Cesar de la Fuente-Nunez, Ph.D. - Publications

Affiliations: 
Bioengineering, Microbiology, Psychiatry University of Pennsylvania, Philadelphia, PA, United States 
Area:
Peptide design and engineering, synthetic biology, microbiology, computational biology
Website:
https://delafuentelab.seas.upenn.edu/

88 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Boaro A, Ageitos L, Torres MT, Blasco EB, Oztekin S, de la Fuente-Nunez C. Structure-function-guided design of synthetic peptides with anti-infective activity derived from wasp venom. Cell Reports. Physical Science. 4. PMID 38239869 DOI: 10.1016/j.xcrp.2023.101459  0.461
2023 Nazarian-Firouzabadi F, Torres MT, de la Fuente-Nunez C. Recombinant production of antimicrobial peptides in plants. Biotechnology Advances. 108296. PMID 38042311 DOI: 10.1016/j.biotechadv.2023.108296  0.337
2023 de la Fuente-Nunez C, Cesaro A, Hancock REW. Antibiotic failure: Beyond antimicrobial resistance. Drug Resistance Updates : Reviews and Commentaries in Antimicrobial and Anticancer Chemotherapy. 71: 101012. PMID 37924726 DOI: 10.1016/j.drup.2023.101012  0.344
2023 Chiloeches A, Zágora J, Plachá D, Torres MDT, de la Fuente-Nunez C, López-Fabal F, Gil-Romero Y, Fernández-García R, Fernández-García M, Echeverría C, Muñoz-Bonilla A. Synergistic Combination of Antimicrobial Peptides and Cationic Polyitaconates in Multifunctional PLA Fibers. Acs Applied Bio Materials. PMID 37862451 DOI: 10.1021/acsabm.3c00576  0.306
2023 Pedron CN, Torres MT, Oliveira CS, Silva AF, Andrade GP, Wang Y, Pinhal MAS, Cerchiaro G, da Silva Junior PI, da Silva FD, Radhakrishnan R, de la Fuente-Nunez C, Oliveira Junior VX. Molecular hybridization strategy for tuning bioactive peptide function. Communications Biology. 6: 1067. PMID 37857855 DOI: 10.1038/s42003-023-05254-7  0.41
2023 Torres MDT, Brooks E, Cesaro A, Sberro H, Nicolaou C, Bhatt AS, de la Fuente-Nunez C. Human gut metagenomic mining reveals an untapped source of peptide antibiotics. Biorxiv : the Preprint Server For Biology. PMID 37693399 DOI: 10.1101/2023.08.31.555711  0.486
2023 Aguilera-Puga MDC, Cancelarich NL, Marani MM, de la Fuente-Nunez C, Plisson F. Accelerating the Discovery and Design of Antimicrobial Peptides with Artificial Intelligence. Methods in Molecular Biology (Clifton, N.J.). 2714: 329-352. PMID 37676607 DOI: 10.1007/978-1-0716-3441-7_18  0.36
2023 Maasch JRMA, Torres MDT, Melo MCR, de la Fuente-Nunez C. Molecular de-extinction of ancient antimicrobial peptides enabled by machine learning. Cell Host & Microbe. 31: 1260-1274.e6. PMID 37516110 DOI: 10.1016/j.chom.2023.07.001  0.419
2023 Wong F, de la Fuente-Nunez C, Collins JJ. Leveraging artificial intelligence in the fight against infectious diseases. Science (New York, N.Y.). 381: 164-170. PMID 37440620 DOI: 10.1126/science.adh1114  0.461
2023 Wan F, de la Fuente-Nunez C. Mining for antimicrobial peptides in sequence space. Nature Biomedical Engineering. PMID 37095317 DOI: 10.1038/s41551-023-01027-z  0.3
2023 Cesaro A, Lin S, Pardi N, de la Fuente-Nunez C. Advanced delivery systems for peptide antibiotics. Advanced Drug Delivery Reviews. 196: 114733. PMID 36804008 DOI: 10.1016/j.addr.2023.114733  0.433
2022 Ageitos L, Torres MDT, de la Fuente-Nunez C. Biologically Active Peptides from Venoms: Applications in Antibiotic Resistance, Cancer, and Beyond. International Journal of Molecular Sciences. 23. PMID 36499761 DOI: 10.3390/ijms232315437  0.434
2022 Torres MDT, Melo MCR, Flowers L, Crescenzi O, Notomista E, de la Fuente-Nunez C. Author Correction: Mining for encrypted peptide antibiotics in the human proteome. Nature Biomedical Engineering. PMID 36456858 DOI: 10.1038/s41551-022-00967-2  0.358
2022 Li T, Wang Z, Guo J, de la Fuente-Nunez C, Wang J, Han B, Tao H, Liu J, Wang X. Bacterial resistance to antibacterial agents: Mechanisms, control strategies, and implications for global health. The Science of the Total Environment. 160461. PMID 36435256 DOI: 10.1016/j.scitotenv.2022.160461  0.376
2022 Cardoso MH, Chan LY, Cândido ES, Buccini DF, Rezende SB, Torres MDT, Oshiro KGN, Silva ÍC, Gonçalves S, Lu TK, Santos NC, de la Fuente-Nunez C, Craik DJ, Franco OL. An N-capping asparagine-lysine-proline (NKP) motif contributes to a hybrid flexible/stable multifunctional peptide scaffold. Chemical Science. 13: 9410-9424. PMID 36093022 DOI: 10.1039/d1sc06998e  0.61
2022 Hao Y, Wang J, de la Fuente-Nunez C, Franco OL. Editorial: Antimicrobial Peptides: Molecular Design, Structure-Function Relationship, and Biosynthesis Optimization. Frontiers in Microbiology. 13: 888540. PMID 35495692 DOI: 10.3389/fmicb.2022.888540  0.311
2022 Arqué X, Torres MDT, Patiño T, Boaro A, Sánchez S, de la Fuente-Nunez C. Autonomous Treatment of Bacterial Infections Using Antimicrobial Micro- and Nanomotors. Acs Nano. PMID 35486889 DOI: 10.1021/acsnano.1c11013  0.42
2022 Cesaro A, Torres MDT, Gaglione R, Dell'Olmo E, Di Girolamo R, Bosso A, Pizzo E, Haagsman HP, Veldhuizen EJA, de la Fuente-Nunez C, Arciello A. Synthetic Antibiotic Derived from Sequences Encrypted in a Protein from Human Plasma. Acs Nano. 16: 1880-1895. PMID 35112568 DOI: 10.1021/acsnano.1c04496  0.485
2021 Cesaro A, Torres MT, de la Fuente-Nunez C. Methods for the design and characterization of peptide antibiotics. Methods in Enzymology. 663: 303-326. PMID 35168794 DOI: 10.1016/bs.mie.2021.11.003  0.478
2021 Torres MDT, Melo MCR, Crescenzi O, Notomista E, de la Fuente-Nunez C. Mining for encrypted peptide antibiotics in the human proteome. Nature Biomedical Engineering. PMID 34737399 DOI: 10.1038/s41551-021-00801-1  0.502
2021 Ageitos L, de la Fuente-Nunez C. Antimicrobial Peptides: Potential Therapeutics Against Drug-Resistant Pulmonary Infections. Archivos De Bronconeumologia. PMID 34642532 DOI: 10.1016/j.arbres.2021.09.007  0.418
2021 Melo MCR, Maasch JRMA, de la Fuente-Nunez C. Accelerating antibiotic discovery through artificial intelligence. Communications Biology. 4: 1050. PMID 34504303 DOI: 10.1038/s42003-021-02586-0  0.408
2021 Oliveira CS, Torres MT, Pedron CN, Andrade VB, Silva PI, Silva FD, de la Fuente-Nunez C, Oliveira VX. Synthetic Peptide Derived from Scorpion Venom Displays Minimal Toxicity and Anti-infective Activity in an Animal Model. Acs Infectious Diseases. PMID 34463484 DOI: 10.1021/acsinfecdis.1c00261  0.46
2021 Mejía-Pitta A, Broset E, de la Fuente-Nunez C. Probiotic engineering strategies for heterologous production of antimicrobial peptides. Advanced Drug Delivery Reviews. 113863. PMID 34273423 DOI: 10.1016/j.addr.2021.113863  0.488
2021 Meurer M, O'Neil DA, Lovie E, Simpson L, Torres MDT, de la Fuente-Nunez C, Angeles-Boza AM, Kleinsorgen C, Mercer DK, von Köckritz-Blickwede M. Antimicrobial Susceptibility Testing of Antimicrobial Peptides Requires New and Standardized Testing Structures. Acs Infectious Diseases. PMID 34110786 DOI: 10.1021/acsinfecdis.1c00210  0.347
2021 Tang TC, Tham E, Liu X, Yehl K, Rovner AJ, Yuk H, de la Fuente-Nunez C, Isaacs FJ, Zhao X, Lu TK. Hydrogel-based biocontainment of bacteria for continuous sensing and computation. Nature Chemical Biology. PMID 33820990 DOI: 10.1038/s41589-021-00779-6  0.543
2021 Silveira GGOS, Torres MDT, Ribeiro CFA, Meneguetti BT, Carvalho CME, de la Fuente-Nunez C, Franco OL, Cardoso MH. Antibiofilm Peptides: Relevant Preclinical Animal Infection Models and Translational Potential. Acs Pharmacology & Translational Science. 4: 55-73. PMID 33615161 DOI: 10.1021/acsptsci.0c00191  0.417
2021 Palmer N, Maasch JRMA, Torres MDT, de la Fuente-Nunez C. Molecular dynamics for antimicrobial peptide discovery. Infection and Immunity. PMID 33558318 DOI: 10.1128/IAI.00703-20  0.42
2021 Torres MDT, Cao J, Franco OL, Lu TK, de la Fuente-Nunez C. Synthetic Biology and Computer-Based Frameworks for Antimicrobial Peptide Discovery. Acs Nano. PMID 33538585 DOI: 10.1021/acsnano.0c09509  0.657
2021 Pedron CN, Silva AF, Torres MT, Oliveira CS, Andrade GP, Cerchiaro G, Pinhal MAS, de la Fuente-Nunez C, Oliveira Junior VX. Net charge tuning modulates the antiplasmodial and anticancer properties of peptides derived from scorpion venom. Journal of Peptide Science : An Official Publication of the European Peptide Society. e3296. PMID 33442881 DOI: 10.1002/psc.3296  0.403
2021 Torres MDT, Voskian S, Brown P, Liu A, Lu TK, Hatton TA, de la Fuente-Nunez C. Coatable and Resistance-Proof Ionic Liquid for Pathogen Eradication. Acs Nano. PMID 33438392 DOI: 10.1021/acsnano.0c07642  0.551
2020 Boaro A, Ageitos L, Torres M, Bartoloni FH, de la Fuente-Nunez C. Light-Emitting Probes for Labeling Peptides. Cell Reports. Physical Science. 1. PMID 34396352 DOI: 10.1016/j.xcrp.2020.100257  0.333
2020 Ahmed A, Bakovic A, Risner K, Kortchak S, Der Torossian Torres M, de la Fuente-Nunez C, Lu T, Bhalla N, Narayanan A. Synthetic Host Defense Peptides Inhibit Venezuelan Equine Encephalitis Virus Replication and the Associated Inflammatory Response. Scientific Reports. 10: 21491. PMID 33293592 DOI: 10.1038/s41598-020-77990-3  0.612
2020 Kazemzadeh-Narbat M, Cheng H, Chabok R, Alvarez MM, de la Fuente-Nunez C, Phillips KS, Khademhosseini A. Strategies for antimicrobial peptide coatings on medical devices: a review and regulatory science perspective. Critical Reviews in Biotechnology. 1-27. PMID 33070659 DOI: 10.1080/07388551.2020.1828810  0.343
2020 Silva ON, Torres MDT, Cao J, Alves ESF, Rodrigues LV, Resende JM, Lião LM, Porto WF, Fensterseifer ICM, Lu TK, Franco OL, de la Fuente-Nunez C. Repurposing a peptide toxin from wasp venom into antiinfectives with dual antimicrobial and immunomodulatory properties. Proceedings of the National Academy of Sciences of the United States of America. PMID 33046640 DOI: 10.1073/pnas.2012379117  0.678
2020 Torres MDT, Silva AF, Andrade GP, Pedron CN, Cerchiaro G, Ribeiro AO, Oliveira VX, de la Fuente-Nunez C. The wasp venom antimicrobial peptide polybia-CP and its synthetic derivatives display antiplasmodial and anticancer properties. Bioengineering & Translational Medicine. 5: e10167. PMID 33005737 DOI: 10.1002/btm2.10167  0.411
2020 Mercer DK, Torres MDT, Duay SS, Lovie E, Simpson L, von Köckritz-Blickwede M, de la Fuente-Nunez C, O'Neil DA, Angeles-Boza AM. Antimicrobial Susceptibility Testing of Antimicrobial Peptides to Better Predict Efficacy. Frontiers in Cellular and Infection Microbiology. 10: 326. PMID 32733816 DOI: 10.3389/fcimb.2020.00326  0.43
2020 Magana M, Pushpanathan M, Santos AL, Leanse L, Fernandez M, Ioannidis A, Giulianotti MA, Apidianakis Y, Bradfute S, Ferguson AL, Cherkasov A, Seleem MN, Pinilla C, de la Fuente-Nunez C, Lazaridis T, et al. The value of antimicrobial peptides in the age of resistance. The Lancet. Infectious Diseases. PMID 32653070 DOI: 10.1016/S1473-3099(20)30327-3  0.502
2020 Gaglione R, Pizzo E, Notomista E, de la Fuente-Nunez C, Arciello A. Host defence cryptides from human apolipoproteins: applications in medicinal chemistry. Current Topics in Medicinal Chemistry. PMID 32338222 DOI: 10.2174/1568026620666200427091454  0.408
2019 Der Torossian Torres M, de la Fuente-Nunez C. Reprogramming biological peptides to combat infectious diseases. Chemical Communications (Cambridge, England). 55: 15020-15032. PMID 31782426 DOI: 10.1039/C9Cc07898C  0.51
2019 Inda ME, Broset E, Lu TK, de la Fuente-Nunez C. Emerging Frontiers in Microbiome Engineering. Trends in Immunology. PMID 31601521 DOI: 10.1016/J.It.2019.08.007  0.502
2019 Yehl K, Lemire S, Yang AC, Ando H, Mimee M, Torres MT, de la Fuente-Nunez C, Lu TK. Engineering Phage Host-Range and Suppressing Bacterial Resistance through Phage Tail Fiber Mutagenesis. Cell. 179: 459-469.e9. PMID 31585083 DOI: 10.1016/J.Cell.2019.09.015  0.711
2019 Agbale CM, Sarfo JK, Galyuon IK, Juliano SA, Silva GGO, Buccini DF, Cardoso MH, Torres MDT, Angeles-Boza AM, de la Fuente-Nunez C, Franco OL. Antimicrobial and Antibiofilm Activities of Helical Antimicrobial Peptide Sequences Incorporating Metal-Binding Motifs. Biochemistry. PMID 31448597 DOI: 10.1021/Acs.Biochem.9B00440  0.42
2019 Oshiro KGN, Cândido ES, Chan LY, Torres MT, Monges BED, Rodrigues SG, Porto WF, Ribeiro SM, Troeira Henriques S, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL, Cardoso MH. Computer-aided design of mastoparan-like peptides enables the generation of non-toxic variants with extended antibacterial properties. Journal of Medicinal Chemistry. PMID 31411881 DOI: 10.1021/Acs.Jmedchem.9B00915  0.559
2019 de la Fuente-Nunez C. Toward Autonomous Antibiotic Discovery. Msystems. 4. PMID 31186311 DOI: 10.1128/mSystems.00151-19  0.348
2019 Torres MT, de la Fuente-Nunez C. Toward computer-made artificial antibiotics. Current Opinion in Microbiology. 51: 30-38. PMID 31082661 DOI: 10.1016/J.Mib.2019.03.004  0.446
2019 Cândido ES, Cardoso MH, Chan LY, Torres MT, Oshiro K, Porto WF, Ribeiro SM, Haney EF, Hancock REW, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL. A short cationic peptide derived from Archaea with dual antibacterial properties and anti-infective potential. Acs Infectious Diseases. PMID 31016969 DOI: 10.1021/Acsinfecdis.9B00073  0.657
2019 Fensterseifer ICM, Felício MR, Alves ESF, Cardoso MH, Torres MDT, Matos CO, Silva ON, Lu TK, Freire MV, Neves NC, Gonçalves S, Lião LM, Santos NC, Porto WF, de la Fuente-Nunez C, et al. Selective antibacterial activity of the cationic peptide PaDBS1R6 against Gram-negative bacteria. Biochimica Et Biophysica Acta. Biomembranes. PMID 30926365 DOI: 10.1016/J.Bbamem.2019.03.016  0.664
2019 Ahmed A, Siman-Tov G, Keck F, Kortchak S, Bakovic A, Risner K, Lu TK, Bhalla N, de la Fuente-Nunez C, Narayanan A. Human cathelicidin peptide LL-37 as a therapeutic antiviral targeting Venezuelan equine encephalitis virus infections. Antiviral Research. PMID 30738837 DOI: 10.1016/J.Antiviral.2019.02.002  0.568
2019 Torres MDT, Sothiselvam S, Lu TK, de la Fuente-Nunez C. Peptide Design Principles for Antimicrobial Applications. Journal of Molecular Biology. PMID 30611750 DOI: 10.1016/J.Jmb.2018.12.015  0.666
2018 Fleitas Martínez O, Rigueiras PO, Pires ÁDS, Porto WF, Silva ON, de la Fuente-Nunez C, Franco OL. Interference With Quorum-Sensing Signal Biosynthesis as a Promising Therapeutic Strategy Against Multidrug-Resistant Pathogens. Frontiers in Cellular and Infection Microbiology. 8: 444. PMID 30805311 DOI: 10.3389/fcimb.2018.00444  0.353
2018 Torres MDT, Pedron CN, Higashikuni Y, Kramer RM, Cardoso MH, Oshiro KGN, Franco OL, Silva Junior PI, Silva FD, Oliveira Junior VX, Lu TK, de la Fuente-Nunez C. Structure-function-guided exploration of the antimicrobial peptide polybia-CP identifies activity determinants and generates synthetic therapeutic candidates. Communications Biology. 1: 221. PMID 30534613 DOI: 10.1038/s42003-018-0224-2  0.672
2018 Cardoso M, Cândido E, Chan L, Torres MT, Oshiro K, Rezende S, Porto WF, Lu TK, de la Fuente-Nunez C, Craik DJ, Franco OL. A computationally designed peptide derived from Escherichia colias a potential drug template for antibacterial and antibiofilm therapies. Acs Infectious Diseases. PMID 30346140 DOI: 10.1021/Acsinfecdis.8B00219  0.654
2018 Pane K, Cafaro V, Avitabile A, Torres MT, Vollaro A, De Gregorio E, Catania MR, Di Maro A, Bosso A, Gallo G, Zanfardino A, Varcamonti M, Pizzo E, Di Donato A, Lu TK, ... de la Fuente-Nunez C, et al. Identification of Novel Cryptic Multifunctional Antimicrobial Peptides from the Human Stomach Enabled by a Computational-Experimental Platform. Acs Synthetic Biology. PMID 30124040 DOI: 10.1021/Acssynbio.8B00084  0.654
2018 Torres MDT, Andrade GP, Sato RH, Pedron CN, Manieri TM, Cerchiaro G, Ribeiro AO, de la Fuente-Nunez C, Oliveira VX. Natural and redesigned wasp venom peptides with selective antitumoral activity. Beilstein Journal of Organic Chemistry. 14: 1693-1703. PMID 30013694 DOI: 10.3762/Bjoc.14.144  0.341
2018 Pizzo E, Pane K, Bosso A, Landi N, Ragucci S, Russo R, Gaglione R, Torres MDT, de la Fuente-Nunez C, Arciello A, Di Donato A, Notomista E, Di Maro A. Novel bioactive peptides from PD-L1/2, a type 1 ribosome inactivating protein from Phytolacca dioica L. Evaluation of their antimicrobial properties and anti-biofilm activities. Biochimica Et Biophysica Acta. PMID 29684330 DOI: 10.1016/J.Bbamem.2018.04.010  0.376
2018 Porto WF, Irazazabal L, Alves ESF, Ribeiro SM, Matos CO, Pires ÁS, Fensterseifer ICM, Miranda VJ, Haney EF, Humblot V, Torres MDT, Hancock REW, Liao LM, Ladram A, Lu TK, ... de la Fuente-Nunez C, et al. In silico optimization of a guava antimicrobial peptide enables combinatorial exploration for peptide design. Nature Communications. 9: 1490. PMID 29662055 DOI: 10.1038/S41467-018-03746-3  0.627
2018 Cao J, de la Fuente-Nunez C, Ou RW, Torres MD, Pande SG, Sinskey AJ, Lu TK. Yeast-based synthetic biology platform for antimicrobial peptide production. Acs Synthetic Biology. PMID 29366323 DOI: 10.1021/Acssynbio.7B00396  0.651
2018 Cao J, Perez-Pinera P, Lowenhaupt K, Wu MR, Purcell O, de la Fuente-Nunez C, Lu TK. Versatile and on-demand biologics co-production in yeast. Nature Communications. 9: 77. PMID 29311542 DOI: 10.1038/S41467-017-02587-W  0.489
2017 de la Fuente-Nunez C, Meneguetti BT, Franco OL, Lu TK. Neuromicrobiology: How Microbes Influence the Brain. Acs Chemical Neuroscience. PMID 29220570 DOI: 10.1021/Acschemneuro.7B00373  0.474
2017 Liu X, Yuk H, Lin S, Parada GA, Tang TC, Tham E, de la Fuente-Nunez C, Lu TK, Zhao X. 3D Printing of Living Responsive Materials and Devices. Advanced Materials (Deerfield Beach, Fla.). PMID 29205532 DOI: 10.1002/Adma.201704821  0.441
2017 Silva AF, Torres MT, Silva LS, Alves FL, de Sá Pinheiro AA, Miranda A, Capurro ML, de la Fuente-Nunez C, Oliveira VX. Angiotensin II-derived constrained peptides with antiplasmodial activity and suppressed vasoconstriction. Scientific Reports. 7: 14326. PMID 29085013 DOI: 10.1038/S41598-017-14642-Z  0.339
2017 Verderosa AD, de la Fuente-Núñez C, Mansour SC, Cao J, Lu TK, Hancock REW, Fairfull-Smith KE. Ciprofloxacin-nitroxide hybrids with potential for biofilm control. European Journal of Medicinal Chemistry. 138: 590-601. PMID 28709125 DOI: 10.1016/J.Ejmech.2017.06.058  0.565
2017 de la Fuente-Nunez C, Torres MD, Mojica FJ, Lu TK. Next-generation precision antimicrobials: towards personalized treatment of infectious diseases. Current Opinion in Microbiology. 37: 95-102. PMID 28623720 DOI: 10.1016/J.Mib.2017.05.014  0.639
2017 de la Fuente-Núñez C, Silva ON, Lu TK, Franco OL. Antimicrobial Peptides: Role in Human Disease and Potential as Immunotherapies. Pharmacology & Therapeutics. PMID 28435091 DOI: 10.1016/J.Pharmthera.2017.04.002  0.618
2017 de la Fuente-Núñez C, Lu TK. CRISPR-Cas9 technology: applications in genome engineering, development of sequence-specific antimicrobials, and future prospects. Integrative Biology : Quantitative Biosciences From Nano to Macro. PMID 28045163 DOI: 10.1039/C6Ib00140H  0.555
2016 da Cunha NB, Cobacho NB, Viana JF, Lima LA, Sampaio KB, Dohms SS, Ferreira AC, de la Fuente-Núñez C, Costa FF, Franco OL, Dias SC. The next generation of antimicrobial peptides (AMPs) as molecular therapeutic tools for the treatment of diseases with social and economic impacts. Drug Discovery Today. PMID 27890668 DOI: 10.1016/j.drudis.2016.10.017  0.497
2016 Zhang T, Wang Z, Hancock RE, de la Fuente-Núñez C, Haapasalo M. Treatment of Oral Biofilms by a D-Enantiomeric Peptide. Plos One. 11: e0166997. PMID 27880799 DOI: 10.1371/journal.pone.0166997  0.36
2016 Silva ON, de la Fuente-Núñez C, Haney EF, Fensterseifer IC, Ribeiro SM, Porto WF, Brown P, Faria-Junior C, Rezende TM, Moreno SE, Lu TK, Hancock RE, Franco OL. An anti-infective synthetic peptide with dual antimicrobial and immunomodulatory activities. Scientific Reports. 6: 35465. PMID 27804992 DOI: 10.1038/Srep35465  0.672
2016 Mansour SC, Pletzer D, de la Fuente-Núñez C, Kim P, Cheung GY, Joo HS, Otto M, Hancock RE. Bacterial Abscess Formation Is Controlled by the Stringent Stress Response and Can Be Targeted Therapeutically. Ebiomedicine. PMID 27658736 DOI: 10.1016/J.Ebiom.2016.09.015  0.411
2016 Verderosa AD, Mansour SC, de la Fuente-Núñez C, Hancock RE, Fairfull-Smith KE. Synthesis and Evaluation of Ciprofloxacin-Nitroxide Conjugates as Anti-Biofilm Agents. Molecules (Basel, Switzerland). 21. PMID 27355936 DOI: 10.3390/molecules21070841  0.335
2016 Silva ON, Alves ES, de la Fuente-Núñez C, Ribeiro SM, Mandal SM, Gaspar D, Veiga AS, Castanho MA, Andrade CA, Nascimento JM, Fensterseifer IC, Porto WF, Correa JR, Hancock RE, Korpole S, et al. Structural Studies of a Lipid-Binding Peptide from Tunicate Hemocytes with Anti-Biofilm Activity. Scientific Reports. 6: 27128. PMID 27292548 DOI: 10.1038/srep27128  0.319
2016 Cardoso MH, Ribeiro SM, Nolasco DO, de la Fuente-Núñez C, Felício MR, Gonçalves S, Matos CO, Liao LM, Santos NC, Hancock RE, Franco OL, Migliolo L. A polyalanine peptide derived from polar fish with anti-infectious activities. Scientific Reports. 6: 21385. PMID 26916401 DOI: 10.1038/srep21385  0.452
2015 de la Fuente-Núñez C, Hancock RE. Using anti-biofilm peptides to treat antibiotic-resistant bacterial infections. Postdoc Journal : a Journal of Postdoctoral Research and Postdoctoral Affairs. 3: 1-8. PMID 27563687 DOI: 10.14304/surya.jpr.v3n2.1  0.476
2015 de la Fuente-Núñez C, Cardoso MH, de Souza Cândido E, Franco OL, Hancock RE. Synthetic antibiofilm peptides. Biochimica Et Biophysica Acta. PMID 26724202 DOI: 10.1016/j.bbamem.2015.12.015  0.518
2015 Bionda N, Fleeman RM, de la Fuente-Núñez C, Rodriguez MC, Reffuveille F, Shaw LN, Pastar I, Davis SC, Hancock RE, Cudic P. Identification of novel cyclic lipopeptides from a positional scanning combinatorial library with enhanced antibacterial and antibiofilm activities. European Journal of Medicinal Chemistry. 108: 354-363. PMID 26703794 DOI: 10.1016/J.Ejmech.2015.11.032  0.425
2015 Wang Z, de la Fuente-Núñez C, Shen Y, Haapasalo M, Hancock RE. Treatment of Oral Multispecies Biofilms by an Anti-Biofilm Peptide. Plos One. 10: e0132512. PMID 26168273 DOI: 10.1371/journal.pone.0132512  0.425
2015 Ribeiro SM, de la Fuente-Núñez C, Baquir B, Faria-Junior C, Franco OL, Hancock RE. Antibiofilm Peptides Increase the Susceptibility of Carbapenemase-Producing Klebsiella pneumoniae Clinical Isolates to β-Lactam Antibiotics. Antimicrobial Agents and Chemotherapy. 59: 3906-12. PMID 25896694 DOI: 10.1128/AAC.00092-15  0.44
2015 Haney EF, Mansour SC, Hilchie AL, de la Fuente-Núñez C, Hancock RE. High throughput screening methods for assessing antibiofilm and immunomodulatory activities of synthetic peptides. Peptides. PMID 25836992 DOI: 10.1016/j.peptides.2015.03.015  0.432
2015 Anunthawan T, de la Fuente-Núñez C, Hancock RE, Klaynongsruang S. Cationic amphipathic peptides KT2 and RT2 are taken up into bacterial cells and kill planktonic and biofilm bacteria. Biochimica Et Biophysica Acta. 1848: 1352-8. PMID 25767037 DOI: 10.1016/j.bbamem.2015.02.021  0.437
2015 de la Fuente-Núñez C, Reffuveille F, Mansour SC, Reckseidler-Zenteno SL, Hernández D, Brackman G, Coenye T, Hancock RE. D-enantiomeric peptides that eradicate wild-type and multidrug-resistant biofilms and protect against lethal Pseudomonas aeruginosa infections. Chemistry & Biology. 22: 196-205. PMID 25699603 DOI: 10.1016/j.chembiol.2015.01.002  0.468
2015 Mansour SC, de la Fuente-Núñez C, Hancock RE. Peptide IDR-1018: modulating the immune system and targeting bacterial biofilms to treat antibiotic-resistant bacterial infections. Journal of Peptide Science : An Official Publication of the European Peptide Society. 21: 323-9. PMID 25358509 DOI: 10.1002/psc.2708  0.487
2014 de la Fuente-Núñez C, Mansour SC, Wang Z, Jiang L, Breidenstein EB, Elliott M, Reffuveille F, Speert DP, Reckseidler-Zenteno SL, Shen Y, Haapasalo M, Hancock RE. Anti-Biofilm and Immunomodulatory Activities of Peptides That Inhibit Biofilms Formed by Pathogens Isolated from Cystic Fibrosis Patients. Antibiotics (Basel, Switzerland). 3: 509-526. PMID 26221537 DOI: 10.3390/Antibiotics3040509  0.423
2014 Reffuveille F, de la Fuente-Núñez C, Mansour S, Hancock RE. A broad-spectrum antibiofilm peptide enhances antibiotic action against bacterial biofilms. Antimicrobial Agents and Chemotherapy. 58: 5363-71. PMID 24982074 DOI: 10.1128/AAC.03163-14  0.47
2014 de la Fuente-Núñez C, Reffuveille F, Haney EF, Straus SK, Hancock RE. Broad-spectrum anti-biofilm peptide that targets a cellular stress response. Plos Pathogens. 10: e1004152. PMID 24852171 DOI: 10.1371/journal.ppat.1004152  0.432
2013 de la Fuente-Núñez C, Reffuveille F, Fernández L, Hancock RE. Bacterial biofilm development as a multicellular adaptation: antibiotic resistance and new therapeutic strategies. Current Opinion in Microbiology. 16: 580-9. PMID 23880136 DOI: 10.1016/j.mib.2013.06.013  0.358
2012 de la Fuente-Núñez C, Mertens J, Smit J, Hancock RE. The bacterial surface layer provides protection against antimicrobial peptides. Applied and Environmental Microbiology. 78: 5452-6. PMID 22635987 DOI: 10.1128/AEM.01493-12  0.36
2012 de la Fuente-Núñez C, Korolik V, Bains M, Nguyen U, Breidenstein EB, Horsman S, Lewenza S, Burrows L, Hancock RE. Inhibition of bacterial biofilm formation and swarming motility by a small synthetic cationic peptide. Antimicrobial Agents and Chemotherapy. 56: 2696-704. PMID 22354291 DOI: 10.1128/AAC.00064-12  0.452
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