Year |
Citation |
Score |
2020 |
Flaherty E, Maniatis T. The role of clustered protocadherins in neurodevelopment and neuropsychiatric diseases. Current Opinion in Genetics & Development. 65: 144-150. PMID 32679536 DOI: 10.1016/j.gde.2020.05.041 |
0.348 |
|
2020 |
Gerbino V, Kaunga E, Ye J, Canzio D, O'Keeffe S, Rudnick ND, Guarnieri P, Lutz CM, Maniatis T. The Loss of TBK1 Kinase Activity in Motor Neurons or in All Cell Types Differentially Impacts ALS Disease Progression in SOD1 Mice. Neuron. PMID 32220666 DOI: 10.1016/J.Neuron.2020.03.005 |
0.354 |
|
2019 |
Ye J, Cheung J, Gerbino V, Ahlsén G, Zimanyi C, Hirsh D, Maniatis T. Effects of ALS-associated TANK binding kinase 1 mutations on protein-protein interactions and kinase activity. Proceedings of the National Academy of Sciences of the United States of America. PMID 31748271 DOI: 10.1073/pnas.1915732116 |
0.316 |
|
2019 |
Canzio D, Maniatis T. The generation of a protocadherin cell-surface recognition code for neural circuit assembly. Current Opinion in Neurobiology. 59: 213-220. PMID 31710891 DOI: 10.1016/J.Conb.2019.10.001 |
0.358 |
|
2019 |
Canzio D, Nwakeze CL, Horta A, Rajkumar SM, Coffey EL, Duffy EE, Duffié R, Monahan K, O'Keeffe S, Simon MD, Lomvardas S, Maniatis T. Antisense lncRNA Transcription Mediates DNA Demethylation to Drive Stochastic Protocadherin α Promoter Choice. Cell. PMID 30955885 DOI: 10.1016/J.Cell.2019.03.008 |
0.736 |
|
2019 |
Gelfman S, Dugger SA, Araujo Martins Moreno C, Ren Z, Wolock CJ, Shneider N, Phatnani H, Cirulli ET, Lasseigne BN, Harris T, Maniatis T, Rouleau G, Brown RH, Gitler AD, Myers RM, et al. A new approach for rare variation collapsing on functional protein domains implicates specific genic regions in ALS. Genome Research. PMID 30940688 DOI: 10.1101/Gr.243592.118 |
0.792 |
|
2018 |
Mountoufaris G, Canzio D, Nwakeze CL, Chen WV, Maniatis T. Writing, Reading, and Translating the Clustered Protocadherin Cell Surface Recognition Code for Neural Circuit Assembly. Annual Review of Cell and Developmental Biology. 34: 471-493. PMID 30296392 DOI: 10.1146/Annurev-Cellbio-100616-060701 |
0.566 |
|
2018 |
Yuan Y, Xie S, Darnell JC, Darnell AJ, Saito Y, Phatnani H, Murphy EA, Zhang C, Maniatis T, Darnell RB. Cell type-specific CLIP reveals that NOVA regulates cytoskeleton interactions in motoneurons. Genome Biology. 19: 117. PMID 30111345 DOI: 10.1186/S13059-018-1493-2 |
0.739 |
|
2017 |
Rudnick ND, Griffey CJ, Guarnieri P, Gerbino V, Wang X, Piersaint JA, Tapia JC, Rich MM, Maniatis T. Distinct roles for motor neuron autophagy early and late in the SOD1(G93A) mouse model of ALS. Proceedings of the National Academy of Sciences of the United States of America. PMID 28904095 DOI: 10.1073/pnas.1704294114 |
0.782 |
|
2017 |
Rizvi AH, Camara PG, Kandror EK, Roberts TJ, Schieren I, Maniatis T, Rabadan R. Single-cell topological RNA-seq analysis reveals insights into cellular differentiation and development. Nature Biotechnology. PMID 28459448 DOI: 10.1038/Nbt.3854 |
0.362 |
|
2017 |
Mountoufaris G, Chen WV, Hirabayashi Y, O'Keeffe S, Chevee M, Nwakeze CL, Polleux F, Maniatis T. Multicluster Pcdh diversity is required for mouse olfactory neural circuit assembly. Science (New York, N.Y.). 356: 411-414. PMID 28450637 DOI: 10.1126/Science.Aai8801 |
0.552 |
|
2017 |
Chen WV, Nwakeze CL, Denny CA, O'Keeffe S, Rieger MA, Mountoufaris G, Kirner A, Dougherty JD, Hen R, Wu Q, Maniatis T. Pcdhαc2 is required for axonal tiling and assembly of serotonergic circuitries in mice. Science (New York, N.Y.). 356: 406-411. PMID 28450636 DOI: 10.1126/Science.Aal3231 |
0.637 |
|
2016 |
Goodman KM, Rubinstein R, Thu CA, Mannepalli S, Bahna F, Ahlsén G, Rittenhouse C, Maniatis T, Honig B, Shapiro L. γ-Protocadherin structural diversity and functional implications. Elife. 5. PMID 27782885 DOI: 10.7554/Elife.20930 |
0.314 |
|
2016 |
Lomvardas S, Maniatis T. Histone and DNA Modifications as Regulators of Neuronal Development and Function. Cold Spring Harbor Perspectives in Biology. 8. PMID 27371659 DOI: 10.1101/cshperspect.a024208 |
0.326 |
|
2016 |
He J, Zhou R, Wu Z, Carrasco MA, Kurshan PT, Farley JE, Simon DJ, Wang G, Han B, Hao J, Heller E, Freeman MR, Shen K, Maniatis T, Tessier-Lavigne M, et al. Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species. Proceedings of the National Academy of Sciences of the United States of America. PMID 27162329 DOI: 10.1073/Pnas.1605707113 |
0.392 |
|
2016 |
Goodman KM, Rubinstein R, Thu CA, Bahna F, Mannepalli S, Ahlsén G, Rittenhouse C, Maniatis T, Honig B, Shapiro L. Structural Basis of Diverse Homophilic Recognition by Clustered α- and β-Protocadherins. Neuron. PMID 27161523 DOI: 10.1016/J.Neuron.2016.04.004 |
0.3 |
|
2015 |
Rubinstein R, Thu CA, Goodman KM, Wolcott HN, Bahna F, Mannepalli S, Ahlsen G, Chevee M, Halim A, Clausen H, Maniatis T, Shapiro L, Honig B. Molecular Logic of Neuronal Self-Recognition through Protocadherin Domain Interactions. Cell. 163: 629-42. PMID 26478182 DOI: 10.1016/J.Cell.2015.09.026 |
0.327 |
|
2015 |
Guo Y, Xu Q, Canzio D, Shou J, Li J, Gorkin DU, Jung I, Wu H, Zhai Y, Tang Y, Lu Y, Wu Y, Jia Z, Li W, Zhang MQ, ... ... Maniatis T, et al. CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function. Cell. 162: 900-10. PMID 26276636 DOI: 10.1016/J.Cell.2015.07.038 |
0.78 |
|
2015 |
Ye J, Beetz N, O'Keeffe S, Tapia JC, Macpherson L, Chen WV, Bassel-Duby R, Olson EN, Maniatis T. hnRNP U protein is required for normal pre-mRNA splicing and postnatal heart development and function. Proceedings of the National Academy of Sciences of the United States of America. 112: E3020-9. PMID 26039991 DOI: 10.1073/Pnas.1508461112 |
0.561 |
|
2015 |
Phatnani H, Maniatis T. Astrocytes in Neurodegenerative Disease. Cold Spring Harbor Perspectives in Biology. 7. PMID 25877220 DOI: 10.1101/cshperspect.a020628 |
0.625 |
|
2015 |
Cirulli ET, Lasseigne BN, Petrovski S, Sapp PC, Dion PA, Leblond CS, Couthouis J, Lu YF, Wang Q, Krueger BJ, Ren Z, Keebler J, Han Y, Levy SE, Boone BE, ... ... Maniatis T, et al. Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways. Science (New York, N.Y.). 347: 1436-41. PMID 25700176 DOI: 10.1126/Science.Aaa3650 |
0.749 |
|
2014 |
Zhang Y, Chen K, Sloan SA, Bennett ML, Scholze AR, O'Keeffe S, Phatnani HP, Guarnieri P, Caneda C, Ruderisch N, Deng S, Liddelow SA, Zhang C, Daneman R, Maniatis T, et al. An RNA-sequencing transcriptome and splicing database of glia, neurons, and vascular cells of the cerebral cortex. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 11929-47. PMID 25186741 DOI: 10.1523/Jneurosci.1860-14.2014 |
0.74 |
|
2014 |
Thu CA, Chen WV, Rubinstein R, Chevee M, Wolcott HN, Felsovalyi KO, Tapia JC, Shapiro L, Honig B, Maniatis T. Single-cell identity generated by combinatorial homophilic interactions between α, β, and γ protocadherins. Cell. 158: 1045-59. PMID 25171406 DOI: 10.1016/J.Cell.2014.07.012 |
0.574 |
|
2014 |
Nishimura AL, Shum C, Scotter EL, Abdelgany A, Sardone V, Wright J, Lee YB, Chen HJ, Bilican B, Carrasco M, Maniatis T, Chandran S, Rogelj B, Gallo JM, Shaw CE. Allele-specific knockdown of ALS-associated mutant TDP-43 in neural stem cells derived from induced pluripotent stem cells. Plos One. 9: e91269. PMID 24651281 DOI: 10.1371/journal.pone.0091269 |
0.336 |
|
2014 |
Alami NH, Smith RB, Carrasco MA, Williams LA, Winborn CS, Han SS, Kiskinis E, Winborn B, Freibaum BD, Kanagaraj A, Clare AJ, Badders NM, Bilican B, Chaum E, Chandran S, ... ... Maniatis T, et al. Axonal transport of TDP-43 mRNA granules is impaired by ALS-causing mutations. Neuron. 81: 536-43. PMID 24507191 DOI: 10.1016/J.Neuron.2013.12.018 |
0.352 |
|
2013 |
Chen WV, Maniatis T. Clustered protocadherins. Development (Cambridge, England). 140: 3297-302. PMID 23900538 DOI: 10.1242/dev.090621 |
0.495 |
|
2013 |
Bilican B, Serio A, Shaw CE, Maniatis T, Chandran S. Unpicking neurodegeneration in a dish with human pluripotent stem cells: one cell type at a time. Cell Cycle (Georgetown, Tex.). 12: 2339-40. PMID 23856579 DOI: 10.4161/cc.25705 |
0.356 |
|
2013 |
Chiu IM, Morimoto ET, Goodarzi H, Liao JT, O'Keeffe S, Phatnani HP, Muratet M, Carroll MC, Levy S, Tavazoie S, Myers RM, Maniatis T. A neurodegeneration-specific gene-expression signature of acutely isolated microglia from an amyotrophic lateral sclerosis mouse model. Cell Reports. 4: 385-401. PMID 23850290 DOI: 10.1016/J.Celrep.2013.06.018 |
0.79 |
|
2013 |
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, ... ... Maniatis T, et al. Comment on "Drug screening for ALS using patient-specific induced pluripotent stem cells". Science Translational Medicine. 5: 188le2. PMID 23740897 DOI: 10.1126/Scitranslmed.3005065 |
0.646 |
|
2013 |
Larabi A, Devos JM, Ng SL, Nanao MH, Round A, Maniatis T, Panne D. Crystal structure and mechanism of activation of TANK-binding kinase 1. Cell Reports. 3: 734-46. PMID 23453971 DOI: 10.1016/J.Celrep.2013.01.034 |
0.583 |
|
2013 |
Serio A, Bilican B, Barmada SJ, Ando DM, Zhao C, Siller R, Burr K, Haghi G, Story D, Nishimura AL, Carrasco MA, Phatnani HP, Shum C, Wilmut I, Maniatis T, et al. Astrocyte pathology and the absence of non-cell autonomy in an induced pluripotent stem cell model of TDP-43 proteinopathy. Proceedings of the National Academy of Sciences of the United States of America. 110: 4697-702. PMID 23401527 DOI: 10.1073/Pnas.1300398110 |
0.673 |
|
2013 |
Phatnani HP, Guarnieri P, Friedman BA, Carrasco MA, Muratet M, O'Keeffe S, Nwakeze C, Pauli-Behn F, Newberry KM, Meadows SK, Tapia JC, Myers RM, Maniatis T. Intricate interplay between astrocytes and motor neurons in ALS. Proceedings of the National Academy of Sciences of the United States of America. 110: E756-65. PMID 23388633 DOI: 10.1073/Pnas.1222361110 |
0.728 |
|
2012 |
Guo Y, Monahan K, Wu H, Gertz J, Varley KE, Li W, Myers RM, Maniatis T, Wu Q. CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice. Proceedings of the National Academy of Sciences of the United States of America. 109: 21081-6. PMID 23204437 DOI: 10.1073/Pnas.1219280110 |
0.799 |
|
2012 |
Yamazaki T, Chen S, Yu Y, Yan B, Haertlein TC, Carrasco MA, Tapia JC, Zhai B, Das R, Lalancette-Hebert M, Sharma A, Chandran S, Sullivan G, Nishimura AL, Shaw CE, ... ... Maniatis T, et al. FUS-SMN protein interactions link the motor neuron diseases ALS and SMA. Cell Reports. 2: 799-806. PMID 23022481 DOI: 10.1016/J.Celrep.2012.08.025 |
0.513 |
|
2012 |
Li Y, Xiao H, Chiou TT, Jin H, Bonhomme B, Miralles CP, Pinal N, Ali R, Chen WV, Maniatis T, De Blas AL. Molecular and functional interaction between protocadherin-γC5 and GABAA receptors. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 11780-97. PMID 22915120 DOI: 10.1523/Jneurosci.0969-12.2012 |
0.512 |
|
2012 |
Chen WV, Alvarez FJ, Lefebvre JL, Friedman B, Nwakeze C, Geiman E, Smith C, Thu CA, Tapia JC, Tasic B, Sanes JR, Maniatis T. Functional significance of isoform diversification in the protocadherin gamma gene cluster. Neuron. 75: 402-9. PMID 22884324 DOI: 10.1016/J.Neuron.2012.06.039 |
0.723 |
|
2012 |
Lefebvre JL, Kostadinov D, Chen WV, Maniatis T, Sanes JR. Protocadherins mediate dendritic self-avoidance in the mammalian nervous system. Nature. 488: 517-21. PMID 22842903 DOI: 10.1038/Nature11305 |
0.496 |
|
2012 |
Monahan K, Rudnick ND, Kehayova PD, Pauli F, Newberry KM, Myers RM, Maniatis T. Role of CCCTC binding factor (CTCF) and cohesin in the generation of single-cell diversity of protocadherin-α gene expression. Proceedings of the National Academy of Sciences of the United States of America. 109: 9125-30. PMID 22550178 DOI: 10.1073/Pnas.1205074109 |
0.769 |
|
2012 |
Bilican B, Serio A, Barmada SJ, Nishimura AL, Sullivan GJ, Carrasco M, Phatnani HP, Puddifoot CA, Story D, Fletcher J, Park IH, Friedman BA, Daley GQ, Wyllie DJ, Hardingham GE, ... ... Maniatis T, et al. Mutant induced pluripotent stem cell lines recapitulate aspects of TDP-43 proteinopathies and reveal cell-specific vulnerability. Proceedings of the National Academy of Sciences of the United States of America. 109: 5803-8. PMID 22451909 DOI: 10.1073/Pnas.1202922109 |
0.687 |
|
2012 |
Zhao M, Zhang J, Phatnani H, Scheu S, Maniatis T. Stochastic expression of the interferon-β gene Plos Biology. 10. PMID 22291574 DOI: 10.1371/Journal.Pbio.1001249 |
0.662 |
|
2011 |
Ng SL, Friedman BA, Schmid S, Gertz J, Myers RM, Tenoever BR, Maniatis T. IκB kinase epsilon (IKK(epsilon)) regulates the balance between type I and type II interferon responses. Proceedings of the National Academy of Sciences of the United States of America. 108: 21170-5. PMID 22171011 DOI: 10.1073/Pnas.1119137109 |
0.68 |
|
2011 |
Kehayova P, Monahan K, Chen W, Maniatis T. Regulatory elements required for the activation and repression of the protocadherin-á gene cluster Proceedings of the National Academy of Sciences of the United States of America. 108: 17195-17200. PMID 21949399 DOI: 10.1073/Pnas.1114357108 |
0.782 |
|
2011 |
Friedman BA, Maniatis T. ExpressionPlot: A web-based framework for analysis of RNA-Seq and microarray gene expression data Genome Biology. 12. PMID 21797991 DOI: 10.7490/F1000Research.276.1 |
0.315 |
|
2011 |
Ye J, Maniatis T. Negative regulation of interferon-β gene expression during acute and persistent virus infections. Plos One. 6: e20681. PMID 21677781 DOI: 10.1371/journal.pone.0020681 |
0.349 |
|
2010 |
Buchanan SM, Schalm SS, Maniatis T. Proteolytic processing of protocadherin proteins requires endocytosis Proceedings of the National Academy of Sciences of the United States of America. 107: 17774-17779. PMID 20876099 DOI: 10.1073/Pnas.1013105107 |
0.706 |
|
2010 |
Schalm SS, Ballif BA, Buchanan SM, Phillips GR, Maniatis T. Phosphorylation of protocadherin proteins by the receptor tyrosine kinase Ret Proceedings of the National Academy of Sciences of the United States of America. 107: 13894-13899. PMID 20616001 DOI: 10.1073/Pnas.1007182107 |
0.703 |
|
2009 |
Chiu IM, Phatnani H, Kuligowski M, Tapia JC, Carrasco MA, Zhang M, Maniatis T, Carroll MC. Activation of innate and humoral immunity in the peripheral nervous system of ALS transgenic mice. Proceedings of the National Academy of Sciences of the United States of America. 106: 20960-5. PMID 19933335 DOI: 10.1073/Pnas.0911405106 |
0.742 |
|
2008 |
Falvo JV, Lin CH, Tsytsykova AV, Hwang PK, Thanos D, Goldfeld AE, Maniatis T. A dimer-specific function of the transcription factor NFATp Proceedings of the National Academy of Sciences of the United States of America. 105: 19637-19642. PMID 19060202 DOI: 10.1073/Pnas.0810648105 |
0.599 |
|
2008 |
Makeyev EV, Maniatis T. Multilevel regulation of gene expression by microRNAs Science. 319: 1789-1790. PMID 18369137 DOI: 10.1126/science.1152326 |
0.335 |
|
2007 |
Makeyev EV, Zhang J, Carrasco MA, Maniatis T. The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Molecular Cell. 27: 435-48. PMID 17679093 DOI: 10.1016/j.molcel.2007.07.015 |
0.306 |
|
2007 |
Panne D, Maniatis T, Harrison SC. An atomic model of the interferon-beta enhanceosome. Cell. 129: 1111-23. PMID 17574024 DOI: 10.1016/J.Cell.2007.05.019 |
0.39 |
|
2007 |
Panne D, McWhirter SM, Maniatis T, Harrison SC. Interferon regulatory factor 3 is regulated by a dual phosphorylation-dependent switch. The Journal of Biological Chemistry. 282: 22816-22. PMID 17526488 DOI: 10.1074/Jbc.M703019200 |
0.307 |
|
2007 |
Di Giorgio FP, Carrasco MA, Siao MC, Maniatis T, Eggan K. Non-cell autonomous effect of glia on motor neurons in an embryonic stem cell-based ALS model. Nature Neuroscience. 10: 608-14. PMID 17435754 DOI: 10.1038/Nn1885 |
0.767 |
|
2007 |
Tenoever BR, Ng SL, Chua MA, McWhirter SM, García-Sastre A, Maniatis T. Multiple functions of the IKK-related kinase IKKepsilon in interferon-mediated antiviral immunity. Science (New York, N.Y.). 315: 1274-8. PMID 17332413 DOI: 10.1126/Science.1136567 |
0.637 |
|
2006 |
Ribich S, Tasic B, Maniatis T. Identification of long-range regulatory elements in the protocadherin-alpha gene cluster. Proceedings of the National Academy of Sciences of the United States of America. 103: 19719-24. PMID 17172445 DOI: 10.1073/Pnas.0609445104 |
0.792 |
|
2006 |
Maciag K, Altschuler SJ, Slack MD, Krogan NJ, Emili A, Greenblatt JF, Maniatis T, Wu LF. Systems-level analyses identify extensive coupling among gene expression machines. Molecular Systems Biology. 2: 2006.0003. PMID 16738550 DOI: 10.1038/Msb4100045 |
0.346 |
|
2005 |
Zhou R, Silverman N, Hong M, Liao DS, Chung Y, Chen ZJ, Maniatis T. The role of ubiquitination in Drosophila innate immunity Journal of Biological Chemistry. 280: 34048-34055. PMID 16081424 DOI: 10.1074/Jbc.M506655200 |
0.428 |
|
2005 |
Takahara T, Tasic B, Maniatis T, Akanuma H, Yanagisawa S. Delay in synthesis of the 3' splice site promotes trans-splicing of the preceding 5' splice site. Molecular Cell. 18: 245-51. PMID 15837427 DOI: 10.1016/J.Molcel.2005.03.018 |
0.64 |
|
2005 |
Ibrahim EC, Schaal TD, Hertel KJ, Reed R, Maniatis T. Serine/arginine-rich protein-dependent suppression of exon skipping by exonic splicing enhancers. Proceedings of the National Academy of Sciences of the United States of America. 102: 5002-7. PMID 15753297 DOI: 10.1073/Pnas.0500543102 |
0.55 |
|
2004 |
Panne D, Maniatis T, Harrison SC. Crystal structure of ATF-2/c-Jun and IRF-3 bound to the interferon-β enhancer Embo Journal. 23: 4384-4393. PMID 15510218 DOI: 10.1038/Sj.Emboj.7600453 |
0.414 |
|
2004 |
McWhirter SM, Fitzgerald KA, Rosains J, Rowe DC, Golenbock DT, Maniatis T. IFN-regulatory factor 3-dependent gene expression is defective in Tbk1-deficient mouse embryonic fibroblasts Proceedings of the National Academy of Sciences of the United States of America. 101: 233-238. PMID 14679297 DOI: 10.1073/Pnas.2237236100 |
0.433 |
|
2003 |
Silverman N, Zhou R, Erlich RL, Hunter M, Bernstein E, Schneider D, Maniatis T. Immune activation of NF-kappaB and JNK requires Drosophila TAK1. The Journal of Biological Chemistry. 278: 48928-48934. PMID 14519762 DOI: 10.1074/Jbc.M304802200 |
0.316 |
|
2003 |
Stoven S, Silverman N, Junell A, Hedengren-Olcott M, Erturk D, Engstrom Y, Maniatis T, Hultmark D. Caspase-mediated processing of the Drosophila NF-kappaB factor Relish. Proceedings of the National Academy of Sciences of the United States of America. 100: 5991-6. PMID 12732719 DOI: 10.1073/pnas.1035902100 |
0.373 |
|
2003 |
Fitzgerald KA, McWhirter SM, Faia KL, Rowe DC, Latz E, Golenbock DT, Coyle AJ, Liao SM, Maniatis T. IKKE and TBKI are essential components of the IRF3 signalling pathway Nature Immunology. 4: 491-496. PMID 12692549 DOI: 10.1038/Ni921 |
0.308 |
|
2002 |
Tasic B, Nabholz CE, Baldwin KK, Kim Y, Rueckert EH, Ribich SA, Cramer P, Wu Q, Axel R, Maniatis T. Promoter choice determines splice site selection in protocadherin alpha and gamma pre-mRNA splicing. Molecular Cell. 10: 21-33. PMID 12150904 DOI: 10.1016/S1097-2765(02)00578-6 |
0.794 |
|
2002 |
Maniatis T, Tasic B. Alternative pre-mRNA splicing and proteome expansion in metazoans. Nature. 418: 236-43. PMID 12110900 DOI: 10.1038/418236A |
0.622 |
|
2002 |
Maniatis T, Reed R. An extensive network of coupling among gene expression machines. Nature. 416: 499-506. PMID 11932736 DOI: 10.1038/416499A |
0.528 |
|
2001 |
Lin CH, Hare BJ, Wagner G, Harrison SC, Maniatis T, Fraenkel E. A small domain of CBP/p300 binds diverse proteins: solution structure and functional studies. Molecular Cell. 8: 581-90. PMID 11583620 DOI: 10.1016/S1097-2765(01)00333-1 |
0.567 |
|
2001 |
Graveley BR, Hertel KJ, Maniatis T. The role of U2AF35 and U2AF65 in enhancer-dependent splicing. Rna (New York, N.Y.). 7: 806-18. PMID 11421359 DOI: 10.1017/S1355838201010317 |
0.634 |
|
2001 |
Wu Q, Zhang T, Cheng JF, Kim Y, Grimwood J, Schmutz J, Dickson M, Noonan JP, Zhang MQ, Myers RM, Maniatis T. Comparative DNA sequence analysis of mouse and human protocadherin gene clusters. Genome Research. 11: 389-404. PMID 11230163 DOI: 10.1101/Gr.167301 |
0.792 |
|
2000 |
Agalioti T, Lomvardas S, Parekh B, Yie J, Maniatis T, Thanos D. Ordered recruitment of chromatin modifying and general transcription factors to the IFN-beta promoter. Cell. 103: 667-78. PMID 11106736 DOI: 10.1016/S0092-8674(00)00169-0 |
0.37 |
|
2000 |
Silverman N, Zhou R, Stöven S, Pandey N, Hultmark D, Maniatis T. A Drosophila IkappaB kinase complex required for Relish cleavage and antibacterial immunity. Genes & Development. 14: 2461-71. PMID 11018014 DOI: 10.1101/Gad.817800 |
0.427 |
|
2000 |
Falvo JV, Parekh BS, Lin CH, Fraenkel E, Maniatis T. Assembly of a functional beta interferon enhanceosome is dependent on ATF-2-c-jun heterodimer orientation. Molecular and Cellular Biology. 20: 4814-25. PMID 10848607 DOI: 10.1128/Mcb.20.13.4814-4825.2000 |
0.588 |
|
2000 |
Wu Q, Maniatis T. Large exons encoding multiple ectodomains are a characteristic feature of protocadherin genes. Proceedings of the National Academy of Sciences of the United States of America. 97: 3124-9. PMID 10716726 DOI: 10.1073/Pnas.97.7.3124 |
0.571 |
|
2000 |
Falvo JV, Uglialoro AM, Brinkman BM, Merika M, Parekh BS, Tsai EY, King HC, Morielli AD, Peralta EG, Maniatis T, Thanos D, Goldfeld AE. Stimulus-specific assembly of enhancer complexes on the tumor necrosis factor alpha gene promoter. Molecular and Cellular Biology. 20: 2239-47. PMID 10688670 DOI: 10.1128/Mcb.20.6.2239-2247.2000 |
0.318 |
|
1999 |
Wu Q, Maniatis T. A striking organization of a large family of human neural cadherin-like cell adhesion genes. Cell. 97: 779-90. PMID 10380929 DOI: 10.1016/S0092-8674(00)80789-8 |
0.573 |
|
1999 |
Hertel KJ, Maniatis T. Serine-arginine (SR)-rich splicing factors have an exon-independent function in pre-mRNA splicing. Proceedings of the National Academy of Sciences of the United States of America. 96: 2651-5. PMID 10077565 DOI: 10.1073/Pnas.96.6.2651 |
0.38 |
|
1999 |
Parekh BS, Maniatis T. Virus infection leads to localized hyperacetylation of histones H3 and H4 at the IFN-beta promoter. Molecular Cell. 3: 125-9. PMID 10024886 DOI: 10.1016/S1097-2765(00)80181-1 |
0.361 |
|
1999 |
Schaal TD, Maniatis T. Selection and characterization of pre-mRNA splicing enhancers: identification of novel SR protein-specific enhancer sequences. Molecular and Cellular Biology. 19: 1705-19. PMID 10022858 DOI: 10.1128/Mcb.19.3.1705 |
0.379 |
|
1999 |
Graveley BR, Hertel KJ, Maniatis T. SR proteins are 'locators' of the RNA splicing machinery. Current Biology : Cb. 9: R6-7. PMID 9889128 DOI: 10.1016/S0960-9822(99)80032-3 |
0.544 |
|
1999 |
Ren B, Chee KJ, Kim TH, Maniatis T. PRDI-BF1/Blimp-1 repression is mediated by corepressors of the Groucho family of proteins. Genes & Development. 13: 125-37. PMID 9887105 DOI: 10.1101/Gad.13.1.125 |
0.687 |
|
1999 |
Schaal TD, Maniatis T. Multiple distinct splicing enhancers in the protein-coding sequences of a constitutively spliced pre-mRNA. Molecular and Cellular Biology. 19: 261-73. PMID 9858550 DOI: 10.1128/Mcb.19.1.261 |
0.386 |
|
1998 |
Maniatis T, Falvo JV, Kim TH, Kim TK, Lin CH, Parekh BS, Wathelet MG. Structure and function of the interferon-beta enhanceosome. Cold Spring Harbor Symposia On Quantitative Biology. 63: 609-20. PMID 10384326 DOI: 10.1101/SQB.1998.63.609 |
0.585 |
|
1998 |
Graveley BR, Hertel KJ, Maniatis T. A systematic analysis of the factors that determine the strength of pre-mRNA splicing enhancers. The Embo Journal. 17: 6747-56. PMID 9822617 DOI: 10.1093/Emboj/17.22.6747 |
0.621 |
|
1998 |
Kim TK, Kim TH, Maniatis T. Efficient recruitment of TFIIB and CBP-RNA polymerase II holoenzyme by an interferon-beta enhanceosome in vitro. Proceedings of the National Academy of Sciences of the United States of America. 95: 12191-6. PMID 9770462 DOI: 10.1073/pnas.95.21.12191 |
0.538 |
|
1998 |
Graveley BR, Maniatis T. Arginine/serine-rich domains of SR proteins can function as activators of pre-mRNA splicing. Molecular Cell. 1: 765-71. PMID 9660960 DOI: 10.1016/S1097-2765(00)80076-3 |
0.602 |
|
1998 |
Wathelet MG, Lin CH, Parekh BS, Ronco LV, Howley PM, Maniatis T. Virus infection induces the assembly of coordinately activated transcription factors on the IFN-beta enhancer in vivo. Molecular Cell. 1: 507-18. PMID 9660935 DOI: 10.1016/S1097-2765(00)80051-9 |
0.601 |
|
1998 |
Hertel KJ, Maniatis T. The function of multisite splicing enhancers. Molecular Cell. 1: 449-55. PMID 9660929 DOI: 10.1016/S1097-2765(00)80045-3 |
0.36 |
|
1998 |
Ren B, Maniatis T. Regulation of Drosophila Adh promoter switching by an initiator-targeted repression mechanism. The Embo Journal. 17: 1076-86. PMID 9463385 DOI: 10.1093/Emboj/17.4.1076 |
0.602 |
|
1998 |
Sears C, Olesen J, Rubin D, Finley D, Maniatis T. NF-kappa B p105 processing via the ubiquitin-proteasome pathway. The Journal of Biological Chemistry. 273: 1409-19. PMID 9430676 DOI: 10.1074/Jbc.273.3.1409 |
0.735 |
|
1997 |
Kim TK, Maniatis T. The mechanism of transcriptional synergy of an in vitro assembled interferon-beta enhanceosome. Molecular Cell. 1: 119-29. PMID 9659909 DOI: 10.1016/S1097-2765(00)80013-1 |
0.422 |
|
1997 |
Hertel KJ, Lynch KW, Maniatis T. Common themes in the function of transcription and splicing enhancers. Current Opinion in Cell Biology. 9: 350-7. PMID 9159075 DOI: 10.1016/S0955-0674(97)80007-5 |
0.604 |
|
1997 |
Yang JH, Sklar P, Axel R, Maniatis T. Purification and characterization of a human RNA adenosine deaminase for glutamate receptor B pre-mRNA editing. Proceedings of the National Academy of Sciences of the United States of America. 94: 4354-9. PMID 9113993 DOI: 10.1073/pnas.94.9.4354 |
0.562 |
|
1997 |
Powell DM, Amaral MC, Wu JY, Maniatis T, Greene WC. HIV Rev-dependent binding of SF2/ASF to the Rev response element: possible role in Rev-mediated inhibition of HIV RNA splicing. Proceedings of the National Academy of Sciences of the United States of America. 94: 973-8. PMID 9023367 DOI: 10.1073/pnas.94.3.973 |
0.339 |
|
1996 |
Thanos D, Maniatis T. In vitro assembly of enhancer complexes. Methods in Enzymology. 274: 162-73. PMID 8902803 DOI: 10.1016/S0076-6879(96)74015-6 |
0.372 |
|
1996 |
Hertel KJ, Lynch KW, Hsiao EC, Liu EH, Maniatis T. Structural and functional conservation of the Drosophila doublesex splicing enhancer repeat elements. Rna (New York, N.Y.). 2: 969-81. PMID 8849774 |
0.519 |
|
1996 |
Kim TK, Maniatis T. Regulation of interferon-gamma-activated STAT1 by the ubiquitin-proteasome pathway. Science (New York, N.Y.). 273: 1717-9. PMID 8781235 DOI: 10.1126/Science.273.5282.1717 |
0.332 |
|
1996 |
Lynch KW, Maniatis T. Assembly of specific SR protein complexes on distinct regulatory elements of the Drosophila doublesex splicing enhancer. Genes & Development. 10: 2089-101. PMID 8769651 DOI: 10.1101/Gad.10.16.2089 |
0.582 |
|
1995 |
Falvo JV, Thanos D, Maniatis T. Reversal of intrinsic DNA bends in the IFN beta gene enhancer by transcription factors and the architectural protein HMG I(Y). Cell. 83: 1101-11. PMID 8548798 DOI: 10.1016/0092-8674(95)90137-X |
0.393 |
|
1995 |
Thanos D, Maniatis T. Virus induction of human IFN beta gene expression requires the assembly of an enhanceosome. Cell. 83: 1091-100. PMID 8548797 DOI: 10.1016/0092-8674(95)90136-1 |
0.42 |
|
1995 |
Hedley ML, Amrein H, Maniatis T. An amino acid sequence motif sufficient for subnuclear localization of an arginine/serine-rich splicing factor. Proceedings of the National Academy of Sciences of the United States of America. 92: 11524-8. PMID 8524796 DOI: 10.1073/pnas.92.25.11524 |
0.666 |
|
1995 |
Yang JH, Sklar P, Axel R, Maniatis T. Editing of glutamate receptor subunit B pre-mRNA in vitro by site-specific deamination of adenosine. Nature. 374: 77-81. PMID 7870177 DOI: 10.1038/374077a0 |
0.557 |
|
1995 |
Lynch KW, Maniatis T. Synergistic interactions between two distinct elements of a regulated splicing enhancer. Genes & Development. 9: 284-93. PMID 7867927 DOI: 10.1101/Gad.9.3.284 |
0.595 |
|
1995 |
Thanos D, Maniatis T. Identification of the rel family members required for virus induction of the human beta interferon gene Molecular and Cellular Biology. 15: 152-164. PMID 7799921 DOI: 10.1128/Mcb.15.1.152 |
0.384 |
|
1995 |
Lazar G, Schaal T, Maniatis T, Goodman HM. Identification of a plant serine-arginine-rich protein similar to the mammalian splicing factor SF2/ASF. Proceedings of the National Academy of Sciences of the United States of America. 92: 7672-6. PMID 7644475 DOI: 10.1073/Pnas.92.17.7672 |
0.316 |
|
1995 |
Bruzik JP, Maniatis T. Enhancer-dependent interaction between 5' and 3' splice sites in trans. Proceedings of the National Academy of Sciences of the United States of America. 92: 7056-9. PMID 7624368 DOI: 10.1073/Pnas.92.15.7056 |
0.358 |
|
1995 |
Collins T, Read MA, Neish AS, Whitley MZ, Thanos D, Maniatis T. Transcriptional regulation of endothelial cell adhesion molecules: NF-kappa B and cytokine-inducible enhancers. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 9: 899-909. PMID 7542214 DOI: 10.1096/Fasebj.9.10.7542214 |
0.408 |
|
1995 |
Axel R, Maniatis T. Harold Weintraub (1945–1995) Cell. 81: 317-318. DOI: 10.1016/0092-8674(95)90382-8 |
0.48 |
|
1994 |
Tjian R, Maniatis T. Transcriptional activation: A complex puzzle with few easy pieces Cell. 77: 5-8. PMID 8156597 DOI: 10.1016/0092-8674(94)90227-5 |
0.509 |
|
1994 |
Amrein H, Hedley ML, Maniatis T. The role of specific protein-RNA and protein-protein interactions in positive and negative control of pre-mRNA splicing by Transformer 2. Cell. 76: 735-46. PMID 8124712 DOI: 10.1016/0092-8674(94)90512-6 |
0.677 |
|
1994 |
Lehming N, Thanos D, Brickman JM, Ma J, Maniatis T, Ptashne M. An HMG-like protein that can switch a transcriptional activator to a repressor. Nature. 371: 175-9. PMID 8072548 DOI: 10.1038/371175A0 |
0.64 |
|
1994 |
Du W, Maniatis T. The high mobility group protein HMG I(Y) can stimulate or inhibit DNA binding of distinct transcription factor ATF-2 isoforms Proceedings of the National Academy of Sciences of the United States of America. 91: 11318-11322. PMID 7972056 DOI: 10.1073/Pnas.91.24.11318 |
0.376 |
|
1993 |
Du W, Thanos D, Maniatis T. Mechanisms of transcriptional synergism between distinct virus-inducible enhancer elements Cell. 74: 887-898. PMID 8374955 DOI: 10.1016/0092-8674(93)90468-6 |
0.374 |
|
1993 |
Tian M, Maniatis T. A splicing enhancer complex controls alternative splicing of doublesex pre-mRNA Cell. 74: 105-114. PMID 8334698 DOI: 10.1016/0092-8674(93)90298-5 |
0.366 |
|
1993 |
Wu JY, Maniatis T. Specific interactions between proteins implicated in splice site selection and regulated alternative splicing. Cell. 75: 1061-70. PMID 8261509 DOI: 10.1016/0092-8674(93)90316-I |
0.454 |
|
1993 |
Abel T, Michelson AM, Maniatis T. A Drosophila GATA family member that binds to Adh regulatory sequences is expressed in the developing fat body. Development (Cambridge, England). 119: 623-33. PMID 8187633 |
0.641 |
|
1993 |
Winick J, Abel T, Leonard MW, Michelson AM, Chardon-Loriaux I, Holmgren RA, Maniatis T, Engel JD. A GATA family transcription factor is expressed along the embryonic dorsoventral axis in Drosophila melanogaster. Development (Cambridge, England). 119: 1055-65. PMID 7916677 |
0.674 |
|
1992 |
Maniatis T, Weintraub H. Gene expression and differentiation Current Opinion in Genetics and Development. 2: 197-198. PMID 1638112 DOI: 10.1016/S0959-437X(05)80273-4 |
0.336 |
|
1992 |
Palombella VJ, Maniatis T. Inducible processing of interferon regulatory factor-2 Molecular and Cellular Biology. 12: 3325-3336. PMID 1630448 DOI: 10.1128/Mcb.12.8.3325 |
0.41 |
|
1992 |
Keller AD, Maniatis T. Only two of the five zinc fingers of the eukaryotic transcriptional repressor PRDI-BF1 are required for sequence-specific DNA binding Molecular and Cellular Biology. 12: 1940-1949. PMID 1569931 DOI: 10.1128/Mcb.12.5.1940 |
0.375 |
|
1992 |
Tian M, Maniatis T. Positive control of pre-mRNA splicing in vitro Science. 256: 237-240. PMID 1566072 DOI: 10.1126/Science.1566072 |
0.408 |
|
1992 |
Falb D, Maniatis T. A conserved regulatory unit implicated in tissue-specific gene expression in Drosophila and man Genes and Development. 6: 454-465. PMID 1547943 DOI: 10.1101/Gad.6.3.454 |
0.381 |
|
1992 |
Du W, Maniatis T. An ATF/CREB binding site protein is required for virus induction of the human interferon β gene Proceedings of the National Academy of Sciences of the United States of America. 89: 2150-2154. PMID 1532252 DOI: 10.1073/Pnas.89.6.2150 |
0.427 |
|
1992 |
Abel T, Bhatt R, Maniatis T. A Drosophila CREB/ATF transcriptional activator binds to both fat body- and liver-specific regulatory elements. Genes & Development. 6: 466-80. PMID 1532159 DOI: 10.1101/Gad.6.3.466 |
0.579 |
|
1992 |
Fu XD, Maniatis T. The 35-kDa mammalian splicing factor SC35 mediates specific interactions between U1 and U2 small nuclear ribonucleoprotein particles at the 3' splice site Proceedings of the National Academy of Sciences of the United States of America. 89: 1725-1729. PMID 1531875 DOI: 10.1073/Pnas.89.5.1725 |
0.508 |
|
1992 |
Falb D, Maniatis T. Drosophila transcriptional repressor protein that binds specifically to negative control elements in fat body enhancers Molecular and Cellular Biology. 12: 4093-4103. PMID 1508206 DOI: 10.1128/Mcb.12.9.4093 |
0.367 |
|
1992 |
Bruzik JP, Maniatis T. Spliced leader RNAs from lower eukaryotes are trans-spliced in mammalian cells Nature. 360: 692-695. PMID 1465136 DOI: 10.1038/360692a0 |
0.363 |
|
1992 |
Fu XD, Mayeda A, Maniatis T, Krainer AR. General splicing factors SF2 and SC35 have equivalent activities in vitro, and both affect alternative 5' and 3' splice site selection. Proceedings of the National Academy of Sciences of the United States of America. 89: 11224-8. PMID 1454802 DOI: 10.1073/Pnas.89.23.11224 |
0.738 |
|
1992 |
Wigler M, Sweet R, Sim GK, Wold B, Pellicer A, Lacy E, Maniatis T, Silverstein S, Axel R. Transformation of mammalian cells with genes from prokaryotes and eukaryotes. 1979. Biotechnology (Reading, Mass.). 24: 444-52. PMID 1422052 |
0.529 |
|
1992 |
Fu XD, Maniatis T. Isolation of a complementary DNA that encodes the mammalian splicing factor SC35 Science. 256: 535-538. PMID 1373910 DOI: 10.1126/Science.1373910 |
0.572 |
|
1992 |
Thanos D, Maniatis T. The High Mobility Group protein HMG I(Y) is required for NF-κB-dependent virus induction of the human IFN-β gene Cell. 71: 777-789. PMID 1330326 DOI: 10.1016/0092-8674(92)90554-P |
0.389 |
|
1992 |
Maniatis T, Whittemore L, Du W, Fan C, Keller AD, Palombella VJ, Thanos DN. 44 Positive and Negative Control of Human Interferon-β Gene Expression Cold Spring Harbor Monograph Archive. 1193-1220. DOI: 10.1101/087969425.22B.1193 |
0.38 |
|
1991 |
Goldfeld AE, Doyle C, Maniatis T. Human tumor necrosis factor alpha gene regulation by virus and lipopolysaccharide. Proceedings of the National Academy of Sciences of the United States of America. 87: 9769-73. PMID 2263628 DOI: 10.1073/Pnas.87.24.9769 |
0.352 |
|
1991 |
Corbin V, Michelson AM, Abmayr SM, Neel V, Alcamo E, Maniatis T, Young MW. A role for the Drosophila neurogenic genes in mesoderm differentiation. Cell. 67: 311-23. PMID 1913825 DOI: 10.1016/0092-8674(91)90183-Y |
0.796 |
|
1991 |
Keller AD, Maniatis T. Selection of sequences recognized by a DNA binding protein using a preparative southwestern blot. Nucleic Acids Research. 19: 4675-80. PMID 1891359 DOI: 10.1093/NAR/19.17.4675 |
0.351 |
|
1991 |
Keller AD, Maniatis T. Identification and characterization of a novel repressor of beta-interferon gene expression. Genes & Development. 5: 868-79. PMID 1851123 DOI: 10.1101/GAD.5.5.868 |
0.317 |
|
1991 |
Fu XD, Katz RA, Skalka AM, Maniatis T. The role of branchpoint and 3'-exon sequences in the control of balanced splicing of avian retrovirus RNA. Genes & Development. 5: 211-20. PMID 1847346 DOI: 10.1101/Gad.5.2.211 |
0.522 |
|
1991 |
Spector DL, Fu XD, Maniatis T. Associations between distinct pre-mRNA splicing components and the cell nucleus Embo Journal. 10: 3467-3481. PMID 1833187 DOI: 10.1002/J.1460-2075.1991.Tb04911.X |
0.433 |
|
1991 |
Baron MH, Maniatis T. Regulated expression of human alpha- and beta-globin genes in transient heterokaryons. Molecular and Cellular Biology. 11: 1239-47. PMID 1705003 DOI: 10.1128/MCB.11.3.1239 |
0.425 |
|
1991 |
Hedley ML, Maniatis T. Sex-specific splicing and polyadenylation of dsx pre-mRNA requires a sequence that binds specifically to tra-2 protein in vitro. Cell. 65: 579-86. PMID 1674449 DOI: 10.1016/0092-8674(91)90090-L |
0.375 |
|
1990 |
Michelson AM, Abmayr SM, Bate M, Arias AM, Maniatis T. Expression of a MyoD family member prefigures muscle pattern in Drosophila embryos. Genes & Development. 4: 2086-97. PMID 2176634 DOI: 10.1101/Gad.4.12A.2086 |
0.574 |
|
1990 |
Whittemore LA, Maniatis T. Postinduction repression of the beta-interferon gene is mediated through two positive regulatory domains. Proceedings of the National Academy of Sciences of the United States of America. 87: 7799-803. PMID 2172963 DOI: 10.1073/PNAS.87.20.7799 |
0.382 |
|
1990 |
Whittemore LA, Maniatis T. Postinduction turnoff of beta-interferon gene expression. Molecular and Cellular Biology. 10: 1329-37. PMID 2157136 DOI: 10.1128/MCB.10.4.1329 |
0.373 |
|
1990 |
Fu XD, Maniatis T. Factor required for mammalian spliceosome assembly is localized to discrete regions in the nucleus. Nature. 343: 437-41. PMID 2137203 DOI: 10.1038/343437A0 |
0.467 |
|
1990 |
Amrein H, Maniatis T, Nöthiger R. Alternatively spliced transcripts of the sex-determining gene tra-2 of Drosophila encode functional proteins of different size. The Embo Journal. 9: 3619-29. PMID 2120049 DOI: 10.1002/J.1460-2075.1990.Tb07573.X |
0.786 |
|
1989 |
Goto T, Macdonald P, Maniatis T. Early and late periodic patterns of even skipped expression are controlled by distinct regulatory elements that respond to different spatial cues. Cell. 57: 413-22. PMID 2720776 DOI: 10.1016/0092-8674(89)90916-1 |
0.341 |
|
1989 |
Abel T, Maniatis T. Gene regulation. Action of leucine zippers. Nature. 341: 24-5. PMID 2671752 DOI: 10.1038/341024a0 |
0.518 |
|
1989 |
Goldfeld AE, Maniatis T. Coordinate viral induction of tumor necrosis factor alpha and interferon beta in human B cells and monocytes. Proceedings of the National Academy of Sciences of the United States of America. 86: 1490-4. PMID 2537976 DOI: 10.1073/Pnas.86.5.1490 |
0.376 |
|
1989 |
Munro S, Maniatis T. Expression cloning of the murine interferon gamma receptor cDNA. Proceedings of the National Academy of Sciences of the United States of America. 86: 9248-52. PMID 2531896 DOI: 10.1073/pnas.86.23.9248 |
0.324 |
|
1989 |
Lenardo MJ, Fan CM, Maniatis T, Baltimore D. The involvement of NF-kappa B in beta-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell. 57: 287-94. PMID 2495183 DOI: 10.1016/0092-8674(89)90966-5 |
0.532 |
|
1989 |
Corbin V, Maniatis T. Role of transcriptional interference in the Drosophila melanogaster Adh promoter switch. Nature. 337: 279-82. PMID 2492088 DOI: 10.1038/337279A0 |
0.319 |
|
1989 |
Fan CM, Maniatis T. Two different virus-inducible elements are required for human beta-interferon gene regulation. The Embo Journal. 8: 101-110. DOI: 10.1002/j.1460-2075.1989.tb03353.x |
0.367 |
|
1988 |
Goodbourn S, Maniatis T. Overlapping positive and negative regulatory domains of the human beta-interferon gene. Proceedings of the National Academy of Sciences of the United States of America. 85: 1447-51. PMID 3422743 DOI: 10.1073/PNAS.85.5.1447 |
0.436 |
|
1988 |
Keller AD, Maniatis T. Identification of an inducible factor that binds to a positive regulatory element of the human beta-interferon gene. Proceedings of the National Academy of Sciences of the United States of America. 85: 3309-13. PMID 3368441 DOI: 10.1073/PNAS.85.10.3309 |
0.447 |
|
1988 |
Fischer JA, Maniatis T. Drosophila Adh: A promoter element expands the tissue specificity of an enhancer Cell. 53: 451-461. PMID 3365768 DOI: 10.1016/0092-8674(88)90165-1 |
0.316 |
|
1988 |
Zinn K, Keller A, Whittemore LA, Maniatis T. 2-Aminopurine selectively inhibits the induction of beta-interferon, c-fos, and c-myc gene expression. Science (New York, N.Y.). 240: 210-3. PMID 3281258 DOI: 10.1126/Science.3281258 |
0.575 |
|
1988 |
Fischer JA, Giniger E, Maniatis T, Ptashne M. GAL4 activates transcription in Drosophila. Nature. 332: 853-6. PMID 3128741 DOI: 10.1038/332853A0 |
0.757 |
|
1988 |
Reed R, Maniatis T. The role of the mammalian branchpoint sequence in pre-mRNA splicing. Genes & Development. 2: 1268-76. PMID 3060403 DOI: 10.1101/Gad.2.10.1268 |
0.465 |
|
1988 |
Abmayr SM, Reed R, Maniatis T. Identification of a functional mammalian spliceosome containing unspliced pre-mRNA. Proceedings of the National Academy of Sciences of the United States of America. 85: 7216-20. PMID 2971971 DOI: 10.1073/Pnas.85.19.7216 |
0.482 |
|
1988 |
Reed R, Griffith J, Maniatis T. Purification and visualization of native spliceosomes. Cell. 53: 949-61. PMID 2968159 DOI: 10.1016/S0092-8674(88)90489-8 |
0.449 |
|
1987 |
Myers RM, Maniatis T, Lerman LS. Detection and localization of single base changes by denaturing gradient gel electrophoresis. Methods in Enzymology. 155: 501-27. PMID 3431470 DOI: 10.1016/0076-6879(87)55033-9 |
0.711 |
|
1987 |
Maniatis T, Goodbourn S, Fischer JA. Regulation of inducible and tissue-specific gene expression Science. 236: 1237-1245. PMID 3296191 DOI: 10.1126/Science.3296191 |
0.445 |
|
1987 |
Maniatis T, Reed R. The role of small nuclear ribonucleoprotein particles in pre-mRNA splicing. Nature. 325: 673-8. PMID 2950324 DOI: 10.1038/325673A0 |
0.51 |
|
1987 |
Atweh GF, Wong C, Reed R, Antonarakis SE, Zhu D, Ghosh PK, Maniatis T, Forget BG, Kazazian HH. A new mutation in IVS-1 of the human beta globin gene causing beta thalassemia due to abnormal splicing. Blood. 70: 147-51. PMID 2439149 |
0.511 |
|
1986 |
Myers RM, Larin Z, Maniatis T. Detection of single base substitutions by ribonuclease cleavage at mismatches in RNA:DNA duplexes. Science (New York, N.Y.). 230: 1242-6. PMID 4071043 DOI: 10.1126/Science.4071043 |
0.53 |
|
1986 |
Enoch T, Zinn K, Maniatis T. Activation of the human beta-interferon gene requires an interferon-inducible factor. Molecular and Cellular Biology. 6: 801-10. PMID 3773893 |
0.52 |
|
1986 |
Baron MH, Maniatis T. Rapid reprogramming of globin gene expression in transient heterokaryons. Cell. 46: 591-602. PMID 3731277 DOI: 10.1016/0092-8674(86)90885-8 |
0.416 |
|
1986 |
Zinn K, Maniatis T. Detection of factors that interact with the human beta-interferon regulatory region in vivo by DNAase I footprinting. Cell. 45: 611-8. PMID 3708689 DOI: 10.1016/0092-8674(86)90293-X |
0.585 |
|
1986 |
Goodbourn S, Burstein H, Maniatis T. The human beta-interferon gene enhancer is under negative control. Cell. 45: 601-10. PMID 3708688 DOI: 10.1016/0092-8674(86)90292-8 |
0.398 |
|
1986 |
Myers RM, Tilly K, Maniatis T. Fine structure genetic analysis of a beta-globin promoter. Science (New York, N.Y.). 232: 613-8. PMID 3457470 DOI: 10.1126/Science.3457470 |
0.59 |
|
1986 |
Reed R, Maniatis T. A role for exon sequences and splice-site proximity in splice-site selection. Cell. 46: 681-90. PMID 2427200 DOI: 10.1016/0092-8674(86)90343-0 |
0.519 |
|
1985 |
Myers RM, Fischer SG, Lerman LS, Maniatis T. Nearly all single base substitutions in DNA fragments joined to a GC-clamp can be detected by denaturing gradient gel electrophoresis. Nucleic Acids Research. 13: 3131-45. PMID 4000972 DOI: 10.1093/Nar/13.9.3131 |
0.722 |
|
1985 |
Goodbourn S, Zinn K, Maniatis T. Human beta-interferon gene expression is regulated by an inducible enhancer element. Cell. 41: 509-20. PMID 3986910 DOI: 10.1016/S0092-8674(85)80024-6 |
0.596 |
|
1985 |
Myers RM, Lumelsky N, Lerman LS, Maniatis T. Detection of single base substitutions in total genomic DNA. Nature. 313: 495-8. PMID 3969155 DOI: 10.1038/313495a0 |
0.722 |
|
1985 |
Reed R, Maniatis T. Intron sequences involved in lariat formation during pre-mRNA splicing. Cell. 41: 95-105. PMID 3888410 DOI: 10.1016/0092-8674(85)90064-9 |
0.541 |
|
1985 |
Charnay P, Mellon P, Maniatis T. Linker scanning mutagenesis of the 5'-flanking region of the mouse beta-major-globin gene: sequence requirements for transcription in erythroid and nonerythroid cells. Molecular and Cellular Biology. 5: 1498-511. PMID 3861935 DOI: 10.1128/Mcb.5.6.1498 |
0.662 |
|
1985 |
Posakony JW, Fischer JA, Maniatis T. Identification of DNA sequences required for the regulation of Drosophila alcohol dehydrogenase gene expression. Cold Spring Harbor Symposia On Quantitative Biology. 50: 515-20. PMID 3007005 DOI: 10.1101/Sqb.1985.050.01.063 |
0.65 |
|
1985 |
Fischer JA, Maniatis T. Structure and transcription of the Drosophila mulleri alcohol dehydrogenase genes Nucleic Acids Research. 13: 6899-6917. PMID 2997730 DOI: 10.1093/Nar/13.19.6899 |
0.358 |
|
1985 |
Krainer AR, Maniatis T. Multiple factors including the small nuclear ribonucleoproteins U1 and U2 are necessary for pre-mRNA splicing in vitro. Cell. 42: 725-36. PMID 2996774 DOI: 10.1016/0092-8674(85)90269-7 |
0.661 |
|
1985 |
Myers RM, Lerman LS, Maniatis T. A general method for saturation mutagenesis of cloned DNA fragments. Science (New York, N.Y.). 229: 242-7. PMID 2990046 DOI: 10.1126/Science.2990046 |
0.716 |
|
1985 |
Myers RM, Fischer SG, Maniatis T, Lerman LS. Modification of the melting properties of duplex DNA by attachment of a GC-rich DNA sequence as determined by denaturing gradient gel electrophoresis. Nucleic Acids Research. 13: 3111-29. PMID 2987873 DOI: 10.1093/Nar/13.9.3111 |
0.724 |
|
1985 |
Treisman R, Maniatis T. Simian virus 40 enhancer increases number of RNA polymerase II molecules on linked DNA. Nature. 315: 73-5. PMID 2986013 DOI: 10.1038/315072A0 |
0.41 |
|
1985 |
Zuber P, Losick R, Struhl K, Chen W, Hill DE, Hope IA, Oettinger MA, Savakis C, Ashburner M, Posakony JW, Fischer JA, Maniatis T, Wensink PC, Shepherd B, Garabedian MJ, et al. Control of gene expression Cold Spring Harbor Symposia On Quantitative Biology. 50: 483-563. DOI: 10.1016/B978-0-12-455620-1.50012-6 |
0.321 |
|
1984 |
Krainer AR, Maniatis T, Ruskin B, Green MR. Normal and mutant human beta-globin pre-mRNAs are faithfully and efficiently spliced in vitro. Cell. 36: 993-1005. PMID 6323033 DOI: 10.1016/0092-8674(84)90049-7 |
0.691 |
|
1984 |
DiMaio D, Corbin V, Sibley E, Maniatis T. High-level expression of a cloned HLA heavy chain gene introduced into mouse cells on a bovine papillomavirus vector. Molecular and Cellular Biology. 4: 340-50. PMID 6321959 DOI: 10.1128/MCB.4.2.340 |
0.596 |
|
1984 |
Charnay P, Treisman R, Mellon P, Chao M, Axel R, Maniatis T. Differences in human alpha- and beta-globin gene expression in mouse erythroleukemia cells: the role of intragenic sequences. Cell. 38: 251-63. PMID 6205764 DOI: 10.1016/0092-8674(84)90547-6 |
0.728 |
|
1984 |
Treisman R, Green MR, Maniatis T. cis and trans activation of globin gene transcription in transient assays. Proceedings of the National Academy of Sciences of the United States of America. 80: 7428-32. PMID 6200874 DOI: 10.1073/Pnas.80.24.7428 |
0.431 |
|
1984 |
Charnay P, Treisman R, Mellon P, Chao M, Axel R, Maniatis T. Human alpha- and beta-globin gene transcription in mouse erythroleukaemia cells. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 307: 261-70. PMID 6151696 DOI: 10.1098/Rstb.1984.0126 |
0.727 |
|
1984 |
Melton DA, Krieg PA, Rebagliati MR, Maniatis T, Zinn K, Green MR. Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter. Nucleic Acids Research. 12: 7035-56. PMID 6091052 DOI: 10.1093/Nar/12.18.7035 |
0.525 |
|
1984 |
Ruskin B, Krainer AR, Maniatis T, Green MR. Excision of an intact intron as a novel lariat structure during pre-mRNA splicing in vitro. Cell. 38: 317-31. PMID 6088074 DOI: 10.1016/0092-8674(84)90553-1 |
0.675 |
|
1983 |
Mellon P, Charnay P, Chao M, Axel R, Maniatis T. Regulated expression of cloned globin genes introduced into mouse erythroleukemia cells. Progress in Clinical and Biological Research. 134: 3-12. PMID 6582520 |
0.695 |
|
1983 |
Charnay P, Maniatis T. Transcriptional regulation of globin gene expression in the human erythroid cell line K562. Science (New York, N.Y.). 220: 1281-3. PMID 6574602 DOI: 10.1126/Science.6574602 |
0.609 |
|
1983 |
Chao MV, Mellon P, Charnay P, Maniatis T, Axel R. The regulated expression of beta-globin genes introduced into mouse erythroleukemia cells. Cell. 32: 483-93. PMID 6572107 DOI: 10.1016/0092-8674(83)90468-3 |
0.739 |
|
1983 |
Green MR, Maniatis T, Melton DA. Human beta-globin pre-mRNA synthesized in vitro is accurately spliced in Xenopus oocyte nuclei. Cell. 32: 681-94. PMID 6550524 DOI: 10.1016/0092-8674(83)90054-5 |
0.38 |
|
1983 |
Green MR, Treisman R, Maniatis T. Transcriptional activation of cloned human beta-globin genes by viral immediate-early gene products. Cell. 35: 137-48. PMID 6313220 DOI: 10.1016/0092-8674(83)90216-7 |
0.453 |
|
1983 |
Zinn K, DiMaio D, Maniatis T. Identification of two distinct regulatory regions adjacent to the human beta-interferon gene. Cell. 34: 865-79. PMID 6313211 DOI: 10.1016/0092-8674(83)90544-5 |
0.722 |
|
1983 |
Goldberg DA, Posakony JW, Maniatis T. Correct developmental expression of a cloned alcohol dehydrogenase gene transduced into the Drosophila germ line. Cell. 34: 59-73. PMID 6309412 DOI: 10.1016/0092-8674(83)90136-8 |
0.656 |
|
1983 |
Treisman R, Orkin SH, Maniatis T. Specific transcription and RNA splicing defects in five cloned β-thalassaemia genes Nature. 302: 591-596. PMID 6188062 DOI: 10.1038/302591A0 |
0.408 |
|
1983 |
Chao MV, Mellon P, Charnay P, Maniatis T, Axel R. Introduction and expression of beta-globin genes in murine erythroleukemic cells. Gene Amplification and Analysis. 3: 215-31. PMID 6101028 |
0.682 |
|
1983 |
Little PF, Treisman R, Bierut L, Seed B, Maniatis T. Plasmid vectors for the rapid isolation and transcriptional analysis of human beta-globin gene alleles. Molecular Biology & Medicine. 1: 473-88. PMID 6094959 |
0.589 |
|
1982 |
Treisman R, Proudfoot NJ, Shander M, Maniatis T. A single-base change at a splice site in a beta 0-thalassemic gene causes abnormal RNA splicing. Cell. 29: 903-11. PMID 7151176 DOI: 10.1016/0092-8674(82)90452-4 |
0.605 |
|
1982 |
Zinn K, Mellon P, Ptashne M, Maniatis T. Regulated expression of an extrachromosomal human beta-interferon gene in mouse cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 4897-901. PMID 6956899 DOI: 10.1073/Pnas.79.16.4897 |
0.693 |
|
1982 |
Proudfoot NJ, Gil A, Maniatis T. The structure of the human zeta-globin gene and a closely linked, nearly identical pseudogene. Cell. 31: 553-63. PMID 6297773 DOI: 10.1016/0092-8674(82)90311-7 |
0.606 |
|
1982 |
DiMaio D, Treisman R, Maniatis T. Bovine papillomavirus vector that propagates as a plasmid in both mouse and bacterial cells. Proceedings of the National Academy of Sciences of the United States of America. 79: 4030-4. PMID 6287462 DOI: 10.1073/Pnas.79.13.4030 |
0.627 |
|
1981 |
Shen CK, Maniatis T. Tissue-specific DNA methylation in a cluster of rabbit beta-like globin genes. Proceedings of the National Academy of Sciences of the United States of America. 77: 6634-8. PMID 6935674 DOI: 10.1073/PNAS.77.11.6634 |
0.384 |
|
1981 |
Maniatis T, Fritsch EF, Lauer J, Lawn RM. The molecular genetics of human hemoglobins. Annual Review of Genetics. 14: 145-78. PMID 6452087 DOI: 10.1146/ANNUREV.GE.14.120180.001045 |
0.384 |
|
1981 |
Mellon P, Parker V, Gluzman Y, Maniatis T. Identification of DNA sequences required for transcription of the human α1-globin gene in a new SV40 host-vector system Cell. 27: 279-288. PMID 6277501 DOI: 10.1016/0092-8674(81)90411-6 |
0.41 |
|
1981 |
Fritsch EF, Shen CK, Lawn RM, Maniatis T. The organization of repetitive sequences in mammalian globin gene clusters. Cold Spring Harbor Symposia On Quantitative Biology. 761-5. PMID 6167396 DOI: 10.1101/SQB.1981.045.01.095 |
0.321 |
|
1980 |
Lacy E, Maniatis T. The nucleotide sequence of a rabbit beta-globin pseudogene. Cell. 21: 545-53. PMID 7407926 DOI: 10.1016/0092-8674(80)90492-4 |
0.343 |
|
1980 |
Proudfoot NJ, Maniatis T. The structure of a human alpha-globin pseudogene and its relationship to alpha-globin gene duplication. Cell. 21: 537-44. PMID 7407925 DOI: 10.1016/0092-8674(80)90491-2 |
0.527 |
|
1980 |
Efstratiadis A, Posakony JW, Maniatis T, Lawn RM, O'Connell C, Spritz RA, DeRiel JK, Forget BG, Weissman SM, Slightom JL, Blechl AE, Smithies O, Baralle FE, Shoulders CC, Proudfoot NJ. The structure and evolution of the human beta-globin gene family. Cell. 21: 653-68. PMID 6985477 DOI: 10.1016/0092-8674(80)90429-8 |
0.745 |
|
1980 |
Lauer J, Shen CKJ, Maniatis T. The chromosomal arrangement of human α-like globin genes: Sequence homology and α-globin gene deletions Cell. 20: 119-130. PMID 6446404 DOI: 10.1016/0092-8674(80)90240-8 |
0.363 |
|
1980 |
Lawn RM, Efstratiadis A, O'Connell C, Maniatis T. The nucleotide sequence of the human beta-globin gene. Cell. 21: 647-51. PMID 6254664 DOI: 10.1016/0092-8674(80)90428-6 |
0.381 |
|
1980 |
Shen CK, Maniatis T. The organization of repetitive sequences in a cluster of rabbit beta-like globin genes. Cell. 19: 379-91. PMID 6244107 DOI: 10.1016/0092-8674(80)90512-7 |
0.387 |
|
1980 |
Proudfoot NJ, Shander MH, Manley JL, Gefter ML, Maniatis T. Structure and in vitro transcription of human globin genes. Science (New York, N.Y.). 209: 1329-36. PMID 6158093 DOI: 10.1126/Science.6158093 |
0.619 |
|
1980 |
Fritsch EF, Lawn RM, Maniatis T. Molecular cloning and characterization of the human β-like globin gene cluster Cell. 19: 959-972. PMID 6155216 DOI: 10.1016/0092-8674(80)90087-2 |
0.367 |
|
1979 |
Sim GK, Kafatos FC, Jones CW, Koehler MD, Efstratiadis A, Maniatis T. Use of a cDNA library for studies on evolution and developmental expression of the chorion multigene families. Cell. 18: 1303-16. PMID 519770 DOI: 10.1016/0092-8674(79)90241-1 |
0.338 |
|
1979 |
Hardison RC, Butler ET, Lacy E, Maniatis T, Rosenthal N, Efstratiadis A. The structure and transcription of four linked rabbit beta-like globin genes. Cell. 18: 1285-97. PMID 519769 DOI: 10.1016/0092-8674(79)90239-3 |
0.582 |
|
1979 |
Lacy E, Hardison RC, Quon D, Maniatis T. The linkage arrangement of four rabbit beta-like globin genes. Cell. 18: 1273-83. PMID 519768 DOI: 10.1016/0092-8674(79)90238-1 |
0.545 |
|
1979 |
Fritsch EF, Lawn RM, Maniatis T. Characterisation of deletions which affect the expression of fetal globin genes in man Nature. 279: 598-603. PMID 450109 DOI: 10.1038/279598a0 |
0.378 |
|
1979 |
Wold B, Wigler M, Lacy E, Maniatis T, Silverstein S, Axel R. Introduction and expression of a rabbit beta-globin gene in mouse fibroblasts. Proceedings of the National Academy of Sciences of the United States of America. 76: 5684-8. PMID 293672 DOI: 10.1073/pnas.76.11.5684 |
0.647 |
|
1979 |
Wigler M, Sweet R, Sim GK, Wold B, Pellicer A, Lacy E, Maniatis T, Silverstein S, Axel R. Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell. 16: 777-85. PMID 222468 DOI: 10.1016/0092-8674(79)90093-X |
0.593 |
|
1978 |
Maniatis T, Hardison RC, Lacy E, Lauer J, O'Connell C, Quon D, Sim GK, Efstratiadis A. The isolation of structural genes from libraries of eucaryotic DNA. Cell. 15: 687-701. PMID 719759 DOI: 10.1016/0092-8674(78)90036-3 |
0.576 |
|
1978 |
Sim GK, Efstratiadis A, Jones CW, Kafatos FC, Koehler M, Kronenberg HM, Maniatis T, Regier JC, Roberts BF, Rosenthal N. Studies on the structure of genes expressed during development. Cold Spring Harbor Symposia On Quantitative Biology. 42: 933-45. PMID 277327 DOI: 10.1101/Sqb.1978.042.01.095 |
0.323 |
|
1978 |
Lawn RM, Fritsch EF, Parker RC, Blake G, Maniatis T. The isolation and characterization of linked δ- and β-globin genes from a cloned library of human DNA Cell. 15: 1157-1174. DOI: 10.1016/0092-8674(78)90043-0 |
0.359 |
|
1977 |
Efstratiadis A, Kafatos FC, Maniatis T. The primary structure of rabbit beta-globin mRNA as determined from cloned DNA. Cell. 10: 571-85. PMID 558827 DOI: 10.1016/0092-8674(77)90090-3 |
0.394 |
|
1976 |
Maniatis T, Ptashne M. A DNA operator-repressor system. Scientific American. 234: 64-6, 71-6. PMID 1251177 DOI: 10.1038/Scientificamerican0176-64 |
0.511 |
|
1976 |
Maniatis T, Kee SG, Efstratiadis A, Kafatos FC. Amplification and characterization of a beta-globin gene synthesized in vitro. Cell. 8: 163-82. PMID 61066 DOI: 10.1016/0092-8674(76)90001-5 |
0.377 |
|
1976 |
Efstratiadis A, Kafatos FC, Maxam AM, Maniatis T. Enzymatic in vitro synthesis of globin genes. Cell. 7: 279-88. PMID 60178 DOI: 10.1016/0092-8674(76)90027-1 |
0.365 |
|
1975 |
Maniatis T, Ptashne M, Backman K, Kield D, Flashman S, Jeffrey A, Maurer R. Recognition sequences of repressor and polymerase in the operators of bacteriophage lambda. Cell. 5: 109-13. PMID 1095210 DOI: 10.1016/0092-8674(75)90018-5 |
0.577 |
|
1975 |
Maniatis T, Jeffrey A, Kleid DG. Nucleotide sequence of the rightward operator of phage lambda. Proceedings of the National Academy of Sciences of the United States of America. 72: 1184-8. PMID 1055375 DOI: 10.1073/PNAS.72.3.1184 |
0.307 |
|
1975 |
Efstratiadis A, Maniatis T, Kafatos FC, Jeffrey A, Vournakis JN. Full length and discrete partial reverse transcripts of globin and chorion mRNAs. Cell. 4: 367-78. PMID 47272 DOI: 10.1016/0092-8674(75)90157-9 |
0.33 |
|
1974 |
Maniatis T, Ptashne M, Barrell BG, Donelson J. Sequence of a repressor-binding site in the DNA of bacteriophage lamda. Nature. 250: 394-7. PMID 4854243 DOI: 10.1038/250394A0 |
0.585 |
|
1974 |
Maurer R, Maniatis T, Ptashne M. Promoters are in the operators in phage lambda. Nature. 249: 221-3. PMID 4598033 DOI: 10.1038/249221A0 |
0.562 |
|
1974 |
Maniatis T, Ptashne M, Maurer R. Control elements in the DNA of bacteriophage lambda. Cold Spring Harbor Symposia On Quantitative Biology. 38: 857-68. PMID 4545512 DOI: 10.1101/Sqb.1974.038.01.088 |
0.52 |
|
1974 |
Maniatis T, Venable JH, Lerman LS. The structure of psi DNA. Journal of Molecular Biology. 84: 37-64. PMID 4208607 DOI: 10.1016/0022-2836(74)90211-3 |
0.628 |
|
1973 |
Maniatis T, Ptashne M. Structure of the lambda operators. Nature. 246: 133-6. PMID 4586104 DOI: 10.1038/246133A0 |
0.554 |
|
1973 |
Maniatis T, Ptashne M. Multiple repressor binding at the operators in bacteriophage lambda. Proceedings of the National Academy of Sciences of the United States of America. 70: 1531-5. PMID 4514322 DOI: 10.1073/Pnas.70.5.1531 |
0.532 |
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