John C. Newman, MD, PhD - Publications

Affiliations: 
Buck Institute for Research on Aging 
 Geriatrics UCSF School of Medicine 
Area:
Geroscience, aging, geriatrics, delirium, frailty, ketone bodies
Website:
https://www.buckinstitute.org/lab/newman-lab/

29 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nomura M, Murad NF, Madhavan SS, Eap B, Garcia TY, Aguirre CG, Verdin E, Ellerby L, Furman D, Newman JC. A ketogenic diet reduces age-induced chronic neuroinflammation in mice Running title: ketogenic diet and brain inflammaging. Biorxiv : the Preprint Server For Biology. PMID 38106160 DOI: 10.1101/2023.12.01.569598  0.572
2022 Strong R, Miller RA, Cheng CJ, Nelson JF, Gelfond J, Allani SK, Diaz V, Dorigatti AO, Dorigatti J, Fernandez E, Galecki A, Ginsburg B, Hamilton KL, Javors MA, Kornfeld K, ... ... Newman J, et al. Lifespan benefits for the combination of rapamycin plus acarbose and for captopril in genetically heterogeneous mice. Aging Cell. e13724. PMID 36179270 DOI: 10.1111/acel.13724  0.449
2021 Chen O, Blonquist TM, Mah E, Sanoshy K, Beckman D, Nieman KM, Winters BL, Anthony JC, Verdin E, Newman JC, Stubbs BJ. Tolerability and Safety of a Novel Ketogenic Ester, Bis-Hexanoyl (R)-1,3-Butanediol: A Randomized Controlled Trial in Healthy Adults. Nutrients. 13. PMID 34208742 DOI: 10.3390/nu13062066  0.397
2021 Stubbs BJ, Nikiforov AI, Rihner MO, Weston SL, Higley N, Stump DG, Krane GA, Gadupudi G, Verdin E, Newman JC. Toxicological Evaluation of the ketogenic ester Bis Hexanoyl (R)-1,3-Butanediol: Subchronic Toxicity in Sprague Dawley Rats. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 112084. PMID 33621607 DOI: 10.1016/j.fct.2021.112084  0.384
2021 Stubbs BJ, Nikiforov AI, Rihner MO, Weston S, Higley N, Roy S, Dakoulas E, Verdin E, Newman JC. Genetic Toxicity Studies of the Ketogenic Ester Bis Hexanoyl (R)-1,3-Butanediol. International Journal of Toxicology. 1091581821991772. PMID 33611970 DOI: 10.1177/1091581821991772  0.417
2020 Yurista SR, Matsuura TR, Silljé HHW, Nijholt KT, McDaid KS, Shewale SV, Leone TC, Newman JC, Verdin E, van Veldhuisen DJ, de Boer RA, Kelly DP, Westenbrink BD. Ketone Ester Treatment Improves Cardiac Function and Reduces Pathologic Remodeling in Preclinical Models of Heart Failure. Circulation. Heart Failure. CIRCHEARTFAILURE1200. PMID 33356362 DOI: 10.1161/CIRCHEARTFAILURE.120.007684  0.394
2020 Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, ... ... Newman J, et al. Author Correction: Senescent cells promote tissue NAD decline during ageing via the activation of CD38 macrophages. Nature Metabolism. PMID 33303985 DOI: 10.1038/s42255-020-00328-w  0.455
2020 Gut P, Matilainen S, Meyer JG, Pällijeff P, Richard J, Carroll CJ, Euro L, Jackson CB, Isohanni P, Minassian BA, Alkhater RA, Østergaard E, Civiletto G, Parisi A, Thevenet J, ... ... Newman JC, et al. SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease. Nature Communications. 11: 5927. PMID 33230181 DOI: 10.1038/s41467-020-19743-4  0.483
2020 Stubbs BJ, Blade T, Mills S, Thomas J, Yufei X, Nelson F, Higley N, Nikiforov AI, Rhiner MO, Verdin E, Newman JC. In Vitro Stability and In Vivo Pharmacokinetics of the Novel Ketogenic Ester, Bis Hexanoyl (R)-1,3-Butanediol. Food and Chemical Toxicology : An International Journal Published For the British Industrial Biological Research Association. 111859. PMID 33212214 DOI: 10.1016/j.fct.2020.111859  0.432
2020 Covarrubias AJ, Kale A, Perrone R, Lopez-Dominguez JA, Pisco AO, Kasler HG, Schmidt MS, Heckenbach I, Kwok R, Wiley CD, Wong HS, Gibbs E, Iyer SS, Basisty N, Wu Q, ... ... Newman J, et al. Senescent cells promote tissue NAD decline during ageing via the activation of CD38 macrophages. Nature Metabolism. 2: 1265-1283. PMID 33199924 DOI: 10.1038/s42255-020-00305-3  0.493
2020 Stubbs BJ, Koutnik AP, Goldberg EL, Upadhyay V, Turnbaugh PJ, Verdin E, Newman JC. Investigating Ketone Bodies as Immunometabolic Countermeasures against Respiratory Viral Infections. Med (New York, N.Y.). PMID 32838361 DOI: 10.1016/j.medj.2020.06.008  0.421
2020 Ang QY, Alexander M, Newman JC, Tian Y, Cai J, Upadhyay V, Turnbaugh JA, Verdin E, Hall KD, Leibel RL, Ravussin E, Rosenbaum M, Patterson AD, Turnbaugh PJ. Ketogenic Diets Alter the Gut Microbiome Resulting in Decreased Intestinal Th17 Cells. Cell. PMID 32437658 DOI: 10.1016/J.Cell.2020.04.027  0.473
2019 Campisi J, Kapahi P, Lithgow GJ, Melov S, Newman JC, Verdin E. From discoveries in ageing research to therapeutics for healthy ageing. Nature. 571: 183-192. PMID 31292558 DOI: 10.1038/S41586-019-1365-2  0.451
2017 Newman JC, Covarrubias AJ, Zhao M, Yu X, Gut P, Ng CP, Huang Y, Haldar S, Verdin E. Ketogenic Diet Reduces Midlife Mortality and Improves Memory in Aging Mice. Cell Metabolism. 26: 547-557.e8. PMID 28877458 DOI: 10.1016/J.Cmet.2017.08.004  0.503
2017 Tognini P, Murakami M, Liu Y, Eckel-Mahan KL, Newman JC, Verdin E, Baldi P, Sassone-Corsi P. Distinct Circadian Signatures in Liver and Gut Clocks Revealed by Ketogenic Diet. Cell Metabolism. 26: 523-538.e5. PMID 28877456 DOI: 10.1016/J.Cmet.2017.08.015  0.465
2017 Newman JC, Verdin E. β-Hydroxybutyrate: A Signaling Metabolite. Annual Review of Nutrition. 37: 51-76. PMID 28826372 DOI: 10.1146/Annurev-Nutr-071816-064916  0.484
2016 Shirakawa K, Wang L, Man N, Maksimoska J, Sorum AW, Lim HW, Lee IS, Shimazu T, Newman JC, Schröder S, Ott M, Marmorstein R, Meier J, Nimer S, Verdin E. Salicylate, diflunisal and their metabolites inhibit CBP/p300 and exhibit anticancer activity. Elife. 5. PMID 27244239 DOI: 10.7554/Elife.11156  0.481
2014 Newman JC, Verdin E. β-hydroxybutyrate: much more than a metabolite. Diabetes Research and Clinical Practice. 106: 173-81. PMID 25193333 DOI: 10.1016/J.Diabres.2014.08.009  0.491
2014 Newman JC, Verdin E. Ketone bodies as signaling metabolites. Trends in Endocrinology and Metabolism: Tem. 25: 42-52. PMID 24140022 DOI: 10.1016/J.Tem.2013.09.002  0.496
2013 Rardin MJ, He W, Nishida Y, Newman JC, Carrico C, Danielson SR, Guo A, Gut P, Sahu AK, Li B, Uppala R, Fitch M, Riiff T, Zhu L, Zhou J, et al. SIRT5 regulates the mitochondrial lysine succinylome and metabolic networks. Cell Metabolism. 18: 920-33. PMID 24315375 DOI: 10.1016/J.Cmet.2013.11.013  0.499
2013 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW. Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. Proceedings of the National Academy of Sciences of the United States of America. 110: 6601-6. PMID 23576753 DOI: 10.1073/Pnas.1302961110  0.55
2013 Shimazu T, Hirschey MD, Newman J, He W, Shirakawa K, Le Moan N, Grueter CA, Lim H, Saunders LR, Stevens RD, Newgard CB, Farese RV, de Cabo R, Ulrich S, Akassoglou K, et al. Suppression of oxidative stress by β-hydroxybutyrate, an endogenous histone deacetylase inhibitor. Science (New York, N.Y.). 339: 211-4. PMID 23223453 DOI: 10.1126/Science.1227166  0.471
2012 Newman JC, He W, Verdin E. Mitochondrial protein acylation and intermediary metabolism: regulation by sirtuins and implications for metabolic disease. The Journal of Biological Chemistry. 287: 42436-43. PMID 23086951 DOI: 10.1074/Jbc.R112.404863  0.502
2012 He W, Newman JC, Wang MZ, Ho L, Verdin E. Mitochondrial sirtuins: regulators of protein acylation and metabolism. Trends in Endocrinology and Metabolism: Tem. 23: 467-76. PMID 22902903 DOI: 10.1016/J.Tem.2012.07.004  0.667
2012 Bailey AD, Gray LT, Pavelitz T, Newman JC, Horibata K, Tanaka K, Weiner AM. The conserved Cockayne syndrome B-piggyBac fusion protein (CSB-PGBD3) affects DNA repair and induces both interferon-like and innate antiviral responses in CSB-null cells. Dna Repair. 11: 488-501. PMID 22483866 DOI: 10.1016/J.Dnarep.2012.02.004  0.641
2008 Newman JC, Bailey AD, Fan HY, Pavelitz T, Weiner AM. An abundant evolutionarily conserved CSB-PiggyBac fusion protein expressed in Cockayne syndrome. Plos Genetics. 4: e1000031. PMID 18369450 DOI: 10.1371/Journal.Pgen.1000031  0.599
2006 Newman JC, Bailey AD, Weiner AM. Cockayne syndrome group B protein (CSB) plays a general role in chromatin maintenance and remodeling. Proceedings of the National Academy of Sciences of the United States of America. 103: 9613-8. PMID 16772382 DOI: 10.1073/Pnas.0510909103  0.519
2005 Newman JC, Weiner AM. L2L: a simple tool for discovering the hidden significance in microarray expression data. Genome Biology. 6: R81. PMID 16168088 DOI: 10.1186/Gb-2005-6-9-R81  0.453
2002 Newman JC, Weiner A. Measuring the immeasurable. Molecular Cell. 10: 437-9. PMID 12408812 DOI: 10.1016/S1097-2765(02)00661-5  0.436
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