Year |
Citation |
Score |
2024 |
Jiang Y, Kim A, Olive C, Lewis JC. Selective C-H Halogenation of Alkenes and Alkynes Using Flavin-Dependent Halogenases. Angewandte Chemie (International Ed. in English). e202317860. PMID 38280216 DOI: 10.1002/anie.202317860 |
0.442 |
|
2023 |
Mondal D, Snodgrass HM, Gomez CA, Lewis JC. Non-Native Site-Selective Enzyme Catalysis. Chemical Reviews. 123: 10381-10431. PMID 37524057 DOI: 10.1021/acs.chemrev.3c00215 |
0.831 |
|
2023 |
Liu B, Zubi YS, Lewis JC. Iridium(III) polypyridine artificial metalloenzymes with tunable photophysical properties: a new platform for visible light photocatalysis in aqueous solution. Dalton Transactions (Cambridge, England : 2003). 52: 5034-5038. PMID 37060130 DOI: 10.1039/d3dt00932g |
0.335 |
|
2023 |
Jiang Y, Lewis JC. Asymmetric catalysis by flavin-dependent halogenases. Chirality. PMID 36916449 DOI: 10.1002/chir.23550 |
0.438 |
|
2023 |
Gomez CA, Mondal D, Du Q, Chan N, Lewis JC. Directed Evolution of an Iron(II)- and α-Ketoglutarate-Dependent Dioxygenase for Site-Selective Azidation of Unactivated Aliphatic C-H Bonds. Angewandte Chemie (International Ed. in English). PMID 36757808 DOI: 10.1002/anie.202301370 |
0.344 |
|
2022 |
Jiang Y, Mondal D, Lewis JC. Expanding the Reactivity of Flavin Dependent Halogenases Toward Olefins via Enantioselective Intramolecular Haloetherification and Chemoenzymatic Oxidative Rearrangements. Acs Catalysis. 12: 13501-13505. PMID 37377844 DOI: 10.1021/acscatal.2c03383 |
0.382 |
|
2022 |
Andorfer MC, Evans D, Yang S, He CQ, Girlich AM, Vergara-Coll J, Sukumar N, Houk KN, Lewis JC. Analysis of Laboratory-Evolved Flavin-Dependent Halogenases Affords a Computational Model for Predicting Halogenase Site Selectivity. Chem Catalysis. 2: 2658-2674. PMID 36569427 DOI: 10.1016/j.checat.2022.07.003 |
0.785 |
|
2022 |
Jiang Y, Snodgrass HM, Zubi YS, Roof CV, Guan Y, Mondal D, Moneycutt NH, Lee JW, Lewis RD, Martinez CA, Lewis JC. The Single-Component Flavin Reductase/Flavin-Dependent Halogenase AetF is a Versatile Catalyst for Selective Bromination and Iodination of Arenes and Olefins. Angewandte Chemie (International Ed. in English). PMID 36282507 DOI: 10.1002/anie.202214610 |
0.831 |
|
2022 |
Snodgrass HM, Mondal D, Lewis JC. Directed Evolution of Flavin-Dependent Halogenases for Site- and Atroposelective Halogenation of 3-Aryl-4(3)-Quinazolinones via Kinetic or Dynamic Kinetic Resolution. Journal of the American Chemical Society. 144: 16676-16682. PMID 36044712 DOI: 10.1021/jacs.2c07422 |
0.829 |
|
2022 |
Zubi YS, Seki K, Li Y, Hunt AC, Liu B, Roux B, Jewett MC, Lewis JC. Metal-responsive regulation of enzyme catalysis using genetically encoded chemical switches. Nature Communications. 13: 1864. PMID 35387988 DOI: 10.1038/s41467-022-29239-y |
0.54 |
|
2021 |
Yang X, Gerroll BHR, Jiang Y, Kumar A, Zubi YS, Baker LA, Lewis JC. Controlling Non-Native Cobalamin Reactivity and Catalysis in the Transcription Factor CarH. Acs Catalysis. 12: 935-942. PMID 35340760 DOI: 10.1021/acscatal.1c04748 |
0.36 |
|
2021 |
Jones KA, Snodgrass HM, Belsare K, Dickinson BC, Lewis JC. Phage-Assisted Continuous Evolution and Selection of Enzymes for Chemical Synthesis. Acs Central Science. 7: 1581-1590. PMID 34584960 DOI: 10.1021/acscentsci.1c00811 |
0.817 |
|
2021 |
Upp DM, Huang R, Li Y, Bultman MJ, Roux B, Lewis JC. Engineering Dirhodium Artificial Metalloenzymes for Diazo Coupling Cascade Reactions. Angewandte Chemie (International Ed. in English). PMID 34288306 DOI: 10.1002/anie.202107982 |
0.321 |
|
2021 |
Mondal D, Fisher BF, Jiang Y, Lewis JC. Flavin-dependent halogenases catalyze enantioselective olefin halocyclization. Nature Communications. 12: 3268. PMID 34075034 DOI: 10.1038/s41467-021-23503-3 |
0.463 |
|
2020 |
Salazar CA, Gair JJ, Flesch KN, Guzei IA, Lewis JC, Stahl SS. Catalytic Behavior of Mono-N-Protected Amino Acid Ligands in Ligand-Accelerated C-H Activation by Palladium(II). Angewandte Chemie (International Ed. in English). PMID 32196853 DOI: 10.1002/Anie.202002484 |
0.402 |
|
2019 |
Huang R, Chen H, Upp DM, Lewis JC, Job Zhang YP. A High-Throughput Method for Directed Evolution of NAD(P)-Dependent Dehydrogenases for the Reduction of Biomimetic Nicotinamide Analogues. Acs Catalysis. 9: 11709-11719. PMID 34765284 DOI: 10.1021/acscatal.9b03840 |
0.31 |
|
2019 |
Fisher BF, Snodgrass HM, Jones KA, Andorfer MC, Lewis JC. Site-Selective C-H Halogenation Using Flavin-Dependent Halogenases Identified via Family-Wide Activity Profiling. Acs Central Science. 5: 1844-1856. PMID 31807686 DOI: 10.1021/Acscentsci.9B00835 |
0.813 |
|
2019 |
Jones KA, Kentala K, Beck MW, An W, Lippert AR, Lewis JC, Dickinson BC. Development of a Split Esterase for Protein-Protein Interaction-Dependent Small-Molecule Activation. Acs Central Science. 5: 1768-1776. PMID 31807678 DOI: 10.1021/Acscentsci.9B00567 |
0.308 |
|
2019 |
Lewis JC. Beyond the Second Coordination Sphere: Engineering Dirhodium Artificial Metalloenzymes To Enable Protein Control of Transition Metal Catalysis. Accounts of Chemical Research. PMID 30830755 DOI: 10.1021/Acs.Accounts.8B00625 |
0.476 |
|
2019 |
Ellis-Guardiola K, Rui H, Beckner RL, Srivastava P, Sukumar N, Roux B, Lewis JC. Crystal Structure and Conformational Dynamics of Pyrococcus furiosus Prolyl Oligopeptidase. Biochemistry. PMID 30786206 DOI: 10.1021/Acs.Biochem.9B00031 |
0.784 |
|
2019 |
Gair JJ, Haines BE, Filatov AS, Musaev DG, Lewis JC. Di-Palladium Complexes are Active Catalysts for Mono-N-Protected Amino Acid-Accelerated Enantioselective C–H Functionalization Acs Catalysis. 9: 11386-11397. DOI: 10.1021/Acscatal.9B03887 |
0.42 |
|
2019 |
Huang R, Chen H, Upp DM, Lewis JC, Zhang YPJ. A High-Throughput Method for Directed Evolution of NAD(P)+-Dependent Dehydrogenases for the Reduction of Biomimetic Nicotinamide Analogues Acs Catalysis. 9: 11709-11719. DOI: 10.1021/Acscatal.9B03840 |
0.348 |
|
2018 |
Andorfer MC, Lewis JC. Understanding and Improving the Activity of Flavin-Dependent Halogenases via Random and Targeted Mutagenesis. Annual Review of Biochemistry. PMID 29589959 DOI: 10.1146/Annurev-Biochem-062917-012042 |
0.807 |
|
2018 |
Yang H, Swartz AM, Park HJ, Srivastava P, Ellis-Guardiola K, Upp DM, Lee G, Belsare K, Gu Y, Zhang C, Moellering RE, Lewis JC. Evolving artificial metalloenzymes via random mutagenesis. Nature Chemistry. 10: 318-324. PMID 29461523 DOI: 10.1038/Nchem.2927 |
0.809 |
|
2018 |
Payne JT, Butkovich PH, Gu YF, Kunze KN, Park HJ, Wang D, Lewis JC. Enantioselective Desymmetrization of Methylenedianilines via Enzyme-Catalyzed Remote Halogenation. Journal of the American Chemical Society. PMID 29294291 DOI: 10.1021/Jacs.7B09573 |
0.772 |
|
2018 |
Ellis-Guardiola K, Rui H, Beckner R, Srivastava P, Sukumar N, Roux B, Lewis J. Pyrococcus furiosus Prolyl Oligopeptidase: A Dynamic Supramolecular Host for Peptidase and Dirhodium Catalysis Chemrxiv. DOI: 10.26434/Chemrxiv.7053812 |
0.566 |
|
2017 |
Gair JJ, Haines BE, Filatov AS, Musaev DG, Lewis JC. Mono--protected amino acid ligands stabilize dimeric palladium(ii) complexes of importance to C-H functionalization. Chemical Science. 8: 5746-5756. PMID 29619194 DOI: 10.1039/C7Sc01674C |
0.379 |
|
2017 |
Andorfer MC, Grob JE, Hajdin CE, Chael JR, Siuti P, Lilly J, Tan KL, Lewis JC. Understanding Flavin-Dependent Halogenase Reactivity via Substrate Activity Profiling. Acs Catalysis. 7: 1897-1904. PMID 28989809 DOI: 10.1021/Acscatal.6B02707 |
0.824 |
|
2017 |
Andorfer MC, Belsare KD, Girlich AM, Lewis J. Aromatic Halogenation Using Bifunctional Flavin Reductase-Halogenase Fusion Enzymes. Chembiochem : a European Journal of Chemical Biology. PMID 28879681 DOI: 10.1002/Cbic.201700391 |
0.807 |
|
2017 |
Schwizer F, Okamoto Y, Heinisch T, Gu Y, Pellizzoni MM, Lebrun V, Reuter R, Köhler V, Lewis JC, Ward TR. Artificial Metalloenzymes: Reaction Scope and Optimization Strategies. Chemical Reviews. PMID 28714313 DOI: 10.1021/Acs.Chemrev.7B00014 |
0.46 |
|
2017 |
Upp DM, Lewis JC. Selective C-H bond functionalization using repurposed or artificial metalloenzymes. Current Opinion in Chemical Biology. 37: 48-55. PMID 28135654 DOI: 10.1016/J.Cbpa.2016.12.027 |
0.423 |
|
2017 |
Gair JJ, Qiu Y, Chan NH, Filatov AS, Lewis JC. Rhodium Complexes of 2,6-Bis(dialkylphosphinomethyl)pyridines: Improved C–H Activation, Expanded Reaction Scope, and Catalytic Direct Arylation Organometallics. 36: 4699-4706. DOI: 10.1021/Acs.Organomet.7B00532 |
0.395 |
|
2016 |
Belsare KD, Andorfer MC, Cardenas F, Chael JR, Park HJ, Lewis JC. A Simple Combinatorial Codon Mutagenesis Method for Targeted Protein Engineering. Acs Synthetic Biology. PMID 28033708 DOI: 10.1021/Acssynbio.6B00297 |
0.788 |
|
2016 |
Payne JT, Andorfer MC, Lewis JC. Engineering Flavin-Dependent Halogenases. Methods in Enzymology. 575: 93-126. PMID 27417926 DOI: 10.1016/Bs.Mie.2016.03.024 |
0.8 |
|
2016 |
Andorfer MC, Park HJ, Vergara-Coll J, Lewis JC. Directed Evolution of RebH for Catalyst-Controlled Halogenation of Indole C-H Bonds. Chemical Science (Royal Society of Chemistry : 2010). 7: 3720-3729. PMID 27347367 DOI: 10.1039/C5Sc04680G |
0.8 |
|
2016 |
Durak LJ, Payne JT, Lewis JC. Late-Stage Diversification of Biologically Active Molecules via Chemoenzymatic C-H Functionalization. Acs Catalysis. 6: 1451-1454. PMID 27274902 DOI: 10.1021/Acscatal.5B02558 |
0.817 |
|
2016 |
Durak LJ, Payne JT, Lewis JC. Late-Stage Diversification of Biologically Active Molecules via Chemoenzymatic C-H Functionalization Acs Catalysis. 6: 1451-1454. DOI: 10.1021/acscatal.5b02558 |
0.768 |
|
2015 |
Srivastava P, Yang H, Ellis-Guardiola K, Lewis JC. Engineering a dirhodium artificial metalloenzyme for selective olefin cyclopropanation. Nature Communications. 6: 7789. PMID 26206238 DOI: 10.1038/Ncomms8789 |
0.794 |
|
2015 |
Gu Y, Ellis-Guardiola K, Srivastava P, Lewis JC. Preparation, Characterization, and Oxygenase Activity of a Photocatalytic Artificial Enzyme. Chembiochem : a European Journal of Chemical Biology. PMID 26097041 DOI: 10.1002/Cbic.201500165 |
0.809 |
|
2015 |
Payne JT, Poor CB, Lewis JC. Directed evolution of RebH for site-selective halogenation of large biologically active molecules. Angewandte Chemie (International Ed. in English). 54: 4226-30. PMID 25678465 DOI: 10.1002/Anie.201411901 |
0.82 |
|
2015 |
Lewis JC. Metallopeptide catalysts and artificial metalloenzymes containing unnatural amino acids. Current Opinion in Chemical Biology. 25: 27-35. PMID 25545848 DOI: 10.1016/J.Cbpa.2014.12.016 |
0.341 |
|
2014 |
Zhang C, Srivastava P, Ellis-Guardiola K, Lewis JC. Manganese terpyridine artificial metalloenzymes for benzylic oxygenation and olefin epoxidation. Tetrahedron. 70: 4245-4249. PMID 24904188 DOI: 10.1016/J.Tet.2014.03.008 |
0.781 |
|
2014 |
Poor CB, Andorfer MC, Lewis JC. Improving the stability and catalyst lifetime of the halogenase RebH by directed evolution. Chembiochem : a European Journal of Chemical Biology. 15: 1286-9. PMID 24849696 DOI: 10.1002/Cbic.201300780 |
0.808 |
|
2014 |
Yang H, Srivastava P, Zhang C, Lewis JC. A general method for artificial metalloenzyme formation through strain-promoted azide-alkyne cycloaddition. Chembiochem : a European Journal of Chemical Biology. 15: 223-7. PMID 24376040 DOI: 10.1002/Cbic.201300661 |
0.717 |
|
2014 |
Payne JT, Lewis JC. Upgrading nature's tools: Expression enhancement and preparative utility of the halogenase RebH Synlett. 25: 1345-1349. DOI: 10.1055/S-0033-1341024 |
0.711 |
|
2014 |
Durak LJ, Lewis JC. Iridium-promoted, palladium-catalyzed direct arylation of unactivated arenes Organometallics. 33: 620-623. DOI: 10.1021/Om401221V |
0.792 |
|
2014 |
Coelho PS, Arnold FH, Lewis JC. Synthetic Biology Approaches for Organic Synthesis Comprehensive Organic Synthesis: Second Edition. 9: 390-420. DOI: 10.1016/B978-0-08-097742-3.00931-9 |
0.408 |
|
2014 |
Yang H, Srivastava P, Zhang C, Lewis JC. Cover Picture: A General Method for Artificial Metalloenzyme Formation through Strain-Promoted Azide-Alkyne Cycloaddition (ChemBioChem 2/2014) Chembiochem. 15: 173-173. DOI: 10.1002/Cbic.201490000 |
0.644 |
|
2013 |
McIntosh JA, Coelho PS, Farwell CC, Wang ZJ, Lewis JC, Brown TR, Arnold FH. Enantioselective intramolecular C-H amination catalyzed by engineered cytochrome P450 enzymes in vitro and in vivo. Angewandte Chemie (International Ed. in English). 52: 9309-12. PMID 23893546 DOI: 10.1002/Anie.201304401 |
0.802 |
|
2013 |
Payne JT, Andorfer MC, Lewis JC. Regioselective arene halogenation using the FAD-dependent halogenase RebH. Angewandte Chemie (International Ed. in English). 52: 5271-4. PMID 23592388 DOI: 10.1002/Anie.201300762 |
0.819 |
|
2013 |
Durak LJ, Lewis JC. Transmetalation of alkyl ligands from Cp*(PMe3)IrR 1R2 to (cod)PtR3X Organometallics. 32: 3153-3156. DOI: 10.1021/Om400289S |
0.78 |
|
2013 |
Lewis JC. Artificial metalloenzymes and metallopeptide catalysts for organic synthesis Acs Catalysis. 3: 2954-2975. DOI: 10.1021/Cs400806A |
0.374 |
|
2012 |
Zhong Z, Yang H, Zhang C, Lewis JC. Synthesis and Catalytic Activity of Amino Acids and Metallopeptides with Catalytically Active Metallocyclic Side Chains. Organometallics. 31: 7328-7331. PMID 23565022 DOI: 10.1021/Om300848P |
0.502 |
|
2011 |
Lewis JC, Coelho PS, Arnold FH. Enzymatic functionalization of carbon-hydrogen bonds. Chemical Society Reviews. 40: 2003-21. PMID 21079862 DOI: 10.1039/C0Cs00067A |
0.632 |
|
2010 |
Lewis JC, Mantovani SM, Fu Y, Snow CD, Komor RS, Wong CH, Arnold FH. Combinatorial alanine substitution enables rapid optimization of cytochrome P450BM3 for selective hydroxylation of large substrates. Chembiochem : a European Journal of Chemical Biology. 11: 2502-5. PMID 21108271 DOI: 10.1002/Cbic.201000565 |
0.817 |
|
2009 |
Lewis JC, Bastian S, Bennett CS, Fu Y, Mitsuda Y, Chen MM, Greenberg WA, Wong CH, Arnold FH. Chemoenzymatic elaboration of monosaccharides using engineered cytochrome P450BM3 demethylases. Proceedings of the National Academy of Sciences of the United States of America. 106: 16550-5. PMID 19805336 DOI: 10.1073/Pnas.0908954106 |
0.582 |
|
2009 |
Arnold FH, Lewis JC. Catalysts on demand: Selective oxidations by laboratory-evolved cytochrome P450 BM3 Chimia. 63: 309-312. DOI: 10.2533/Chimia.2009.309 |
0.606 |
|
2009 |
Berman AM, Lewis JC, Bergman RG, Ellman JA. ChemInform Abstract: Rh(I)-Catalyzed Direct Arylation of Pyridines and Quinolines. Cheminform. 40. DOI: 10.1002/chin.200912160 |
0.668 |
|
2008 |
Berman AM, Lewis JC, Bergman RG, Ellman JA. Rh(I)-catalyzed direct arylation of pyridines and quinolines. Journal of the American Chemical Society. 130: 14926-7. PMID 18855360 DOI: 10.1021/Ja8059396 |
0.748 |
|
2008 |
Lewis JC, Bergman RG, Ellman JA. Direct functionalization of nitrogen heterocycles via Rh-catalyzed C-H bond activation. Accounts of Chemical Research. 41: 1013-25. PMID 18616300 DOI: 10.1021/Ar800042P |
0.7 |
|
2008 |
Lewis JC, Berman AM, Bergman RG, Ellman JA. Rh(I)-catalyzed arylation of heterocycles via C-H bond activation: expanded scope through mechanistic insight. Journal of the American Chemical Society. 130: 2493-500. PMID 18251465 DOI: 10.1021/Ja0748985 |
0.767 |
|
2008 |
Lewis JC, Bergman RG, Ellman JA. ChemInform Abstract: Direct Functionalization of Nitrogen Heterocycles via Rh-Catalyzed C-H Bond Activation Cheminform. 39. DOI: 10.1002/chin.200848273 |
0.458 |
|
2007 |
Lewis JC, Bergman RG, Ellman JA. Rh(I)-catalyzed alkylation of quinolines and pyridines via C-H bond activation. Journal of the American Chemical Society. 129: 5332-3. PMID 17411050 DOI: 10.1021/Ja070388Z |
0.663 |
|
2007 |
Tanuwidjaja J, Peltier HM, Lewis JC, Schenkel LB, Ellman JA. One-pot microwave-promoted synthesis of nitriles from aldehydes via tert-butanesulfinyl imines Synthesis. 3385-3389. DOI: 10.1055/S-2007-990805 |
0.78 |
|
2006 |
Wiedemann SH, Lewis JC, Ellman JA, Bergman RG. Experimental and computational studies on the mechanism of N-heterocycle C-H activation by Rh(I). Journal of the American Chemical Society. 128: 2452-62. PMID 16478202 DOI: 10.1021/Ja0576684 |
0.797 |
|
2006 |
Lewis JC, Wu JY, Bergman RG, Ellman JA. Microwave-promoted rhodium-catalyzed arylation of heterocycles through C--H bond activation. Angewandte Chemie (International Ed. in English). 45: 1589-91. PMID 16444794 DOI: 10.1002/Anie.200504289 |
0.637 |
|
2006 |
Zhang Y, Lewis JC, Bergman RG, Ellman JA, Oldfield E. NMR shifts, orbitals, and M⋯H-X bonding in d 8 square planar metal complexes Organometallics. 25: 3515-3519. DOI: 10.1021/Om060163H |
0.637 |
|
2005 |
Lewis JC, Wu J, Bergman RG, Ellman JA. Preagostic Rh-H interactions and C-H bond functionalization: A Combined Experimental and Theoretical Investigation of Rhodium (I) Phosphinite Complexes Organometallics. 24: 5737-5746. DOI: 10.1021/Om050700I |
0.599 |
|
2004 |
Souers AJ, Wodka D, Gao J, Lewis JC, Vasudevan A, Brodjian S, Dayton B, Ogiela CA, Fry D, Hernandez LE, Marsh KC, Collins CA, Kym PR. Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 3. Bioorganic & Medicinal Chemistry Letters. 14: 4883-6. PMID 15341944 DOI: 10.1016/J.Bmcl.2004.07.035 |
0.618 |
|
2004 |
Souers AJ, Wodka D, Gao J, Lewis JC, Vasudevan A, Gentles R, Brodjian S, Dayton B, Ogiela CA, Fry D, Hernandez LE, Marsh KC, Collins CA, Kym PR. Synthesis and evaluation of 2-amino-8-alkoxy quinolines as MCHr1 antagonists. Part 1. Bioorganic & Medicinal Chemistry Letters. 14: 4873-7. PMID 15341942 DOI: 10.1016/J.Bmcl.2004.07.032 |
0.603 |
|
2004 |
Lewis JC, Wiedemann SH, Bergman RG, Ellman JA. Arylation of heterocycles via rhodium-catalyzed C-H bond functionalization. Organic Letters. 6: 35-8. PMID 14703344 DOI: 10.1021/Ol035985E |
0.803 |
|
2004 |
Ghosh S, Chan JM, Lea CR, Meints GA, Lewis JC, Tovian ZS, Flessner RM, Loftus TC, Bruchhaus I, Kendrick H, Croft SL, Kemp RG, Kobayashi S, Nozaki T, Oldfield E. Effects of bisphosphonates on the growth of Entamoeba histolytica and Plasmodium species in vitro and in vivo. Journal of Medicinal Chemistry. 47: 175-87. PMID 14695831 DOI: 10.1021/Jm030084X |
0.496 |
|
2002 |
Martin MB, Sanders JM, Kendrick H, de Luca-Fradley K, Lewis JC, Grimley JS, Van Brussel EM, Olsen JR, Meints GA, Burzynska A, Kafarski P, Croft SL, Oldfield E. Activity of bisphosphonates against Trypanosoma brucei rhodesiense. Journal of Medicinal Chemistry. 45: 2904-14. PMID 12086478 DOI: 10.1021/Jm0102809 |
0.474 |
|
2001 |
Martin MB, Grimley JS, Lewis JC, Heath HT, Bailey BN, Kendrick H, Yardley V, Caldera A, Lira R, Urbina JA, Moreno SN, Docampo R, Croft SL, Oldfield E. Bisphosphonates inhibit the growth of Trypanosoma brucei, Trypanosoma cruzi, Leishmania donovani, Toxoplasma gondii, and Plasmodium falciparum: a potential route to chemotherapy. Journal of Medicinal Chemistry. 44: 909-16. PMID 11300872 DOI: 10.1021/Jm0002578 |
0.421 |
|
Show low-probability matches. |