystallography: use of phosphoroselenoates for MAD phasing of a DNA structure. Journal of the American Chemical Society. 124: 14910-6. PMID 12475332 DOI: 10.1021/Ja021058B |
0.425 |
|
| 2002 |
Teplova M, Wilds CJ, Wawrzak Z, Tereshko V, Du Q, Carrasco N, Huang Z, Egli M. Covalent incorporation of selenium into oligonucleotides for X-ray crystal structure determination via MAD: proof of principle. Multiwavelength anomalous dispersion. Biochimie. 84: 849-58. PMID 12458077 DOI: 10.1016/S0300-9084(02)01440-2 |
0.43 |
|
| 2002 |
Wilds CJ, Wawrzak Z, Krishnamurthy R, Eschenmoser A, Egli M. Crystal structure of a B-form DNA duplex containing (L)-alpha-threofuranosyl (3'-->2') nucleosides: a four-carbon sugar is easily accommodated into the backbone of DNA. Journal of the American Chemical Society. 124: 13716-21. PMID 12431101 DOI: 10.1021/Ja0207807 |
0.492 |
|
| 2002 |
Prakash TP, Manoharan M, Kawasaki AM, Fraser AS, Lesnik EA, Sioufi N, Leeds JM, Teplova M, Egli M. 2'-O-[2-(methylthio)ethyl]-modified oligonucleotide: an analogue of 2'-O-[2-(methoxy)-ethyl]-modified oligonucleotide with improved protein binding properties and high binding affinity to target RNA. Biochemistry. 41: 11642-8. PMID 12269806 DOI: 10.1021/Bi020264T |
0.332 |
|
| 2002 |
Egli M. DNA-cation interactions: quo vadis? Chemistry & Biology. 9: 277-286. PMID 11927253 DOI: 10.1016/S1074-5521(02)00116-3 |
0.364 |
|
| 2002 |
Egli M, Minasov G, Su L, Rich A. Metal ions and flexibility in a viral RNA pseudoknot at atomic resolution. Proceedings of the National Academy of Sciences of the United States of America. 99: 4302-7. PMID 11904368 DOI: 10.1073/Pnas.062055599 |
0.526 |
|
| 2002 |
Egli M. Covalent incorporation of selenium into oligonucleotides for X-ray crystal structure determination via MAD Acta Crystallographica Section A. 58: 55-55. DOI: 10.1107/S0108767302087299 |
0.336 |
|
| 2001 |
Tereshko V, Teplova M, Brunzelle J, Watterson DM, Egli M. Crystal structures of the catalytic domain of human protein kinase associated with apoptosis and tumor suppression. Nature Structural Biology. 8: 899-907. PMID 11573098 DOI: 10.1038/Nsb1001-899 |
0.331 |
|
| 2001 |
Wilds CJ, Minasov G, Natt F, Matt Pv, Altmann KH, Egli M. Studies of a chemically modified oligodeoxynucleotide containing a 5-atom amide backbone which exhibits improved binding to RNA. Nucleosides, Nucleotides & Nucleic Acids. 20: 991-994. PMID 11563161 DOI: 10.1081/Ncn-100002475 |
0.342 |
|
| 2001 |
Tereshko V, Wallace ST, Usman N, Wincott FE, Egli M. X-ray crystallographic observation of "in-line" and "adjacent" conformations in a bulged self-cleaving RNA/DNA hybrid. Rna. 7: 405-420. PMID 11333021 DOI: 10.1017/S1355838201001935 |
0.418 |
|
| 2001 |
Tereshko V, Wilds CJ, Minasov G, Prakash TP, Maier MA, Howard A, Wawrzak Z, Manoharan M, Egli M. Detection of alkali metal ions in DNA crystals using state-of-the-art X-ray diffraction experiments Nucleic Acids Research. 29: 1208-1215. PMID 11222771 DOI: 10.1093/Nar/29.5.1208 |
0.358 |
|
| 2001 |
Egli M, Minasov G, Teplova M, Kumar R, Wengel J. X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer Journal of the Chemical Society, Chemical Communications. 651-652. DOI: 10.2210/Pdb1I5W/Pdb |
0.456 |
|
| 2001 |
Egli M, Minasov G, Teplova M, Kumar R, Wengel J. X-ray crystal structure of a locked nucleic acid (LNA) duplex composed of a palindromic 10-mer DNA strand containing one LNA thymine monomer Chemical Communications. 2001: 651-652. DOI: 10.1039/B009447L |
0.505 |
|
| 2000 |
Teplova M, Tereshko V, Sanishvili R, Joachimiak A, Bushueva T, Anderson WF, Egli M. The structure of the yrdC gene product from Escherichia coli reveals a new fold and suggests a role in RNA binding. Protein Science. 9: 2557-2566. PMID 11206077 DOI: 10.1110/Ps.9.12.2557 |
0.388 |
|
| 2000 |
Minasov G, Matulic-Adamic J, Wilds CJ, Haeberli P, Usman N, Beigelman L, Egli M. Crystal structure of an RNA duplex containing phenyl-ribonucleotides, hydrophobic isosteres of the natural pyrimidines. Rna. 6: 1516-1528. PMID 11105752 DOI: 10.1017/S1355838200001114 |
0.455 |
|
| 2000 |
Egli M, Gryaznov SM. Synthetic oligonucleotides as RNA mimetics: 2'-modified Rnas and N3'-->P5' phosphoramidates. Cellular and Molecular Life Sciences. 57: 1440-1456. PMID 11078022 DOI: 10.1007/Pl00000628 |
0.392 |
|
| 2000 |
Minasov G, Teplova M, Stewart GC, Koonin EV, Anderson WF, Egli M. Functional implications from crystal structures of the conserved Bacillus subtilis protein Maf with and without dUTP Proceedings of the National Academy of Sciences of the United States of America. 97: 6328-6333. PMID 10841541 DOI: 10.1073/Pnas.97.12.6328 |
0.352 |
|
| 2000 |
Minasov G, Teplova M, Nielsen P, Wengel J, Egli M. Structural basis of cleavage by RNase H of hybrids of arabinonucleic acids and RNA. Biochemistry. 39: 3525-3532. PMID 10736151 DOI: 10.1021/Bi992792J |
0.418 |
|
| 1999 |
Teplova M, Wallace ST, Tereshko V, Minasov G, Symons AM, Cook PD, Manoharan M, Egli M. Structural origins of the exonuclease resistance of a zwitterionic RNA. Proceedings of the National Academy of Sciences of the United States of America. 96: 14240-5. PMID 10588690 DOI: 10.1073/Pnas.96.25.14240 |
0.469 |
|
| 1999 |
Minasov G, Tereshko V, Egli M. Atomic-resolution crystal structures of B-DNA reveal specific influences of divalent metal ions on conformation and packing. Journal of Molecular Biology. 291: 83-99. PMID 10438608 DOI: 10.1006/Jmbi.1999.2934 |
0.44 |
|
| 1999 |
Teplova M, Minasov G, Tereshko V, Inamati GB, Cook PD, Manoharan M, Egli M. Crystal structure and improved antisense properties of 2'-O-(2-methoxyethyl)-RNA. Nature Structural Biology. 6: 535-9. PMID 10360355 DOI: 10.1038/9304 |
0.428 |
|
| 1999 |
Su L, Chen L, Egli M, Berger JM, Rich A. Minor groove RNA triplex in the crystal structure of a ribosomal frameshifting viral pseudoknot. Nature Structural Biology. 6: 285-92. PMID 10074948 DOI: 10.1038/6722 |
0.538 |
|
| 1999 |
Berger I, Egli M, Spackova N, Sponer J, Rich A. Four-stranded intercalated cytosine-rich molecules: Novel insights into DNA structure and stability Nucleosides and Nucleotides. 18: 1583-1585. DOI: 10.1080/07328319908044791 |
0.581 |
|
| 1999 |
Tereshko V, Minasov aG, Egli M. The Dickerson-Drew B-DNA Dodecamer Revisited at Atomic Resolution J. Am. Chem. Soc. 1999, 121, 470−471]. A “Hydrat-Ion” Spine in a B-DNA Minor Groove [J. Am. Chem. Soc. 1999, 121, 3590−3595 Journal of the American Chemical Society. 121: 6970-6970. DOI: 10.1021/Ja995519D |
0.331 |
|
| 1999 |
Lewis FD, Liu X, Wu Y, Miller SE, Wasielewski MR, Letsinger RL, Sanishvili R, Joachimiak A, Tereshko V, Egli M. Structure and photoinduced electron transfer in exceptionally stable synthetic DNA hairpins with stilbenediether linkers [18] Journal of the American Chemical Society. 121: 9905-9906. DOI: 10.1021/Ja991934U |
0.451 |
|
| 1999 |
Tereshko V, Minasov G, Egli M. A "Hydrat-Ion" Spine in a B-DNA Minor Groove Journal of the American Chemical Society. 121: 3590-3595. DOI: 10.1021/Ja984346+ |
0.388 |
|
| 1998 |
Benner SA, Battersby TR, Eschgfaller B, Hutter D, Kodra JT, Lutz S, Arslan T, Baschlin DK, Blattler M, Egli M, Hammer C, Held HA, Horlacher J, Huang Z, Hyrup B, et al. Redesigning nucleic acids. Pure and Applied Chemistry. Chimie Pure Et Appliquã©E. 70: 263-6. PMID 11542721 DOI: 10.1351/Pac199870020263 |
0.397 |
|
| 1998 |
Egli M, Tereshko V, Teplova M, Minasov G, Joachimiak A, Sanishvili R, Weeks CM, Miller R, Maier MA, An H, Dan Cook P, Manoharan M. X-ray crystallographic analysis of the hydration of A- and B-form DNA at atomic resolution Biopolymers. 48: 234-252. PMID 10699842 DOI: 10.1002/(Sici)1097-0282(1998)48:4<234::Aid-Bip4>3.0.Co;2-H |
0.454 |
|
| 1998 |
Maltseva TV, Altmann K-, Egli M, Chattopadhyaya J. The residence time of the bound water in the hydrophobic minor groove of the carbocyclic-nucleoside analogs of Dickerson-Drew dodecamers. Journal of Biomolecular Structure & Dynamics. 16: 569-578. PMID 10052614 DOI: 10.1080/07391102.1998.10508270 |
0.316 |
|
| 1998 |
Denisov AY, Zamaratski EV, Maltseva TV, Sandström A, Bekiroglu S, Altmann K, Egli M, Chattopadhyaya J. The solution conformation of a carbocyclic analog of the Dickerson-Drew dodecamer: comparison with its own X-ray structure and that of the NMR structure of the native counterpart. Journal of Biomolecular Structure & Dynamics. 16: 547-568. PMID 10052613 DOI: 10.1080/07391102.1998.10508269 |
0.38 |
|
| 1998 |
Tereshko V, Portmann S, Tay EC, Martin P, Natt F, Altmann K, Egli M. Correlating structure and stability of DNA duplexes with incorporated 2'-O-modified RNA analogues. Biochemistry. 37: 10626-10634. PMID 9692952 DOI: 10.1021/Bi980392A |
0.395 |
|
| 1998 |
Egli M. Conformational preorganization, hydration, and nucleic acid duplex stability. Antisense & Nucleic Acid Drug Development. 8: 123-128. PMID 9593050 DOI: 10.1089/Oli.1.1998.8.123 |
0.32 |
|
| 1998 |
Berger I, Tereshko V, Ikeda H, Marquez VE, Egli M. Crystal structures of B-DNA with incorporated 2′-deoxy-2′-fluoro-arabino-furanosyl thymines: Implications of conformational preorganization for duplex stability Nucleic Acids Research. 26: 2473-2480. PMID 9580702 DOI: 10.1093/Nar/26.10.2473 |
0.468 |
|
| 1998 |
Tereshko V, Minasov G, Egli M. The Dickerson-Drew B-DNA Dodecamer Revisited-At Atomic Resolution Journal of the American Chemical Society. 121: 470-471. DOI: 10.1021/Ja9832919 |
0.463 |
|
| 1998 |
Tereshko V, Gryaznov S, Egli M. Consequences of Replacing the DNA 3‘-Oxygen by an Amino Group: High-Resolution Crystal Structure of a Fully Modified N3‘ → P5‘ Phosphoramidate DNA Dodecamer Duplex† Journal of the American Chemical Society. 120: 269-283. DOI: 10.1021/Ja971962H |
0.469 |
|
| 1997 |
Allemann RK, Egli M. DNA recognition and bending Chemistry & Biology. 4: 643-650. PMID 9331406 DOI: 10.1016/S1074-5521(97)90218-0 |
0.407 |
|
| 1997 |
Berger I, Egli M. The Role of Backbone Oxygen Atoms in the Organization of Nucleic Acid Tertiary Structure: Zippers, Networks, Clamps, and C‐H…︁O Hydrogen Bonds Chemistry: a European Journal. 3: 1400-1404. DOI: 10.1002/Chem.19970030905 |
0.431 |
|
| 1997 |
Egli M. In Vitro Selected Receptors Rationalized: The First 3D Structures of RNA Aptamer/Substrate Complexes Angewandte Chemie. 36: 480-482. DOI: 10.1002/Anie.199704801 |
0.339 |
|
| 1996 |
Berger I, Egli M, Rich A. Inter-strand C-H⋯O hydrogen bonds stabilizing four-stranded intercalated molecules: Stereoelectronic effects of O4′ in cytosine-rich DNA Proceedings of the National Academy of Sciences of the United States of America. 93: 12116-12121. PMID 8901542 DOI: 10.1073/Pnas.93.22.12116 |
0.591 |
|
| 1996 |
Portmann S, Grimm S, Workman C, Usman N, Egli M. Crystal structures of an A-form duplex with single-adenosine bulges and a conformational basis for site-specific RNA self-cleavage Chemistry and Biology. 3: 173-184. PMID 8807843 DOI: 10.1016/S1074-5521(96)90260-4 |
0.439 |
|
| 1996 |
Egli M, Portmann S, Usman N. RNA Hydration: A Detailed Look†,‡ Biochemistry. 35: 8489-8494. PMID 8679609 DOI: 10.1021/Bi9607214 |
0.457 |
|
| 1996 |
Portmann S, Altmann K, Reynes N, Egli M. Crystal Structures of Oligodeoxyribonucleotides Containing 6'-alpha-Methyl and 6'-alpha-Hydroxy Carbocyclic Thymidines Journal of the American Chemical Society. 119: 2396-2403. DOI: 10.2210/Pdb290D/Pdb |
0.42 |
|
| 1996 |
Portmann S, Usman N, Egli M. The Crystal Structure of r(CCCCGGGG) in Two Distinct Lattices Biochemistry. 34: 7569-7575. DOI: 10.2210/Pdb1Rxa/Pdb |
0.453 |
|
| 1996 |
Egli M. Structural Aspects of Nucleic Acid Analogs and Antisense Oligonucleotides Angewandte Chemie. 35: 1894-1909. DOI: 10.1002/Anie.199618941 |
0.464 |
|
| 1996 |
Egli M. Die Strukturen von Nucleinsäureanaloga und Antisense‐Oligonucleotiden Angewandte Chemie. 108: 2020-2036. DOI: 10.1002/Ange.19961081705 |
0.359 |
|
| 1995 |
Egli M, Portmann S, Tracz D, Workman C, Usman N. Crystallization and preliminary X-ray diffraction analysis of double-helical RNA octamers. Acta Crystallographica Section D-Biological Crystallography. 51: 1065-1070. PMID 15299775 DOI: 10.1107/S0907444995003817 |
0.362 |
|
| 1995 |
Egli M, Gessner RV. Stereoelectronic effects of deoxyribose O4' on DNA conformation. Proceedings of the National Academy of Sciences of the United States of America. 92: 180-184. PMID 7816812 DOI: 10.1073/Pnas.92.1.180 |
0.45 |
|
| 1995 |
Hyrup B, Richert C, Schulte-herbrüggen T, Benner SA, Egli M. X-ray crystal struture of a dimethylene sulfone-bridged ribonucleotide dimer in a single-stranded state Nucleic Acids Research. 23: 2427-2433. PMID 7543197 DOI: 10.1093/Nar/23.13.2427 |
0.401 |
|
| 1995 |
Roughton AL, Portmann S, Benner SA, Egli M. Crystal structure of a dimethylene sulfone-linked ribodinucleotide analog Journal of the American Chemical Society. 117: 7249-7250. DOI: 10.1021/Ja00132A027 |
0.348 |
|
| 1995 |
Zhang S, Egli M. A proposed complementary pairing mode between single-stranded nucleic acids and β-stranded peptides: A possible pathway for generating complex biological molecules Complexity. 1: 49-56. DOI: 10.1002/Cplx.6130010113 |
0.393 |
|
| 1994 |
Lubini P, Zürcher W, Egli M. Stabilizing effects of the RNA 2′-substituent: crystal structure of an oligodeoxynucleotide duplex containing 2′-O-methylated adenosines Chemistry & Biology. 1: 39-45. PMID 9383369 DOI: 10.1016/1074-5521(94)90039-6 |
0.434 |
|
| 1994 |
Gessner RV, Quigley GJ, Egli M. Comparative studies of high resolution Z-DNA crystal structures. Part 1: Common hydration patterns of alternating dC-dG. Journal of Molecular Biology. 236: 1154-1168. PMID 8120893 DOI: 10.1016/0022-2836(94)90018-3 |
0.386 |
|
| 1994 |
Bancroft D, Williams LD, Rich A, Egli M. The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove. Biochemistry. 33: 1073-86. PMID 8110738 DOI: 10.2210/Pdb131D/Pdb |
0.702 |
|
| 1994 |
Zhang S, Egli M. A hypothesis: reciprocal information transfer between oligoribonucleotides and oligopeptides in prebiotic molecular evolution. Origins of Life and Evolution of Biospheres. 24: 495-505. PMID 7991236 DOI: 10.1007/Bf01582033 |
0.326 |
|
| 1993 |
Usman N, Egli M, Rich A. Large scale chemical synthesis, purification and crystallization of RNA-DNA chimeras. Nucleic Acids Research. 20: 6695-9. PMID 1282704 DOI: 10.1093/Nar/20.24.6695 |
0.585 |
|
| 1993 |
Egli M, Usman N, Rich A. Conformational influence of the ribose 2'-hydroxyl group: Crystal structures of DNA-RNA chimeric duplexes Biochemistry. 32: 3221-3237. DOI: 10.2210/Pdb1D87/Pdb |
0.619 |
|
| 1993 |
Egli M, Lubini P, Bolli M, Dobler M, Leumann C. Crystal structure of a parallel-stranded duplex of a deoxycytidylyl-(3'-5')-deoxycytidine analog containing intranucleosidyl C(3')-C(5') ethylene bridges Journal of the American Chemical Society. 115: 5855-5856. DOI: 10.1021/Ja00066A076 |
0.362 |
|
| 1992 |
Egli M, Usman N, Zhang SG, Rich A. Crystal structure of an Okazaki fragment at 2-A resolution. Proceedings of the National Academy of Sciences of the United States of America. 89: 534-8. PMID 1370582 DOI: 10.1073/Pnas.89.2.534 |
0.617 |
|
| 1992 |
Seebach D, Amatsch B, Amstutz R, Beck AK, Doler M, Egli M, Fitzi R, Gautschi M, Herradön B, Hidber PC, Irwin JJ, Locher R, Maestro M, Maetzke T, Mouriño A, et al. Structure and Reactivity of Five‐ and Six‐Ring N, N‐, N, O‐, and O, O‐acetals: A lesson in allylic 1, 3‐strain (A1, 3 strain) Helvetica Chimica Acta. 75: 913-934. DOI: 10.1002/Hlca.19920750326 |
0.307 |
|
| 1991 |
Gao Q, Williams LD, Egli M, Rabinovich D, Chen SL, Quigley GJ, Rich A. Drug-induced DNA repair: X-ray structure of a DNA-ditercalinium complex. Proceedings of the National Academy of Sciences of the United States of America. 88: 2422-6. PMID 2006181 DOI: 10.1073/Pnas.88.6.2422 |
0.674 |
|
| 1991 |
Egli M, Williams LD, Frederick CA, Rich A. DNA-nogalamycin interactions. Biochemistry. 30: 1364-72. PMID 1991116 DOI: 10.1021/Bi00219A029 |
0.706 |
|
| 1991 |
Egli M, Williams LD, Gao Q, Rich A. Structure of the pure-spermine form of Z-DNA (magnesium free) at 1-A resolution. Biochemistry. 30: 11388-402. PMID 1742278 DOI: 10.1021/Bi00112A005 |
0.715 |
|
| 1990 |
Williams LD, Egli M, Qi G, Bash P, van der Marel GA, van Boom JH, Rich A, Frederick CA. Structure of nogalamycin bound to a DNA hexamer. Proceedings of the National Academy of Sciences of the United States of America. 87: 2225-9. PMID 2315315 DOI: 10.1073/Pnas.87.6.2225 |
0.698 |
|
| 1990 |
Egli M, Gessner RV, Williams LD, Quigley GJ, van der Marel GA, van Boom JH, Rich A, Frederick CA. Atomic-resolution structure of the cellulose synthase regulator cyclic diguanylic acid. Proceedings of the National Academy of Sciences of the United States of America. 87: 3235-9. PMID 2158107 DOI: 10.1073/Pnas.87.8.3235 |
0.652 |
|
| 1990 |
Williams LD, Egli M, Ughetto G, van der Marel GA, van Boom JH, Quigley GJ, Wang AH, Rich A, Frederick CA. Structure of 11-deoxydaunomycin bound to DNA containing a phosphorothioate. Journal of Molecular Biology. 215: 313-20. PMID 2152325 DOI: 10.1016/S0022-2836(05)80349-3 |
0.691 |
|
| 1989 |
Seebach D, Brändli U, Müller H, Dobler M, Egli M, Przybylski M, Schneider K. On the Macrolactonization of β-Hydroxy Acids. Crystal structures of the pentolide and the hexolide from (R)-3-hydroxybutanoic acid. Molecular modeling studies of the tetrolide Helvetica Chimica Acta. 72: 1704-1717. DOI: 10.1002/Hlca.19890720807 |
0.379 |
|
| 1989 |
Egli M, Dobler M. Structural Aspects of the Enantioselectivity of Tartrates with α‐Amino‐alcohol Salts. Part II. Crystal structures of (1R, 2S)‐norephedrine hydrochloride and (1R, 2R)‐ norpseudoephedrine hydrochloride Helvetica Chimica Acta. 72: 1151-1157. DOI: 10.1002/Hlca.19890720533 |
0.31 |
|
| 1989 |
Egli M, Dobler M. Structural Aspects of the Enantioselectivity of Tartrates with α‐Amino‐alcohol Salts part. I. Crystal structures of eleven tartaric‐acid diesters Helvetica Chimica Acta. 72: 1136-1150. DOI: 10.1002/Hlca.19890720532 |
0.387 |
|
| 1989 |
PRELOG V, KOVACEVIC M, EGLI M. ChemInform Abstract: Lipophilic Tartaric Acid Esters as Enantioselective Ionophores Cheminform. 20. DOI: 10.1002/CHIN.198948350 |
0.469 |
|
| 1989 |
Prelog V, Kovačević M, Egli M. Lipophilic Tartaric Acid Esters as Enantioselective Ionophores Angewandte Chemie International Edition in English. 28: 1147-1152. DOI: 10.1002/Anie.198911473 |
0.559 |
|
| 1989 |
Prelog V, Kovačević M, Egli M. Lipophile Weinsäureester als enantioselektive Ionophore Angewandte Chemie. 101: 1173-1178. DOI: 10.1002/Ange.19891010904 |
0.506 |
|
| 1987 |
Thiele K, Zirngibl L, Pfenninger MH, Egli M, Dobler M. Antimykotisch wirksame Imidazolyl‐alkene: Synthese und Röntgenstrukturanalyse von Omoconazol Helvetica Chimica Acta. 70: 441-444. DOI: 10.1002/Hlca.19870700224 |
0.358 |
|
| 1986 |
Metzger E, Aeschimann R, Egli M, Suter G, Dohner R, Ammann D, Dobler M, Simon W. 3,7-Dioxaazelaamides as Ionophores for Lithium Ion Selective Liquid Membrane Electrodes Helvetica Chimica Acta. 69: 1821-1828. DOI: 10.1002/Hlca.19860690806 |
0.457 |
|
| 1986 |
Egli M, Dobler M. Crystal Structures of Chiral Ionophores: Bis(9,9′-spirobifluorene)-26-crown-4 and -32-crown-6 Helvetica Chimica Acta. 69: 626-631. DOI: 10.1002/Hlca.19860690312 |
0.335 |
|
| 1986 |
Egli M, Dobler M. Crystal Structures of Chiral Ionophores: Bis(9,9′-spirobifluorene)-26-crown-4 and -32-crown-6. Cheminform. 17. DOI: 10.1002/Chin.198631066 |
0.347 |
|
| 1986 |
Egli M, Wallis JD, Dunitz JD. Interactions between Functional Groups. Part III. The Structure ofN,N-Dimethyl-8-nitro-1-naphthaleneamine in Seven Crystalline Environments Helvetica Chimica Acta. 69: 255-266. DOI: 10.1002/Chin.198625053 |
0.495 |
|
| 1986 |
DOBLER M, DUMIC M, EGLI M, PRELOG V. ChemInform Abstract: Chiral Poly(9,9′-spirobifluorene) Crown Ethers. Chemischer Informationsdienst. 17. DOI: 10.1002/Chin.198604206 |
0.526 |
|
| 1985 |
Dobler M, Dumi? M, Egli M, Prelog V. Chiral Poly(9,9?-spirobifluorene) Crown Ethers Angewandte Chemie International Edition in English. 24: 792-794. DOI: 10.1002/Anie.198507921 |
0.521 |
|
| 1985 |
Dobler M, Dumić M, Egli M, Prelog V. Chirale Poly(9,9′-spirobifluoren)-kronenether Angewandte Chemie. 97: 793-794. DOI: 10.1002/Ange.19850970932 |
0.525 |
|
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