| Year |
Citation |
Score |
| 2024 |
Eggert J, Zinzow-Kramer WM, Hu Y, Kolawole EM, Tsai YL, Weiss A, Evavold BD, Salaita K, Scharer CD, Au-Yeung BB. Cbl-b mitigates the responsiveness of naive CD8 T cells that experience extensive tonic T cell receptor signaling. Science Signaling. 17: eadh0439. PMID 38319998 DOI: 10.1126/scisignal.adh0439 |
0.463 |
|
| 2023 |
Tsai YL, Arias-Badia M, Kadlecek TA, Lwin YM, Srinath A, Shah NH, Wang ZE, Barber D, Kuriyan J, Fong L, Weiss A. TCR signaling promotes formation of an STS1-Cbl-b complex with pH-sensitive phosphatase activity that suppresses T cell function in acidic environments. Immunity. 56: 2682-2698.e9. PMID 38091950 DOI: 10.1016/j.immuni.2023.11.010 |
0.71 |
|
| 2023 |
Weiss A. Peeking Into the Black Box of T Cell Receptor Signaling. Annual Review of Immunology. PMID 37788477 DOI: 10.1146/annurev-immunol-090222-112028 |
0.412 |
|
| 2023 |
Nguyen TTT, Lu W, Zhu WS, Ansel KM, Liang HE, Weiss A. Stimulation of ectopically expressed muscarinic receptors induces IFN-γ but suppresses IL-2 production by inhibiting activation of pAKT pathways in primary T cells. Proceedings of the National Academy of Sciences of the United States of America. 120: e2300987120. PMID 37307442 DOI: 10.1073/pnas.2300987120 |
0.407 |
|
| 2023 |
Lo WL, Kuhlmann M, Rizzuto G, Ekiz HA, Kolawole EM, Revelo MP, Andargachew R, Li Z, Tsai YL, Marson A, Evavold BD, Zehn D, Weiss A. A single-amino acid substitution in the adaptor LAT accelerates TCR proofreading kinetics and alters T-cell selection, maintenance and function. Nature Immunology. PMID 36914891 DOI: 10.1038/s41590-023-01444-x |
0.398 |
|
| 2023 |
Eggert J, Zinzow-Kramer WM, Hu Y, Tsai YL, Weiss A, Salaita K, Scharer CD, Au-Yeung BB. Accumulation of TCR signaling from self-antigens in naive CD8 T cells mitigates early responsiveness. Biorxiv : the Preprint Server For Biology. PMID 36747815 DOI: 10.1101/2023.01.27.525946 |
0.443 |
|
| 2022 |
Lu W, Helou YA, Shrinivas K, Liou J, Au-Yeung BB, Weiss A. The phosphatidylinositol-transfer protein Nir3 promotes PI(4,5)P replenishment in response to TCR signaling during T cell development and survival. Nature Immunology. 24: 136-147. PMID 36581712 DOI: 10.1038/s41590-022-01372-2 |
0.662 |
|
| 2022 |
Horkova V, Drobek A, Paprckova D, Niederlova V, Prasai A, Uleri V, Glatzova D, Kraller M, Cesnekova M, Janusova S, Salyova E, Tsyklauri O, Kadlecek TA, Krizova K, Platzer R, ... ... Weiss A, et al. Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature Immunology. 24: 174-185. PMID 36564464 DOI: 10.1038/s41590-022-01366-0 |
0.445 |
|
| 2021 |
Ashouri JF, Lo WL, Nguyen TTT, Shen L, Weiss A. ZAP70, too little, too much can lead to autoimmunity. Immunological Reviews. PMID 34923645 DOI: 10.1111/imr.13058 |
0.388 |
|
| 2021 |
Huang F, Nguyen TT, Echeverria I, Ramachandran R, Cary DC, Paculova H, Sali A, Weiss A, Peterlin BM, Fujinaga K. Reversible phosphorylation of cyclin T1 promotes assembly and stability of P-TEFb. Elife. 10. PMID 34821217 DOI: 10.7554/eLife.68473 |
0.362 |
|
| 2021 |
Lu W, Skrzypczynska KM, Weiss A. Acute Csk inhibition hinders B cell activation by constraining the PI3 kinase pathway. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 34675079 DOI: 10.1073/pnas.2108957118 |
0.5 |
|
| 2021 |
Nguyen TTT, Wang ZE, Shen L, Schroeder A, Eckalbar W, Weiss A. Cbl-b deficiency prevents functional but not phenotypic T cell anergy. The Journal of Experimental Medicine. 218. PMID 33974042 DOI: 10.1084/jem.20202477 |
0.403 |
|
| 2021 |
Lo WL, Weiss A. Adapting T Cell Receptor Ligand Discrimination Capability LAT. Frontiers in Immunology. 12: 673196. PMID 33936119 DOI: 10.3389/fimmu.2021.673196 |
0.4 |
|
| 2021 |
Hallumi E, Shalah R, Lo WL, Corso J, Oz I, Beach D, Wittman S, Isenberg A, Sela M, Urlaub H, Weiss A, Yablonski D. Itk Promotes the Integration of TCR and CD28 Costimulation through Its Direct Substrates SLP-76 and Gads. Journal of Immunology (Baltimore, Md. : 1950). PMID 33931484 DOI: 10.4049/jimmunol.2001053 |
0.44 |
|
| 2021 |
Shen L, Matloubian M, Kadlecek TA, Weiss A. A disease-associated mutation that weakens ZAP70 autoinhibition enhances responses to weak and self-ligands. Science Signaling. 14. PMID 33531381 DOI: 10.1126/scisignal.abc4479 |
0.344 |
|
| 2020 |
Ganti RS, Lo WL, McAffee DB, Groves JT, Weiss A, Chakraborty AK. How the T cell signaling network processes information to discriminate between self and agonist ligands. Proceedings of the National Academy of Sciences of the United States of America. PMID 33020303 DOI: 10.1073/pnas.2008303117 |
0.324 |
|
| 2020 |
Nocka LM, Chung JK, Decker A, Kadlecek T, Weiss A, Kuriyan J, Groves JT. Bruton's Tyrosine Kinase Membrane Dynamics and Signaling Biophysical Journal. 118: 560a-561a. DOI: 10.1016/J.Bpj.2019.11.3060 |
0.684 |
|
| 2020 |
Ganti RS, Lo W, McAffee D, Groves JT, Weiss A, Chakraborty AK. How the T Cell Signaling Network Processes Information to Discriminate between Self and Cognate Ligands Biophysical Journal. 118: 245a. DOI: 10.1016/J.Bpj.2019.11.1436 |
0.367 |
|
| 2019 |
Courtney AH, Shvets AA, Lu W, Griffante G, Mollenauer M, Horkova V, Lo WL, Yu S, Stepanek O, Chakraborty AK, Weiss A. CD45 functions as a signaling gatekeeper in T cells. Science Signaling. 12. PMID 31641081 DOI: 10.1126/Scisignal.Aaw8151 |
0.524 |
|
| 2019 |
Lo WL, Shah NH, Rubin SA, Zhang W, Horkova V, Fallahee IR, Stepanek O, Zon LI, Kuriyan J, Weiss A. Slow phosphorylation of a tyrosine residue in LAT optimizes T cell ligand discrimination. Nature Immunology. PMID 31611699 DOI: 10.1038/S41590-019-0502-2 |
0.759 |
|
| 2019 |
Shang W, Jiang Y, Weiss A, Wang W. Explore new cancer immunotherapy targets in T cell signaling pathway using proteomic and genetic approaches European Journal of Immunology. 49. PMID 31592543 DOI: 10.1002/Eji.201970400 |
0.388 |
|
| 2019 |
Ashouri JF, Hsu LY, Yu S, Rychkov D, Chen Y, Cheng DA, Sirota M, Hansen E, Lattanza L, Zikherman J, Weiss A. Reporters of TCR signaling identify arthritogenic T cells in murine and human autoimmune arthritis. Proceedings of the National Academy of Sciences of the United States of America. PMID 31455730 DOI: 10.1073/Pnas.1904271116 |
0.493 |
|
| 2019 |
Zinzow-Kramer WM, Weiss A, Au-Yeung BB. Adaptation by naïve CD4 T cells to self-antigen-dependent TCR signaling induces functional heterogeneity and tolerance. Proceedings of the National Academy of Sciences of the United States of America. PMID 31285342 DOI: 10.1073/Pnas.1904096116 |
0.49 |
|
| 2019 |
Chung JK, Nocka LM, Decker A, Wang Q, Kadlecek TA, Weiss A, Kuriyan J, Groves JT. Switch-like activation of Bruton's tyrosine kinase by membrane-mediated dimerization. Proceedings of the National Academy of Sciences of the United States of America. PMID 31076553 DOI: 10.1073/Pnas.1819309116 |
0.71 |
|
| 2019 |
Wang Y, Huynh W, Skokan TD, Lu W, Weiss A, Vale RD. CRACR2a is a calcium-activated dynein adaptor protein that regulates endocytic traffic. The Journal of Cell Biology. PMID 30814157 DOI: 10.1083/Jcb.201806097 |
0.386 |
|
| 2018 |
Lo WL, Shah NH, Ahsan N, Horkova V, Stepanek O, Salomon AR, Kuriyan J, Weiss A. Lck promotes Zap70-dependent LAT phosphorylation by bridging Zap70 to LAT. Nature Immunology. PMID 29915297 DOI: 10.1038/S41590-018-0131-1 |
0.771 |
|
| 2018 |
Shang W, Jiang Y, Boettcher M, Ding K, Mollenauer M, Liu Z, Wen X, Liu C, Hao P, Zhao S, McManus MT, Wei L, Weiss A, Wang H. Genome-wide CRISPR screen identifies FAM49B as a key regulator of actin dynamics and T cell activation. Proceedings of the National Academy of Sciences of the United States of America. PMID 29632189 DOI: 10.1073/Pnas.1801340115 |
0.7 |
|
| 2018 |
Shah NH, Löbel M, Weiss A, Kuriyan J. Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen. Elife. 7. PMID 29547119 DOI: 10.7554/Elife.35190 |
0.74 |
|
| 2018 |
Mori J, Nagy Z, Di Nunzio G, Smith CW, Geer MJ, Al Ghaithi R, van Geffen JP, Heising S, Boothman L, Tullemans BME, Correia JN, Tee L, Kuijpers MJE, Harrison P, Heemskerk JWM, ... ... Weiss A, et al. Maintenance of murine platelet homeostasis by the kinase Csk and the phosphatase CD148. Blood. PMID 29301754 DOI: 10.1182/Blood-2017-02-768077 |
0.501 |
|
| 2018 |
Shah NH, Löbel M, Weiss A, Kuriyan J. Author response: Fine-tuning of substrate preferences of the Src-family kinase Lck revealed through a high-throughput specificity screen Elife. DOI: 10.7554/Elife.35190.025 |
0.663 |
|
| 2017 |
Courtney AH, Lo WL, Weiss A. TCR Signaling: Mechanisms of Initiation and Propagation. Trends in Biochemical Sciences. PMID 29269020 DOI: 10.1016/j.tibs.2017.11.008 |
0.397 |
|
| 2017 |
Courtney AH, Lo WL, Weiss A. TCR Signaling: Mechanisms of Initiation and Propagation. Trends in Biochemical Sciences. PMID 29269020 DOI: 10.1016/J.Tibs.2017.11.008 |
0.497 |
|
| 2017 |
Courtney AH, Lo WL, Weiss A. TCR Signaling: Mechanisms of Initiation and Propagation. Trends in Biochemical Sciences. PMID 29269020 DOI: 10.1016/j.tibs.2017.11.008 |
0.397 |
|
| 2017 |
Courtney AH, Lo WL, Weiss A. TCR Signaling: Mechanisms of Initiation and Propagation. Trends in Biochemical Sciences. PMID 29269020 DOI: 10.1016/j.tibs.2017.11.008 |
0.397 |
|
| 2017 |
Smith GA, Taunton J, Weiss A. IL-2Rβ abundance differentially tunes IL-2 signaling dynamics in CD4+ and CD8+ T cells. Science Signaling. 10. PMID 29259099 DOI: 10.1126/Scisignal.Aan4931 |
0.733 |
|
| 2017 |
Au-Yeung BB, Shah NH, Shen L, Weiss A. ZAP-70 in Signaling, Biology, and Disease. Annual Review of Immunology. PMID 29237129 DOI: 10.1146/Annurev-Immunol-042617-053335 |
0.464 |
|
| 2017 |
Au-Yeung BB, Shah NH, Shen L, Weiss A. ZAP-70 in Signaling, Biology, and Disease. Annual Review of Immunology. PMID 29237129 DOI: 10.1146/Annurev-Immunol-042617-053335 |
0.464 |
|
| 2017 |
Au-Yeung BB, Shah NH, Shen L, Weiss A. ZAP-70 in Signaling, Biology, and Disease. Annual Review of Immunology. PMID 29237129 DOI: 10.1146/Annurev-Immunol-042617-053335 |
0.464 |
|
| 2017 |
Au-Yeung BB, Shah NH, Shen L, Weiss A. ZAP-70 in Signaling, Biology, and Disease. Annual Review of Immunology. PMID 29237129 DOI: 10.1146/Annurev-Immunol-042617-053335 |
0.464 |
|
| 2017 |
Courtney AH, Amacher JF, Kadlecek TA, Mollenauer MN, Au-Yeung BB, Kuriyan J, Weiss A. A Phosphosite within the SH2 Domain of Lck Regulates Its Activation by CD45. Molecular Cell. PMID 28735895 DOI: 10.1016/J.Molcel.2017.06.024 |
0.784 |
|
| 2017 |
Au-Yeung BB, Smith GA, Mueller JL, Heyn CS, Jaszczak RG, Weiss A, Zikherman J. IL-2 Modulates the TCR Signaling Threshold for CD8 but Not CD4 T Cell Proliferation on a Single-Cell Level. Journal of Immunology (Baltimore, Md. : 1950). PMID 28159902 DOI: 10.4049/Jimmunol.1601453 |
0.675 |
|
| 2017 |
Hsu LY, Cheng DA, Chen Y, Liang HE, Weiss A. Destabilizing the autoinhibitory conformation of Zap70 induces up-regulation of inhibitory receptors and T cell unresponsiveness. The Journal of Experimental Medicine. PMID 28159798 DOI: 10.1084/Jem.20161575 |
0.521 |
|
| 2016 |
Ashouri JF, Weiss A. Endogenous Nur77 Is a Specific Indicator of Antigen Receptor Signaling in Human T and B Cells. Journal of Immunology (Baltimore, Md. : 1950). PMID 27940659 DOI: 10.4049/Jimmunol.1601301 |
0.513 |
|
| 2016 |
Visperas PR, Wilson CG, Winger JA, Yan Q, Lin K, Arkin MR, Weiss A, Kuriyan J. Identification of Inhibitors of the Association of ZAP-70 with the T Cell Receptor by High-Throughput Screen. Journal of Biomolecular Screening. PMID 27932698 DOI: 10.1177/1087057116681407 |
0.82 |
|
| 2016 |
Skrzypczynska KM, Zhu JW, Weiss A. Positive Regulation of Lyn Kinase by CD148 Is Required for B Cell Receptor Signaling in B1 but Not B2 B Cells. Immunity. PMID 27889108 DOI: 10.1016/J.Immuni.2016.10.013 |
0.448 |
|
| 2016 |
Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J. An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor. Elife. 5. PMID 27700984 DOI: 10.7554/Elife.20105 |
0.777 |
|
| 2016 |
Thill PA, Weiss AW, Chakraborty AK. Phosphorylation of a Tyrosine residue on Zap70 by Lck and its subsequent binding via a SH2 domain may be a key gatekeeper of T cell receptor signaling in vivo. Molecular and Cellular Biology. PMID 27354065 DOI: 10.1128/Mcb.00165-16 |
0.455 |
|
| 2016 |
Weiss A. Human LAT mutation results in immune deficiency and autoimmunity but also raises questions about signaling pathways. The Journal of Experimental Medicine. 213: 1114. PMID 27353087 DOI: 10.1084/Jem.2137Insight1 |
0.32 |
|
| 2016 |
Esensten JH, Helou YA, Chopra G, Weiss A, Bluestone JA. CD28 Costimulation: From Mechanism to Therapy. Immunity. 44: 973-88. PMID 27192564 DOI: 10.1016/J.Immuni.2016.04.020 |
0.448 |
|
| 2016 |
Chi S, Weiss A, Wang H. A CRISPR-Based Toolbox for Studying T Cell Signal Transduction. Biomed Research International. 2016: 5052369. PMID 27057542 DOI: 10.1155/2016/5052369 |
0.448 |
|
| 2016 |
Smith GA, Uchida K, Weiss A, Taunton J. Essential biphasic role for JAK3 catalytic activity in IL-2 receptor signaling. Nature Chemical Biology. PMID 27018889 DOI: 10.1038/Nchembio.2056 |
0.772 |
|
| 2016 |
Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, ... ... Weiss A, et al. Corrigendum: Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. PMID 26958840 DOI: 10.1038/Nature16997 |
0.516 |
|
| 2016 |
Chan AY, Punwani D, Kadlecek TA, Cowan MJ, Olson JL, Mathes EF, Sunderam U, Man Fu S, Srinivasan R, Kuriyan J, Brenner SE, Weiss A, Puck JM. A novel human autoimmune syndrome caused by combined hypomorphic and activating mutations in ZAP-70. The Journal of Experimental Medicine. PMID 26783323 DOI: 10.1084/Jem.20150888 |
0.69 |
|
| 2016 |
Shah NH, Wang Q, Yan Q, Karandur D, Kadlecek TA, Fallahee IR, Russ WP, Ranganathan R, Weiss A, Kuriyan J. Author response: An electrostatic selection mechanism controls sequential kinase signaling downstream of the T cell receptor Elife. DOI: 10.7554/Elife.20105.045 |
0.764 |
|
| 2016 |
Courtney AH, Sjolin-Goodfellow HE, Ji Q, Kadlecek TA, Salomon AR, Weiss A. Abstract B042: Regulation of Lck activity by a cryptic phosphosite Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-B042 |
0.6 |
|
| 2016 |
Courtney AH, Kadlecek TA, Au-Yeung B, Weiss A. Abstract A074: A Zap70-dependent negative feedback loop governs Lck activation by CD45 Cancer Immunology Research. 4. DOI: 10.1158/2326-6066.Imm2016-A074 |
0.549 |
|
| 2016 |
Chi S, Weiss A, Wang H. A CRISPR-Based Toolbox for Studying T Cell Signal Transduction Biomed Research International. 2016. DOI: 10.1155/2016/5052369 |
0.384 |
|
| 2015 |
Coughlin S, Noviski M, Mueller JL, Chuwonpad A, Raschke WC, Weiss A, Zikherman J. An extracatalytic function of CD45 in B cells is mediated by CD22. Proceedings of the National Academy of Sciences of the United States of America. PMID 26561584 DOI: 10.1073/Pnas.1519925112 |
0.492 |
|
| 2015 |
Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. LynA regulates an inflammation-sensitive signaling checkpoint in macrophages. Elife. 4. PMID 26517880 DOI: 10.7554/Elife.09183 |
0.815 |
|
| 2015 |
Manz BN, Tan YX, Courtney AH, Rutaganira F, Palmer E, Shokat KM, Weiss A. Small molecule inhibition of Csk alters affinity recognition by T cells. Elife. 4. PMID 26302204 DOI: 10.7554/Elife.08088 |
0.678 |
|
| 2015 |
Sjölin-Goodfellow H, Frushicheva MP, Ji Q, Cheng DA, Kadlecek TA, Cantor AJ, Kuriyan J, Chakraborty AK, Salomon AR, Weiss A. The catalytic activity of the kinase ZAP-70 mediates basal signaling and negative feedback of the T cell receptor pathway. Science Signaling. 8: ra49. PMID 25990959 DOI: 10.1126/Scisignal.2005596 |
0.798 |
|
| 2015 |
Weiss A, Stobo JD. Commentary: "The Role of T3 Surface Molecules in the Activation of Human Cells: A Two-Stimulus Requirement for IL-2 Production Reflects Events Occurring at a Pretranslational Level". Frontiers in Immunology. 6: 163. PMID 25954271 DOI: 10.3389/Fimmu.2015.00163 |
0.467 |
|
| 2015 |
Weiss AC, Kispert A. Eph/ephrin signaling in the kidney and lower urinary tract. Pediatric Nephrology (Berlin, Germany). PMID 25903642 DOI: 10.1007/s00467-015-3112-8 |
0.301 |
|
| 2015 |
Tian R, Wang H, Gish GD, Petsalaki E, Pasculescu A, Shi Y, Mollenauer M, Bagshaw RD, Yosef N, Hunter T, Gingras AC, Weiss A, Pawson T. Combinatorial proteomic analysis of intercellular signaling applied to the CD28 T-cell costimulatory receptor. Proceedings of the National Academy of Sciences of the United States of America. 112: E1594-603. PMID 25829543 DOI: 10.1073/Pnas.1503286112 |
0.494 |
|
| 2015 |
Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Titz B, Graeber TG, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Willman CL, Melnick A, ... ... Weiss A, et al. Signalling thresholds and negative B-cell selection in acute lymphoblastic leukaemia. Nature. 521: 357-61. PMID 25799995 DOI: 10.1038/Nature14231 |
0.618 |
|
| 2015 |
Mills RE, Lam VC, Tan A, Cresalia N, Oksenberg N, Zikherman J, Anderson M, Weiss A, Hermiston ML. Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production. Journal of Immunology (Baltimore, Md. : 1950). 194: 3675-86. PMID 25769918 DOI: 10.4049/Jimmunol.1500026 |
0.346 |
|
| 2015 |
Punwani D, Wang H, Chan AY, Cowan MJ, Mallott J, Sunderam U, Mollenauer M, Srinivasan R, Brenner SE, Mulder A, Claas FH, Weiss A, Puck JM. Combined immunodeficiency due to MALT1 mutations, treated by hematopoietic cell transplantation. Journal of Clinical Immunology. 35: 135-46. PMID 25627829 DOI: 10.1007/S10875-014-0125-1 |
0.359 |
|
| 2015 |
Visperas PR, Winger JA, Horton TM, Shah NH, Aum DJ, Tao A, Barros T, Yan Q, Wilson CG, Arkin MR, Weiss A, Kuriyan J. Modification by covalent reaction or oxidation of cysteine residues in the tandem-SH2 domains of ZAP-70 and Syk can block phosphopeptide binding. The Biochemical Journal. 465: 149-61. PMID 25287889 DOI: 10.1042/Bj20140793 |
0.819 |
|
| 2015 |
Freedman TS, Tan YX, Skrzypczynska KM, Manz BN, Sjaastad FV, Goodridge HS, Lowell CA, Weiss A. Author response: LynA regulates an inflammation-sensitive signaling checkpoint in macrophages Elife. DOI: 10.7554/Elife.09183.029 |
0.765 |
|
| 2015 |
Manz BN, Tan YX, Courtney AH, Rutaganira F, Palmer E, Shokat KM, Weiss A. Author response: Small molecule inhibition of Csk alters affinity recognition by T cells Elife. DOI: 10.7554/Elife.08088.012 |
0.544 |
|
| 2015 |
Chen Z, Geng H, Lowell CA, Weiss A, Hunger SP, Melnick A, Muschen M. Targeted Activation of B Cell Autoimmunity Checkpoints in Acute Lymphoblastic Leukemia Blood. 126: 3716-3716. DOI: 10.1182/Blood.V126.23.3716.3716 |
0.493 |
|
| 2015 |
Chen Z, Shojaee S, Buchner M, Geng H, Lee JW, Klemm L, Park E, Tan YX, Satterthwaite A, Paietta E, Hunger SP, Loh ML, Jung JU, Coligan JE, Bolland S, ... ... Weiss A, et al. Abstract 2075: Signaling thresholds and negative B cell selection in acute lymphoblastic leukemia Cancer Research. 75: 2075-2075. DOI: 10.1158/1538-7445.Am2015-2075 |
0.624 |
|
| 2014 |
Imboden JB, Weiss A, Stobo JD. Transmembrane signalling by the T3-antigen receptor complex. Immunology Today. 6: 328-31. PMID 25291003 DOI: 10.1016/0167-5699(85)90129-X |
0.469 |
|
| 2014 |
Chakraborty AK, Weiss A. Insights into the initiation of TCR signaling. Nature Immunology. 15: 798-807. PMID 25137454 DOI: 10.1038/Ni.2940 |
0.505 |
|
| 2014 |
Au-Yeung BB, Zikherman J, Mueller JL, Ashouri JF, Matloubian M, Cheng DA, Chen Y, Shokat KM, Weiss A. A sharp T-cell antigen receptor signaling threshold for T-cell proliferation. Proceedings of the National Academy of Sciences of the United States of America. 111: E3679-88. PMID 25136127 DOI: 10.1073/Pnas.1413726111 |
0.573 |
|
| 2014 |
Schim van der Loeff I, Hsu LY, Saini M, Weiss A, Seddon B. Zap70 is essential for long-term survival of naive CD8 T cells. Journal of Immunology (Baltimore, Md. : 1950). 193: 2873-80. PMID 25092893 DOI: 10.4049/Jimmunol.1400858 |
0.497 |
|
| 2014 |
Ross JO, Melichar HJ, Au-Yeung BB, Herzmark P, Weiss A, Robey EA. Distinct phases in the positive selection of CD8+ T cells distinguished by intrathymic migration and T-cell receptor signaling patterns. Proceedings of the National Academy of Sciences of the United States of America. 111: E2550-8. PMID 24927565 DOI: 10.1073/Pnas.1408482111 |
0.455 |
|
| 2014 |
Au-Yeung BB, Melichar HJ, Ross JO, Cheng DA, Zikherman J, Shokat KM, Robey EA, Weiss A. Quantitative and temporal requirements revealed for Zap70 catalytic activity during T cell development. Nature Immunology. 15: 687-94. PMID 24908390 DOI: 10.1038/Ni.2918 |
0.476 |
|
| 2014 |
Phee H, Au-Yeung BB, Pryshchep O, O'Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A. Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation. Elife. 3: e02270. PMID 24843022 DOI: 10.7554/Elife.02270 |
0.503 |
|
| 2014 |
Wang H, Flach H, Onizawa M, Wei L, McManus MT, Weiss A. Negative regulation of Hif1a expression and TH17 differentiation by the hypoxia-regulated microRNA miR-210. Nature Immunology. 15: 393-401. PMID 24608041 DOI: 10.1038/Ni.2846 |
0.544 |
|
| 2014 |
Jenkins MR, Stinchcombe JC, Au-Yeung BB, Asano Y, Ritter AT, Weiss A, Griffiths GM. Distinct structural and catalytic roles for Zap70 in formation of the immunological synapse in CTL. Elife. 3: e01310. PMID 24596147 DOI: 10.7554/Elife.01310 |
0.389 |
|
| 2014 |
Limnander A, Zikherman J, Lau T, Leitges M, Weiss A, Roose JP. Protein kinase Cδ promotes transitional B cell-negative selection and limits proximal B cell receptor signaling to enforce tolerance. Molecular and Cellular Biology. 34: 1474-85. PMID 24515435 DOI: 10.1128/Mcb.01699-13 |
0.489 |
|
| 2014 |
Tan YX, Manz BN, Freedman TS, Zhang C, Shokat KM, Weiss A. Inhibition of the kinase Csk in thymocytes reveals a requirement for actin remodeling in the initiation of full TCR signaling. Nature Immunology. 15: 186-94. PMID 24317039 DOI: 10.1038/Ni.2772 |
0.854 |
|
| 2014 |
Phee H, Au-Yeung BB, Pryshchep O, O'Hagan KL, Fairbairn SG, Radu M, Kosoff R, Mollenauer M, Cheng D, Chernoff J, Weiss A. Author response: Pak2 is required for actin cytoskeleton remodeling, TCR signaling, and normal thymocyte development and maturation Elife. DOI: 10.7554/Elife.02270.017 |
0.361 |
|
| 2014 |
Melichar H, Au-Yeung B, Ross J, Weiss A, Robey E. Declined Presentation: A T cell receptor signal threshold determines positive selection Experimental Hematology. 42. DOI: 10.1016/J.Exphem.2014.07.183 |
0.482 |
|
| 2014 |
Frushicheva MP, Weiss A, Chakraborty AK. Investigation of Novel Zap-70 Functionality in T Cell Signaling Pathways using Computational Modeling Biophysical Journal. 106: 376a-377a. DOI: 10.1016/J.Bpj.2013.11.2131 |
0.511 |
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| 2013 |
Weiss A. Tony Pawson: Modular protein domains and the links to intracellular signaling. Proceedings of the National Academy of Sciences of the United States of America. 110: 17604-5. PMID 24135003 DOI: 10.1073/Pnas.1317096110 |
0.364 |
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| 2013 |
Tan YX, Zikherman J, Weiss A. Novel tools to dissect the dynamic regulation of TCR signaling by the kinase Csk and the phosphatase CD45. Cold Spring Harbor Symposia On Quantitative Biology. 78: 131-9. PMID 24100586 DOI: 10.1101/Sqb.2013.78.020347 |
0.687 |
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| 2013 |
Gardner JM, Metzger TC, McMahon EJ, Au-Yeung BB, Krawisz AK, Lu W, Price JD, Johannes KP, Satpathy AT, Murphy KM, Tarbell KV, Weiss A, Anderson MS. Extrathymic Aire-expressing cells are a distinct bone marrow-derived population that induce functional inactivation of CD4⁺ T cells. Immunity. 39: 560-72. PMID 23993652 DOI: 10.1016/J.Immuni.2013.08.005 |
0.454 |
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| 2013 |
Katsumoto TR, Kudo M, Chen C, Sundaram A, Callahan EC, Zhu JW, Lin J, Rosen CE, Manz BN, Lee JW, Matthay MA, Huang X, Sheppard D, Weiss A. The phosphatase CD148 promotes airway hyperresponsiveness through SRC family kinases. The Journal of Clinical Investigation. 123: 2037-48. PMID 23543053 DOI: 10.1172/Jci66397 |
0.593 |
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| 2013 |
Yan Q, Barros T, Visperas PR, Deindl S, Kadlecek TA, Weiss A, Kuriyan J. Structural basis for activation of ZAP-70 by phosphorylation of the SH2-kinase linker. Molecular and Cellular Biology. 33: 2188-201. PMID 23530057 DOI: 10.1128/Mcb.01637-12 |
0.806 |
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| 2013 |
Zikherman J, Parameswaran R, Hermiston M, Weiss A. The structural wedge domain of the receptor-like tyrosine phosphatase CD45 enforces B cell tolerance by regulating substrate specificity. Journal of Immunology (Baltimore, Md. : 1950). 190: 2527-35. PMID 23396948 DOI: 10.4049/Jimmunol.1202928 |
0.487 |
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| 2013 |
Mukherjee S, Zhu J, Zikherman J, Parameswaran R, Kadlecek TA, Wang Q, Au-Yeung B, Ploegh H, Kuriyan J, Das J, Weiss A. Monovalent and multivalent ligation of the B cell receptor exhibit differential dependence upon Syk and Src family kinases Science Signaling. 6. PMID 23281368 DOI: 10.1126/Scisignal.2003220 |
0.755 |
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| 2013 |
Weiss A, Das J, VanHook AM. Science Signaling Podcast: 1 January 2013 Science Signaling. 6. DOI: 10.1126/Scisignal.2003867 |
0.48 |
|
| 2012 |
Charles JF, Hsu LY, Niemi EC, Weiss A, Aliprantis AO, Nakamura MC. Inflammatory arthritis increases mouse osteoclast precursors with myeloid suppressor function. The Journal of Clinical Investigation. 122: 4592-605. PMID 23114597 DOI: 10.1172/Jci60920 |
0.357 |
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| 2012 |
Zikherman J, Parameswaran R, Weiss A. Endogenous antigen tunes the responsiveness of naive B cells but not T cells. Nature. 489: 160-4. PMID 22902503 DOI: 10.1038/Nature11311 |
0.453 |
|
| 2012 |
Wei P, Wong WW, Park JS, Corcoran EE, Peisajovich SG, Onuffer JJ, Weiss A, Lim WA. Bacterial virulence proteins as tools to rewire kinase pathways in yeast and immune cells. Nature. 488: 384-8. PMID 22820255 DOI: 10.1038/Nature11259 |
0.493 |
|
| 2012 |
Park CY, Jeker LT, Carver-Moore K, Oh A, Liu HJ, Cameron R, Richards H, Li Z, Adler D, Yoshinaga Y, Martinez M, Nefadov M, Abbas AK, Weiss A, Lanier LL, et al. A resource for the conditional ablation of microRNAs in the mouse. Cell Reports. 1: 385-91. PMID 22570807 DOI: 10.1016/J.Celrep.2012.02.008 |
0.498 |
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| 2012 |
Abel SM, Roose JP, Groves JT, Weiss A, Chakraborty AK. The membrane environment can promote or suppress bistability in cell signaling networks. The Journal of Physical Chemistry. B. 116: 3630-40. PMID 22332778 DOI: 10.1021/Jp2102385 |
0.325 |
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| 2012 |
Baldari CT, Acuto O, Batista F, Koretzky G, Weiss A. Lymphocyte signaling: a Tuscan affair. Nature Immunology. 13: 3-6. PMID 22179269 DOI: 10.1038/Ni.2185 |
0.303 |
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| 2012 |
Zikherman J, Doan K, Parameswaran R, Raschke W, Weiss A. Quantitative differences in CD45 expression unmask functions for CD45 in B-cell development, tolerance, and survival. Proceedings of the National Academy of Sciences of the United States of America. 109: E3-12. PMID 22135465 DOI: 10.1073/Pnas.1117374108 |
0.47 |
|
| 2011 |
Limnander A, Weiss A. Ca-dependent Ras/Erk signaling mediates negative selection of autoreactive B cells. Small Gtpases. 2: 282-288. PMID 22292132 DOI: 10.4161/Sgtp.2.5.17794 |
0.402 |
|
| 2011 |
Zikherman J, Weiss A. Unraveling the functional implications of GWAS: how T cell protein tyrosine phosphatase drives autoimmune disease. The Journal of Clinical Investigation. 121: 4618-21. PMID 22080861 DOI: 10.1172/Jci60001 |
0.444 |
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| 2011 |
Zhu JW, Doan K, Park J, Chau AH, Zhang H, Lowell CA, Weiss A. Receptor-like tyrosine phosphatases CD45 and CD148 have distinct functions in chemoattractant-mediated neutrophil migration and response to S. aureus. Immunity. 35: 757-69. PMID 22078799 DOI: 10.1016/J.Immuni.2011.09.011 |
0.5 |
|
| 2011 |
Markegard E, Trager E, Yang CW, Zhang W, Weiss A, Roose JP. Basal LAT-diacylglycerol-RasGRP1 signals in T cells maintain TCRα gene expression. Plos One. 6: e25540. PMID 21966541 DOI: 10.1371/Journal.Pone.0025540 |
0.516 |
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| 2011 |
Draber P, Vonkova I, Stepanek O, Hrdinka M, Kucova M, Skopcova T, Otahal P, Angelisova P, Horejsi V, Yeung M, Weiss A, Brdicka T. SCIMP, a transmembrane adaptor protein involved in major histocompatibility complex class II signaling. Molecular and Cellular Biology. 31: 4550-62. PMID 21930792 DOI: 10.1128/Mcb.05817-11 |
0.535 |
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| 2011 |
Schoenborn JR, Tan YX, Zhang C, Shokat KM, Weiss A. Feedback circuits monitor and adjust basal Lck-dependent events in T cell receptor signaling. Science Signaling. 4: ra59. PMID 21917715 DOI: 10.1126/Scisignal.2001893 |
0.676 |
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| 2011 |
Stepanek O, Kalina T, Draber P, Skopcova T, Svojgr K, Angelisova P, Horejsi V, Weiss A, Brdicka T. Regulation of Src family kinases involved in T cell receptor signaling by protein-tyrosine phosphatase CD148. The Journal of Biological Chemistry. 286: 22101-12. PMID 21543337 DOI: 10.1074/Jbc.M110.196733 |
0.511 |
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| 2011 |
Goodridge HS, Reyes CN, Becker CA, Katsumoto TR, Ma J, Wolf AJ, Bose N, Chan AS, Magee AS, Danielson ME, Weiss A, Vasilakos JP, Underhill DM. Activation of the innate immune receptor Dectin-1 upon formation of a 'phagocytic synapse'. Nature. 472: 471-5. PMID 21525931 DOI: 10.1038/Nature10071 |
0.415 |
|
| 2011 |
Limnander A, Depeille P, Freedman TS, Liou J, Leitges M, Kurosaki T, Roose JP, Weiss A. STIM1, PKC-δ and RasGRP set a threshold for proapoptotic Erk signaling during B cell development. Nature Immunology. 12: 425-33. PMID 21441934 DOI: 10.1038/Ni.2016 |
0.824 |
|
| 2011 |
Hesslein DG, Palacios EH, Sun JC, Beilke JN, Watson SR, Weiss A, Lanier LL. Differential requirements for CD45 in NK-cell function reveal distinct roles for Syk-family kinases. Blood. 117: 3087-95. PMID 21245479 DOI: 10.1182/Blood-2010-06-292219 |
0.827 |
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| 2011 |
Liontos LM, Dissanayake D, Ohashi PS, Weiss A, Dragone LL, McGlade CJ. The Src-like adaptor protein regulates GM-CSFR signaling and monocytic dendritic cell maturation. Journal of Immunology (Baltimore, Md. : 1950). 186: 1923-33. PMID 21220694 DOI: 10.4049/Jimmunol.0903292 |
0.428 |
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| 2010 |
Au-Yeung BB, Levin SE, Zhang C, Hsu LY, Cheng DA, Killeen N, Shokat KM, Weiss A. A genetically selective inhibitor demonstrates a function for the kinase Zap70 in regulatory T cells independent of its catalytic activity. Nature Immunology. 11: 1085-92. PMID 21037577 DOI: 10.1038/Ni.1955 |
0.753 |
|
| 2010 |
Beinke S, Phee H, Clingan JM, Schlessinger J, Matloubian M, Weiss A. Proline-rich tyrosine kinase-2 is critical for CD8 T-cell short-lived effector fate. Proceedings of the National Academy of Sciences of the United States of America. 107: 16234-9. PMID 20805505 DOI: 10.1073/Pnas.1011556107 |
0.526 |
|
| 2010 |
Wang H, Kadlecek TA, Au-Yeung BB, Goodfellow HE, Hsu LY, Freedman TS, Weiss A. ZAP-70: an essential kinase in T-cell signaling. Cold Spring Harbor Perspectives in Biology. 2: a002279. PMID 20452964 DOI: 10.1101/Cshperspect.A002279 |
0.844 |
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| 2010 |
Phee H, Dzhagalov I, Mollenauer M, Wang Y, Irvine DJ, Robey E, Weiss A. Regulation of thymocyte positive selection and motility by GIT2. Nature Immunology. 11: 503-11. PMID 20431621 DOI: 10.1038/Ni.1868 |
0.406 |
|
| 2010 |
Zikherman J, Jenne C, Watson S, Doan K, Raschke W, Goodnow CC, Weiss A. CD45-Csk Phosphatase-Kinase Titration Uncouples Basal and Inducible T Cell Receptor Signaling during Thymic Development Immunity. 32: 342-354. PMID 20346773 DOI: 10.1016/J.Immuni.2010.03.006 |
0.524 |
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| 2010 |
Weiss A. The right team at the right time to go for a home run: tyrosine kinase activation by the TCR. Nature Immunology. 11: 101-4. PMID 20084063 DOI: 10.1038/Ni0210-101 |
0.455 |
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| 2010 |
Nolan G, Baba Y, Matsumoto M, Kurosaki T, Veillette A, Weiss A, Cantrell D, Schwartzberg P. Lymphocyte signaling (SY4-1) Chairpersons: Tomohiro Kurosaki, Doreen Cantrell International Immunology. 22. DOI: 10.1093/Intimm/Dxq149 |
0.386 |
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| 2009 |
Deindl S, Kadlecek TA, Cao X, Kuriyan J, Weiss A. Stability of an autoinhibitory interface in the structure of the tyrosine kinase ZAP-70 impacts T cell receptor response Proceedings of the National Academy of Sciences of the United States of America. 106: 20699-20704. PMID 19920178 DOI: 10.1073/Pnas.0911512106 |
0.862 |
|
| 2009 |
Dragone LL, Shaw LA, Myers MD, Weiss A. SLAP, a regulator of immunoreceptor ubiquitination, signaling, and trafficking. Immunological Reviews. 232: 218-28. PMID 19909366 DOI: 10.1111/J.1600-065X.2009.00827.X |
0.756 |
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| 2009 |
Hsu LY, Tan YX, Xiao Z, Malissen M, Weiss A. A hypomorphic allele of ZAP-70 reveals a distinct thymic threshold for autoimmune disease versus autoimmune reactivity. The Journal of Experimental Medicine. 206: 2527-41. PMID 19841086 DOI: 10.1084/Jem.20082902 |
0.574 |
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| 2009 |
Weiss A. TCR signal transduction: opening the black box. Journal of Immunology (Baltimore, Md. : 1950). 183: 4821-7. PMID 19801506 DOI: 10.4049/Jimmunol.0990083 |
0.311 |
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| 2009 |
Charpentier X, Gabay JE, Reyes M, Zhu JW, Weiss A, Shuman HA. Chemical genetics reveals bacterial and host cell functions critical for type IV effector translocation by Legionella pneumophila. Plos Pathogens. 5: e1000501. PMID 19578436 DOI: 10.1371/Journal.Ppat.1000501 |
0.372 |
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| 2009 |
Chakraborty AK, Das J, Zikherman J, Yang M, Govern CC, Ho M, Weiss A, Roose J. Molecular origin and functional consequences of digital signaling and hysteresis during Ras activation in lymphocytes. Science Signaling. 2: pt2. PMID 19366993 DOI: 10.1126/Scisignal.266Pt2 |
0.328 |
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| 2009 |
Grochowy G, Hermiston ML, Kuhny M, Weiss A, Huber M. Requirement for CD45 in fine-tuning mast cell responses mediated by different ligand-receptor systems. Cellular Signalling. 21: 1277-86. PMID 19332117 DOI: 10.1016/J.Cellsig.2009.03.018 |
0.462 |
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| 2009 |
Zikherman J, Hermiston M, Steiner D, Hasegawa K, Chan A, Weiss A. PTPN22 deficiency cooperates with the CD45 E613R allele to break tolerance on a non-autoimmune background. Journal of Immunology (Baltimore, Md. : 1950). 182: 4093-106. PMID 19299707 DOI: 10.4049/Jimmunol.0803317 |
0.488 |
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| 2009 |
Au-Yeung BB, Deindl S, Hsu LY, Palacios EH, Levin SE, Kuriyan J, Weiss A. The structure, regulation, and function of ZAP-70 Immunological Reviews. 228: 41-57. PMID 19290920 DOI: 10.1111/J.1600-065X.2008.00753.X |
0.84 |
|
| 2009 |
Weiss A. Kinases and phosphatases of the immune system. Immunological Reviews. 228: 5-8. PMID 19290917 DOI: 10.1111/J.1600-065X.2009.00761.X |
0.37 |
|
| 2009 |
Senis YA, Tomlinson MG, Ellison S, Mazharian A, Lim J, Zhao Y, Kornerup KN, Auger JM, Thomas SG, Dhanjal T, Kalia N, Zhu JW, Weiss A, Watson SP. The tyrosine phosphatase CD148 is an essential positive regulator of platelet activation and thrombosis. Blood. 113: 4942-54. PMID 19246339 DOI: 10.1182/Blood-2008-08-174318 |
0.418 |
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| 2009 |
Zikherman J, Weiss A. Antigen receptor signaling in the rheumatic diseases. Arthritis Research & Therapy. 11: 202. PMID 19232064 DOI: 10.1186/Ar2528 |
0.478 |
|
| 2009 |
Das J, Ho M, Zikherman J, Govern C, Yang M, Weiss A, Chakraborty AK, Roose JP. Digital signaling and hysteresis characterize ras activation in lymphoid cells. Cell. 136: 337-51. PMID 19167334 DOI: 10.1016/J.Cell.2008.11.051 |
0.322 |
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| 2009 |
Hermiston ML, Zikherman J, Tan AL, Lam VC, Cresalia NM, Oksenberg N, Goren N, Brassat D, Oksenberg JR, Weiss A. Differential impact of the CD45 juxtamembrane wedge on central and peripheral T cell receptor responses. Proceedings of the National Academy of Sciences of the United States of America. 106: 546-51. PMID 19129486 DOI: 10.1073/Pnas.0811647106 |
0.556 |
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| 2009 |
Prasad A, Zikherman J, Das J, Roose JP, Weiss A, Chakraborty AK. Origin of the sharp boundary that discriminates positive and negative selection of thymocytes. Proceedings of the National Academy of Sciences of the United States of America. 106: 528-33. PMID 19098101 DOI: 10.1073/Pnas.0805981105 |
0.406 |
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| 2008 |
Zikherman J, Weiss A. Alternative splicing of CD45: the tip of the iceberg. Immunity. 29: 839-41. PMID 19100695 DOI: 10.1016/J.Immuni.2008.12.005 |
0.387 |
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| 2008 |
Louvet C, Szot GL, Lang J, Lee MR, Martinier N, Bollag G, Zhu S, Weiss A, Bluestone JA. Tyrosine kinase inhibitors reverse type 1 diabetes in nonobese diabetic mice. Proceedings of the National Academy of Sciences of the United States of America. 105: 18895-900. PMID 19015530 DOI: 10.1073/Pnas.0810246105 |
0.331 |
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| 2008 |
Gupta VA, Hermiston ML, Cassafer G, Daikh DI, Weiss A. B cells drive lymphocyte activation and expansion in mice with the CD45 wedge mutation and Fas deficiency. The Journal of Experimental Medicine. 205: 2755-61. PMID 19001138 DOI: 10.1084/Jem.20081204 |
0.619 |
|
| 2008 |
Mingueneau M, Sansoni A, Grégoire C, Roncagalli R, Aguado E, Weiss A, Malissen M, Malissen B. The proline-rich sequence of CD3epsilon controls T cell antigen receptor expression on and signaling potency in preselection CD4+CD8+ thymocytes. Nature Immunology. 9: 522-32. PMID 18408722 DOI: 10.1038/Ni.1608 |
0.483 |
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| 2008 |
Levin SE, Zhang C, Kadlecek TA, Shokat KM, Weiss A. Inhibition of ZAP-70 kinase activity via an analog-sensitive allele blocks T cell receptor and CD28 superagonist signaling. The Journal of Biological Chemistry. 283: 15419-30. PMID 18378687 DOI: 10.1074/Jbc.M709000200 |
0.759 |
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| 2008 |
Zhu JW, Brdicka T, Katsumoto TR, Lin J, Weiss A. Structurally distinct phosphatases CD45 and CD148 both regulate B cell and macrophage immunoreceptor signaling. Immunity. 28: 183-96. PMID 18249142 DOI: 10.1016/J.Immuni.2007.11.024 |
0.576 |
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| 2008 |
Chen L, Huynh L, Apgar J, Tang L, Rassenti L, Weiss A, Kipps TJ. ZAP-70 enhances IgM signaling independent of its kinase activity in chronic lymphocytic leukemia. Blood. 111: 2685-92. PMID 18048647 DOI: 10.1182/Blood-2006-12-062265 |
0.514 |
|
| 2007 |
Siggs OM, Miosge LA, Yates AL, Kucharska EM, Sheahan D, Brdicka T, Weiss A, Liston A, Goodnow CC. Opposing Functions of the T Cell Receptor Kinase ZAP-70 in Immunity and Tolerance Differentially Titrate in Response to Nucleotide Substitutions Immunity. 27: 912-926. PMID 18093540 DOI: 10.1016/J.Immuni.2007.11.013 |
0.507 |
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| 2007 |
Palacios EH, Weiss A. Distinct roles for Syk and ZAP-70 during early thymocyte development. The Journal of Experimental Medicine. 204: 1703-15. PMID 17606633 DOI: 10.1084/Jem.20070405 |
0.826 |
|
| 2007 |
Schmalzigaug R, Phee H, Davidson CE, Weiss A, Premont RT. Differential expression of the ARF GAP genes GIT1 and GIT2 in mouse tissues. The Journal of Histochemistry and Cytochemistry : Official Journal of the Histochemistry Society. 55: 1039-48. PMID 17565117 DOI: 10.1369/Jhc.7A7207.2007 |
0.344 |
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| 2007 |
Deindl S, Kadlecek TA, Brdicka T, Cao X, Weiss A, Kuriyan J. Structural Basis for the Inhibition of Tyrosine Kinase Activity of ZAP-70 Cell. 129: 735-746. PMID 17512407 DOI: 10.1016/J.Cell.2007.03.039 |
0.832 |
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| 2007 |
Chung SC, Limnander A, Kurosaki T, Weiss A, Korenbrot JI. Coupling Ca2+ store release to Icrac channel activation in B lymphocytes requires the activity of Lyn and Syk kinases. The Journal of Cell Biology. 177: 317-28. PMID 17452533 DOI: 10.1085/Jgp1295Oia1 |
0.418 |
|
| 2007 |
Roose JP, Mollenauer M, Ho M, Kurosaki T, Weiss A. Unusual interplay of two types of Ras activators, RasGRP and SOS, establishes sensitive and robust Ras activation in lymphocytes. Molecular and Cellular Biology. 27: 2732-45. PMID 17283063 DOI: 10.1128/Mcb.01882-06 |
0.328 |
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| 2007 |
Balachandran P, Dragone L, Garrity-Ryan L, Lemus A, Weiss A, Engel J. The ubiquitin ligase Cbl-b limits Pseudomonas aeruginosa exotoxin T-mediated virulence. The Journal of Clinical Investigation. 117: 419-27. PMID 17235393 DOI: 10.1172/Jci28792 |
0.382 |
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| 2007 |
Hermiston ML, Graaf FRd, Weiss A. A Point Mutation in the Juxtamembrane Wedge of CD45 Impacts Myeloid Development and Generates a Novel Model for Hemophagocytic Disorders in the Context of a MHC I-Restricted Transgene. Blood. 110: 317-317. DOI: 10.1182/Blood.V110.11.317.317 |
0.465 |
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| 2006 |
Dragone LL, Myers MD, White C, Gadwal S, Sosinowski T, Gu H, Weiss A. Src-like adaptor protein (SLAP) regulates B cell receptor levels in a c-Cbl-dependent manner. Proceedings of the National Academy of Sciences of the United States of America. 103: 18202-7. PMID 17110436 DOI: 10.1073/Pnas.0608965103 |
0.82 |
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| 2006 |
Nirula A, Ho M, Phee H, Roose J, Weiss A. Phosphoinositide-dependent kinase 1 targets protein kinase A in a pathway that regulates interleukin 4. The Journal of Experimental Medicine. 203: 1733-44. PMID 16785309 DOI: 10.1084/Jem.20051715 |
0.514 |
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| 2006 |
Hesslein DG, Takaki R, Hermiston ML, Weiss A, Lanier LL. Dysregulation of signaling pathways in CD45-deficient NK cells leads to differentially regulated cytotoxicity and cytokine production. Proceedings of the National Academy of Sciences of the United States of America. 103: 7012-7. PMID 16627620 DOI: 10.1073/Pnas.0601851103 |
0.555 |
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| 2006 |
Dragone LL, Myers MD, White C, Sosinowski T, Weiss A. SRC-like adaptor protein regulates B cell development and function. Journal of Immunology (Baltimore, Md. : 1950). 176: 335-45. PMID 16365426 DOI: 10.4049/Jimmunol.176.1.335 |
0.807 |
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| 2006 |
Myers MD, Sosinowski T, Dragone LL, White C, Band H, Gu H, Weiss A. Src-like adaptor protein regulates TCR expression on thymocytes by linking the ubiquitin ligase c-Cbl to the TCR complex. Nature Immunology. 7: 57-66. PMID 16327786 DOI: 10.1038/Ni1291 |
0.808 |
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| 2006 |
Chen L, Huynh L, Weiss A, Kipps TJ. ZAP-70 Enhances IgM Signaling in Chronic Lymphocytic Leukemia Cells Independent of Its Tyrosine Kinase Activity. Blood. 108: 585-585. DOI: 10.1182/Blood.V108.11.585.585 |
0.454 |
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| 2006 |
Hermiston ML, Cresalia NM, Lam V, Tan AL, Weiss A. The Phenotypic Consequences of an Activating Mutation in the Juxtamembrane Wedge of CD45 Is Sensitive to Genetic Modifiers. Blood. 108: 1730-1730. DOI: 10.1182/Blood.V108.11.1730.1730 |
0.365 |
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| 2005 |
Hermiston ML, Tan AL, Gupta VA, Majeti R, Weiss A. The juxtamembrane wedge negatively regulates CD45 function in B cells. Immunity. 23: 635-47. PMID 16356861 DOI: 10.1016/J.Immuni.2005.11.001 |
0.69 |
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| 2005 |
Weiss A. Discovering the TCR beta-chain by subtraction. Journal of Immunology (Baltimore, Md. : 1950). 175: 2769-70. PMID 16116159 DOI: 10.4049/Jimmunol.175.5.2769 |
0.424 |
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| 2005 |
Myers MD, Dragone LL, Weiss A. Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation. The Journal of Cell Biology. 170: 285-94. PMID 16027224 DOI: 10.1083/Jcb.200501164 |
0.749 |
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| 2005 |
Brdicka T, Kadlecek TA, Roose JP, Pastuszak AW, Weiss A. Intramolecular regulatory switch in ZAP-70: analogy with receptor tyrosine kinases. Molecular and Cellular Biology. 25: 4924-33. PMID 15923611 DOI: 10.1128/Mcb.25.12.4924-4933.2005 |
0.514 |
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| 2005 |
Roose JP, Mollenauer M, Gupta VA, Stone J, Weiss A. A diacylglycerol-protein kinase C-RasGRP1 pathway directs Ras activation upon antigen receptor stimulation of T cells. Molecular and Cellular Biology. 25: 4426-41. PMID 15899849 DOI: 10.1128/Mcb.25.11.4426-4441.2005 |
0.598 |
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| 2005 |
Phee H, Abraham RT, Weiss A. Dynamic recruitment of PAK1 to the immunological synapse is mediated by PIX independently of SLP-76 and Vav1. Nature Immunology. 6: 608-17. PMID 15864311 DOI: 10.1038/Ni1199 |
0.556 |
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| 2005 |
Levin SE, Weiss A. Twisting tails exposed: the evidence for TCR conformational change. The Journal of Experimental Medicine. 201: 489-92. PMID 15728230 DOI: 10.1084/Jem.20050179 |
0.637 |
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| 2005 |
Chen L, Apgar J, Huynh L, Dicker F, Giago-McGahan T, Rassenti L, Weiss A, Kipps TJ. ZAP-70 directly enhances IgM signaling in chronic lymphocytic leukemia. Blood. 105: 2036-41. PMID 15514014 DOI: 10.1182/Blood-2004-05-1715 |
0.396 |
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| 2004 |
Tomlinson MG, Heath VL, Turck CW, Watson SP, Weiss A. SHIP family inositol phosphatases interact with and negatively regulate the Tec tyrosine kinase. The Journal of Biological Chemistry. 279: 55089-96. PMID 15492005 DOI: 10.1074/Jbc.M408141200 |
0.437 |
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| 2004 |
Palacios EH, Weiss A. Function of the Src-family kinases, Lck and Fyn, in T-cell development and activation. Oncogene. 23: 7990-8000. PMID 15489916 DOI: 10.1038/Sj.Onc.1208074 |
0.864 |
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| 2004 |
Lin J, Zhu JW, Baker JE, Weiss A. Regulated expression of the receptor-like tyrosine phosphatase CD148 on hemopoietic cells. Journal of Immunology (Baltimore, Md. : 1950). 173: 2324-30. PMID 15294945 DOI: 10.4049/Jimmunol.173.4.2324 |
0.63 |
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| 2004 |
Kane LP, Mollenauer MN, Weiss A. A proline-rich motif in the C terminus of Akt contributes to its localization in the immunological synapse. Journal of Immunology (Baltimore, Md. : 1950). 172: 5441-9. PMID 15100285 DOI: 10.4049/Jimmunol.172.9.5441 |
0.537 |
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| 2004 |
Crotzer VL, Mabardy AS, Weiss A, Brodsky FM. T cell receptor engagement leads to phosphorylation of clathrin heavy chain during receptor internalization. The Journal of Experimental Medicine. 199: 981-91. PMID 15067034 DOI: 10.1084/Jem.20031105 |
0.589 |
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| 2004 |
Abraham RT, Weiss A. Jurkat T cells and development of the T-cell receptor signalling paradigm. Nature Reviews. Immunology. 4: 301-8. PMID 15057788 DOI: 10.1038/Nri1330 |
0.498 |
|
| 2004 |
Andres PG, Howland KC, Nirula A, Kane LP, Barron L, Dresnek D, Sadra A, Imboden J, Weiss A, Abbas AK. Distinct regions in the CD28 cytoplasmic domain are required for T helper type 2 differentiation. Nature Immunology. 5: 435-42. PMID 15004555 DOI: 10.1038/Ni1044 |
0.497 |
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| 2004 |
Tomlinson MG, Kane LP, Su J, Kadlecek TA, Mollenauer MN, Weiss A. Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec. Molecular and Cellular Biology. 24: 2455-66. PMID 14993283 DOI: 10.1128/Mcb.24.6.2455-2466.2004 |
0.578 |
|
| 2003 |
Roose JP, Diehn M, Tomlinson MG, Lin J, Alizadeh AA, Botstein D, Brown PO, Weiss A. T cell receptor-independent basal signaling via Erk and Abl kinases suppresses RAG gene expression. Plos Biology. 1: E53. PMID 14624253 DOI: 10.1371/Journal.Pbio.0000053 |
0.646 |
|
| 2003 |
Lin J, Weiss A. The tyrosine phosphatase CD148 is excluded from the immunologic synapse and down-regulates prolonged T cell signaling. The Journal of Cell Biology. 162: 673-82. PMID 12913111 DOI: 10.1083/Jcb.200303040 |
0.644 |
|
| 2003 |
Kuhné MR, Lin J, Yablonski D, Mollenauer MN, Ehrlich LI, Huppa J, Davis MM, Weiss A. Linker for activation of T cells, zeta-associated protein-70, and Src homology 2 domain-containing leukocyte protein-76 are required for TCR-induced microtubule-organizing center polarization. Journal of Immunology (Baltimore, Md. : 1950). 171: 860-6. PMID 12847255 DOI: 10.4049/Jimmunol.171.2.860 |
0.613 |
|
| 2003 |
Kane LP, Weiss A. The PI-3 kinase/Akt pathway and T cell activation: pleiotropic pathways downstream of PIP3. Immunological Reviews. 192: 7-20. PMID 12670391 DOI: 10.1034/J.1600-065X.2003.00008.X |
0.571 |
|
| 2003 |
Hartgroves LC, Lin J, Langen H, Zech T, Weiss A, Harder T. Synergistic assembly of linker for activation of T cells signaling protein complexes in T cell plasma membrane domains. The Journal of Biological Chemistry. 278: 20389-94. PMID 12646565 DOI: 10.1074/Jbc.M301212200 |
0.614 |
|
| 2003 |
Hermiston ML, Xu Z, Weiss A. CD45: a critical regulator of signaling thresholds in immune cells. Annual Review of Immunology. 21: 107-37. PMID 12414720 DOI: 10.1146/Annurev.Immunol.21.120601.140946 |
0.582 |
|
| 2002 |
Ehrlich LI, Ebert PJ, Krummel MF, Weiss A, Davis MM. Dynamics of p56lck translocation to the T cell immunological synapse following agonist and antagonist stimulation. Immunity. 17: 809-22. PMID 12479826 DOI: 10.1016/S1074-7613(02)00481-8 |
0.414 |
|
| 2002 |
Gilman AG, Simon MI, Bourne HR, Harris BA, Long R, Ross EM, Stull JT, Taussig R, Bourne HR, Arkin AP, Cobb MH, Cyster JG, Devreotes PN, Ferrell JE, Fruman D, ... ... Weiss A, et al. Overview of the Alliance for Cellular Signaling. Nature. 420: 703-6. PMID 12478301 DOI: 10.1038/Nature01304 |
0.6 |
|
| 2002 |
Chen L, Widhopf G, Huynh L, Rassenti L, Rai KR, Weiss A, Kipps TJ. Expression of ZAP-70 is associated with increased B-cell receptor signaling in chronic lymphocytic leukemia. Blood. 100: 4609-14. PMID 12393534 DOI: 10.1182/Blood-2002-06-1683 |
0.466 |
|
| 2002 |
Kane LP, Mollenauer MN, Xu Z, Turck CW, Weiss A. Akt-dependent phosphorylation specifically regulates Cot induction of NF-kappa B-dependent transcription. Molecular and Cellular Biology. 22: 5962-74. PMID 12138205 DOI: 10.1128/Mcb.22.16.5962-5974.2002 |
0.523 |
|
| 2002 |
Xu Z, Weiss A. Negative regulation of CD45 by differential homodimerization of the alternatively spliced isoforms. Nature Immunology. 3: 764-71. PMID 12134145 DOI: 10.1038/Ni822 |
0.609 |
|
| 2002 |
Xu Z, Stokoe D, Kane LP, Weiss A. The inducible expression of the tumor suppressor gene PTEN promotes apoptosis and decreases cell size by inhibiting the PI3K/Akt pathway in Jurkat T cells. Cell Growth & Differentiation : the Molecular Biology Journal of the American Association For Cancer Research. 13: 285-96. PMID 12133897 |
0.506 |
|
| 2002 |
Kane LP, Lin J, Weiss A. It's all Rel-ative: NF-kappaB and CD28 costimulation of T-cell activation. Trends in Immunology. 23: 413-20. PMID 12133805 DOI: 10.1016/S1471-4906(02)02264-0 |
0.624 |
|
| 2002 |
Hermiston ML, Xu Z, Majeti R, Weiss A. Reciprocal regulation of lymphocyte activation by tyrosine kinases and phosphatases. The Journal of Clinical Investigation. 109: 9-14. PMID 11781344 DOI: 10.1172/Jci14794 |
0.74 |
|
| 2002 |
Yablonski D, Weiss A. Mechanisms of signaling by the hematopoietic-specific adaptor proteins, SLP-76 and LAT and their B cell counterpart, BLNK/SLP-65. Advances in Immunology. 79: 93-128. PMID 11680012 DOI: 10.1016/S0065-2776(01)79003-7 |
0.51 |
|
| 2001 |
Majeti R, Weiss A. Regulatory mechanisms for receptor protein tyrosine phosphatases. Chemical Reviews. 101: 2441-8. PMID 11749382 DOI: 10.1021/Cr000085M |
0.611 |
|
| 2001 |
Bromley SK, Iaboni A, Davis SJ, Whitty A, Green JM, Shaw AS, Weiss A, Dustin ML. The immunological synapse and CD28-CD80 interactions. Nature Immunology. 2: 1159-66. PMID 11713465 DOI: 10.1038/Ni737 |
0.47 |
|
| 2001 |
Sosinowski T, Killeen N, Weiss A. The Src-like adaptor protein downregulates the T cell receptor on CD4+CD8+ thymocytes and regulates positive selection. Immunity. 15: 457-66. PMID 11567635 DOI: 10.1016/S1074-7613(01)00195-9 |
0.787 |
|
| 2001 |
Barcellos LF, Caillier S, Dragone L, Elder M, Vittinghoff E, Bucher P, Lincoln RR, Pericak-Vance M, Haines JL, Weiss A, Hauser SL, Oksenberg JR. PTPRC (CD45) is not associated with the development of multiple sclerosis in U.S. patients. Nature Genetics. 29: 23-4. PMID 11528386 DOI: 10.1038/Ng722 |
0.306 |
|
| 2001 |
Sauer K, Liou J, Singh SB, Yablonski D, Weiss A, Perlmutter RM. Hematopoietic progenitor kinase 1 associates physically and functionally with the adaptor proteins B cell linker protein and SLP-76 in lymphocytes. The Journal of Biological Chemistry. 276: 45207-16. PMID 11487585 DOI: 10.1074/Jbc.M106811200 |
0.733 |
|
| 2001 |
Shapiro VS, Mollenauer MN, Weiss A. Endogenous CD28 expressed on myeloma cells up-regulates interleukin-8 production: implications for multiple myeloma progression. Blood. 98: 187-93. PMID 11418479 DOI: 10.1182/Blood.V98.1.187 |
0.411 |
|
| 2001 |
Lin J, Weiss A. Identification of the minimal tyrosine residues required for linker for activation of T cell function. The Journal of Biological Chemistry. 276: 29588-95. PMID 11395491 DOI: 10.1074/Jbc.M102221200 |
0.679 |
|
| 2001 |
Yablonski D, Kadlecek T, Weiss A. Identification of a Phospholipase C-γ1 (PLC-γ1) SH3 Domain-Binding Site in SLP-76 Required for T-Cell Receptor-Mediated Activation of PLC-γ1 and NFAT Molecular and Cellular Biology. 21: 4208-4218. PMID 11390650 DOI: 10.1128/Mcb.21.13.4208-4218.2001 |
0.551 |
|
| 2001 |
Lynch KW, Weiss A. A CD45 polymorphism associated with multiple sclerosis disrupts an exonic splicing silencer. The Journal of Biological Chemistry. 276: 24341-7. PMID 11306584 DOI: 10.1074/Jbc.M102175200 |
0.336 |
|
| 2001 |
Arnold R, Liou J, Drexler HC, Weiss A, Kiefer F. Caspase-mediated cleavage of hematopoietic progenitor kinase 1 (HPK1) converts an activator of NFkappaB into an inhibitor of NFkappaB. The Journal of Biological Chemistry. 276: 14675-84. PMID 11278403 DOI: 10.1074/Jbc.M008343200 |
0.665 |
|
| 2001 |
Baker JE, Majeti R, Tangye SG, Weiss A. Protein tyrosine phosphatase CD148-mediated inhibition of T-cell receptor signal transduction is associated with reduced LAT and phospholipase Cgamma1 phosphorylation. Molecular and Cellular Biology. 21: 2393-403. PMID 11259588 DOI: 10.1128/Mcb.21.7.2393-2403.2001 |
0.722 |
|
| 2001 |
Kratchmarova I, Sosinowski T, Weiss A, Witter K, Vincenz C, Pandey A. Characterization of promoter region and genomic structure of the murine and human genes encoding Src like adapter protein. Gene. 262: 267-73. PMID 11179692 DOI: 10.1016/S0378-1119(00)00516-3 |
0.806 |
|
| 2001 |
Ku GM, Yablonski D, Manser E, Lim L, Weiss A. A PAK1-PIX-PKL complex is activated by the T-cell receptor independent of Nck, Slp-76 and LAT. The Embo Journal. 20: 457-65. PMID 11157752 DOI: 10.1093/Emboj/20.3.457 |
0.787 |
|
| 2001 |
Lin J, Weiss A. T cell receptor signalling. Journal of Cell Science. 114: 243-4. PMID 11148124 |
0.578 |
|
| 2001 |
Kane LP, Andres PG, Howland KC, Abbas AK, Weiss A. Akt provides the CD28 costimulatory signal for up-regulation of IL-2 and IFN-gamma but not TH2 cytokines. Nature Immunology. 2: 37-44. PMID 11135576 DOI: 10.1038/83144 |
0.47 |
|
| 2001 |
Elder ME, Skoda-Smith S, Kadlecek TA, Wang F, Wu J, Weiss A. Distinct T cell developmental consequences in humans and mice expressing identical mutations in the DLAARN motif of ZAP-70. Journal of Immunology (Baltimore, Md. : 1950). 166: 656-61. PMID 11123350 DOI: 10.4049/Jimmunol.166.1.656 |
0.526 |
|
| 2001 |
Weiss A. Dimerization of the CD45 RPTPase inhibits its function in vivo and is necessary in order to prevent autoimmunity Biochemical Society Transactions. 29. DOI: 10.1042/Bst029A102A |
0.313 |
|
| 2000 |
Majeti R, Xu Z, Parslow TG, Olson JL, Daikh DI, Killeen N, Weiss A. An inactivating point mutation in the inhibitory wedge of CD45 causes lymphoproliferation and autoimmunity. Cell. 103: 1059-70. PMID 11163182 DOI: 10.1016/S0092-8674(00)00209-9 |
0.644 |
|
| 2000 |
Tomlinson MG, Lin J, Weiss A. Lymphocytes with a complex: adapter proteins in antigen receptor signaling. Immunology Today. 21: 584-91. PMID 11094263 DOI: 10.1016/S0167-5699(00)01716-3 |
0.603 |
|
| 2000 |
Irving BA, Weiss A. Surface chimeric receptors as tools in study of lymphocyte activation. Methods in Enzymology. 327: 210-228. PMID 11044985 DOI: 10.1016/S0076-6879(00)27278-9 |
0.432 |
|
| 2000 |
Roose J, Weiss A. T cells: getting a GRP on Ras. Nature Immunology. 1: 275-276. PMID 11017094 DOI: 10.1038/79713 |
0.332 |
|
| 2000 |
Genot EM, Arrieumerlou C, Ku G, Burgering BM, Weiss A, Kramer IM. The T-cell receptor regulates Akt (protein kinase B) via a pathway involving Rac1 and phosphatidylinositide 3-kinase. Molecular and Cellular Biology. 20: 5469-78. PMID 10891487 DOI: 10.1128/Mcb.20.15.5469-5478.2000 |
0.802 |
|
| 2000 |
Liou J, Kiefer F, Dang A, Hashimoto A, Cobb MH, Kurosaki T, Weiss A. HPK1 is activated by lymphocyte antigen receptors and negatively regulates AP-1. Immunity. 12: 399-408. PMID 10795738 DOI: 10.1016/S1074-7613(00)80192-2 |
0.689 |
|
| 2000 |
Kane LP, Lin J, Weiss A. Signal transduction by the TCR for antigen. Current Opinion in Immunology. 12: 242-9. PMID 10781399 DOI: 10.1016/S0952-7915(00)00083-2 |
0.632 |
|
| 2000 |
Sosinowski T, Pandey A, Dixit VM, Weiss A. Src-like adaptor protein (SLAP) is a negative regulator of T cell receptor signaling. The Journal of Experimental Medicine. 191: 463-74. PMID 10662792 DOI: 10.1084/Jem.191.3.463 |
0.85 |
|
| 2000 |
Witherden D, van Oers N, Waltzinger C, Weiss A, Benoist C, Mathis D. Tetracycline-controllable selection of CD4(+) T cells: half-life and survival signals in the absence of major histocompatibility complex class II molecules. The Journal of Experimental Medicine. 191: 355-64. PMID 10637279 DOI: 10.1084/Jem.191.2.355 |
0.46 |
|
| 2000 |
Kuhne MR, Ku G, Weiss A. A guanine nucleotide exchange factor-independent function of Vav1 in transcriptional activation Journal of Biological Chemistry. 275: 2185-2190. PMID 10636924 DOI: 10.1074/Jbc.275.3.2185 |
0.788 |
|
| 2000 |
Lynch KW, Weiss A. A model system for activation-induced alternative splicing of CD45 pre-mRNA in T cells implicates protein kinase C and Ras. Molecular and Cellular Biology. 20: 70-80. PMID 10594010 DOI: 10.1128/Mcb.20.1.70-80.2000 |
0.516 |
|
| 1999 |
Finco TS, Yablonski D, Lin J, Weiss A. The adapter proteins LAT and SLP-76 are required for T-cell activation. Cold Spring Harbor Symposia On Quantitative Biology. 64: 265-74. PMID 11232295 DOI: 10.1101/Sqb.1999.64.265 |
0.591 |
|
| 1999 |
Lin J, Weiss A, Finco TS. Localization of LAT in glycolipid-enriched microdomains is required for T cell activation. The Journal of Biological Chemistry. 274: 28861-4. PMID 10506128 DOI: 10.1074/Jbc.274.41.28861 |
0.648 |
|
| 1999 |
Kane LP, Shapiro VS, Stokoe D, Weiss A. Induction of NF-κB by the Akt/PKB kinase Current Biology. 9: 601-604. PMID 10359702 DOI: 10.1016/S0960-9822(99)80265-6 |
0.472 |
|
| 1999 |
Lagunoff M, Majeti R, Weiss A, Ganem D. Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus. Proceedings of the National Academy of Sciences of the United States of America. 96: 5704-9. PMID 10318948 DOI: 10.1073/Pnas.96.10.5704 |
0.611 |
|
| 1999 |
Zhao Q, Williams BL, Abraham RT, Weiss A. Interdomain B in ZAP-70 regulates but is not required for ZAP-70 signaling function in lymphocytes. Molecular and Cellular Biology. 19: 948-56. PMID 9858619 DOI: 10.1128/Mcb.19.1.948 |
0.541 |
|
| 1999 |
Chu DH, Morita CT, Weiss A. The Syk family of protein tyrosine kinases in T-cell activation and development. Immunological Reviews. 165: 167-80. PMID 9850860 DOI: 10.1111/J.1600-065X.1998.Tb01238.X |
0.555 |
|
| 1998 |
Finco TS, Kadlecek T, Zhang W, Samelson LE, Weiss A. LAT is required for TCR-mediated activation of PLCgamma1 and the Ras pathway. Immunity. 9: 617-26. PMID 9846483 DOI: 10.1016/S1074-7613(00)80659-7 |
0.519 |
|
| 1998 |
Yablonski D, Kane LP, Qian D, Weiss A. A Nck-Pak1 signaling module is required for T-cell receptor-mediated activation of NFAT, but not of JNK The Embo Journal. 17: 5647-5657. PMID 9755165 DOI: 10.1093/Emboj/17.19.5647 |
0.546 |
|
| 1998 |
Weiss A, Schlessinger J. Switching signals on or off by receptor dimerization. Cell. 94: 277-80. PMID 9708728 DOI: 10.1016/S0092-8674(00)81469-5 |
0.357 |
|
| 1998 |
Yablonski D, Kuhne MR, Kadlecek T, Weiss A. Uncoupling of nonreceptor tyrosine kinases from PLC-gamma1 in an SLP-76-deficient T cell. Science (New York, N.Y.). 281: 413-6. PMID 9665884 DOI: 10.1126/Science.281.5375.413 |
0.571 |
|
| 1998 |
Grazioli L, Germain V, Weiss A, Acuto O. Anti-peptide antibodies detect conformational changes of the inter-SH2 domain of ZAP-70 due to binding to the zeta chain and to intramolecular interactions. Journal of Biological Chemistry. 273: 8916-8921. PMID 9535874 DOI: 10.1074/Jbc.273.15.8916 |
0.378 |
|
| 1998 |
Lowin-Kropf B, Shapiro VS, Weiss A. Cytoskeletal polarization of T cells is regulated by an immunoreceptor tyrosine-based activation motif-dependent mechanism. Journal of Cell Biology. 140: 861-871. PMID 9472038 DOI: 10.1083/Jcb.140.4.861 |
0.551 |
|
| 1998 |
Majeti R, Bilwes AM, Noel JP, Hunter T, Weiss A. Dimerization-induced inhibition of receptor protein tyrosine phosphatase function through an inhibitory wedge. Science (New York, N.Y.). 279: 88-91. PMID 9417031 DOI: 10.1126/Science.279.5347.88 |
0.676 |
|
| 1998 |
Liao XC, Littman DR, Weiss A. Itk and Fyn make independent contributions to T cell activation. The Journal of Experimental Medicine. 186: 2069-73. PMID 9396778 DOI: 10.1084/Jem.186.12.2069 |
0.488 |
|
| 1998 |
DeFranco AL, Weiss A. Lymphocyte activation and effector functions. Turning lymphocytes on and off Current Opinion in Immunology. 10: 243-244. DOI: 10.1016/S0952-7915(98)80160-X |
0.372 |
|
| 1997 |
Petricoin EF, Ito S, Williams BL, Audet S, Stancato LF, Gamero A, Clouse K, Grimley P, Weiss A, Beeler J, Finbloom DS, Shores EW, Abraham R, Larner AC. Antiproliferative action of interferon-alpha requires components of T-cell-receptor signalling. Nature. 390: 629-32. PMID 9403695 DOI: 10.1038/37648 |
0.536 |
|
| 1997 |
Liao XC, Fournier S, Killeen N, Weiss A, Allison JP, Littman DR. Itk negatively regulates induction of T cell proliferation by CD28 costimulation Journal of Experimental Medicine. 186: 221-228. PMID 9221751 DOI: 10.1084/Jem.186.2.221 |
0.508 |
|
| 1997 |
Shapiro VS, Truitt KE, Imboden JB, Weiss A. CD28 mediates transcriptional upregulation of the interleukin-2 (IL-2) promoter through a composite element containing the CD28RE and NF-IL-2B AP-1 sites. Molecular and Cellular Biology. 17: 4051-8. PMID 9199340 DOI: 10.1128/Mcb.17.7.4051 |
0.341 |
|
| 1997 |
Huby RD, Iwashima M, Weiss A, Ley SC. ZAP-70 protein tyrosine kinase is constitutively targeted to the T cell cortex independently of its SH2 domains. The Journal of Cell Biology. 137: 1639-49. PMID 9199177 DOI: 10.1083/Jcb.137.7.1639 |
0.538 |
|
| 1997 |
Wu J, Zhao Q, Kurosaki T, Weiss A. The Vav binding site (Y315) in ZAP-70 is critical for antigen receptor-mediated signal transduction. The Journal of Experimental Medicine. 185: 1877-82. PMID 9151714 DOI: 10.1084/Jem.185.10.1877 |
0.548 |
|
| 1997 |
Qian D, Lev S, van Oers NS, Dikic I, Schlessinger J, Weiss A. Tyrosine phosphorylation of Pyk2 is selectively regulated by Fyn during TCR signaling. The Journal of Experimental Medicine. 185: 1253-9. PMID 9104812 DOI: 10.1084/Jem.185.7.1253 |
0.558 |
|
| 1997 |
Qian D, Weiss A. T cell antigen receptor signal transduction Current Opinion in Cell Biology. 9: 205-212. PMID 9069257 DOI: 10.1016/S0955-0674(97)80064-6 |
0.56 |
|
| 1997 |
Page ST, Van Oers NSC, Perlmutter RM, Weiss A, Pullen AM. Differential contribution of Lck and Fyn protein tyrosine kinases to intraepithelial lymphocyte development European Journal of Immunology. 27: 554-562. PMID 9045930 DOI: 10.1002/Eji.1830270229 |
0.502 |
|
| 1996 |
Oers NSCv, Lowin-Kropf B, Finlay D, Connolly K, Weiss A. αβ T Cell Development Is Abolished in Mice Lacking Both Lck and Fyn Protein Tyrosine Kinases Immunity. 5: 429-436. PMID 8934570 DOI: 10.1016/S1074-7613(00)80499-9 |
0.492 |
|
| 1996 |
Taylor N, Bacon KB, Smith S, Jahn T, Kadlecek TA, Uribe L, Kohn DB, Gelfand EW, Weiss A, Weinberg K. Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene Journal of Experimental Medicine. 184: 2031-2036. PMID 8920891 DOI: 10.1084/Jem.184.5.2031 |
0.571 |
|
| 1996 |
Shapiro VS, Mollenauer MN, Greene WC, Weiss A. c-Rel regulation of IL-2 gene expression may be mediated through activation of AP-1 Journal of Experimental Medicine. 184: 1663-1669. PMID 8920856 DOI: 10.1084/Jem.184.5.1663 |
0.333 |
|
| 1996 |
Fry AM, Lanier LL, Weiss A. Phosphotyrosines in the killer cell inhibitory receptor motif of NKB1 are required for negative signaling and for association with protein tyrosine phosphatase 1C. The Journal of Experimental Medicine. 184: 295-300. PMID 8691146 DOI: 10.1084/Jem.184.1.295 |
0.578 |
|
| 1996 |
Wu J, Motto DG, Koretzky GA, Weiss A. Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation. Immunity. 4: 593-602. PMID 8673706 DOI: 10.1016/S1074-7613(00)80485-9 |
0.519 |
|
| 1996 |
Van Oers NSC, Killeen N, Weiss A. Lck regulates the tyrosine phosphorylation of the T cell receptor subunits and ZAP-70 in murine thymocytes Journal of Experimental Medicine. 183: 1053-1062. PMID 8642247 DOI: 10.1084/Jem.183.3.1053 |
0.564 |
|
| 1996 |
Qian D, Mollenauer MN, Weiss A. Dominant-negative Zeta-associated protein 70 inhibits T cell antigen receptor signaling Journal of Experimental Medicine. 183: 611-620. PMID 8627172 DOI: 10.1084/Jem.183.2.611 |
0.566 |
|
| 1996 |
Straus DB, Chan AC, Patai B, Weiss A. SH2 domain function is essential for the role of the Lck tyrosine kinase in T cell receptor signal transduction. The Journal of Biological Chemistry. 271: 9976-81. PMID 8626636 DOI: 10.1074/Jbc.271.17.9976 |
0.576 |
|
| 1996 |
Chu DH, Spits H, Peyron JF, Rowley RB, Bolen JB, Weiss A. The Syk protein tyrosine kinase can function independently of CD45 or Lck in T cell antigen receptor signaling. The Embo Journal. 15: 6251-6261. DOI: 10.1002/J.1460-2075.1996.Tb01015.X |
0.6 |
|
| 1995 |
Crooks MEC, Littman DR, Carter RH, Fearon DT, Weiss A, Stein PH. CD28-mediated costimulation in the absence of phosphatidylinositol 3-kinase association and activation Molecular and Cellular Biology. 15: 6820-6828. PMID 8524248 DOI: 10.1128/Mcb.15.12.6820 |
0.566 |
|
| 1995 |
Oers NSCv, Weiss A. The Syk/ZAP-70 protein tyrosine kinase connection to antigen receptor signalling processes. Seminars in Immunology. 7: 227-236. PMID 8520027 DOI: 10.1006/Smim.1995.0027 |
0.533 |
|
| 1995 |
Weiss AP, Olmedo ML, Lin JC, Ballock RT. Growth factor modulation of the formation of a molded vascularized bone graft in vivo. The Journal of Hand Surgery. 20: 94-100. PMID 7722273 |
0.357 |
|
| 1995 |
Howe LR, Weiss A. Multiple kinases mediate T-cell-receptor signalling Trends in Biochemical Sciences. 20: 59-64. PMID 7701563 DOI: 10.1016/S0968-0004(00)88958-6 |
0.589 |
|
| 1995 |
Oers NSCV, Boehmer HV, Weiss A. The pre-T cell receptor (TCR) complex is functionally coupled to the TCR-zeta subunit. Journal of Experimental Medicine. 182: 1585-1590. PMID 7595229 DOI: 10.1084/Jem.182.5.1585 |
0.533 |
|
| 1995 |
Fargnoli J, Burkhardt AL, Laverty M, Kut SA, Van Oers NSC, Weiss A, Bolen JB. Syk mutation in Jurkat E6-derived clones results in lack of p72syk expression Journal of Biological Chemistry. 270: 26533-26537. PMID 7592872 DOI: 10.1074/Jbc.270.44.26533 |
0.48 |
|
| 1995 |
Gelfand EW, Weinberg K, Mazer BD, Kadlecek TA, Weiss A. Absence of ZAP-70 prevents signaling through the antigen receptor on peripheral blood T cells but not on thymocytes. The Journal of Experimental Medicine. 182: 1057-65. PMID 7561679 DOI: 10.1084/Jem.182.4.1057 |
0.538 |
|
| 1995 |
Weiss A. Molecular and genetic insights into the role of protein tyrosine kinases in T cell receptor signaling Clinical Immunology and Immunopathology. 76. PMID 7554459 DOI: 10.1016/S0090-1229(95)90054-3 |
0.54 |
|
| 1995 |
Weiss A, Kadlecek T, Iwashima M, Chan A, Van Oers N. Molecular and genetic insights into T-cell antigen receptor signaling. Annals of the New York Academy of Sciences. 766: 149-56. PMID 7486651 DOI: 10.1111/J.1749-6632.1995.Tb26658.X |
0.466 |
|
| 1994 |
Weiss A, Littman DR. Signal transduction by lymphocyte antigen receptors. Cell. 76: 263-74. PMID 8293463 DOI: 10.1016/0092-8674(94)90334-4 |
0.517 |
|
| 1994 |
Chan AC, Kadlecek TA, Elder ME, Filipovich AH, Kuo WL, Iwashima M, Parslow TG, Weiss A. ZAP-70 deficiency in an autosomal recessive form of severe combined immunodeficiency Science. 264: 1599-1601. PMID 8202713 DOI: 10.1126/Science.8202713 |
0.543 |
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| 1994 |
Elder ME, Lin D, Clever J, Chan AC, Hope TJ, Weiss A, Parslow TG. Human severe combined immunodeficiency due to a defect in ZAP-70, a T cell tyrosine kinase Science. 264: 1596-1599. PMID 8202712 DOI: 10.1126/Science.8202712 |
0.57 |
|
| 1994 |
Stein PH, Fraser JD, Weiss A. The cytoplasmic domain of CD28 is both necessary and sufficient for costimulation of interleukin-2 secretion and association with phosphatidylinositol 3'-kinase. Molecular and Cellular Biology. 14: 3392-402. PMID 8164687 DOI: 10.1128/Mcb.14.5.3392 |
0.495 |
|
| 1994 |
Desai DM, Sap J, Silvennoinen O, Schlessinger J, Weiss A. The catalytic activity of the CD45 membrane-proximal phosphatase domain is required for TCR signaling and regulation. The Embo Journal. 13: 4002-10. PMID 8076596 DOI: 10.1002/J.1460-2075.1994.Tb06716.X |
0.528 |
|
| 1994 |
Chan AC, Desai DM, Weiss A. The role of protein tyrosine kinases and protein tyrosine phosphatases in T cell antigen receptor signal transduction Annual Review of Immunology. 12: 555-592. PMID 8011291 DOI: 10.1146/Annurev.Iy.12.040194.003011 |
0.58 |
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| 1994 |
Izquierdo M, Leevers SJ, Williams DH, Marshall CJ, Weiss A, Cantrell D. The role of protein kinase C in the regulation of extracellular signal-regulated kinase by the T cell antigen receptor. European Journal of Immunology. 24: 2462-8. PMID 7925576 DOI: 10.1002/Eji.1830241031 |
0.547 |
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| 1994 |
Weiss A, Iwashima M, Irving B, van Oers NS, Kadlecek TA, Straus D, Chan A. Molecular and genetic insights into T cell antigen receptor signal transduction. Advances in Experimental Medicine and Biology. 365: 53-62. PMID 7887313 DOI: 10.1007/978-1-4899-0987-9_6 |
0.502 |
|
| 1994 |
Sieh M, Batzer A, Schlessinger J, Weiss A. GRB2 and phospholipase C-gamma 1 associate with a 36- to 38-kilodalton phosphotyrosine protein after T-cell receptor stimulation. Molecular and Cellular Biology. 14: 4435-42. PMID 7516467 DOI: 10.1128/Mcb.14.7.4435 |
0.493 |
|
| 1994 |
van Oers NS, Teh SJ, Irving BA, Tiong J, Weiss A, Teh HS. Production and characterization of monoclonal antibodies specific for the murine T cell receptor zeta chain. Journal of Immunological Methods. 170: 261-8. PMID 7512608 DOI: 10.1016/0022-1759(94)90401-4 |
0.476 |
|
| 1994 |
Iwashima M, Irving BA, van Oers NS, Chan AC, Weiss A. Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases. Science (New York, N.Y.). 263: 1136-9. PMID 7509083 DOI: 10.1126/Science.7509083 |
0.552 |
|
| 1993 |
Desai DM, Sap J, Schlessinger J, Weiss A. Ligand-mediated negative regulation of a chimeric transmembrane receptor tyrosine phosphatase. Cell. 73: 541-54. PMID 8490965 DOI: 10.1016/0092-8674(93)90141-C |
0.492 |
|
| 1993 |
Weiss A. T cell antigen receptor signal transduction: A tale of tails and cytoplasmic protein-tyrosine kinases Cell. 73: 209-212. PMID 8477442 DOI: 10.1016/0092-8674(93)90221-B |
0.539 |
|
| 1993 |
Irving BA, Chan AC, Weiss A. Functional characterization of a signal transducing motif present in the T cell antigen receptor zeta chain. The Journal of Experimental Medicine. 177: 1093-103. PMID 8459204 DOI: 10.1084/Jem.177.4.1093 |
0.556 |
|
| 1993 |
Fraser JD, Straus D, Weiss A. Signal transduction events leading to T-cell lymphokine gene expression. Immunology Today. 14: 357-62. PMID 8363726 DOI: 10.1016/0167-5699(93)90236-E |
0.493 |
|
| 1993 |
Straus DB, Weiss A. The CD3 chains of the T cell antigen receptor associate with the ZAP-70 tyrosine kinase and are tyrosine phosphorylated after receptor stimulation. Journal of Experimental Medicine. 178: 1523-1530. PMID 7693848 DOI: 10.1084/Jem.178.5.1523 |
0.531 |
|
| 1993 |
Graber M, June CH, Samelson LE, Weiss A. The protein tyrosine kinase inhibitor herbimycin A, but not genistein, specifically inhibits signal transduction by the T cell antigen receptor. International Immunology. 4: 1201-10. PMID 1472473 DOI: 10.1093/Intimm/4.11.1201 |
0.556 |
|
| 1993 |
Sieh M, Bolen JB, Weiss A. CD45 specifically modulates binding of Lck to a phosphopeptide encompassing the negative regulatory tyrosine of Lck. The Embo Journal. 12: 315-321. DOI: 10.1002/J.1460-2075.1993.Tb05659.X |
0.499 |
|
| 1992 |
Margolis B, Hu P, Katzav S, Li W, Oliver JM, Ullrich A, Weiss A, Schlessinger J. Tyrosine phosphorylation of vav proto-oncogene product containing SH2 domain and transcription factor motifs. Nature. 356: 71-4. PMID 1531699 DOI: 10.1038/356071A0 |
0.545 |
|
| 1992 |
Straus DB, Weiss A. Genetic evidence for the involvement of the lck tyrosine kinase in signal transduction through the T cell antigen receptor. Cell. 70: 585-593. PMID 1505025 DOI: 10.1016/0092-8674(92)90428-F |
0.581 |
|
| 1992 |
Chan AC, Iwashima M, Turck CW, Weiss A. ZAP-70: A 70 kd protein-tyrosine kinase that associates with the TCR ζ chain Cell. 71: 649-662. PMID 1423621 DOI: 10.1016/0092-8674(92)90598-7 |
0.576 |
|
| 1992 |
Chan AC, Irving BA, Weiss A. New insights into T-cell antigen receptor structure and signal transduction. Current Opinion in Immunology. 4: 246-51. PMID 1418701 DOI: 10.1016/0952-7915(92)90072-M |
0.588 |
|
| 1992 |
Weiss A, Chan AC, Iwashima M, Straus D, Irving BA. Regulation of protein tyrosine kinase activation by the T-cell antigen receptor zeta chain. Cold Spring Harbor Symposia On Quantitative Biology. 57: 107-16. PMID 1339649 DOI: 10.1101/Sqb.1992.057.01.014 |
0.554 |
|
| 1992 |
Fraser JD, Weiss A. Regulation of T-cell lymphokine gene transcription by the accessory molecule CD28. Molecular and Cellular Biology. 12: 4357-63. PMID 1328852 DOI: 10.1128/Mcb.12.10.4357 |
0.469 |
|
| 1992 |
Fraser JD, Newton ME, Weiss A. CD28 and T cell antigen receptor signal transduction coordinately regulate interleukin 2 gene expression in response to superantigen stimulation. The Journal of Experimental Medicine. 175: 1131-4. PMID 1313075 DOI: 10.1084/Jem.175.4.1131 |
0.525 |
|
| 1991 |
Fraser JD, Irving BA, Crabtree GR, Weiss A. Regulation of interleukin-2 gene enhancer activity by the T cell accessory molecule CD28. Science (New York, N.Y.). 251: 313-6. PMID 1846244 DOI: 10.1126/Science.1846244 |
0.456 |
|
| 1991 |
Weiss A. Molecular and genetic insights into T cell antigen receptor structure and function Annual Review of Genetics. 25: 487-510. PMID 1839878 DOI: 10.1146/Annurev.Ge.25.120191.002415 |
0.417 |
|
| 1991 |
Tan L, Turner J, Weiss A. Regions of the T cell receptor alpha and beta chains that are responsible for interactions with CD3. The Journal of Experimental Medicine. 173: 1247-56. PMID 1827143 DOI: 10.1084/Jem.173.5.1247 |
0.426 |
|
| 1991 |
Chan AC, Irving BA, Fraser JD, Weiss A. The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. Proceedings of the National Academy of Sciences of the United States of America. 88: 9166-70. PMID 1717999 DOI: 10.1073/Pnas.88.20.9166 |
0.549 |
|
| 1991 |
Irving BA, Weiss A. The cytoplasmic domain of the T cell receptor ζ chain is sufficient to couple to receptor-associated signal transduction pathways Cell. 64: 891-901. PMID 1705867 DOI: 10.1016/0092-8674(91)90314-O |
0.507 |
|
| 1991 |
Koretzky GA, Picus J, Schultz T, Weiss A. Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production. Proceedings of the National Academy of Sciences of the United States of America. 88: 2037-41. PMID 1672451 DOI: 10.1073/Pnas.88.6.2037 |
0.528 |
|
| 1991 |
Chan AC, Irving BA, Fraser JD, Weiss A. The zeta chain is associated with a tyrosine kinase and upon T-cell antigen receptor stimulation associates with ZAP-70, a 70-kDa tyrosine phosphoprotein. Proceedings of the National Academy of Sciences. 88: 9166-9170. DOI: 10.1073/PNAS.88.20.9166 |
0.403 |
|
| 1991 |
Weiss A, Koretzky G, Schatzman RC, Kadlecek T. Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1. Proceedings of the National Academy of Sciences. 88: 5484-5488. DOI: 10.1073/Pnas.88.13.5484 |
0.559 |
|
| 1990 |
Desai DM, Newton ME, Kadlecek T, Weiss A. Stimulation of the phosphatidyl-inositol pathway can induce T-cell activation Nature. 348: 66-69. PMID 2234059 DOI: 10.1038/348066A0 |
0.58 |
|
| 1990 |
Weiss A. Structure and function of the T cell antigen receptor Journal of Clinical Investigation. 86: 1015-1022. PMID 2211998 DOI: 10.1172/Jci114803 |
0.448 |
|
| 1990 |
Desai DM, Goldsmith MA, Weiss A. A transfected human muscarinic receptor fails to substitute for the T cell antigen receptor complex in CD2-initiated signal transduction International Immunology. 2: 615-620. PMID 1980618 DOI: 10.1093/Intimm/2.7.615 |
0.555 |
|
| 1990 |
Koretzky GA, Picus J, Thomas ML, Weiss A. Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway Nature. 346: 66-68. DOI: 10.1038/346066A0 |
0.506 |
|
| 1989 |
Fraser JD, Goldsmith MA, Weiss A. Ligand-induced association between the T-cell antigen receptor and two glycoproteins Proceedings of the National Academy of Sciences of the United States of America. 86: 7133-7137. PMID 2789381 DOI: 10.1073/Pnas.86.18.7133 |
0.476 |
|
| 1989 |
Goldsmith MA, Bockenstedt LK, Dazin P, Weiss A. Use of somatic cell mutants to study the signal transduction function of the T cell antigen receptor Advances in Experimental Medicine and Biology. 254: 25-33. PMID 2573246 DOI: 10.1007/978-1-4757-5803-0_4 |
0.54 |
|
| 1989 |
Weiss A, Fraser JD, Desai DM, Goldsmith MA. Signal Transduction by the T Cell Antigen Receptor Seminars in Immunology. 3: 687-692. DOI: 10.1007/978-3-642-83755-5_93 |
0.506 |
|
| 1988 |
Goldsmith MA, Dazin PF, Weiss A. At least two non-antigen-binding molecules are required for signal transduction by the T-cell antigen receptor Proceedings of the National Academy of Sciences of the United States of America. 85: 8613-8617. PMID 3263650 DOI: 10.1073/Pnas.85.22.8613 |
0.502 |
|
| 1988 |
Goldsmith MA, Weiss A. Early signal transduction by the antigen receptor without commitment to T cell activation Science. 240: 1029-1031. PMID 3259335 DOI: 10.1126/Science.3259335 |
0.459 |
|
| 1988 |
Goldsmith MA, Weiss A. Generation and analysis of a T-lymphocyte somatic mutant for studying molecular aspects of signal transduction by the antigen receptor Annals of the New York Academy of Sciences. 546: 91-103. PMID 3073703 DOI: 10.1111/J.1749-6632.1988.Tb21623.X |
0.467 |
|
| 1988 |
Goldsmith MA, Weiss A. Function of the antigen receptor in T cell activation Advances in Experimental Medicine and Biology. 234: 195-211. PMID 3063086 DOI: 10.1007/978-1-4757-1980-2_13 |
0.42 |
|
| 1988 |
Morley BJ, Chin KN, Newton ME, Weiss A. The lysine residue in the membrane-spanning domain of the beta chain is necessary for cell surface expression of the T cell antigen receptor. The Journal of Experimental Medicine. 168: 1971-8. PMID 2974063 DOI: 10.1084/Jem.168.6.1971 |
0.381 |
|
| 1988 |
Loh EY, Lanier LL, Turck CW, Littman DR, Davis MM, Chien YH, Weiss A. Identification and sequence of a fourth human T cell antigen receptor chain. Nature. 330: 569-72. PMID 2825032 DOI: 10.1038/330569A0 |
0.441 |
|
| 1988 |
Imboden JB, Weiss A. The initiation of human T lymphocyte activation. Progress in Allergy. 42: 246-279. DOI: 10.1159/000415509 |
0.393 |
|
| 1988 |
Goldsmith MA, Weiss A. New clues about T-cell antigen receptor complex function Trends in Immunology. 9: 222-229. DOI: 10.1016/0167-5699(88)91219-4 |
0.44 |
|
| 1987 |
Bonyhadi M, Weiss A, Tucker PW, Tigelaar RE, Allison JP. Delta is the Cx-gene product in the γ/δ antigen receptor of dendritic epidermal cells Nature. 330: 574-576. PMID 3500417 DOI: 10.1038/330574A0 |
0.418 |
|
| 1987 |
Phillips JH, Weiss A, Gemlo BT, Rayner AA, Lanier LL. Evidence that the T cell antigen receptor may not be involved in cytotoxicity mediated by gamma/delta and alpha/beta thymic cell lines. The Journal of Experimental Medicine. 166: 1579-84. PMID 3500263 DOI: 10.1084/Jem.166.5.1579 |
0.375 |
|
| 1987 |
Lanier LL, Serafini AT, Ruitenberg JJ, Cwirla S, Federspiel NA, Phillips JH, Allison JP, Weiss A. The gamma T-cell antigen receptor. Journal of Clinical Immunology. 7: 429-40. PMID 3320076 DOI: 10.1007/Bf00915052 |
0.475 |
|
| 1987 |
Goldsmith MA, Weiss A. Isolation and characterization of a T-lymphocyte somatic mutant with altered signal transduction by the antigen receptor Proceedings of the National Academy of Sciences of the United States of America. 84: 6879-6883. PMID 3309950 DOI: 10.1073/Pnas.84.19.6879 |
0.406 |
|
| 1987 |
Gunter KC, Germain RN, Kroczek RA, Saito T, Yokoyama WM, Chan C, Weiss A, Shevach EM. Thy-1-mediated T-cell activation requires co-expression of CD3/Ti complex. Nature. 326: 505-7. PMID 3104795 DOI: 10.1038/326505A0 |
0.471 |
|
| 1987 |
Littman DR, Newton M, Crommie D, Ang SL, Seidman JG, Gettner SN, Weiss A. Characterization of an expressed CD3-associated Ti gamma-chain reveals C gamma domain polymorphism. Nature. 326: 85-8. PMID 3102973 DOI: 10.1038/326085A0 |
0.402 |
|
| 1987 |
Durand DB, Bush MR, Morgan JG, Weiss A, Crabtree GR. A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor Journal of Experimental Medicine. 165: 395-407. PMID 3102668 DOI: 10.1084/Jem.165.2.395 |
0.402 |
|
| 1987 |
Saito T, Weiss A, Miller J, Norcross MA, Germain RN. Specific antigen-Ia activation of transfected human T cells expressing murine Ti alpha beta-human T3 receptor complexes. Nature. 325: 125-30. PMID 3027582 DOI: 10.1038/325125A0 |
0.405 |
|
| 1987 |
Weiss A, Imboden JB. Cell surface molecules and early events involved in human T lymphocyte activation. Advances in Immunology. 41: 1-38. PMID 2961214 DOI: 10.1016/S0065-2776(08)60029-2 |
0.514 |
|
| 1987 |
Havran WL, Poenie M, Kimura J, Tsien R, Weiss A, Allison JP. Expression and function of the CD3-antigen receptor on murine CD4+8+ thymocytes. Nature. 330: 170-3. PMID 2959867 DOI: 10.1038/330170A0 |
0.444 |
|
| 1987 |
Weiss A, Imboden J, Hardy K, Stobo J. The role of the antigen receptor/T3 complex in T-cell activation. Advances in Experimental Medicine and Biology. 213: 45-9. PMID 2957896 DOI: 10.1007/978-1-4684-5323-2_5 |
0.366 |
|
| 1987 |
Lancki DW, Weiss A, Fitch FW. Requirements for triggering of lysis by cytolytic T lymphocyte clones. Journal of Immunology (Baltimore, Md. : 1950). 138: 3646-53. PMID 2953785 |
0.591 |
|
| 1987 |
Lanier LL, Federspiel NA, Ruitenberg JJ, Phillips JH, Allison JP, Littman D, Weiss A. The T cell antigen receptor complex expressed on normal peripheral blood CD4-, CD8- T lymphocytes. A CD3-associated disulfide-linked gamma chain heterodimer. The Journal of Experimental Medicine. 165: 1076-94. PMID 2435832 DOI: 10.1084/Jem.165.4.1076 |
0.449 |
|
| 1986 |
Lanier LL, Weiss A. Presence of Ti (WT31) negative T lymphocytes in normal blood and thymus Nature. 324: 268-270. PMID 3491323 DOI: 10.1038/324268A0 |
0.464 |
|
| 1986 |
Weiss A, Newton M, Crommie D. Expression of T3 in association with a molecule distinct from the T-cell antigen receptor heterodimer. Proceedings of the National Academy of Sciences of the United States of America. 83: 6998-7002. PMID 3092224 DOI: 10.1073/Pnas.83.18.6998 |
0.433 |
|
| 1986 |
Weiss A, Imboden J, Hardy K, Manger B, Terhorst C, Stobo J. The role of the T3/antigen receptor complex in T-cell activation. Annual Review of Immunology. 4: 593-619. PMID 2939858 DOI: 10.1146/Annurev.Iy.04.040186.003113 |
0.505 |
|
| 1986 |
Manger B, Hardy KJ, Weiss A, Stobo JD. Differential effect of cyclosporin A on activation signaling in human T cell lines. The Journal of Clinical Investigation. 77: 1501-6. PMID 2422208 DOI: 10.1172/Jci112464 |
0.413 |
|
| 1985 |
Ohashi PS, Mak TW, Van Den Elsen P, Yanagi Y, Yoshikai Y, Calman AF, Terhorst C, Stobo JD, Weiss A. Reconstitution of an active surface T3/T-cell antigen receptor by DNA transfer Nature. 316: 606-609. PMID 4033759 DOI: 10.1038/316606A0 |
0.433 |
|
| 1984 |
Weiss A, Imboden J, Shoback D, Stobo J. Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium. Proceedings of the National Academy of Sciences of the United States of America. 81: 4169-73. PMID 6234599 DOI: 10.1073/Pnas.81.13.4169 |
0.43 |
|
| 1984 |
Weiss A, Stobo JD. Requirement for the coexpression of T3 and the T cell antigen receptor on a malignant human T cell line. The Journal of Experimental Medicine. 160: 1284-99. PMID 6208306 DOI: 10.1084/Jem.160.5.1284 |
0.469 |
|
| 1984 |
Weiss A, Imboden J, Wiskocil R, Stobo J. The role of T3 in the activation of human T cells Journal of Clinical Immunology. 4: 165-173. PMID 6203926 DOI: 10.1007/Bf00914963 |
0.431 |
|
| 1982 |
MacDonald HR, Sekaly RP, Kanagawa O, Thiernesse N, Taswell C, Cerottini JC, Weiss A, Glasebrook AL, Engers HD, Kelso A, Brunner KT, Bron C. Cytolytic T lymphocyte clones. Immunobiology. 161: 84-106. PMID 6284635 DOI: 10.1016/S0171-2985(82)80020-X |
0.392 |
|
| 1981 |
Weiss A, Brunner KT, MacDonald HR, Cerottini JC. Antigenic specificity of the cytolytic T lymphocyte response to murine sarcoma virus-induced tumors. III. Characterization of cytolytic T lymphocyte clones specific for Moloney leukemia virus-associated cell surface antigens. The Journal of Experimental Medicine. 152: 1210-25. PMID 6159445 DOI: 10.1084/Jem.152.5.1210 |
0.387 |
|
| 1980 |
Stuart FP, McKearn TJ, Weiss A, Fitch FW. Suppression of rat renal allograft rejection by antigen and antibody. Immunological Reviews. 49: 127-65. PMID 6989746 DOI: 10.1111/J.1600-065X.1980.Tb00429.X |
0.487 |
|
| 1979 |
McKearn TJ, Weiss A, Stuart FP, Fitch FW. Selective suppression of humoral and cell-mediated immune responses to rat alloantigens by monoclonal antibodies produced by hybridoma cell lines. Transplantation Proceedings. 11: 932-5. PMID 377725 |
0.496 |
|
| 1978 |
Weiss A, Fitch FW. Suppression of the plaque-forming cell response by macrophages present in the normal rat spleen. Journal of Immunology (Baltimore, Md. : 1950). 120: 357-9. PMID 621383 |
0.504 |
|
| 1978 |
Weiss A, Fitch FW, McKearn TJ, Stuart FP. Immunological memory is regulated in the enhanced rat renal allograft recipient. Nature. 273: 662-4. PMID 351414 DOI: 10.1038/273662A0 |
0.509 |
|
| 1978 |
McKearn TJ, Sarmiento M, Weiss A, Stuart FP, Fitch FW. Selective suppression of reactivity to rat histocompatibility antigens by hybridoma antibodies. Current Topics in Microbiology and Immunology. 81: 61-5. PMID 308442 DOI: 10.1007/978-3-642-67448-8_10 |
0.517 |
|
| 1978 |
Weiss A, Stuart FP, Fitch FW. Absence of immunologic memory in recipients of enhanced renal allografts. Surgical Forum. 29: 330-3. PMID 162608 |
0.401 |
|
| 1978 |
Weiss A, Stuart FP, Fitch FW. Immune reactivity of cells from long-term rat renal allograft survivors. Transplantation. 26: 346-52. PMID 151955 DOI: 10.1097/00007890-197811000-00015 |
0.515 |
|
| 1978 |
Fitch FW, Weiss A, McKearn TJ, Stuart FP. Graft enhancement and antiidiotypic antibody. Lymphocytes from long-term rat renal allograft recipients have normal responsiveness in vitro. Transplantation Proceedings. 10: 367-72. PMID 79259 |
0.43 |
|
| 1977 |
Weiss A, Fitch FW. Macrophages suppress CTL generation in rat mixed leukocyte cultures. Journal of Immunology (Baltimore, Md. : 1950). 119: 510-6. PMID 142114 |
0.522 |
|
| 1972 |
Edidin M, Weiss A. Antigen cap formation in cultured fibroblasts: a reflection of membrane fluidity and of cell motility Proceedings of the National Academy of Sciences of the United States of America. 69: 2456-2459. PMID 4560687 DOI: 10.1073/Pnas.69.9.2456 |
0.339 |
|
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