| Year |
Citation |
Score |
| 2015 |
Walentiny D, Harris L. Characterization of morphine discriminative stimulus properties in C57BL/6 mice Drug and Alcohol Dependence. 146: e15. DOI: 10.1016/j.drugalcdep.2014.09.721 |
0.313 |
|
| 2014 |
Ben Haddou T, Malfacini D, Calo G, Aceto MD, Harris LS, Traynor JR, Coop A, Schmidhammer H, Spetea M. Exploring pharmacological activities and signaling of morphinans substituted in position 6 as potent agonists interacting with the μ opioid receptor. Molecular Pain. 10: 48. PMID 25059282 DOI: 10.1186/1744-8069-10-48 |
0.358 |
|
| 2012 |
Moynihan HA, Derrick I, Broadbear JH, Greedy BM, Aceto MD, Harris LS, Purington LC, Thomas MP, Woods JH, Traynor JR, Husbands SM, Lewis JW. Fumaroylamino-4,5-epoxymorphinans and related opioids with irreversible μ opioid receptor antagonist effects. Journal of Medicinal Chemistry. 55: 9868-74. PMID 23043264 DOI: 10.1021/jm301096s |
0.329 |
|
| 2012 |
Wise LE, Premaratne ID, Gamage TF, Lichtman AH, Hughes LD, Harris LS, Aceto MD. l-theanine attenuates abstinence signs in morphine-dependent rhesus monkeys and elicits anxiolytic-like activity in mice. Pharmacology, Biochemistry, and Behavior. 103: 245-52. PMID 22935630 DOI: 10.1016/J.Pbb.2012.08.008 |
0.346 |
|
| 2011 |
Follia V, Aceto MD, Harris LS, Coop A, Schmidhammer H, Spetea M. Introduction of a 6-cyano group in 14-oxygenated N-methylmorphinans influences in vitro and in vivo pharmacological activities Bmc Pharmacology. 11: A26. DOI: 10.1186/1471-2210-11-S2-A26 |
0.357 |
|
| 2009 |
Kwilasz AJ, Harris LS, Vann RE. Removal of continuous nicotine infusion produces somatic but not behavioral signs of withdrawal in mice. Pharmacology, Biochemistry, and Behavior. 94: 114-8. PMID 19660491 DOI: 10.1016/J.Pbb.2009.07.015 |
0.3 |
|
| 2009 |
Cami-Kobeci G, Neal AP, Bradbury FA, Purington LC, Aceto MD, Harris LS, Lewis JW, Traynor JR, Husbands SM. Mixed kappa/mu opioid receptor agonists: the 6 beta-naltrexamines. Journal of Medicinal Chemistry. 52: 1546-52. PMID 19253970 DOI: 10.1021/Jm8015552 |
0.336 |
|
| 2008 |
Metcalf MD, Aceto MD, Harris LS, Woods JH, Traynor JR, Coop A, May EL. The influence of esters and carboxylic acids as the N-substituent of opioids. Part 1: Benzomorphans. Bioorganic & Medicinal Chemistry. 16: 869-73. PMID 17962026 DOI: 10.1016/j.bmc.2007.10.030 |
0.355 |
|
| 2007 |
Hiebel AC, Lee YS, Bilsky E, Giuvelis D, Deschamps JR, Parrish DA, Aceto MD, May EL, Harris LS, Coop A, Dersch CM, Partilla JS, Rothman RB, Cheng K, Jacobson AE, et al. Probes for narcotic receptor mediated phenomena. 34. Synthesis and structure-activity relationships of a potent mu-agonist delta-antagonist and an exceedingly potent antinociceptive in the enantiomeric C9-substituted 5-(3-hydroxyphenyl)-N-phenylethylmorphan series. Journal of Medicinal Chemistry. 50: 3765-76. PMID 17625813 DOI: 10.1021/Jm061325E |
0.307 |
|
| 2007 |
Naidu PS, Lichtman AH, Archer CC, May EL, Harris LS, Aceto MD. NIH 11082 produces anti-depressant-like activity in the mouse tail-suspension test through a delta-opioid receptor mechanism of action. European Journal of Pharmacology. 566: 132-6. PMID 17459369 DOI: 10.1016/J.Ejphar.2007.03.031 |
0.35 |
|
| 2007 |
Aceto MD, May EL, Harris LS, Bowman ER, Cook CD. Pharmacological studies with a nonpeptidic, delta-opioid (-)-(1R,5R,9R)-5,9-dimethyl-2'-hydroxy-2-(6-hydroxyhexyl)-6,7-benzomorphan hydrochloride ((-)-NIH 11082). European Journal of Pharmacology. 566: 88-93. PMID 17434480 DOI: 10.1016/j.ejphar.2007.03.008 |
0.374 |
|
| 2007 |
Cheng K, Kim IJ, Lee MJ, Adah SA, Raymond TJ, Bilsky EJ, Aceto MD, May EL, Harris LS, Coop A, Dersch CM, Rothman RB, Jacobson AE, Rice KC. Opioid ligands with mixed properties from substituted enantiomeric N-phenethyl-5-phenylmorphans. Synthesis of a micro-agonist delta-antagonist and delta-inverse agonists. Organic & Biomolecular Chemistry. 5: 1177-90. PMID 17406716 DOI: 10.1039/B618875C |
0.36 |
|
| 2005 |
Carroll FI, Harris LS, Aceto MD. Effects of JDTic, a selective kappa-opioid receptor antagonist, on the development and expression of physical dependence on morphine using a rat continuous-infusion model. European Journal of Pharmacology. 524: 89-94. PMID 16236279 DOI: 10.1016/j.ejphar.2005.09.013 |
0.352 |
|
| 2005 |
Spetea M, Greiner E, Aceto MD, Harris LS, Coop A, Schmidhammer H. Effect of a 6-cyano substituent in 14-oxygenated N-methylmorphinans on opioid receptor binding and antinociceptive potency. Journal of Medicinal Chemistry. 48: 5052-5. PMID 16033285 DOI: 10.1021/jm0580205 |
0.374 |
|
| 2004 |
Carroll I, Thomas JB, Dykstra LA, Granger AL, Allen RM, Howard JL, Pollard GT, Aceto MD, Harris LS. Pharmacological properties of JDTic: a novel kappa-opioid receptor antagonist. European Journal of Pharmacology. 501: 111-9. PMID 15464069 DOI: 10.1016/j.ejphar.2004.08.028 |
0.38 |
|
| 2004 |
Spetea M, Schüllner F, Moisa RC, Berzetei-Gurske IP, Schraml B, Dörfler C, Aceto MD, Harris LS, Coop A, Schmidhammer H. Synthesis and biological evaluation of 14-alkoxymorphinans. 21. Novel 4-alkoxy and 14-phenylpropoxy derivatives of the mu opioid receptor antagonist cyprodime. Journal of Medicinal Chemistry. 47: 3242-7. PMID 15163203 DOI: 10.1021/jm031126k |
0.363 |
|
| 2003 |
Schütz J, Spetea M, Koch M, Aceto MD, Harris LS, Coop A, Schmidhammer H. Synthesis and biological evaluation of 14-alkoxymorphinans. 20. 14-phenylpropoxymetopon: an extremely powerful analgesic. Journal of Medicinal Chemistry. 46: 4182-7. PMID 12954070 DOI: 10.1021/jm030878b |
0.363 |
|
| 2003 |
Greiner E, Spetea M, Krassnig R, Schüllner F, Aceto M, Harris LS, Traynor JR, Woods JH, Coop A, Schmidhammer H. Synthesis and biological evaluation of 14-alkoxymorphinans. 18. N-substituted 14-phenylpropyloxymorphinan-6-ones with unanticipated agonist properties: extending the scope of common structure-activity relationships. Journal of Medicinal Chemistry. 46: 1758-63. PMID 12699394 DOI: 10.1021/jm021118o |
0.369 |
|
| 2003 |
May EL, Coop A, Woods JH, Aceto MD, Bowman ER, Harris LS, Traynor JR. N-(trifluoromethyl)benzyl substituted N-normetazocines and N-norketobemidones. Bioorganic & Medicinal Chemistry. 11: 31-3. PMID 12467704 DOI: 10.1016/S0968-0896(02)00435-2 |
0.331 |
|
| 2001 |
Gerak LR, Woolverton WL, Nader MA, Patrick GA, Harris LS, Winger G, Woods JH, France CP. Behavioral effects of flunitrazepam: reinforcing and discriminative stimulus effects in rhesus monkeys and prevention of withdrawal signs in pentobarbital-dependent rats. Drug and Alcohol Dependence. 63: 39-49. PMID 11297830 DOI: 10.1016/S0376-8716(00)00189-7 |
0.322 |
|
| 2000 |
Coop A, Jacobson AE, Aceto MD, Harris LS, Traynor JR, Woods JH, Rice KC. N-Cyclohexylethyl-N-noroxymorphindole: a mu-opioid preferring analogue of naltrindole. Bioorganic & Medicinal Chemistry Letters. 10: 2449-51. PMID 11078198 DOI: 10.1016/S0960-894X(00)00479-0 |
0.317 |
|
| 2000 |
Aceto MD, Scates SM, Harris LS, Ji Z. Dihydroetorphine: physical dependence and stereotypy after continuous infusion in the rat. European Journal of Pharmacology. 387: 31-7. PMID 10633157 DOI: 10.1016/S0014-2999(99)00758-X |
0.342 |
|
| 1999 |
Aceto MD, Harris LS, Abood ME, Rice KC. Stereoselective mu- and delta-opioid receptor-related antinociception and binding with (+)-thebaine. European Journal of Pharmacology. 365: 143-7. PMID 9988096 DOI: 10.1016/S0014-2999(98)00862-0 |
0.368 |
|
| 1998 |
Martin TJ, Hairston CT, Lutz PO, Harris LS, Porreca F. Anti-allodynic actions of intravenous opioids in the nerve injured rat: potential utility of heroin and dihydroetorphine against neuropathic pain. European Journal of Pharmacology. 357: 25-32. PMID 9788770 DOI: 10.1016/S0014-2999(98)00531-7 |
0.38 |
|
| 1998 |
Husbands SM, Sadd J, Broadbear JH, Woods JH, Martin J, Traynor JR, Aceto MD, Bowman ER, Harris LS, Lewis JW. 3-Alkyl ethers of clocinnamox: delayed long-term mu-antagonists with variable mu efficacy. Journal of Medicinal Chemistry. 41: 3493-8. PMID 9719602 DOI: 10.1021/Jm9810248 |
0.377 |
|
| 1997 |
Aceto MD, Harris LS, Bowman ER. Etorphines: mu-opioid receptor-selective antinociception and low physical dependence capacity. European Journal of Pharmacology. 338: 215-23. PMID 9424015 DOI: 10.1016/S0014-2999(97)81924-3 |
0.373 |
|
| 1997 |
Beardsley PM, Harris LS. Evaluation of the discriminative stimulus and reinforcing effects of dihydroetorphine. Drug and Alcohol Dependence. 48: 77-84. PMID 9363406 DOI: 10.1016/S0376-8716(97)00112-9 |
0.335 |
|
| 1997 |
Martin TJ, Kim SA, Harris LS, Smith JE. Potent reinforcing effects of dihydroetorphine in rats. European Journal of Pharmacology. 324: 141-5. PMID 9145764 DOI: 10.1016/S0014-2999(97)00074-5 |
0.383 |
|
| 1996 |
Beardsley PM, Balster RL, Harris LS. Evaluation of the discriminative stimulus and reinforcing effects of gammahydroxybutyrate (GHB). Psychopharmacology. 127: 315-22. PMID 8923566 DOI: 10.1007/s002130050092 |
0.335 |
|
| 1995 |
Borzelleca JF, Egle JL, Harris LS, Belleville JA. Toxicological evaluation of mu-agonists. Part II: Assessment of toxicity following 30 days of repeated oral dosing of male and female rats with levo-alpha-noracetylmethadol HCl (NorLAAM). Journal of Applied Toxicology : Jat. 15: 339-55. PMID 8666717 DOI: 10.1002/jat.2550150503 |
0.342 |
|
| 1995 |
Abood ME, Noel MA, Carter RC, Harris LS. Evaluation of a series of N-alkyl benzomorphans in cell lines expressing transfected delta- and mu-opioid receptors. Biochemical Pharmacology. 50: 851-9. PMID 7575648 DOI: 10.1016/0006-2952(95)02007-Y |
0.353 |
|
| 1994 |
LeVier DG, McCay JA, Stern ML, Harris LS, Page D, Brown RD, Musgrove DL, Butterworth LF, White KL, Munson AE. Immunotoxicological profile of morphine sulfate in B6C3F1 female mice. Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology. 22: 525-42. PMID 8056200 DOI: 10.1093/toxsci/22.4.525 |
0.366 |
|
| 1994 |
May EL, Aceto MD, Bowman ER, Bentley C, Martin BR, Harris LS, Medzihradsky F, Mattson MV, Jacobson AE. Antipodal alpha-N-(methyl through decyl)-N-normetazocines (5,9 alpha-dimethyl-2'-hydroxy-6,7-benzomorphans): in vitro and in vivo properties. Journal of Medicinal Chemistry. 37: 3408-18. PMID 7932569 DOI: 10.1021/Jm00046A026 |
0.527 |
|
| 1994 |
Woolverton WL, Massey BW, Winger G, Patrick GA, Harris LS. Evaluation of the abuse liability of aminorex. Drug and Alcohol Dependence. 36: 187-92. PMID 7889809 DOI: 10.1016/0376-8716(94)90144-9 |
0.32 |
|
| 1992 |
Mansbach RS, Gold LH, Harris LS. The acoustic startle response as a measure of behavioral dependence in rats. Psychopharmacology. 108: 40-6. PMID 1410145 DOI: 10.1007/BF02245283 |
0.364 |
|
| 1991 |
Iorio MA, Frigeni V, Bowman ER, Harris LS, May EL, Aceto MD. Common stereospecificity of opioid and dopamine systems for N-butyrophenone prodine-like compounds. Journal of Medicinal Chemistry. 34: 194-7. PMID 1671414 DOI: 10.1021/Jm00105A029 |
0.349 |
|
| 1990 |
Mansbach RS, Sannerud CA, Griffiths RR, Balster RL, Harris LS. Intravenous self-administration of 4-methylaminorex in primates. Drug and Alcohol Dependence. 26: 137-44. PMID 2242714 DOI: 10.1016/0376-8716(90)90120-4 |
0.316 |
|
| 1989 |
Knisely JS, Beardsley PM, Aceto MD, Balster RL, Harris LS. Assessment of the abuse potential of acetorphan, an enkephalinase inhibitor. Drug and Alcohol Dependence. 23: 143-51. PMID 2702924 DOI: 10.1016/0376-8716(89)90020-3 |
0.377 |
|
| 1987 |
Toro-Goyco E, Zenk PC, Estrada U, Kachur JF, Harris LS. Synthesis and pharmacologic properties of 6-succinylcodeine. Pharmacological Research Communications. 19: 527-35. PMID 3432320 DOI: 10.1016/0031-6989(87)90090-7 |
0.311 |
|
| 1987 |
Jacobson AE, Rice KC, Burke TR, Lupinacci L, Mattson MV, Aceto MD, Harris LS. 2,5-Dimethyl-2'-hydroxy-9 alpha- and 9 beta-(3-methylbutyl)-6,7-benzomorphans and N-substituted compounds in the 9 alpha-(3-methylbutyl) series: chemistry, pharmacology, and biochemistry. Journal of Pharmaceutical Sciences. 76: 248-52. PMID 3035172 DOI: 10.1002/Jps.2600760315 |
0.349 |
|
| 1987 |
Awaya H, May EL, Aceto MD, Harris LS, Silverton JV, Rice KC, Mattson MV, Jacobson AE. Hexahydro-1H-1-pyrindines from acid rearrangement of 9-alkylidene-5-(m-methoxyphenyl)-2-methylmorphans. A new structural type of narcotic antagonists. Journal of Medicinal Chemistry. 30: 947-50. PMID 3033248 DOI: 10.1021/Jm00388A037 |
0.316 |
|
| 1987 |
Harris LS. Pharmacological characteristics of agonist-antagonist analgesics. Drug and Alcohol Dependence. 20: 293-301. PMID 2894285 DOI: 10.1016/0376-8716(87)90003-2 |
0.341 |
|
| 1986 |
Lessor RA, Bajwa BS, Rice KC, Jacobson AE, Streaty RA, Klee WA, Smith CB, Aceto MD, May EL, Harris LS. Probes for narcotic receptor mediated phenomena. 13. Potential irreversible narcotic antagonist-based ligands derived from 6,14-endo-ethenotetrahydronororipavine with 7-(methoxyfumaroyl)amino, (bromoacetyl)amino, or isothiocyanate electrophiles: chemistry, biochemistry, and pharmacology. Journal of Medicinal Chemistry. 29: 2136-41. PMID 3023609 DOI: 10.1021/Jm00161A002 |
0.385 |
|
| 1986 |
Mokler DJ, Nelson BD, Harris LS, Rosecrans JA. The role of benzodiazepine receptors in the discriminative stimulus properties of delta-9-tetrahydrocannabinol. Life Sciences. 38: 1581-9. PMID 3010019 DOI: 10.1016/0024-3205(86)90497-2 |
0.317 |
|
| 1985 |
Aceto MD, Harris LS, Woods JH, Katz JL, Smith CB, Medzihradsky F, Jacobson AE, Shiotani S. Pharmacological actions of the racemic and the enantiomeric 1,4-dimethyl-10-hydroxy-2,3,4,5,6,7-hexahydro-1,6-methano-1H-4-benz azo nines (C-homobenzomorphans). Japanese Journal of Pharmacology. 39: 7-19. PMID 4068392 DOI: 10.1254/Jjp.39.7 |
0.416 |
|
| 1985 |
Harris LS, May EL. Historical introduction and review of chemistry. Drug and Alcohol Dependence. 14: 227-32. PMID 3888575 DOI: 10.1016/0376-8716(85)90058-4 |
0.347 |
|
| 1985 |
Landauer MR, Balster RL, Harris LS. Attenuation of cyclophosphamide-induced taste aversions in mice by prochlorperazine, delta 9-tetrahydrocannabinol, nabilone and levonantradol. Pharmacology, Biochemistry, and Behavior. 23: 259-66. PMID 2997807 DOI: 10.1016/0091-3057(85)90567-2 |
0.328 |
|
| 1985 |
Jorapur VS, Khalil ZH, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Hashish: synthesis and central nervous system activity of some novel analogues of cannabidiol and oxepin derivatives of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 28: 783-7. PMID 2989518 DOI: 10.1021/Jm00383A016 |
0.702 |
|
| 1985 |
Aceto MD, Harris LS. Cynomolgus monkeys and morphine tolerance and dependence. Drug and Alcohol Dependence. 15: 15-8. PMID 2410213 DOI: 10.1016/0376-8716(85)90025-0 |
0.346 |
|
| 1985 |
Jorapur VS, Khalil ZH, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Hashish: Synthesis And Central Nervous System Activity Of Some Novel Analogs Of Cannabidiol And Oxepin Derivatives Of Δ9-Tetrahydrocannabinol Cheminform. 16. DOI: 10.1002/Chin.198544344 |
0.314 |
|
| 1984 |
Awaya H, May EL, Aceto MD, Merz H, Rogers ME, Harris LS. Racemic and optically active 2,9-dimethyl-5-(m-hydroxyphenyl)morphans and pharmacological comparison with the 9-demethyl homologues. Journal of Medicinal Chemistry. 27: 536-9. PMID 6708055 DOI: 10.1021/Jm00370A019 |
0.344 |
|
| 1984 |
Martin BR, Reynolds ML, Harris LS, Toro-Goyco E. Binding of [3H]phenycyclidine to rat and human blood constituents. Biochemical Pharmacology. 33: 429-34. PMID 6704162 DOI: 10.1016/0006-2952(84)90236-3 |
0.439 |
|
| 1984 |
Robertson LR, Duffley RP, Razdan RK, Martin BR, Harris LS, Dewey WL. Synthesis and pharmacological activity of some 9-substituted delta 8-tetrahydrocannabinol analogues. Journal of Medicinal Chemistry. 27: 550-2. PMID 6323713 DOI: 10.1021/Jm00370A023 |
0.693 |
|
| 1984 |
Martin BR, Katzen JS, Woods JA, Tripathi HL, Harris LS, May EL. Stereoisomers of [3H]-N-allylnormetazocine bind to different sites in mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 231: 539-44. PMID 6094791 |
0.373 |
|
| 1984 |
Martin BR, Kallman MJ, Kaempf GF, Harris LS, Dewey WL, Razdan RK. Pharmacological potency of R- and S-3'-hydroxy-delta 9-tetrahydrocannabinol: additional structural requirement for cannabinoid activity. Pharmacology, Biochemistry, and Behavior. 21: 61-5. PMID 6087379 DOI: 10.1016/0091-3057(84)90131-X |
0.681 |
|
| 1984 |
ROBERTSON LR, DUFFLEY RP, RAZDAN RK, MARTIN BR, HARRIS LS, DEWEY WL. ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL ACTIVITY OF SOME 9-SUBSTITUTED Δ8-TETRAHYDROCANNABINOL (THC) ANALOGS Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198438203 |
0.632 |
|
| 1983 |
Atkinson ER, McRitchie-Ticknor DD, Harris LS, Archer S, Aceto MD, Pearl J, Luduena FP. Parasympatholytic (anticholinergic) esters of the isomeric 2-tropanols. 2. Non-glycolates. Journal of Medicinal Chemistry. 26: 1772-5. PMID 6644747 DOI: 10.1002/Chin.197816233 |
0.307 |
|
| 1983 |
Harris LS, Aceto MD, Balster RL, Martin BR. Progress report: Medical College of Virginia--sigma agonists. Nida Research Monograph. 43: 79-84. PMID 6308455 |
0.326 |
|
| 1983 |
HANDRICK GR, DUFFLEY RP, LAMBERT G, MURPHY JG, DALZELL HC, HOWES JF, RAZDAN RK, MARTIN BR, HARRIS LS, DEWEY WL. ChemInform Abstract: 3′-HYDROXY- AND (.+-.)-3′,11-DIHYDROXY-Δ9-TETRAHYDROCANNABINOL: (THC) BIOLOGICALLY ACTIVE METABOLITES OF Δ9-TETRAHYDROCANNABINOL Chemischer Informationsdienst. 14. DOI: 10.1002/CHIN.198322251 |
0.616 |
|
| 1982 |
Handrick GR, Duffley RP, Lambert G, Murphy JG, Dalzell HC, Howes JF, Razdan RK, Martin BR, Harris LS, Dewey WL. 3'-Hydroxy- and (+/-)-3',11-dihydroxy-delta 9-tetrahydrocannabinol: biologically active metabolites of delta 9-tetrahydrocannabinol. Journal of Medicinal Chemistry. 25: 1447-50. PMID 6296389 |
0.676 |
|
| 1981 |
Vincek WC, Martin BR, Aceto MD, Tripathi HL, May EL, Harris LS. Synthesis of 4,4-ditritio-(+)-nicotine: comparative binding and distribution studies with natural enantiomer. Journal of Pharmaceutical Sciences. 70: 1292-3. PMID 7299682 DOI: 10.1002/JPS.2600701131 |
0.451 |
|
| 1981 |
Aceto MD, Harris LS, Dewey WL, May EL. Annual report: dependence studies of new compounds in the rhesus monkey (1980). Nida Research Monograph. 34: 297-326. PMID 6783944 |
0.573 |
|
| 1981 |
Martin BR, Balster RL, Razdan RK, Harris LS, Dewey WL. Behavioral comparisons of the stereoisomers of tetrahydrocannabinols. Life Sciences. 29: 565-74. PMID 6268916 DOI: 10.1016/0024-3205(81)90434-3 |
0.675 |
|
| 1980 |
Laychock SG, Johnson DN, Harris LS. PGD2 effects on rodent behavior and EEG patterns in cats. Pharmacology, Biochemistry, and Behavior. 12: 747-54. PMID 7393969 DOI: 10.1016/0091-3057(80)90161-6 |
0.338 |
|
| 1980 |
Man M, Harris LS, Woods LA, Martin BR. Isotope dilution technique for the estimation of l-alpha-[2-3H]-acetylmethadol and its metabolites in biological samples. Pharmacology. 20: 130-6. PMID 6992151 |
0.329 |
|
| 1980 |
Alozie SO, Martin BR, Harris LS, Dewey WL. 3H-delta 9-Tetrahydrocannabinol, 3H-cannabinol and 3H-cannabidiol: penetration and regional distribution in rat brain. Pharmacology, Biochemistry, and Behavior. 12: 217-21. PMID 6246544 DOI: 10.1016/0091-3057(80)90359-7 |
0.664 |
|
| 1980 |
Man M, Alozie SO, Woods LA, Martin BR, Harris LS. Distribution of l-alpha-[2-3H]acetylmethadol and its metabolites in maternal and fetal rat tissues. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 8: 55-9. PMID 6103787 |
0.34 |
|
| 1979 |
Aceto MD, Martin BR, Uwaydah IM, May EL, Harris LS, Izazola-Conde C, Dewey WL, Bradshaw TJ, Vincek WC. Optically pure (+)-nicotine from (+/-)-nicotine and biological comparisons with (-)-nicotine. Journal of Medicinal Chemistry. 22: 174-7. PMID 423195 DOI: 10.1021/JM00188A009 |
0.647 |
|
| 1979 |
Aceto MD, Harris LS, Dewey WL, May EL. Annual report: dependence studies on new compounds in the rhesus monkey (1979). Nida Research Monograph. 27: 330-50. PMID 121356 |
0.573 |
|
| 1979 |
Rosecrans JA, Campbell OL, Dewey WL, Harris LS. Discriminative stimulus and neurochemical mechanism of cathinone: a preliminary study. Nida Research Monograph. 27: 328-9. PMID 121355 |
0.534 |
|
| 1979 |
Carney JM, Balster RL, Martin BR, Harris LS. Effects of systemic and intraventricular administration of cannabinoids on schedule-controlled responding in the squirrel monkey. The Journal of Pharmacology and Experimental Therapeutics. 210: 399-404. PMID 113528 |
0.421 |
|
| 1979 |
Toro-Goyco E, Martin BR, Harris LS. The binding of LAAM and its metabolites to blood constituents. Nida Research Monograph. 27: 54-60. PMID 95037 |
0.307 |
|
| 1978 |
McConnell WR, Dewey WL, Harris LS, Borzelleca JF. A study of the effect of delta 9-tetrahydrocannabinol (delta 9-THC) on mammalian salivary flow. The Journal of Pharmacology and Experimental Therapeutics. 206: 567-73. PMID 702321 |
0.558 |
|
| 1978 |
Harris LS, Carchman RA, Martin BR. Evidence for the existence of specific cannabinoid binding sites. Life Sciences. 22: 1131-7. PMID 661500 DOI: 10.1016/0024-3205(78)90082-6 |
0.418 |
|
| 1978 |
Patrick GA, Dewey WL, Huger FP, Daves ED, Harris LS. Disposition of morphine in chronically infused rats: relationship to antinociception and tolerance. The Journal of Pharmacology and Experimental Therapeutics. 205: 556-62. PMID 660529 |
0.633 |
|
| 1978 |
Aceto MD, Carchman RA, Harris LS, Flora RE. Caffeine elicited withdrawal signs in morphine-dependent rhesus monkeys. European Journal of Pharmacology. 50: 203-7. PMID 211041 DOI: 10.1016/0014-2999(78)90352-7 |
0.37 |
|
| 1978 |
Martin BR, Montgomery J, Dewey WL, Harris LS. Alterations in the pharmacokinetics of 3H-delta9-tetrahydrocannabinol in mice by bacterial endotoxin. Drug Metabolism and Disposition: the Biological Fate of Chemicals. 6: 282-7. PMID 26549 |
0.667 |
|
| 1977 |
Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol distribution in pregnant dogs and their fetuses. Research Communications in Chemical Pathology and Pharmacology. 17: 457-70. PMID 897339 |
0.632 |
|
| 1977 |
Adams MD, Earnhardt JT, Martin BR, Harris LS, Dewey WL, Razdan RK. A cannabinoid with cardiovascular activity but no overt behavioral effects. Experientia. 33: 1204-5. PMID 891878 DOI: 10.1007/Bf01922330 |
0.675 |
|
| 1977 |
Bloom AS, Dewey WL, Harris LS, Brosius KK. 9-nor-9beta-hydroxyhexahydrocannabinol, a cannabinoid with potent antinociceptive activity: comparisons with morphine. The Journal of Pharmacology and Experimental Therapeutics. 200: 263-70. PMID 839438 |
0.612 |
|
| 1977 |
Atkinson ER, McRitchie DD, Shoer LF, Harris LS, Archer S, Aceto MD, Pearl J, Luduena FP. Parasympatholytic (anticholinergic) esters of the isomeric 2-tropanols. 1. Glycolates. Journal of Medicinal Chemistry. 20: 1612-7. PMID 592326 DOI: 10.1021/Jm00222A015 |
0.33 |
|
| 1977 |
Bradley SG, Munson AE, Dewey WL, Harris LS. Enhanced susceptibility of mice to combinations of delta 9-tetrahydrocannabinol and live or killed gram-negative bacteria. Infection and Immunity. 17: 325-9. PMID 330405 |
0.571 |
|
| 1977 |
Uwaydah IM, May EL, Harris LS. Synthesis and pharmacological activity of some N-alkyl-substituted 9alpha-ethyl-2'-hydroxy-5-methyl-6,7-benzomorphans. Journal of Medicinal Chemistry. 20: 1374-7. PMID 21291 DOI: 10.1021/Jm00221A004 |
0.353 |
|
| 1976 |
Martin BR, Dewey WL, Harris LS, Beckner JS. 3H-delta9-tetrahydrocannabinol tissue and subcellular distribution in the central nervous system and tissue distribution in peripheral organs of tolerant and nontolerant dogs. The Journal of Pharmacology and Experimental Therapeutics. 196: 128-44. PMID 1246007 |
0.644 |
|
| 1976 |
Atkinson ER, Battista SP, Ary IE, Richardson DG, Harris LS, Dewey WL. Derivatives of apomorphine and of other N-substituted norapomorphines. Journal of Pharmaceutical Sciences. 65: 1682-5. PMID 994002 DOI: 10.1002/Jps.2600651129 |
0.626 |
|
| 1976 |
Day AR, Luján M, Dewey WL, Harris LS, Radding JA, Freer RJ. Structure-activity relationships of enkephalins in the stimulated guinea pig ileum. Research Communications in Chemical Pathology and Pharmacology. 14: 597-603. PMID 959662 |
0.59 |
|
| 1976 |
Johnson KM, Dewey WL, Harris LS. Some structural requirements for inhibition of high-affinity synaptosomal serotonin uptake by cannabinoids. Molecular Pharmacology. 12: 345-52. PMID 934055 |
0.548 |
|
| 1976 |
Pars HG, Granchelli FE, Razdan RK, Keller JK, Teiger DG, Rosenberg FJ, Harris LS. Drugs derived from cannabinoids. 1. Nitrogen analogs, benzopyranopyridines and benzopyranopyrroles. Journal of Medicinal Chemistry. 19: 445-54. PMID 817019 DOI: 10.1021/Jm00226A001 |
0.332 |
|
| 1976 |
Bloom AS, Dewey WL, Harris LS, Brosius KK. The correlation between antinociceptive activity of narcotics and their antagonists as measured in the mouse tail-flick test and increased synthesis of brain catecholamines. The Journal of Pharmacology and Experimental Therapeutics. 198: 33-41. PMID 6793 |
0.65 |
|
| 1976 |
Adams MD, Earnhardt JT, Dewey WL, Harris LS. Vasoconstrictor actions of delta8- and delta9-tetrahydrocannabinol in the rat. The Journal of Pharmacology and Experimental Therapeutics. 196: 649-56. PMID 4606 |
0.611 |
|
| 1976 |
Pedigo NW, Dewey WL, Harris LS. Pharmacology Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice Pain. 2: 86. DOI: 10.1016/0304-3959(76)90055-5 |
0.612 |
|
| 1975 |
Martin BR, Dewey WL, Harris LS, Beckner J. Marihuana-like activity of new synthetic tetrahydrocannabinols. Pharmacology, Biochemistry, and Behavior. 3: 849-53. PMID 1208625 DOI: 10.1016/0091-3057(75)90116-1 |
0.71 |
|
| 1975 |
Munson AE, Harris LS, Friedman MA, Dewey WL, Carchman RA. Antineoplastic activity of cannabinoids. Journal of the National Cancer Institute. 55: 597-602. PMID 1159836 |
0.598 |
|
| 1975 |
Patrick GA, Dewey WL, Spaulding TC, Harris LS. Relationship of brain morphine levels to analgesic activity in acutely treated mice and rats and in pellet implanted mice. The Journal of Pharmacology and Experimental Therapeutics. 193: 876-83. PMID 1151736 |
0.628 |
|
| 1975 |
Pedigo NW, Dewey WL, Harris LS. Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice. The Journal of Pharmacology and Experimental Therapeutics. 193: 845-52. PMID 1151733 |
0.649 |
|
| 1975 |
Dewey WL, Cocolas G, Daves E, Harris LS. Stereospecificity of intraventricularly administered acetylmethylcholine antinociception. Life Sciences. 17: 9-10. PMID 1143014 DOI: 10.1016/0024-3205(75)90224-6 |
0.668 |
|
| 1975 |
Harris RA, Harris LS, Dunn A. Effect of narcotic drugs on ribonucleic acid and nucleotide metabolism in mouse brain. The Journal of Pharmacology and Experimental Therapeutics. 192: 280-7. PMID 1117416 |
0.387 |
|
| 1975 |
Chipkin RE, Dewey WL, Harris LS, Lowenthal W. Effect of propranolol on antinociceptive and withdrawal characteristics of morphine. Pharmacology, Biochemistry, and Behavior. 3: 843-7. PMID 1800 DOI: 10.1016/0091-3057(75)90115-X |
0.665 |
|
| 1975 |
Martin BR, Dewey WL, Harris LS, Beckner J, Wilson RS, May EL. Marihuana-like activity of new synthetic tetrahydrocannabinols Pharmacology, Biochemistry and Behavior. 3: 849-853. DOI: 10.1016/0091-3057(75)90116-1 |
0.566 |
|
| 1974 |
Kosersky DS, Harris RA, Harris LS. Naloxone-precipitated jumping activity in mice following the acute administration of morphine. European Journal of Pharmacology. 26: 122-4. PMID 4857602 DOI: 10.1016/0014-2999(74)90084-3 |
0.492 |
|
| 1974 |
Dykstra LA, McMillan DE, Harris LS. Antagonism of morphine by long acting narcotic antagonists. Psychopharmacologia. 39: 151-62. PMID 4476081 DOI: 10.1007/Bf00440845 |
0.378 |
|
| 1974 |
Harris RA, Dunn A, Harris LS. Effects of acute and chronic morphine administration on the incorporation of (3H)-lysine into mouse brain and liver proteins. Research Communications in Chemical Pathology and Pharmacology. 9: 299-306. PMID 4438835 |
0.358 |
|
| 1974 |
Abel EL, McMillan DE, Harris LS. δ9-Tetrahydrocannabinol: Effects of route of administration on onset and duration of activity and tolerance development Psychopharmacologia. 35: 29-38. DOI: 10.1007/Bf00421563 |
0.322 |
|
| 1973 |
Kosersky DS, Dewey WL, Harris LS. Antipyretic, analgesic and anti-inflammatory effects of delta 9-tetrahydrocannabinol in the rat. European Journal of Pharmacology. 24: 1-7. PMID 4756165 DOI: 10.1016/0014-2999(73)90107-6 |
0.645 |
|
| 1973 |
Chau TT, Dewey WL, Harris LS. Mechanism of the synergistic lethality between pentazocine and vasopressin in the rat. The Journal of Pharmacology and Experimental Therapeutics. 186: 288-96. PMID 4719781 |
0.561 |
|
| 1973 |
Turk RF, Dewey WL, Harris LS. Excretion of trans- 9 -tetrahydrocannabinol and its metabolites in intact and bile duct-cannulated rats. Journal of Pharmaceutical Sciences. 62: 737-40. PMID 4705677 DOI: 10.1002/Jps.2600620506 |
0.609 |
|
| 1973 |
Dewey WL, McMillan DE, Harris LS, Turk RF. Distribution of radioactivity in brain of tolerant and nontolerant pigeons treated with 3 H- 9 -tetrahydrocannabinol. Biochemical Pharmacology. 22: 399-405. PMID 4687135 DOI: 10.1016/0006-2952(73)90420-6 |
0.62 |
|
| 1973 |
McMillan DE, Dewey WL, Turk RF, Harris LS, McNeil JH. Blood levels of 3 H- 9 -tetrahydrocannabinol and its metabolites in tolerant and nontolerant pigeons. Biochemical Pharmacology. 22: 383-97. PMID 4687134 DOI: 10.1016/0006-2952(73)90419-X |
0.622 |
|
| 1972 |
Dewey WL, Harris LS, Kennedy JS. Some pharmacological and toxicological effects of 1-trans- 8 and 1-trans- 9 -tetrahydrocannabinol in laboratory rodents. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 196: 133-45. PMID 5059359 |
0.578 |
|
| 1972 |
McMillan DE, Ford RD, Frankenheim JM, Harris RA, Harris LS. Tolerance to active constituents of marihuana. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 198: 132-44. PMID 5053235 |
0.333 |
|
| 1972 |
Dewey WL, Jenkins J, O'Rourke T, Harris LS. The effects of chronic administration of trans- 9 -tetrahydrocannabinol on behavior and the cardiovascular system of dogs. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 198: 118-31. PMID 5053234 |
0.574 |
|
| 1972 |
Zitko BA, Howes JF, Razdan RK, Dalzell BC, Dalzell HC, Sheehan JC, Pars HG, Dewey WL, Harris LS. Water-soluble derivatives of 1 -tetrahydrocannabinol. Science (New York, N.Y.). 177: 442-4. PMID 5043146 DOI: 10.1126/science.177.4047.442 |
0.603 |
|
| 1972 |
Spaulding TC, Ford RD, Dewey WL, McMillan DE, Harris LS. Some pharmacological effects of phenitrone and its interaction with 9 -THC. European Journal of Pharmacology. 19: 310-7. PMID 4640854 DOI: 10.1016/0014-2999(72)90096-9 |
0.668 |
|
| 1972 |
ZITKO BA, HOWES JF, RAZDAN RK, DALZELL BC, DALZELL HC, SHEEHAN JC, PARS HG, DEWEY WL, HARRIS LS. ChemInform Abstract: WASSERLOESLICHE DERIVATE VON DELTA(1)-TETRAHYDROCANNABINOL Chemischer Informationsdienst. 3: no-no. DOI: 10.1002/chin.197250288 |
0.614 |
|
| 1971 |
McMillan DE, Dewey WL, Harris LS. CHARACTERISTICS OF TETRAHYDROCANNABINOL TOLERANCE Annals of the New York Academy of Sciences. 191: 83-99. DOI: 10.1111/J.1749-6632.1971.Tb13990.X |
0.592 |
|
| 1970 |
McMillan DE, Harris LS, Frankenheim JM, Kennedy JS. l-Dgr9-trans-Tetrahydrocannabinol in Pigeons: Tolerance to the Behavioral Effects. Science (New York, N.Y.). 169: 501-3. PMID 17739012 DOI: 10.1126/Science.169.3944.501 |
0.308 |
|
| 1970 |
Howes JF, Harris LS, Dewey WL. The effect of morphine, nalorphine, naloxone, pentazocine, cyclazocine and oxotremorine on the synthesis and release of acetylcholine by mouse cerebral cortex slices in vitro. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 184: 267-76. PMID 5453231 |
0.596 |
|
| 1970 |
Dewey WL, Harris LS, Howes JF, Kennedy JS, Granchelli FE, Pars HG, Razdan RK. Pharmacology of some marijuana constituents and 2 heterocyclic analogues. Nature. 226: 1265-7. PMID 5422606 DOI: 10.1038/2261265A0 |
0.62 |
|
| 1970 |
Dewey WL, Harris LS, Howes JF, Nuite JA. The effect of various neurohumoral modulators on the activity of morphine and the narcotic antagonists in the tail-flick and phenylquinone tests. The Journal of Pharmacology and Experimental Therapeutics. 175: 435-42. PMID 4394803 |
0.621 |
|
| 1970 |
Dewey WL, Peng TC, Harris LS. The effect of 1-trans-delta 9-tetrahydrocannabinol on the hypothalamo-hypophyseal-adrenal axis of rats. European Journal of Pharmacology. 12: 382-4. PMID 4322071 DOI: 10.1016/0014-2999(70)90094-4 |
0.632 |
|
| 1969 |
Howes JF, Harris LS, Dewey WL, Voyda CA. Brain acetylcholine levels and inhibition of the tail-flick reflex in mice. The Journal of Pharmacology and Experimental Therapeutics. 169: 23-8. PMID 5804609 |
0.583 |
|
| 1969 |
Dewey WL, Harris LS, Howes JF, Kennedy JS, Nuite JA, Hayhurst V. The effects of narcotic-antagonist analgesics on rat brain cholinesterases. Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 182: 471-80. PMID 5371206 |
0.6 |
|
| 1969 |
Harris LS, Dewey WL, Howes JF, Kennedy JS, Pars H. Narcotic-antagonist analgesics: interactions with cholinergic systems. The Journal of Pharmacology and Experimental Therapeutics. 169: 17-22. PMID 4389919 |
0.556 |
|
| 1969 |
Dewey WL, Snyder JW, Harris LS, Howes JF. The effect of narcotics and narcotic antagonists on the tail-flick response in spinal mice. The Journal of Pharmacy and Pharmacology. 21: 548-50. PMID 4389723 DOI: 10.1111/J.2042-7158.1969.Tb08312.X |
0.613 |
|
| 1967 |
Harris LS, Pierson AK, Dembinski JR, Dewey WL. The pharmacology of (minus)-3-hydroxy-N-cyclopropylmethylmorphinan (cyclorphan). Archives Internationales De Pharmacodynamie Et De Thã©Rapie. 165: 112-26. PMID 4382141 |
0.55 |
|
| 1967 |
Harris LS, Dewey WL. Chapter 4. Analgetics–Strong and Weak Annual Reports in Medicinal Chemistry. 2: 33-43. DOI: 10.1016/S0065-7743(08)61501-8 |
0.334 |
|
| 1966 |
Harris LS, Pearl J, Aceto MD. Similarities in effects of barbiturates and mild tranquilizers on activity in mice Psychonomic Science. 4: 267-268. DOI: 10.3758/BF03342289 |
0.316 |
|
| 1964 |
HARRIS LS. NARCOTIC ANTAGONISTS IN THE BENZOMORPHAN SERIES. RESPIRATORY, CARDIOVASCULAR AND BEHAVIORAL EFFECTS IN DOGS. Naunyn-Schmiedebergs Archiv Fã¼R Experimentelle Pathologie Und Pharmakologie. 248: 426-36. PMID 14258615 DOI: 10.1007/BF00246889 |
0.346 |
|
| 1964 |
ARCHER S, ALBERTSON NF, HARRIS LS, PIERSON AK, BIRD JG. PENTAZOCINE. STRONG ANALGESICS AND ANALGESIC ANTAGONISTS IN THE BENZOMORPHAN SERIES. Journal of Medicinal Chemistry. 7: 123-7. PMID 14187360 DOI: 10.1021/Jm00332A001 |
0.353 |
|
| 1962 |
ARCHER S, ALBERTSON NF, HARRIS LS, PIERSON AK, BIRD JG, KEATS AS, TELFORD J, PAPADOPOULOS CN. Narcotic antagonists as analgesics. Science (New York, N.Y.). 137: 541-3. PMID 13862080 DOI: 10.1126/Science.137.3529.541 |
0.399 |
|
| 1961 |
HARRIS LS, UHLE FC. Enhancement of amphetamine stimulation and prolongation of barbiturate depression by a substituted pyridl 3,4-blindole derivative. The Journal of Pharmacology and Experimental Therapeutics. 132: 251-7. PMID 13711758 |
0.622 |
|
| 1960 |
HARRIS LS, UHLE FC. 4-Substituted indoles as antagonists to 5-hydroxytryptamine and to the veratrine response. The Journal of Pharmacology and Experimental Therapeutics. 128: 358-62. PMID 14399979 |
0.643 |
|
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