Sergey M. Bezrukov - Publications

Affiliations: 
NIH (NICHD) 

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Rostovtseva TK, Weinrich M, Jacobs D, Rosencrans WM, Bezrukov SM. Dimeric Tubulin Modifies Mechanical Properties of Lipid Bilayer, as Probed Using Gramicidin A Channel. International Journal of Molecular Sciences. 25. PMID 38396879 DOI: 10.3390/ijms25042204  0.315
2023 Nestorovich EM, Bezrukov SM. Beta-Barrel Channel Response to High Electric Fields: Functional Gating or Reversible Denaturation? International Journal of Molecular Sciences. 24. PMID 38068977 DOI: 10.3390/ijms242316655  0.451
2023 Dagdug L, Berezhkovskii AM, Bezrukov SM. Diffusion Resistance of Segmented Channels. The Journal of Physical Chemistry. B. 127: 7291-7298. PMID 37566701 DOI: 10.1021/acs.jpcb.3c04520  0.512
2022 Ngo VA, Queralt-Martín M, Khan F, Bergdoll L, Abramson J, Bezrukov SM, Rostovtseva TK, Hoogerheide DP, Noskov SY. The Single Residue K12 Governs the Exceptional Voltage Sensitivity of Mitochondrial Voltage-Dependent Anion Channel Gating. Journal of the American Chemical Society. 144: 14564-14577. PMID 35925797 DOI: 10.1021/jacs.2c03316  0.328
2022 Berezhkovskii AM, Bezrukov SM. Intrinsic diffusion resistance of a membrane channel, mean first-passage times between its ends, and equilibrium unidirectional fluxes. The Journal of Chemical Physics. 156: 071103. PMID 35183069 DOI: 10.1063/5.0082482  0.497
2021 Hoogerheide DP, Gurnev PA, Rostovtseva TK, Bezrukov SM. Voltage-activated complexation of α-synuclein with three diverse β-barrel channels: VDAC, MspA, and α-hemolysin. Proteomics. e2100060. PMID 34813679 DOI: 10.1002/pmic.202100060  0.388
2021 Rostovtseva TK, Bezrukov SM, Hoogerheide DP. Regulation of Mitochondrial Respiration by VDAC Is Enhanced by Membrane-Bound Inhibitors with Disordered Polyanionic C-Terminal Domains. International Journal of Molecular Sciences. 22. PMID 34298976 DOI: 10.3390/ijms22147358  0.307
2021 Dagdug L, Berezhkovskii AM, Zitserman VY, Bezrukov SM. Effective diffusivity of a Brownian particle in a two-dimensional periodic channel of abruptly alternating width. Physical Review. E. 103: 062106. PMID 34271681 DOI: 10.1103/PhysRevE.103.062106  0.397
2021 Berezhkovskii AM, Bezrukov SM, Makarov DE. Localized potential well vs binding site: Mapping solute dynamics in a membrane channel onto one-dimensional description. The Journal of Chemical Physics. 154: 111101. PMID 33752368 DOI: 10.1063/5.0044044  0.378
2021 Skvortsov AT, Dagdug L, Berezhkovskii AM, MacGillivray IR, Bezrukov SM. Evaluating diffusion resistance of a constriction in a membrane channel by the method of boundary homogenization. Physical Review. E. 103: 012408. PMID 33601596 DOI: 10.1103/PhysRevE.103.012408  0.399
2021 Berezhkovskii AM, Pustovoit MA, Bezrukov SM. Fluxes of non-interacting and strongly repelling particles through a single conical channel: Analytical results and their numerical tests. Chemical Physics. 375: 523-528. PMID 21057663 DOI: 10.1016/j.chemphys.2010.04.040  0.33
2020 Queralt-Martín M, Hoogerheide DP, Noskov SY, Berezhkovskii AM, Rostovtseva TK, Bezrukov SM. VDAC gating thermodynamics, but not gating kinetics, are virtually temperature-independent. Biophysical Journal. PMID 33189678 DOI: 10.1016/j.bpj.2020.10.039  0.398
2020 Rostovtseva TK, Queralt-Martín M, Rosencrans WM, Bezrukov SM. Targeting the Multiple Physiologic Roles of VDAC With Steroids and Hydrophobic Drugs. Frontiers in Physiology. 11: 446. PMID 32457654 DOI: 10.3389/fphys.2020.00446  0.34
2020 Hoogerheide DP, Gurnev PA, Rostovtseva TK, Bezrukov SM. Effect of a post-translational modification mimic on protein translocation through a nanopore. Nanoscale. PMID 32400834 DOI: 10.1039/d0nr01577f  0.34
2020 Queralt-Martín M, Bergdoll L, Teijido O, Munshi N, Jacobs D, Kuszak AJ, Protchenko O, Reina S, Magrì A, De Pinto V, Bezrukov SM, Abramson J, Rostovtseva TK. A lower affinity to cytosolic proteins reveals VDAC3 isoform-specific role in mitochondrial biology. The Journal of General Physiology. 152. PMID 31935282 DOI: 10.1085/jgp.201912501  0.318
2020 Berezhkovskii AM, Bezrukov SM. Blocker escape kinetics from a membrane channel analyzed by mapping blocker diffusive dynamics onto a two-site model. The Journal of Chemical Physics. 150: 194103. PMID 31117787 DOI: 10.1063/1.5095594  0.505
2018 Queralt-Martín M, Bergdoll L, Jacobs D, Bezrukov SM, Abramson J, Rostovtseva TK. Assessing the role of residue E73 and lipid headgroup charge in VDAC1 voltage gating. Biochimica Et Biophysica Acta. Bioenergetics. PMID 30412693 DOI: 10.1016/j.bbabio.2018.11.001  0.33
2018 Berezhkovskii AM, Bezrukov SM. Effect of stochastic gating on the flux through a membrane channel: a steady-state approach. Journal of Physics. Condensed Matter : An Institute of Physics Journal. 30: 254006. PMID 29862987 DOI: 10.1088/1361-648X/aac4df  0.451
2018 Berezhkovskii AM, Bezrukov SM. Stochastic Gating as a Novel Mechanism for Channel Selectivity. Biophysical Journal. 114: 1026-1029. PMID 29448982 DOI: 10.1016/j.bpj.2018.01.007  0.51
2018 Berezhkovskii AM, Bezrukov SM. Effect of stochastic gating on channel-facilitated transport of non-interacting and strongly repelling solutes. The Journal of Chemical Physics. 147: 084109. PMID 28863525 DOI: 10.1063/1.4986902  0.494
2017 Weinrich M, Worcester DL, Bezrukov SM. Lipid nanodomains change ion channel function. Nanoscale. PMID 28858358 DOI: 10.1039/c7nr03926c  0.307
2017 Gurnev PA, Roark TC, Petrache HI, Sodt AJ, Bezrukov SM. Cation-Selective Channel Regulated by Anions According to Their Hofmeister Ranking. Angewandte Chemie (International Ed. in English). PMID 28198582 DOI: 10.1002/Anie.201611335  0.471
2016 Aksoyoglu MA, Podgornik R, Bezrukov SM, Gurnev PA, Muthukumar M, Parsegian VA. Size-dependent forced PEG partitioning into channels: VDAC, OmpC, and α-hemolysin. Proceedings of the National Academy of Sciences of the United States of America. PMID 27466408 DOI: 10.1073/Pnas.1602716113  0.387
2016 Noskov SY, Rostovtseva TK, Chamberlin AC, Teijido O, Jiang W, Bezrukov SM. Current state of theoretical and experimental studies of the voltage-dependent Anion Channel (VDAC). Biochimica Et Biophysica Acta. PMID 26940625 DOI: 10.1016/J.Bbamem.2016.02.026  0.412
2016 Verdel R, Dagdug L, Berezhkovskii AM, Bezrukov SM. Unbiased diffusion in two-dimensional channels with corrugated walls. The Journal of Chemical Physics. 144: 084106. PMID 26931680 DOI: 10.1063/1.4942470  0.428
2015 Bezrukov SM, Nestorovich EM. Inhibiting bacterial toxins by channel blockage. Pathogens and Disease. 74. PMID 26656888 DOI: 10.1093/femspd/ftv113  0.375
2015 Rappaport SM, Teijido O, Hoogerheide DP, Rostovtseva TK, Berezhkovskii AM, Bezrukov SM. Conductance hysteresis in the voltage-dependent anion channel. European Biophysics Journal : Ebj. 44: 465-72. PMID 26094068 DOI: 10.1007/s00249-015-1049-2  0.376
2014 Teijido O, Rappaport SM, Chamberlin A, Noskov SY, Aguilella VM, Rostovtseva TK, Bezrukov SM. Acidification asymmetrically affects voltage-dependent anion channel implicating the involvement of salt bridges. The Journal of Biological Chemistry. 289: 23670-82. PMID 24962576 DOI: 10.1074/Jbc.M114.576314  0.424
2014 Gurnev PA, Yap TL, Pfefferkorn CM, Rostovtseva TK, Berezhkovskii AM, Lee JC, Parsegian VA, Bezrukov SM. Alpha-synuclein lipid-dependent membrane binding and translocation through the α-hemolysin channel. Biophysical Journal. 106: 556-65. PMID 24507596 DOI: 10.1016/J.Bpj.2013.12.028  0.462
2013 Noskov SY, Rostovtseva TK, Bezrukov SM. ATP transport through VDAC and the VDAC-tubulin complex probed by equilibrium and nonequilibrium MD simulations. Biochemistry. 52: 9246-56. PMID 24245503 DOI: 10.1021/Bi4011495  0.41
2012 Nestorovich EM, Karginov VA, Berezhkovskii AM, Parsegian VA, Bezrukov SM. Kinetics and thermodynamics of binding reactions as exemplified by anthrax toxin channel blockage with a cationic cyclodextrin derivative. Proceedings of the National Academy of Sciences of the United States of America. 109: 18453-8. PMID 23100532 DOI: 10.1073/Pnas.1208771109  0.399
2012 Gurnev PA, Bezrukov SM. Inversion of membrane surface charge by trivalent cations probed with a cation-selective channel. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 15824-30. PMID 23088396 DOI: 10.1021/la302676t  0.433
2012 Bezrukov SM, Liu X, Karginov VA, Wein AN, Leppla SH, Popoff MR, Barth H, Nestorovich EM. Interactions of high-affinity cationic blockers with the translocation pores of B. anthracis, C. botulinum, and C. perfringens binary toxins. Biophysical Journal. 103: 1208-17. PMID 22995493 DOI: 10.1016/j.bpj.2012.07.050  0.417
2012 Gurnev PA, Queralt-Martin M, Aguilella VM, Rostovtseva TK, Bezrukov SM. Probing tubulin-blocked state of VDAC by varying membrane surface charge. Biophysical Journal. 102: 2070-6. PMID 22824270 DOI: 10.1016/j.bpj.2012.03.058  0.385
2011 Rostovtseva TK, Bezrukov SM. VDAC inhibition by tubulin and its physiological implications. Biochimica Et Biophysica Acta. 1818: 1526-35. PMID 22100746 DOI: 10.1016/j.bbamem.2011.11.004  0.361
2011 Sheldon KL, Maldonado EN, Lemasters JJ, Rostovtseva TK, Bezrukov SM. Phosphorylation of voltage-dependent anion channel by serine/threonine kinases governs its interaction with tubulin. Plos One. 6: e25539. PMID 22022409 DOI: 10.1371/Journal.Pone.0025539  0.341
2011 Gurnev PA, Rostovtseva TK, Bezrukov SM. Tubulin-blocked state of VDAC studied by polymer and ATP partitioning. Febs Letters. 585: 2363-6. PMID 21722638 DOI: 10.1016/j.febslet.2011.06.008  0.452
2010 Nestorovich EM, Karginov VA, Bezrukov SM. Polymer partitioning and ion selectivity suggest asymmetrical shape for the membrane pore formed by epsilon toxin. Biophysical Journal. 99: 782-9. PMID 20682255 DOI: 10.1016/j.bpj.2010.05.014  0.355
2010 Nestorovich EM, Karginov VA, Berezhkovskii AM, Bezrukov SM. Blockage of anthrax PA63 pore by a multicharged high-affinity toxin inhibitor. Biophysical Journal. 99: 134-43. PMID 20655841 DOI: 10.1016/j.bpj.2010.03.070  0.46
2009 Berezhkovskii AM, Pustovoit MA, Bezrukov SM. Entropic effects in channel-facilitated transport: interparticle interactions break the flux symmetry. Physical Review. E, Statistical, Nonlinear, and Soft Matter Physics. 80: 020904. PMID 19792070 DOI: 10.1103/PhysRevE.80.020904  0.355
2009 Weinrich M, Rostovtseva TK, Bezrukov SM. Lipid-dependent effects of halothane on gramicidin channel kinetics: a new role for lipid packing stress. Biochemistry. 48: 5501-3. PMID 19405539 DOI: 10.1021/bi900494y  0.411
2009 Alcaraz A, Nestorovich EM, López ML, García-Giménez E, Bezrukov SM, Aguilella VM. Diffusion, exclusion, and specific binding in a large channel: a study of OmpF selectivity inversion. Biophysical Journal. 96: 56-66. PMID 19134471 DOI: 10.1016/j.bpj.2008.09.024  0.463
2009 Zitserman VY, Berezhkovskii AM, Pustovoit MA, Bezrukov SM. Relaxation and fluctuations of the number of particles in a membrane channel at arbitrary particle-channel interaction. The Journal of Chemical Physics. 129: 095101. PMID 19044889 DOI: 10.1063/1.2972981  0.442
2009 Rostovtseva TK, Bezrukov SM. VDAC regulation: role of cytosolic proteins and mitochondrial lipids. Journal of Bioenergetics and Biomembranes. 40: 163-70. PMID 18654841 DOI: 10.1007/s10863-008-9145-y  0.32
2008 Rostovtseva TK, Sheldon KL, Hassanzadeh E, Monge C, Saks V, Bezrukov SM, Sackett DL. Tubulin binding blocks mitochondrial voltage-dependent anion channel and regulates respiration. Proceedings of the National Academy of Sciences of the United States of America. 105: 18746-51. PMID 19033201 DOI: 10.1073/pnas.0806303105  0.375
2008 Rostovtseva TK, Petrache HI, Kazemi N, Hassanzadeh E, Bezrukov SM. Interfacial polar interactions affect gramicidin channel kinetics. Biophysical Journal. 94: L23-5. PMID 18055540 DOI: 10.1529/Biophysj.107.120261  0.31
2007 Bezrukov SM, Berezhkovskii AM, Szabo A. Diffusion model of solute dynamics in a membrane channel: mapping onto the two-site model and optimizing the flux. The Journal of Chemical Physics. 127: 115101. PMID 17887882 DOI: 10.1063/1.2766720  0.471
2007 Ostroumova OS, Gurnev PA, Schagina LV, Bezrukov SM. Asymmetry of syringomycin E channel studied by polymer partitioning. Febs Letters. 581: 804-8. PMID 17289034 DOI: 10.1016/j.febslet.2007.01.063  0.355
2006 Rostovtseva TK, Kazemi N, Weinrich M, Bezrukov SM. Voltage gating of VDAC is regulated by nonlamellar lipids of mitochondrial membranes. The Journal of Biological Chemistry. 281: 37496-506. PMID 16990283 DOI: 10.1074/jbc.M602548200  0.369
2006 Karginov VA, Nestorovich EM, Yohannes A, Robinson TM, Fahmi NE, Schmidtmann F, Hecht SM, Bezrukov SM. Search for cyclodextrin-based inhibitors of anthrax toxins: synthesis, structural features, and relative activities. Antimicrobial Agents and Chemotherapy. 50: 3740-53. PMID 16982795 DOI: 10.1128/Aac.00693-06  0.317
2006 Berezhkovskii AM, Hummer G, Bezrukov SM. Identity of distributions of direct uphill and downhill translocation times for particles traversing membrane channels. Physical Review Letters. 97: 20601. PMID 16907424 DOI: 10.1103/Physrevlett.97.020601  0.376
2006 Nestorovich EM, Sugawara E, Nikaido H, Bezrukov SM. Pseudomonas aeruginosa porin OprF. Properties of the channel Journal of Biological Chemistry. 281: 16230-16237. PMID 16617058 DOI: 10.1074/Jbc.M600650200  0.411
2006 Kullman L, Gurnev PA, Winterhalter M, Bezrukov SM. Functional subconformations in protein folding: evidence from single-channel experiments. Physical Review Letters. 96: 038101. PMID 16486775 DOI: 10.1103/PhysRevLett.96.038101  0.375
2005 Danelon C, Nestorovich EM, Winterhalter M, Ceccarelli M, Bezrukov SM. Interaction of zwitterionic penicillins with the OmpF channel facilitates their translocation. Biophysical Journal. 90: 1617-27. PMID 16339889 DOI: 10.1529/biophysj.105.075192  0.454
2005 Bezrukov SM, Krasilnikov OV, Yuldasheva LN, Berezhkovskii AM, Rodrigues CG. Field-dependent effect of crown ether (18-crown-6) on ionic conductance of alpha-hemolysin channels. Biophysical Journal. 87: 3162-71. PMID 15507690 DOI: 10.1529/biophysj.104.044453  0.461
2005 Alcaraz A, Nestorovich EM, Aguilella-Arzo M, Aguilella VM, Bezrukov SM. Salting out the ionic selectivity of a wide channel: the asymmetry of OmpF. Biophysical Journal. 87: 943-57. PMID 15298901 DOI: 10.1529/biophysj.104/043414  0.462
2004 Berezhkovskii AM, Bezrukov SM. Optimizing transport of metabolites through large channels: molecular sieves with and without binding. Biophysical Journal. 88: L17-9. PMID 15626697 DOI: 10.1529/biophysj.104.057588  0.43
2004 Rostovtseva TK, Antonsson B, Suzuki M, Youle RJ, Colombini M, Bezrukov SM. Bid, but not Bax, regulates VDAC channels. The Journal of Biological Chemistry. 279: 13575-83. PMID 14729675 DOI: 10.1074/Jbc.M310593200  0.322
2004 Nestorovich EM, Rostovtseva TK, Bezrukov SM. Residue ionization and ion transport through OmpF channels. Biophysical Journal. 85: 3718-29. PMID 14645063 DOI: 10.1016/S0006-3495(03)74788-2  0.446
2002 Nestorovich EM, Danelon C, Winterhalter M, Bezrukov SM. Designed to penetrate: time-resolved interaction of single antibiotic molecules with bacterial pores. Proceedings of the National Academy of Sciences of the United States of America. 99: 9789-94. PMID 12119404 DOI: 10.1073/pnas.152206799  0.429
2002 Malev VV, Schagina LV, Gurnev PA, Takemoto JY, Nestorovich EM, Bezrukov SM. Syringomycin E channel: a lipidic pore stabilized by lipopeptide? Biophysical Journal. 82: 1985-94. PMID 11916856 DOI: 10.1016/S0006-3495(02)75547-1  0.448
2002 Kullman L, Winterhalter M, Bezrukov SM. Transport of maltodextrins through maltoporin: a single-channel study. Biophysical Journal. 82: 803-12. PMID 11806922 DOI: 10.1016/S0006-3495(02)75442-8  0.488
2002 Rostovtseva TK, Komarov A, Bezrukov SM, Colombini M. Dynamics of nucleotides in VDAC channels: structure-specific noise generation. Biophysical Journal. 82: 193-205. PMID 11751308 DOI: 10.1016/S0006-3495(02)75386-1  0.381
2002 Rostovtseva TK, Nestorovich EM, Bezrukov SM. Partitioning of differently sized poly(ethylene glycol)s into OmpF porin. Biophysical Journal. 82: 160-9. PMID 11751305 DOI: 10.1016/S0006-3495(02)75383-6  0.304
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