| Year |
Citation |
Score |
| 2023 |
Kapustin A, Tsakali SS, Whitehead M, Chennell G, Wu MY, Molenaar C, Kutikhin A, Bogdanov L, Sinitsky M, Rubina K, Clayton A, Verweij FJ, Pegtel DM, Zingaro S, Lobov A, ... ... Shanahan CM, et al. Extracellular vesicles stimulate smooth muscle cell migration by presenting collagen VI. Biorxiv : the Preprint Server For Biology. PMID 37645762 DOI: 10.1101/2023.08.17.551257 |
0.301 |
|
| 2020 |
Duer M, Cobb AM, Shanahan CM. DNA Damage Response: A Molecular Lynchpin in the Pathobiology of Arteriosclerotic Calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. 40: e193-e202. PMID 32404005 DOI: 10.1161/ATVBAHA.120.313792 |
0.584 |
|
| 2020 |
Bansode S, Bashtanova U, Li R, Clark J, Müller KH, Puszkarska A, Goldberga I, Chetwood HH, Reid DG, Colwell LJ, Skepper JN, Shanahan CM, Schitter G, Mesquida P, Duer MJ. Glycation changes molecular organization and charge distribution in type I collagen fibrils. Scientific Reports. 10: 3397. PMID 32099005 DOI: 10.1038/S41598-020-60250-9 |
0.549 |
|
| 2019 |
Müller KH, Hayward R, Rajan R, Whitehead M, Cobb AM, Ahmad S, Sun M, Goldberga I, Li R, Bashtanova U, Puszkarska AM, Reid DG, Brooks RA, Skepper JN, Bordoloi J, ... ... Shanahan CM, et al. Poly(ADP-Ribose) Links the DNA Damage Response and Biomineralization. Cell Reports. 27: 3124-3138.e13. PMID 31189100 DOI: 10.1016/J.Celrep.2019.05.038 |
0.696 |
|
| 2019 |
Furmanik G, Chatrou M, Willems B, van Gorp R, Schmidt H, van Eys G, Bochaton-Piallat M, Proudfoot D, Biessen E, Hedin U, Matic LP, Mees B, Shanahan C, Reutelingsperger C, Schurgers L. Nox5 Regulates Vascular Smooth Muscle Cell Phenotype Atherosclerosis. 287: e27. DOI: 10.1016/J.Atherosclerosis.2019.06.079 |
0.339 |
|
| 2018 |
Bäck M, Aranyi T, Cancela ML, Carracedo M, Conceição N, Leftheriotis G, Macrae V, Martin L, Nitschke Y, Pasch A, Quaglino D, Rutsch F, Shanahan C, Sorribas V, Szeri F, et al. Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification: A Consensus Statement From the COST Action EuroSoftCalcNet. Frontiers in Cardiovascular Medicine. 5: 196. PMID 30713844 DOI: 10.3389/Fcvm.2018.00196 |
0.32 |
|
| 2018 |
Chow WY, Li R, Goldberga I, Reid DG, Rajan R, Clark J, Oschkinat H, Duer MJ, Hayward R, Shanahan CM. Essential but sparse collagen hydroxylysyl post-translational modifications detected by DNP NMR. Chemical Communications (Cambridge, England). PMID 30299444 DOI: 10.1039/C8Cc04960B |
0.675 |
|
| 2018 |
Whitehead M, Ahmad S, Shanahan C. 132 Role of vascular smooth muscle cell derived-exosomes in age-related vascular amyloidosis Heart. 104. DOI: 10.1136/Heartjnl-2018-Bcs.129 |
0.373 |
|
| 2018 |
Tsakali SS, Warren D, Shanahan C. P343The effect of matrix stiffness on vascular smooth muscle cell calcification Cardiovascular Research. 114: S88-S88. DOI: 10.1093/Cvr/Cvy060.256 |
0.374 |
|
| 2017 |
Li R, Rajan R, Wong WCV, Reid DG, Duer MJ, Somovilla VJ, Martinez-Saez N, Bernardes GJL, Hayward R, Shanahan CM. In situ characterization of advanced glycation end products (AGEs) in collagen and model extracellular matrix by solid state NMR. Chemical Communications (Cambridge, England). 53: 13316-13319. PMID 29192920 DOI: 10.1039/C7Cc06624D |
0.575 |
|
| 2017 |
Sun M, Cobb AM, Hayward R, Zhang QP, Duer M, Shroff R, Shanahan CM. 225 The role of the dna damage response in vascular calcification Heart. 103: A145.2-A146. DOI: 10.1136/heartjnl-2017-311726.223 |
0.541 |
|
| 2016 |
Dobrzynska A, Gonzalo S, Shanahan C, Askjaer P. The Nuclear Lamina in Health and Disease. Nucleus (Austin, Tex.). 0. PMID 27158763 DOI: 10.1080/19491034.2016.1183848 |
0.349 |
|
| 2016 |
Kapustin AN, Shanahan CM. Emerging roles for vascular smooth muscle cell exosomes in calcification and coagulation. The Journal of Physiology. PMID 26864864 DOI: 10.1113/JP271340 |
0.303 |
|
| 2015 |
Warren DT, Tajsic T, Porter LJ, Minaisah RM, Cobb A, Jacob A, Rajgor D, Zhang QP, Shanahan CM. Nesprin-2-dependent ERK1/2 compartmentalisation regulates the DNA damage response in vascular smooth muscle cell ageing. Cell Death and Differentiation. PMID 25744025 DOI: 10.1038/Cdd.2015.12 |
0.333 |
|
| 2015 |
Bordoloi JK, Berry D, Khan IU, Sunassee K, de Rosales RT, Shanahan C, Blower PJ. Technetium-99m and rhenium-188 complexes with one and two pendant bisphosphonate groups for imaging arterial calcification. Dalton Transactions (Cambridge, England : 2003). 44: 4963-75. PMID 25559039 DOI: 10.1039/C4Dt02965H |
0.325 |
|
| 2015 |
Zhu D, Mackenzie NC, Shanahan CM, Shroff RC, Farquharson C, MacRae VE. BMP-9 regulates the osteoblastic differentiation and calcification of vascular smooth muscle cells through an ALK1 mediated pathway. Journal of Cellular and Molecular Medicine. 19: 165-74. PMID 25297851 DOI: 10.1111/Jcmm.12373 |
0.309 |
|
| 2014 |
Chow WY, Rajan R, Muller KH, Reid DG, Skepper JN, Wong WC, Brooks RA, Green M, Bihan D, Farndale RW, Slatter DA, Shanahan CM, Duer MJ. NMR spectroscopy of native and in vitro tissues implicates polyADP ribose in biomineralization. Science (New York, N.Y.). 344: 742-6. PMID 24833391 DOI: 10.1126/science.1248167 |
0.665 |
|
| 2014 |
Lanzer P, Boehm M, Sorribas V, Thiriet M, Janzen J, Zeller T, St Hilaire C, Shanahan C. Medial vascular calcification revisited: review and perspectives. European Heart Journal. 35: 1515-25. PMID 24740885 DOI: 10.1093/Eurheartj/Ehu163 |
0.347 |
|
| 2014 |
Müller KH, Motskin M, Philpott AJ, Routh AF, Shanahan CM, Duer MJ, Skepper JN. The effect of particle agglomeration on the formation of a surface-connected compartment induced by hydroxyapatite nanoparticles in human monocyte-derived macrophages. Biomaterials. 35: 1074-88. PMID 24183166 DOI: 10.1016/j.biomaterials.2013.10.041 |
0.489 |
|
| 2014 |
Shanahan C. Mechanisms of vascular calcification Bone Abstracts. DOI: 10.1530/Boneabs.3.S3.1 |
0.335 |
|
| 2014 |
Shanahan C, Blower P, Bordoloi J. YIA1 Early Detection of the Process of Vascular Calcification with Spect-ct and Pet-ct using Novel Bone Seeking Radiopharmaceuticals in Rat Models Heart. 100: A122-A123. DOI: 10.1136/Heartjnl-2014-306118.225 |
0.305 |
|
| 2014 |
Laycock J, Shroff R, Shanahan C, Long D. 211 Examining the effects of Vitamin D Receptor Activators on Vascular Smooth Muscle Cell Calcification using Intact Vessels from Chronic Kidney Disease Patients Heart. 100: A116.1-A116. DOI: 10.1136/Heartjnl-2014-306118.211 |
0.351 |
|
| 2014 |
Kapustin A, Chatrou M, Kalra S, Drozdov I, Soong D, Furmanik M, Alvarez-Hernandez D, Shroff R, Yin X, Muller K, Skepper J, Mayr M, Sperger CR, Zheng Y, Davidson S, ... ... Shanahan C, et al. 162 Regulated Exosome Secretion by Vascular Smooth Muscle Cells Mediates Vascular Calcification Heart. 100: A93-A94. DOI: 10.1136/Heartjnl-2014-306118.162 |
0.374 |
|
| 2013 |
Reid DG, Duer MJ, Jackson GE, Murray RC, Rodgers AL, Shanahan CM. Citrate occurs widely in healthy and pathological apatitic biomineral: mineralized articular cartilage, and intimal atherosclerotic plaque and apatitic kidney stones. Calcified Tissue International. 93: 253-60. PMID 23780351 DOI: 10.1007/s00223-013-9751-5 |
0.613 |
|
| 2013 |
Shroff R, Long DA, Shanahan C. Mechanistic insights into vascular calcification in CKD. Journal of the American Society of Nephrology : Jasn. 24: 179-89. PMID 23138485 DOI: 10.1681/Asn.2011121191 |
0.408 |
|
| 2013 |
Kapustin A, Chatrou M, Drozdov I, Soong D, Furmanik M, Alvarez-Hernandez D, Sanchis P, Shroff R, Yin X, Skepper J, Mayr M, Reutelingsperger C, Schurgers L, Shanahan C. 192 MODULATED EXOSOME SECRETION BY VASCULAR SMOOTH MUSCLE CELLS IS A NOVEL REGULATORY MECHANISM OF VASCULAR CALCIFICATION Heart. 99: A107.2-A108. DOI: 10.1136/Heartjnl-2013-304019.192 |
0.421 |
|
| 2012 |
Kapustin AN, Shanahan CM. Calcium regulation of vascular smooth muscle cell-derived matrix vesicles. Trends in Cardiovascular Medicine. 22: 133-7. PMID 22902179 DOI: 10.1016/j.tcm.2012.07.009 |
0.334 |
|
| 2012 |
Reid DG, Shanahan CM, Duer MJ, Arroyo LG, Schoppet M, Brooks RA, Murray RC. Lipids in biocalcification: contrasts and similarities between intimal and medial vascular calcification and bone by NMR. Journal of Lipid Research. 53: 1569-75. PMID 22651923 DOI: 10.1194/jlr.M026088 |
0.571 |
|
| 2012 |
Proudfoot D, Shanahan C. Human vascular smooth muscle cell culture. Methods in Molecular Biology (Clifton, N.J.). 806: 251-63. PMID 22057457 DOI: 10.1007/978-1-61779-367-7_17 |
0.365 |
|
| 2011 |
Kapustin AN, Davies JD, Reynolds JL, McNair R, Jones GT, Sidibe A, Schurgers LJ, Skepper JN, Proudfoot D, Mayr M, Shanahan CM. Calcium regulates key components of vascular smooth muscle cell-derived matrix vesicles to enhance mineralization. Circulation Research. 109: e1-12. PMID 21566214 DOI: 10.1161/CIRCRESAHA.110.238808 |
0.308 |
|
| 2010 |
Shanahan C. Initiators and Inhibitors in Vascular Calcification Bone. 46: S14. DOI: 10.1016/J.Bone.2010.01.018 |
0.316 |
|
| 2008 |
Duer MJ, Friscić T, Proudfoot D, Reid DG, Schoppet M, Shanahan CM, Skepper JN, Wise ER. Mineral surface in calcified plaque is like that of bone: further evidence for regulated mineralization. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 2030-4. PMID 18703777 DOI: 10.1161/ATVBAHA.108.172387 |
0.563 |
|
| 2008 |
Shroff RC, Shah V, Hiorns MP, Schoppet M, Hofbauer LC, Hawa G, Schurgers LJ, Singhal A, Merryweather I, Brogan P, Shanahan C, Deanfield J, Rees L. The circulating calcification inhibitors, fetuin-A and osteoprotegerin, but not matrix Gla protein, are associated with vascular stiffness and calcification in children on dialysis. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 23: 3263-71. PMID 18463323 DOI: 10.1093/Ndt/Gfn226 |
0.36 |
|
| 2008 |
Schoppet M, Shroff RC, Hofbauer LC, Shanahan CM. Exploring the biology of vascular calcification in chronic kidney disease: What's circulating? Kidney International. 73: 384-390. PMID 18046319 DOI: 10.1038/Sj.Ki.5002696 |
0.389 |
|
| 2008 |
Schoppet M, Shanahan C. Role for alkaline phosphatase as an inducer of vascular calcification in renal failure? Kidney International. 73: 989-991. DOI: 10.1038/Ki.2008.104 |
0.333 |
|
| 2007 |
Shroff RC, Shanahan CM. The vascular biology of calcification Seminars in Dialysis. 20: 103-109. PMID 17374082 DOI: 10.1111/j.1525-139X.2007.00255.x |
0.361 |
|
| 2006 |
Hofbauer LC, Brueck CC, Shanahan CM, Schoppet M, Dobnig H. Vascular calcification and osteoporosis--from clinical observation towards molecular understanding. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 18: 251-9. PMID 17151836 DOI: 10.1007/S00198-006-0282-Z |
0.412 |
|
| 2005 |
Shanahan CM. Mechanisms of vascular calcification in renal disease. Clinical Nephrology. 63: 146-57. PMID 15730057 DOI: 10.5414/CNP63146 |
0.35 |
|
| 2004 |
Qasim A, Weissberg P, Shanahan C. INHIBITORY SMADS REGULATE VASCULAR SMOOTH MUSCLE CELL AND BONE MARROW STROMAL CELL PHENOTYPE Cardiovascular Pathology. 13: 162. DOI: 10.1016/J.Carpath.2004.03.488 |
0.39 |
|
| 2004 |
Davies J, Carpenter K, Figg N, Challis I, Weissberg P, Shanahan C. HUMAN VASCULAR SMOOTH MUSCLE CELLS EXHIBIT DE NOVO SYNTHESIS OF TRIACYLGLYCEROL VIA TWO PATHWAYS Cardiovascular Pathology. 13: 27. DOI: 10.1016/J.Carpath.2004.03.074 |
0.333 |
|
| 2001 |
Farzaneh-Far A, Proudfoot D, Shanahan C, Weissberg PL. Vascular and valvar calcification: recent advances. Heart. 85: 13-17. PMID 11119453 DOI: 10.1136/Heart.85.1.13 |
0.309 |
|
| 1995 |
Adam P, Weissberg P, Shanahan C. Identification and Characterisation of a Polyubiquitin Transcript Differentially Expressed in Rat and Human Vascular Smooth Muscle Cells Clinical Science. 89: 5P-5P. DOI: 10.1042/Cs089005Pa |
0.314 |
|
| Low-probability matches (unlikely to be authored by this person) |
| 2018 |
Bautista-Nino PK, Portilla-Fernandez E, Santu A, Shanahan C, Roks A. Abstract 059: Local Endothelial and Smooth Muscle Genomic Instability Reproduce Specific Features of Cardiovascular Aging Hypertension. 72. DOI: 10.1161/Hyp.72.Suppl_1.059 |
0.299 |
|
| 1995 |
Connolly D, Monard S, Shanahan C, Weissberg P. Osmotically Driven Vascular Smooth Muscle Cell Membrane Water Transport is Inhibitable by Mercuric Chloride Clinical Science. 88: 19P-19P. DOI: 10.1042/Cs088019P |
0.296 |
|
| 2019 |
Infante E, Stannard A, Board SJ, Rico-Lastres P, Rostkova E, Beedle AEM, Lezamiz A, Wang YJ, Gulaidi Breen S, Panagaki F, Sundar Rajan V, Shanahan C, Roca-Cusachs P, Garcia-Manyes S. The mechanical stability of proteins regulates their translocation rate into the cell nucleus Nature Physics. 15: 973-981. DOI: 10.1038/S41567-019-0551-3 |
0.296 |
|
| 2011 |
Kapustin A, Galkin A, Furmanik M, Alvarez-Hernandez D, Shanahan C. 19 Elevated calcium and phosphate impair mitochondrial function in calcifying human vascular smooth muscle cell Heart. 97: e8-e8. DOI: 10.1136/Heartjnl-2011-301156.19 |
0.295 |
|
| 2006 |
Proudfoot D, Shanahan CM. Molecular mechanisms mediating vascular calcification: role of matrix Gla protein. Nephrology (Carlton, Vic.). 11: 455-61. PMID 17014561 DOI: 10.1111/j.1440-1797.2006.00660.x |
0.292 |
|
| 2015 |
Brayson D, Protti A, Ehler E, Vizcay G, Warley A, Shah AM, Shanahan C. 167 The pathogenic implications of prelamin a accumulation in cardiomyocytes: a model of premature cardiac senescence? Heart. 101: A95.1-A95. DOI: 10.1136/Heartjnl-2015-308066.167 |
0.292 |
|
| 2018 |
Durham AL, Speer MY, Scatena M, Giachelli CM, Shanahan CM. Role of smooth muscle cells in vascular calcification: implications in atherosclerosis and arterial stiffness. Cardiovascular Research. 114: 590-600. PMID 29514202 DOI: 10.1093/Cvr/Cvy010 |
0.288 |
|
| 2024 |
Faleeva M, Ahmad S, Theofilatos K, Lynham S, Watson G, Whitehead M, Marhuenda E, Iskratsch T, Cox S, Shanahan CM. Sox9 Accelerates Vascular Ageing by Regulating Extracellular Matrix Composition and Stiffness. Circulation Research. PMID 38179698 DOI: 10.1161/CIRCRESAHA.123.323365 |
0.282 |
|
| 2011 |
Nikolova-Krstevski V, Leimena C, Xiao XH, Kesteven S, Tan JC, Yeo LS, Yu ZY, Zhang Q, Carlton A, Head S, Shanahan C, Feneley MP, Fatkin D. Nesprin-1 and actin contribute to nuclear and cytoskeletal defects in lamin A/C-deficient cardiomyopathy. Journal of Molecular and Cellular Cardiology. 50: 479-86. PMID 21156181 DOI: 10.1016/J.Yjmcc.2010.12.001 |
0.282 |
|
| 2011 |
Schoppet M, Kavurma MM, Hofbauer LC, Shanahan CM. Crystallizing nanoparticles derived from vascular smooth muscle cells contain the calcification inhibitor osteoprotegerin. Biochemical and Biophysical Research Communications. 407: 103-7. PMID 21371424 DOI: 10.1016/j.bbrc.2011.02.117 |
0.281 |
|
| 2011 |
Proudfoot D, Shanahan CM. Nanocrystals seed calcification in more ways than one. Kidney International. 79: 379-82. PMID 21278777 DOI: 10.1038/ki.2010.455 |
0.278 |
|
| 2015 |
Kapustin AN, Chatrou ML, Drozdov I, Zheng Y, Davidson SM, Soong D, Furmanik M, Sanchis P, De Rosales RT, Alvarez-Hernandez D, Shroff R, Yin X, Muller K, Skepper JN, Mayr M, ... ... Shanahan CM, et al. Vascular smooth muscle cell calcification is mediated by regulated exosome secretion. Circulation Research. 116: 1312-23. PMID 25711438 DOI: 10.1161/CIRCRESAHA.116.305012 |
0.273 |
|
| 2013 |
Shanahan CM. Autophagy and matrix vesicles: new partners in vascular calcification. Kidney International. 83: 984-6. PMID 23727998 DOI: 10.1038/ki.2013.75 |
0.273 |
|
| 2013 |
Brayson D, Shah AM, Shanahan C. 218 A TRANSGENIC MODEL OF PRELAMIN A ACCUMULATION LEADS TO CARDIAC DYSFUNCTION IN MICE Heart. 99: A119.1-A119. DOI: 10.1136/Heartjnl-2013-304019.218 |
0.268 |
|
| 2017 |
Ter Braake AD, Shanahan CM, de Baaij JHF. Magnesium Counteracts Vascular Calcification: Passive Interference or Active Modulation? Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28663256 DOI: 10.1161/ATVBAHA.117.309182 |
0.267 |
|
| 2003 |
Hegyi L, Gannon FH, Glaser DL, Shore EM, Kaplan FS, Shanahan CM. Stromal cells of fibrodysplasia ossificans progressiva lesions express smooth muscle lineage markers and the osteogenic transcription factor Runx2/Cbfa-1: clues to a vascular origin of heterotopic ossification? The Journal of Pathology. 201: 141-8. PMID 12950027 DOI: 10.1002/Path.1413 |
0.265 |
|
| 2013 |
Liu Y, Drozdov I, Shroff R, Beltran LE, Shanahan CM. Prelamin A accelerates vascular calcification via activation of the DNA damage response and senescence-associated secretory phenotype in vascular smooth muscle cells. Circulation Research. 112: e99-109. PMID 23564641 DOI: 10.1161/CIRCRESAHA.111.300543 |
0.265 |
|
| 1993 |
Shanahan CM, Weissberg PL, Metcalfe JC. Isolation of gene markers of differentiated and proliferating vascular smooth muscle cells. Circulation Research. 73: 193-204. PMID 8508530 DOI: 10.1161/01.RES.73.1.193 |
0.265 |
|
| 2006 |
Crisp M, Liu Q, Roux K, Rattner JB, Shanahan C, Burke B, Stahl PD, Hodzic D. Coupling of the nucleus and cytoplasm: role of the LINC complex. The Journal of Cell Biology. 172: 41-53. PMID 16380439 DOI: 10.1083/Jcb.200509124 |
0.264 |
|
| 2018 |
Ter Braake AD, Tinnemans PT, Shanahan CM, Hoenderop JGJ, de Baaij JHF. Magnesium prevents vascular calcification in vitro by inhibition of hydroxyapatite crystal formation. Scientific Reports. 8: 2069. PMID 29391410 DOI: 10.1038/s41598-018-20241-3 |
0.263 |
|
| 2017 |
Kapustin AN, Schoppet M, Schurgers LJ, Reynolds JL, McNair R, Heiss A, Jahnen-Dechent W, Hackeng TM, Schlieper G, Harrison P, Shanahan CM. Prothrombin Loading of Vascular Smooth Muscle Cell-Derived Exosomes Regulates Coagulation and Calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 28104608 DOI: 10.1161/Atvbaha.116.308886 |
0.262 |
|
| 2011 |
Warren DT, Shanahan CM. Defective DNA-damage repair induced by nuclear lamina dysfunction is a key mediator of smooth muscle cell aging. Biochemical Society Transactions. 39: 1780-5. PMID 22103525 DOI: 10.1042/BST20110703 |
0.261 |
|
| 2012 |
Tyson K, Shanahan C. Use of cDNA representational difference analysis to identify disease-specific genes in human atherosclerotic plaques. Methods in Molecular Medicine. 30: 83-98. PMID 21341018 DOI: 10.1385/1-59259-247-3:83 |
0.257 |
|
| 2009 |
Kapustin A, Shanahan CM. Targeting vascular calcification: softening-up a hard target. Current Opinion in Pharmacology. 9: 84-9. PMID 19157979 DOI: 10.1016/j.coph.2008.12.004 |
0.257 |
|
| 2005 |
Reynolds JL, Skepper JN, McNair R, Kasama T, Gupta K, Weissberg PL, Jahnen-Dechent W, Shanahan CM. Multifunctional roles for serum protein fetuin-a in inhibition of human vascular smooth muscle cell calcification. Journal of the American Society of Nephrology : Jasn. 16: 2920-30. PMID 16093453 DOI: 10.1681/Asn.2004100895 |
0.254 |
|
| 2005 |
Burke B, Shanahan C, Salina D, Crisp M. Aspects of nuclear envelope dynamics in mitotic cells. Novartis Foundation Symposium. 264: 22-34. DOI: 10.1002/0470093765.Ch3 |
0.254 |
|
| 2014 |
Zhou C, Li C, Zhou B, Rao L, McNally E, Shanahan C, Zhang Q. NOVEL NESPRIN-1 MUTATIONS DISRUPT NE ORGANIZATION AND INDUCE DILATED CARDIOMYOPATHY Heart. 100: A19.1-A19. DOI: 10.1136/Heartjnl-2014-306916.56 |
0.253 |
|
| 2001 |
Proudfoot D, Shanahan CM. Biology of calcification in vascular cells: intima versus media. Herz. 26: 245-51. PMID 11479936 DOI: 10.1007/PL00002027 |
0.252 |
|
| 2004 |
Reynolds JL, Joannides AJ, Skepper JN, Mcnair R, Schurgers LJ, Proudfoot D, Jahnen-Dechent W, Weissberg PL, Shanahan CM. Human vascular smooth muscle cells undergo vesicle-mediated calcification in response to changes in extracellular calcium and phosphate concentrations: A potential mechanism for accelerated vascular calcification in ESRD Journal of the American Society of Nephrology. 15: 2857-2867. PMID 15504939 DOI: 10.1097/01.ASN.0000141960.01035.28 |
0.25 |
|
| 2004 |
Reynolds J, Proudfoot D, Skepper J, McNair R, Johannides A, Weissberg P, Shanahan C. MINERAL ION-INDUCED RELEASE OF MINERALIZATION-COMPETENT MATRIX VESICLES FROM HUMAN VASCULAR SMOOTH MUSCLE CELLS Cardiovascular Pathology. 13: 186. DOI: 10.1016/J.CARPATH.2004.03.560 |
0.248 |
|
| 2004 |
Reynolds J, Proudfoot D, Skepper J, McNair R, Johannides A, Weissberg P, Shanahan C. MINERAL ION-INDUCED RELEASE OF MINERALIZATION-COMPETENT MATRIX VESICLES FROM HUMAN VASCULAR SMOOTH MUSCLE CELLS Cardiovascular Pathology. 13: 183. DOI: 10.1016/J.CARPATH.2004.03.550 |
0.248 |
|
| 2003 |
Tyson KL, Reynolds JL, McNair R, Zhang Q, Weissberg PL, Shanahan CM. Osteo/chondrocytic transcription factors and their target genes exhibit distinct patterns of expression in human arterial calcification Arteriosclerosis, Thrombosis, and Vascular Biology. 23: 489-494. PMID 12615658 DOI: 10.1161/01.ATV.0000059406.92165.31 |
0.248 |
|
| 2018 |
Furmanik M, Shanahan CM. ER stress regulates alkaline phosphatase gene expression in vascular smooth muscle cells via an ATF4-dependent mechanism. Bmc Research Notes. 11: 483. PMID 30012221 DOI: 10.1186/s13104-018-3582-4 |
0.248 |
|
| 2012 |
Kalra SS, Shanahan CM. Vascular calcification and hypertension: cause and effect. Annals of Medicine. 44: S85-92. PMID 22713153 DOI: 10.3109/07853890.2012.660498 |
0.247 |
|
| 2022 |
Whitehead M, Yusoff S, Ahmad S, Schmidt L, Mayr M, Madine J, Middleton D, Shanahan CM. Vascular smooth muscle cell senescence accelerates medin aggregation via small extracellular vesicle secretion and extracellular matrix reorganization. Aging Cell. e13746. PMID 36433666 DOI: 10.1111/acel.13746 |
0.246 |
|
| 2001 |
Greaves DR, Häkkinen T, Lucas AD, Liddiard K, Jones E, Quinn CM, Senaratne J, Green FR, Tyson K, Boyle J, Shanahan C, Weissberg PL, Gordon S, Ylä-Hertualla S. Linked chromosome 16q13 chemokines, macrophage-derived chemokine, fractalkine, and thymus- and activation-regulated chemokine, are expressed in human atherosclerotic lesions. Arteriosclerosis, Thrombosis, and Vascular Biology. 21: 923-9. PMID 11397698 DOI: 10.1161/01.Atv.21.6.923 |
0.246 |
|
| 2017 |
Shanahan CM, Furmanik M. Endoplasmic Reticulum Stress in Arterial Smooth Muscle Cells: A Novel Regulator of Vascular Disease. Current Cardiology Reviews. 13: 94-105. PMID 27758694 DOI: 10.2174/1573403X12666161014094738 |
0.245 |
|
| 2013 |
Shanahan CM. Mechanisms of vascular calcification in CKD-evidence for premature ageing? Nature Reviews. Nephrology. 9: 661-70. PMID 24018414 DOI: 10.1038/nrneph.2013.176 |
0.243 |
|
| 1999 |
Shanahan CM, Cary NR, Salisbury JR, Proudfoot D, Weissberg PL, Edmonds ME. Medial localization of mineralization-regulating proteins in association with Mönckeberg's sclerosis: evidence for smooth muscle cell-mediated vascular calcification. Circulation. 100: 2168-76. PMID 10571976 DOI: 10.1161/01.CIR.100.21.2168 |
0.24 |
|
| 2011 |
Liu Y, Shanahan CM. 1 Prelamin A promotes DNA damage, calcification and senescence in human vascular smooth muscle cells Heart. 97: e7-e7. DOI: 10.1136/heartjnl-2011-300920b.1 |
0.239 |
|
| 2005 |
Enis DR, Shepherd BR, Wang Y, Qasim A, Shanahan CM, Weissberg PL, Kashgarian M, Pober JS, Schechner JS. Induction, differentiation, and remodeling of blood vessels after transplantation of Bcl-2-transduced endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 102: 425-30. PMID 15625106 DOI: 10.1073/Pnas.0408357102 |
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| 2013 |
Petrova NL, Shanahan CM. Neuropathy and the vascular-bone axis in diabetes: lessons from Charcot osteoarthropathy. Osteoporosis International : a Journal Established as Result of Cooperation Between the European Foundation For Osteoporosis and the National Osteoporosis Foundation of the Usa. 25: 1197-207. PMID 24091593 DOI: 10.1007/s00198-013-2511-6 |
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| 2021 |
Lust ST, Shanahan CM, Shipley RJ, Lamata P, Gentleman E. Design considerations for engineering 3D models to study vascular pathologies in vitro. Acta Biomaterialia. PMID 33652164 DOI: 10.1016/j.actbio.2021.02.031 |
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| 2010 |
Shroff RC, McNair R, Skepper JN, Figg N, Schurgers LJ, Deanfield J, Rees L, Shanahan CM. Chronic mineral dysregulation promotes vascular smooth muscle cell adaptation and extracellular matrix calcification. Journal of the American Society of Nephrology : Jasn. 21: 103-12. PMID 19959717 DOI: 10.1681/ASN.2009060640 |
0.235 |
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| 2016 |
Cobb AM, Larrieu D, Warren DT, Liu Y, Srivastava S, Smith AJ, Bowater RP, Jackson SP, Shanahan CM. Prelamin A impairs 53BP1 nuclear entry by mislocalizing NUP153 and disrupting the Ran gradient. Aging Cell. PMID 27464478 DOI: 10.1111/acel.12506 |
0.234 |
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| 2010 |
Ragnauth CD, Warren DT, Liu Y, McNair R, Tajsic T, Figg N, Shroff R, Skepper J, Shanahan CM. Prelamin A acts to accelerate smooth muscle cell senescence and is a novel biomarker of human vascular aging. Circulation. 121: 2200-10. PMID 20458013 DOI: 10.1161/CIRCULATIONAHA.109.902056 |
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| 2013 |
Heistad DD, Shanahan C, Demer LL. Introduction to the Compendium on calcific aortic valve disease. Circulation Research. 113: 176-8. PMID 23833291 DOI: 10.1161/Circresaha.113.301833 |
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| 1998 |
Shanahan CM, Cary NR, Osbourn JK, Weissberg PL. Identification of osteoglycin as a component of the vascular matrix. Differential expression by vascular smooth muscle cells during neointima formation and in atherosclerotic plaques. Arteriosclerosis, Thrombosis, and Vascular Biology. 17: 2437-47. PMID 9409213 DOI: 10.1161/01.ATV.17.11.2437 |
0.231 |
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| 2020 |
Cobb AM, Yusoff S, Hayward R, Ahmad S, Sun M, Verhulst A, D'Haese PC, Shanahan CM. Runx2 (Runt-Related Transcription Factor 2) Links the DNA Damage Response to Osteogenic Reprogramming and Apoptosis of Vascular Smooth Muscle Cells. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315206. PMID 33356386 DOI: 10.1161/ATVBAHA.120.315206 |
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| 2019 |
Sanchis P, Ho CY, Liu Y, Beltran LE, Ahmad S, Jacob AP, Furmanik M, Laycock J, Long DA, Shroff R, Shanahan CM. Arterial "inflammaging" drives vascular calcification in children on dialysis. Kidney International. PMID 30827513 DOI: 10.1016/j.kint.2018.12.014 |
0.23 |
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| 2011 |
Di Bartolo BA, Schoppet M, Mattar MZ, Rachner TD, Shanahan CM, Kavurma MM. Calcium and osteoprotegerin regulate IGF1R expression to inhibit vascular calcification. Cardiovascular Research. 91: 537-45. PMID 21447702 DOI: 10.1093/cvr/cvr084 |
0.23 |
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| 2000 |
Shanahan CM, Weissberg PL. Smooth muscle cell phenotypes in atherosclerotic lesions. Current Opinion in Lipidology. 10: 507-13. PMID 10680044 DOI: 10.1097/00041433-199912000-00005 |
0.23 |
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| 2005 |
Farzaneh-Far A, Shanahan CM. Biology of vascular calcification in renal disease. Nephron. Experimental Nephrology. 101: e134-8. PMID 16113585 DOI: 10.1159/000087578 |
0.23 |
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| 2018 |
Dusso A, Colombo MI, Shanahan CM. Not all vascular smooth muscle cell exosomes calcify equally in chronic kidney disease. Kidney International. 93: 298-301. PMID 29389393 DOI: 10.1016/j.kint.2017.08.036 |
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| 2023 |
Whitehead M, Antonazzi M, Shanahan CM. Senescence and extracellular vesicles: novel partners in vascular amyloidosis. Aging. 15: 1232-1234. PMID 36863314 DOI: 10.18632/aging.204571 |
0.228 |
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| 2022 |
Sutton NR, Malhotra R, Hilaire CS, Aikawa E, Blumenthal RS, Gackenbach G, Goyal P, Johnson A, Nigwekar SU, Shanahan CM, Towler DA, Wolford BN, Chen Y. Molecular Mechanisms of Vascular Health: Insights From Vascular Aging and Calcification. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 36412195 DOI: 10.1161/ATVBAHA.122.317332 |
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| 1999 |
Shanahan CM, Connolly DL, Tyson KL, Cary NR, Osbourn JK, Agre P, Weissberg PL. Aquaporin-1 is expressed by vascular smooth muscle cells and mediates rapid water transport across vascular cell membranes. Journal of Vascular Research. 36: 353-62. PMID 10559675 DOI: 10.1159/000025674 |
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| 2020 |
Sorokin V, Vickneson K, Kofidis T, Woo CC, Lin XY, Foo R, Shanahan CM. Role of Vascular Smooth Muscle Cell Plasticity and Interactions in Vessel Wall Inflammation. Frontiers in Immunology. 11: 599415. PMID 33324416 DOI: 10.3389/fimmu.2020.599415 |
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| 2016 |
Porter LJ, Holt MR, Soong D, Shanahan CM, Warren DT. Prelamin A Accumulation Attenuates Rac1 Activity and Increases the Intrinsic Migrational Persistence of Aged Vascular Smooth Muscle Cells. Cells. 5. PMID 27854297 DOI: 10.3390/cells5040041 |
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| 2008 |
Shroff RC, McNair R, Figg N, Skepper JN, Schurgers L, Gupta A, Hiorns M, Donald AE, Deanfield J, Rees L, Shanahan CM. Dialysis accelerates medial vascular calcification in part by triggering smooth muscle cell apoptosis. Circulation. 118: 1748-57. PMID 18838561 DOI: 10.1161/CIRCULATIONAHA.108.783738 |
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| 2020 |
Porter L, Minaisah RM, Ahmed S, Ali S, Norton R, Zhang Q, Ferraro E, Molenaar C, Holt M, Cox S, Fountain S, Shanahan C, Warren D. SUN1/2 Are Essential for RhoA/ROCK-Regulated Actomyosin Activity in Isolated Vascular Smooth Muscle Cells. Cells. 9. PMID 31935926 DOI: 10.3390/cells9010132 |
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| 2013 |
Liu Y, Sanchis P, Shroff R, Furmanik M, Kapustin A, Jacob AP, Shanahan CM. 174 DNA DAMAGE IN VASCULAR SMOOTH MUSCLE CELLS PROMOTES PREMATURE AGEING AND ARTERIAL CALCIFICATION IN CHILDREN ON DIALYSIS Heart. 99: A100.1-A100. DOI: 10.1136/heartjnl-2013-304019.174 |
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| 2011 |
Liu Y, Shanahan CM. Signalling pathways and vascular calcification. Frontiers in Bioscience (Landmark Edition). 16: 1302-14. PMID 21196233 DOI: 10.2741/3790 |
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| 2014 |
Petrova N, Petrov P, Edmonds M, Shanahan C. The role of IL-6 as a modulator of osteoclastic resorption in vitro in acute Charcot osteoarthropathy Bone Abstracts. DOI: 10.1530/Boneabs.3.Pp162 |
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| 2003 |
King KE, Iyemere VP, Weissberg PL, Shanahan CM. Krüppel-like factor 4 (KLF4/GKLF) is a target of bone morphogenetic proteins and transforming growth factor beta 1 in the regulation of vascular smooth muscle cell phenotype. The Journal of Biological Chemistry. 278: 11661-9. PMID 12538588 DOI: 10.1074/jbc.M211337200 |
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| 2005 |
Shanahan CM. Vascular calcification. Current Opinion in Nephrology and Hypertension. 14: 361-7. PMID 15931005 DOI: 10.1097/01.mnh.0000172723.52499.38 |
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| 2020 |
Furmanik M, Chatrou M, van Gorp RH, Akbulut A, Willems B, Schmidt HH, van Eys G, Bochaton-Piallat ML, Proudfoot D, Biessen EA, Hedin U, Matic L, Mees B, Shanahan CM, Reutelingsperger C, et al. Reactive Oxygen-Forming Nox5 Links Vascular Smooth Muscle Cell Phenotypic Switching and Extracellular Vesicle-Mediated Vascular Calcification. Circulation Research. PMID 32564697 DOI: 10.1161/CIRCRESAHA.119.316159 |
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| 2013 |
Rajgor D, Shanahan CM. Nesprins: from the nuclear envelope and beyond. Expert Reviews in Molecular Medicine. 15: e5. PMID 23830188 DOI: 10.1017/erm.2013.6 |
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| 2008 |
Ewence AE, Bootman M, Roderick HL, Skepper JN, McCarthy G, Epple M, Neumann M, Shanahan CM, Proudfoot D. Calcium phosphate crystals induce cell death in human vascular smooth muscle cells: a potential mechanism in atherosclerotic plaque destabilization. Circulation Research. 103: e28-34. PMID 18669918 DOI: 10.1161/CIRCRESAHA.108.181305 |
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| 2005 |
Davies JD, Carpenter KL, Challis IR, Figg NL, McNair R, Proudfoot D, Weissberg PL, Shanahan CM. Adipocytic differentiation and liver x receptor pathways regulate the accumulation of triacylglycerols in human vascular smooth muscle cells. The Journal of Biological Chemistry. 280: 3911-9. PMID 15548517 DOI: 10.1074/jbc.M410075200 |
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| 1993 |
Shanahan C, Carey N, Metcalfe J, Weissberg P. Isolation of Novel Markers of Differentiated and Proliferating Vascular Smooth Muscle Cells Clinical Science. 84: 3P-3P. DOI: 10.1042/CS084003PB |
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| 2011 |
Shanahan CM, Crouthamel MH, Kapustin A, Giachelli CM. Arterial calcification in chronic kidney disease: key roles for calcium and phosphate. Circulation Research. 109: 697-711. PMID 21885837 DOI: 10.1161/Circresaha.110.234914 |
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| 1998 |
Shanahan CM, Weissberg PL. Smooth muscle cell heterogeneity: patterns of gene expression in vascular smooth muscle cells in vitro and in vivo. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 333-8. PMID 9514400 DOI: 10.1161/01.ATV.18.3.333 |
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| 2015 |
Niño PK, Durik M, Danser AH, de Vries R, Musterd-Bhaggoe UM, Meima ME, Kavousi M, Ghanbari M, Hoeijmakers JH, O'Donnell CJ, Franceschini N, Janssen GM, De Mey JG, Liu Y, Shanahan CM, et al. Phosphodiesterase 1 regulation is a key mechanism in vascular aging. Clinical Science (London, England : 1979). 129: 1061-75. PMID 26464516 DOI: 10.1042/CS20140753 |
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| 2023 |
De Silva S, Fan Z, Kang B, Shanahan CM, Zhang Q. Nesprin-1: novel regulator of striated muscle nuclear positioning and mechanotransduction. Biochemical Society Transactions. PMID 37171063 DOI: 10.1042/BST20221541 |
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| 2021 |
Roks AJM, Cheng C, Shanahan CM. Notch-Rho-cGMP interaction: common point of convergence in microvascular aging-related disease. Clinical Science (London, England : 1979). 135: 1209-1212. PMID 34014259 DOI: 10.1042/CS20210288 |
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| 2018 |
Infante E, Castagnino A, Ferrari R, Monteiro P, Agüera-González S, Paul-Gilloteaux P, Domingues MJ, Maiuri P, Raab M, Shanahan CM, Baffet A, Piel M, Gomes ER, Chavrier P. LINC complex-Lis1 interplay controls MT1-MMP matrix digest-on-demand response for confined tumor cell migration. Nature Communications. 9: 2443. PMID 29934494 DOI: 10.1038/S41467-018-04865-7 |
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| 2013 |
New SEP, Goettsch C, Aikawa M, Marchini JF, Shibasaki M, Yabusaki K, Libby P, Shanahan CM, Croce K, Aikawa E. Macrophage-derived matrix vesicles : An alternative novel mechanism for microcalcification in atherosclerotic plaques Circulation Research. 113: 72-77. PMID 23616621 DOI: 10.1161/CIRCRESAHA.113.301036 |
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| 2012 |
Petrova⁎ N, Petrov P, Edmonds M, Shanahan C. Measurement of depth and profile of resorption pits on bovine discs using Dektak 150 Surface Profiler Bone. 50: S92. DOI: 10.1016/J.Bone.2012.02.274 |
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| 2018 |
Zhou C, Rao L, Warren DT, Shanahan CM, Zhang Q. Mouse models of nesprin-related diseases. Biochemical Society Transactions. PMID 29784648 DOI: 10.1042/BST20180085 |
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| 2023 |
Evenepoel P, Stenvinkel P, Shanahan C, Pacifici R. Inflammation and gut dysbiosis as drivers of CKD-MBD. Nature Reviews. Nephrology. 19: 646-657. PMID 37488276 DOI: 10.1038/s41581-023-00736-7 |
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| 2020 |
Furmanik M, van Gorp R, Whitehead M, Ahmad S, Bordoloi J, Kapustin A, Schurgers LJ, Shanahan CM. Endoplasmic Reticulum Stress Mediates Vascular Smooth Muscle Cell Calcification via Increased Release of Grp78-Loaded Extracellular Vesicles. Arteriosclerosis, Thrombosis, and Vascular Biology. ATVBAHA120315506. PMID 33297752 DOI: 10.1161/ATVBAHA.120.315506 |
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| 2007 |
Zhang Q, Bethmann C, Worth NF, Davies JD, Wasner C, Feuer A, Ragnauth CD, Yi Q, Mellad JA, Warren DT, Wheeler MA, Ellis JA, Skepper JN, Vorgerd M, Schlotter-Weigel B, ... ... Shanahan CM, et al. Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity. Human Molecular Genetics. 16: 2816-33. PMID 17761684 DOI: 10.1093/hmg/ddm238 |
0.19 |
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| 2014 |
King SJ, Nowak K, Suryavanshi N, Holt I, Shanahan CM, Ridley AJ. Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration. Cytoskeleton (Hoboken, N.J.). 71: 423-34. PMID 24931616 DOI: 10.1002/cm.21182 |
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| 2017 |
Dautova Y, Kapustin AN, Pappert K, Epple M, Okkenhaug H, Cook SJ, Shanahan CM, Bootman MD, Proudfoot D. Calcium phosphate particles stimulate interleukin-1β release from human vascular smooth muscle cells: A role for spleen tyrosine kinase and exosome release. Journal of Molecular and Cellular Cardiology. PMID 29274344 DOI: 10.1016/j.yjmcc.2017.12.007 |
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| 2017 |
Brayson D, Shanahan CM. Current insights into LMNA cardiomyopathies: Existing models and missing LINCs. Nucleus (Austin, Tex.). 8: 17-33. PMID 28125396 DOI: 10.1080/19491034.2016.1260798 |
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| 2022 |
Brayson D, Shanahan CM. Lamin A precursor localizes to the Z-disc of sarcomeres in the heart and is dynamically regulated in muscle cell differentiation. Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences. 377: 20210490. PMID 36189817 DOI: 10.1098/rstb.2021.0490 |
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| 2006 |
Shanahan CM. Vascular calcification--a matter of damage limitation? Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 21: 1166-9. PMID 16522660 DOI: 10.1093/ndt/gfl089 |
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| 2014 |
Shroff R, Speer T, Colin S, Charakida M, Zewinger S, Staels B, Chinetti-Gbaguidi G, Hettrich I, Rohrer L, O'Neill F, McLoughlin E, Long D, Shanahan CM, Landmesser U, Fliser D, et al. HDL in children with CKD promotes endothelial dysfunction and an abnormal vascular phenotype. Journal of the American Society of Nephrology : Jasn. 25: 2658-68. PMID 24854267 DOI: 10.1681/ASN.2013111212 |
0.181 |
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| 2016 |
Ho CY, Shanahan CM. Medial Arterial Calcification: An Overlooked Player in Peripheral Arterial Disease. Arteriosclerosis, Thrombosis, and Vascular Biology. PMID 27312224 DOI: 10.1161/ATVBAHA.116.306717 |
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| 2000 |
Shanahan C, Proudfoot D, Tyson K, Cary N, Edmonds M, Weissberg P. Expression of mineralisation-regulating proteins in association with human vascular calcification Zeitschrift F�R Kardiologie. 89: S063-S068. DOI: 10.1007/s003920070101 |
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| 2018 |
Zhou C, Rao L, Shanahan CM, Zhang Q. Nesprin-1/2: roles in nuclear envelope organisation, myogenesis and muscle disease. Biochemical Society Transactions. PMID 29487227 DOI: 10.1042/BST20170149 |
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| 2017 |
Suna G, Wojakowski W, Lynch M, Barallobre-Barreiro J, Yin X, Mayr U, Baig F, Lu R, Fava M, Hayward R, Molenaar C, White SJ, Roleder T, Milewski K, Gasior P, ... ... Shanahan C, et al. Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries. Circulation. PMID 29030347 DOI: 10.1161/CIRCULATIONAHA.116.023381 |
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| 2005 |
Zhang Q, Ragnauth CD, Skepper JN, Worth NF, Warren DT, Roberts RG, Weissberg PL, Ellis JA, Shanahan CM. Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle. Journal of Cell Science. 118: 673-87. PMID 15671068 DOI: 10.1242/jcs.01642 |
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| 2005 |
Zhang Q, Ragnauth CD, Skepper JN, Worth NF, Warren DT, Roberts RG, Weissberg PL, Ellis JA, Shanahan CM. Nesprin-2 is a multi-isomeric protein that binds lamin and emerin at the nuclear envelope and forms a subcellular network in skeletal muscle. Journal of Cell Science. 118: 673-87. PMID 15671068 DOI: 10.1242/jcs.01642 |
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| 2013 |
New S, Goettsch C, Aikawa M, Marchini JM, Shanahan C, Croce K, Aikawa E. Inflammation-dependent mechanism of calcification: a new role for macrophage matrix vesicles Cardiovascular Pathology. 22: e46. DOI: 10.1016/J.CARPATH.2013.01.061 |
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| 2000 |
King-Briggs KE, Shanahan CM. TGF-β superfamily members do not promote smooth muscle-specific alternative splicing, a late marker of vascular smooth muscle cell differentiation Differentiation. 66: 43-48. DOI: 10.1046/J.1432-0436.2000.066001043.X |
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| 2017 |
Zhou C, Li C, Zhou B, Sun H, Koullourou V, Holt I, Puckelwartz MJ, Warren DT, Hayward R, Lin Z, Zhang L, Morris GE, McNally EM, Shackleton S, Rao L, ... Shanahan CM, et al. Novel nesprin-1 mutations associated with dilated cardiomyopathy cause nuclear envelope disruption and defects in myogenesis. Human Molecular Genetics. PMID 28398466 DOI: 10.1093/Hmg/Ddx116 |
0.165 |
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| 2024 |
Li C, Warren DT, Zhou C, De Silva S, Wilson DGS, Garcia-Maya M, Wheeler MA, Meinke P, Sawyer G, Ehler E, Wehnert M, Rao L, Zhang Q, Shanahan CM. Nesprin-2 is a novel scaffold protein for telethonin and FHL-2 in the cardiomyocyte sarcomere. The Journal of Biological Chemistry. 107254. PMID 38569934 DOI: 10.1016/j.jbc.2024.107254 |
0.162 |
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| 2010 |
Warren DT, Tajsic T, Mellad JA, Searles R, Zhang Q, Shanahan CM. Novel nuclear nesprin-2 variants tether active extracellular signal-regulated MAPK1 and MAPK2 at promyelocytic leukemia protein nuclear bodies and act to regulate smooth muscle cell proliferation. The Journal of Biological Chemistry. 285: 1311-20. PMID 19861416 DOI: 10.1074/jbc.M109.032557 |
0.162 |
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| 2018 |
Brayson D, Ho CY, Shanahan CM. Muscle tensions merge to cause a DNA replication crisis. The Journal of Cell Biology. PMID 29769233 DOI: 10.1083/jcb.201804041 |
0.162 |
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| 2022 |
Cobb AM, De Silva SA, Hayward R, Sek K, Ulferts S, Grosse R, Shanahan CM. Filamentous nuclear actin regulation of PML NBs during the DNA damage response is deregulated by prelamin A. Cell Death & Disease. 13: 1042. PMID 36522328 DOI: 10.1038/s41419-022-05491-4 |
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| 2016 |
Autore F, Shanahan CM, Zhang Q. Identification and Validation of Putative Nesprin Variants. Methods in Molecular Biology (Clifton, N.J.). 1411: 211-20. PMID 27147044 DOI: 10.1007/978-1-4939-3530-7_13 |
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| 2002 |
Zhang QJ, Goddard M, Shanahan C, Shapiro L, Bennett M. Differential gene expression in vascular smooth muscle cells in primary atherosclerosis and in stent stenosis in humans. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 2030-6. PMID 12482830 DOI: 10.1161/01.ATV.0000042206.98651.15 |
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| 2011 |
Mellad JA, Warren DT, Shanahan CM. Nesprins LINC the nucleus and cytoskeleton. Current Opinion in Cell Biology. 23: 47-54. PMID 21177090 DOI: 10.1016/j.ceb.2010.11.006 |
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| 2016 |
Cobb AM, Murray TV, Warren DT, Liu Y, Shanahan CM. Disruption of PCNA-lamin A interactions by prelamin A induces DNA replication fork stalling. Nucleus (Austin, Tex.). 0. PMID 27676213 DOI: 10.1080/19491034.2016.1239685 |
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| 2008 |
Cunningham J, Floege J, London G, Rodriguez M, Shanahan CM. Clinical outcomes in secondary hyperparathyroidism and the potential role of calcimimetics. Ndt Plus. 1: i29-i35. PMID 25983954 DOI: 10.1093/ndtplus/sfm042 |
0.157 |
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| 2001 |
Farzaneh-Far A, Davies JD, Braam LA, Spronk HM, Proudfoot D, Chan SW, O'Shaughnessy KM, Weissberg PL, Vermeer C, Shanahan CM. A polymorphism of the human matrix gamma-carboxyglutamic acid protein promoter alters binding of an activating protein-1 complex and is associated with altered transcription and serum levels. The Journal of Biological Chemistry. 276: 32466-73. PMID 11425864 DOI: 10.1074/Jbc.M104909200 |
0.156 |
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| 2011 |
Lombardi ML, Jaalouk DE, Shanahan CM, Burke B, Roux KJ, Lammerding J. The interaction between nesprins and sun proteins at the nuclear envelope is critical for force transmission between the nucleus and cytoskeleton. The Journal of Biological Chemistry. 286: 26743-53. PMID 21652697 DOI: 10.1074/Jbc.M111.233700 |
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| 2019 |
Infante E, Stannard A, Board SJ, Rico-Lastres P, Panagaki F, Beedle AEM, Rajan VS, Rostkova E, Lezamiz A, Wang YJ, Breen SG, Shanahan C, Roca-Cusachs P, Garcia-Manyes S. The mechanical stability of proteins regulates their translocation rate into the cell nucleus. Nature Physics. 15: 973-981. PMID 37484710 DOI: 10.1038/s41567-019-0551-3 |
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| 2005 |
Warren DT, Zhang Q, Weissberg PL, Shanahan CM. Nesprins: intracellular scaffolds that maintain cell architecture and coordinate cell function? Expert Reviews in Molecular Medicine. 7: 1-15. PMID 15953398 DOI: 10.1017/S1462399405009294 |
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| 2003 |
Zhang Q, Ragnauth C, Greener MJ, Shanahan CM, Roberts RG. The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300. Genomics. 80: 473-81. PMID 12408964 |
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| 2014 |
Petrova NL, Petrov PK, Edmonds ME, Shanahan CM. Novel use of a Dektak 150 surface profiler unmasks differences in resorption pit profiles between control and Charcot patient osteoclasts. Calcified Tissue International. 94: 403-11. PMID 24322885 DOI: 10.1007/s00223-013-9820-9 |
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| 2011 |
Kapustin AN, Shanahan CM. Osteocalcin: a novel vascular metabolic and osteoinductive factor? Arteriosclerosis, Thrombosis, and Vascular Biology. 31: 2169-71. PMID 21918209 DOI: 10.1161/ATVBAHA.111.233601 |
0.144 |
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| 2020 |
Tsakali SS, Shanahan CM. Calcinosis: insights from other calcinoses. Current Opinion in Rheumatology. 32: 472-478. PMID 32890031 DOI: 10.1097/BOR.0000000000000746 |
0.144 |
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| 2015 |
Chitalia N, Ross L, Krishnamoorthy M, Kapustin A, Shanahan CM, Kaski JC, Roy-Chaudhury P, Chemla E, Banerjee D. Neointimal hyperplasia and calcification in medium sized arteries in adult patients with chronic kidney disease. Seminars in Dialysis. 28: E35-40. PMID 25488635 DOI: 10.1111/sdi.12335 |
0.144 |
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| 2004 |
Goodman WG, London G, Amann K, Block GA, Giachelli C, Hruska KA, Ketteler M, Levin A, Massy Z, McCarron DA, Raggi P, Shanahan CM, Yorioka N. Vascular calcification in chronic kidney disease. American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation. 43: 572-9. PMID 14981617 DOI: 10.1053/J.Ajkd.2003.12.005 |
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| 2012 |
Rajgor D, Mellad JA, Autore F, Zhang Q, Shanahan CM. Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds. Plos One. 7: e40098. PMID 22768332 DOI: 10.1371/journal.pone.0040098 |
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| 2007 |
Ji JY, Lee RT, Vergnes L, Fong LG, Stewart CL, Reue K, Young SG, Zhang Q, Shanahan CM, Lammerding J. Cell nuclei spin in the absence of lamin b1. The Journal of Biological Chemistry. 282: 20015-26. PMID 17488709 DOI: 10.1074/Jbc.M611094200 |
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| 2013 |
Autore F, Pfuhl M, Quan X, Williams A, Roberts RG, Shanahan CM, Fraternali F. Large-scale modelling of the divergent spectrin repeats in nesprins: giant modular proteins. Plos One. 8: e63633. PMID 23671687 DOI: 10.1371/journal.pone.0063633 |
0.137 |
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| 2014 |
Furmanik M, Shanahan CM. 14 The Role of ER Stress in Vascular Calcification Heart. 100: A5.4-A6. DOI: 10.1136/heartjnl-2013-305297.14 |
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| 2015 |
Soon E, Crosby A, Southwood M, Yang P, Tajsic T, Toshner M, Appleby S, Shanahan CM, Bloch KD, Pepke-Zaba J, Upton P, Morrell NW. BMPR-II Deficiency Promotes Pulmonary Hypertension via Increased Inflammatory Cytokine Production. American Journal of Respiratory and Critical Care Medicine. PMID 26073741 DOI: 10.1164/rccm.201408-1509OC |
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| 2014 |
Duong NT, Morris GE, Lam le T, Zhang Q, Sewry CA, Shanahan CM, Holt I. Nesprins: tissue-specific expression of epsilon and other short isoforms. Plos One. 9: e94380. PMID 24718612 DOI: 10.1371/journal.pone.0094380 |
0.131 |
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| 2016 |
Holt I, Duong NT, Zhang Q, Lam le T, Sewry CA, Mamchaoui K, Shanahan CM, Morris GE. Specific localization of nesprin-1-α2, the short isoform of nesprin-1 with a KASH domain, in developing, fetal and regenerating muscle, using a new monoclonal antibody. Bmc Cell Biology. 17: 26. PMID 27350129 DOI: 10.1186/s12860-016-0105-9 |
0.131 |
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| 2017 |
Elosegui-Artola A, Andreu I, Beedle AEM, Lezamiz A, Uroz M, Kosmalska AJ, Oria R, Kechagia JZ, Rico-Lastres P, Le Roux AL, Shanahan CM, Trepat X, Navajas D, Garcia-Manyes S, Roca-Cusachs P. Force Triggers YAP Nuclear Entry by Regulating Transport across Nuclear Pores. Cell. PMID 29107331 DOI: 10.1016/J.Cell.2017.10.008 |
0.13 |
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| 2017 |
Langley SR, Willeit K, Didangelos A, Matic LP, Skroblin P, Barallobre-Barreiro J, Lengquist M, Rungger G, Kapustin A, Kedenko L, Molenaar C, Lu R, Barwari T, Suna G, Yin X, ... ... Shanahan CM, et al. Extracellular matrix proteomics identifies molecular signature of symptomatic carotid plaques. The Journal of Clinical Investigation. PMID 28319050 DOI: 10.1172/JCI86924 |
0.129 |
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| 2016 |
Santos CX, Hafstad AD, Beretta M, Zhang M, Molenaar C, Kopec J, Fotinou D, Murray TV, Cobb AM, Martin D, Zeh Silva M, Anilkumar N, Schröder K, Shanahan CM, Brewer AC, et al. Targeted redox inhibition of protein phosphatase 1 by Nox4 regulates eIF2α-mediated stress signaling. The Embo Journal. PMID 26742780 DOI: 10.15252/Embj.201592394 |
0.129 |
|
| 2019 |
Brayson D, Frustaci A, Verardo R, Chimenti C, Russo MA, Hayward R, Ahmad SM, Vizcay-Barrena G, Protti A, Zammit PS, Dos Remedios CG, Ehler E, Shah AM, Shanahan CM. Prelamin A mediates inflammation in dilated and HIV associated cardiomyopathies. Jci Insight. PMID 31622279 DOI: 10.1172/jci.insight.126315 |
0.126 |
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| 2018 |
Shanahan CM. MOLECULAR AND CELLULAR CHANGES IN ARTERIAL FUNCTION OVER THE LIFE COURSE – FROM ACCELERATED AGEING TO CALCIFICATION Artery Research. 24: 64. DOI: 10.1016/j.artres.2018.10.011 |
0.125 |
|
| 2002 |
Tyson KL, Weissberg PL, Shanahan CM. Heterogeneity of gene expression in human atheroma unmasked using cDNA representational difference analysis Physiological Genomics. 2002: 121-130. PMID 12006678 DOI: 10.1152/PHYSIOLGENOMICS.00116.2001 |
0.124 |
|
| 2013 |
Furmanik M, Shanahan CM. 178 ER STRESS IN VASCULAR CALCIFICATION Heart. 99: A101.3-A102. DOI: 10.1136/heartjnl-2013-304019.178 |
0.119 |
|
| 2012 |
Schurgers LJ, Joosen IA, Laufer EM, Chatrou ML, Herfs M, Winkens MH, Westenfeld R, Veulemans V, Krueger T, Shanahan CM, Jahnen-Dechent W, Biessen E, Narula J, Vermeer C, Hofstra L, et al. Vitamin K-antagonists accelerate atherosclerotic calcification and induce a vulnerable plaque phenotype. Plos One. 7: e43229. PMID 22952653 DOI: 10.1371/Journal.Pone.0043229 |
0.119 |
|
| 2014 |
Rajgor D, Mellad JA, Soong D, Rattner JB, Fritzler MJ, Shanahan CM. Mammalian microtubule P-body dynamics are mediated by nesprin-1. The Journal of Cell Biology. 205: 457-75. PMID 24862572 DOI: 10.1083/Jcb.201306076 |
0.116 |
|
| 2005 |
Burke B, Shanahan C, Salina D, Crisp M. Aspects of nuclear envelope dynamics in mitotic cells. Novartis Foundation Symposium. 264: 22-30; discussion 30. PMID 15773745 |
0.115 |
|
| 2015 |
Petrova NL, Petrov PK, Edmonds ME, Shanahan CM. Inhibition of TNF-α Reverses the Pathological Resorption Pit Profile of Osteoclasts from Patients with Acute Charcot Osteoarthropathy. Journal of Diabetes Research. 2015: 917945. PMID 26137498 DOI: 10.1155/2015/917945 |
0.115 |
|
| 2016 |
Rajgor D, Hanley JG, Shanahan CM. Identification of novel nesprin-1 binding partners and cytoplasmic Matrin-3 in P-bodies. Molecular Biology of the Cell. PMID 27733621 DOI: 10.1091/mbc.E16-06-0346 |
0.112 |
|
| 2019 |
Holt I, Fuller HR, Lam LT, Sewry CA, Shirran SL, Zhang Q, Shanahan CM, Morris GE. Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle. Scientific Reports. 9: 14202. PMID 31578382 DOI: 10.1038/s41598-019-50728-6 |
0.111 |
|
| 2015 |
Kapustin AN, Kalinina N, Lopatina T, Davidson SM, Iraci N, Tamkovich S, Smyth L, Ter-Ovanesyan D, Evtushenko EG, Savelieva O, Bertazzo S, Aushev V, Dragovic R, Gracia T, Heck M, ... ... Shanahan CM, et al. UK-Russia Researcher Links Workshop: extracellular vesicles - mechanisms of biogenesis and roles in disease pathogenesis, M.V. Lomonosov Moscow State University, Moscow, Russia, 1-5 March 2015. Journal of Extracellular Vesicles. 4: 28094. PMID 25979355 DOI: 10.3402/jev.v4.28094 |
0.105 |
|
| 2002 |
Zhang Q, Ragnauth C, Greener MJ, Shanahan CM, Roberts RG. The Nesprins Are Giant Actin-Binding Proteins, Orthologous to Drosophila melanogaster Muscle Protein MSP-300 Genomics. 80: 473-481. DOI: 10.1006/GENO.2002.6859 |
0.099 |
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| 2021 |
Cecelja M, Shanahan CM. Targeting Cell Stiffness: A Paradigm Shift in the Treatment of Aortic Stiffness. Circulation Research. 128: 769-771. PMID 33734817 DOI: 10.1161/CIRCRESAHA.121.318954 |
0.099 |
|
| 2010 |
Haque F, Mazzeo D, Patel JT, Smallwood DT, Ellis JA, Shanahan CM, Shackleton S. Mammalian SUN protein interaction networks at the inner nuclear membrane and their role in laminopathy disease processes. The Journal of Biological Chemistry. 285: 3487-98. PMID 19933576 DOI: 10.1074/jbc.M109.071910 |
0.098 |
|
| 2016 |
Zhang Q, Minaisah RM, Ferraro E, Li C, Porter LJ, Zhou C, Gao F, Zhang J, Rajgor D, Autore F, Shanahan CM, Warren DT. N-terminal nesprin-2 variants regulate β-catenin signalling. Experimental Cell Research. PMID 27321956 DOI: 10.1016/j.yexcr.2016.06.008 |
0.096 |
|
| 2007 |
Shanahan CM. Inflammation ushers in calcification: a cycle of damage and protection? Circulation. 116: 2782-5. PMID 18071088 DOI: 10.1161/CIRCULATIONAHA.107.749655 |
0.093 |
|
| 2000 |
Kennedy JH, Henrion D, Wassef M, Shanahan C, Bloch G, Tedgui A. Osteopontin expression and calcium content in human aortic valves The Journal of Thoracic and Cardiovascular Surgery. 120: 427. DOI: 10.1067/MTC.2000.106968 |
0.091 |
|
| 2001 |
Shanahan CM, Carpenter KL, Cary NR. A potential role for sterol 27-hydroxylase in atherogenesis. Atherosclerosis. 154: 269-76. PMID 11166758 DOI: 10.1016/S0021-9150(00)00473-1 |
0.091 |
|
| 2007 |
Wheeler MA, Davies JD, Zhang Q, Emerson LJ, Hunt J, Shanahan CM, Ellis JA. Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy. Experimental Cell Research. 313: 2845-57. PMID 17462627 DOI: 10.1016/j.yexcr.2007.03.025 |
0.09 |
|
| 2006 |
Haque F, Lloyd DJ, Smallwood DT, Dent CL, Shanahan CM, Fry AM, Trembath RC, Shackleton S. SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton. Molecular and Cellular Biology. 26: 3738-51. PMID 16648470 DOI: 10.1128/MCB.26.10.3738-3751.2006 |
0.088 |
|
| 2014 |
Rajgor D, Shanahan CM. RNA granules and cytoskeletal links. Biochemical Society Transactions. 42: 1206-10. PMID 25110026 DOI: 10.1042/BST20140067 |
0.086 |
|
| 2014 |
Petrova NL, Petrov PK, Edmonds ME, Shanahan CM. Erratum to: Novel Use of a Dektak 150 Surface Profiler Unmasks Differences in Resorption Pit Profiles Between Control and Charcot Patient Osteoclasts Calcified Tissue International. 94: 412-413. DOI: 10.1007/S00223-014-9841-Z |
0.085 |
|
| 2021 |
Sarafidis P, Martens S, Saratzis A, Kadian-Dodov D, Murray PT, Shanahan CM, Hamdan AD, Engelman DT, Teichgräber U, Herzog CA, Cheung M, Jadoul M, Winkelmayer WC, Reinecke H, Johansen K, et al. Diseases of the Aorta and Kidney Disease: Conclusions from a Kidney Disease: Improving Global Outcomes (KDIGO) Controversies Conference. Cardiovascular Research. PMID 34469520 DOI: 10.1093/cvr/cvab287 |
0.084 |
|
| 2020 |
Whitehead M, Shanahan CM. Circulating uromodulin: a cytokine trap for osteoinductive inflammatory mediators in chronic kidney disease? Cardiovascular Research. PMID 33367494 DOI: 10.1093/cvr/cvaa348 |
0.067 |
|
| 2010 |
Prando C, Boisson-Dupuis S, Grant AV, Kong XF, Bustamante J, Feinberg J, Chapgier A, Rose Y, Jannière L, Rizzardi E, Zhang Q, Shanahan CM, Viollet L, Lyonnet S, Abel L, et al. Paternal uniparental isodisomy of chromosome 6 causing a complex syndrome including complete IFN-gamma receptor 1 deficiency. American Journal of Medical Genetics. Part A. 152: 622-9. PMID 20186794 DOI: 10.1002/Ajmg.A.33291 |
0.062 |
|
| 2009 |
Nikolova-Krstevski V, Leimena C, Carlton A, Stewart C, Shanahan C, Fatkin D. Nesprin/actin cytoskeletal network is a critical determinant of cardiac function in lamin A/C deficient mice Heart, Lung and Circulation. 18: S252. DOI: 10.1016/J.HLC.2009.05.622 |
0.057 |
|
| 2020 |
Tsakali SS, Shanahan CM. Calcinosis: insights from other calcinoses Current Opinion in Rheumatology. 32: 472-478. DOI: 10.1097/BOR.0000000000000746 |
0.053 |
|
| 2011 |
Shroff R, Shanahan CM. Klotho: an elixir of youth for the vasculature? Journal of the American Society of Nephrology : Jasn. 22: 5-7. PMID 21164022 DOI: 10.1681/ASN.2010111190 |
0.042 |
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| 2005 |
Khanna A, Li P, Gong Y, Zu N, Li Y, Wang B, Shimizu F, Farzaneh-Far A, Shanahan CM, Armstrong SR, Campbell GR, Campbell JH, Little MH, Chang JW, Kim CS, et al. Contents Vol. 101, 2005 Nephron Experimental Nephrology. 101. DOI: 10.1159/000089539 |
0.04 |
|
| 2015 |
Shanahan CA, Lewis J. Perceptions of interprofessional clinical simulation among medical and nursing students: A pilot study. Journal of Interprofessional Care. 1-3. PMID 26091369 DOI: 10.3109/13561820.2015.1027336 |
0.016 |
|
| 2019 |
Shanahan CM, Shroff R. The authors reply. Kidney International. 96: 523. PMID 31331479 DOI: 10.1016/j.kint.2019.05.020 |
0.01 |
|
| 2012 |
Nanka O, Krejci E, Pesevski Z, Sedmera D, Smart N, Rossdeutsch A, Dube KN, Riegler J, Price AN, Taylor A, Muthurangu V, Turner M, Lythgoe MF, Riley PR, Kryvorot S, ... ... Shanahan CM, et al. Poster session 3 Cardiovascular Research. 93: S92-S127. DOI: 10.1093/Cvr/Cvr336 |
0.01 |
|
| 2005 |
Khanna A, Li P, Gong Y, Zu N, Li Y, Wang B, Shimizu F, Farzaneh-Far A, Shanahan CM, Armstrong SR, Campbell GR, Campbell JH, Little MH, Chang JW, Kim CS, et al. Subject Index Vol. 101, 2005 Nephron Experimental Nephrology. 101. DOI: 10.1159/000089538 |
0.01 |
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