Kenneth G. Mann, PhD - Publications

Affiliations: 
University of Vermont University of Vermont, Burlington, VT, United States 
Area:
Blood Coagulation Biochemistry
Website:
http://biochem.uvm.edu/mann-lab/

236 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Becker RC, Bovill EG, Corrao JM, Ball SP, Ault K, Mann KG, Tracy RP. Dynamic Nature of Thrombin Generation, Fibrin Formation, and Platelet Activation in Unstable Angina and Non-Q-Wave Myocardial Infarction. Journal of Thrombosis and Thrombolysis. 2: 57-64. PMID 10639214 DOI: 10.1007/Bf01063163  0.351
2019 Callas PW, Tracy RP, Bovill EG, Cannon C, Thompson B, Mann KG. The Association of Anticoagulant Protein Concentrations with Acute Myocardial Infarction in the Thromholysis in Myocardial Infarction Phase II (TIMI II) Trial. Journal of Thrombosis and Thrombolysis. 5: 53-60. PMID 10608051 DOI: 10.1023/A:1008866505047  0.303
2019 Becker RC, Bovill EG, Corrao JM, Ball SP, Ault K, Mann K, Tracy RP. Platelet Activation Determined by Flow Cytometry Persists Despite Antithrombotic Therapy in Patients with Unstable Angina and Non-Q-Wave Myocardial Infarction. Journal of Thrombosis and Thrombolysis. 1: 95-100. PMID 10603518 DOI: 10.1007/Bf01062002  0.327
2018 Prior SM, Mann KG, Freeman K, Butenas S. Continuous thrombin generation in whole blood: New applications for assessing activators and inhibitors of coagulation. Analytical Biochemistry. 551: 19-25. PMID 29746819 DOI: 10.1016/J.Ab.2018.05.005  0.375
2017 Bouchard BA, Orfeo T, Keith HN, Lavoie EM, Gissel M, Fung M, Mann KG. Microparticles Formed During Storage of Red Blood Cell Units Support Thrombin Generation. The Journal of Trauma and Acute Care Surgery. PMID 29251713 DOI: 10.1097/Ta.0000000000001759  0.314
2017 Shupp JW, Prior SM, Jo DY, Moffatt LT, Mann KG, Butenas S. Analysis of factor XIa, factor IXa and tissue factor activity in burn patients. Burns : Journal of the International Society For Burn Injuries. PMID 29032977 DOI: 10.1016/J.Burns.2017.08.003  0.387
2017 Haynes LM, Orfeo T, Mann KG, Everse SJ, Brummel-Ziedins KE. Probing the Dynamics of Clot-Bound Thrombin at Venous Shear Rates. Biophysical Journal. 112: 1634-1644. PMID 28445754 DOI: 10.1016/J.Bpj.2017.03.002  0.31
2016 Whelihan MF, Lim MY, Mooberry MJ, Piegore MG, Ilich A, Wogu A, Cai J, Monroe DM, Ataga KI, Mann KG, Key NS. Thrombin generation and cell-dependent hypercoagulability in sickle cell disease. Journal of Thrombosis and Haemostasis : Jth. PMID 27430959 DOI: 10.1111/Jth.13416  0.331
2016 Orfeo T, Elsman R, Gissel M, Mann KG, Butenas S. Activation, activity and inactivation of factor VIII in factor VIII products. Haemophilia : the Official Journal of the World Federation of Hemophilia. PMID 26822998 DOI: 10.1111/Hae.12872  0.359
2016 Prior SM, Mann KG, Freeman K, Butenas S. Continuous Thrombin Generation in Whole Blood: New Applications Blood. 128: 4979-4979. DOI: 10.1182/Blood.V128.22.4979.4979  0.375
2015 Mann KG, Freeman K. TACTIC: Trans-Agency Consortium for Trauma-Induced Coagulopathy. Journal of Thrombosis and Haemostasis : Jth. 13: S63-71. PMID 26149052 DOI: 10.1111/Jth.12981  0.338
2015 Butenas S, Mann KG. The effect of corn trypsin inhibitor and inhibiting antibodies for FXIa and FXIIa on coagulation of plasma and whole blood: comment. Journal of Thrombosis and Haemostasis : Jth. 13: 487-8. PMID 25523109 DOI: 10.1111/Jth.12812  0.328
2014 Undas A, Brummel-Ziedins K, Mann KG. Why does aspirin decrease the risk of venous thromboembolism? On old and novel antithrombotic effects of acetyl salicylic acid. Journal of Thrombosis and Haemostasis : Jth. 12: 1776-87. PMID 25213262 DOI: 10.1111/Jth.12728  0.336
2014 Aledort L, Ljung R, Mann K, Pipe S. Factor VIII therapy for hemophilia A: current and future issues. Expert Review of Hematology. 7: 373-85. PMID 24717090 DOI: 10.1586/17474086.2014.899896  0.308
2014 Bouchard BA, Gissel MT, Whelihan MF, Mann KG, Butenas S. Platelets do not express the oxidized or reduced forms of tissue factor. Biochimica Et Biophysica Acta. 1840: 1188-93. PMID 24361609 DOI: 10.1016/J.Bbagen.2013.11.024  0.368
2014 Brummel-Ziedins KE, Everse SJ, Mann KG, Orfeo T. Modeling thrombin generation: plasma composition based approach. Journal of Thrombosis and Thrombolysis. 37: 32-44. PMID 24214371 DOI: 10.1007/S11239-013-1006-9  0.322
2014 Whelihan MF, Lim MY, Walton BL, Wolberg AS, Cai J, Ataga KI, Mann KG, Key NS. Hypercoagulability in Sickle Cell Disease: The Importance of the Cellular Component of Blood Blood. 124: 4060-4060. DOI: 10.1182/Blood.V124.21.4060.4060  0.319
2014 Cohen MJ, Orfeo T, Howard B, Korrnblith L, Conroy A, Gissel M, Brummel-Ziedins KE, Mann KG. Trauma and Hemorrhage: Functional Characterization of Acute Traumatic Coagulopathy Blood. 124: 1516-1516. DOI: 10.1182/Blood.V124.21.1516.1516  0.344
2014 Bravo MC, Orfeo T, Lavoie E, Dubief Y, Mann KG. Analysis of the Protein C System Under Flow and the Impact of Red Blood Cells Blood. 124: 1480-1480. DOI: 10.1182/Blood.V124.21.1480.1480  0.352
2013 Whelihan MF, Mooberry MJ, Zachary V, Bradford RL, Ataga KI, Mann KG, Key NS. The contribution of red blood cells to thrombin generation in sickle cell disease: meizothrombin generation on sickled red blood cells. Journal of Thrombosis and Haemostasis : Jth. 11: 2187-9. PMID 24119168 DOI: 10.1111/Jth.12423  0.351
2012 Mann KG. Is there value in kinetic modeling of thrombin generation? Yes. Journal of Thrombosis and Haemostasis : Jth. 10: 1463-9. PMID 22642417 DOI: 10.1111/J.1538-7836.2012.04799.X  0.329
2012 Mann KG, Krudysz-Amblo J, Butenas S. Tissue factor controversies. Thrombosis Research. 129: S5-7. PMID 22401799 DOI: 10.1016/J.Thromres.2012.02.018  0.363
2012 Danforth CM, Orfeo T, Everse SJ, Mann KG, Brummel-Ziedins KE. Defining the boundaries of normal thrombin generation: investigations into hemostasis. Plos One. 7: e30385. PMID 22319567 DOI: 10.1371/Journal.Pone.0030385  0.37
2012 Foley JH, Butenas S, Mann KG, Brummel-Ziedins KE. Measuring the mechanical properties of blood clots formed via the tissue factor pathway of coagulation. Analytical Biochemistry. 422: 46-51. PMID 22266209 DOI: 10.1016/J.Ab.2011.12.036  0.375
2012 Brummel-Ziedins KE, Orfeo T, Gissel M, Mann KG, Rosendaal FR. Factor Xa generation by computational modeling: an additional discriminator to thrombin generation evaluation. Plos One. 7: e29178. PMID 22247769 DOI: 10.1371/Journal.Pone.0029178  0.351
2012 Butenas S, Amblo-Krudysz J, Mann KG. Posttranslational modifications of tissue factor. Frontiers in Bioscience (Elite Edition). 4: 381-91. PMID 22201880 DOI: 10.2741/385  0.381
2012 Gissel M, Whelihan MF, Ferris LA, Mann KG, Rivard GE, Brummel-Ziedins KE. The influence of prophylactic factor VIII in severe haemophilia A. Haemophilia : the Official Journal of the World Federation of Hemophilia. 18: 193-9. PMID 21899664 DOI: 10.1111/J.1365-2516.2011.02638.X  0.394
2012 Undas A, Slowik A, Gissel M, Mann KG, Butenas S. Active tissue factor and activated factor XI in patients with acute ischemic cerebrovascular events. European Journal of Clinical Investigation. 42: 123-9. PMID 21707613 DOI: 10.1111/J.1365-2362.2011.02565.X  0.322
2012 Mann KG, Krudysz-Amblo J, Butenas S. Erratum to "Tissue factor controversies" [Thrombosis Research 129 (2012) S5–S7] Thrombosis Research. 130: 287. DOI: 10.1016/J.Thromres.2012.05.027  0.302
2011 Orfeo T, Gissel M, Butenas S, Undas A, Brummel-Ziedins KE, Mann KG. Anticoagulants and the propagation phase of thrombin generation. Plos One. 6: e27852. PMID 22125631 DOI: 10.1371/Journal.Pone.0027852  0.359
2011 Rizoli SB, Scarpelini S, Callum J, Nascimento B, Mann KG, Pinto R, Jansen J, Tien HC. Clotting factor deficiency in early trauma-associated coagulopathy. The Journal of Trauma. 71: S427-34. PMID 22071999 DOI: 10.1097/Ta.0B013E318232E5Ab  0.324
2011 Undas A, Slowik A, Gissel M, Mann KG, Butenas S. Circulating activated factor XI and active tissue factor as predictors of worse prognosis in patients following ischemic cerebrovascular events. Thrombosis Research. 128: e62-6. PMID 21820158 DOI: 10.1016/J.Thromres.2011.06.010  0.316
2011 Krudysz-Amblo J, Jennings ME, Matthews DE, Mann KG, Butenas S. Differences in the fractional abundances of carbohydrates of natural and recombinant human tissue factor. Biochimica Et Biophysica Acta. 1810: 398-405. PMID 21172408 DOI: 10.1016/J.Bbagen.2010.12.003  0.396
2011 Whelihan M, Mann KG. Erythrocyte Participation in Thrombin Generation Blood. 118: 374-374. DOI: 10.1182/Blood.V118.21.374.374  0.372
2011 Orfeo T, Gissel M, Whelihan M, Butenas S, Mann KG. Factor XI Activation In Tissue Factor-Initiated Blood Coagulation Blood. 118: 2239-2239. DOI: 10.1182/Blood.V118.21.2239.2239  0.39
2010 Campbell JE, Brummel-Ziedins KE, Butenas S, Mann KG. Cellular regulation of blood coagulation: a model for venous stasis. Blood. 116: 6082-91. PMID 20864579 DOI: 10.1182/Blood-2010-01-266395  0.34
2010 Gissel M, Undas A, Slowik A, Mann KG, Brummel-Ziedins KE. Plasma factor and inhibitor composition contributes to thrombin generation dynamics in patients with acute or previous cerebrovascular events. Thrombosis Research. 126: 262-9. PMID 20709367 DOI: 10.1016/J.Thromres.2010.07.002  0.327
2010 Bouchard BA, Mann KG, Butenas S. No evidence for tissue factor on platelets. Blood. 116: 854-5. PMID 20688968 DOI: 10.1182/Blood-2010-05-285627  0.392
2010 Undas A, Gissel M, Kwasny-Krochin B, Gluszko P, Mann KG, Brummel-Ziedins KE. Thrombin generation in rheumatoid arthritis: dependence on plasma factor composition. Thrombosis and Haemostasis. 104: 224-30. PMID 20593110 DOI: 10.1160/Th10-02-0091  0.322
2010 Orfeo T, Butenas S, Brummel-Ziedins KE, Gissel M, Mann KG. Anticoagulation by factor Xa inhibitors. Journal of Thrombosis and Haemostasis : Jth. 8: 1745-53. PMID 20492473 DOI: 10.1111/J.1538-7836.2010.03917.X  0.349
2010 Whelihan MF, Orfeo T, Gissel MT, Mann KG. Coagulation procofactor activation by factor XIa. Journal of Thrombosis and Haemostasis : Jth. 8: 1532-9. PMID 20456758 DOI: 10.1111/J.1538-7836.2010.03899.X  0.373
2010 Butenas S, Parhami-Seren B, Undas A, Fass DN, Mann KG. The "normal" factor VIII concentration in plasma. Thrombosis Research. 126: 119-23. PMID 20451961 DOI: 10.1016/J.Thromres.2010.04.004  0.342
2010 Butenas S, Krudysz-Amblo J, Mann KG. Posttranslational modifications and activity of natural and recombinant tissue factor. Thrombosis Research. 125: S26-8. PMID 20138335 DOI: 10.1016/J.Thromres.2010.01.028  0.391
2010 Undas A, Owczarek D, Gissel M, Salapa K, Mann KG, Butenas S. Activated factor XI and tissue factor in inflammatory bowel disease. Inflammatory Bowel Diseases. 16: 1447-8. PMID 20049947 DOI: 10.1002/Ibd.21206  0.343
2010 Krudysz-Amblo J, Jennings ME, Mann KG, Butenas S. Carbohydrates and activity of natural and recombinant tissue factor. The Journal of Biological Chemistry. 285: 3371-82. PMID 19955571 DOI: 10.1074/Jbc.M109.055178  0.363
2009 Park MS, Martini WZ, Dubick MA, Salinas J, Butenas S, Kheirabadi BS, Pusateri AE, Vos JA, Guymon CH, Wolf SE, Mann KG, Holcomb JB. Thromboelastography as a better indicator of hypercoagulable state after injury than prothrombin time or activated partial thromboplastin time. The Journal of Trauma. 67: 266-75; discussion 2. PMID 19667878 DOI: 10.1097/Ta.0B013E3181Ae6F1C  0.305
2009 Brummel-Ziedins KE, Orfeo T, Rosendaal FR, Undas A, Rivard GE, Butenas S, Mann KG. Empirical and theoretical phenotypic discrimination. Journal of Thrombosis and Haemostasis : Jth. 7: 181-6. PMID 19630796 DOI: 10.1111/J.1538-7836.2009.03426.X  0.321
2009 Butenas S, Orfeo T, Mann KG. Tissue factor in coagulation: Which? Where? When? Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1989-96. PMID 19592470 DOI: 10.1161/Atvbaha.108.177402  0.377
2009 Brummel-Ziedins KE, Whelihan MF, Gissel M, Mann KG, Rivard GE. Thrombin generation and bleeding in haemophilia A. Haemophilia : the Official Journal of the World Federation of Hemophilia. 15: 1118-25. PMID 19563500 DOI: 10.1111/J.1365-2516.2009.01994.X  0.356
2009 Brummel-Ziedins KE, Gissel M, Francis C, Queenan J, Mann KG. The effect of high circulating estradiol levels on thrombin generation during in vitro fertilization. Thrombosis Research. 124: 505-7. PMID 19297011 DOI: 10.1016/J.Thromres.2009.02.006  0.376
2009 Brummel-Ziedins KE, Branda RF, Butenas S, Mann KG. Discordant fibrin formation in hemophilia. Journal of Thrombosis and Haemostasis : Jth. 7: 825-32. PMID 19192107 DOI: 10.1111/J.1538-7836.2009.03306.X  0.341
2009 Mann KG, Orfeo T, Butenas S, Undas A, Brummel-Ziedins K. Blood coagulation dynamics in haemostasis. HäMostaseologie. 29: 7-16. PMID 19151839 DOI: 10.1055/S-0037-1616932  0.378
2009 Krudysz-Amblo J, Parhami-Seren B, Butenas S, Brummel-Ziedins KE, Gomperts ED, Rivard GE, Mann KG. Quantitation of anti-factor VIII antibodies in human plasma. Blood. 113: 2587-94. PMID 19144987 DOI: 10.1182/Blood-2008-08-174987  0.303
2009 Butenas S, Parhami-Seren B, Mann KG. The influence of von Willebrand factor on factor VIII activity measurements. Journal of Thrombosis and Haemostasis : Jth. 7: 132-7. PMID 18983499 DOI: 10.1111/J.1538-7836.2008.03210.X  0.397
2009 Undas A, Szu?drzy?ski K, Brummel-Ziedins KE, Tracz W, Zmudka K, Mann KG. Systemic blood coagulation activation in acute coronary syndromes. Blood. 113: 2070-8. PMID 18931343 DOI: 10.1182/Blood-2008-07-167411  0.35
2009 Butenas S, Parhami-Seren B, Gissel MT, Gomperts ED, Fass DN, Mann KG. Potency and mass of factor VIII in FVIII products. Haemophilia : the Official Journal of the World Federation of Hemophilia. 15: 63-72. PMID 18691375 DOI: 10.1111/J.1365-2516.2008.01826.X  0.339
2008 Butenas S, Orfeo T, Mann KG. Tissue factor activity and function in blood coagulation. Thrombosis Research. 122: S42-6. PMID 18691499 DOI: 10.1016/S0049-3848(08)70018-5  0.371
2008 Orfeo T, Brummel-Ziedins KE, Gissel M, Butenas S, Mann KG. The nature of the stable blood clot procoagulant activities. The Journal of Biological Chemistry. 283: 9776-86. PMID 18268016 DOI: 10.1074/Jbc.M707435200  0.388
2008 Butenas S, Undas A, Gissel MT, Szuldrzynski K, Zmudka K, Mann KG. Factor XIa and tissue factor activity in patients with coronary artery disease. Thrombosis and Haemostasis. 99: 142-9. PMID 18217146 DOI: 10.1160/Th07-08-0499  0.315
2008 Brummel-Ziedins K, Undas A, Orfeo T, Gissel M, Butenas S, Zmudka K, Mann KG. Thrombin generation in acute coronary syndrome and stable coronary artery disease: dependence on plasma factor composition. Journal of Thrombosis and Haemostasis : Jth. 6: 104-10. PMID 17944993 DOI: 10.1111/J.1538-7836.2007.02799.X  0.319
2008 Everse SJ, Orfeo T, Brummel-Ziedins KE, Hockin MF, Mann KG. Predicting Thrombosis in Factor VLeiden Heterozygotes. Blood. 112: 1818-1818. DOI: 10.1182/Blood.V112.11.1818.1818  0.403
2008 Whelihan MF, Mann KG. Plasma Procofactor Activation by Factor Xla Blood. 112: 1024-1024. DOI: 10.1182/Blood.V112.11.1024.1024  0.34
2008 Butenas S, Parhami-Seren B, Gissel MT, Amblo J, Brummel-Ziedins KE, Mann KG. The Nature of LPS-Stimulated Monocyte Tissue Factor Activity Blood. 112: 1022-1022. DOI: 10.1182/Blood.V112.11.1022.1022  0.324
2008 Giles AR, Mann KG, Nesheim ME. A combination of factor Xa and phosphatidylcholine-phosphatidylserine vesicles bypasses factor VIII in vivo British Journal of Haematology. 69: 491-497. DOI: 10.1111/J.1365-2141.1988.00483.X-I1  0.417
2007 Butenas S, Orfeo T, Brummel-Ziedins KE, Mann KG. Tissue factor in thrombosis and hemorrhage. Surgery. 142: S2-14. PMID 18019946 DOI: 10.1016/J.Surg.2007.06.032  0.373
2007 Undas A, Brzezinska-Kolarz B, Orfeo T, Brummel-Ziedins K, Musial J, Szczeklik A, Mann KG. Blood coagulation at the site of microvascular injury in healthy and coumadin-treated subjects heterogenous for factor V Leiden mutation. Thrombosis and Haemostasis. 98: 1024-30. PMID 18000607 DOI: 10.1160/Th07-04-0302  0.363
2007 Erdogan E, Bukys MA, Orfeo T, Mann KG, Kalafatis M. Identification of an inactivating cleavage site for alpha-thrombin on the heavy chain of factor Va. Thrombosis and Haemostasis. 98: 998-1006. PMID 18000604 DOI: 10.1160/Th07-06-0431  0.305
2007 Mann KG, Whelihan MF, Butenas S, Orfeo T. Citrate anticoagulation and the dynamics of thrombin generation. Journal of Thrombosis and Haemostasis : Jth. 5: 2055-61. PMID 17883701 DOI: 10.1111/J.1538-7836.2007.02710.X  0.36
2007 Butenas S, Orfeo T, Brummel-Ziedins KE, Mann KG. Influence of bivalirudin on tissue factor-triggered coagulation. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 18: 407-14. PMID 17581314 DOI: 10.1097/Mbc.0B013E32814Fcdb8  0.368
2007 Undas A, Brummel-Ziedins KE, Mann KG. Antithrombotic properties of aspirin and resistance to aspirin: beyond strictly antiplatelet actions. Blood. 109: 2285-92. PMID 17148593 DOI: 10.1182/Blood-2006-01-010645  0.337
2006 Brummel-Ziedins K, Whelihan MF, Ziedins EG, Mann KG. The resuscitative fluid you choose may potentiate bleeding. The Journal of Trauma. 61: 1350-8. PMID 17159676 DOI: 10.1182/Blood.V104.11.1029.1029  0.378
2006 Butenas S, Orfeo T, Kalafatis M, Mann KG. Peptidomimetic inhibitors for activated protein C: implications for hemophilia management. Journal of Thrombosis and Haemostasis : Jth. 4: 2411-6. PMID 17059471 DOI: 10.1111/J.1538-7836.2006.02226.X  0.362
2006 Parhami-Seren B, Butenas S, Krudysz-Amblo J, Mann KG. Immunologic quantitation of tissue factors. Journal of Thrombosis and Haemostasis : Jth. 4: 1747-55. PMID 16879217 DOI: 10.1111/J.1538-7836.2006.02000.X  0.338
2006 Mann KG, Brummel-Ziedins K, Orfeo T, Butenas S. Models of blood coagulation. Blood Cells, Molecules & Diseases. 36: 108-17. PMID 16500122 DOI: 10.1097/00001721-200004001-00003  0.355
2006 Erdogan E, Bukys MA, Orfeo T, Mann KG, Kalafatis M. Cleavage of Factor Va Heavy Chain at Arg643 by Thrombin Partially Inactivates the Cofactor. Blood. 108: 1703-1703. DOI: 10.1182/Blood.V108.11.1703.1703  0.441
2006 Mann KG, Whelihan MF, Cooley RB, Orfeo T. Citrate Blood a Century of Artifact. Blood. 108: 1605-1605. DOI: 10.1182/Blood.V108.11.1605.1605  0.354
2005 Orfeo T, Mann KG. Mathematical and biological models of blood coagulation. Journal of Thrombosis and Haemostasis : Jth. 3: 2397-8. PMID 16241937 DOI: 10.1111/J.1538-7836.2005.01592.X  0.423
2005 Orfeo T, Butenas S, Brummel-Ziedins KE, Mann KG. The tissue factor requirement in blood coagulation. The Journal of Biological Chemistry. 280: 42887-96. PMID 16215234 DOI: 10.1074/Jbc.M505506200  0.364
2005 Mann KG. Analyses of protein S function. Blood. 106: 1884; author reply 1. PMID 16113232 DOI: 10.1182/Blood-2004-12-4706  0.302
2005 Rivard GE, Brummel-Ziedins KE, Mann KG, Fan L, Hofer A, Cohen E. Evaluation of the profile of thrombin generation during the process of whole blood clotting as assessed by thrombelastography. Journal of Thrombosis and Haemostasis : Jth. 3: 2039-43. PMID 16102110 DOI: 10.1111/J.1538-7836.2005.01513.X  0.329
2005 Undas A, Brzezinska-Kolarz B, Brummel-Ziedins K, Musial J, Szczeklik A, Mann KG. Factor XIII Val34Leu polymorphism and gamma-chain cross-linking at the site of microvascular injury in healthy and coumadin-treated subjects. Journal of Thrombosis and Haemostasis : Jth. 3: 2015-21. PMID 16102108 DOI: 10.1111/J.1538-7836.2005.01509.X  0.323
2005 Undas A, Celinska-Löwenhoff M, Brummel-Ziedins KE, Brozek J, Szczeklik A, Mann KG. Simvastatin given for 3 days can inhibit thrombin generation and activation of factor V and enhance factor Va inactivation in hypercholesterolemic patients. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 1524-5. PMID 15980269 DOI: 10.1161/01.Atv.0000168913.25278.38  0.366
2005 Brummel-Ziedins K, Vossen CY, Rosendaal FR, Umezaki K, Mann KG. The plasma hemostatic proteome: thrombin generation in healthy individuals. Journal of Thrombosis and Haemostasis : Jth. 3: 1472-81. PMID 15978105 DOI: 10.1111/J.1538-7836.2005.01249.X  0.359
2005 Butenas S, Bouchard BA, Brummel-Ziedins KE, Parhami-Seren B, Mann KG. Tissue factor activity in whole blood. Blood. 105: 2764-70. PMID 15604222 DOI: 10.1182/Blood-2004-09-3567  0.402
2005 Undas A, Brummel-Ziedins KE, Mann KG. Statins and blood coagulation. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 287-94. PMID 15569822 DOI: 10.1161/01.Atv.0000151647.14923.Ec  0.352
2005 Brummel-Ziedins KE, Branda RF, Butenas S, Mann KG. Hemophilia and the Dynamics of Hemostasis. Blood. 106: 321-321. DOI: 10.1182/Blood.V106.11.321.321  0.341
2005 Kalafatis M, Chiott RE, Branda RF, Mann KG. Activated Protein C-Resistance Induced by a Low Molecular Weight Inhibitor. Blood. 106: 2136-2136. DOI: 10.1182/Blood.V106.11.2136.2136  0.376
2004 Butenas S, Mann KG. Active tissue factor in blood? Nature Medicine. 10: 1155-6; author reply. PMID 15516902 DOI: 10.1038/Nm1104-1155B  0.412
2004 Brummel Ziedins K, Rivard GE, Pouliot RL, Butenas S, Gissel M, Parhami-Seren B, Mann KG. Factor VIIa replacement therapy in factor VII deficiency. Journal of Thrombosis and Haemostasis : Jth. 2: 1735-44. PMID 15456484 DOI: 10.1111/J.1538-7836.2004.00922.X  0.359
2004 Mann KG, Brummel-Ziedins K, Undas A, Butenas S. Does the genotype predict the phenotype? Evaluations of the hemostatic proteome. Journal of Thrombosis and Haemostasis : Jth. 2: 1727-34. PMID 15456483 DOI: 10.1111/J.1538-7836.2004.00958.X  0.349
2004 Adams TE, Hockin MF, Mann KG, Everse SJ. The crystal structure of activated protein C-inactivated bovine factor Va: Implications for cofactor function. Proceedings of the National Academy of Sciences of the United States of America. 101: 8918-23. PMID 15184653 DOI: 10.1073/Pnas.0403072101  0.368
2004 Lundblad RL, Bradshaw RA, Gabriel D, Ortel TL, Lawson J, Mann KG. A review of the therapeutic uses of thrombin. Thrombosis and Haemostasis. 91: 851-60. PMID 15116244 DOI: 10.1160/Th03-12-0792  0.385
2004 Butenas S, Orfeo T, Gissel MT, Brummel KE, Mann KG. The significance of circulating factor IXa in blood. The Journal of Biological Chemistry. 279: 22875-82. PMID 15039440 DOI: 10.1074/Jbc.M400531200  0.429
2004 Brummel-Ziedins KE, Pouliot RL, Mann KG. Thrombin generation: phenotypic quantitation. Journal of Thrombosis and Haemostasis : Jth. 2: 281-8. PMID 14995991 DOI: 10.1046/J.1538-7933.2003.00576.X  0.41
2004 Orfeo T, Brufatto N, Nesheim ME, Xu H, Butenas S, Mann KG. The factor V activation paradox. The Journal of Biological Chemistry. 279: 19580-91. PMID 14982929 DOI: 10.1074/Jbc.M400727200  0.429
2004 Butenas S, Parhami-Seren B, Gissel MT, Gomperts ED, Mann KG. Quantitative Evaluation of Factor VIII in Factor VIII Products. Blood. 104: 4012-4012. DOI: 10.1182/Blood.V104.11.4012.4012  0.407
2004 Butenas S, Gissel MT, Bouchard BA, Brummel KE, Parhami-Seren B, Mann KG. Demystifying Tissue Factor. Blood. 104: 1936-1936. DOI: 10.1182/Blood.V104.11.1936.1936  0.412
2004 Parhami-Seren B, Butenas S, Bouchard B, Amblo J, Mann KG. Quantitation of Natural, Recombinant, Cell-Surface and Plasma Tissue Factor. Blood. 104: 1929-1929. DOI: 10.1182/Blood.V104.11.1929.1929  0.36
2004 Butenas S, Orfeo T, Brummel-Ziedins KE, Mann KG. Membrane-Bound and Soluble Tissue Factor - Fuse and Fire Extinguisher. Blood. 104: 123-123. DOI: 10.1182/Blood.V104.11.123.123  0.424
2003 Butenas S, Dee JD, Mann KG. The function of factor XI in tissue factor-initiated thrombin generation. Journal of Thrombosis and Haemostasis : Jth. 1: 2103-11. PMID 14521591 DOI: 10.1046/J.1538-7836.2003.00431.X  0.395
2003 Jenny RJ, Mann KG, Lundblad RL. A critical review of the methods for cleavage of fusion proteins with thrombin and factor Xa. Protein Expression and Purification. 31: 1-11. PMID 12963335 DOI: 10.1016/S1046-5928(03)00168-2  0.307
2003 Adams TE, Everse SJ, Mann KG. Predicting the pharmacology of thrombin inhibitors. Journal of Thrombosis and Haemostasis : Jth. 1: 1024-7. PMID 12871372 DOI: 10.1046/J.1538-7836.2003.00127.X  0.304
2003 Butenas S, Brummel KE, Bouchard BA, Mann KG. How factor VIIa works in hemophilia Journal of Thrombosis and Haemostasis. 1: 1158-1160. PMID 12871314 DOI: 10.1046/J.1538-7836.2003.00181.X  0.384
2003 Mann KG, Brummel K, Butenas S. What is all that thrombin for? Journal of Thrombosis and Haemostasis : Jth. 1: 1504-14. PMID 12871286 DOI: 10.1046/J.1538-7836.2003.00298.X  0.327
2003 Kalafatis M, Beck DO, Mann KG. Structural requirements for expression of factor Va activity. The Journal of Biological Chemistry. 278: 33550-61. PMID 12788947 DOI: 10.1074/Jbc.M303153200  0.403
2003 Mann KG. Factor VII-activating protease: coagulation, fibrinolysis, and atherothrombosis? Circulation. 107: 654-5. PMID 12578860 DOI: 10.1161/01.Cir.0000057382.68508.3D  0.324
2003 Butenas S, Brummel KE, Paradis SG, Mann KG. Influence of factor VIIa and phospholipids on coagulation in "acquired" hemophilia. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 123-9. PMID 12524235 DOI: 10.1161/01.Atv.0000042081.57854.A2  0.401
2003 Mann KG, Butenas S, Brummel K. The dynamics of thrombin formation. Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 17-25. PMID 12524220 DOI: 10.1161/01.Atv.0000046238.23903.Fc  0.33
2003 Undas A, Sydor WJ, Brummel K, Musial J, Mann KG, Szczeklik A. Aspirin alters the cardioprotective effects of the factor XIII Val34Leu polymorphism. Circulation. 107: 17-20. PMID 12515735 DOI: 10.1161/01.Cir.0000047062.03282.A3  0.323
2003 Mann KG, Kalafatis M. Factor V: a combination of Dr Jekyll and Mr Hyde. Blood. 101: 20-30. PMID 12393635 DOI: 10.1182/Blood-2002-01-0290  0.37
2003 Mann KG, Butenas S. Response: Mechanism of Action of High-Dose Factor VIIa Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 10-10. DOI: 10.1161/01.Atv.0000047646.64969.8B  0.378
2002 Brummel KE, Paradis SG, Butenas S, Mann KG. Thrombin functions during tissue factor-induced blood coagulation. Blood. 100: 148-52. PMID 12070020 DOI: 10.1182/Blood.V100.1.148  0.396
2002 Hockin MF, Jones KC, Everse SJ, Mann KG. A model for the stoichiometric regulation of blood coagulation. The Journal of Biological Chemistry. 277: 18322-33. PMID 11893748 DOI: 10.1074/Jbc.M201173200  0.438
2002 Butenas S, Mann KG. Blood coagulation. Biochemistry. Biokhimiia. 67: 3-12. PMID 11841335 DOI: 10.1023/A:1013985911759  0.307
2002 Butenas S, Brummel KE, Branda RF, Paradis SG, Mann KG. Mechanism of factor VIIa-dependent coagulation in hemophilia blood. Blood. 99: 923-30. PMID 11806995 DOI: 10.1182/Blood.V99.3.923  0.411
2002 Kalafatis M, Mann KG. Factor V: Dr. Jeckyll and Mr. Hyde. Advances in Experimental Medicine and Biology. 489: 31-43. PMID 11554589 DOI: 10.1007/978-1-4615-1277-6_3  0.423
2001 Brummel KE, Paradis SG, Branda RF, Mann KG. Oral anticoagulation thresholds Circulation. 104: 2311-2317. PMID 11696471 DOI: 10.1161/Hc4401.098492  0.338
2001 Undas A, Brummel K, Musial J, Mann KG, Szczeklik A. Blood coagulation at the site of microvascular injury: effects of low-dose aspirin. Blood. 98: 2423-31. PMID 11588039 DOI: 10.1182/Blood.V98.8.2423  0.34
2001 Undas A, Brummel KE, Musial J, Mann KG, Szczeklik A. Simvastatin depresses blood clotting by inhibiting activation of prothrombin, factor V, and factor XIII and by enhancing factor Va inactivation. Circulation. 103: 2248-53. PMID 11342472 DOI: 10.1161/01.Cir.103.18.2248  0.369
2001 Butenas S, Cawthern KM, van't Veer C, DiLorenzo ME, Lock JB, Mann KG. Antiplatelet agents in tissue factor-induced blood coagulation. Blood. 97: 2314-22. PMID 11290593 DOI: 10.1182/Blood.V97.8.2314  0.388
2001 Kalafatis M, Mann KG. The role of the membrane in the inactivation of factor va by plasmin. Amino acid region 307-348 of factor V plays a critical role in factor Va cofactor function. The Journal of Biological Chemistry. 276: 18614-23. PMID 11278331 DOI: 10.1074/Jbc.M007134200  0.375
2001 van't Veer C, Mann KG. The regulation of the factor VII-dependent coagulation pathway: rationale for the effectiveness of recombinant factor VIIa in refractory bleeding disorders. Seminars in Thrombosis and Hemostasis. 26: 367-72. PMID 11092210 DOI: 10.1055/S-2000-8454  0.42
2001 Undas A, Williams EB, Butenas S, Orfeo T, Mann KG. Homocysteine inhibits inactivation of factor Va by activated protein C. The Journal of Biological Chemistry. 276: 4389-97. PMID 11083858 DOI: 10.1074/Jbc.M004124200  0.423
2001 Butenas S, Branda R, van ’t Veer C, Cawthern K, Mann K. Platelets and Phospholipids in Tissue Factor-initiated Thrombin Generation Thrombosis and Haemostasis. 86: 660-667. DOI: 10.1055/S-0037-1616110  0.357
2000 Holmes MB, Schneider DJ, Hayes MG, Sobel BE, Mann KG. Novel, bedside, tissue factor-dependent clotting assay permits improved assessment of combination antithrombotic and antiplatelet therapy. Circulation. 102: 2051-7. PMID 11044419 DOI: 10.1161/01.Cir.102.17.2051  0.321
2000 van 't Veer C, Golden NJ, Mann KG. Inhibition of thrombin generation by the zymogen factor VII: implications for the treatment of hemophilia A by factor VIIa Blood. 95: 1330-1335. DOI: 10.1182/Blood.V95.4.1330.004K28_1330_1335  0.382
2000 Kingdon H, Mann K, White G, Lundblad R. Issues with the Assay of Factor VIII Activity in Plasma and Factor VIII Concentrates Thrombosis and Haemostasis. 84: 942-948. DOI: 10.1055/S-0037-1614153  0.406
2000 Mann K. How Much Factor V Is Enough? Thrombosis and Haemostasis. 83: 3-4. DOI: 10.1055/S-0037-1613746  0.314
1999 Brummel KE, Butenas S, Mann KG. An integrated study of fibrinogen during blood coagulation. The Journal of Biological Chemistry. 274: 22862-70. PMID 10428872 DOI: 10.1074/Jbc.274.32.22862  0.373
1999 Hockin MF, Cawthern KM, Kalafatis M, Mann KG. A model describing the inactivation of factor Va by APC: bond cleavage, fragment dissociation, and product inhibition. Biochemistry. 38: 6918-34. PMID 10346914 DOI: 10.1021/Bi981966E  0.388
1999 Kalafatis M, Bernardi F, Simioni P, Lunghi B, Girolami A, Mann KG. Phenotype and genotype expression in pseudohomozygous factor VLEIDEN : the need for phenotype analysis. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 336-42. PMID 9974416 DOI: 10.1161/01.Atv.19.2.336  0.391
1999 Smiles AM, Macy EM, Sakkinen PA, Bovill EG, Mann KG, Tracy RP. Variability in plasma prothrombin concentration: implications for use in epidemiology. Blood Coagulation & Fibrinolysis : An International Journal in Haemostasis and Thrombosis. 9: 525-31. PMID 9819003 DOI: 10.1097/00001721-199809000-00010  0.336
1999 Butenas S, van’t Veer C, Mann KG. “Normal” Thrombin Generation Blood. 94: 2169-2178. DOI: 10.1182/Blood.V94.7.2169.419K22_2169_2178  0.44
1999 Butenas S, Golden N, Mann K, van't Veer C. Regulation of Prothrombinase Activity by Protein S Thrombosis and Haemostasis. 82: 80-87. DOI: 10.1055/S-0037-1614633  0.404
1998 Moyer MP, Tracy RP, Tracy PB, van't Veer C, Sparks CE, Mann KG. Plasma lipoproteins support prothrombinase and other procoagulant enzymatic complexes. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 458-65. PMID 9514415 DOI: 10.1161/01.Atv.18.3.458  0.306
1998 Hockin MF, Kalafatis M, Shatos M, Mann KG. Protein C activation and factor Va inactivation on human umbilical vein endothelial cells. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2765-75. PMID 9409254 DOI: 10.1161/01.Atv.17.11.2765  0.389
1998 Kalafatis M, Egan JO, van 't Veer C, Cawthern KM, Mann KG. The regulation of clotting factors. Critical Reviews in Eukaryotic Gene Expression. 7: 241-80. PMID 9399073 DOI: 10.1615/Critreveukargeneexpr.V7.I3.40  0.446
1998 Egan JO, Kalafatis M, Mann KG. The effect of Arg306-->Ala and Arg506-->Gln substitutions in the inactivation of recombinant human factor Va by activated protein C and protein S. Protein Science : a Publication of the Protein Society. 6: 2016-27. PMID 9300501 DOI: 10.1002/Pro.5560060922  0.413
1998 Cawthern KM, van ‘t Veer C, Lock JB, DiLorenzo ME, Branda RF, Mann KG. Blood Coagulation in Hemophilia A and Hemophilia C Blood. 91: 4581-4592. DOI: 10.1182/Blood.V91.12.4581.412K12_4581_4592  0.426
1997 Schneider DJ, Tracy PB, Mann KG, Sobel BE. Differential effects of anticoagulants on the activation of platelets ex vivo. Circulation. 96: 2877-83. PMID 9386152 DOI: 10.1161/01.Cir.96.9.2877  0.328
1997 Van 'T Veer C, Golden NJ, Kalafatis M, Simioni P, Bertina RM, Mann KG. An in vitro analysis of the combination of hemophilia A and factor V(LEIDEN) Blood. 90: 3067-3072. PMID 9376587 DOI: 10.1182/Blood.V90.8.3067  0.413
1997 Butenas S, van 't Veer C, Mann KG. Evaluation of the initiation phase of blood coagulation using ultrasensitive assays for serine proteases. The Journal of Biological Chemistry. 272: 21527-33. PMID 9261172 DOI: 10.1074/Jbc.272.34.21527  0.43
1997 Van 't Veer C, Kalafatis M, Bertina RM, Simioni P, Mann KG. Increased tissue factor-initiated prothrombin activation as a result of the Arg506 → Gln mutation in factor V(LEIDEN) Journal of Biological Chemistry. 272: 20721-20729. PMID 9252393 DOI: 10.1074/Jbc.272.33.20721  0.416
1997 Mann KG, Hockin MF, Begin KJ, Kalafatis M. Activated protein C cleavage of factor Va leads to dissociation of the A2 domain. The Journal of Biological Chemistry. 272: 20678-83. PMID 9252387 DOI: 10.1074/Jbc.272.33.20678  0.349
1997 Kalafatis M, Mann KG. Factor VLeiden and thrombophilia. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 620-7. PMID 9108773 DOI: 10.1161/01.Atv.17.4.620  0.456
1997 van 't Veer C, Golden NJ, Kalafatis M, Mann KG. Inhibitory mechanism of the protein C pathway on tissue factor-induced thrombin generation. Synergistic effect in combination with tissue factor pathway inhibitor. The Journal of Biological Chemistry. 272: 7983-94. PMID 9065469 DOI: 10.1074/Jbc.272.12.7983  0.414
1997 Butenas S, Kalafatis M, Mann KG. Analysis of tissue plasminogen activator specificity using peptidyl fluorogenic substrates. Biochemistry. 36: 2123-31. PMID 9047311 DOI: 10.1021/Bi9617670  0.312
1997 van 't Veer C, Mann KG. Regulation of tissue factor initiated thrombin generation by the stoichiometric inhibitors tissue factor pathway inhibitor, antithrombin-III, and heparin cofactor-II. The Journal of Biological Chemistry. 272: 4367-77. PMID 9020158 DOI: 10.1074/Jbc.272.7.4367  0.408
1997 Butenas S, DiLorenzo ME, Mann KG. Ultrasensitive Fluorogenic Substrates for Serine Proteases Thrombosis and Haemostasis. 78: 1193-1201. DOI: 10.1055/S-0038-1657714  0.386
1996 Rand MD, Lock JB, van't Veer C, Gaffney DP, Mann KG. Blood clotting in minimally altered whole blood. Blood. 88: 3432-45. PMID 8896408 DOI: 10.1182/Blood.V88.9.3432.Bloodjournal8893432  0.405
1996 Kalafatis M, Egan JO, van't Veer C, Mann KG. Regulation and regulatory role of gamma-carboxyglutamic acid containing clotting factors. Critical Reviews in Eukaryotic Gene Expression. 6: 87-101. PMID 8882309 DOI: 10.1615/Critreveukargeneexpr.V6.I1.60  0.396
1996 Cutsforth GA, Koppaka V, Krishnaswamy S, Wu JR, Mann KG, Lentz BR. Insights into the complex association of bovine factor Va with acidic-lipid-containing synthetic membranes. Biophysical Journal. 70: 2938-49. PMID 8744332 DOI: 10.1016/S0006-3495(96)79864-8  0.451
1996 Kalafatis M, Haley PE, Lu D, Bertina RM, Long GL, Mann KG. Proteolytic events that regulate factor V activity in whole plasma from normal and activated protein C (APC)-resistant individuals during clotting: an insight into the APC-resistance assay. Blood. 87: 4695-707. PMID 8639839 DOI: 10.1182/Blood.V87.11.4695.Bloodjournal87114695  0.399
1996 Butenas S, Mann KG. Kinetics of human factor VII activation. Biochemistry. 35: 1904-10. PMID 8639673 DOI: 10.1021/Bi951768C  0.418
1996 Janeway C, Rivard G, Tracy P, Mann K. Factor V Quebec revisited Blood. 87: 3571-3578. DOI: 10.1182/Blood.V87.9.3571.Bloodjournal8793571  0.397
1996 Lu D, Kalafatis M, Mann K, Long G. Comparison of activated protein C/protein S-mediated inactivation of human factor VIII and factor V Blood. 87: 4708-4717. DOI: 10.1182/Blood.V87.11.4708.Bloodjournal87114708  0.368
1995 Kalafatis M, Bertina RM, Rand MD, Mann KG. Characterization of the molecular defect in factor VR506Q. The Journal of Biological Chemistry. 270: 4053-7. PMID 7876154 DOI: 10.1074/Jbc.270.8.4053  0.416
1995 Bovill EG, Tracy RP, Hayes TE, Jenny RJ, Bhushan FH, Mann KG. Evidence that meizothrombin is an intermediate product in the clotting of whole blood Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 754-758. PMID 7773729 DOI: 10.1161/01.Atv.15.6.754  0.387
1995 Camire RM, Kalafatis M, Cushman M, Tracy RP, Mann KG, Tracy PB. The mechanism of inactivation of human platelet factor Va from normal and activated protein C-resistant individuals. The Journal of Biological Chemistry. 270: 20794-800. PMID 7657663 DOI: 10.1074/Jbc.270.35.20794  0.445
1995 Kalafatis M, Lu D, Bertina RM, Long GL, Mann KG. Biochemical prototype for familial thrombosis. A study combining a functional protein C mutation and factor V Leiden. Arteriosclerosis, Thrombosis, and Vascular Biology. 15: 2181-7. PMID 7489240 DOI: 10.1161/01.Atv.15.12.2181  0.365
1995 Rand M, Hanson S, Mann K. Factor V turnover in a primate model Blood. 86: 2616-2623. DOI: 10.1182/Blood.V86.7.2616.Bloodjournal8672616  0.387
1995 Murray J, Rand M, Egan J, Murphy S, Kim H, Mann K. Factor VNew Brunswick: Ala221-to-Val substitution results in reduced cofactor activity Blood. 86: 1820-1827. DOI: 10.1182/Blood.V86.5.1820.Bloodjournal8651820  0.341
1994 Kalafatis M, Xue J, Lawler CM, Mann KG. Contribution of the heavy and light chains of factor Va to the interaction with factor Xa Biochemistry®. 6538-6545. PMID 8204589 DOI: 10.1021/Bi00187A022  0.383
1994 Butenas S, Lawson JH, Kalafatis M, Mann KG. Cooperative interaction of divalent metal ions, substrate, and tissue factor with factor VIIa. Biochemistry. 33: 3449-56. PMID 8136382 DOI: 10.1021/Bi00177A039  0.407
1994 Stoylova S, Mann KG, Brisson A. Structure of membrane-bound human factor Va. Febs Letters. 351: 330-4. PMID 8082790 DOI: 10.1016/0014-5793(94)00881-7  0.362
1994 Vijayalakshmi J, Padmanabhan KP, Mann KG, Tulinsky A. The isomorphous structures of prethrombin2, hirugen-, and PPACK-thrombin: changes accompanying activation and exosite binding to thrombin. Protein Science : a Publication of the Protein Society. 3: 2254-71. PMID 7756983 DOI: 10.1002/Pro.5560031211  0.324
1994 Lu D, Kalafatis M, Mann K, Long G. Loss of membrane-dependent factor Va cleavage: a mechanistic interpretation of the pathology of protein CVermont Blood. 84: 687-690. DOI: 10.1182/Blood.V84.3.687.687  0.358
1994 Rand M, Kalafatis M, Mann K. Platelet coagulation factor Va: the major secretory platelet phosphoprotein Blood. 83: 2180-2190. DOI: 10.1182/Blood.V83.8.2180.Bloodjournal8382180  0.388
1993 Krishnaswamy S, Nesheim ME, Pryzdial EL, Mann KG. Assembly of prothrombinase complex. Methods in Enzymology. 222: 260-80. PMID 8412798 DOI: 10.1016/0076-6879(93)22018-B  0.488
1993 Kalafatis M, Krishnaswamy S, Rand MD, Mann KG. Factor V. Methods in Enzymology. 222: 224-36. PMID 8412796 DOI: 10.1016/0076-6879(93)22016-9  0.578
1993 Lawson JH, Krishnaswamy S, Butenas S, Mann KG. Extrinsic pathway proteolytic activity. Methods in Enzymology. 222: 177-95. PMID 8412793 DOI: 10.1016/0076-6879(93)22013-6  0.582
1993 Butenas S, Ribarik N, Mann KG. Synthetic substrates for human factor VIIa and factor VIIa-tissue factor. Biochemistry. 32: 6531-8. PMID 8329383 DOI: 10.1021/Bi00077A006  0.32
1993 Swords NA, Tracy PB, Mann KG. Intact platelet membranes, not platelet-released microvesicles, support the procoagulant activity of adherent platelets. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 13: 1613-22. PMID 8218102 DOI: 10.1161/01.Atv.13.11.1613  0.32
1993 Swords NA, Mann KG. The assembly of the prothrombinase complex on adherent platelets. Arteriosclerosis and Thrombosis : a Journal of Vascular Biology. 13: 1602-12. PMID 8218101 DOI: 10.1161/01.Atv.13.11.1602  0.366
1993 Kalafatis M, Rand M, Jenny R, Ehrlich Y, Mann K. Phosphorylation of factor Va and factor VIIIa by activated platelets Blood. 81: 704-719. DOI: 10.1182/Blood.V81.3.704.704  0.344
1992 Mann KG, Krishnaswamy S, Lawson JH. Surface-dependent hemostasis. Seminars in Hematology. 29: 213-26. PMID 1641667  0.381
1992 Butenas S, Orfeo T, Lawson JH, Mann KG. Aminonaphthalenesulfonamides, a new class of modifiable fluorescent detecting groups and their use in substrates for serine protease enzymes. Biochemistry. 31: 5399-411. PMID 1606166 DOI: 10.1021/Bi00138A023  0.352
1992 Kelm RJ, Hair GA, Mann KG, Grant BW. Characterization of human osteoblast and megakaryocyte-derived osteonectin (SPARC) Blood. 80: 3112-3119. PMID 1467517 DOI: 10.1182/Blood.V80.12.3112.Bloodjournal80123112  0.313
1992 Krishnaswamy S, Field KA, Edgington TS, Morrissey JH, Mann KG. Role of the membrane surface in the activation of human coagulation factor X. The Journal of Biological Chemistry. 267: 26110-20. PMID 1464622  0.516
1992 Nesheim ME, Tracy RP, Tracy PB, Boskovic DS, Mann KG. Mathematical simulation of prothrombinase Methods in Enzymology. 215: 316-328. PMID 1435332 DOI: 10.1016/0076-6879(92)15074-M  0.715
1992 Mann KG. Potential analyzes for the diagnosis of thrombosis An overview Annals of Epidemiology. 2: 365-370. PMID 1342287 DOI: 10.1016/1047-2797(92)90085-5  0.389
1992 Tracy PB, Nesheim ME, Mann KG. Platelet factor Xa receptor. Methods in Enzymology. 215: 329-60. PMID 1331708 DOI: 10.1016/0076-6879(92)15075-N  0.395
1991 Mann KG, Bovill EG, Krishnaswamy S. Surface-dependent reactions in the propagation phase of blood coagulation. Annals of the New York Academy of Sciences. 614: 63-75. PMID 2024894 DOI: 10.1111/J.1749-6632.1991.Tb43692.X  0.492
1991 Bovill EG, Landesman MM, Busch SA, Fregeau GR, Mann KG, Tracy RP. Studies on the measurement of protein S in plasma Clinical Chemistry. 37: 1708-1714. DOI: 10.1093/Clinchem/37.10.1708  0.31
1990 Jenny RJ, Mann KG. Factor V: a prototype pro-cofactor for vitamin K-dependent enzyme complexes in blood clotting. Bailliere's Clinical Haematology. 2: 919-44. PMID 2513010 DOI: 10.1016/S0950-3536(89)80052-6  0.394
1990 Tracy RP, Andrianorivo A, Riggs BL, Mann KG. Comparison of monoclonal and polyclonal antibody-based immunoassays for osteocalcin: a study of sources of variation in assay results. Journal of Bone and Mineral Research : the Official Journal of the American Society For Bone and Mineral Research. 5: 451-61. PMID 2368627 DOI: 10.1002/Jbmr.5650050506  0.318
1990 Mosesson MW, Church WR, DiOrio JP, Krishnaswamy S, Mann KG, Hainfeld JF, Wall JS. Structural model of factors V and Va based on scanning transmission electron microscope images and mass analysis. The Journal of Biological Chemistry. 265: 8863-8. PMID 2341407  0.439
1990 Kelm RJ, Mann KG. Human platelet osteonectin: Release, surface expression, and partial characterization Blood. 75: 1105-1113. PMID 2306517 DOI: 10.1182/Blood.V75.5.1105.1105  0.334
1990 Mann KG, Nesheim ME, Church WR, Haley P, Krishnaswamy S. Surface-dependent reactions of the vitamin K-dependent enzyme complexes. Blood. 76: 1-16. PMID 2194585 DOI: 10.1182/Blood.V76.1.1.1  0.599
1990 Mann KG, Williams EB, Krishnaswamy S, Church W, Giles A, Tracy RP. Active site-specific immunoassays. Blood. 76: 755-66. PMID 2116928 DOI: 10.1182/Blood.V76.4.755.Bloodjournal764755  0.558
1990 Lawson J, Pennell B, Olson J, Mann K. Isolation and characterization of an acquired antithrombin antibody Blood. 76: 2249-2257. DOI: 10.1182/Blood.V76.11.2249.Bloodjournal76112249  0.312
1990 Mann K, Nesheim M, Church W, Haley P, Krishnaswamy S. Surface-dependent reactions of the vitamin K-dependent enzyme complexes Blood. 76: 1-16. DOI: 10.1182/blood.v76.1.1.bloodjournal7611  0.319
1989 Henriksen RA, Mann KG. Identification of the primary structural defect in the dysthrombin thrombin Quick I: substitution of cysteine for arginine-382. Biochemistry. 27: 9160-5. PMID 3242619 DOI: 10.1021/Bi00426A013  0.354
1989 Krishnaswamy S, Russell GD, Mann KG. The reassociation of factor Va from its isolated subunits. The Journal of Biological Chemistry. 264: 3160-8. PMID 2914947  0.492
1989 Gendreau MA, Krishnaswamy S, Mann KG. The interaction of bone Gla protein (osteocalcin) with phospholipid vesicles. The Journal of Biological Chemistry. 264: 6972-8. PMID 2785110  0.487
1989 Williams EB, Krishnaswamy S, Mann KG. Zymogen/enzyme discrimination using peptide chloromethyl ketones. The Journal of Biological Chemistry. 264: 7536-45. PMID 2708377  0.535
1989 Lee C, Mann K. Activation/inactivation of human factor V by plasmin Blood. 73: 185-190. DOI: 10.1182/Blood.V73.1.185.Bloodjournal731185  0.412
1988 Yamasaki K, Jamal N, Mann KG, Messner HA. Megakaryocyte colony growth-supporting activities in human plasma: modification by platelets and platelet membranes. Journal of Cellular Physiology. 133: 337-43. PMID 3500177 DOI: 10.1002/Jcp.1041330218  0.343
1988 Krishnaswamy S, Jones KC, Mann KG. Prothrombinase complex assembly. Kinetic mechanism of enzyme assembly on phospholipid vesicles. The Journal of Biological Chemistry. 263: 3823-34. PMID 3346225  0.469
1988 Krishnaswamy S, Mann KG. The binding of factor Va to phospholipid vesicles. The Journal of Biological Chemistry. 263: 5714-23. PMID 3162734  0.499
1988 Stump DC, Mann KG. Mechanisms of thrombus formation and lysis. Annals of Emergency Medicine. 17: 1138-47. PMID 3142314 DOI: 10.1016/S0196-0644(88)80059-3  0.372
1988 Mann KG, Jenny RJ, Krishnaswamy S. Cofactor proteins in the assembly and expression of blood clotting enzyme complexes. Annual Review of Biochemistry. 57: 915-56. PMID 3052293 DOI: 10.1146/Annurev.Bi.57.070188.004411  0.516
1988 Church W, Messier T, Tucker M, Mann K. An inhibitory monoclonal antibody to factor X that blocks prothrombin activation but not prothrombinase enzyme assembly Blood. 72: 1911-1921. DOI: 10.1182/Blood.V72.6.1911.1911  0.377
1988 Howard PR, Bovill EG, Mann KG, Tracy RP. A monoclonal-antibody-based radioimmunoassay for measurement of protein C in plasma. Clinical Chemistry. 34: 324-330. DOI: 10.1093/Clinchem/34.2.320  0.304
1987 Krishnaswamy S, Church WR, Nesheim ME, Mann KG. Activation of human prothrombin by human prothrombinase. Influence of factor Va on the reaction mechanism. The Journal of Biological Chemistry. 262: 3291-9. PMID 3818642  0.491
1987 Lecompte MF, Krishnaswamy S, Mann KG, Nesheim ME, Gitler C. Membrane penetration of bovine factor V and Va detected by labeling with 5-iodonaphthalene-1-azide. The Journal of Biological Chemistry. 262: 1935-7. PMID 3818583  0.494
1987 Bar-Shavit R, Kahn AJ, Mann KG, Wilner GD. Growth-promoting effects of esterolytically inactive thrombin on macrophages. Journal of Cellular Biochemistry. 32: 261-72. PMID 3805133 DOI: 10.1002/Jcb.240320403  0.316
1987 Tracy PB, Mann KG. Abnormal formation of the prothrombinase complex: factor V deficiency and related disorders. Human Pathology. 18: 162-9. PMID 3804320 DOI: 10.1016/S0046-8177(87)80334-9  0.435
1987 Grant B, Nichols W, Solberg L, Yachimiak D, Mann K. Quantitation of human in vitro megakaryocytopoiesis by radioimmunoassay Blood. 69: 1334-1339. DOI: 10.1182/Blood.V69.5.1334.Bloodjournal6951334  0.321
1987 Mann KG. The assembly of blood clotting complexes on membranes Trends in Biochemical Sciences. 12: 229-233. DOI: 10.1016/0968-0004(87)90115-0  0.301
1986 Krishnaswamy S, Williams EB, Mann KG. The binding of activated protein C to factors V and Va. The Journal of Biological Chemistry. 261: 9684-93. PMID 3755431  0.521
1986 Krishnaswamy S, Mann KG, Nesheim ME. The prothrombinase-catalyzed activation of prothrombin proceeds through the intermediate meizothrombin in an ordered, sequential reaction. The Journal of Biological Chemistry. 261: 8977-84. PMID 3755135  0.485
1986 Bar-Shavit R, Kahn AJ, Mann KG, Wilner GD. Identification of a thrombin sequence with growth factor activity on macrophages. Proceedings of the National Academy of Sciences of the United States of America. 83: 976-80. PMID 3456576 DOI: 10.1073/Pnas.83.4.976  0.35
1986 Mann KG, Nesheim ME, Tracy PB. Chapter 2A Nonenzymatic cofactors: factor V* New Comprehensive Biochemistry. 13: 15-34. DOI: 10.1016/S0167-7306(08)60046-0  0.401
1985 Church WR, Jernigan RL, Toole J, Hewick RM, Knopf J, Knutson GJ, Nesheim ME, Mann KG, Fass DN. Coagulation factors V and VIII and ceruloplasmin constitute a family of structurally related proteins. Proceedings of the National Academy of Sciences of the United States of America. 81: 6934-7. PMID 6438625 DOI: 10.1073/Pnas.81.22.6934  0.353
1985 Fass DN, Hewick RM, Knutson GJ, Nesheim ME, Mann KG. Internal duplication and sequence homology in factors V and VIII Proceedings of the National Academy of Sciences of the United States of America. 82: 1688-1691. PMID 3920653 DOI: 10.1073/Pnas.82.6.1688  0.418
1985 Nichols W, Gastineau D, Solberg L, Mann K. Identification of human megakaryocyte coagulation factor V Blood. 65: 1396-1406. DOI: 10.1182/Blood.V65.6.1396.1396  0.368
1984 Bar-Shavit R, Kahn A, Mudd MS, Wilner GD, Mann KG, Fenton JW. Localization of a chemotactic domain in human thrombin. Biochemistry. 23: 397-400. PMID 6704377 DOI: 10.1021/Bi00298A001  0.309
1984 Tracy PB, Giles AR, Mann KG, Eide LL, Hoogendoorn H, Rivard GE. Factor V (Quebec): a bleeding diathesis associated with a qualitative platelet Factor V deficiency. The Journal of Clinical Investigation. 74: 1221-8. PMID 6480825 DOI: 10.1172/JCI111531  0.309
1983 Tucker MM, Nesheim ME, Mann KG. Differentiation of enzyme and substrate binding in the prothrombinase complex. Biochemistry. 22: 4540-6. PMID 6626514 DOI: 10.1021/Bi00288A029  0.349
1983 Foster W, Tucker M, Katzmann J, Miller R, Nesheim M, Mann K. Monoclonal antibodies to human coagulation factor V and factor Va Blood. 61: 1060-1067. DOI: 10.1182/Blood.V61.6.1060.1060  0.387
1982 Nesheim ME, Katzmann JA, Tracy PB, Mann KG. Factor V. Methods in Enzymology. 249-74. PMID 7043191 DOI: 10.1016/S0076-6879(81)80023-7  0.39
1982 Hibbard LS, Nesheim ME, Mann KG. Progressive development of a thrombin inhibitor binding site. Biochemistry. 21: 2285-92. PMID 6896460 DOI: 10.1021/Bi00539A003  0.32
1982 Tracy P, Eide L, Bowie E, Mann K. Radioimmunoassay of factor V in human plasma and platelets Blood. 60: 59-63. DOI: 10.1182/Blood.V60.1.59.Bloodjournal60159  0.397
1982 Giles A, Nesheim M, Hoogendoorn H, Tracy P, Mann K. The coagulant-active phospholipid content is a major determinant of in vivo thrombogenicity of prothrombin complex (Factor IX) concentrates in rabbits Blood. 59: 401-407. DOI: 10.1182/Blood.V59.2.401.Bloodjournal592401  0.386
1981 Mann KG, Nesheim ME, Tracy PB. Molecular weight of undegraded plasma factor V. Biochemistry. 20: 28-33. PMID 7470475 DOI: 10.1021/Bi00504A005  0.379
1981 Katzmann JA, Nesheim ME, Hibbard LS, Mann KG. Isolation of functional human coagulation factor V by using a hybridoma antibody. Proceedings of the National Academy of Sciences of the United States of America. 78: 162-6. PMID 6941242 DOI: 10.1073/Pnas.78.1.162  0.374
1979 Tuhy PM, Bloom JW, Mann KG. Decarboxylation of bovine prothrombin fragment 1 and prothrombin. Biochemistry. 18: 5842-8. PMID 518871 DOI: 10.1021/Bi00593A014  0.309
1979 Bloom JW, Nesheim ME, Mann KG. Phospholipid-binding properties of bovine factor V and factor Va. Biochemistry. 18: 4419-25. PMID 486430 DOI: 10.1021/Bi00587A023  0.366
1979 Downing MR, Elion J, Butkowski RJ, Mann KG. Thrombin: structural features related to specificity. Bibliotheca Haematologica. 44: 39-53. PMID 367359 DOI: 10.1159/000402149  0.304
1972 Huston JS, Fish WW, Mann KG, Tanford C. Studies on the subunit molecular weight of beef heart lactate dehydrogenase. Biochemistry. 11: 1609-12. PMID 5063709 DOI: 10.1021/Bi00759A010  0.478
1970 Mann KG, Vestling CS. Isozymes of rat liver mitochondrial malate dehydrogenase. Evidence for the existence of nonidentical subunits. Biochemistry. 9: 3020-5. PMID 5474803 DOI: 10.1021/Bi00817A013  0.637
1970 Mann KG, Fish WW, Cox AC, Tanford C. Single-chain nature of human serum transferrin. Biochemistry. 9: 1348-54. PMID 5418370  0.437
1969 Fish WW, Mann KG, Tanford C. The estimation of polypeptide chain molecular weights by gel filtration in 6 M guanidine hydrochloride. The Journal of Biological Chemistry. 244: 4989-94. PMID 5824574  0.427
1969 Mann KG, Vestling CS. Subunits of rat liver mitochondrial malate dehydrogenase. Biochemistry. 8: 1105-9. PMID 5781004 DOI: 10.1021/Bi00831A042  0.635
1968 Mann KG, Vestling CS. Nature of the isozymes of rat liver mitochondrial malate dehydrogenase. Biochimica Et Biophysica Acta. 159: 567-9. PMID 5657877 DOI: 10.1016/0005-2744(68)90148-4  0.608
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